21 results on '"A. Starflinger"'
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2. Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry
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Proietti, M., Vitolo, M., Harrison, S. L., Lane, D. A., Fauchier, L., Marin, F., Nabauer, M., Potpara, T. S., Dan, G. -A., Boriani, G., Lip, G. Y. H., Boriani (Chair), G., Tavazzi, L., Maggioni, A. P., Potpara, T., Kalarus, Z., Ferrari, R., Shantsila, A., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., Garcia Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E. N., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K., Erglis, A., Poposka, L., Burg, M. R., Crijns, H., Erkuner, O., Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zera, E., Ekmekciu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., Van Genechten, G., Heidbuchel, H., Boussy, T., De Coninck, M., Van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., Van Hauwaert, B., Kuppens, C., Faes, D., Van Lier, D., Van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubickova, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Veno, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castano, S., Cheggour, S., Poulard, J., Mouquet, V., Leparree, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassaliere, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois-Jacquey, C., Kassim, H., Marijon, E., Le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden-Lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefevre, M., Mingam, R., Haissaguerre, M., Le Bidan, M., Pavin, D., Le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer-Bouchard, C., Da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Gloggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Koster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Fortsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Landle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hotz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schon, B., Schon, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler-Schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., Di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V. L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum-Bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Burg, M., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., De Groot, J., Neefs, J., van den Berg, N., Piersma, F., Wilde, A., Hagens, V., Van Es, J., Van Opstal, J., Van Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., van Doorn, W., Szili-Torok, T., Bhagwandien, R., Janse, P., Muskens, A., van Eck, M., Gevers, R., van der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch-Fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik-Sztylc, A., Czapla, W., Mroz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska-Filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor-Broda, M., Biedron, M., Gasior, Z., Kolodziej, M., Janion, M., Gorczyca-Michta, I., Wozakowska-Kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc-Dyl, E., Miarka, J., Pasieka, M., Zieminska-Luc, M., Bujak, W., Sliwinski, A., Grech, A., Morka, J., Petrykowska, K., Prasal, M., Hordynski, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Wozniak, P., Chlebus, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kazmierczak, J., Przybylska, A., Skorek, E., Blaszczyk, H., Stepien, M., Szabowski, S., Krysiak, W., Szymanska, M., Karasinski, J., Blicharz, J., Skura, M., Halas, K., Michalczyk, L., Orski, Z., Krzyzanowski, K., Skrobowski, A., Zielinski, L., Tomaszewska-Kiecana, M., Dluzniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tyminska, A., Ozieranski, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik-Lydka, A., Leopold-Jadczyk, A., Jedrzejczyk-Patej, E., Koziel, M., Mazurek, M., Krzemien-Wolska, K., Starosta, P., Nowalany-Kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandao Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragao, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhaes, P., Fontes, P., Leao, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Loachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Polovina, M., Vujisic-Tesic, B., Nedeljkovic, M., Zlatar, M., Asanin, M., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Kovacevic, S., Garcia Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldan Rabadan, I., Gil Ortega, M., Tello Montoliu, A., Orenes Pinero, E., Manzano Fernandez, S., Romero Aniorte, A., Veliz Martinez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., Garcia-Bolao, I., Bertomeu Gonzalez, V., Otero-Ravina, F., Garcia Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil-Baron, P., Koc, M., Onrat, E., Dural, I. E., Yilmaz, K., Ozin, B., Tan Kurklu, S., Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A. K., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U. O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M. B., Kutlu, M., Demir, M., Gibbs, C., Kaminskiene, S., Bryce, M., Skinner, A., Belcher, G., Hunt, J., Stancombe, L., Holbrook, B., Peters, C., Tettersell, S., Senoo, K., Russell, K., Domingos, P., Hussain, S., Partridge, J., Haynes, R., Bahadur, S., Brown, R., Mcmahon, S., Lip, G., Mcdonald, J., Balachandran, K., Singh, R., Garg, S., Desai, H., Davies, K., Goddard, W., Galasko, G., Rahman, I., Chua, Y., Payne, O., Preston, S., Brennan, O., Pedley, L., Whiteside, C., Dickinson, C., Brown, J., Jones, K., Benham, L., Brady, R., Buchanan, L., Ashton, A., Crowther, H., Fairlamb, H., Thornthwaite, S., Relph, C., Mcskeane, A., Poultney, U., Kelsall, N., Rice, P., Wilson, T., Wrigley, M., Kaba, R., Patel, T., Young, E., Law, J., Runnett, C., Thomas, H., Mckie, H., Fuller, J., Pick, S., Sharp, A., Hunt, A., Thorpe, K., Hardman, C., Cusack, E., Adams, L., Hough, M., Keenan, S., Bowring, A., Watts, J., Zaman, J., Goffin, K., Nutt, H., Beerachee, Y., Featherstone, J., Mills, C., Pearson, J., Stephenson, L., Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., Mckinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., Mckenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O'Donohoe, L., Mozid, A., Dymond, H., Lloyd-Jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt-Kerby, T., Proietti M, Vitolo M, Harrison SL, Lane DA, Fauchier L, Marin F, Nabauer M, Potpara TS, Dan GA, Boriani G, Lip GYH, ESC-EHRA EORP-AF Long-Term General Registry Investigators, Diemberger I, Ziacchi M, Frisoni J, Cardiology, ACS - Heart failure & arrhythmias, Graduate School, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de cardiologie
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Registrie ,Research Report ,medicine.medical_specialty ,Major adverse outcome ,Cardiovascular risk factors ,Cluster analysis ,Risk Factors ,Internal medicine ,Clinical phenotype ,Atrial Fibrillation ,Epidemiology ,Humans ,Medicine ,Registries ,Cluster analysi ,Atrial fibrillation ,Clinical management ,Clinical phenotypes ,Major adverse outcomes ,Phenotype ,business.industry ,Proportional hazards model ,Risk Factor ,Hazard ratio ,General Medicine ,medicine.disease ,Confidence interval ,Cohort ,Observational study ,business ,Research Article ,Human - Abstract
Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results A total of 9363 were available for this analysis. We identified three clusters: Cluster 1 (n = 3634; 38.8%) characterized by older patients and prevalent non-cardiac comorbidities; Cluster 2 (n = 2774; 29.6%) characterized by younger patients with low prevalence of comorbidities; Cluster 3 (n = 2955;31.6%) characterized by patients’ prevalent cardiovascular risk factors/comorbidities. Over a mean follow-up of 22.5 months, Cluster 3 had the highest rate of cardiovascular events, all-cause death, and the composite outcome (combining the previous two) compared to Cluster 1 and Cluster 2 (all P < .001). An adjusted Cox regression showed that compared to Cluster 2, Cluster 3 (hazard ratio (HR) 2.87, 95% confidence interval (CI) 2.27–3.62; HR 3.42, 95%CI 2.72–4.31; HR 2.79, 95%CI 2.32–3.35), and Cluster 1 (HR 1.88, 95%CI 1.48–2.38; HR 2.50, 95%CI 1.98–3.15; HR 2.09, 95%CI 1.74–2.51) reported a higher risk for the three outcomes respectively. Conclusions In European AF patients, three main clusters were identified, differentiated by differential presence of comorbidities. Both non-cardiac and cardiac comorbidities clusters were found to be associated with an increased risk of major adverse outcomes.
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- 2021
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3. ATHLET extensions for the simulation of supercritical carbon dioxide driven power cycles
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Jörg Starflinger, Michael Buck, and Markus Hofer
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Nuclear and High Energy Physics ,Radiation ,Supercritical carbon dioxide ,business.industry ,020209 energy ,Nuclear engineering ,System safety ,02 engineering and technology ,Nuclear power ,01 natural sciences ,Supercritical fluid ,010305 fluids & plasmas ,Power (physics) ,Nuclear Energy and Engineering ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,Environmental science ,General Materials Science ,Safety, Risk, Reliability and Quality ,business - Abstract
The Fukushima accident reveals the need for additional safety systems for nuclear power plants. One promising option is the supercritical carbon-dioxide (sCO2) heat removal system, which consists of a simple Brayton cycle. This study provides an overview of the extensions and validation of the thermal-hydraulic system code ATHLET for the simulation of sCO2 power cycles, especially with regard to the sCO2 heat removal system. The properties of CO2, heat transfer and pressure drop correlations, as well as compact heat exchanger and turbomachinery modelling are considered.
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- 2019
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4. Bazaar-Contract: A Smart Contract for Binding Multi-Round Bilateral Negotiations on Cloud Markets
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Benedikt Pittl, Stefan Starflinger, Werner Mach, and Erich Schikuta
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File system ,Service quality ,Smart contract ,Computer science ,Transparency (market) ,business.industry ,media_common.quotation_subject ,Cloud computing ,02 engineering and technology ,Computer security ,computer.software_genre ,Technical feasibility ,Negotiation ,Virtual machine ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,business ,computer ,media_common - Abstract
Amazon's EC2 On-Demand marketspace is the dominant platform for trading Cloud services such as virtual machines. On such platforms consumers and providers do not negotiate with each other. Instead, consumers purchase predefined virtual machines at fixed-prices and so this approach is also termed take-it-or-leave-it approach. In the last years more dynamic platforms emerged such as Amazon's spot marketspace which was relaunched at the end of 2017 - here consumers can bid for virtual machines. The recent efforts of Amazon and other Cloud providers such as VirtuStream show that dynamic trading mechanisms are a promising approach for realizing future Cloud markets. Hence, multi-round bilateral negotiations which are executed autonomously have gained popularity in the scientific community. A key challenge towards the adoption of autonomous multi-round bilateral negotiations is to ensure the integrity and transparency so that the generated agreements are legally biding. In the paper at hand we present an approach which uses a smart contract - called Bazaar-Contract - to ensure integrity and transparency during multi-round bilateral negotiations. Thereby, consumers and providers exchange offers by calling methods of the Bazaar-Contract. Moreover, Cloud referees can use these Bazaar-Contracts in order to manage penalties resulting from poor service quality. In order to prove the technical feasibility of our approach we implemented the Bazaar-Contract using Ethereum and the Inter-Planetary File System. We evaluate the economical feasibility of our approach by considering the gas costs.
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- 2019
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5. Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Registry
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Zakine, Cyril, Garcia, Rodrigue, Narayanan, Kumar, Gandjbakhch, Estelle, Algalarrondo, Vincent, Lellouche, Nicolas, Perier, Marie-Cécile, Fauchier, Laurent, Gras, Daniel, Bordachar, Pierre, Piot, Olivier, Babuty, Dominique, Sadoul, Nicolas, Defaye, Pascal, Deharo, Jean-Claude, Klug, Didier, Leclercq, Christophe, Extramiana, Fabrice, Boveda, Serge, Marijon, Eloi, Maury, Philippe, Alonso, Christine, Anselme, Frederic, Hermida, Jean-Sylvain, Laurent, Gabriel, Mansourati, Jacques, Sacher, Frederic, Taieb, Jérôme, Boriani, Giuseppe, Proietti, Marco, Laroche, Cécile, Marin, Francisco, Nabauer, Michael, Potpara, Tatjana, Dan, Gheorghe-Andrei, Kalarus, Zbigniew, Tavazzi, Luigi, Maggioni, Aldo, Lip, Gregory, Dan, G-A, Goda, A, Mairesse, G, Shalganov, T, Antoniades, L, Taborsky, M, Riahi, S, Muda, P, García Bolao, I, Etsadashvili, K, Simantirakis, E, Haim, M, Azhari, A, Najafian, J, Santini, M, Mirrakhimov, E, a Kulzida, K, Erglis, A, Poposka, L, Burg, M, Crijns, H, Erküner, Ö, Atar, D, Lenarczyk, R, Martins Oliveira, M, Shah, D, Serdechnaya, E, Diker, E, Lane, D, Zëra, E, Ekmekçiu, U, Paparisto, V, Tase, M, Gjergo, H, Dragoti, J, Ciutea, M, Ahadi, N, El Husseini, Z, Raepers, M, Leroy, J, Haushan, P, Jourdan, A, Lepiece, C, Desteghe, L, Vijgen, J, Koopman, P, van Genechten, G, Heidbuchel, H, Boussy, T, de Coninck, M, van Eeckhoutte, H, Bouckaert, N, Friart, A, Boreux, J, Arend, C, Evrard, P, Stefan, L, Hoffer, E, Herzet, J, Massoz, M, Celentano, C, Sprynger, M, Pierard, L, Melon, P, van Hauwaert, B, Kuppens, C, Faes, D, van Lier, D, van Dorpe, A, Gerardy, A, Deceuninck, O, Xhaet, O, Dormal, F, Ballant, E, Blommaert, D, Yakova, D, Hristov, M, Yncheva, T, Stancheva, N, Tisheva, S, Tokmakova, M, Nikolov, F, Gencheva, D, Kunev, B, Stoyanov, M, Marchov, D, Gelev, V, Traykov, V, Kisheva, A, Tsvyatkov, H, Shtereva, R, Bakalska-Georgieva, S, Slavcheva, S, Yotov, Y, Kubíčková, M, Marni Joensen, A, Gammelmark, A, Hvilsted Rasmussen, L, Dinesen, P, Krogh Venø, S, Sorensen, B, Korsgaard, A, Andersen, K, Fragtrup Hellum, C, Svenningsen, A, Nyvad, O, Wiggers, P, May, O, Aarup, A, Graversen, B, Jensen, L, Andersen, M, Svejgaard, M, Vester, S, Hansen, S, Lynggaard, V, Ciudad, M, Vettus, R, Maestre, A, Castaño, S, Cheggour, S, Poulard, J, Mouquet, V, Leparrée, S, Bouet, J, Doucy, A, Duquenne, H, Furber, A, Dupuis, J, Rautureau, J, Font, M, Damiano, P, Lacrimini, M, Abalea, J, Boismal, S, Menez, T, Range, G, Gorka, H, Laure, C, Vassalière, C, Elbaz, N, Djouadi, K, Roubille, F, Dietz, D, Davy, J, Granier, M, Winum, P, Leperchois-Jacquey, C, Kassim, H, Le Heuzey, J, Fedida, J, Maupain, C, Himbert, C, Hidden-Lucet, F, Duthoit, G, Badenco, N, Chastre, T, Waintraub, X, Oudihat, M, Lacoste, J, Stephan, C, Bader, H, Delarche, N, Giry, L, Arnaud, D, Lopez, C, Boury, F, Brunello, I, Lefèvre, M, Mingam, R, Haissaguerre, M, Le Bidan, M, Pavin, D, Le Moal, V, Beitar, T, Martel, I, Schmid, A, Sadki, N, Romeyer-Bouchard, C, da Costa, A, Arnault, I, Boyer, M, Piat, C, Lozance, N, Nastevska, S, Doneva, A, Fortomaroska Milevska, B, Sheshoski, B, Petroska, K, Taneska, N, Bakrecheski, N, Lazarovska, K, Jovevska, S, Ristovski, V, Antovski, A, Lazarova, E, Kotlar, I, Taleski, J, Kedev, S, Zlatanovik, N, Jordanova, S, Bajraktarova Proseva, T, Doncovska, S, Maisuradze, D, Esakia, A, Sagirashvili, E, Lartsuliani, K, Natelashvili, N, Gumberidze, N, Gvenetadze, R, Gotonelia, N, Kuridze, N, Papiashvili, G, Menabde, I, Glöggler, S, Napp, A, Lebherz, C, Romero, H, Schmitz, K, Berger, M, Zink, M, Köster, S, Sachse, J, Vonderhagen, E, Soiron, G, Mischke, K, Reith, R, Schneider, M, Rieker, W, Boscher, D, Taschareck, A, Beer, A, Oster, D, Ritter, O, Adamczewski, J, Walter, S, Frommhold, A, Luckner, E, Richter, J, Schellner, M, Landgraf, S, Bartholome, S, Naumann, R, Schoeler, J, Westermeier, D, William, F, Wilhelm, K, Maerkl, M, Oekinghaus, R, Denart, M, Kriete, M, Tebbe, U, Scheibner, T, Gruber, M, Gerlach, A, Beckendorf, C, Anneken, L, Arnold, M, Lengerer, S, Bal, Z, Uecker, C, Förtsch, H, Fechner, S, Mages, V, Martens, E, Methe, H, Schmidt, T, Schaeffer, B, Hoffmann, B, Moser, J, Heitmann, K, Willems, S, Klaus, C, Lange, I, Durak, M, Esen, E, Mibach, F, Mibach, H, Utech, A, Gabelmann, M, Stumm, R, Ländle, V, Gartner, C, Goerg, C, Kaul, N, Messer, S, Burkhardt, D, Sander, C, Orthen, R, Kaes, S, Baumer, A, Dodos, F, Barth, A, Schaeffer, G, Gaertner, J, Winkler, J, Fahrig, A, Aring, J, Wenzel, I, Steiner, S, Kliesch, A, Kratz, E, Winter, K, Schneider, P, Haag, A, Mutscher, I, Bosch, R, Taggeselle, J, Meixner, S, Schnabel, A, Shamalla, A, Hötz, H, Korinth, A, Rheinert, C, Mehltretter, G, Schön, B, Schön, N, Starflinger, A, Englmann, E, Baytok, G, Laschinger, T, Ritscher, G, Gerth, A, Dechering, D, Eckardt, L, Kuhlmann, M, Proskynitopoulos, N, Brunn, J, Foth, K, Axthelm, C, Hohensee, H, Eberhard, K, Turbanisch, S, Hassler, N, Koestler, A, Stenzel, G, Kschiwan, D, Schwefer, M, Neiner, S, Hettwer, S, Haeussler-Schuchardt, M, Degenhardt, R, Sennhenn, S, Brendel, M, Stoehr, A, Widjaja, W, Loehndorf, S, Logemann, A, Hoskamp, J, Grundt, J, Block, M, Ulrych, R, Reithmeier, A, Panagopoulos, V, Martignani, C, Bernucci, D, Fantecchi, E, Diemberger, I, Ziacchi, M, Biffi, M, Cimaglia, P, Frisoni, J, Giannini, I, Boni, S, Fumagalli, S, Pupo, S, Di Chiara, A, Mirone, P, Pesce, F, Zoccali, C, Malavasi, V, Mussagaliyeva, A, Ahyt, B, Salihova, Z, Koshum-Bayeva, K, Kerimkulova, A, Bairamukova, A, Lurina, B, Zuzans, R, Jegere, S, Mintale, I, Kupics, K, Jubele, K, Kalejs, O, Vanhear, K, Cachia, M, Abela, E, Warwicker, S, Tabone, T, Xuereb, R, Asanovic, D, Drakalovic, D, Vukmirovic, M, Pavlovic, N, Music, L, Bulatovic, N, Boskovic, A, Uiterwaal, H, Bijsterveld, N, de Groot, J, Neefs, J, van den Berg, N, Piersma, F, Wilde, A, Hagens, V, van Es, J, van Opstal, J, van Rennes, B, Verheij, H, Breukers, W, Tjeerdsma, G, Nijmeijer, R, Wegink, D, Binnema, R, Said, S, Philippens, S, van Doorn, W, Szili-Torok, T, Bhagwandien, R, Janse, P, Muskens, A, van Eck, M, Gevers, R, van Der Ven, N, Duygun, A, Rahel, B, Meeder, J, Vold, A, Holst Hansen, C, Engset, I, Dyduch-Fejklowicz, B, Koba, E, Cichocka, M, Sokal, A, Kubicius, A, Pruchniewicz, E, Kowalik-Sztylc, A, Czapla, W, Mróz, I, Kozlowski, M, Pawlowski, T, Tendera, M, Winiarska-Filipek, A, Fidyk, A, Slowikowski, A, Haberka, M, Lachor-Broda, M, Biedron, M, Gasior, Z, Kołodziej, M, Janion, M, Gorczyca-Michta, I, Wozakowska-Kaplon, B, Stasiak, M, Jakubowski, P, Ciurus, T, Drozdz, J, Simiera, M, Zajac, P, Wcislo, T, Zycinski, P, Kasprzak, J, Olejnik, A, Harc-Dyl, E, Miarka, J, Pasieka, M, Ziemińska-Łuć, M, Bujak, W, Śliwiński, A, Grech, A, Morka, J, Petrykowska, K, Prasał, M, Hordyński, G, Feusette, P, Lipski, P, Wester, A, Streb, W, Romanek, J, Woźniak, P, Chlebuś, M, Szafarz, P, Stanik, W, Zakrzewski, M, Kaźmierczak, J, Przybylska, A, Skorek, E, Błaszczyk, H, Stępień, M, Szabowski, S, Krysiak, W, Szymańska, M, Karasiński, J, Blicharz, J, Skura, M, Hałas, K, Michalczyk, L, Orski, Z, Krzyżanowski, K, Skrobowski, A, Zieliński, L, Tomaszewska-Kiecana, M, Dłużniewski, M, Kiliszek, M, Peller, M, Budnik, M, Balsam, P, Opolski, G, Tymińska, A, Ozierański, K, Wancerz, A, Borowiec, A, Majos, E, Dabrowski, R, Szwed, H, Musialik-Lydka, A, Leopold-Jadczyk, A, Jedrzejczyk-Patej, E, Koziel, M, Mazurek, M, Krzemien-Wolska, K, Starosta, P, Nowalany-Kozielska, E, Orzechowska, A, Szpot, M, Staszel, M, Almeida, S, Pereira, H, Brandão Alves, L, Miranda, R, Ribeiro, L, Costa, F, Morgado, F, Carmo, P, Galvao Santos, P, Bernardo, R, Adragão, P, Ferreira da Silva, G, Peres, M, Alves, M, Leal, M, Cordeiro, A, Magalhães, P, Fontes, P, Leão, S, Delgado, A, Costa, A, Marmelo, B, Rodrigues, B, Moreira, D, Santos, J, Santos, L, Terchet, A, Darabantiu, D, Mercea, S, Turcin Halka, V, Pop Moldovan, A, Gabor, A, Doka, B, Catanescu, G, Rus, H, Oboroceanu, L, Bobescu, E, Popescu, R, Dan, A, Buzea, A, Daha, I, Neuhoff, I, Baluta, M, Ploesteanu, R, Dumitrache, N, Vintila, M, Daraban, A, Japie, C, Badila, E, Tewelde, H, Hostiuc, M, Frunza, S, Tintea, E, Bartos, D, Ciobanu, A, Popescu, I, Toma, N, Gherghinescu, C, Cretu, D, Patrascu, N, Stoicescu, C, Udroiu, C, Bicescu, G, Vintila, V, Vinereanu, D, Cinteza, M, Rimbas, R, Grecu, M, Cozma, A, Boros, F, Ille, M, Tica, O, Tor, R, Corina, A, Jeewooth, A, Maria, B, Georgiana, C, Natalia, C, Alin, D, Dinu-Andrei, D, Livia, M, Daniela, R, Larisa, R, Umaar, S, Tamara, T, Ioachim Popescu, M, Nistor, D, Sus, I, Coborosanu, O, Alina-Ramona, N, Dan, R, Petrescu, L, Ionescu, G, Vacarescu, C, Goanta, E, Mangea, M, Ionac, A, Mornos, C, Cozma, D, Pescariu, S, Solodovnicova, E, Soldatova, I, Shutova, J, Tjuleneva, L, Zubova, T, Uskov, V, Obukhov, D, Rusanova, G, Isakova, N, Odinsova, S, Arhipova, T, Kazakevich, E, Zavyalova, O, Novikova, T, Riabaia, I, Zhigalov, S, Drozdova, E, Luchkina, I, Monogarova, Y, Hegya, D, Rodionova, L, Nevzorova, V, Lusanova, O, Arandjelovic, A, Toncev, D, Vukmirovic, L, Radisavljevic, M, Milanov, M, Sekularac, N, Zdravkovic, M, Hinic, S, Dimkovic, S, Acimovic, T, Saric, J, Radovanovic, S, Kocijancic, A, Obrenovic-Kircanski, B, Kalimanovska Ostric, D, Simic, D, Jovanovic, I, Petrovic, I, Polovina, M, Vukicevic, M, Tomasevic, M, Mujovic, N, Radivojevic, N, Petrovic, O, Aleksandric, S, Kovacevic, V, Mijatovic, Z, Ivanovic, B, Tesic, M, Ristic, A, Vujisic-Tesic, B, Nedeljkovic, M, Karadzic, A, Uscumlic, A, Prodanovic, M, Zlatar, M, Asanin, M, Bisenic, B, Vasic, V, Popovic, Z, Djikic, D, Sipic, M, Peric, V, Dejanovic, B, Milosevic, N, Backovic, S, Stevanovic, A, Andric, A, Pencic, B, Pavlovic-Kleut, M, Celic, V, Pavlovic, M, Petrovic, M, Vuleta, M, Petrovic, N, Simovic, S, Savovic, Z, Milanov, S, Davidovic, G, Iric-Cupic, V, Djordjevic, D, Damjanovic, M, Zdravkovic, S, Topic, V, Stanojevic, D, Randjelovic, M, Jankovic-Tomasevic, R, Atanaskovic, V, Antic, S, Simonovic, D, Stojanovic, M, Stojanovic, S, Mitic, V, Ilic, V, Petrovic, D, Deljanin Ilic, M, Ilic, S, Stoickov, V, Markovic, S, Mijatovic, A, Tanasic, D, Radakovic, G, Peranovic, J, Panic-Jelic, N, Vujadinovic, O, Pajic, P, Bekic, S, Kovacevic, S, García Fernandez, A, Perez Cabeza, A, Anguita, M, Tercedor Sanchez, L, Mau, E, Loayssa, J, Ayarra, M, Carpintero, M, Roldán Rabadan, I, Gil Ortega, M, Tello Montoliu, A, Orenes Piñero, E, Manzano Fernández, S, Romero Aniorte, A, Veliz Martínez, A, Quintana Giner, M, Ballesteros, G, Palacio, M, Alcalde, O, García-Bolao, I, Bertomeu Gonzalez, V, Otero-Raviña, F, García Seara, J, Gonzalez Juanatey, J, Dayal, N, Maziarski, P, Gentil-Baron, P, Koç, M, Onrat, E, Dural, I, Yilmaz, K, Özin, B, Tan Kurklu, S, Atmaca, Y, Canpolat, U, Tokgozoglu, L, Dolu, A, Demirtas, B, Sahin, D, Ozcan Celebi, O, Gagirci, G, Turk, U, Ari, H, Polat, N, Toprak, N, Sucu, M, Akin Serdar, O, Taha Alper, A, Kepez, A, Yuksel, Y, Uzunselvi, A, Yuksel, S, Sahin, M, Kayapinar, O, Ozcan, T, Kaya, H, Yilmaz, M, Kutlu, M, Demir, M, Gibbs, C, Kaminskiene, S, Bryce, M, Skinner, A, Belcher, G, Hunt, J, Stancombe, L, Holbrook, B, Peters, C, Tettersell, S, Shantsila, A, Senoo, K, Russell, K, Domingos, P, Hussain, S, Partridge, J, Haynes, R, Bahadur, S, Brown, R, Mcmahon, S, Mcdonald, J, Balachandran, K, Singh, R, Garg, S, Desai, H, Davies, K, Goddard, W, Galasko, G, Rahman, I, Chua, Y, Payne, O, Preston, S, Brennan, O, Pedley, L, Whiteside, C, Dickinson, C, Brown, J, Jones, K, Benham, L, Brady, R, Buchanan, L, Ashton, A, Crowther, H, Fairlamb, H, Thornthwaite, S, Relph, C, Mcskeane, A, Poultney, U, Kelsall, N, Rice, P, Wilson, T, Wrigley, M, Kaba, R, Patel, T, Young, E, Law, J, Runnett, C, Thomas, H, Mckie, H, Fuller, J, Pick, S, Sharp, A, Hunt, A, Thorpe, K, Hardman, C, Cusack, E, Adams, L, Hough, M, Keenan, S, Bowring, A, Watts, J, Zaman, J, Goffin, K, Nutt, H, Beerachee, Y, Featherstone, J, Mills, C, Pearson, J, Stephenson, L, Grant, S, Wilson, A, Hawksworth, C, Alam, I, Robinson, M, Ryan, S, Egdell, R, Gibson, E, Holland, M, Leonard, D, Mishra, B, Ahmad, S, Randall, H, Hill, J, Reid, L, George, M, Mckinley, S, Brockway, L, Milligan, W, Sobolewska, J, Muir, J, Tuckis, L, Winstanley, L, Jacob, P, Kaye, S, Morby, L, Jan, A, Sewell, T, Boos, C, Wadams, B, Cope, C, Jefferey, P, Andrews, N, Getty, A, Suttling, A, Turner, C, Hudson, K, Austin, R, Howe, S, Iqbal, R, Gandhi, N, Brophy, K, Mirza, P, Willard, E, Collins, S, Ndlovu, N, Subkovas, E, Karthikeyan, V, Waggett, L, Wood, A, Bolger, A, Stockport, J, Evans, L, Harman, E, Starling, J, Williams, L, Saul, V, Sinha, M, Bell, L, Tudgay, S, Kemp, S, Frost, L, Ingram, T, Loughlin, A, Adams, C, Adams, M, Hurford, F, Owen, C, Miller, C, Donaldson, D, Tivenan, H, Button, H, Nasser, A, Jhagra, O, Stidolph, B, Brown, C, Livingstone, C, Duffy, M, Madgwick, P, Roberts, P, Greenwood, E, Fletcher, L, Beveridge, M, Earles, S, Mckenzie, D, Beacock, D, Dayer, M, Seddon, M, Greenwell, D, Luxton, F, Venn, F, Mills, H, Rewbury, J, James, K, Roberts, K, Tonks, L, Felmeden, D, Taggu, W, Summerhayes, A, Hughes, D, Sutton, J, Felmeden, L, Khan, M, Walker, E, Norris, L, O'Donohoe, L, Mozid, A, Dymond, H, Lloyd-Jones, H, Saunders, G, Simmons, D, Coles, D, Cotterill, D, Beech, S, Kidd, S, Wrigley, B, Petkar, S, Smallwood, A, Jones, R, Radford, E, Milgate, S, Metherell, S, Cottam, V, Buckley, C, Broadley, A, Wood, D, Allison, J, Rennie, K, Balian, L, Howard, L, Pippard, L, Board, S, Pitt-Kerby, T, Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre hospitalier universitaire de Poitiers (CHU Poitiers), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Université de Montréal (UdeM), Service de cardiologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service de cardiologie [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), Cardiopathies et mort subite [ERL 3147], Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] (CRCTB), Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), Biospectroscopie Translationnelle - EA 7506 (BIOSPECT), Université de Reims Champagne-Ardenne (URCA), Service de Cardiologie B, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Cardiac Stimulation and Rhythmology, CHU Grenoble, Department of Cardiology and Cardiovascular Surgery, CHU Michallon, Grenoble, France, CHU Marseille, CHU Lille, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Clinique Pasteur, Clinique Pasteur [Toulouse], Service de cardiologie [CHU HEGP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Hôpital Ambroise Paré [AP-HP], Service de cardiologie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), CHU Dijon, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Hôpital de la Cavale Blanche - CHRU Brest (CHU - BREST ), Centre Hospitalier du Pays d'Aix, Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), Università degli Studi di Milano = University of Milan (UNIMI), Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, University of Liverpool, Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Necker - Enfants Malades [AP-HP], Universidad de Murcia, University of Belgrade [Belgrade], Colentina University Hospital, University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), Silesian Medical University, Katowice, Poland, Maria Cecilia Hospital [Cotignola], Research Center [Associazione Nazionale Medici Cardiologi Ospedalieri] (ANMCO Research Center), Associazione Nazionale Medici Cardiologi Ospedalieri [Firenze] (ANMCO), Aalborg University [Denmark] (AAU), Abbott Vascular Int., Amgen Cardiovascular, Novartis Pharma AG, Sanofi, SERVIER, Atrial Fibrillation NETwork, AFNET, AstraZeneca, Bayer AG, Boehringer Ingelheim, Boston Scientific, The Bristol Myers Squibb and Pfizer Alliance, Alliance Daiichi Sankyo Europe GmbH and Eli Lilly and Company, Gedeon Richter Plc., Menarini Int. Op., UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Service de Pharmacologie médicale [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de Cardiologie [CHU Pitié-Salpêtrière], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-CHU Trousseau [APHP], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), and CHU Toulouse [Toulouse]
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Adult ,Male ,Acute coronary syndrome ,medicine.medical_specialty ,medicine.drug_class ,Hemorrhage ,Outcomes ,030204 cardiovascular system & hematology ,Lower risk ,Risk Assessment ,[SHS]Humanities and Social Sciences ,03 medical and health sciences ,0302 clinical medicine ,Fibrinolytic Agents ,Risk Factors ,Physiology (medical) ,Internal medicine ,Cause of Death ,Antithrombotic ,Medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,Registries ,Practice Patterns, Physicians' ,Stroke ,Aged ,EORP-AF registry ,Aged, 80 and over ,Antithrombotic therapy ,business.industry ,Proportional hazards model ,Atrial fibrillation ,Vitamin K antagonist ,Middle Aged ,medicine.disease ,Observational registries ,Europe ,Female ,Cardiology and Cardiovascular Medicine ,business ,Fibrinolytic agent ,Follow-Up Studies - Abstract
Aims In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed. Methods and results We report 1-year follow-up data from the EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry. Outcomes were assessed according to antithrombotic therapy. At 1-year follow-up, 9663 (88.0%) patients had available data for analysis: 586 (6.1%) were not treated with any antithrombotic; 681 (7.0%) with antiplatelets only; 4066 (42.1%) with vitamin K antagonist (VKA) only; 3167 (32.8%) with NOACs only; and 1163 (12.0%) with antiplatelet and oral anticoagulant. At 1-year follow-up, there was a low rate of stroke (0.7%) and any thromboembolic event (TE) (1.2%), while haemorrhagic events occurred in 222 patients (2.3%). Cardiovascular (CV) death and all-cause death occurred in 3.9% and 5.2% of patients, respectively. Cumulative survival for all the three main outcomes considered was highest amongst patients treated only with NOACs (P Conclusion The 1-year follow-up of EORP-AF General Long-Term Registry reported a low occurrence of thromboembolic and haemorrhagic events, although mortality was high. Both VKA and NOACs were associated with a lower risk of all main adverse outcomes. All treatments were associated with a lower risk for CV death and all-cause death.
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- 2019
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6. Recent numerical simulations and experiments on coolability of debris beds during severe accidents of light water reactors
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Jörg Starflinger, Rudi Kulenovic, Michael Buck, M. Rashid, S. Rahman, A. Hartmann, and S. Leininger
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Nuclear and High Energy Physics ,Engineering ,business.industry ,Mechanical Engineering ,Nuclear engineering ,Debris ,Debris bed ,Nuclear Energy and Engineering ,Heat flux ,General Materials Science ,Geotechnical engineering ,Safety, Risk, Reliability and Quality ,business ,Waste Management and Disposal ,Reactor pressure vessel - Abstract
In the course of a severe accident in light water reactors with core degradation, so-called debris beds can be formed inside the reactor pressure vessel or in the reactor cavity. The strategy to analyse the coolability of such debris beds with both experiments and numerical simulations is discussed. The numerical simulations are carried out with MEWA (MElt WAter) code, being developed at the institute for the prediction of the thermal-hydraulic conditions inside a debris bed, including the prediction of dryout heat flux. The simulations show good agreement with experimental data of the DEBRIS experiments.
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- 2015
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7. Setup of the Supercritical CO2 Test-Facility 'Scarlett' for Basic Experimental Investigations of a Compact Heat Exchanger for an Innovative Decay Heat Removal System
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Joerg Starflinger, Wolfgang Flaig, and Rainer Mertz
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Materials science ,business.industry ,Storage tank ,Heat exchanger ,Heat transfer ,Mechanical engineering ,Heat transfer coefficient ,Decay heat ,business ,Supercritical fluid ,Thermal energy ,Coolant - Abstract
Supercritical fluids show great potential as future coolants for nuclear reactors, thermal power and solar power plants. Compared to the subcritical condition, supercritical fluids show advantages in heat transfer due to thermodynamic properties near the critical point. This can lead to the development of more compact and more efficient components, e.g. heat exchanger and compressors. A specific field of interest is a new decay heat removal system for nuclear power plants which is based on a turbine-compressor-system with supercritical CO2 as the working fluid. In case of a station blackout this system converts the decay heat into excess electricity and low-temperature waste heat, which can be emitted to the ambient air. This scenario has already been investigated by means of the thermo-hydraulic code ATHLET, numerically demonstrating the operation of this system for more than 72 h. The practical demonstration is carried out within the Project “sCO2-HeRo”, funded by the European Commission, in which a small scale demonstration unit of the turbo compressor shall be installed at the PWR glass model at GfS, Essen, Germany. To guarantee the retrofitting of this decay heat removal system into existing nuclear power plants, the heat exchanger needs to be as compact and efficient as possible. Therefore, a diffusion welded plate heat exchanger (DWHE) was developed and manufactured at IKE. It has been designed with rectangular mini-channels (0.5–3 mm hydraulic diameter) to ensure high compactness and high heat transfer coefficients. Due to uncertainties the DWHE has to be tested in regard to the actual possible transferrable heat power and to the pressure loss. According to this demand a multipurpose facility has been built at IKE for various experimental investigations on supercritical CO2, which is in operation now. It consists of a closed loop where the CO2 is compressed to supercritical state and delivered to the test section. The test section itself can be exchanged by other ones for various investigations. After the test section, the CO2 pressure is reduced and the liquid is stored in storage tanks, from where it is evaporated and compressed again. The test facility is designed to carry out experimental investigations with CO2 mass flows up to 0.111 kg/s, pressures up to 12 MPa and temperatures up to 150 °C. The first subject of interest will be the study of the thermal behavior of a DWHE using supercritical CO2 as a working fluid close to its critical point. Experiments concerning pressure loss and heat transfer will be carried out as a start for fundamental investigation of heat transfer in mini-channels. This paper contains a detailed description of the test facility, of the first test section and first results regarding heat transfer power and pressure loss.
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- 2017
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8. Safety assessments and severe accidents, impact of external events on nuclear power plants and on mitigation strategies
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Gisela Niedermayer, A. Miassoedov, Holger Nowack, Ahmed Bentaib, Florian Fichot, Jean-Pierre Van Dorsselaere, Joerg Starflinger, and T. Albiol
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European level ,business.industry ,020209 energy ,02 engineering and technology ,Nuclear power ,lcsh:TK9001-9401 ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,Work (electrical) ,Risk analysis (engineering) ,Accident management ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,lcsh:Nuclear engineering. Atomic power ,HERO ,business - Abstract
The Fukushima-Daiichi accidents in 2011 underlined the importance of severe accident management (SAM), including external events, in nuclear power plants (NPP) and the need of implementing efficient mitigation strategies. To this end, the Euratom work programmes for 2012 and 2013 was focused on nuclear safety, in particular on the management of a possible severe accident at the European level. Relying upon the outcomes of the successful Euratom SARNET and SARNET2 projects, new projects were launched addressing the highest priority issues, aimed at reducing the uncertainties still affecting the main phenomena. Among them, PASSAM and IVMR project led by IRSN, ALISA and SAFEST projects led by KIT, CESAM led by GRS and sCO2-HeRO lead by the University of Duisburg-Essen. The aim of the present paper is to give an overview on the main outcomes of these projects.
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- 2020
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9. Development of a coupled neutronic/thermal-hydraulic tool with multi-scale capabilities and applications to HPLWR core analysis
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Lanfranco Monti, Thomas Schulenberg, and Jörg Starflinger
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Nuclear and High Energy Physics ,Engineering ,Neutron transport ,business.industry ,Mechanical Engineering ,Mechanical engineering ,Nuclear reactor ,law.invention ,Core (optical fiber) ,Thermal hydraulics ,Electricity generation ,Nuclear Energy and Engineering ,Neutron flux ,Thermal radiation ,law ,General Materials Science ,Light-water reactor ,Safety, Risk, Reliability and Quality ,business ,Waste Management and Disposal - Abstract
The High Performance Light Water Reactor (HPLWR) is a thermal spectrum nuclear reactor cooled and moderated with light water operated at supercritical pressure. It is an innovative reactor concept, which requires developing and applying advanced analysis tools as described in the paper. The relevant water density reduction associated with the heat-up, together with the multi-pass core design, results in a pronounced coupling between neutronic and thermal-hydraulic analyses, which takes into account the strong natural influence of the in-core distribution of power generation and water properties. The neutron flux gradients within the multi-pass core, together with the pronounced dependence of water properties on the temperature, require to consider a fine spatial resolution in which the individual fuel pins are resolved to provide precise evaluation of the clad temperature, currently considered as one of the crucial design criteria. These goals have been achieved considering an advanced analysis method based on the usage of existing codes which have been coupled with developed interfaces. Initially neutronic and thermal-hydraulic full core calculations have been iterated until a consistent solution is found to determine the steady state full power condition of the HPLWR core. Results of few group neutronic analyses might be less reliable in case of HPLWR 3-pass core than for conventional LWRs because of considerable changes of the neutron spectrum within the core, hence 40 groups transport theory has been preferred to the usual 2 groups diffusion theory. Successively, with the usage of a developed pin-power reconstruction technique capable to account for the innovative fuel assembly design, sub-channel investigations of the individual fuel assemblies have been performed evaluating pin-wise clad temperatures. Obtained results will be discussed giving a detailed insight of the revolutionary HPLWR 3 pass core concept and understanding the physical reasons, which influence the local clad temperatures. The obtained results represent a new quality in core analyses, which takes into full consideration the coupling between neutronics and thermal-hydraulics as well as the spatial effects of the fuel assembly heterogeneity in determining the local pin-power and the associated maximum clad temperature.
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- 2011
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10. European supercritical water cooled reactor
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Eckart Laurien, Thomas Schulenberg, M. Ruzickova, Csaba Maráczy, Dietmar Bittermann, J.A. Lycklama à Nijeholt, Jörg Starflinger, P. Marsault, Aki Toivonen, Henryk Anglart, and Michele Andreani
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Nuclear and High Energy Physics ,Rankine cycle ,Engineering ,business.industry ,Mechanical Engineering ,Nuclear engineering ,Boiler feedwater ,Mechanical engineering ,Supercritical fluid ,Coolant ,law.invention ,Nuclear Energy and Engineering ,law ,Pressurizer ,Boiling water reactor ,General Materials Science ,Light-water reactor ,Safety, Risk, Reliability and Quality ,business ,Waste Management and Disposal ,Neutron moderator - Abstract
The High Performance Light Water Reactor (HPLWR), how the European Supercritical Water Cooled Reactor is called, is a pressure vessel type reactor operated with supercritical water at 25 MPa feedwater pressure and 500 °C average core outlet temperature. It is designed and analyzed by a European consortium of 10 partners and 3 active supporters from 8 Euratom member states in the second phase of the HPLWR project. Most emphasis has been laid on a core with a thermal neutron spectrum, consisting of small fuel assemblies in boxes with 40 fuel pins each and a central water box to improve the neutron moderation despite the low coolant density. Peak cladding temperatures of the fuel rods have been minimized by heating up the coolant in three steps with intermediate coolant mixing. The containment design with its safety and residual heat removal systems is based on the latest boiling water reactor concept, but with different passive high pressure coolant injection systems to cause a forced convection through the core. The design concept of the steam cycle is indicating the envisaged efficiency increase to around 44%. Moreover, it provides the constraints to design the components of the balance of the plant. The project is accompanied by numerical studies of heat transfer of supercritical water in fuel assemblies and by material tests of candidate cladding alloys, performed by the consortium and supported by additional tests of the Joint Research Centre of the European Commission. Besides the scientific and technical progress, the HPLWR project turned out to be most successful in training the young generation of nuclear engineers in the technologies of light water reactors. More than 20 bachelor or master theses and more than 10 doctoral theses on HPLWR technologies have been submitted at partner organizations of this consortium since the start of this project.
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- 2011
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11. Mixing of cooling water in the mixing chambers of the HPLWR—High Performance Light Water Reactor
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Alexander Wank, Jörg Starflinger, Thomas Schulenberg, and Eckart Laurien
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Nuclear and High Energy Physics ,Materials science ,Waste management ,business.industry ,Mechanical Engineering ,Nuclear engineering ,Computational fluid dynamics ,Supercritical fluid ,Coolant ,Nuclear Energy and Engineering ,Water cooling ,General Materials Science ,Light-water reactor ,Safety, Risk, Reliability and Quality ,business ,Waste Management and Disposal ,Superheater ,Mixing (physics) ,Evaporator - Abstract
The High Performance Light Water Reactor (HPLWR), a supercritical water cooled reactor concept with multiple heat-up steps, requires efficient mixing of the coolant between these steps to minimize hot spots in the core. Analyzing and improving the mixing in the mixing chamber above the core, situated between evaporator and superheater assemblies, and below the core, between the first and second superheater, is one of the challenges in the design process of the HPLWR. Different measures to enhance mixing have been studied with CFD analyses, in which a new design approach has been applied to the upper mixing chamber. It simplifies the complex structures and takes the effects of the disregarded structures into account by introducing source terms into the momentum equations.
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- 2010
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12. CORE DESIGN CONCEPTS FOR HIGH PERFORMANCE LIGHT WATER REACTORS
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T. Schulenberg and J. Starflinger
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Engineering ,Rankine cycle ,business.industry ,Nuclear engineering ,Pressurized water reactor ,Mixing (process engineering) ,Mechanical engineering ,Turbine ,Supercritical fluid ,Coolant ,law.invention ,Core (optical fiber) ,Nuclear Energy and Engineering ,Nuclear reactor core ,law ,business - Abstract
Light water reactors operated under supercritical pressure conditions have been selected as one of the promising future reactor concepts to be studied by the Generation IV International Forum. Whereas the steam cycle of such reactors can be derived from modem fossil fired power plants, the reactor itself, and in particular the reactor core, still need to be developed. Different core design concepts shall be described here to outline the strategy. A first option for near future applications is a pressurized water reactor with core exit temperature, having a closed primary loop and achieving 2% pts. higher net efficiency and 24% higher specific turbine power than latest pressurized water reactors. More efficiency and turbine power can be gained from core exit temperatures around , which require a multi step heat up process in the core with intermediate coolant mixing, achieving up to 44% net efficiency. The paper summarizes different core and assembly design approaches which have been studied recently for such High Performance Light Water Reactors.
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- 2007
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13. The SAMe-TT2R2 score and quality of anticoagulation in atrial fibrillation:a simple aid to decision-making on who is suitable (or not) for vitamin K antagonists
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Ding, Wern Yew, Potpara, Tatjana, Blomström‐lundqvist, Carina, Boriani, Giuseppe, Marin, Francisco, Fauchier, Laurent, Lip, Gregory, Lip, G.Y.H., Tavazzi, L., Maggioni, A., Dan, G‐a., Nabauer, M., Kalarus, Z., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., García Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K.A, Erglis, A., Poposka, L., Burg, M., Crijns, H., Erküner, Ö., Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zëra, E., Ekmekçiu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., Husseini, Z. El, Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., Genechten, G., Heidbuchel, H., Boussy, T., Coninck, M., Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., Hauwaert, B., Kuppens, C., Faes, D., Lier, D., Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska‐georgieva, S., Slavcheva, S., Yotov, Y., Kubíčková, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Venø, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castaño, S., Cheggour, S., Poulard, J., Mouquet, V., Leparrée, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassalière, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois‐jacquey, C., Kassim, H., Marijon, E., Le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden‐lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefèvre, M., Mingam, R., Haissaguerre, M., Le Bidan, M., Pavin, D., Le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer‐bouchard, C., da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Glöggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Köster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Förtsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Ländle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hötz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schön, B., Schön, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler‐schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., Di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V.L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum‐bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., Groot, J., Neefs, J., den Berg, N., Piersma, F., Wilde, A., Hagens, V., Es, J., Opstal, J., Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., Doorn, W., Szili‐torok, T., Bhagwandien, R., Janse, P., Muskens, A., Eck, M., Gevers, R., Der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch‐fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik‐sztylc, A., Czapla, W., Mróz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska‐filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor‐broda, M., Biedron, M., Gasior, Z., Kołodziej, M., Janion, M., Gorczyca‐michta, I., Wozakowska‐kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc‐dyl, E., Miarka, J., Pasieka, M., Ziemińska‐łuć, M., Bujak, W., Śliwiński, A., Grech, A., Morka, J., Petrykowska, K., Prasał, M., Hordyński, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Woźniak, P., Chlebuś, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kaźmierczak, J., Przybylska, A., Skorek, E., Błaszczyk, H., Stępień, M., Szabowski, S., Krysiak, W., Szymańska, M., Karasiński, J., Blicharz, J., Skura, M., Hałas, K., Michalczyk, L., Orski, Z., Krzyżanowski, K., Skrobowski, A., Zieliński, L., Tomaszewska‐kiecana, M., Dłużniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tymińska, A., Ozierański, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik‐lydka, A., Leopold‐jadczyk, A., Jedrzejczyk‐patej, E., Koziel, M., Mazurek, M., Krzemien‐wolska, K., Starosta, P., Nowalany‐kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandão Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragão, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhães, P., Fontes, P., Leão, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu‐andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Ioachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina‐ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Vukmirovic, L., Radisavljevic, M., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Radovanovic, S., Kocijancic, A., Obrenovic‐kircanski, B., Kalimanovska Ostric, D., Simic, D., Jovanovic, I., Petrovic, I., Polovina, M., Vukicevic, M., Tomasevic, M., Mujovic, N., Radivojevic, N., Petrovic, O., Aleksandric, S., Kovacevic, V., Mijatovic, Z., Ivanovic, B., Tesic, M., Ristic, A., Vujisic‐tesic, B., Nedeljkovic, M., Karadzic, A., Uscumlic, A., Prodanovic, M., Zlatar, M., Asanin, M., Bisenic, B., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Backovic, S., Stevanovic, A., Andric, A., Pencic, B., Pavlovic‐kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric‐cupic, V., Djordjevic, D., Damjanovic, M., Zdravkovic, S., Topic, V., Stanojevic, D., Randjelovic, M., Jankovic‐tomasevic, R., Atanaskovic, V., Antic, S., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Mijatovic, A., Tanasic, D., Radakovic, G., Peranovic, J., Panic‐jelic, N., Vujadinovic, O., Pajic, P., Bekic, S., Kovacevic, S., García Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldán Rabadan, I., Gil Ortega, M., Tello Montoliu, A., Orenes Piñero, E., Manzano Fernández, S., Romero Aniorte, A., Veliz Martínez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., García‐bolao, I., Bertomeu Gonzalez, V., Otero‐raviña, F., García Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil‐baron, P., Koç, M., Onrat, E., Dural, I., Yilmaz, K., Özin, B., Tan Kurklu, S., Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U.O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M., Kutlu, M., Demir, M., Gibbs, C., Kaminskiene, S., Bryce, M., Skinner, A., Belcher, G., Hunt, J., Stancombe, L., Holbrook, B., Peters, C., Tettersell, S., Shantsila, A., Senoo, K., Proietti, M., Russell, K., Domingos, P., Hussain, S., Partridge, J., Haynes, R., Bahadur, S., Brown, R., Mcmahon, S., Mcdonald, J., Balachandran, K., Singh, R., Garg, S., Desai, H., Davies, K., Goddard, W., Galasko, G., Rahman, I., Chua, Y., Payne, O., Preston, S., Brennan, O., Pedley, L., Whiteside, C., Dickinson, C., Brown, J., Jones, K., Benham, L., Brady, R., Buchanan, L., Ashton, A., Crowther, H., Fairlamb, H., Thornthwaite, S., Relph, C., Mcskeane, A., Poultney, U., Kelsall, N., Rice, P., Wilson, T., Wrigley, M., Kaba, R., Patel, T., Young, E., Law, J., Runnett, C., Thomas, H., Mckie, H., Fuller, J., Pick, S., Sharp, A., Hunt, A., Thorpe, K., Hardman, C., Cusack, E., Adams, L., Hough, M., Keenan, S., Bowring, A., Watts, J., Zaman, J., Goffin, K., Nutt, H., Beerachee, Y., Featherstone, J., Mills, C., Pearson, J., Stephenson, L., Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., Mckinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., Mckenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O’donohoe, L., Mozid, A., Dymond, H., Lloyd‐jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt‐kerby, T., Garnier, Sophie, Hengstenberg, Christian, Lamblin, Nicolas, Dubourg, Olivier, de Groote, Pascal, Trochu, Jean-Noël, Arbustini, Eloisa, Esslinger, Ulrike, Barton, Paul, Meder, Benjamin, Katus, Hugo, Frese, Karen, Komajda, Michel, Cook, Stuart, Isnard, Richard, Tiret, Laurence, Villard, Eric, Charron, Philippe, Angoulvant, D., University of Belgrade [Belgrade], Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), Océan du Large et Variabilité Climatique (OLVAC), Laboratoire d'études en Géophysique et océanographie spatiales (LEGOS), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), University of Liverpool, Aalborg University [Denmark] (AAU), Maria Cecilia Hospital [Cotignola], Valorex SAS, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Department of Internal Medicine II, Division of Respirology, University of Regensburg, Regensburg, Germany, Universität Regensburg (UR), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Ambroise Paré [AP-HP], Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), IRCCS - Pavia, Heidelberg University Hospital [Heidelberg], Université Pierre et Marie Curie - Paris 6 (UPMC), Robert Steiner MRI Unit, Imperial College London, Université de Montréal (UdeM), CHU Tenon [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
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Male ,medicine.medical_specialty ,Vitamin K ,MEDLINE ,Vitamin k ,Poor quality ,Decision Support Techniques ,[SHS]Humanities and Social Sciences ,Thromboembolism ,Physiology (medical) ,Internal medicine ,Atrial Fibrillation ,Humans ,Medicine ,In patient ,Blood Coagulation ,Stroke ,ComputingMilieux_MISCELLANEOUS ,Framingham Risk Score ,business.industry ,Anticoagulants ,Atrial fibrillation ,medicine.disease ,Surgery ,Cohort ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
This editorial refers to ‘Evaluation of SAMe-TT2R2 risk score for predicting the quality of anticoagulation control in a real-world cohort of patients with non-valvular atrial fibrillation on vitamin-K antagonists’ by M. R.R.-Y. Abumuaileq et al. , doi:10.1093/europace/euu353. Maintaining the therapeutic range in patients treated with vitamin K antagonists (VKAs) had always been challenging whilst the potential consequences of deviating from the optimal average time in therapeutic range(TTR) are deleterious in patients with atrial fibrillation (AF), given the risk for thromboembolic and bleeding events.1,2 Various clinical decision-making tools have been developed to help decision-making in the management of AF patients. In 2013, a new score—with the acronym SAMe-TT2R2—was proposed to help identify those patients who were likely to have a propensity to poor INR control (as reflected by average time in the therapeutic range [TTR] 2).3 This score was derived from a trial cohort and thus independent validation in ‘real-world’ AF cohorts would be needed. In the current issue of EP-Europace , Abumaileq et al. 4 performed a retrospective analysis of a cohort of outpatients with non-valvular AF and found that SAMe-TT2R2 could indeed represented a useful clinical tool to identify a poor quality of anticoagulation control with VKAs. The predictive ability of SAMe-TT2R2 was acceptable for identifying low TTR and improved when integrated with other clinical characteristics. A strong relationship …
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- 2015
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14. New Single Wafer Double Sided Spin Cleaning Method
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Hans-Jürgen Dipl.-Ing. Kruwinus, Reinhard Sellmer, Alfred Lechner, Jörg Leberzammer, Walter Starflinger, and Stefan Detterbeck
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Materials science ,business.industry ,Optoelectronics ,General Materials Science ,Nanotechnology ,Wafer ,Condensed Matter Physics ,business ,Atomic and Molecular Physics, and Optics ,Spin-½ - Published
- 2001
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15. Near Term Application of Supercritical Water Technologies
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Thomas Schulenberg, Joerg Starflinger, and Bastian Vogt
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Engineering ,Waste management ,business.industry ,Nuclear engineering ,Pressurized water reactor ,Boiler feedwater ,Supercritical fluid ,Power (physics) ,law.invention ,Volumetric flow rate ,Plant efficiency ,law ,Mass flow rate ,business ,Communication channel - Abstract
A pressurized water reactor with a supercritical water primary loop is analyzed (PWR-SC) within this paper. It will be shown that the PWR-SC offers considerable advantages in the fields of safety, economy and efficiency compared with a conventional PWR design. A cycle analysis shows that the net plant efficiency increases by 2% compared to currently operated or built systems. In addition, the mass flow rate of the primary side is strongly decreased, which enables a reduction of the primary pump power by a factor of 4. In the secondary loop, the mass flow rate can be decreased by about 15%, which allows downscaling of all secondary side components such as turbines, condensers and feed-water preheat systems as a consequence of the high core exit temperature. A coupled core analysis and a hot channel factor analysis are performed to demonstrate the promising safety features of the PWR-SC and to show the technical feasibility of such a system.Copyright © 2006 by ASME
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- 2006
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16. Effect of tibolone compared with sequential hormone replacement therapy on carbohydrate metabolism in postmenopausal women
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Beate Leifels-Fischer, Wolfgang Tetzloff, Inka Wiegratz, J. S. E. Dericks-Tan, Herbert Kuhl, Frans A Helmond, and Franz Starflinger
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Blood Glucose ,medicine.medical_specialty ,medicine.drug_class ,Hormone Replacement Therapy ,Norpregnenes ,medicine.medical_treatment ,Medrogestone ,Tibolone ,Carbohydrate metabolism ,General Biochemistry, Genetics and Molecular Biology ,Drug Administration Schedule ,chemistry.chemical_compound ,Estrogen Receptor Modulators ,Internal medicine ,Medicine ,Humans ,Insulin ,Netherlands ,Glucose tolerance test ,Estrogens, Conjugated (USP) ,medicine.diagnostic_test ,C-Peptide ,business.industry ,Obstetrics and Gynecology ,Hormone replacement therapy (menopause) ,Glucose Tolerance Test ,Middle Aged ,medicine.disease ,Menopause ,Postmenopause ,Endocrinology ,chemistry ,Estrogen ,Female ,business ,hormones, hormone substitutes, and hormone antagonists ,medicine.drug - Abstract
Objective: To investigate the effects of tibolone on carbohydrate metabolism, and to compare these effects with those of a sequential regimen of conjugated equine estrogens and medrogestone. Methods: This was an open-label, multicentre, comparative study. Seventy-two postmenopausal women were randomized to receive either tibolone 2.5 mg/day or conjugated equine estrogens 0.6 mg plus sequential medrogestone 5 mg (CEE/M) for six 28-day cycles. Carbohydrate metabolism was evaluated at baseline and after three and six cycles of treatment by an oral glucose tolerance test (OGTT). A blood sample was taken at 30, 60, 90 and 120 mm after glucose 75 mg dosing for determination of plasma glucose, insulin and connecting peptide (C-peptide) levels. Results: The changes from baseline of glucose, insulin and C-peptide area-under-the-curve (AUC) values were not statistically significant after 3 and 6 months of tibolone or CEE/M treatment. There was a small transitory decrease in HbA 1C after three cycles of treatment with tibolone. Conclusion: The effects of tibolone and CEE/M on carbohydrate metabolism were considered to have no clinical significance.
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- 2002
17. Matched pair analysis of survival after chest-wall recurrence compared to mammary recurrence: a long-term follow up
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Wolfgang Janni, T. Genz, T. Dimpfl, Naim Shabani, B. Lampe, U. Peschers, D. Rjosk, L. Starflinger, and F. Bergauer
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Oncology ,Cancer Research ,medicine.medical_specialty ,Multivariate analysis ,Skin Neoplasms ,Time Factors ,medicine.medical_treatment ,Matched-Pair Analysis ,Breast Neoplasms ,Metastasis ,Breast cancer ,Risk Factors ,Internal medicine ,medicine ,Humans ,Risk factor ,Lymph node ,Survival rate ,Mastectomy ,Proportional Hazards Models ,Observer Variation ,Univariate analysis ,Analysis of Variance ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Prognosis ,Survival Analysis ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Lymphatic Metastasis ,Female ,Neoplasm Recurrence, Local ,business ,Follow-Up Studies - Abstract
Background: Local recurrence remains a major concern after primary treatment of breast cancer and has a major impact on subsequent survival. While most studies report a poorer survival rate in patients with a local recurrence after mastectomy than after breast conservation, it remains controversial whether different risk profiles at the time of primary diagnosis may account for this difference. Method: Matched pair analysis of 134 patients with newly diagnosed locoregional recurrence of breast cancer without evidence of systemic disease. Matching criteria included the primary surgical treatment, tumor size, nodal status, and age. The significance of various prognostic parameters at the time of primary diagnosis and at the time of recurrence were evaluated, by univariate and multivariate analyses, with respect to survival after recurrence. The median follow-up was 8.4 years. Results: Risk factors at the time of presentation, such as tumor size and lymph node status, were comparable between both groups. Local recurrence occurred on an average 9 months earlier in patients after mastectomy (P=0.08). Univariate analysis showed that lymph node status (P=0.0001) and disease-free interval from primary treatment to local recurrence (P=0.0002) were the most significant single prognostic factors for subsequent survival after local recurrence. The primary surgical treatment modality was shown to be of marginal statistical influence (only P=0.05). Conclusion: Local recurrence after mastectomy seems to be associated with worse survival than after breast-conserving therapy. Early onset of chest-wall recurrence, moreover, represents the highest independent risk for cancer-associated death.
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- 2001
18. Matched pair analysis of survival after local recurrence in breast cancer patients after mastectomy vs. breast conservation: A long-term follow-up
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Wolfgang Janni, W. Sigg, T. Dimpfl, F. Bergauer, D. Rjosk, T. Genz, L. Starflinger, and Harald Sommer
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Oncology ,medicine.medical_specialty ,Matched Pair Analysis ,Breast conservation ,business.industry ,Long term follow up ,medicine.medical_treatment ,Obstetrics and Gynecology ,General Medicine ,medicine.disease ,Breast cancer ,Internal medicine ,medicine ,business ,Mastectomy - Published
- 2000
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19. [Untitled]
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W. Starflinger, T. Bolze, P. Kuepper, S. Roehl, H.G. Mohr, C. Diekmann, and B. Hasler
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Materials science ,business.industry ,Oxide ,Topology (electrical circuits) ,law.invention ,Capacitor ,chemistry.chemical_compound ,chemistry ,law ,Megabit ,Gate oxide ,Electronic engineering ,Optoelectronics ,Dry etching ,Reactive-ion etching ,business ,Dram - Abstract
A new completely selfaligned isolation oxide etch process prior to gate oxidation was developped with resulting gate oxide quality, isolation properties and topology comparable to a process with mask.
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- 1989
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20. Setup of the Supercritical CO2 Test Facility 'SCARLETT' for Basic Experimental Investigations of a Compact Heat Exchanger for an Innovative Decay Heat Removal System
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Rainer Mertz, Wolfgang Flaig, and Joerg Starflinger
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Radiation ,Materials science ,Supercritical carbon dioxide ,business.industry ,020209 energy ,Nuclear engineering ,02 engineering and technology ,021001 nanoscience & nanotechnology ,7. Clean energy ,Supercritical fluid ,Coolant ,Nuclear Energy and Engineering ,Waste heat ,Heat transfer ,Heat exchanger ,0202 electrical engineering, electronic engineering, information engineering ,Decay heat ,0210 nano-technology ,business ,Thermal energy - Abstract
Supercritical fluids show great potential as future coolants for nuclear reactors, thermal power, and solar power plants. Compared to the subcritical condition, supercritical fluids show advantages in heat transfer due to thermodynamic properties near the critical point. A specific field of interest is an innovative decay heat removal system for nuclear power plants, which is based on a turbine-compressor system with supercritical CO2 as the working fluid. In case of a severe accident, this system converts the decay heat into excess electricity and low-temperature waste heat, which can be emitted to the ambient air. To guarantee the retrofitting of this decay heat removal system into existing nuclear power plants, the heat exchanger (HE) needs to be as compact and efficient as possible. Therefore, a diffusion-bonded plate heat exchanger (DBHE) with mini channels was developed and manufactured. This DBHE was tested to gain data of the transferable heat power and the pressure loss. A multipurpose facility has been built at Institut für Kernenergetik und Energiesysteme (IKE) for various experimental investigations on supercritical CO2, which is in operation now. It consists of a closed loop where the CO2 is compressed to supercritical state and delivered to a test section in which the experiments are run. The test facility is designed to carry out experimental investigations with CO2 mass flows up to 0.111 kg/s, pressures up to 12 MPa, and temperatures up to 150 °C. This paper describes the development and setup of the facility as well as the first experimental investigation.
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21. 15 YEARS OF THE EUROPEAN NUCLEAR EDUCATION NETWORK (ENEN ASSOCIATION)
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Filip Tuomisto, Veronique Decobert, John Roberts, Jörg Starflinger, Pedro Dieguez Porras, Pascal Anzieu, Tzanny Kokalova Wheldon, Michèle Coeck, Behrooz Bazargan-Sabet, and Leon Cizelj
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Economic growth ,Nuclear industry ,business.industry ,Association (object-oriented programming) ,Political science ,Nuclear power ,business - Abstract
The European Nuclear Education Network (ENEN) was established in 2003 through an EU Fifth Framework Programme (FP) project, as a legal nonprofit-making body. Its main objective is the preservation and further development of expertise in the nuclear fields by higher education and training. This objective is realized through the cooperation between EU universities involved in education and research in nuclear disciplines, nuclear research centers and the nuclear industry. As of March 2018, ENEN has 66 members in 18 EU countries and has concluded Memoranda of Understanding (MoU) with partners beyond Europe for further cooperation, including organizations in, Russian Federation, Ukraine, Canada and Japan. ENEN also has good collaboration with national networks and international organizations such as the Belgian Nuclear Education Network (BNEN) and the International Atomic Energy Agency (IAEA). The main activities developed, and results achieved, within the first 15 years of the ENEN Association are presented and discussed. These include, for example, the launch of the European Master of Science in Nuclear Engineering (EMSNE), the annual ENEN Ph.D. competition and the portfolio of more than 10 EURATOM projects dealing with nuclear education, training and knowledge management through development of teaching methods and materials, courses, and exchange of students and teachers within EU and beyond. Those projects were all supported by the European Commission with the ENEN Association acting as the coordinator or as a partner.
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