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A new tandem process is reported that provides access to α- hydroxyamides from epoxides for the first time. Herein, we explore InCl3-mediated tandem rearrangement of epoxides to aldehydes and α-addition of TosMIC to in situ derived aldehydes. An unprecedented C-C bond-forming reaction is disclosed that features mild conditions, high yields, and shorter reaction times. [ABSTRACT FROM AUTHOR]

A convenient Pd(II)-catalyzed direct olefination of unactivated arenes with allylic esters and ethers via C-H activation was demonstrated. Under the typical conditions, various aryl-substituted allylic esters and ethers can be prepared. [ABSTRACT FROM AUTHOR]

An unprecedented base-promoted alkylation of easily accessible heterocyclic N-oxides using 1,1-diborylalkanes as alkyl source is reported. [ABSTRACT FROM AUTHOR]

The PCYP-catalyzed decarboxylative cross-coupling of chlorides (I), (IV), and (VIII) with 3-substituted propiolic acids (II) gives rise to unsymmetrically disubstituted alkynes (III), (V), and (IX) in high yields. [ABSTRACT FROM AUTHOR]

The scalable method represents the first catalytic procedure for the 1,4 over 1,2-selective conjugate allylation of aryl as well as alkyl substituted α,β-unsaturated aldehydes. [ABSTRACT FROM AUTHOR]

A metal- and oxidant-free trifluoromethylation of unactivated arenes and heteroarenes under either ultraviolet or visible light irradiation is presented. [ABSTRACT FROM AUTHOR]

Heterocyclic amines and diamine (Ib) are successfully arylated under atmospheric conditions in the presence of an inexpensive base. [ABSTRACT FROM AUTHOR]

An efficient, convenient, and environmentally benign protocol for preparation of various polysubstituted pyridines under mild reaction conditions is described. [ABSTRACT FROM AUTHOR]

Review: 460 refs. [ABSTRACT FROM AUTHOR]

A new benzyne transformation is described that affords versatile biaryl structures without using any transition-metal catalysts or organometallic building blocks. [ABSTRACT FROM AUTHOR]

Noteworthy, the catalysis succeeds in the high yield production of sterically encumbered tri-ortho-substituted biaryls (VI). [ABSTRACT FROM AUTHOR]

An unprecedented NHC-catalyzed bis-alkylation of N,N,N-tridentate chelating molecules is developed. [ABSTRACT FROM AUTHOR]

Review: 377 refs. [ABSTRACT FROM AUTHOR]

Isatin reacts with alkyl and aryl Grignard reagents to form 3-substituted 3-hydroxyoxindoles which are subsequently transformed with various nucleophiles, including allylstannane, thiophenol, indole, acetophenone enol trimethylsilylether and dimethyl malonate. [ABSTRACT FROM AUTHOR]

The synthesis of various allylic zinc pivalates with excellent thermal stability, ranging from several month to more than two years, is described. [ABSTRACT FROM AUTHOR]

(S,S)-3,4,5-Trifluorophenyl-NAS bromide is applied as an efficient phase-transfer catalyst for the enantioselective α-alkylation of orthogonally protected malonates (I). [ABSTRACT FROM AUTHOR]

A new Mycobacterium carboxylic acid reductase is found to catalyze the reduction of aliphatic and aromatic carboxylic acids leading to the corresponding aldehydes. [ABSTRACT FROM AUTHOR]

A copper-mediated synthesis of trifluorostyrene derivatives is developed. [ABSTRACT FROM AUTHOR]

Selective oxovanadium(V)-induced cross-coupling between boron and silyl enolates yields unsymmetrical 1,4-diketones. [ABSTRACT FROM AUTHOR]

Benzo[g]indole derivatives [(IV), (V), (VI), and (IX)] are synthesized starting from bis(dimethylamino)naphthalene derivative (I) through base-promoted transformation via pyrrole ring closure. [ABSTRACT FROM AUTHOR]

This unusual dimerization of substrates (I) proceeds via a dehydrohalogenation/1,6-conjugate addition/aromatization sequence. [ABSTRACT FROM AUTHOR]

The nickel-based catalytic system performs a Negishi-type cross-coupling of aryl chlorides with equimolar arylzinc chlorides, demonstrating that strongly electron donating diphosphine ligands are excellent ligands for this process. [ABSTRACT FROM AUTHOR]

A novel magnetic nanoparticle-supported oxime palladacycle catalyst is successfully prepared and characterized. [ABSTRACT FROM AUTHOR]

A wide range of bis(trimethylsilyl)methyl (BTSM)-substituted heteroaryl derivatives is prepared by using Kumada-Corriu or Negishi cross-coupling reactions. [ABSTRACT FROM AUTHOR]

Review: [28 refs. [ABSTRACT FROM AUTHOR]

Review: 101 refs. [ABSTRACT FROM AUTHOR]

involving a Pd-catalyzed cyclization to the indole framework as key reaction [ABSTRACT FROM AUTHOR]

The presented method represents the first example for the preparation of diarylketones via radical-radical cross coupling. [ABSTRACT FROM AUTHOR]

The catalytic activity of the newly synthesized catalyst is evaluated for the synthesis of tertiary butyl esters via tert-butoxycarbonylation of boronic acid derivatives. [ABSTRACT FROM AUTHOR]

Four-membered heterocyclic ketones undergo cross-ketal reactions with ketones (II) and (IV) as well as cross-aldol reactions with aldehydes (VI) and ketones (Ib,c) to give β-hydroxyketone derivatives. [ABSTRACT FROM AUTHOR]

affording alkynylated quinoline derivatives [ABSTRACT FROM AUTHOR]

Using benzyl methyl carbonates as substrate, a series of α-branched aldehydes is benzylated. [ABSTRACT FROM AUTHOR]

Various chalcones are synthesized from arenes and ketone Mannich bases involving a C-N cleavage. [ABSTRACT FROM AUTHOR]

A novel synthesis of skipped dienes having a cycloalkene moiety is accomplished by coupling of monosubstituted olefins with titanocene cycloalkenylidenes, generated in situ from compounds (I) or (IV) and Ti(Cp)2(P(O-Et)3)2. [ABSTRACT FROM AUTHOR]

Review: 80 refs. [ABSTRACT FROM AUTHOR]

Newly prepared binuclear organic antimony sulfonates prove to be efficient catalysts for Michael addition reaction of indoles with Michael acceptors as well as for allylation of aldehydes. [ABSTRACT FROM AUTHOR]

Using disubstituted alkynes instead of terminal alkynes, the formation of the title bisindole derivatives is not observed. [ABSTRACT FROM AUTHOR]

A variety of aromatic and aliphatic aldehydes are difluoroallylated by the title difluoroalkene (I) leading to fluorinated methylenealkanols (III) in good to excellent yields. [ABSTRACT FROM AUTHOR]

using dimethylsulfoxonium methylide [ABSTRACT FROM AUTHOR]

The method is highly enantio- and diastereoselective and affords less accessible 3-aminooxindoles with vicinal tetrasubstituted stereocenters. [ABSTRACT FROM AUTHOR]

Diastereoselective quaternization of ortho-sulfinylbenzyl-methylpropargylic carbanions is carried out with various allylic, propargylic, and benzylic halides. [ABSTRACT FROM AUTHOR]

Fluorinated products are obtained by a simple and mild carbene-catalyzed pentafluorophenylation (III) and dual tetrafluorophenylation (V) of aldehydes (I). [ABSTRACT FROM AUTHOR]

Review: [developments since 2011; 50 refs. [ABSTRACT FROM AUTHOR]

Dihalomethyl sulfoximes (V), (VII), and (X) are prepared and employed as dihalomethylation reagents for indanone (XI). [ABSTRACT FROM AUTHOR]

The title compounds are prepared either by a Suzuki-Miyaura protocol or by a Duff diformylation. [ABSTRACT FROM AUTHOR]

Various biaryls are efficiently obtained by radical cross-coupling reaction between unactivated benzene (II) and aryl iodides via homolytic aromatic substitution. [ABSTRACT FROM AUTHOR]

A variety of 2,3-diiodinated biphenyls and iodinated meta-terphenyls are synthesized by a regioselective Suzuki-Miyaura cross-coupling reaction of 1,2,3-triiodobenzenes. [ABSTRACT FROM AUTHOR]

A direct palladium-catalyzed C-H arylation to synthesize biaryls from dicyanobenzenes is presented. [ABSTRACT FROM AUTHOR]

Three component condensation of 1,3-diaryl-2-propen-1-ones with ethyl nitroacetate and ammonium acetate provides a convenient synthesis of 4,6-diarylated pyridin-2(1H)-ones. [ABSTRACT FROM AUTHOR]

under cobalt catalysis [ABSTRACT FROM AUTHOR]