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In this article, we provide a theoretical discussion on the interactions between a template molecule and functional monomer(s) in the preparation of molecularly imprinted polymers (MIPs). Density functional theory (DFT) was used to compute the 3D structures, natural bond orbital, and binding energy in the template–monomer(s) complexes. Histamine (HA) and 2-(trifluoromethyl)acrylic acid (TFMAA) were, respectively, selected as the template and the monomer. The computational process was performed according to B3LYP method with 6-311 + (d,p) basis set under the different HA–TFMAA ratios from 1:1 to 1:10. The computational results show that the HA–TFMAA complex at the ratio of 1:5 yields no consequence. Furthermore, the HA–TFMAA complex at the ratio of 1:5 allowed the minimum binding energy and the steadiest condition, with four hydrogen bonds. Configurational simulations and theoretical calculations of the template–monomer complex can be used as an appropriate guiding tool for manufacturing MIPs with high specificity and selectivity, thereby avoiding repeated experiments and wastage of substantial time and investment.

An intermolecular iodoamination of allenamides with sulfonamides has been achieved under mild N-iodosuccinimide-mediated conditions delivering iodine-substituted allylamino Z-enamides in high regio- and stereoselectivity. These reactions proceed rapidly and tolerate a broad scope of substrates.

A new method was developed to synthesize iodine-substituted Z-enamides through N-iodosuccinimide-mediated intermolecular iodofunctionalization of allenamides with indoles, pyrroles, and furans. These reactions proceed rapidly and tolerate a broad scope of substrates. The conjugated sulfimide ion species probably acts as the key intermediate.

：The phosphate is low silicon carbonate collophane, gangue mainly dolomite. Apply to the reverse flotation technology, determine one-stage roughing and one-stage scavenging reverse flotation test process,Collector with paraffin soap oxidated,Inhibitor use sulfuric acid. By the reverse flotation process contain. When the ore grade is 20.11%,under the flow sheet can research qualified phosphate product with content of 33.95% in concentration and recovery of 62.06%.

Apatite is a valuable component of the collophane taken from Yunnan, as it is in the shape of oolith and contains a lot of carbon, and hence an effective benefication of the apatite is difficult to be occurred by means of concentration. Based on the results of both direct and reverse flotation tests, it shows that reverse flotation is effective in the benefication of the apatite to a certain extent. When reverse flotation is employed to treat the run-of-mine at a grade of 18.77%, the concentrate containing P2O5 24.04% at a recovery of 62.58% can be produced.

As one of major environmental endocrine disruptors (EEDs), bisphenol A (BPA) has been drawn increasingly lots of people in the world, which is also widely identified as an indispensable raw chemical in plastics production, food cans and dental composites. With increasing demand and production capacity of BPA, moreBPAwill enter into and contaminate the environment. So it has become a challenge that excess BPA jeopardizes the health of human being. Considering a pretty low dose of BPA existing in the environment, some advanced analysis techniques have been carried out to analysis BPA, such as HLPC, GC-MS, LC-MS. Compared with other physical and chemical treatment technology, biological treatment technology has the advantage of low cost and high efficiency.

Efficient charge transport across proper interfacial contacts is crucial in organic solar cells. In this paper, the surface of the P3HT:PCBM bulk heterojunction (BHJ) layer is treated with ethylene...

The phosphate is low silicon carbonate collophane, gangue mainly dolomite. determine one-stage roughing and one-stage scavenging reverse flotation test process,the grinding fineness of 92.86% -200 mesh.Collector with paraffin soap oxidated,Three acid of sulfuric acid, hydrochloric acid, nitric acid as an inhibitor for contrast test,With concentration of 10% sulfuric acid 10000 g/t can research qualified phosphate product with content of 33.95% in concentration and recovery of 62.06%.

Background Many of these therapies have been compared against placebos, but have not been directly compared against each other. To evaluate the efficacy and safety of several commonly used drugs for AIS directly or indirectly. Methods A systematic literature review was performed to identify randomized controlled trials (RCTs) published prior to April 2013 for AIS therapies. The primary outcome measures were the National Institutes of Health Stroke Scale (NIHSS) scores and the clinical effective rate. A fixed-effects meta-analysis and meta-regression are performed; lastly, performed a mixed treatment comparison was performed through the Bayesian methods. Results Outcome of Efficacy of therapies for acute ischemic stroke are as followed: All of the therapies mentioned above yielded results a more effective result than placebo, Sodium ozagrel (RR 3.86, 95%CI 3.18–4.61); Sodium ozagrel + edaravone (RR 9.60, 95%CI 7.04–13.06); Edaravone (RR 4.07, 95%CI 3.30–5.01); Edaravone + Kininogenase (RR 15.33, 95%CI 10.03–23.05). The significant difference in efficacy between edaravone monotherapy and Sodium ozagrel + edaravone was evident (RR 0.43, 95%CI 0.08–0.61) and was also significant between efficacy of edaravone + Kininogenase and Sodium ozagrel (RR 4.00, 95%CI 2.47–6.24). The differences between the risk and benefit were not significant when comparing Sodium ozagrel and edaravone or edaravone + Kininogenase and Sodium ozagrel + Edaravone for AIS. Outcome of the defect of neurological function: Placebo served a significant difference in treating the defects of neurological function compared with Sodium ozagrel (WMD = −3.11, 95%CI −4.43 to −1.79), Sodium ozagrel + edaravone (WMD = −6.25, 95%CI −7.96 to −4.54) and Edaravone + Kininogenase (WMD = −3.47, 95%CI −5.73 to −1.21). Conclusions It provides that the efficacy of edaravone monotherapy in treatment was not more effective than Sodium ozagrel + edaravone.The efficacy of edaravone + Kininogenase monotherapy in treatment was more effective than Sodium ozagrel. Edaravone + Kininogenase and Sodium ozagrel + Edaravone appeared the most effective treatments. And Sodium ozagrel, Sodium ozagrel + edaravone, Edaravone + Kininogenase can improve the nerve dysfunction.