Author: "Paweska, Janusz" / Topic: evaluation research and hemorrhagic fever - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Paweska, Janusz" Topic evaluation research Topic hemorrhagic fever

Author: Swanepoel, Robert, Smit, Sheilagh B., Rollin, Pierre E., Formenty, Pierre, Leman, Patricia A., Kemp, Alan, Burt, Felicity J., Grobbelaar, Antoinette A., Croft, Janice, Bausch, Daniel G., Zeller, Hervé, Leirs, Herwig, Braack, L. E. O., Libande, Modeste L., Zaki, Sherif, Nichol, Stuart T., Ksiazek, Thomas G., Paweska, Janusz T., Zeller, Hervé, and International Scientific and Technical Committee for Marburg Hemorrhagic Fever Control in the Democratic Republic of Congo
Subjects: MARBURG virus, ANIMALS, MINES & mineral resources, HEMORRHAGIC fever, BATS, BAT classification, RESEARCH, BIOLOGICAL evolution, ANIMAL experimentation, RESEARCH methodology, RNA, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, RNA viruses, VIRAL antibodies, MINERAL industries
Abstract: To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful. [ABSTRACT FROM AUTHOR]
Published: 2007
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Author: Wölfel, Roman, Paweska, Janusz T., Petersen, Nadine, Grobbelaar, Antoinette A., Leman, Patricia A., Hewson, Roger, Georges-Courbot, Marie-Claude, Papa, Anna, Günther, Stephan, Drosten, Christian, Wölfel, Roman, and Günther, Stephan
Subjects: *HEMORRHAGIC fever, *POLYMERASE chain reaction, *VIRUS diseases, *SERUM, *VIRUSES, *INFECTION, *DIAGNOSIS, *PATIENTS, *REVERSE transcriptase polymerase chain reaction, *RESEARCH, *GENETICS, *BIOLOGICAL evolution, *VIRAL load, *RESEARCH methodology, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies, *IMMUNITY, *RNA viruses, *STANDARDS, RESEARCH evaluation
Abstract: We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection. [ABSTRACT FROM AUTHOR]
Published: 2007
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Author: Palacios, Gustavo, Briese, Thomas, Kapoor, Vishal, Jabado, Omar, Zhiqiang Liu, Venter, Marietjie, Junhui Zhai, Renwick, Neil, Grolla, Allen, Geisbert, Thomas W., Drosten, Christian, Towner, Jonathan, Jingyue Ju, Paweska, Janusz, Nichol, Stuart T., Swanepoel, Robert, Feldmann, Heinz, Jahrling, Peter B., Lipkin, W. Ian, and Liu, Zhiqiang
Subjects: VIRUS diseases, COMMUNICABLE diseases, FEVER, ETIOLOGY of diseases, POLYMERASE chain reaction, PHYSICAL & theoretical chemistry, COMPARATIVE studies, COMPUTER software, DIFFERENTIAL diagnosis, HEMORRHAGIC fever, RESEARCH methodology, MEDICAL cooperation, RESEARCH, RESEARCH funding, EVALUATION research, DIAGNOSIS
Abstract: Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We describe a diagnostic system for rapid, multiplex polymerase chain reaction identification of 10 different causes of viral hemorrhagic fevers. [ABSTRACT FROM AUTHOR]
Published: 2006
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