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24 results on '"Kenneth G. Carson"'

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1. Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa Using DNA-Encoded Small Molecule Library Screening

2. 864 Identification of a novel allosteric oral Cbl-b inhibitor that augmented T cell response and enhanced NK cell killing in vitro and in vivo

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3. Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes

4. 4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase

5. Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88

6. Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)

7. Novel Potent Inhibitors of Deoxycytidine Kinase Identified and Compared by Multiple Assays

8. Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

9. Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase

10. Synthesis and structure–Activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-Molecule antagonists for interleukin-8 receptor

11. Sulfonopeptide inhibitors of leukocyte adhesion

12. Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures1

13. Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase

14. ChemInform Abstract: Reductive Amination of Aldehydes and Ketones by Using Sodium Triacetoxyborohydride

15. ChemInform Abstract: Studies on Morpholinosphingolipids: Potent Inhibitors of Glucosylceramide Synthase

17. 5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase

18. Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors

19. The reactions of an o-quinone monoimide with some phenols

20. Curtius rearrangement in the 5-phenyl-1,4-benzodiazepine series. Unprecedented participation by an imine nitrogen

21. Reductive amination of aldehydes and ketones by using sodium triacetoxyborohydride

22. Small molecule antagonists of the CC chemokine receptor 4 (CCR4)

23. Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8)

24. Genetic and Chemical Inhibition of Sphingosine 1-Phosphate Lyase Results in Peripheral Lymphopenia and Alleviates Disease Development in Animal Models of Inflammation and Autoimmunity