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1. High-Performance Continuous Arteriovenous Hemofiltration in Infants with the New Minifilter Plus

Author

P A Conz, Mariano Feriani, M. Milan, Carlo Crepaldi, C. Ronco, Alessandra Brendolan, Luisa Bragantini, Roberto Dell'Aquila, G. La Greca, and Stefano Chiaramonte

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Internal medicine, Hemofiltration, medicine, Acute kidney injury, Cardiology, Continuous Arteriovenous Hemofiltration, medicine.disease, business, Continuous hemofiltration
Published
2015

2. Backfiltration in Clinical Dialysis

Author

G. La Greca, Mariano Feriani, Stefano Chiaramonte, Roberto Dell'Aquila, P A Conz, C. Ronco, M. Milan, Alessandra Brendolan, and Luisa Bragantini

Subjects
medicine.medical_specialty, business.industry, medicine, Intensive care medicine, Dialysis (biochemistry), business
Published
2015

3. Subject Index Vol. 91, 2002

Author

Hiroyuki Sasamura, Olaf Hergesell, K. Tabei, Osamu Hotta, Norio Sunagawa, Ioannis Tzanakis, Emanuela Rizzioli, Mingcai Qiu, Paul F. Laflam, Gian Marco Ghiggeri, Yasufumi Kyuden, D. Ljubanovic, M.J. Nubé, W.E.M. Schouten, Carla Carasi, Joachim Lundahl, Mariko Miyazaki, Isao Ishikawa, Yasuhiko Ueda, Kazuhiko Funabiki, Michael Nomikos, Tatsuo Kobayashi, Maria Magalhães, Manabu Asano, Takayuki Fujita, Shaul M. Shasha, Revital Shurtz-Swirski, Susana Sampaio, H. Furuya, Kefaia El-Sayed Mohamed, Mitsuhiro Satoh, A. Bihorac, Ç. Özener, Renza Cristofani, Ikue Mori-Kudo, U. Assogba, Satoshi Ogata, A.J. van Houte, Shifra Sela, Hidetake Kurihara, Maria Rita Metelli, Kayoko Nomura, Giovanni Montini, Atsushi Satomura, S. Krizanac, Rodo O. von Vigier, Morito Endo, Jürgen Floege, Lara Alonso da Silva, Yasuharu Nomura, Satoko Honda, Manuel Pestana, Hassan Abd-El-Hady Ahmed, Omar da Rosa Santos, P. Cacoub, Toshihiro Shinosaki, Ikuko Miyai, Y. Asano, Yoshiharu Nishitani, Yoshio Taguma, Chien-Liang Chen, Chizuru Ishiguro, P. Xavier, Gianluca Caridi, Marina Martic, Jean-Pierre Guignard, Maura Zanolari Calderari, Akira Saito, Hua-Chang Fang, F. A. W. Kemperman, Huiqi Qu, Atsushi Yamauchi, Hisaya Tada, Gavin J. Becker, Koji Harada, Mohamed Abel-Kader Sobh, Galal Mohamed Amer, Luisa Murer, P A Conz, Hiroyuki Ohi, Ali Moshfegh, Armando A. Mendes, Osama Gheith, Daisuke Suzuki, Fatma Elhusseini, Ciro Tetta, Eugênio Pacelle Queiroz Madeira, Yoshinobu Fuke, Takashi Uzu, Kang-Ju Chou, Savvas Kazoulis, Manuel Palacín, Ioannis Christoulakis, P. Hausfater, G. Kantarcı, Hideyuki Kurioka, Ivano Moschèn, Stefan H. Jacobson, Graziella Zacchello, Satoshi Horikoshi, Atsushi Tsuchida, Ryoko Shimizu-Hirota, Petros Hatzilias, Alberto Bettinelli, Tim D. Hewitson, Raymond T. Krediet, J.C. Piette, Jacek Borawski, S. Tokay, Takafumi Ito, Mutsuo Taiji, Ronit Geron, Makoto Watanabe, M. Schoorl, Carlo Catalano, Pia Thylén, Péter Tóth-Heyn, Ching-Bun Chen, Rajiv Kumar, Shigemi Chiba, Stefan Bröer, Takao Saruta, Mahmoud El-Baz, Yuji Fujita, E. Akoğlu, Roberto Palla, Michał Myśliwiec, Toshiki Inokuchi, Yasuhiko Tomino, Yasuhiro Akai, E. Kusano, Yukiteru Asakimori, Maria Norpoth, Shih-Yuan Hung, Yee-Hsuan Chiou, Kristen J. Kelynack, Hideo Shiiki, Alberto A.E. Bertelli, Mari Kuroda, Yoshihiko Taniguchi, Kazumasa Hamano, Massimiliano Migliori, Steven McTaggart, P. Lebon, Toshio Miyata, Vincenzo Panichi, Gunilla Halldén, Soichi Haraguchi, Mario G. Bianchetti, Po-Tsang Lee, M.P.C. Grooteman, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Yutaka Yaguchi, Florian Lang, Anna Maria Bianchi, Birgit Kallinowski, Mitchell L. Halperin, M. Inoue, Mizuo Mifune, Masayuki Iwano, Masafumi Yamato, Stefano De Pietro, Hiroshi Noguchi, Koji Kuboki, Hsiao-Min Chung, Hideto Sakai, Tomokazu Nagano, Iwan Setiawan, Surinder Cheema-Dhadli, Nobuoki Kohno, Shan Lin, M. Vrkljan, Isao Shirato, Noriaki Yorioka, Adriana MacIntyre Innocenzi, Marcella Normanno, José Gerardo Oliveira, Matsuhiko Hayashi, Y. Ando, Lambertus Arisz, Krystyna Pawlak, Galina Shapiro, Ikuo Horigome, Takashi Furuta, Y. Akai, Batya Kristal, João Ramos, Mahmoud Wageh Rasem, Alexandra Albers, Sarantos Xirakis, Sérgio Fernando Ferreira Santos, Takao Kawamura, Martin Zeier, Hiroo Noshiro, Manuela Della Vella, Daniele Taccola, Isao Ohsawa, K. Galesic, Mie Ko, Sana Sayed Gazarin, Eduardo H. Garin, Guilherme Santoro-Lopes, Mutsuko Hidaka, Luca Giovannini, and Giulietta Sbragia

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
2002

4. Contents Vol. 91, 2002

Author

Steven McTaggart, Hisaya Tada, D. Ljubanovic, Gunilla Halldén, M.J. Nubé, Marina Martic, Yasufumi Kyuden, Luisa Murer, Vincenzo Panichi, W.E.M. Schouten, Eugênio Pacelle Queiroz Madeira, Mariko Miyazaki, Yasuhiko Ueda, Hidetake Kurihara, Maria Norpoth, Guilherme Santoro-Lopes, Mutsuko Hidaka, Galal Mohamed Amer, Ali Moshfegh, Carlo Catalano, Chien-Liang Chen, Stefano De Pietro, Koji Kuboki, Ryoko Shimizu-Hirota, P. Hausfater, Susana Sampaio, Yoshinobu Fuke, Manuel Palacín, Luca Giovannini, Savvas Kazoulis, Satoshi Ogata, A.J. van Houte, Ikuo Horigome, Graziella Zacchello, Alberto Bettinelli, Batya Kristal, Tim D. Hewitson, Isao Shirato, Noriaki Yorioka, Makoto Watanabe, Renza Cristofani, Sérgio Fernando Ferreira Santos, Takao Kawamura, Y. Akai, S. Krizanac, Jacek Borawski, Maura Zanolari Calderari, Nobuoki Kohno, Marcella Normanno, Giulietta Sbragia, Iwan Setiawan, U. Assogba, Mitsuhiro Satoh, Mutsuo Taiji, Y. Asano, Mahmoud El-Baz, Daisuke Suzuki, Gavin J. Becker, Akira Saito, Giovanni Montini, Stefan Bröer, Yuji Fujita, Revital Shurtz-Swirski, Paul F. Laflam, P A Conz, Ching-Bun Chen, Ioannis Christoulakis, Toshihiro Shinosaki, Takafumi Ito, Takashi Uzu, Yasuhiro Akai, Kang-Ju Chou, G. Kantarcı, Shan Lin, Atsushi Tsuchida, Hideo Shiiki, Mari Kuroda, Atsushi Satomura, Huiqi Qu, Soichi Haraguchi, Michał Myśliwiec, Masayuki Iwano, Masafumi Yamato, M. Vrkljan, Petros Hatzilias, Yoshihiko Taniguchi, Atsushi Yamauchi, Emanuela Rizzioli, Mingcai Qiu, Mohamed Abel-Kader Sobh, Sana Sayed Gazarin, Shigemi Chiba, M. Schoorl, E. Kusano, Yukiteru Asakimori, Anna Maria Bianchi, Birgit Kallinowski, Mario G. Bianchetti, Armando A. Mendes, Yutaka Yaguchi, Isao Ishikawa, Manuel Pestana, Pia Thylén, M. Inoue, Shifra Sela, Po-Tsang Lee, Massimiliano Migliori, Jean-Pierre Guignard, Olaf Hergesell, P. Lebon, Hideto Sakai, Yee-Hsuan Chiou, Kristen J. Kelynack, Alberto A.E. Bertelli, Osamu Hotta, Shaul M. Shasha, Tomokazu Nagano, Lambertus Arisz, Martin Zeier, H. Furuya, Kefaia El-Sayed Mohamed, A. Bihorac, Ç. Özener, Lara Alonso da Silva, Hiroshi Noguchi, Toshio Miyata, Takao Saruta, E. Akoğlu, Stefan H. Jacobson, Krystyna Pawlak, Ivano Moschèn, Maria Rita Metelli, Hsiao-Min Chung, Takashi Furuta, Adriana MacIntyre Innocenzi, Yoshiharu Nishitani, Kazumasa Hamano, Manabu Asano, Mizuo Mifune, Kayoko Nomura, Tatsuo Kobayashi, Gian Marco Ghiggeri, João Ramos, Mahmoud Wageh Rasem, José Gerardo Oliveira, Hassan Abd-El-Hady Ahmed, Hiroyuki Ohi, S. Tokay, Matsuhiko Hayashi, Osama Gheith, Carla Carasi, P. Xavier, Ikue Mori-Kudo, Hiroo Noshiro, Kazuhiko Funabiki, Michael Nomikos, Chizuru Ishiguro, Ikuko Miyai, Maria Magalhães, Péter Tóth-Heyn, Satoko Honda, Manuela Della Vella, Daniele Taccola, Gianluca Caridi, Yasuharu Nomura, Hideyuki Kurioka, Joachim Lundahl, P. Cacoub, Y. Ando, Ronit Geron, Toshiki Inokuchi, Eduardo H. Garin, Galina Shapiro, Roberto Palla, Shih-Yuan Hung, Yasuhiko Tomino, Ciro Tetta, Surinder Cheema-Dhadli, Alexandra Albers, Sarantos Xirakis, Florian Lang, Mitchell L. Halperin, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Jürgen Floege, Yoshio Taguma, Koji Harada, Hua-Chang Fang, F. A. W. Kemperman, Satoshi Horikoshi, Rodo O. von Vigier, Morito Endo, Omar da Rosa Santos, Norio Sunagawa, M.P.C. Grooteman, Fatma Elhusseini, Takayuki Fujita, Raymond T. Krediet, J.C. Piette, Rajiv Kumar, Hiroyuki Sasamura, K. Tabei, Ioannis Tzanakis, K. Galesic, Mie Ko, and Isao Ohsawa

Subjects
Traditional medicine, business.industry, Medicine, business
Published
2002

5. Contents Vol. 86, 2000

Author

Okan Bakınen, Gilbert Deray, Ken Okumura, Keiko Uchida, Ljubica Ðukanović, J.H. Park, Y.S. Haviv, Mitsuyoshi Furuhashi, Shou-Shan Chiang, Vladisav Stefanovic, Martin Ellbogen, E. Sedano, L. Grcevska, Sun Ae Yoon, Yuet-Ching Tay, Junne-Ming Sung, Hirotsugu Iwatani, Matt Koch, Toshiyuki Imasawa, Michael Field, Masahiko Nakamoto, Vincenzo Bellizzi, Jung-Kuei Pai, H. Pasantes-Morales, Yoshiyuki Hiki, Robert Dunlay, Yoshiaki Takemoto, Hideaki Yamabe, Johan W. de Fijter, Yutaka Kobayashi, Junko Tanaka, Ayşegül Örs Zümrütdal, Jyh-Gang Leu, B.K. Bang, Katsuo Suyama, Shigetake Sasayama, J. Möcks, A. Rodríguez-Cuartero, Toshika Okumiya, Minako Koike, Byung Kee Bang, Naoyuki Tamura, Hacı Veli Atalay, Adriaan M. Kamper, I. Villen, Chie Tomida, Heather J. Saunders, Kenji Tsuchida, Akira Kawashima, Giuseppe La Greca, Ming-Cheng Wang, Shu-May Lin, Tetuhiko Yoshida, Qu Huiqi, Yukitaka Maruyama, Hiroshi Nihei, Michihiro Gotoh, Kazuho Honda, Yasukazu Yamada, Shinichi Kakumu, Sohji Nagase, Elsie-C. Chan, Mutsuko Hidaka, Atsushi Ueda, Aysun Karabay Bayazit, Kazumasa Aoyagi, Masaya Yamato, Akio Koyama, Yoshihiro Matsumoto, Diana Ionova, Wei-Chi Lee, Slavenka Janković, Hiroshi Osawa, Tatsuo Hosoya, Qiu Mingcai, Takako Takita, Lin Shan, Shu-Yin Kuo, Gopala K. Rangan, Tsung Hsiu Wang, Richard J. Lund, Tatsuya Nakatani, Harutaka Yamada, Krasimira Sepetlieva, M. Pérez-Suarez, Jerome G. Porush, Aytül Noyan, Stefan Fründ, Predrag Vlahović, Weier Qi, P A Conz, Akihiko Kato, Hui Kyung Jeon, Jelena Marinkovic, Kazuhiro Okano, Akira Hishida, J.Y. Choi, Krystyna Szprynger, Brad Oldemeyer, Satoru Tsunoda, Takayuki Fujita, Hatice Bodur, G. Petruševska, Isao Ohsawa, Danuta Zwolińska, York Leng Yu, Arao Futenma, Hitoe Suzuki, G. Maschio, J.L. Pérez-Castrillón, Rich Jones, Gakusen Nishihara, Takanari Aoki, Maria Szczepańska, Danica Bukvić, Sumio Tateno, Masahiro Kakihara, M. Milovanceva-Popovska, Young Ok Kim, Kuddusi Cengiz, M. Arrabal-Martín, Yau-Huei Wei, Tein-Chung Lu, Toshiyuki Takahashi, David A. Vesey, Hiroshi Tatsumi, Kamen Tcachev, Keisuke Yamamoto, Eriya Kikawada, Monika Bulla, Vincenzo Terracciano, Jeng-Jong Huang, Haruo Tomonari, Junji Terao, Halil Uçan, Atsushi Fukatsu, Atsushi Yamauchi, Sun Jeong Lim, Robert Kleta, Kosaku Nitta, Atsushi Satomura, A. Zuluaga, Yoshiko Baba, Morito Endo, F.J. Pérez-Blanco, Hassan Izzedine, Paik-Seong Lim, M. Polenakovic, Mitsuaki Kaizuka, C.W. Yang, Takashi Uzu, A. Egon van der Bijl, Biagio Di Iorio, Chikao Yasunaga, Fumiko Tateyama, Aya Abe, Yiping Wang, Eun Jung Jun, Chan Joo Kim, Chang Hee Han, Ali Anarat, Eri Muso, Satoru Kuriyama, Izumi Amano, Aki Hirayama, Takanobu Sakemi, Y.M. Choo, Wey-Wen Jiang, G.B. Kim, Fen-Fen Chen, S. Morales Mulia, Anna Medyńska, Marina Mitić-Zlatković, Wako Yumura, I. Justo-Muradas, Carlo Crepaldi, Koichi Suzuki, Yasuhiro Chikamori, Kenichi Shirato, Naoto Miura, Y.S. Kim, Katsumi Takemura, Leendert C. Paul, Carol A. Pollock, A.J. Meares, Masatomo Yashiro, Vincent Launay-Vacher, Hiroyuki Ohi, David W. Johnson, E. Saracibar, David Harris, and Eberhard Kuwertz-Bröking

Subjects
Traditional medicine, business.industry, Medicine, business
Published
2000

6. Integration of Peritoneal Dialysis in Active Uremia Treatment

Author

F. Gastaldon, P A Conz, Carlo Crepaldi, Luisa Bragantini, G La Greca, Roberto Dell'Aquila, D. Dissegna, and C. Ronco

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Urology, General Medicine, medicine.disease, Uremia, Peritoneal dialysis, Compliance (physiology), Nephrology, Medicine, Renal replacement therapy, Hemodialysis, business
Published
1996

7. The Concept of Adequacy in Peritoneal Dialysis

Author

P A Conz, S Q Lew, F. Agostini, C. Ronco, G La Greca, and J P Bosch

Subjects
medicine.medical_specialty, Rehabilitation, Dry body weight, business.industry, medicine.medical_treatment, 030232 urology & nephrology, Blood purification, General Medicine, 030204 cardiovascular system & hematology, Surgery, Peritoneal dialysis, 03 medical and health sciences, 0302 clinical medicine, Nephrology, Kt/V, Medicine, Renal replacement therapy, Dialisis peritoneal, business, Blood urea nitrogen
Abstract

The aim of renal replacement therapy is to obtain blood purification from metabolic waste products sufficient to achieve patient rehabilitation, the control of dry body weight, and the correction of acid base and electrolyte imbalances (1–3). Among these, the correction of the hormonal imbalances as a result of renal disease would also be required (4). However, this is difficult to achieve, and the majority of substitute therapies such as hemodialysis and peritoneal dialysis focus on blood purification and fluid and electrolyte homeostasis. For this reason the search for the optimal dialytic therapy has been limited to the possibility of achieving a treatment that could at least be adequate in terms of blood purification and patient rehabilitation. Therefore, dialysis adequacy has been selected as a term to indicate successful renal replacement therapy, one that could overcome most of the uremic symptoms and allow the patient to reach a sufficient degree of rehabilitation, even though the treatment is far from the complete and optimal substitution of the lost kidney function in its whole. In recent years the concept of dialysis adequacy has been studied by several authors, and a continuous evolution of this concept has been observed. From the original description of the square-meter-hour hypothesis of Babb and Scribner in 1971 (5), a series of new studies led to the clinical application of various indices devoted to describing the level of efficiency achieved by dialysis treatment (6,7). Finally, after the American National Cooperative Dialysis Study was analyzed, and the KTN index was selected as a marker for dialysis adequacy, the majority of authors now rely on this index and are proposing various formulas for its calculation (8–11).

Published
1994

8. Ash Split Cath® in Geriatric Dialyzed Patients

Author

M Normanno, E. Rizzioli, Fabio Fabbian, P A Conz, G Preciso, and C Catalano

Subjects
medicine.medical_specialty, medicine.medical_treatment, Fistula, Population, 030232 urology & nephrology, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, 030204 cardiovascular system & hematology, Geriatric patient, Hemodialysis, Tunnelled catheter, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, medicine, education, Dialysis, education.field_of_study, Venous pressure, business.industry, General Medicine, Blood flow, medicine.disease, Surgery, Catheter, Venous thrombosis, business
Abstract

Vascular access is the essential step in performing hemodialysis in uremic patients. In the absence of a permanent and utilizable native arterio-venous fistula, the use of a tunnelled catheter makes dialysis therapy possible. The Ash Split Cath, a recently introduced chronic hemodialysis catheter, was inserted in five patients (7.1 % of our prevalent dialysis population) because of repeated venous thrombosis in three patients and a poor venous tree in two. The mean age of patients was 78 years ± 7. The average blood flow rate was 250 ± 50 ml/minute and the mean venous pressure 140mm Hg ± 35. Recirculation determined by low flux technique was less than 2 %. KT/V calculated 3 months after the catheter placement was 1.2 ± 0.02. During the follow-up we did not document any infection of the exit site or related to the catheter. This device is simple to place, gives adequate dialysis treatment and is useful in geriatric dialyzed patients in whom the arterio-venous fistula can no longer be used.

Published
2001

9. Vascular Calcification of the Venous Side of an Arterious-Venous Fistula

Author

F. Fabbian, C. Catalano, L. Davì, M. Normanno, E. Rizzioli, and P. A. Conz

Subjects
medicine.medical_specialty, arteriovenous fistula, calcification (complication, diagnosis, etiology), vein calcification (complication, business.industry, Fistula, Vascular Calcifications, medicine.disease, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Nephrology, Medicine, Surgery, Radiology, business, Vascular calcification, Calcification
Abstract

While reports of venous calcifications are scarce, vascular calcifications frequently occur in the arteries of uraemic patients. Venous calcification of an aged arterious-venous (a-v) fistula in a young patient with a long-standing history of hyperparathyroidism was detected on a forearm X-ray. Risk factors for vascular calcifications are still under debate, but calcium-phosphate product appears to be involved in its pathogenesis. We suggest that a-v fistula of patients with hyperparathyroidism history should be monitored as calcifications could be a risk factor for access thrombosis.

Published
2001

10. Alpha-1-Antichymotrypsin in Renal Biopsies

Author

P A Conz, P A Bevilacqua, Mariano Feriani, C. Ronco, S. Meli, Alessandra Brendolan, G. Pietribiasi, G. La Greca, and Roberto Dell'Aquila

Subjects
Pathology, medicine.medical_specialty, alpha 1-Antichymotrypsin, Renal glomerulus, Biopsy, Kidney Glomerulus, Alpha (ethology), Monocytes, Alpha 1-antichymotrypsin, Nephropathy, medicine, Humans, Kidney, biology, medicine.diagnostic_test, business.industry, Macrophages, Proteolytic enzymes, medicine.disease, medicine.anatomical_structure, alpha 1-Antitrypsin, biology.protein, Immunohistochemistry, Kidney Diseases, Renal biopsy, business, Biomarkers
Abstract

Alpha 1-Antichymotrypsin (alpha 1-AK) and alpha-1-antitrypsin (alpha 1-AT) represent a defense mechanism to protect the tissues from proteolytic enzyme activity. We studied the implication of alpha 1-AK and alpha 1-AT in glomeruli of patients with different nephropathies based on the analysis of 52 paraffin-embedded renal biopsies with alpha 1-AK and alpha 1-AT antisera. The results demonstrate an intense alpha 1-AK glomerular staining in renal biopsies from patients with minimal-change disease, while a minor staining of this protein was found in the other nephropathies. No significant evidence of alpha 1-AT deposits was observed in our cases. Our findings suggest that when alpha 1-AK is lacking in glomeruli the defense mechanisms against proteolytic enzymes may not be efficient enough to protect the glomerular structures and limit the damage. Since alpha 1-AK is a reactant of the acute phase of inflammation, it may be considered as a marker of activity for monocyte-macrophages in glomerular damage.

Published
1990

11. Slow maturation of arterio-venous fistula in seven uremic patients: use of Ash Split Cath(R) as temporary, prolonged vascular access

Author

G. La Greca, P A Conz, and Carlo Crepaldi

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, 030232 urology & nephrology, Vascular access, 030204 cardiovascular system & hematology, Arterio-venous fistula, Surgery, 03 medical and health sciences, Catheter, 0302 clinical medicine, medicine.anatomical_structure, Nephrology, Cuff, medicine, Hemodialysis, Vein, business, Internal jugular vein, Dialysis
Abstract

The temporary vascular access is the essential condition required to perfrom hemodialysis in uremic patients in the absence of a permanent and utilizable vascular access. The cannulation of a central vein with a dual lumen catheter may be useful when a few weeks are required for the maturation of AVF. Longer times for AVF maturation (such as in diabetic patients and in aged patients) impose the use of a tunnelled catheter such as Tesio Catheter or Hickman Catheter which lead to minor complications and more efficient dialysis treatment. The Ash Split Cath®, a recently introduced chronic hemodialysis catheter, provides dialysis via a transcutaneous portion containing a 14 French cylindrical shaped catheter with D-shaped lumens and a dacron cuff. Due to the slow maturing of AVF, in our Department the Ash Split Cath has been used in 7 uremic patients (3 males and 4 females) who required hemodialysis. The cannulation of the internal jugular vein was performed by an ultrasound assisted technique and the correct catheter position was verified by standard chest X-rays. The average blood flowrates were 250 ml/min, and the mean KT/V calculated in all patients one month after the beginning of the dialytic therapy was 1.09 ± 0.02. In six patients the catheter was utilized for at least 4 months, in one patient for 8 months. The devices were easily removed when the patient's AVF was functional and usable. We found that the use of the Ash Split Cath as a temporary, prolonged vascular access in uremic patients was optimal allowing for flexibility in organizing the dialysis treatment schedule and in yielding a good performance in the initial dialysis therapy. Moreover, this device allows, in these patients, a satisfactory dialysis efficiency.

Published
2007

12. Mid-Dilution: The Perfect Balance between Convection and Diffusion

Author

E. Rizzioli, Emiliana Ferramosca, Antonio Santoro, V. de Cristofaro, P A Conz, J.L. Renaux, R. Gaggi, Mary Lou Wratten, and Irene Acquistapace

Subjects
medicine.medical_specialty, Creatinine, integumentary system, business.industry, medicine.medical_treatment, Bicarbonate, Sodium, Urology, chemistry.chemical_element, Blood flow, Surgery, chemistry.chemical_compound, Ultrafiltration (renal), chemistry, medicine, Urea, Hemodialysis, business, Dialysis
Abstract

Although hemodiafiltration (HDF) offers the advantage of increased convective clearance for middle molecules, there is still controversy as to whether reinfusion should occur pre- or postfilter. Mid-dilution hemodiafiltration (MD HDF) is a new HDF technique that uses a special dialyzer, MD190, which allows both pre- and postreinfusion. While externally the dialyzer looks similar to conventional hemodialyzers, the internal fibers are divided into two bundles by a special annular header that first lets the blood pass through the peripheral bundle in ‘postdilution’, mix with the reinfusion fluid at the opposite end of the dialyzer and then proceed (after ‘predilution’) to the dialyzer blood exit. The dialyzer is able to support substantially higher reinfusion rates (10-12 l/h). We have compared the removal characteristics of several small solutes and larger middle-molecular-weight toxins by examining instantaneous clearance at 45 min, the dialysis reduction ratio and total mass removal (by spilling) in a three-center prospective cross-over study. Twenty patients were randomized to a treatment sequence of one-week high-flux bicarbonate hemodialysis (HD) followed by MD HDF, or vice versa. The parameters evaluated included urea, creatinine, Β2-microglobulin, angiogenin, leptin, retinol-binding protein, and the effects on sodium, potassium, bicarbonate and calcium. Blood flow rates ranged between 300-450 ml/min (mean 359 ± 44 HD, 367 ± 35 MD HDF). The mean reinfusion for MD HDF was 166 ±17 ml/min. MD HDF had a significantly better instantaneous clearance for urea (328 ± 28 vs 277 ± 40); creatinine (292 ± 32 vs. 212 ± 66); phosphate (324 ± 38 vs. 242 ± 63); Β2-microglobulin (249 ± 27 vs. 100 ± 24); angiogenin (173 ± 27 vs. 28 ± 32); and leptin (202 ± 29 vs. 63 ± 43). Treatments were well tolerated with no adverse reactions occurring during any of the treatments. The MD HDF filter’s unique configuration is designed to deliver high-efficiency HDF with a significant improvement in small and middle molecule removal. MD HDF supports substantially higher ultrafiltration rates, and as such, results in a higher removal of middle-molecular-weight toxins.

Published
2005

13. Stomach phytobezoars in two uremic anorexic patients

Author

C Catalano, Fabio Fabbian, P A Conz, and L. Leone

Subjects
Hemodialysis patients, Male, medicine.medical_specialty, Population, Anorexia, Gastroenterology, Bezoars, Autonomic neuropathy, Phytobezoars, Internal medicine, medicine, Humans, education, Aged, Uremia, education.field_of_study, medicine.diagnostic_test, Gastric emptying, Esophagogastroduodenoscopy, business.industry, Stomach, digestive, oral, and skin physiology, medicine.disease, Surgery, medicine.anatomical_structure, Phytobezoar, Bezoar, medicine.symptom, business
Abstract

Conglomerates of food and mucus or phytobezoars composed of vegetable matter are sometimes found in the stomach in the general population. Reports of phytobezoars in uremic patients are, however, scarce. Here we describe 2 uremic patients in which esophagogastroduodenoscopy was performed due to dyspepsia associated with weight loss and in which stomach phytobezoars were discovered. Theoretically, uremic patients should be at risk for producing bezoars. In fact, these patients frequently present predisposing conditions such as autonomic neuropathy, diabetes mellitus and delayed gastric emptying. Gastric bezoars cause anorexia. Anorexia is a frequent symptom in dialysis patients and is associated with malnutrition. In these patients, malnutrition is strongly associated with mortality and is quite difficult to reverse. Similarly, phytobezoars cause chronic anorexia. We suggest that clinicians working in dialysis units should consider the possibility of a gastric bezoar when evaluating anorexic uremic patients.

Published
2002

14. TINU syndrome associated with reduced complement levels

Author

Luisa Bragantini, P A Bevilacqua, P A Conz, G. La Greca, and M. Milan

Subjects
CD4-Positive T-Lymphocytes, Pathology, medicine.medical_specialty, Biopsy, Tubulointerstitial nephritis and uveitis, CD8-Positive T-Lymphocytes, Uveitis, Immunopathology, medicine, Humans, Acute-Phase Reaction, Kidney, medicine.diagnostic_test, business.industry, Complement C4, Syndrome, Middle Aged, medicine.disease, medicine.anatomical_structure, Kidney Tubules, Immunology, Immunohistochemistry, Nephritis, Interstitial, Female, Renal biopsy, business, CD8, Kidney disease
Abstract

The TINU syndrome (tubulointerstitial nephritis and uveitis) was first described by Dobrin et al. in 1975. Since then, more than 50 cases have been documented each with diverse immunopathogenetic and genetic characteristics. The aim of this report is to describe a case of TINU associated with reduced complement levels. We profile a 48-year-old white female with persistently reduced C4 complement levels during the acute phase of the pathology and with an unaltered immunologic profile. Renal biopsy evidenced a significant lymphocytic interstitial infiltration. Immunohistochemical studies of the interstitium infiltrates was positive for the presence of the T (CD3) markers (CD4 > CD8). Steroid therapy yielded a complete regression of the symptomatology with normalization of the complement levels. We suggest that it is possible to hypothesize that the various immunologic alterations associated with TINU, including the transient reduction complement levels, may be secondary to multiple inflammatory mechanisms which express themselves throughout the pathology.

Published
2001

15. Catheter Tip Position: Outside the Atrium

Author

M Normanno, D Munaro, A. Malagoli, C. Bovo, P A Conz, and E. Rizzioli

Subjects
Catheter, medicine.anatomical_structure, Nephrology, business.industry, medicine, Surgery, Anatomy, Atrium (heart), business, Tip position
Published
2006

16. Assessment of adequacy in peritoneal dialysis

Author

Claudio Ronco, Giuseppe La Greca, P A Conz, Susy Q. Lew, and Juan P. Bosch

Subjects
Adult, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Urology, Renal function, Peritoneal dialysis, Blood Urea Nitrogen, chemistry.chemical_compound, Peritoneal Dialysis, Continuous Ambulatory, medicine, Humans, Urea, Prospective Studies, Blood urea nitrogen, Dialysis, Aged, Uremia, Creatinine, business.industry, Continuous ambulatory peritoneal dialysis, Middle Aged, medicine.disease, Surgery, Treatment Outcome, chemistry, Nephrology, Hemodialysis, Dietary Proteins, business, Mathematics
Abstract

Adequacy of peritoneal dialysis has been less well studied than that of hemodialysis. Fractional urea removal, total creatinine removal, and various indices have been proposed to reflect or predict patient morbidity and mortality. No prospective study has been published in this regard. To evaluate this area further, in addition to reviewing selected literature, 45 continuous ambulatory peritoneal dialysis (CAPD) patients were recruited in two dialysis centers for a prospective study on treatment adequacy. Patients were well rehabilitated and had no peritonitis or hospitalization in the 6 months before the study. Urea and creatinine kinetics were analyzed, as were dietary intake and fluid balance. The weekly Kt/V, calculated to include peritoneal and residual renal clearance (KprT/V), averaged 1.77 with a Kt/V hemodialysis equivalent of 0.59. Patients with residual renal function (58% of the studied population) had an average residual renal clearance of 3.42 mL/min, and had lower steady-state concentrations of urea nitrogen and creatinine in the plasma than patients with no residual renal function. As a consequence, a lower percent excretion of urea and creatinine in the peritoneal fluid was observed in the former patients compared with the latter, where the peritoneal route was the only one for solute excretion. The concentration profiles in blood appear to be the critical factor in achieving the final target of the treatment, ie, the excretion of the overall amount of waste products derived from protein and other metabolic pathways. The constant blood levels in CAPD explain why such a low Kt/V can be adequate whereas, in hemodialysis, a higher Kt/V is required.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1994

17. Evoluzione Delle Tecniche Dialitiche

Author

P A Conz and G. La Greca

Subjects
lcsh:Internal medicine, business.industry, Medicine, General Medicine, business, lcsh:RC31-1245, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923
Abstract

non disponibile

Published
1994

19. Beta-2-microglobulin and Helicobacter pylori infection in uraemic dialysed patients

Author

D. Bernardini, G. La Greca, P A Bevilacqua, P A Conz, S. Dante, and V. Bertoncello

Subjects
Adult, Male, medicine.medical_specialty, Chronic gastritis, Gastroenterology, Helicobacter Infections, Renal Dialysis, Internal medicine, Gastric mucosa, Medicine, Humans, Aged, Uremia, Hepatology, biology, Helicobacter pylori, business.industry, Beta-2 microglobulin, Middle Aged, medicine.disease, biology.organism_classification, Mucus, medicine.anatomical_structure, Gastritis, Chronic Disease, Immunohistochemistry, Female, medicine.symptom, business, beta 2-Microglobulin, Infiltration (medical)
Abstract

Chronic gastritis in patients with chronic renal failure may have different causes and mechanisms. Recent observations suggest that severe gastritis often found in uraemic patients might be related to Helicobacter pylori (HP) infection. In chronic gastritis HP has been found in the mucus and on the epithelial cell surface of gastric foveolas. Significant infiltration of the subepithelial gastric layer by polymorphonuclear leucocytes has been described. Moreover, beta-2-microglobulin deposits have been found by immunohistochemical methods in the subepithelial layer of gastric mucosa of uraemic dialysed patients with active chronic gastritis and HP infection. Similar findings have also been demonstrated in gastric biopsies from patients with HP positive active chronic gastritis and normal renal function. Since HP infection is associated with significant leucocyte infiltration, it is hypothesized that the inflammatory process causes the release of beta-2-M from the surface of the leucocytes and its subsequent deposition at gastric level.

Published
1992

21. Subject Index Vol. 86, 2000

Author

Junne-Ming Sung, V. Terracciano, Tatsuo Hosoya, Yutaka Kobayashi, Ken Okumura, Keiko Uchida, Tatsuya Nakatani, Krasimira Sepetlieva, L. Grcevska, G. Maschio, Ayşegül Örs Zümrütdal, Martin Ellbogen, H. Pasantes-Morales, Yoshiyuki Hiki, Robert Dunlay, Jung-Kuei Pai, Mitsuyoshi Furuhashi, Monika Bulla, Shou-Shan Chiang, Toshiyuki Imasawa, Vladisav Stefanovic, E. Sedano, Halil Uçan, J.L. Pérez-Castrillón, Takanari Aoki, Sumio Tateno, Eri Muso, Vincenzo Bellizzi, M. Polenakovic, M. Milovanceva-Popovska, B.K. Bang, Atsushi Fukatsu, Aysun Karabay Bayazit, Kuddusi Cengiz, Michael Field, M. Arrabal-Martín, Giuseppe La Greca, J.H. Park, I. Villen, Leendert C. Paul, Brad Oldemeyer, Rich Jones, M. Pérez-Suarez, Yukitaka Maruyama, Chie Tomida, Keisuke Yamamoto, Slavenka Janković, Kenji Tsuchida, Johan W. de Fijter, Byung Kee Bang, Harutaka Yamada, Hui Kyung Jeon, Jelena Marinkovic, Jerome G. Porush, Diana Ionova, Yasukazu Yamada, Stefan Fründ, Fumiko Tateyama, Sohji Nagase, Danuta Zwolińska, Y.S. Haviv, Shigetake Sasayama, Adriaan M. Kamper, Isao Ohsawa, Predrag Vlahović, Aki Hirayama, Sun Jeong Lim, Takanobu Sakemi, G. Petruševska, Elsie-C. Chan, Shinichi Kakumu, Yoshihiro Matsumoto, Shu-Yin Kuo, Haruo Tomonari, Robert Kleta, Y.M. Choo, Krystyna Szprynger, Masahiko Nakamoto, Matt Koch, Naoyuki Tamura, Heather J. Saunders, Satoru Tsunoda, Junko Tanaka, Shu-May Lin, Satoru Kuriyama, Izumi Amano, Hitoe Suzuki, Hiroshi Tatsumi, Danica Bukvić, Anna Medyńska, Gopala K. Rangan, Kazuhiro Okano, Tetuhiko Yoshida, Qu Huiqi, Biagio Di Iorio, Morito Endo, Atsushi Yamauchi, Tein-Chung Lu, Wei-Chi Lee, Qiu Mingcai, Maria Szczepańska, Akira Kawashima, Jyh-Gang Leu, J. Möcks, Richard J. Lund, Minako Koike, Mutsuko Hidaka, Mitsuaki Kaizuka, Hideaki Yamabe, Kazuho Honda, Akira Hishida, F.J. Pérez-Blanco, Hassan Izzedine, David A. Vesey, Wey-Wen Jiang, Michihiro Gotoh, Jeng-Jong Huang, G.B. Kim, Hacı Veli Atalay, Fen-Fen Chen, Toshiyuki Takahashi, Kosaku Nitta, Aytül Noyan, Yuet-Ching Tay, J.Y. Choi, P A Conz, Takayuki Fujita, Takako Takita, Lin Shan, Ming-Cheng Wang, Hiroshi Nihei, Tsung Hsiu Wang, C.W. Yang, Gilbert Deray, Young Ok Kim, Sun Ae Yoon, Takashi Uzu, Katsuo Suyama, Atsushi Satomura, Eriya Kikawada, Yau-Huei Wei, Chang Hee Han, Marina Mitić-Zlatković, Ali Anarat, Yoshiaki Takemoto, Ljubica Ðukanović, Hirotsugu Iwatani, Kamen Tcachev, York Leng Yu, Junji Terao, Yiping Wang, Kazumasa Aoyagi, Paik-Seong Lim, A. Zuluaga, Akio Koyama, Wako Yumura, Eun Jung Jun, Arao Futenma, A. Rodríguez-Cuartero, Toshika Okumiya, Atsushi Ueda, Hiroshi Osawa, Weier Qi, Akihiko Kato, Gakusen Nishihara, A. Egon van der Bijl, Yoshiko Baba, Chikao Yasunaga, Aya Abe, Chan Joo Kim, Okan Bakınen, I. Justo-Muradas, Masaya Yamato, Katsumi Takemura, Carlo Crepaldi, Carol A. Pollock, Koichi Suzuki, S. Morales Mulia, Yasuhiro Chikamori, Kenichi Shirato, Naoto Miura, Y.S. Kim, David Harris, Eberhard Kuwertz-Bröking, A.J. Meares, Masatomo Yashiro, Vincent Launay-Vacher, Hiroyuki Ohi, David W. Johnson, E. Saracibar, Hatice Bodur, and Masahiro Kakihara

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
2000

22. Impact of high blood flows on vascular stability in haemodialysis

Author

C. Ronco, Alessandra Brendolan, Stefano Chiaramonte, Mariano Feriani, G. Finocchi, G. La Greca, Luisa Bragantini, Roberto Dell'Aquila, P A Conz, B. Agazia, D. Dissegna, A. Fabris, E. De Dominicas, M. Milan, and Carlo Crepaldi

Subjects
Transplantation, medicine.medical_specialty, business.industry, medicine.medical_treatment, Cardiovascular System, Nephrology, Renal Dialysis, Internal medicine, medicine, Cardiology, Humans, Hemodialysis, Hypotension, business, Blood Flow Velocity
Published
1990

23. Pathophysiology of ultrafiltration in peritoneal dialysis

Author

Roberto Dell'Aquila, Stefano Chiaramonte, G La Greca, Luisa Bragantini, Mariano Feriani, M. Milan, C. Ronco, P A Conz, and Alessandra Brendolan

Subjects
medicine.medical_specialty, Membrane permeability, medicine.medical_treatment, 030232 urology & nephrology, Ultrafiltration, Urology, Peritonitis, Peritoneal equilibration test, Peritoneal dialysis, Capillary Permeability, 03 medical and health sciences, 0302 clinical medicine, Osmotic Pressure, Dialysis Solutions, medicine, Humans, business.industry, Reabsorption, Microcirculation, General Medicine, Blood flow, Water-Electrolyte Balance, medicine.disease, Surgery, Catheter, Nephrology, 030211 gastroenterology & hepatology, Peritoneum, business, Peritoneal Dialysis, Algorithms
Abstract

Pathophysiology of peritoneal ultrafiltration is analyzed in the present study. Peritoneal equilibration test is the easiest procedure to study in detail the possible causes of failure to control the ultrafiltration rate in patients undergoing peritoneal dialysis. Membrane failure, reduction in peritoneal blood flow, excessive lymphatic reabsorption catheter malposition, and fluid sequestration are the most common causes of ultrafiltration loss. Pharmacologic manipulation of peritoneal membrane, correction of mechanical inconvenients, reduction in peritonitis rate and in the level of immunostimulation of the mesotelial macrophages, together with a careful policy in terms of glucose concentration in the dialysate and dwell times may contribute not only to treat different forms of ultrafiltration loss but also to prevent their incidence.

Published
1990

24. Focus vesiculosus: a nephrotoxic alga?

Author

P A Conz, P A Bevilacqua, G. La Greca, P Benedetti, and L Cima

Subjects
Transplantation, Algae, biology, Nephrology, business.industry, Botany, Medicine, Fucus vesiculosus, Medicinal poisoning, business, biology.organism_classification
Published
1998

25. Campylobacter pylori in Uremic Dialyzed Patients

Author

P A Conz, G. La Greca, Stefano Chiaramonte, Mariano Feriani, and C. Ronco

Subjects
business.industry, Campylobacter, medicine, medicine.disease_cause, business, Microbiology
Published
1989

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