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Evaluation of Leukocytes and Neutrophils, Markers of Inflammatory Syndrome in Preeclampsia.

Authors :
Mihu, Dan
Sabău, Lavinia
Costin, Nicolae
Ciortea, Răzvan
Oancea, Mihaela
Măluţan, Andrei
Source :
Applied Medical Informatics. Sep2010, Vol. 27 Issue 3, p15-22. 8p. 2 Charts, 6 Graphs.
Publication Year :
2010

Abstract

Introduction: In pregnancies with preeclampsia, there is a generalized inflammatory response, which is much more intense than in normal pregnancy. Aim: To evaluate leukocytes and neutrophils in the serum of pregnant women with preeclampsia and to compare these values to normal pregnancy. To investigate a possible relation between the detected values and the severity of preeclamptic syndrome. Material and method: A transversal study was performed in three groups of patients: group 1 (preeclampsia), group 2 (normal pregnancy), group 3 (control). The samples were processed using a multichannel automated hematology analyzer - ACCOS 319. The results obtained were processed by descriptive and comparative statistical methods. Results: A significant increase in leukocyte and neutrophil values was found in preeclampsia compared to normal pregnancy. Also, for group 2 (PE), there was no correlation between the number of leukocytes, neutrophils, respectively, and SBP and uric acid values, but a significant correlation was found between the studied inflammatory markers and DBP values. Conclusions: Leukocyte and neutrophil values can be considered markers of the inflammatory syndrome present in preeclampsia. These parameters were positively correlated with DBP values. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
12245593
Volume :
27
Issue :
3
Database :
Academic Search Index
Journal :
Applied Medical Informatics
Publication Type :
Academic Journal
Accession number :
54279433