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34 results on '"Zheng, Yu-Guo"'

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1. Recent advancements in enzyme engineering via site-specific incorporation of unnatural amino acids.

2. Enzymatic asymmetric synthesis of chiral amino acids.

3. Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate.

4. Strategies for tailoring pH performances of glycoside hydrolases.

5. Constitutive expression of nitrilase from Rhodococcus zopfii for efficient biosynthesis of 2-chloronicotinic acid.

6. Biosynthesis of l-phosphinothricin with enzymes from chromosomal integrated expression in E. coli.

7. Highly efficient synthesis of rosuvastatin intermediate using a carbonyl reductase–cofactor co‐immobilized biocatalyst in the non‐aqueous biosystem.

8. Nitrilase: a promising biocatalyst in industrial applications for green chemistry.

9. Recent advances in the improvement of enzyme thermostability by structure modification.

10. Immobilization of Enzymes in/on Membranes and their Applications.

11. Highly regio- and enantioselective synthesis of chiral intermediate for pregabalin using one-pot bienzymatic cascade of nitrilase and amidase.

12. Identification and engineering of the key residues at the crevice-like binding site of lipases responsible for activity and substrate specificity.

13. A One-Step Biocatalytic Process for ( S)-4-Chloro-3-hydroxybutyronitrile using Halohydrin Dehalogenase: A Chiral Building Block for Atorvastatin.

14. Upscale production of ethyl ( S)-4-chloro-3-hydroxybutanoate by using carbonyl reductase coupled with glucose dehydrogenase in aqueous-organic solvent system.

15. Engineering of Thermomyces lanuginosus lipase Lip: creation of novel biocatalyst for efficient biosynthesis of chiral intermediate of Pregabalin.

16. Screening and Improving the Recombinant Nitrilases and Application in Biotransformation of Iminodiacetonitrile to Iminodiacetic Acid.

17. Characterization and application of a newly synthesized 2-deoxyribose-5-phosphate aldolase.

18. Asymmetric synthesis of ( R)-1,3-butanediol from 4-hydroxy-2-butanone by a newly isolated strain Candida krusei ZJB-09162.

19. Enzymatic production of 2-amino-2,3-dimethylbutyramide by cyanide-resistant nitrile hydratase.

20. Biosynthesis of p-methoxyphenylacetic acid from p-methoxyphenylacetonitrile by immobilized Bacillus subtilis ZJB-063

21. Inhibitory effect of valienamine on the enzymatic activity of honeybee (Apis cerana Fabr.) α-glucosidase

22. Encapsulation of recombinant Escherichia coli cells harboring nitrilase in surface-crosslinked hydrogel particles: A robust and durable biocatalyst for the hydrolysis of nitrile.

23. Combining fermentation to produce O-succinyl-l-homoserine and enzyme catalysis for the synthesis of l-methionine in one pot.

24. Enzyme cascade for biocatalytic deracemization of D,L-phosphinothricin.

25. Designing a novel (R)-ω-transaminase for asymmetric synthesis of sitagliptin intermediate via motif swapping and semi-rational design.

26. Efficient biosynthesis of (R)-3-amino-1-butanol by a novel (R)-selective transaminase from Actinobacteria sp.

27. Whole cell immobilization of refractory glucose isomerase using tris(hydroxymethyl)phosphine as crosslinker for preparation of high fructose corn syrup at elevated temperature.

28. Engineering of Talaromyces thermophilus lipase by altering its crevice-like binding site for highly efficient biocatalytic synthesis of chiral intermediate of Pregablin.

29. Reaction-kinetic model-guided biocatalyst engineering for dual-enzyme catalyzed bioreaction system.

30. Production of (R)-epichlorohydrin from 1,3-dichloro-2-propanol by two-step biocatalysis using haloalcohol dehalogenase and epoxide hydrolase in two-phase system.

31. Characterization of a newly synthesized epoxide hydrolase and its application in racemic resolution of (R,S)-epichlorohydrin

32. Efficient synthesis of (S)-epichlorohydrin in high yield by cascade biocatalysis with halohydrin dehalogenase and epoxide hydrolase mutants.

33. Rational design of halohydrin dehalogenase for efficient chiral epichlorohydrin production with high activity and enantioselectivity in aqueous-organic two-phase system.

34. A novel self-sufficient biocatalyst based on transaminase and pyridoxal 5′-phosphate covalent co-immobilization and its application in continuous biosynthesis of sitagliptin.

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