1. Synthesis and Antimicrobial Activity of Quinoxaline Based 1,2,3-Triazoles
- Author
-
A. Kishore Kumar, G. Ramesh, P. Jalapathi, and V. Sunitha
- Subjects
Drug ,Antifungal ,010405 organic chemistry ,medicine.drug_class ,media_common.quotation_subject ,Moderate activity ,General Chemistry ,010402 general chemistry ,Antimicrobial ,01 natural sciences ,Combinatorial chemistry ,0104 chemical sciences ,chemistry.chemical_compound ,Quinoxaline ,chemistry ,medicine ,Gentamicin ,media_common ,medicine.drug - Abstract
Synthesis and characterization of novel quinoxaline-1,2,3-triazole hybrid heterocyclic derivatives have been carried out, and their antimicrobial activity has been tested. Antibacterial and antifungal studies of the synthesized compounds have demonstrated high to moderate activity against the tested pathogens for most of those. Several products have been determined to be potent antimicrobial agents at concentrations of 75 and 100 µg/mL as compared to the standard drug Gentamicin.
- Published
- 2020