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Your search keyword '"Iagafarova, Irina E."' showing total 2 results
Start Over Author "Iagafarova, Irina E." Topic carbenoids
2 results on '"Iagafarova, Irina E."'

1. RhIII-Catalyzed CF3-Carbenoid C-7 Functionalization of Indolines.

Author

Iagafarova, Irina E., Vorobyeva, Daria V., Loginov, Dmitry A., Peregudov, Alexander S., and Osipov, Sergey N.

Subjects
*INDOLINE, *CHELATION, *CHEMICAL reactions, *CARBOXYLATES, *CATALYSIS
Abstract

An efficient method for the CF3-carbenoid C-7 functionalization of N-pyrimidylindolines has been developed. This protocol uses readily available methyl 3,3,3-trifluoro-2-diazopropionate as a cross-coupling partner and smoothly proceeds under chelation-controlled RhIII catalysis. The reactions provide the indoline products with high regioselectivity within a few hours and allow for the introduction of both the CF3 and carboxylate functions at the C-7 position. [ABSTRACT FROM AUTHOR]

Published
2017
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2. CF3-Carbenoid C-H Functionalization of (Hetero)arenes under Chelation-Controlled RhIII Catalysis.

Author

Iagafarova, Irina E., Vorobyeva, Daria V., Peregudov, Alexander S., and Osipov, Sergey N.

Subjects
*TRIFLUOROMETHYL compounds, *CARBON-hydrogen bonds, *BENZENE, *INDOLE, *PROPIONATES, *CATALYSIS, *RHODIUM catalysts, *REGIOSELECTIVITY (Chemistry)
Abstract

An efficient method for the CF3-carbenoid C-H functionalization of benzenes and indoles using readily available methyl 3,3,3-trifluoro-2-diazopropionate as a cross-coupling partner under chelation-controlled RhIII catalysis has been developed. The reactions proceeded smoothly with high regioselectivity in a few hours and allowed the simultaneous introduction of CF3 and carboxylate functions into the 2-position of directing-group-containing benzenes and indoles. [ABSTRACT FROM AUTHOR]

Published
2015
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