1. Evaluation of Leukocytes and Neutrophils, Markers of Inflammatory Syndrome in Preeclampsia.
- Author
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Mihu, Dan, Sabău, Lavinia, Costin, Nicolae, Ciortea, Răzvan, Oancea, Mihaela, and Măluţan, Andrei
- Subjects
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LEUCOCYTES , *NEUTROPHILS , *PREECLAMPSIA diagnosis , *PREGNANCY complications , *BIOMARKERS , *SEVERITY of illness index , *CONTROL groups , *HEMATOLOGY , *DIASTOLE (Cardiac cycle) - Abstract
Introduction: In pregnancies with preeclampsia, there is a generalized inflammatory response, which is much more intense than in normal pregnancy. Aim: To evaluate leukocytes and neutrophils in the serum of pregnant women with preeclampsia and to compare these values to normal pregnancy. To investigate a possible relation between the detected values and the severity of preeclamptic syndrome. Material and method: A transversal study was performed in three groups of patients: group 1 (preeclampsia), group 2 (normal pregnancy), group 3 (control). The samples were processed using a multichannel automated hematology analyzer - ACCOS 319. The results obtained were processed by descriptive and comparative statistical methods. Results: A significant increase in leukocyte and neutrophil values was found in preeclampsia compared to normal pregnancy. Also, for group 2 (PE), there was no correlation between the number of leukocytes, neutrophils, respectively, and SBP and uric acid values, but a significant correlation was found between the studied inflammatory markers and DBP values. Conclusions: Leukocyte and neutrophil values can be considered markers of the inflammatory syndrome present in preeclampsia. These parameters were positively correlated with DBP values. [ABSTRACT FROM AUTHOR]
- Published
- 2010