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1. Oral Research Presentations

Author

Hatice Gözde Akkın Gürbüz, Levent Turhan, Nilgun Şendil, Halim Ömer Kaşıkçı, Banu Salepçi, Derya Ipekcioglu, Canan Kuygun Karcı, Perihan Çam Ray, Ayşegül Yolga Tahiroğlu, Ayşe Avcı, Gonca Gül Çelik, Necmi Cekin, Nurdan Evliyaoğlu, Mehmet Alkanat, Hafize Özdemir, Egemen Akgün, Mehmet Emin Demirkol, Lut Tamam, Erman Esnafoglu, Doğa Sevinçok, Çağdaş Öykü Memiş, Bilge Doğan, Burcu Çakaloz, Ayşe Kutlu, Levent Sevinçok, Sema Nur Türkoğlu Dikmen, Yasir Şafak, Rıza Gökçer Tulacı, İlker Özdemir, Sema Baykara, Kübra Alban, Nazan Aydın, Hasan Mervan Aytaç, Doğan Yılmaz, Pınar Çetinay Aydın, Gökşen Yüksel Yalçın, Cana Canbay, Merve Terzioğlu, Aysel Özer, Ebru Altintas, Meryem Özlem Kütük, Ali Evren Tufan, Harika Gözükara Bağ, Güliz Şenormancı, Oya Güçlü, Cemil Çelik, Abdullah Bolu, Taner Öznur, Mehmet Sinan Aydın, Yusuf Tokgöz, Özcan Uzun, Sakır Gıca, Burç Çağrı Poyraz, Yağmur Sever Fidan, Hüseyin Güleç, Erdoğdu Akça, Mesut Yıldız, Zeynep Nur Demirok Akça, Yusuf Öztürk, Gonca Özyurt, Kadir Özdel, Gulcin Elboga, Muhammet Berkay Ozyurek, Abdullah Akgün, Ali Coşkun, Ayhan Bilgiç, Rukiye Çolak Sivri, İbrahim Kılınç, Ahmet İnal, Uğur Eray, Murat Acat, Arif Önder, Aslı Sürer Adanır, Canem Kavurma, Öznur Bilaç, Yakup Doğan, Rukiye Ay, Çağatay Uğur, Betül Gül Alıç, Mehmet Gündüz, Özlem Ünal, Ömer Uçur, Özlem Özcan, Hasret Karabulut Gül, Demet Sağlam Aykut, Ahmet Tiryaki, Filiz Civil Arslan, Gül Alkan Bülbül, Ömer Yolcu, Aysel Uysal, Esin Özatalay, Selma Cırrık, Esin Erdogan, Dursun Hakan Delibas, Hazan Tomar Bozkurt, Rukiye Tekdemir, Vefa Erbasan, Okan İmre, Memduha Aydın, Kürşat Altınbaş, Başak Karabucak, Halime Tuna Çak Esen, Sadriye Ebru Çengel Kültür, Remzi Karaokur, Songül Atasavun Uysal, Nurhan Erbil, Meltem Çiğdem Kirazlı, Tayfun Kara, Ajda Mutlu Mıhçıoğlu, Semra Yılmaz, İsmail Akaltun, Abdullah Atli, Zübeyir Can, Emine Füsun Akyüz Çim, Aslıhan Okan İbiloğlu, Nilfer Şahin, Hülya Ertekin, Zehra Başar Kocagöz, Adnan Özçetin, Ahmet Ataoğlu, Şengül Cangür, Safiye Bahar Ölmez, Neslihan Yazar, Halit Necmi Uçar, Duygu Murat, Şafak Eray, Yaşar Tanır, Hatice Altun, Mehmet Hanifi Tanyeri, Mehmet Emin Büyükokuroğlu, Pelin Tanyeri, Oguz Mutlu, Füruzan Yıldız Akar, Güner Ulak, Bekir Faruk Erden, Feyza Hatice Sevgen, Asiye Arıcı, Fethiye Kılıçaslan, Mehmet Fatih Erbay, Cengiz Darılmaz, Fikret Poyraz Çökmüş, Serra Yüzeren, Didem Sücüllüoğlu Dikici, Orkun Aydın, Pınar Ünal Aydın, Fatma Akdeniz, Siğnem Öztekin, Emine Özge Çöldür, Kuzeymen Balıkçı, Ertuğrul Köroğlu, Ömer Aydemir, Hüseyin Kara, Özgen Özçelik, Mehmet Murat Balcı, Mehmet Murat Kuloğlu, Talya Tomar, Fatma Taneli, Arzu Oran, Gülgün Yılmaz Ovalı, Gamze Yapça Kaypaklı, Özge Metin, Hakan Karaş, Halil Çetingök, Reşat İlişer, Elif Çarpar, Muzaffer Kaşer, Güneş Şayan Can, Gözde Ulaş, Ayşegül Ildız, Neslihan Emiroğlu, Emel Ada, Ayşegül Özerdem, Okan Imre, Oğuz Mutlu, Furuzan Yıldız Akar, Uğur Tekin, Ayşegül Satar, Ayşe Nur Aydın, Hatice Serpil Erermiş, Orhan Kocaman, Nihal Yurteri Çetin, Aynur Akay, Yüksel Sümeyra Karagöz, Özlem Doğan, Serenay Ülkar, Birim Günay Kılıç, Hacer Akgül Ceyhun, Esat Fahri Aydın, Tuba Ülkevan, Nilifer Gürbüzer, Hasan Cem Aykutlu, Işık Görker, Emel Özen, Evrim Aktepe, Mustafa Asım Aydın, Dudu Dilek Yavuz, Umut Karaaslan, Abdullah Karataş, Zehra Sancak, Erhan Eser, Mehmet Murat Demet, Mehmet Emrah Karadere, Ece Yazla Asafov, Halil İbrahim Ölçüm, Ayhan Algül, İbrahim Gündoğmuş, Fatih Hilmi Cetin, Hasan Ali Guler, Serhat Turkoglu, Bahar Keleş Çolpan, Elif Bayram, Funda Seher Özalp Ateş, Serap Tıraş Teber, Nagihan Saday Duman, Emel Sarı Gökten, Elif Nurgül Sungur, Melike Ceyhan Balcı Şengül, Ayşen Çetin Kardeşler, Yaşar Enli, Neslihan Kurtul, Cihan Aslan, Bahadır Konuşkan, Burçin Şener, Banu Anlar, Fatih Ünal, Bülent Devrim Akçay, Güray Koç, Sinan Yetkin, Serkan Bayad, Müge Elbir, Özge Alp Topbaş, Tuğba Kocabaş, Adem Aydın, Pelin Avcu Çelik, Deniz Argüz Çıldır, Aylin Özbek, Aybuke Tuğçe Mustan, Ayşe Sevgi Karadağ, Aysun Kalenderoğlu, Mehmet Hamdi Örüm, Murat Eren Özen, Oğuzhan Bekir Eğilmez, Dilek Bingöl Aydın, Bahri Elmas, Serhat Nasıroğlu, Engin Aydın, Öner Özdemir, Özcan Erel, Ülker Fedai, Mehmet Asoğlu, Rümeysa Yeni Elbay, Hasan Turan Karatepe, Celal Ulaşoğlu, Hamza Ayaydın, Berkan Şahin, Koray Karabekiroğlu, Abdullah Bozkurt, Miraç Barış Usta, Muazzez Aydın, Cansu Çobanoğlu, Yalçın Kahya, Dilara İnan, Ali Ercan Altınöz, Ferdi Köşger, Altan Eşsizoğlu, Mehmet Arslan, Ali Metehan Çalışkan, Duygu Göktaş, İkbal İnanlı, Saliha Çalışır, İbrahim Eren, Zeynep Baran Tatar, Erhan Kurt, Gokhan Unal, Feyza Aricioglu, Mustafa Esad Tezcan, Tuğba Kalyoncu, Fazilet Ergüvendi, Çigdem Yektaş, Recep Eroz, Gokhan Yurdakul, Mahmut Cakır, Mehmet Yalcin Tasmektepligil, Saliha Baykal, Mirac Barıs Usta, Melih Nuri Karakurt, Koray Karabekiroglu, Yasemin Yulaf, Funda Gümştaş, Sebla Gökçe, Yankı Yazgan, Doğa Sevincok, Tugba Kalyoncu, Fazilet Arkat Ergüvendi, İbrahim Yağcı, Sema Avcı, Yüksel Kıvrak, Alişan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yılmaz Çetinkaya, Anıl Gündüz, Hülya Tireli, Kemal Utku Yazici, Ipek Percinel Yazici, Pınar Aksu Kılıçle, Süleyman Gül, Ipek Percınel Yazici, Ayçin Darıcı Sümer, Esra Çöp, Duygu Bilgili, Müge Şahin, Gülser Şenses Dinç, Özlem Hekim, Emine Dibek Mısırlıoğlu, Funda Kurt, Zeynep Göker, Özden Üneri, Eray Atalay, İrem Yıldırım, Ali İnaltekin, Bengü Yücens, Vahap Ozan Kotan, Nihal Özkayar, Fatih Dede, Rabia Nazik Yüksel, Şenol Bayram, Zeynep Kotan, Erol Göka, Gökçe Nur Say, Merve Kalyoncu, Özlem Beğinoğlu, Bahadir Bilgin Basgoz, Semra Ince, Umut Safer, and İlker Tasci

Subjects
medicine.medical_specialty, business.industry, health care facilities, manpower, and services, Addiction, media_common.quotation_subject, education, Neurosciences. Biological psychiatry. Neuropsychiatry, humanities, Child and adolescent, Psychiatry and Mental health, Cigarette smoking, International congress, Medicine, Pharmacology (medical), Psychopharmacology, business, Psychiatry, health care economics and organizations, RC321-571, media_common
Abstract

10th International Congress on Psychopharmacology & 6th International Symposium on Child and Adolescent Psychopharmacology[Abstract:0110] [Addiction]Cessation of cigarette smoking in adolescents: s...

Published
2018

2. Basal blood DHEA-S/cortisol levels predicts EMDR treatment response in adolescents with PTSD

Author

Berkan Şahin, Koray Karabekiroglu, Yusuf Yasin Gumus, Miraç Barış Usta, Abdullah Bozkurt, Gökçe Nur Say, and Ondokuz Mayıs Üniversitesi

Subjects
Male, Hypothalamo-Hypophyseal System, endocrine system, medicine.medical_specialty, Treatment response, Adolescent, Eye Movement Desensitization Reprocessing, Hydrocortisone, Pituitary-Adrenal System, cortisol, EMDR, Stress Disorders, Post-Traumatic, 03 medical and health sciences, Basal (phylogenetics), 0302 clinical medicine, Predictive Value of Tests, Internal medicine, medicine, Humans, In patient, DHEA, Child, Cortisol level, Depressive Disorder, Major, Dehydroepiandrosterone Sulfate, business.industry, food and beverages, PTSD, Biomarker, 030227 psychiatry, Psychiatry and Mental health, Treatment Outcome, Endocrinology, Adolescent Behavior, adolescent, Biomarker (medicine), Female, business, Biomarkers, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery
Abstract

Sahin, Berkan/0000-0003-4699-3418; Usta, Mirac Baris/0000-0002-1573-3165 WOS: 000424948600002 PubMed: 29171317 Objective: In literature, recent evidence has shown that the hypothalamic-pituitary-adrenal (HPA) axis can be dysregulated in patients with post-traumatic stress disorder (PTSD) and HPA axis hormones may predict the psychotherapy treatment response in patients with PTSD. In this study, it was aimed to investigate changing cortisol and DHEA-S levels post-eye movement desensitization and reprocessing (EMDR) therapy and the relationship between treatment response and basal cortisol, and DHEA-S levels before treatment.Method: The study group comprised 40 adolescents (age, 12-18 years) with PTSD. The PTSD symptoms were assessed using the Child Depression Inventory (CDI) and Child Post-traumatic Stress Reaction Index (CPSRI) and the blood cortisol and DHEA-S were measured with the chemiluminescence method before and after treatment. A maximum of six sessions of EMDR therapy were conducted by an EMDR level-1 trained child psychiatry resident. Treatment response was measured by the pre- to post-treatment decrease in self-reported and clinical PTSD severity.Results: Pre- and post-treatment DHEA-S and cortisol levels did not show any statistically significant difference. Pre-treatment CDI scores were negatively correlated with pre-treatment DHEA-S levels (r: -0.39). ROC analysis demonstrated that the DHEA-S/cortisol ratio predicts treatment response at a medium level (AUC: 0.703, p: .030, sensitivity: 0.65, specificity: 0.86).Conclusion: The results of this study suggested that the DHEA-S/cortisol ratio may predict treatment response in adolescents with PTSD receiving EMDR therapy. The biochemical parameter of HPA-axis activity appears to be an important predictor of positive clinical response in adolescent PTSD patients, and could be used in clinical practice to predict PTSD treatment in the future. Ondokuz Mayis UniversityOndokuz Mayis University [PYO.TIP.1904.16.002] The present study was sponsored by Ondokuz Mayis University with the project number PYO.TIP.1904.16.002.

Published
2017

3. Perinatal and medical risk factors in children with attention deficit hyperactivity disorder, autism spectrum disorder or specific learning disorder: comparison between diagnostic groups

Author

Koray Karabekiroglu, Abdullah Bozkurt, Berkan Şahin, Şahin, Berkan, and OMÜ

Subjects
medicine.medical_specialty, Attention Deficit Hyperactivity Disorder, business.industry, Autism Spectrum Disorder, lcsh:R, Developmental Characteristics, lcsh:Medicine, autism spectrum disorder, medicine.disease, behavioral disciplines and activities, developmental characteristics, attention deficit hyperactivity disorder, Medical risk, Autism spectrum disorder, Risk Factors, mental disorders, Specific Learning Disorder, Medicine, Attention deficit hyperactivity disorder, risk factors, business, Psychiatry
Abstract

Bozkurt, abdullah/0000-0002-8359-6131; Sahin, Berkan/0000-0003-4699-3418 WOS: 000502778500004 Introduction: Epigenetic changes in the pathogenesis of neurodevelopmental disorders, including prenatal and early life exposures, are becoming as appealing as hereditary genes. This study aimed to investigate possible pre-pubertal environmental and developmental risk factors for children with Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Specific Learning Disorder (SLD). Methods: The study included 98 children (24 ADHD, 24 SLD, 26 ASD, 20 controls) aged 7-12 years. The diagnostic evaluation was based on the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders and Schedule for Affective Disorders and Schizophrenia for School-age Children-present version. Parents completed socio-demographic data form for clinical evaluation, and The Wechsler Children's Intelligence scale was used to assess cognitive skills. Results: In our study, low parental education level, parental unemployment, low-income, and history of psychiatric disorders in first-degree relatives were associated with SLD risk, prematurity, and early self-regulation difficulties were associated with ASD risk, and history of allergy was associated with ADHD risk. Conclusion: In this study, the presence of many different risk factors that play a possible role in neurodevelopmental disorders suggests that further epigenetic studies arc needed.

Published
2019

4. Examination of Neutrophil, Platelet, Monocyte-Lymphocyte Ratios in Adolescents with Bipolar Disorder-Manic Episode and Depression

Author

Miraç Barış Usta, Abdullah Bozkurt, Armagan Aral, Koray Karabekiroglu, Berkan Şahin, OMÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk ve Ergen Ruh Sağlığı Hastalıkları Ana Bilim Dalı, and Şahin, Berkan

Subjects
Inflammation, Bipolar Disorder, Depression, Bipolar disorder, white blood cells, business.industry, Monocyte, Lymphocyte, fungi, medicine.disease, body regions, White Blood Cells, Psychiatry and Mental health, medicine.anatomical_structure, inflammation, mental disorders, depression, Immunology, Medicine, Platelet, Neurology (clinical), business, Depression (differential diagnoses)
Abstract

WOS: 000504845000007 Objective: Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) are practical inflammation parameters. In bipolar disorder (BD) and major depressive disorder (MDD), these parameters were reported higher than in healthy controls (HC). We aim to compare NLR, PLR, MLR in HC and patients with MDD and BB-manic episode. Method: Forty-six patients with MDD and 43 patients with BD hospitalized between 2013 and 2017 and 40 HC were included in the study. White blood cell, neutrophil, lymphocyte, platelet, and monocyte numbers were entered retrospectively from complete blood counts made at the time of admission, and NLR, PLR, and MLR were calculated from these. Results: NLR and PLR were revealed higher in MDD than HC. NLR and neutrophil values were higher in BD than HC, and there was a positive correlation between NLR and hospitalization period of patients with BD. Conclusion: Findings of our study supported the inflammation hypothesis for MDD and BD in adolescents. Larger-scale studies are necessary to confirm these findings.

Published
2019

5. Use of machine learning methods in prediction of short-term outcome in autism spectrum disorders

Author

Berkan Şahin, Cansu Cobanoglu, Neriman Kesim, Abdullah Bozkurt, Tolga Karaosman, Koray Karabekiroglu, Emre Ürer, Ayşegül Duman Kurt, Muazzez Aydın, Miraç Barış Usta, Armagan Aral, İrem Şahin, and OMÜ

Subjects
Autism, autism, Neurosciences. Biological psychiatry. Neuropsychiatry, behavioral disciplines and activities, Outcome (game theory), 03 medical and health sciences, 0302 clinical medicine, predictive measures, mental disorders, medicine, 0501 psychology and cognitive sciences, Pharmacology (medical), business.industry, 05 social sciences, medicine.disease, Term (time), Psychiatry and Mental health, machine learning, prognosis, Core symptoms, business, 030217 neurology & neurosurgery, RC321-571, 050104 developmental & child psychology, Clinical psychology
Abstract

Usta, Mirac Baris/0000-0002-1573-3165; Sahin, Berkan/0000-0003-4699-3418 WOS: 000481832500012 OBJECTIVE Studies show partial improvements in some core symptoms of Autism Spectrum Disorders (ASD) in time. However, the predictive factors (e.g. pretreatment IQ, comorbid psychiatric disorders, adaptive, and language skills, etc.) for a better the outcome was not studied with machine learning methods. We aimed to examine the predictors of outcome with machine learning methods, which are novel computational methods including statistical estimation, information theories and mathematical learning automatically discovering useful patterns in large amounts of data. METHOD The study the group comprised 433 children (mean age: 72.3 +/- 45.9 months) with ASD diagnosis. The ASD symptoms were assessed by the Autism Behavior Checklist, Aberrant Behavior Checklist, Clinical Global Impression scales at baseline (T0) and 12th (T1), 24th (T2), and 36th (T3) months. We tested the performance of for machine learning algorithms (Naive Bayes, Generalized Linear Model, Logistic Regression, Decision Tree) on our data, including the 254 items in the baseline forms. Patients with

Published
2019

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