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Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients.
- Source :
-
Emerging Infectious Diseases . Jul2007, Vol. 13 Issue 7, p1097-1100. 4p. 1 Diagram, 1 Chart, 1 Graph. - Publication Year :
- 2007
-
Abstract
- We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMORRHAGIC fever
*POLYMERASE chain reaction
*VIRUS diseases
*SERUM
*VIRUSES
*INFECTION
*DIAGNOSIS
*PATIENTS
*REVERSE transcriptase polymerase chain reaction
*RESEARCH
*GENETICS
*BIOLOGICAL evolution
*VIRAL load
*RESEARCH methodology
*MEDICAL cooperation
*EVALUATION research
*COMPARATIVE studies
*IMMUNITY
*RNA viruses
*STANDARDS
RESEARCH evaluation
Subjects
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 13
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 25690888
- Full Text :
- https://doi.org/10.3201/eid1307.070068