1. Deep phenotyping meets big data
- Author
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Lakerveld, J., Wagtendonk, A., Vaartjes, I., Karssenberg, D., Penninx, B., Beulens, J., Timmermans, E., Huisman, M., Kramer, S., van Wier, M., Boomsma, D., Willemsen, G., Schuengel, C., Oosterman, M., Stronks, K., Vermeulen, R., Koster, A., Stehouwer, C., van den Hurk, K., Koomen, E., de Mutsert, R., Have, M., Verschuren, M., Picavet, S., Beenackers, M., van Lenthe, F., Ikram, A., Jaddoe, V., Oldehinkel, T., de Jong, T., Mulder, S., Dotinga, A., Landdegradatie en aardobservatie, Landscape functioning, Geocomputation and Hydrology, Organizational Culture and Change, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Afd Pharmacology, Urban Accessibility and Social Inclusion, Geography and Education, Leerstoel Aken, UU LEG Research USG Public Matters, Spatial Economics, Sociology, The Social Context of Aging (SoCA), Biological Psychology, APH - Mental Health, APH - Methodology, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Health Behaviors & Chronic Diseases, Clinical Child and Family Studies, LEARN! - Child rearing, APH - Aging & Later Life, RS: CAPHRI - R4 - Health Inequities and Societal Participation, Sociale Geneeskunde, MUMC+: Centrum voor Chronische Zieken (3), MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, MUMC+: MA Reumatologie (9), MUMC+: MA Nefrologie (9), MUMC+: MA Medische Oncologie (9), MUMC+: MA Hematologie (9), MUMC+: MA Maag Darm Lever (9), MUMC+: MA Endocrinologie (9), MUMC+: HVC Pieken Maastricht Studie (9), Interne Geneeskunde, MUMC+: MA Interne Geneeskunde (3), Public Health, Epidemiology, Erasmus MC other, Pediatrics, Epidemiology and Data Science, Psychiatry, Amsterdam Neuroscience - Complex Trait Genetics, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, APH - Societal Participation & Health, Otolaryngology / Head & Neck Surgery, APH - Quality of Care, APH - Digital Health, and Public and occupational health
- Subjects
Earth science ,Big data ,010501 environmental sciences ,01 natural sciences ,Health informatics ,DISEASE ,Environmental data ,Data science ,Cohort Studies ,0302 clinical medicine ,030212 general & internal medicine ,Netherlands ,ASSOCIATIONS ,Non-communicabledisease ,Environmental exposure ,Non-communicable disease ,SDG 11 - Sustainable Cities and Communities ,Exposome ,Geography ,Cohort ,lcsh:R858-859.7 ,BURDEN ,medicine.medical_specialty ,General Computer Science ,Health geography ,GREEN ,Environment ,lcsh:Computer applications to medicine. Medical informatics ,Exposure ,03 medical and health sciences ,REGRESSION ,medicine ,Humans ,0105 earth and related environmental sciences ,business.industry ,Research ,Public health ,Prevention ,Public Health, Environmental and Occupational Health ,Environmental Exposure ,AIR-POLLUTION ,General Business, Management and Accounting ,Earth Sciences ,Upstream determinants ,business ,Cohorts ,ENVIRONMENTS - Abstract
Environmental exposures are increasingly investigated as possible drivers of health behaviours and disease outcomes. So-called exposome studies that aim to identify and better understand the effects of exposures on behaviours and disease risk across the life course require high-quality environmental exposure data. The Netherlands has a great variety of environmental data available, including high spatial and often temporal resolution information on urban infrastructure, physico-chemical exposures, presence and availability of community services, and others. Until recently, these environmental data were scattered and measured at varying spatial scales, impeding linkage to individual-level (cohort) data as they were not operationalised as personal exposures, that is, the exposure to a certain environmental characteristic specific for a person. Within the Geoscience and hEalth Cohort COnsortium (GECCO) and with support of the Global Geo Health Data Center (GGHDC), a platform has been set up in The Netherlands where environmental variables are centralised, operationalised as personal exposures, and used to enrich 23 cohort studies and provided to researchers upon request. We here present and detail a series of personal exposure data sets that are available within GECCO to date, covering personal exposures of all residents of The Netherlands (currently about 17 M) over the full land surface of the country, and discuss challenges and opportunities for its use now and in the near future.
- Published
- 2020
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