ChemInform Abstract: Catalytic Asymmetric Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Linear α-Substituted Monothiomalonates with Isatin N-Boc Ketimines.

Authors :: Liu, Teng
Liu, Weiwei
Li, Xiaonian
Peng, Fangzhi
Shao, Zhihui
Source :: ChemInform. Oct2015, Vol. 46 Issue 40, pno-no. 1p.
Publication Year :: 2015
Abstract: The method is highly enantio- and diastereoselective and affords less accessible 3-aminooxindoles with vicinal tetrasubstituted stereocenters. [ABSTRACT FROM AUTHOR]

Subjects :: *MANNICH reaction
*MALONATES
*INDOLE derivatives
*ISOINDOLE
*ADDITION reactions
*CARBON-carbon bonds synthesis

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