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Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase
- Source :
- Tetrahedron Letters. 35:2659-2662
- Publication Year :
- 1994
- Publisher :
- Elsevier BV, 1994.
-
Abstract
- Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase. The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.
Details
- ISSN :
- 00404039
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........4f1ab9680de7efa3894b3d5a20e6914c
- Full Text :
- https://doi.org/10.1016/s0040-4039(00)76999-1