Back to Search
Start Over
Examination of Neutrophil, Platelet, Monocyte-Lymphocyte Ratios in Adolescents with Bipolar Disorder-Manic Episode and Depression
- Source :
- Dusunen Adam: The Journal of Psychiatry and Neurological Sciences.
- Publication Year :
- 2019
- Publisher :
- Kare Publishing, 2019.
-
Abstract
- WOS: 000504845000007 Objective: Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) are practical inflammation parameters. In bipolar disorder (BD) and major depressive disorder (MDD), these parameters were reported higher than in healthy controls (HC). We aim to compare NLR, PLR, MLR in HC and patients with MDD and BB-manic episode. Method: Forty-six patients with MDD and 43 patients with BD hospitalized between 2013 and 2017 and 40 HC were included in the study. White blood cell, neutrophil, lymphocyte, platelet, and monocyte numbers were entered retrospectively from complete blood counts made at the time of admission, and NLR, PLR, and MLR were calculated from these. Results: NLR and PLR were revealed higher in MDD than HC. NLR and neutrophil values were higher in BD than HC, and there was a positive correlation between NLR and hospitalization period of patients with BD. Conclusion: Findings of our study supported the inflammation hypothesis for MDD and BD in adolescents. Larger-scale studies are necessary to confirm these findings.
- Subjects :
- Inflammation
Bipolar Disorder
Depression
Bipolar disorder
white blood cells
business.industry
Monocyte
Lymphocyte
fungi
medicine.disease
body regions
White Blood Cells
Psychiatry and Mental health
medicine.anatomical_structure
inflammation
mental disorders
depression
Immunology
Medicine
Platelet
Neurology (clinical)
business
Depression (differential diagnoses)
Subjects
Details
- ISSN :
- 10188681
- Database :
- OpenAIRE
- Journal :
- Dusunen Adam: The Journal of Psychiatry and Neurological Sciences
- Accession number :
- edsair.doi.dedup.....ff71b319c8ede10107fae5848b7e5728