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In this paper, a controlled quantum dialogue protocol is designed based on five-qubit entangled states. One five-qubit entangled state can be used to exchange one communicant’s two private bits with the other communicant’s two private bits under the control of an honest supervisor. Security analysis turns out that it can overcome the information leakage problem and can resist the active attacks from an outside attacker. The designed protocol only needs single-particle measurements and Bell state measurements, both of which can be realized with current technologies.

In this paper, we construct a semi-quantum dialogue (SQD) protocol by using Bell entangled states as the initial quantum resource. The information leakage problem is prevented by utilizing the entanglement correlation of two particles from one Bell entangled state. The security towards active attacks from an outside Eve is guaranteed by twice security checks and one classical one-time pad encryption process. The proposed SQD protocol can be realized in experiment with present quantum technologies. Compared with the traditional quantum dialogue (QD) protocols without information leakage, the advantage of the proposed SQD protocol lies in that it doesn’t require both communicants to possess quantum capabilities.

Hong-ming Pan,1,* Hong-ling Li,2,* Zhang-shun Shen,2 Hui Guo,2 Qian Zhao,2 Jian-guo Li2 1Graduate School of Hebei Medical University, Shijiazhuang, 050051, People’s Republic of China; 2Department of Emergency Medicine, Hebei General Hospital, Shijiazhuang, 050051, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-guo LiDepartment of Emergency Medicine, Hebei General Hospital, No. 348 Heping West Road, Shijiazhuang, 050051, People’s Republic of ChinaTel +86 31185988361Email li_jian_guo3@163.comObjective: The present study aimed to explore the effectiveness of the etiology checklist and process thinking in the differential diagnosis for acute abdominal pain.Methods: A retrospective design was used to include 5,403 patients with acute abdominal pain in the Emergency Department of Hebei Provincial People’s Hospital. The patients with acute abdominal pain between July and December 2017 in whom the etiology checklist and process thinking were not implemented were selected as the traditional group. Those with acute abdominal pain between July and December 2018 in whom the etiology checklist and process thinking were implemented were selected as the process thinking group. The clinical data, such as the emergency length of stay, hospitalization expenses, hospitalization length of stay, diagnostic accuracy, and outcome, were compared between the two groups.Results: For patients at emergency level 2 and above, the average emergency length of stay was shorter in the process thinking group than in the traditional group, while the average emergency length of stay was longer for patients at emergency level 3. For hospitalized patients at emergency level 2 and above and patients at emergency level 3, those in the process thinking group had improved diagnostic accuracy, shorter average hospitalization length of stay, reduced average hospital expenses, and improved outcomes. In the comparison among six physicians, the results in the traditional group were inconsistent and statistically different in terms of the average emergency length of stay and diagnostic accuracy, while the results in the process thinking group tended to be consistent. The differences were not statistically different.Conclusion: The diagnostic model for acute abdominal pain based on the etiology checklist and process thinking could improve the diagnostic accuracy and outcomes for patients with acute abdominal pain.Keywords: acute abdominal pain, emergency diagnosis, lateral thinking, process thinking

Background: Lymph node metastasis (LNM) of lung cancer is an important factor associated with prognosis. Dysregulated microRNAs (miRNAs) are becoming a new powerful tool to characterize tumorigenesis and metastasis. We have developed and validated a miRNA disease signature to predict LNM in lung adenocarcinoma (LUAD). Method: LUAD miRNAs and clinical data from The Cancer Genome Atlas (TCGA) were obtained and divided randomly into training (n = 259) and validation (n = 83) cohorts. A miRNA signature was built using least absolute shrinkage and selection operator (LASSO) (λ = -1.268) and logistic regression model. The performance of the miRNA signature was evaluated using the area under curve (AUC) of receiver operating characteristic curve (ROC). We performed decision curve analysis (DCA) to assess the clinical usefulness of the signature. We also conducted a miRNA-regulatory network analysis to look for potential genes engaged in LNM in LUAD. Result: Thirteen miRNAs were selected to build our miRNA disease signature. The model showed good calibration in the training cohort, with an AUC of 0.782 (95% CI: 0.725-0.839). In the validation cohort, AUC was 0.691 (95% CI: 0.575-0.806). DCA demonstrated that the miRNA signature was clinically useful. Conclusion: The miRNA disease signature can be used as a noninvasive method to predict LNM in patients with lung adenocarcinoma objectively and the signature achieved high accuracy for prediction.

Radiofrequency ablation (RFA) is a minimally invasive technology for the treatment of liver malignancies and is used as an adjuvant therapy in patients with colorectal liver metastasis (CLM). This study enrolled a total of 49 CLM patients who underwent RFA treatment. Univariate and multivariate analyses were performed using the log-rank test and Cox proportional hazard model, respectively. Univariate analysis showed that OS was closely correlated with tumor size, frequency of RFA treatment, resection of the liver lesion, and CEA levels before RFA (p p

AIM: To assess the catheterization-associated complications during intraperitoneal chemotherapy (IPCT) for advanced gastric cancer. METHODS: From 1998 to 2002, 80 patients with advanced gastric cancer received a total of 320 courses of IPCT using a large bore central venous catheter and associated complications were analyzed. RESULTS: Catheterization-associated complications occurred in 11 of the 80 patients (13.8%), including abdominal pain caused by catheter in 2 cases (0.63%), insertion failure in 2 cases (0.63%), bowel perforation in 1 case (0.31%) and abdominal pain during chemotherapy in 6 cases (1.88%). No serious complications required surgical intervention. CONCLUSION: IPCT using central venous catheters can be performed safely and simply without severe associated complications.