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Your search keyword '"D. C. Hsieh"' showing total 2 results
Start Over Author "D. C. Hsieh" Topic chemistry.chemical_compound
2 results on '"D. C. Hsieh"'

1. Orally Active Squalene Synthase Inhibitors: Bis((acyloxy)alkyl) Prodrugs of the α-Phosphonosulfonic Acid Moiety

Author

J. K. Rinehart, Shih-Jung Lan, Kern G. Jolibois, Richard E. Gregg, Lori Kunselman, John K. Dickson, D. C. Hsieh, Edward W. Petrillo, J. W. Hillyer, Stephen S. Kalinowski, T. W. Harrity, Kasim A. Mookhtiar, D. R. Magnin, Carl P. Ciosek, and Scott A. Biller

Subjects
chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, biology, Stereochemistry, Guinea Pigs, Administration, Oral, Ether, Prodrug, Chemical synthesis, Rats, chemistry.chemical_compound, Squalene, Farnesyl-Diphosphate Farnesyltransferase, chemistry, Enzyme inhibitor, Drug Discovery, biology.protein, Animals, Molecular Medicine, Moiety, Prodrugs, Enzyme Inhibitors, Sulfonic Acids, Alkyl, Hypolipidemic Agents
Published
1996

2. alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase

Author

D. C. Hsieh, T. W. Harrity, Janette V. H. Logan, Shih-Jung Lan, R. B. Sulsky, Carl P. Ciosek, Lori Kunselman, Ying Chen, Dorothy Slusarchyk, J. K. Rinehart, Olga M. Fryszman, D. R. Magnin, Lois C. Rich, John K. Dickson, Scott A. Biller, Ellen Sieber-McMaster, R. M. Lawrence, Kern G. Jolibois, and Sarah C. Traeger

Subjects
Stereochemistry, Molecular Conformation, chemistry.chemical_compound, Squalene, Biosynthesis, Cricetinae, Drug Discovery, Animals, Hypolipidemic Agents, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, biology, ATP synthase, Cholesterol, In vitro, Rats, Enzyme, Farnesyl-Diphosphate Farnesyltransferase, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Microsomes, Liver, Molecular Medicine, Sulfonic Acids
Published
1996

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