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The Institute for Nuclear Research and Nuclear Energy at the Bulgarian Academy of Sciences is building a cyclotron facility dedicated to production, and research and development of radiopharmaceuticals. 18F is of primary interest and the radiological characterization of the cyclotron and it’s vault with an 18O-target has shown that local shielding around the target will be useful in limiting the spatial distribution of emitted secondary particles and to decrease the activation of the vault walls. The current study shows preliminary numerical results on the optimization of local shielding around 18O-target for 18F production. For the purpose a simplified spherical geometry of the local shielding and the vault walls has been considered. Results for the production of residual nucleis in the vault walls been obtained. [ABSTRACT FROM AUTHOR]

The Institute for Nuclear Research and Nuclear Energy at the Bulgarian Academy of Sciences is preparing to operate a high-power cyclotron for production of isotopes for nuclear medicine. 67,68Ga are some of the target isotopes as studies have shown that both of them can be produced via direct proton irradiation with a cyclotron. The aim of this study is to assess numerically the production of both nuclides 67,68Ga via (p, xn) reactions on 67,68Zn-enriched solid targets. Various irradiation conditions are compared with respect to End Of Beam activity and contaminants. The FLUKA code is used for the simulations and the results are compared with published experimental data. [ABSTRACT FROM AUTHOR]