Search

Highlights • Penile necrosis by calciphylaxis is a rare disease. • The diagnosis of CUA is often difficult. • The Management of this rare condition is still a matter of debate., Introduction Penile calciphylaxis is a rare disease whose diagnosis is not easy. It is associated with chronic renal failure. It is a result of media calcification and blood vessels’ fibrosis such as penile arteries that eventually lead to gangrene formation in extremities and penis. Calcific uremic arteriolopathy is commonly associated with secondary hyperparathyroidism and high level of calcium and phosphate. Presentation of case In this paper, we report a case of penile necrosis induced by calciphylaxis associated with chronic renal failure and diabetic macroangiopathy. We performed a partial and total amputation in two stages because of the wound infection. The patient died one week after a total penectomy. Discussion The skin biopsy is the gold standard for the diagnosis despite being a risky process. In most cases, appropriate medical management is advocated. The treatment of this pathology is still controversial. Conclusion The management of this rare situation is controversial, and its diagnosis is still difficult due to the scarcity of reported cases.

Solitary extramedullary plasmacytoma (EMP) involving the adrenal gland is an extremely rare malignancy. We report a case of a solitary adrenal plasmacytoma in an HIV-positive 50-year-old woman on antiretroviral therapy who presented with a rapidly progressing lumbar left masse. A CT scan objectified a locally advanced left adrenal mass measuring 135mm long axis. A biopsy was taken, and the histopathology with the immunohistochemical study objectified an adrenal gland plasmacytoma. The skeletal survey and the sternal suction biopsy did not show any abnormalities. The diagnosis of a solitary EMP of the adrenal gland was made. There are only 10 cases of solitary adrenal plasmacytoma with only one case associated with an HIV-positive patient reported in the literature. Therefore, this paper is aimed at presenting the second case of an HIV-positive patient diagnosed with solitary adrenal plasmacytoma.

We report the first case of a 52-year-old nondiabetic male admitted for management of uremic syndrome associated with emphysematous pyelonephritis (EPN), renal and perinephric abscess, and emphysematous cystitis (EC) on a single functional kidney with a large abundance of spontaneous pneumomediastinum (SP) complicating a SARS-CoV-2 pneumonia. The patient has benefited from several dialysis sessions, intravenous antibiotics, and percutaneous drainage. His clinical course was complicated by acute respiratory distress syndrome, and unfortunately, he died nine days following admission.

Most cases of bladder rupture are traumatic. Spontaneous rupture is much more rare, especially the one due to emphysematous cystitis (EC) which has been reported in only ninth cases in the literature. In our case, we report a 45 years old paraplegic patient with emphysematous cystitis and bladder rupture due to a urinary retention which causes him a urinary peritonitis treated with emergency laparotomy for repairing the wall of the bladder and antibiotics.

La tumeur de Buschke-Löwenstein appartient au groupe des carcinomes verruqueux. Plus fréquente chez les hommes et les immunodéprimés, elle se développe au niveau génital ou péri-anal, réalisant une volumineuse lésion bourgeonnante parfois ulcérée ou fistulisée aux organes voisins. L´histologie est proche de celle d´un condylome acuminé, avec cependant une prolifération plus marquée et une pénétration profonde dans les tissus adjacents mais sans rupture de la membrane basale. Une infection par Human papillomavirus (HPV) 6 et 11 est volontiers associée à ces tumeurs. La recherche d´autres infections sexuellement transmissibles associées est nécessaire. Un examen clinique rigoureux et une imagerie complémentaire permettent d´établir un bilan lésionnel précis. Le traitement est avant tout chirurgical, et doit être large du fait du haut potentiel récidivant de la tumeur. Des traitements néoadjuvants à type de chimiothérapie ou immunothérapie mériteraient d´être mieux évalués pour limiter le caractère délabrant de la chirurgie.

Adrenal myelolipoma (MLS) is a rare, benign and non-functional neoplasm, composed of adipose tissue and myeloid. We report a rare case of adrenal myelolipoma of a 20-year-old female revealed with chronic abdominal pain. Computed tomography (CT) scan of the abdomen guided diagnosis and surgical resection was performed given symptomatic and bulky mass. Histological examination confirmed the diagnosis. At 18 months after the surgery, the patient had no evidence of recurrence. The diagnosis of MLS is radiological. Therapeutic abstention is the rule for a small, asymptomatic tumor. The surgical removal is indicated when it is bulky (exceeds 7cm), symptomatic or hormonal activity.

Usual location of metastasis are in renal cell carcinoma (RCC) the lung, liver, bone, adrenal and brain. Here we report on an unusual case of a 76-year-old male with a solitary sternal metastasis as an initial presentation of clear-cell RCC. The management of metastatic kidney cancer has been disrupted over the last decade by the emergence of new treatments and the progress of surgery and ablative techniques. the Carmena study suggests that sunitinib alone is not inferior to the NCR followed by sunitinib, the patient has therefore been transferred to oncology for medical treatment (targeted therapy).

Bladder cancers are not very common in young people under 20 years, especially with an atypical presentation such as faecaluria due to enterovesical fistula.This report describes the case of a 20 years old man who was diagnosed with a mass involving the small intestine and bladder during the course of investigations for faecaluria and abdominal pain. Histopathological examination of the biopsies during cystoscopy revealed: muscle invasive transitional cell carcinoma, while the computerized tomography scan had confirmed the enterovesical fistula.The patient was traited by Radical cystectomy with extended pelvic lymph node dissection and ileocecal resection as ultimate curative treatment. Keywords: Entero-vesical fistula, Bladder cancer, Muscle invasive, Young adult, Crohn disease