1. The Effects of Transoral Incisionless Fundoplication on Chronic GERD Patients
- Author
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Bart J. Carter, Reginald Bell, Karl A. LeBlanc, Mark A. Fox, Tanja Gunsberger, Kevin M. Hoddinott, Erik B. Wilson, Peter G. Mavrelis, Glenn M. Ihde, David Dargis, William E. Barnes, Brian DaCosta Gill, Karim S. Trad, Mark G. Hausmann, Robert W. Sewell, Katherine D. Freeman, Emir Deljkich, Ahmad B. Shughoury, and Daniel G. Turgeon
- Subjects
Adult ,Male ,Natural Orifice Endoscopic Surgery ,medicine.medical_specialty ,Time Factors ,Adolescent ,Fundoplication ,Gastroenterology ,Young Adult ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Aged ,business.industry ,Reflux ,Heartburn ,Middle Aged ,medicine.disease ,humanities ,digestive system diseases ,Surgery ,Treatment Outcome ,Transoral incisionless fundoplication ,Chronic Disease ,Regurgitation (digestion) ,Gastroesophageal Reflux ,Quality of Life ,GERD ,Female ,medicine.symptom ,business ,Follow-Up Studies - Abstract
This study aimed to assess the impact of transoral incisionless fundoplication (TIF) on patients with chronic gastroesophageal reflux disease (GERD) at 12-month follow-up.Clinical outcomes of 100 consecutive patients with chronic GERD who underwent TIF between January 2010 and February 2011 were analyzed.There were no major complications reported. Esophageal acid exposure was normalized in 14/27 (52%) of patients who underwent 12-month pH testing. Seventy-four percent of all patients were off proton pump inhibitors versus 92% on daily proton pump inhibitors before TIF, P0.001. Daily bothersome heartburn and regurgitation symptoms were eliminated in 66/85 (78%) and 48/58 (83%) of patients. Median reflux symptom index score was reduced from 20 (0 to 41) to 5 (0 to 44), P0.001. Two patients reported de novo dysphagia and 1 patient reported bloating (scores 0 to 3). Six patients underwent revision; 5 laparoscopic Nissen fundoplication and 1 TIF.TIF provided a safe and effective therapeutic option for carefully selected patients with chronic GERD.
- Published
- 2014