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1. The Relevance of English: Teaching That Matters in Students' Lives. Refiguring English Studies.

Author

National Council of Teachers of English, Urbana, IL., Yagelski, Robert P., Leonard, Scott A., Yagelski, Robert P., Leonard, Scott A., and National Council of Teachers of English, Urbana, IL.

Abstract

An effort to contribute to the "story" of English teaching in the United States at the dawn of the new millennium, this book presents 17 essays that tell diverse and complex stories of the value and difficulty of teaching English. The voices in this volume represent an eclectic rather than a comprehensive group of teachers and scholars, some familiar, some perhaps less so, who draw from their experiences in secondary and postsecondary English classrooms to examine the question of the relevance of their work to the lives of their students. After an introduction: "The (Ir)relevance of English at the Turn of the Millennium" (Robert P. Yagelski), essays in Section I, Contexts: American Culture and the Study of English, are: (1) "The Academic Language Gap" (Gerald Graff); (2) "When the Multicultural Leaves the Race: Some Common Terms Reconsidered" (Victor Villanueva); (3) "It's Not an Economy, Stupid! The Education-as-Product Metaphor as Viewed from the English Classroom" (Scott A. Leonard); (4) "Literacy, Gender, and Adolescence: School-Sponsored English as Identity Maintenance" (Margaret J. Finders); (5) "On the Business of English Studies" (Stephen M. North); and "Exchange: Economies, Politics, and English Studies" (Finders, North, Leonard, and Villanueva). Essays in Section II, Changes: English Classrooms in an Evolving World, are: (6) "The High School English Teacher: A Relevant Member in a Good Tribe" (Donald L. Tinney); (7) "Promoting a Relevant Classroom Literacy: Personal Growth and Communal Action in a Middle Grades Curricular Development Project" (Sarah Robbins, with Mary Miesiaszek and Beth Davis); (8) "Women in Mind: The Culture of First-Year English and the Nontraditional Returning Woman Student" (Patricia Shelley Fox); (9) "Community College English: Diverse Backgrounds, Diverse Needs" (Kathleen R. Cheney); (10) "The Relevance of Paulo Freire on Liberatory Dialogue and Writing in the Classroom" (Christina Kirklighter); (11) "Surviving Intact: African American Women Negotiating Scholarly Identities through Graduate School Writing" (Juanita Rodgers Comfort); and "Exchange: Literacy, Classrooms, and Students' Lives" (Fox, Tinney, Kirklighter, Cheney, Robbins, Comfort). Essays in Section III, Futures: English Studies for the New Millennium, are: (12) "The Future of English Studies Made Personal, or, The Subversive Act of Teaching Well" (Valerie Hardin Drye); (13) "Cybrarians and Scholars in the New English Classroom" (Ted Nellen); (14) "The Past and Future of (Two-Year) College English Studies" (Mark Reynolds); (15) "Enacting Cultures: The Practice of Comparative Cultural Study" (Paula Mathieu and James J. Sosnoski); (16) "Critical Technological Literacy and English Studies: Teaching, Learning, and Action" (Richard J. Selfe and Cynthia L. Selfe); (17) "The Plural Commons: Meeting the Future of English Studies" (Kathleen Blake Yancey); and "Exchange: Language, Technology, and the Future of English Studies" (Drye, Reynolds, Mathieu, Sosnoski, R. Selfe, and Yancey). Contains an afterword by Richard M. Ohmann. (RS)

Published
2002

2. Channels of Propaganda.

Author

ERIC Clearinghouse on Reading, English, and Communication, Bloomington, IN. and Sproule, J. Michael

Abstract

Defining propaganda as "efforts by special interests to win over the public covertly by infiltrating messages into various channels of public expression ordinarily viewed as politically neutral," this book argues that propaganda has become pervasive in American life. Pointing out that the 1990s society is inundated with propaganda from numerous sources (including government, business, researchers, religious groups, the news media, educators, and the entertainment industry) the book exposes these channels of propaganda and the cumulative effect they have on public opinion and the functioning of American democracy. Chapter 1 reviews materials on diverse vantage points from which American writers and opinion leaders have tried to reconcile mass persuasion with the democratic way of life during the 20th century. Chapters 2-6 examine propaganda in: (1) government (e.g., Federal Bureau of Investigation, aid to the Contras, Star Wars, presidential styles); (2) research and religion (e.g., national security, private sector, religion and politics); (3) news (e.g., getting good coverage, pressure groups, and business); (4) classroom (e.g., business propaganda, pressure groups, textbooks, pressures on teachers); and (5) entertainment (e.g., film, television). Chapters 7 and 8 question: (1) what action a democratic people should take to safeguard intelligent discussion and free choice from the taint of devious communication; (2) to what extent propaganda casts a shadow over public life; and (3) whether large-scale, engineered persuasion can ever be squared with the ideal of democratic public deliberation. Extensive chapter notes and an index are included. (NKA)

Published
1994

3. An Empirical Study of Gift Authorships in Business Journals

Author

Manton, Edgar J. and English, Donald E.

Abstract

The authors surveyed authors of business journal articles who had worked with coauthors at 30 colleges of business, regarding their experience with gift or undeserved authorships. Of 433 responding faculty authors, more than 35% reported having collaborated with a coauthor who had done very little work on a published article, and nearly 10% responded that they had a coauthor on a publication who had done no work. Of respondents, 95% reported collaborating with a coauthor in the same discipline. Of the authors, 66% indicated having worked with a coauthor in another business discipline, and about 33% stated that they had collaborated with a coauthor from a discipline external to business. (Contains 5 tables.)

Published
2008
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4. Reasons for Co-Authorship in Business Journals and the Extent of Guest or Gift Authorships

Author

Manton, Edgar J. and English, Donald E.

Abstract

Faculty members at fifteen small to mid-sized colleges of business in Texas were surveyed to determine their views and experiences regarding publishing academic journal articles with multiple authors. Respondents indicated that the AACSB scholarly productivity standards have had an impact on their publication efforts and that they have published journal articles with co-authors. The main reasons for co-authoring were to work with someone from the same discipline for broader coverage or the need to add a person to a project who had knowledge from another discipline. Thirty-six percent of the respondents reported working with another author who had done very little work on a publication, and 18.5% cited working with co-authors who actually contributed nothing towards the effort to publish an article. A majority of the respondents indicated that the person doing the most work should be identified as the first author. (Contains 5 tables.)

Published
2006

5. A New Era: The Modernization of Cosmetics Regulation Act of 2022: Here's what you need to know about the statute's requirements, what to expect, and how to prepare

Author

Harrison, Todd and English, Melanie

Subjects
United States. Food and Drug Administration -- Laws, regulations and rules, Government regulation of business -- Methods, Regulatory compliance -- Laws, regulations and rules -- Methods, Cosmetics -- Methods -- Laws, regulations and rules, Government regulation, Business, Pharmaceuticals and cosmetics industries, Food and beverage industries
Abstract

The Modernization of Cosmetics Regulation Act of 2022 (MoCRA) is poised to revolutionize the U.S. Food and Drug Administration's (FDA's) regulation of the cosmetics industry. A subtitle of the Food [...]

Published
2023

6. English for Specific Purposes. Information Guide 2.

Author

British Council, London (England). English-Teaching Information Centre.

Abstract

This bibliography of materials for teachers of English for specific purposes lists textbooks, technical readers, articles, resource books, reports, dictionaries, reference books, bibliographies, word frequency lists, catalogues of teaching aids, games and activities, current research in Britain, documents available in the archives of the English Teaching Information Centre of the British Council, and theses and dissertations. The textbook section is annotated and covers social sciences, physical sciences, technology (general, engineering, transport, and agriculture), medicine, and commerce (general, commercial correspondence, and hotels and catering). (JB)

Published
1976

7. Curriculum Management for Schools, Colleges, Business.

Author

English, Fenwick W. and English, Fenwick W.

Abstract

What works and does not work in school systems, colleges, and businesses is discussed with a focus on curriculum in the schools and other organizations. Organizational studies were completed in several school systems nationwide. Ten chapters look at the following: (1) curriculum management (the case of the academy, what curriculum is, the nature of school structure and organization, teacher autonomy and authority in schools, some constructs about curriculum in schools); (2) the concept of quality control (curriculum design and delivery, quality control as a concept, curriculum design, curriculum delivery); (3) resolving design and delivery problems (factors in the environment which require quality control, quality control in school settings, delivery problems); (4) curriculum validation (educational conservatism, liberalism, liberationism, and anarchism, procedures for validation, the social utilitarian view, the phenomenological view, the dominant approach, major steps in the process of needs assessment); (5) curriculum alignment (transfer of training as the critical assumption, two types of curriculum alignment, procedures, problems); (6) functional curriculum guides (cycle of basic curriculum design activities, steps in developing functional guides, problems with work design); (7) curriculum mapping (the context, the basic elements, technical difficulties, the dimensions, other descriptive mapping concepts, mapping in the school of the future); (8) curriculum balance (definitions, the importance of outcomes in determining balance, the problem of time, the problem of the co-curriculum, an approach towards determining balance); (9) curriculum auditing (precedents, a model for auditing, standards, format, the power of the audit, common mistakes in undertaking audits); and (10) curriculum evaluation (the framework, evaluation of work design, evaluation of the work performed, work measurement, looking at the total work flow, using results as an indicator of quality work design and work flow). A dialogue with the author follows each chapter; it answers common questions and lists additional activities. Contains approximately 500 references. (SM)

Published
1987

8. Reframing the Conversation: Embracing Workplace Conflict Through a DEIB Lens

Author

Fosten-English, Mary and McNutt, Bryan

Subjects
Mediation -- Reports -- Social aspects, Company business management, Business, Health care industry, Psychology and mental health, Social sciences
Abstract

While the experience of interpersonal conflict at work is not new, managers and EA professionals face increasingly complex and dynamic situations that influence how workplace conflict emerges, how conflict is [...]

Published
2022

9. Sugar Content Claim Litigation on the Rise: Plaintiffs are monitoring whether a company abides by all relevant FDA regulations, so it's important to understand requirements and confirm labeling contains necessary disclaimers

Author

Harrison, Todd, Klesh, Kristen, Onyiuke, Olisa, and English, Melanie

Subjects
United States. Food and Drug Administration -- Laws, regulations and rules, Actions and defenses, Food labeling -- Laws, regulations and rules, Government regulation, Lawsuit/litigation, Business, Pharmaceuticals and cosmetics industries, Food and beverage industries
Abstract

In the last 15 to 20 years, healthy eating and healthy lifestyles have become mainstays in popular culture. People have become more cognizant of what they're putting in their bodies, [...]

Published
2022

10. Optimal use of APPs can enhance a health system's post-COVID-19 financial recovery

Author

Hartsell, Zachary, Ficco, Dane, and English, Laurie

Subjects
Epidemics -- Economic aspects -- United States, Health care industry -- Management, COVID-19 -- Economic aspects, Health care industry, Company business management, Business
Abstract

A Pennsylvania health system's experience shows a focused effort to optimize the use of advanced practice providers (APPs) can yield millions in increased revenue and operating margin opportunities--and can contribute [...]

Published
2020

11. Risk management: A priority for all businesses

Author

English, Kevin J.

Subjects
Strategic planning (Business) -- Methods, Risk management -- Methods, Business insurance -- Usage, Risk management, Business, Business, regional
Abstract

Byline: Special to the RBJ Regardless of the size of your organization, or the industry in which you do business, good and accepted practice requires that there be someone responsible [...]

Published
2022

12. Critiquing FTC's New Health Products Compliance Guidance: The agency is acting like an overbearing parent and undermining its credibility by promulgating stringent regulations via suggestion without input from industry

Author

Harrison, Todd and Venable, Melanie English

Subjects
United States. Federal Trade Commission -- Planning, Dietary supplements industry -- Planning, Government regulation of business, Dietary supplements -- Planning, False advertising, Company business planning, Business, Pharmaceuticals and cosmetics industries, Food and beverage industries
Abstract

Just before the 2022 holiday break, the Federal Trade Commission (FTC) released a new guidance document updating the recommendations for advertising claims about dietary supplement products that the agencv has [...]

Published
2023

13. Servant Leadership: CalCPA Chair Bob Reynolds Poised to Pay It Forward

Author

English, Duden B.M.

Subjects
Accountants, Banking, finance and accounting industries, Business
Abstract

I 'knew' 2019-20 Cali iPA Chair Bob Reynolds before I met him in person. Reynolds was recommended to me years ago by our former California Tax columnist, CalCPA member and [...]

Published
2019

14. Depression complexity prevalence and outcomes among veterans affairs patients in integrated primary care

Author

Lisa V. Rubenstein, Anayansi Lombardero, Alissa Simon, Andrew B. Lanto, Edmund F. Chaney, Ivie English, Katherine J. Hoggatt, Duncan G. Campbell, Barbara Simon, and Thomas J. Waltz

Subjects
Mental Health Services, medicine.medical_specialty, Article, Stress Disorders, Post-Traumatic, Prevalence, medicine, Humans, Bipolar disorder, Psychiatry, Veterans Affairs, Suicidal ideation, Applied Psychology, Depression (differential diagnoses), Veterans, Polypharmacy, Primary Health Care, Depression, business.industry, medicine.disease, Mental health, United States, Alcoholism, United States Department of Veterans Affairs, Psychiatry and Mental health, Mood, medicine.symptom, business, Management of depression
Abstract

Introduction The Veterans Health Administration (VA) Primary Care-Mental Health Integration (PC-MHI) initiative targets depression (MDD), anxiety/posttraumatic stress disorder (PTSD) and alcohol misuse (AM) for care improvement. In primary care, case finding often relies on depression screening. Whereas clinical practice guidelines solely inform management of depression, minimal information exists to guide treatment when psychiatric symptom clusters coexist. We provide descriptive clinical information for care planners about VA PC patients with depression alone, depression plus alcohol misuse, and depression with complex psychiatric comorbidities (PTSD and/or probable bipolar disorder). Method We examined data from a VA study that used a visit-based sampling procedure to screen 10,929 VA PC patients for depression; 761 patients with probable major depression completed baseline measures of health and care engagement. Follow-up assessments were completed at 7 months. Results At baseline, 53% of patients evidenced mental health conditions in addition to depression; 10% had concurrent AM, and 43% had psychiatrically complex depression (either with or without AM). Compared with patients with depression alone or depression with AM, those with psychiatrically complex depression evinced longer standing and more severe mood disturbance, higher likelihood of suicidal ideation, higher unemployment, and higher levels of polypharmacy. Baseline depression complexity predicted worse mental health status and functioning at follow-up. Discussion A substantial proportion of VA primary care patients with depression presented with high medical multimorbidity and elevated safety concerns. Psychiatrically complex depression predicted lower treatment effectiveness, suggesting that PC-MHI interventions should co-ordinate and individualize care for these patients. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Published
2022

15. Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial

Author

Seth Toback, Eva Galiza, Catherine Cosgrove, James Galloway, Anna L Goodman, Pauline A Swift, Sankarasubramanian Rajaram, Alison Graves-Jones, Jonathan Edelman, Fiona Burns, Angela M Minassian, Iksung Cho, Lakshmi Kumar, Joyce S Plested, E Joy Rivers, Andreana Robertson, Filip Dubovsky, Greg Glenn, Paul T Heath, Roy L. Soiza, Robin Brittain-Long, Chiara Scicluna, Carole Edwards, Lynn Mackay, Mariella D'Allesandro, Amy Nicol, Karen Norris, Sandra Mann, Heather Lawrence, Ruth Valentine, Marianne Elizabeth Viljoen, Carol H. Pretswell, Helen Nicholls, Imrozia Munsoor, Agnieszka Meyrick, Christina Kyriakidou, Shalini Iyengar, Arham Jamal, Nick Richards, Helen Price, Bridie Rowbotham, Danielle Bird, Karen Smith, Olga Littler, Kirsty Fielding, Anna Townsend-Rose, Karen Miller, Jessica Davis, Alison Elliot-Garwood, Lauren Trottier, Paul Edwards, Margaret McFarland, Orod Osanlou, Laura Longshaw, Jane Stockport, Lynne Grundy, Katharine Lucy Broad, Karen Regan, Kim Storton, Declan Ryan-Wakeling, Brad Wilson, Malathy Munisamy, John Wright, Anil Shenoy, Beverley English, Lucy Brear, Paola Cicconi, Marta Boffito, Ana Milinkovic, Ruth Byrne, Roya Movahedi, Rosalie Housman, Naveed Kara, Ellen Brown, Andrea Cipriani, Mary-Jane Attenburrow, Katharine A. Smith, Jonathan Packham, Geoff Sparrow, Richard Smith, Josephine M. Rosier, Khalid Saja, Nyasha Nago, Brian Camilleri, Anita Immanuel, Mike Hamblin, Rawlings Osagie, Mahalakshmi Mohan, Hilary Floyd, Suzanne Goddard, Sanjay Mutgi, John Evans, Sean McKeon, Neringa Vilimiene, Rosavic Chicano, Rachel Hayre, Alice Pandaan, Catherine Henshall, Sonia Serrano, Andrea Mazzella, Thurkka Rajeswaran, Moncy Mathew, Karen Bisnauthsing, Laura Bremner, Henry Fok, Franca Morselli, Paola Cinardo, Blair Merrick, Lucy Sowole, Samantha Broadhead, Natalie Palmer, Jessica Cordle, Jaimie Wilson Goldsmith, Enya Cooney, Beth Jackson, Thilina Jayatilleke, Zelda Cheng, Toby Helliwell, Adrian Chudyk, Rafaela Giemza, John Lord Villajin, Noah Yogo, Esther Makanju, Pearl Dulawan, Deepak Nagra, April Buazon, Alice Russell, Georgie Bird, Amardeep Heer, Rex Sarmiento, Balraj Sanghera, Melanie Mullin, Adam Champion, Aisling Bevan, Kinzah Iqbal, Alshia Johnson, Rebecca Clark, Sarah Shaw, Steven Shaw, Amanda Chalk, Martin Lovatt, Caroline Lillicrap, Angela Parker, Jan Hansel, Zhi Wong, Galvin Gan, Eyad Tuma, Jane Minton, Jennifer Murira, Razan Saman, Alistair Hall, Kyra Holliday, Zara Khan, James Calderwood, George Twigg, Helena Baker, Julie Corrigan, Katy Houseman, Subhra Raguvanshi, Dominic Heining, Jake Weddell, Liz Glaves, Kim Thompson, Francis Davies, Ruth Lambley Burke, Emma C. Thomson, Dinesh Saralaya, Lisa Berry, Nancy Hopewell, Leigh Gerdes, Mihaela Pacurar, Saul N. Faust, Jeremy Turner, Christopher Jeanes, Adele Cooper, Jocelyn Keshet-Price, Lou Coke, Melissa Cambell-Kelly, Ketan Dhatariya, Claire Williams, Georgina Marks, James Sudbury, Lisa Rodolico, Judy Bradley, Sharon Carr, Roisin Martin, Angelina Madden, Paul Biagioni, Sonia McKenna, Alison Clinton, Maurice O'Kane, Justin Carter, Matthew Dewhurst, Bill Wetherill, Thandiwe Hoggarth, Katrina Lennon Collins, Marie Chowdhury, Adil Nathoo, Anna Heinen, Orla MacDonald, Claudia Hurducas, Liliana Cifuentes, Harjeevan Gill, Andy Gibson, Raha West, Jane Ewing, Rachel Blacow, John Haughney, Jonathan MacDonald, John Paul Seenan, Stewart Webb, Colin O'Leary, Scott Muir, Beth White, Neil Ritchie, Daniel F. McAuley, Jonathan Stewart, Mariella D'Alessandro, Nicki Lakeman, Laura Purandare, Duncan Browne, David Tucker, Peter Luck, Angharad Everden, Lisa Trembath, Michael Visick, Nick Morley, Laura Reid, Helen Chenoweth, Kirsty Maclean, Ray P. Sheridan, Tom Burden, Craig Francis Lunt, Shirley Todd, Stephanie Estcourt, Jasmine Marie Pearce, Suzanne Wilkins, Cathryn Love-Rouse, Eva Torok-Pollok, Mike Youle, Sara Madge, Danielle Solomon, Aarti Nandani, Janet M. North, Nargis Hemat, Rachel Newport, Philip A. Kalra, Chukwuma Chukwu, Olivia Wickens, Vikki O'Loughlin, Hema Mistry, Louise Harrison, Robert Oliver, Anne-Marie Peers, Jess Zadik, Katie Doyle, David R. Chadwick, Kerry Colling, Caroline Wroe, Marie Branch, Alison Chilvers, Sarah Essex, Mark Stone, Alberto San Francisco Ramos, Emily Beales, Olivia Bird, Zsofia Danos, Hazel Fofie, Cecilia Hultin, Sabina Ikram, Fran Mabesa, Aoife Mescall, Josyanne Pereira, Jennifer Pearce, Natalina Sutton, Emma Snashall, David Neil Baxter, Sara Bennett, Debbie Suggitt, Kerry Hughes, Wiesia Woodyatt, Lynsey Beacon, Alissa Kent, Chris Cooper, Milan Rudic, Simon Tunstall, Matthew Jackson, Claire Hombersley, Patrick Moore, Rebecca Cutts, Andrew Higham, Marwan Bukhari, Mohamed Elnaggar, Michelle Glover, Fiona Richardson, Alexandra Dent, Shahzeb Mirza, Rajiv Ark, Jennie Han, Suzy V. Hope, Philip J. Mitchelmore, Rostam Osanlou, Andrew Freedman, Alison Cooper, Katherine Burton, Kashyap Katechia, Michael Barrett, Jo Salkeld, Natalie Hill, Nathaniel Lee, Jon Perkins, and Polly Fox

Subjects
Adult, Pulmonary and Respiratory Medicine, Trivalent influenza vaccine, medicine.medical_specialty, COVID-19 Vaccines, Adolescent, Influenza vaccine, Population, Placebo, Young Adult, Immunogenicity, Vaccine, Double-Blind Method, Internal medicine, Humans, Medicine, education, Adverse effect, Aged, education.field_of_study, Reactogenicity, SARS-CoV-2, business.industry, COVID-19, Articles, Middle Aged, Vaccine efficacy, Vaccination, Influenza Vaccines, Seasons, business
Abstract

Background The safety and immunogenicity profile of COVID-19 vaccines when administered concomitantly with seasonal influenza vaccines have not yet been reported. We therefore aimed to report the results of a substudy within a phase 3 UK trial, by evaluating the safety, immunogenicity, and efficacy of NVX-CoV2373 when co-administered with licensed seasonal influenza vaccines. Methods We did a planned exploratory substudy as part of the randomised, observer-blinded, placebo-controlled, phase 3 trial of the safety and efficacy of the COVID-19 vaccine (NVX-CoV2373) by co-administrating the influenza vaccine at four study hospitals in the UK. Approximately, the first 400 participants meeting the main study entry criteria—with no contraindications to influenza vaccination—were invited to join the substudy. Participants of the main study were randomly assigned (1:1) to receive two intramuscular injections of either NVX-CoV2373 (5 μg) or placebo (normal saline) 21 days apart; participants enrolled into the substudy were co-vaccinated with a single (0·5 mL) intramuscular, age-appropriate (quadrivalent influenza cell-based vaccine [Flucelvax Quadrivalent; Seqirus UK, Maidenhead] for those aged 18–64 years and adjuvanted trivalent influenza vaccine [Fluad; Seqirus UK, Maidenhead] for those ≥65 years), licensed, influenza vaccine on the opposite deltoid to that of the first study vaccine dose or placebo. The influenza vaccine was administered in an open-label manner and at the same time as the first study injection. Reactogenicity was evaluated via an electronic diary for 7 days after vaccination in addition to monitoring for unsolicited adverse events, medically attended adverse events, and serious adverse events. Immunogenicity was assessed with influenza haemagglutination inhibition and SARS-CoV-2 anti-spike protein IgG assays. Vaccine efficacy against PCR-confirmed, symptomatic COVID-19 was assessed in participants who were seronegative at baseline, received both doses of study vaccine or placebo, had no major protocol deviations affecting the primary endpoint, and had no confirmed cases of symptomatic COVID-19 from the first dose until 6 days after the second dose (per-protocol efficacy population). Immunogenicity was assessed in participants who received scheduled two doses of study vaccine, had a baseline sample and at least one post-vaccination sample, and had no major protocol violations before unmasking (per-protocol immunogenicity population). Reactogenicity was analysed in all participants who received at least one dose of NVX-CoV2373 or placebo and had data collected for reactogenicity events. Safety was analysed in all participants who received at least one dose of NVX-CoV2373 or placebo. Comparisons were made between participants of the substudy and the main study (who were not co-vaccinated for influenza). This study is registered with ClinicalTrials.gov, number NCT04583995. Findings Between Sept 28, 2020, and Nov 28, 2020, a total of 15 187 participants were randomised into the main phase 3 trial, of whom 15 139 received treatment (7569 received dose one of NVX-CoV2373 and 7570 received dose one of placebo). 431 participants were co-vaccinated with a seasonal influenza vaccine in the substudy (217 received NVX-CoV2373 plus the influenza vaccine and 214 received placebo plus the influenza vaccine). In general, the substudy participants were younger, more racially diverse, and had fewer comorbid conditions than those in the main study. Reactogenicity events were more common in the co-administration group than in the NVX-CoV2373 alone group: tenderness (113 [64·9%] of 174 vs 592 [53·3%] of 1111) or pain (69 [39·7%] vs 325 [29·3%]) at injection site, fatigue (48 [27·7%] vs 215 [19·4%]), and muscle pain (49 [28·3%] vs 237 [21·4%]). Incidences of unsolicited adverse events, treatment-related medically attended adverse events, and serious adverse events were low and balanced between the co-administration group and the NVX-CoV2373 alone group. No episodes of anaphylaxis or deaths were reported within the substudy. Co-administration resulted in no change to influenza vaccine immune response although a reduction in antibody responses to the NVX-CoV2373 vaccine was noted. NVX-CoV2373 vaccine efficacy in the substudy (ie, participants aged 18 to

Published
2022

16. Psychothérapie augmentée par rTMS pour les troubles neurologiques fonctionnels

Author

I. English, Hugo Bottemanne, L. Pernet, T. de La Forest Divonne, K. Imadache, Bruno Millet, E. Barron, Sciences, Normes, Démocratie [Paris] (SND), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université - Faculté de médecine [CHU Pitié Salpétrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Psychiatrie Adulte [CHU Pitié-Salpêtière], Environnements et Paléoenvironnements OCéaniques (EPOC), Observatoire aquitain des sciences de l'univers (OASU), Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-École pratique des hautes études (EPHE), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Gynecology, medicine.medical_specialty, business.industry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, [SHS.PSY]Humanities and Social Sciences/Psychology, Neurological disorder, Psychogenic tremor, medicine.disease, 030227 psychiatry, [SHS.HISPHILSO]Humanities and Social Sciences/History, Philosophy and Sociology of Sciences, 03 medical and health sciences, Psychiatry and Mental health, 0302 clinical medicine, Arts and Humanities (miscellaneous), Psychogenic paralysis, medicine, business, ComputingMilieux_MISCELLANEOUS
Abstract

Resume Contexte Nous rapportons l’observation d’une patiente de 47 ans souffrant d’un trouble neurologique fonctionnel (TNF) avec une tetraparesie, des tremblements mixtes et des crises psychogenes non-epileptiques (CPNE), traitee par un protocole de psychotherapie augmentee par stimulation magnetique transcrânienne repetee (rTMS). Intervention Nous avons realise un protocole de psychotherapie biofeedback augmentee par rTMS (vingt seances a raison de deux seances par jour pendant dix jours avec un protocole de stimulation : 1 Hz, 150 % du seuil moteur, sessions de vingt minutes, 300 pulses par sessions) au cours duquel la patiente visualisait l’activite motrice de ses membres superieurs pendant une stimulation de l’aire motrice primaire (AMP). L’evolution de la symptomatologie neurologique a ete evaluee a l’aide de l’echelle MRC pour la force musculaire (Medical Research Council Scale for Muscle Strength). Resultats La symptomatologie a ete amelioree entre les quatrieme et sixieme jours de traitement (huitieme et douzieme seances) avec premierement une levee de la paresie, puis une amelioration secondaire en cascade des autres symptomes fonctionnels. A deux mois, la patiente ne presentait plus de symptome neurologique fonctionnel. Discussion & conclusion Nous proposons plusieurs hypotheses concernant l’efficacite de ce type de protocole de biofeedback utilisant la rTMS. Nous suggerons egalement que ce type de protocole devrait etre systematiquement associe a un accompagnement psychotherapeutique travaillant sur les elements biographiques pour une prise en charge holistique. Cette observation souligne l’interet de potentialiser les psychotherapies cognitivo-comportementales utilisant le principe du conditionnement operant a l’aide de la stimulation cerebrale dans les troubles neurologiques fonctionnels, et motive la realisation d’etudes futures.

Published
2022

17. VTE Prophylaxis in Critically Ill Adults

Author

Karen E. A. Burns, Salmaan Kanji, Yaseen M. Arabi, Damon C. Scales, Mark Crowther, Wei Cheng, Michelle E. Kho, Sangeeta Mehta, Alexandre Tran, Deborah J. Cook, Philip S. Wells, Marc Carrier, Shane W. English, Kwadwo Kyeremanteng, Shannon M. Fernando, Robert A. Fowler, Morten Hylander Møller, Bram Rochwerg, and Behnam Sadeghirad

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, education.field_of_study, business.industry, medicine.drug_class, medicine.medical_treatment, Population, Intermittent pneumatic compression, Low molecular weight heparin, Compression stockings, Critical Care and Intensive Care Medicine, medicine.disease, Pulmonary embolism, law.invention, Randomized controlled trial, law, Heparin-induced thrombocytopenia, Meta-analysis, medicine, cardiovascular diseases, Cardiology and Cardiovascular Medicine, Intensive care medicine, education, business
Abstract

Background Critically ill adults are at increased risk of VTE, including DVT, and pulmonary embolism. Various agents exist for venous thromboprophylaxis in this population. Research Question What is the comparative efficacy and safety of prophylaxis agents for prevention of VTE in critically ill adults? Study Design and Methods Systematic review and network meta-analysis of randomized clinical trials (RCTs) evaluating efficacy of thromboprophylaxis agents among critically ill patients. We searched six databases (including PubMed, EMBASE, and Medline) from inception through January 2021 for RCTs of patients in the ICU receiving pharmacologic, mechanical, or combination therapy (pharmacologic agents and mechanical devices) for thromboprophylaxis. Two reviewers performed screening, full-text review, and extraction. We used the Grading of Recommendations Assessment, Development, and Evaluation to rate certainty of effect estimates. Results We included 13 RCTs (9,619 patients). Compared with control treatment (a composite of no prophylaxis, placebo, or compression stockings only), low-molecular-weight heparin (LMWH) reduced the incidence of DVT (OR, 0.59 [95% credible interval [CrI], 0.33-0.90]; high certainty) and unfractionated heparin (UFH) may reduce the incidence of DVT (OR, 0.82 [95% CrI, 0.47-1.37]; low certainty). LMWH probably reduces DVT compared with UFH (OR, 0.72 [95% CrI, 0.46-0.98]; moderate certainty). Compressive devices may reduce risk of DVT compared with control treatments; however, this is based on low-certainty evidence (OR, 0.85 [95% CrI, 0.50-1.50]). Combination therapy showed unclear effect on DVT compared with either therapy alone (very low certainty). Interpretation Among critically ill adults, compared with control treatment, LMWH reduces incidence of DVT, whereas UFH and mechanical compressive devices may reduce the risk of DVT. LMWH is probably more effective than UFH in reducing incidence of DVT and should be considered the primary pharmacologic agent for thromboprophylaxis. The efficacy and safety of combination pharmacologic therapy and mechanical compressive devices were unclear. Trial Registry Open Science Framework; URL: https://osf.io/694aj

Published
2022

18. Pregnancies in women with Turner syndrome: a retrospective multicentre UK study

Author

Lucy MacKiliop, Catriona Bhagra, Lowri A. Allen, Aisling Carroll, Katherine von Klemperer, Fionnuala M. McAuliffe, R. Katie Morris, Paul Timmons, Catherine Head, Asha Shetty, Farah Siddiqui, Aidan P Bolger, D. Aled Rees, Matilde Calanchini, Claire Alexander, Philip J. Steer, Samantha Bonner, Linden Stocker, Rachael James, Dawn Adamson, Lydia Simpson, Eleanor Joy, Lucy Hudsmith, Niamh Keating, Sarah Vause, Mandeep K. Kaler, Helen E Turner, Ruth T Casey, Kate English, Aarthi R Mohan, Stephanie L. Curtis, and Matthew Cauldwell

Subjects
Aortic dissection, medicine.medical_specialty, education.field_of_study, Pregnancy, Referral, business.industry, Obstetrics, Population, Obstetrics and Gynecology, medicine.disease, Spontaneous pregnancy, Egg donation, Turner syndrome, Medicine, business, education, Cohort study
Abstract

Objective\ud To determine the characteristics and outcomes of pregnancy in women with Turner Syndrome\ud \ud Design\ud Retrospective 20-year cohort study (2000-2020)\ud \ud Setting\ud 16 tertiary referral maternity units in the UK\ud \ud Population or Sample\ud 81 women with Turner syndrome who became pregnant\ud \ud Methods\ud Retrospective chart analysis\ud \ud Main Outcome Measures\ud Mode of conception, pregnancy outcomes\ud \ud Results\ud We obtained data on 127 pregnancies in 81 women with a Turner phenotype. All non-spontaneous pregnancies (54/127 (42.5%)) were by egg donation. Only 9/31 (29%) of pregnancies in women with karyotype 45,X were spontaneous, compared with 53/66 (80.3%) with mosaic karyotype 45,X/46,XX (p

Published
2022

19. Tracing, mixing, and innocent claimants

Author

Jordan English and Mohammud Jaamae Hafeez-Baig

Subjects
Bank account, Presumption of innocence, Business, Tracing, Law, Mixing (physics), Law and economics
Abstract

Faced with the problem that arises where multiple innocent claimants have contributed to a mixed fund that is now insufficient to meet all of their claims, English and Australian courts have suggested three solutions: (i) the rule in Clayton's Case; (ii) the ‘simple pari passu’ approach; and (iii) the ‘rolling charge’ or ‘North American’ approach. In Caron v Jahani (No 2) the New South Wales Court of Appeal adopted a simplified version of the third solution: the ‘simplified rolling charge’ approach. In doing so, the Court demonstrated that once the rule in Clayton's Case is (rightly) discarded, what remains is not simply a binary choice between the second and third solutions. We argue that English courts should revisit their approach to the problem posed at the outset by jettisoning the rule in Clayton's Case and by adopting the simplified rolling charge approach.

Published
2023

20. Smoking Methylation Marks for Prediction of Urothelial Cancer Risk

Author

Damien M Bolton, Theodore M. Brasky, Maree Brinkman, Melissa C. Southey, Julie K. Bassett, Roger L. Milne, Ee Ming Wong, Jihoon E. Joo, Parveen Bhatti, Aladdin H. Shadyab, Chenglong Yu, Dallas R. English, Pierre Antoine Dugué, Kristina M. Jordahl, Graham G. Giles, John L. Hopper, Enes Makalic, Lesley Tinker, Daniel F. Schmidt, and Anthony Longano

Subjects
Oncology, medicine.medical_specialty, education.field_of_study, Epidemiology, business.industry, Population, Confounding, Area under the curve, Odds ratio, Methylation, Internal medicine, Cohort, DNA methylation, medicine, education, business, Cohort study
Abstract

Background: Self-reported information may not accurately capture smoking exposure. We aimed to evaluate whether smoking-associated DNA methylation markers improve urothelial cell carcinoma (UCC) risk prediction. Methods: Conditional logistic regression was used to assess associations between blood-based methylation and UCC risk using two matched case–control samples: 404 pairs from the Melbourne Collaborative Cohort Study (MCCS) and 440 pairs from the Women's Health Initiative (WHI) cohort. Results were pooled using fixed-effects meta-analysis. We developed methylation-based predictors of UCC and evaluated their prediction accuracy on two replication data sets using the area under the curve (AUC). Results: The meta-analysis identified associations (P < 4.7 × 10−5) for 29 of 1,061 smoking-associated methylation sites, but these were substantially attenuated after adjustment for self-reported smoking. Nominally significant associations (P < 0.05) were found for 387 (36%) and 86 (8%) of smoking-associated markers without/with adjustment for self-reported smoking, respectively, with same direction of association as with smoking for 387 (100%) and 79 (92%) markers. A Lasso-based predictor was associated with UCC risk in one replication data set in MCCS [N = 134; odds ratio per SD (OR) = 1.37; 95% CI, 1.00–1.90] after confounder adjustment; AUC = 0.66, compared with AUC = 0.64 without methylation information. Limited evidence of replication was found in the second testing data set in WHI (N = 440; OR = 1.09; 95% CI, 0.91–1.30). Conclusions: Combination of smoking-associated methylation marks may provide some improvement to UCC risk prediction. Our findings need further evaluation using larger data sets. Impact: DNA methylation may be associated with UCC risk beyond traditional smoking assessment and could contribute to some improvements in stratification of UCC risk in the general population.

Published
2021

21. Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada

Author

Alain Tremblay, Christian Couture, John R. Goffin, Paul MacEachern, Zhaolin Xu, Annette McWilliams, Dean A. Regier, Garth Nicholas, Kayvan Amjadi, Frances A. Shepherd, William K. Evans, Paul Burrowes, Ian Cromwell, Jean M. Seely, Glenwood D. Goss, Michael R. Johnston, Rick Bhatia, John Yee, Martin C. Tammemägi, Richard J. Finley, Serge Puksa, Heidi C. Roberts, Ming-Sound Tsao, John R. Mayo, Sonya Cressman, Stephen Lam, Simon Martel, Natasha B. Leighl, Corneliu Bolbocean, Kazuhiro Yasufuku, Stefan J. Urbanski, S. Atkar-Khattra, Harmanjatinder S. Sekhon, Diana N. Ionescu, Stuart Peacock, Daria Manos, Geoffrey Liu, Wan C. Tan, Don D. Sin, Kamyar Soghrati, John C. English, David M. Hwang, Jean-Claude Cutz, and Team, Pan-Canadian Early Detection of Lung Cancer

Subjects
Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Canada, Lung Neoplasms, Cost effectiveness, Cost-Benefit Analysis, Population, Treatment of lung cancer, Lung cancer screening, medicine, Cost analysis, Humans, Mass Screening, Lung cancer, education, Mass screening, Average cost, Early Detection of Cancer, Randomized Controlled Trials as Topic, education.field_of_study, business.industry, Cancer, Original Articles, Middle Aged, medicine.disease, Surgery, Oncology, Emergency medicine, Screening, Female, Cost-effectiveness, business, Tomography, X-Ray Computed
Abstract

Background It is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening programs. The decision to implement such programs should be informed by data on resource utilization and costs. Methods Resource utilization data were collected prospectively from 2059 participants in the Pan-Canadian Early Detection of Lung Cancer Study using low-dose computed tomography (LDCT). Participants who had 2% or greater lung cancer risk over 3 years using a risk prediction tool were recruited from seven major cities across Canada. A cost analysis was conducted from the Canadian public payer's perspective for resources that were used for the screening and treatment of lung cancer in the initial years of the study. Results The average per-person cost for screening individuals with LDCT was USD453 (95% confidence interval [CI], USD400–USD505) for the initial 18-months of screening following a baseline scan. The screening costs were highly dependent on the detected lung nodule size, presence of cancer, screening intervention, and the screening center. The mean per-person cost of treating lung cancer with curative surgery was USD33,344 (95% CI, USD31,553–USD34,935) over 2 years. This was lower than the cost of treating advanced-stage lung cancer with chemotherapy, radiotherapy, or supportive care alone, (USD47,792; 95% CI, USD43,254–USD52,200; p = 0.061). Conclusion In the Pan-Canadian study, the average cost to screen individuals with a high risk for developing lung cancer using LDCT and the average initial cost of curative intent treatment were lower than the average per-person cost of treating advanced stage lung cancer which infrequently results in a cure.

Published
2022

22. Prospective Evaluation over 15 Years of Six Breast Cancer Risk Models

Author

Roger L. Milne, Andy C. H. Lee, Melissa C. Southey, Robert J. MacInnis, Tu Nguyen-Dumont, Graham G. Giles, Ingrid Winship, John L. Hopper, Mary Beth Terry, Sherly X. Li, Dallas R. English, Antonis C. Antoniou, Li, Sherly X [0000-0002-7840-4051], Nguyen-Dumont, Tú [0000-0002-6217-0182], English, Dallas R [0000-0001-7828-8188], Antoniou, Antonis C [0000-0001-9223-3116], MacInnis, Robert J [0000-0002-1627-5047], Apollo - University of Cambridge Repository, Antoniou, Antonis [0000-0001-9223-3116], Lee, Andrew [0000-0003-0677-0252], Li, Sherly X. [0000-0002-7840-4051], English, Dallas R. [0000-0001-7828-8188], Antoniou, Antonis C. [0000-0001-9223-3116], and MacInnis, Robert J. [0000-0002-1627-5047]

Subjects
Ibis, Cancer Research, biology, business.industry, Cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, biology.organism_classification, medicine.disease, calibration, Prospective evaluation, Confidence interval, Article, Clinical research, Breast cancer, breast cancer, Oncology, risk model, Medicine, Family history, business, RC254-282, Demography, Cohort study, discrimination
Abstract

Prospective validation of risk models is needed to assess their clinical utility, particularly over the longer term. We evaluated the performance of six commonly used breast cancer risk models (IBIS, BOADICEA, BRCAPRO, BRCAPRO-BCRAT, BCRAT, and iCARE-lit). 15-year risk scores were estimated using lifestyle factors and family history measures from 7608 women in the Melbourne Collaborative Cohort Study who were aged 50-65 years and unaffected at commencement of follow-up two (conducted in 2003-2007), of whom 351 subsequently developed breast cancer. Risk discrimination was assessed using the C-statistic and calibration using the expected/observed number of incident cases across the spectrum of risk by age group (50-54, 55-59, 60-65 years) and family history of breast cancer. C-statistics were higher for BOADICEA (0.59, 95% confidence interval (CI) 0.56-0.62) and IBIS (0.57, 95% CI 0.54-0.61) than the other models (p-difference ��� 0.04). No model except BOADICEA calibrated well across the spectrum of 15-year risk (p-value < 0.03). The performance of BOADICEA and IBIS was similar across age groups and for women with or without a family history. For middle-aged Australian women, BOADICEA and IBIS had the highest discriminatory accuracy of the six risk models, but apart from BOADICEA, no model was well-calibrated across the risk spectrum., This work was primarily supported by grant 1129136 from the Australian National Health and Medical Research Council (NHMRC) (https://www.nhmrc.gov.au/). MCCS cohort recruitment was funded by Cancer Council Victoria (https://www.cancervic.org.au/) and VicHealth (https://www.vichealth.vic.gov.au/). The MCCS was further supported by Australian NHMRC grants 209057, 396414 and 1074383, and ongoing follow-up and data management has been funded by Cancer Council Victoria since 1995. Cases and their vital status were ascertained through the Victorian Cancer Registry and the Australian Institute of Health and Welfare, including the National Death Index and the Australian Cancer Database.TN-D is a recipient of a Career Development Fellowship from the National Breast Cancer Foundation (Australia). JLH and MCS are Senior Principal and Senior Research Fellows of the National Health and Medical Research Council (Australia), respectively. ACA and AJL are supported by grants from Cancer Research UK (C12292/A20861 and PPRPGM19 Nov20\100002).

Published
2021

23. Cheers to the New Chair! Mix Values With Guiding Principles, and Bob's Your Uncle, Success!

Author

English, Damien B.M.

Subjects
Association executives -- Interviews, Football, Banking, finance and accounting industries, Business, California Society of Certified Public Accountants -- Officials and employees
Abstract

It's not hard to feel at ease with CalCPA Chair Lewis Sharpstone. Hearing the familiar (at least to me) British accent immediately disarmed me, and connecting over our shared knowledge [...]

Published
2018

24. Effect of direct-fed microbial on Enterococci antibiotic resistance: Studying the antibiotic resistance of Enterococcus sp. in cattle feces as impacted by dietary supplementation with Lactobacillus salivarius L28

Author

English, Andrea R., Echeverry, Alejandro, Sarturi, Jhones O., Opheim, Tosha L., Nightingale, Kendra K., Miller, Mark F., and Brashears, Mindy M.

Subjects
Animal husbandry, Cattle, Cattle industry, Microbial drug resistance, Feedlots, Dietary supplements, Business, Food and beverage industries
Abstract

This study was designed to determine the antibiotic resistance patterns of Enterococcus sp. isolated from feedlot cattle supplemented with a novel direct-fed microbial (DFM) Lactobacillus salivarius (L28) in replacement of [...]

Published
2018

25. Business Intelligence as a Source of Competitive Advantage in SMEs: A Systematic Review

Author

Vincent English and Markus Hoffmann

Subjects
business intelligence, competitive advantage, sme, capabilities, key performance, Business, HF5001-6182
Abstract

Competitive advantage is the ‘Holy Grail’ in strategic management theory. What makes a company more successful than its rivals has dominated scholarship in this area for more than 20 years. There have been two main theories proposed to attempt to identify the important resources and capabilities that configure to build competitive advantage; the Resource-based View and Dynamic Capability View. There is a growing literature stream in the area of Business Intelligence (BI) and Big Data Analytics with regard to both the computer technology and business management constructs. However, the literature is silent of the affordances of BI for Small to Medium Enterprises (SMEs), and so a significant gap in the literature remains. This discussion aims to signal the need to fill that gap and to build awareness of BI as a potentially significant contributor to sustained competitive advantage in SMEs underpinned by the iniquitousness of cloud applications previously the domain of Multinational Corporations.

Published
2018
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26. Alcohol and tobacco use and risk of multiple myeloma: A case‐control study

Author

Roger L. Milne, Robert J. MacInnis, Nicole Wong Doo, H. Miles Prince, Marina T. Leeuwen, Douglas E. Joshua, Wendy Cozen, Graham G. Giles, Harindra Jayasekara, Julie K. Bassett, Claire M. Vajdic, Simon J. Harrison, Dallas R. English, John L. Hopper, Fiona J. Bruinsma, and Simon Cheah

Subjects
Oncology, chemistry.chemical_compound, medicine.medical_specialty, Tobacco use, chemistry, business.industry, Internal medicine, medicine, Case-control study, Alcohol, business, medicine.disease, Multiple myeloma
Abstract

Multiple myeloma (MM) is the second most common hematological cancer and causes significant mortality and morbidity. Knowledge regarding modifiable risk factors for MM remains limited. This analysis of an Australian population-based case-control family study investigates whether smoking or alcohol consumption is associated with risk of MM and related diseases. Incident cases (

Published
2021

27. Sonographic Screening of Distance Runners for the Development of Future Achilles and Patellar Tendon Pain

Author

Sarah Eby, Joy English, Ziva Petrin, Daniel M Cushman, Keith Cummings, and Masaru Teramoto

Subjects
Male, musculoskeletal diseases, medicine.medical_specialty, Physical Therapy, Sports Therapy and Rehabilitation, Achilles Tendon, Asymptomatic, Salt lake, Musculoskeletal Pain, Patellar Ligament, Humans, Medicine, Orthopedics and Sports Medicine, Prospective Studies, Prospective cohort study, Ultrasonography, Achilles tendon, business.industry, Hazard ratio, Ultrasound, musculoskeletal system, Patellar tendon, Surgery, medicine.anatomical_structure, Tendinopathy, Tendon abnormalities, Female, medicine.symptom, business, human activities
Abstract

Objective The 2 primary aims of this study were to identify ultrasonographic tendon abnormalities in asymptomatic runners and to examine the likelihood of developing pain in runners with ultrasound abnormalities compared with those without abnormalities. Design Longitudinal, prospective cohort study. Setting 2019 Salt Lake City Marathon. Participants Recreational half-marathon and full-marathon runners. Assessment of risk factors The Achilles and patellar tendons of asymptomatic runners were examined with ultrasound imaging before a running event. Runners were monitored for self-reported outcomes of pain in the examined tendons at 1, 3, 6, and 12 months after the event. Main outcome measures Development of pain based on the presence of asymptomatic tendon abnormalities. Results One hundred thirty-eight runners (36.2 ± 12.0 years, 49.3% men, and 31.2% full-marathon runners) were included. Ultrasound abnormalities of the Achilles and patellar tendons were identified in 24.6% and 39.1% of the runners before the race, respectively. Ultrasound abnormalities were significantly associated with approximately a 3-fold increase [hazard ratio (HR) = 2.55, P = 0.004] in the hazard of developing pain in the Achilles tendon and patellar tendon (HR = 1.67, P = 0.042) over the year after the race. Positive and negative predictive values of developing pain over the year were 34.1% and 87.2%, respectively, for abnormal findings in the Achilles tendon, and 22.9% and 85.0%, respectively, for the patellar tendon. Conclusions The presence of ultrasonographic abnormalities is associated with increased development of pain in the Achilles and patellar tendons within 1 year of a marathon or half marathon.

Published
2021

28. National Surveillance for Acute Flaccid Myelitis — United States, 2018–2020

Author

Brian Emery, Randall English, Halle Getachew, Eileen Yee, Adriana S. Lopez, Shannon Rogers, Sarah E. Kidd, and Janell Routh

Subjects
Male, medicine.medical_specialty, Weakness, Pediatrics, Health (social science), Adolescent, Epidemiology, Health, Toxicology and Mutagenesis, Upper limb involvement, Health Information Management, medicine, Paralysis, Humans, Full Report, Pleocytosis, Child, business.industry, technology, industry, and agriculture, General Medicine, Neuromuscular Diseases, Myelitis, Acute flaccid myelitis, United States, Child, Preschool, Population Surveillance, Etiology, Central Nervous System Viral Diseases, Female, medicine.symptom, Complication, business
Abstract

Acute flaccid myelitis (AFM), a recognized complication of certain viral infections, is a serious neurologic condition that predominantly affects previously healthy children and can progress rapidly, leading to respiratory insufficiency and permanent paralysis. After national AFM surveillance began in 2014, peaks in AFM cases were observed in the United States in 2014, 2016, and 2018 (1). On the basis of this biennial pattern, an increase in AFM was anticipated in 2020. To describe the epidemiology of confirmed AFM cases since 2018, demographic, clinical, and laboratory information collected as part of national AFM surveillance was reviewed. In 2018, a total of 238 confirmed AFM cases were reported to CDC, compared with 47 cases in 2019 and 32 in 2020. Enterovirus D68 (EV-D68) was detected in specimens from 37 cases reported in 2018, one case in 2019 and none in 2020. Compared with 2018, cases reported during 2019-2020 occurred in older children and were less frequently associated with upper limb involvement, febrile or respiratory prodromal illness, or cerebrospinal fluid (CSF) pleocytosis. These findings suggest that the etiologies of AFM in 2019 and 2020 differed from those in 2018. The absence of an increase in cases in 2020 reflects a deviation from the previously observed biennial pattern, and it is unclear when the next increase in AFM should be expected. Clinicians should continue to maintain vigilance and suspect AFM in any child with acute flaccid limb weakness, particularly in the setting of recent febrile or respiratory illness.

Published
2021

29. Optic Nerve Germinoma and Transient Spontaneous Regression—More Than Meets the Eye

Author

Sally L. Painter, Richard Gagen, William B. Lo, Claire Geurten, Bryony Carr, Kim Neuling, Claire Bowen, Heather Stirling, Jerald Williams, Miriam Pavon-Mengual, and Martin English

Subjects
medicine.medical_specialty, Germinoma, business.industry, Hematology, medicine.disease, Lesion, Oncology, Glioma, Pediatrics, Perinatology and Child Health, Intracranial Germinoma, medicine, Optic nerve, Germ cell tumors, Radiology, medicine.symptom, business, Confusion
Abstract

Infiltration of the optic pathway by germ cell tumors is exceptional and can lead to confusion with glioma or inflammatory conditions. We present the case of a 14-year-old girl with an optic nerve germinoma extending to the hypothalamus and manifesting as panhypopituitarism and visual loss. The patient experienced spontaneous regression of the lesion followed by secondary deterioration requiring treatment. Four other cases of spontaneously regressing intracranial germinoma followed by regrowth have been reported in the literature. This report highlights the importance of clinical and radiologic monitoring of intracranial germinoma, even in the event of initial spontaneous improvement.

Published
2021

30. Intravenous alteplase has different effects on the efficacy of aspiration and stent retriever thrombectomy: analysis of the COMPASS trial

Author

Michael Kelly, Imran Chaudry, J Mocco, Johanna T Fifi, David Fiorella, Joey English, Ansaar T Rai, Keith Woodward, Adnan H. Siddiqui, Muhammad Waqas, Kenneth V. Snyder, Adam S Arthur, Italo Linfante, Elad I. Levy, Maxim Mokin, Aquilla S Turk, Donald Frei, Reade De Leacy, Ricardo A. Hanel, Kyle M Fargen, Josser E Delgado Almandoz, and Blaise Baxter

Subjects
medicine.medical_specialty, medicine.medical_treatment, Brain Ischemia, Modified Rankin Scale, Post-hoc analysis, Humans, Medicine, Stroke, Retrospective Studies, Thrombectomy, Stent retriever, Univariate analysis, business.industry, Cerebral infarction, Infant, Newborn, Infant, Stent, Cerebral Infarction, General Medicine, Thrombolysis, medicine.disease, Surgery, Treatment Outcome, Tissue Plasminogen Activator, Stents, Neurology (clinical), business
Abstract

BackgroundThere is conflicting evidence on the utility of intravenous (IV) alteplase in patients with emergent large vessel occlusion (ELVO) treated with mechanical thrombectomy (MT).MethodsThis was a post hoc analysis of the COMPASS: a trial of aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion. We compared clinical, procedural and angiographic outcomes of patients with and without prior IV alteplase administration.ResultsIn the COMPASS trial, 235 patients had presented to the hospital within the first 4 hours of stroke symptom onset and were eligible for analysis. On univariate analysis, administration of IV alteplase prior to MT was found to be significantly associated with favorable outcomes (modified Rankin scale (mRS) 0–2 at 3 months; 55.6% vs 40.0% in the MT-only group, P=0.037). However, on multivariate analysis, only baseline (pre-stroke) mRS, admission National Institutes of Health Stroke Scale (NIHSS) score and age were identified as independent predictors of favorable outcomes at 3 months. We found higher final thrombolysis in cerebral infarction (TICI) 2b/3 rates in patients without the use of alteplase prior to the aspiration first approach (100.0% vs 87.9% in IV altepase +aspiration first MT, P=0.03). In the stent retriever first group, final TICI 2b/3 rates were identical in patients with and without IV alteplase administration (87.5% and 87.5%, P=1.0).ConclusionsPrior administration of IV alteplase may adversely affect the efficacy of aspiration, but does not seem to influence the stent retriever first approach to MT in patients with anterior circulation ELVO.

Published
2021

31. A homozygous <scp> GRIN1 </scp> null variant causes a more severe phenotype of early infantile epileptic encephalopathy

Author

Joel English, Alexander J M Blakes, Siddharth Banka, and Helen Basu

Subjects
N-Methylaspartate, GRIN1, media_common.quotation_subject, Nonsense, Nerve Tissue Proteins, Receptors, N-Methyl-D-Aspartate, splicing, Epilepsy, Neurodevelopmental disorder, Genetics, Humans, Medicine, Missense mutation, Global developmental delay, developmental disorder, Genetics (clinical), media_common, biology, business.industry, Infant, medicine.disease, Phenotype, Developmental disorder, biology.protein, epilepsy, business, Spasms, Infantile, null variant
Abstract

Pathogenic variants in glutamate receptor, ionotropic, NMDA-1 (GRIN1) cause an autosomal dominant or recessive neurodevelopmental disorder with global developmental delay, with or without seizures (AD or AR GRIN1-NDD). Here, we describe a novel homozygous canonical splice site variant in GRIN1 in a 12-month-old boy with early infantile epileptic encephalopathy and severe global developmental delay. This represents only the second family with a homozygous predicted-null variant in GRIN1 reported to date. We review the published literature on AR GRIN1-NDD and find that the phenotype in our patient is much more severe than those seen with homozygous missense variants. A similarly severe phenotype of intractable epilepsy and infantile death has only been reported in one other family with a homozygous nonsense variant in GRIN1. We, therefore, propose that biallelic predicted-null variants in GRIN1 can cause a markedly more severe clinical phenotype than AR GRIN1-NDD caused by missense variants.

Published
2021

32. Inflammation-Related Marker Profiling of Dietary Patterns and All-cause Mortality in the Melbourne Collaborative Cohort Study

Author

James R. Hébert, Arve Ulvik, Nitin Shivappa, Per Magne Ueland, Anne Sophie Navionis, Allison M. Hodge, Pierre Antoine Dugué, Melissa C. Southey, Graham G. Giles, Øivind Midttun, Harindra Jayasekara, Julie K. Bassett, Leon Flicker, Robert J. MacInnis, Roger L. Milne, Gianluca Severi, Klaus Meyer, Dallas R. English, Paolo Vineis, Sabina Rinaldi, and Sherly X. Li

Subjects
0301 basic medicine, medicine.medical_specialty, Medicine (miscellaneous), Inflammation, Healthy eating, Cohort Studies, 03 medical and health sciences, Internal medicine, Linear regression, medicine, Humans, Aged, Aged, 80 and over, 030109 nutrition & dietetics, Nutrition and Dietetics, Proportional hazards model, Nutritional epidemiology, business.industry, Middle Aged, Diet, Cross-Sectional Studies, 030104 developmental biology, Biomarker (medicine), Diet, Healthy, medicine.symptom, business, All cause mortality, Cohort study
Abstract

Nutritional epidemiology research using self-reported dietary intake is prone to measurement error. Objective methods are being explored to overcome this limitation.We aimed to examine 1) the association between plasma markers related to inflammation and derive marker scores for dietary patterns [Mediterranean dietary score (MDS), energy-adjusted Dietary Inflammatory Index (E-DIITM), Alternative Healthy Eating Index 2010 (AHEI)] and 2) the associations of these marker scores with mortality.Weighted marker scores were derived from the cross-sectional association between 30 plasma markers and each dietary score (assessed using food-frequency questionnaires) using linear regression for 770 participants in the Melbourne Collaborative Cohort Study (aged 50-82 y). Prospective associations between marker scores and mortality (n = 249 deaths) were assessed using Cox regression (median follow-up: 14.4 y).The MDS, E-DII, and AHEI were associated (P 0.05) with 9, 14, and 11 plasma markers, respectively. Healthier diets (higher MDS and AHEI, and lower anti-inflammatory, E-DII) were associated with lower concentrations of kynurenines, neopterin, IFN-γ, cytokines, and C-reactive protein. Five of 6 markers common to the 3 dietary scores were components of the kynurenine pathway. The 3 dietary-based marker scores were highly correlated (Spearman ρ: -0.74, -0.82, and 0.93). Inverse associations (for 1-SD increment) were observed with all-cause mortality for the MDS marker score (HR: 0.84; 95% CI: 0.72-0.98) and the AHEI marker score (HR: 0.76; 95% CI: 0.66-0.89), whereas a positive association was observed with the E-DII marker score (HR: 1.18; 95% CI: 1.01-1.39). The same magnitude of effect was not observed for the respective dietary patterns.Markers involved in inflammation-related processes are associated with dietary quality, including a substantial overlap between markers associated with the MDS, the E-DII, and the AHEI, especially kynurenines. Unfavorable marker scores, reflecting poorer-quality diets, were associated with increased mortality.

Published
2021

33. Estimated Economic Impacts of the 2019 Midwest Floods

Author

R. Jamey Menard, Burton C. English, David W. Hughes, Michael Gunderson, and S. Aaron Smith

Subjects
Crop, Agriculture, business.industry, Natural hazard, Sowing, Climate change, Revenue, Business, Economic impact analysis, Agricultural economics, Crop protection
Abstract

In the spring of 2019, U.S. agriculture experienced a record high number of prevented planted acres primarily due to historic rainfall across large portions of the Corn Belt and Mid-South. Producers of corn, upland cotton, soybean, and wheat were impacted with a substantial loss of revenue due to no crops being produced and marketed. With about 11.4 million acres of corn not planted, foregone gross revenue from crop sales likely exceeded $6 billion alone. Instead of focusing on the loss of producers’ incomes as a result of prevented planted acres, our analysis focuses on the economic impacts, due to lost sales, for firms that provide inputs to farmers. Acres prevented from planting resulted in producers not incurring typical expenditures for planting and post planting inputs such as seed, crop nutrients, and crop protection (herbicides, insecticides, fungicides, etc.). Agricultural input manufacturers, wholesalers, and retailers do not have similar opportunities to insure against foregone sales and have received no disaster assistance payments. Normally, the large geographic footprint of many of these firms mitigates the impact of localized weather effects. However, given the widespread nature of the wet spring, these firms were negatively affected across Corn Belt and Mid-South representing a substantial production area. Regional economic impact of declines in sales by agricultural input providers due to wet weather-based prevented plantings on 13.1 million acres. Direct sale losses of $2.9 billion led to $4.5 billion losses in total sales that were concentrated in parts of Minnesota, South Dakota, and Illinois.

Published
2021

34. Prospective, Multicenter, Controlled Trial of Mobile Stroke Units

Author

Chethan P. Venkatasubba Rao, Kenny Phan, Bryan M Villareal, Jenny Im, Saad Mir, Noopur Singh, Brandi Schimpf, James McCarthy, Nichole Bosson, May Nour, Carla P Sherman, Josh Z Willey, James C. Grotta, Greg Gilbert, Kim Ackerson, Jason Mackey, Edgar Lechuga, Anne W Alexandrov, Suja S Rajan, Laura Griffin, David Persse, Jonathan Stephenson, James P Rhudy, William J. Jones, Nicole R Gonzales, Vivek Misra, David Ornelas, Nicole Rangel-Gutierrez, Joseph S. Kass, Michael O. Gonzalez, Joey English, David Chiu, Michael Eisshofer, Janice Miller, Ritvij Bowry, Matthew E Fink, Jay Volpi, Mackenzie P. Lerario, Yvette Sanders, Kelly Silnes, Asha P Jacob, Marianne Gausche-Hill, Stephanie A. Parker, Mengxi Wang, Sarah Collins, Kevin M. Brown, Jeffrey L Saver, Jose-Miguel Yamal, Babak B. Navi, Tom Flanagan, Andrei V. Alexandrov, Patti Bratina, Ilana Spokoyny, Elizabeth A Noser, and Nobl Barazangi

Subjects
medicine.medical_specialty, business.industry, MEDLINE, General Medicine, Odds ratio, Tissue plasminogen activator, law.invention, Randomized controlled trial, law, Severity of illness, medicine, Emergency medical services, Observational study, Radiology, Tomography, business, medicine.drug
Abstract

Background Mobile stroke units (MSUs) are ambulances with staff and a computed tomographic scanner that may enable faster treatment with tissue plasminogen activator (t-PA) than standard m...

Published
2021

35. Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

Author

Akowuah, Enoch, Benson, Ruth A., Caruana, Edward J., Chetty, Govind, Edwards, John, Forlani, Stefano, Gradinariu, George, Murphy, Gavin J., Oo, Aung Ye, Patel, Akshay J., Ridley, Brenda, Rogers, Luke J., Sanders, Julie, Tyson, Nathan, Vaja, Ricky, Siaw-Acheampong, Kwabena, Argus, Leah, Chaudhry, Daoud, Dawson, Brett E., Glasbey, James C., Gujjuri, Rohan R., Jones, Conor S., Kamarajah, Sivesh K., Khatri, Chetan, Keatley, James M., Lawday, Samuel, Li, Elizabeth, Mann, Harvinder, Marson, Ella J., Mclean, Kenneth A., Picciochi, Maria, Taylor, Elliott H., Tiwari, Abhinav, Simoes, Joana FF., Trout, Isobel M., Venn, Mary L., Wilkin, Richard JW., Bhangu, Aneel, Nepogodiev, Dmitri, Dajti, Irida, Gjata, Arben, Boccalatte, Luis, Modolo, Maria Marta, Cox, Daniel, Pockney, Peter, Townend, Philip, Aigner, Felix, Kronberger, Irmgard, Hossain, Kamral, VanRamshorst, Gabrielle, Lawani, Ismail, Ataide, Gustavo, Baiocchi, Glauco, Buarque, Igor, Gohar, Muhammad, Slavchev, Mihail, Agarwal, Arnav, Brar, Amanpreet, Martin, Janet, Olivos, Maricarmen, Calvache, Jose, Perez Rivera, Carlos Jose, Hadzibegovic, Ana Danic, Kopjar, Tomislav, Mihanovic, Jakov, Klat, Jaroslav, Novysedlak, René, Christensen, Peter, El-Hussuna, Alaa, Batista, Sylvia, Lincango, Eddy, Emile, Sameh H., Mengesha, Mengistu Gebreyohanes, Hailu, Dr. Samuel, Tamiru, Hailu, Kauppila, Joonas, Laukkarinen, Johanna, Arnaud, Alexis, Albertsmeiers, Markus, Lederhuber, Hans, Loffler, Markus, Tabiri, Stephen, Metallidis, Symeon, Tsoulfas, Georgios, Lorena, Maria Aguilera, Grecinos, Gustavo, Mersich, Tamas, Wettstein, Daniel, Ghosh, Dhruv, Kembuan, Gabriele, Brouk, Peiman, Khosravi, Mohammad, Mozafari, Masoud, Adil, Ahmed, Mohan, Helen M., Zmora, Oded, Fiore, Marco, Gallo, Gaetano, Pata, Francesco, Pellino, Gianluca, Satoi, Sohei, Ayasra, Faris, Chaar, Mohammad, Fakhradiyev, Ildar R., Jamal, Mohammad, Elhadi, Muhammed, Gulla, Aiste, Roslani, April, Martinez, Laura, Ramos De La Medina, Antonio, Outani, Oumaima, Jonker, Pascal, Kruijff, Schelto, Noltes, Milou, Steinkamp, Pieter, van der Plas, Willemijn, Ademuyiwa, Adesoji, Osinaike, Babatunde, Seyi-olajide, Justina, Williams, Emmanuel, Pejkova, Sofija, Augestad, Knut Magne, Soreide, Kjetil, Al Balushi, Zainab, Qureshi, Ahmad, Sayyed, Raza, Mohsen Daraghmeh, Mustafa Abu, Abukhalaf, Sadi, Cukier, Moises, Gomez, Hugo, Shu, Sebastian, Vasquez, Ximena, Parreno-Sacdalan, Marie Dione, Major, Piotr, Azevedo, José, Cunha, Miguel, Santos, Irene, Zarour, Ahmad, Bonci, Eduard-Alexandru, Negoi, Ionut, Efetov, Sergey, Litvin, Andrey, Ntirenganya, Faustin, AlAmeer, Ehab, Radenkovic, Dejan, Hong Xiang, Frederick Koh, Hoe, Chew Min, Chi Yong, James Ngu, Moore, Rachel, Nhlabathi, Ncamsile, Colino, Ruth Blanco, Bravo, Ana Minaya, Minaya-Bravo, Ana, Jayarajah, Umesh, Wickramasinghe, Dakshitha, Elmujtaba, Mohammed, Jebril, William, Rutegård, Martin, Sund, Malin, Isik, Arda, Leventoğlu, Sezai, Abbott, Tom EF., Benson, Ruth, Caruna, Ed, Chakrabortee, Sohini, Demetriades, Andreas, Desai, Anant, Drake, Thomas D., Edwards, John G., Evans, Jonathan P., Ford, Samuel, Fotopoulou, Christina, Griffiths, Ewen, Hutchinson, Peter, Jenkinson, Michael D., Khan, Tabassum, Knight, Stephen, Kolias, Angelos, Leung, Elaine, McKay, Siobhan, Norman, Lisa, Ots, Riinu, Raghavan, Vidya, Roberts, Keith, Schache, Andrew, Shaw, Richard, Shaw, Katie, Smart, Neil, Stewart, Grant, Sundar, Sudha, Vimalchandran, Dale, Wright, Naomi, Alshryda, Sattar, Alser, Osaid, Breen, Kerry, Ganly, Ian, Kaafarani, Haytham, Kendall, Brittany, Mashbari, Hassan, Al Naggar, Hamza, Mazingi, Dennis, Simoes, Joana F. F., Dajti, I., Valenzuela, J. I., Boccalatte, L. A., Gemelli, N. A., Smith, D. E., Dudi-Venkata, N. N., Kroon, H. M., Sammour, T., Roberts, M., Mitchell, D., Lah, K., Pearce, A., Morton, A., Dawson, A. C., Drane, A., Sharpin, C., Nataraja, R. M., Pacilli, M., Cox, D. R. A., Muralidharan, V., Riddiough, G. E., Clarke, E. M., Jamel, W., Qin, K. R., Pockney, P., Cope, D., Egoroff, N., Lott, N., Putnis, S., De Robles, S., Ang, Z., Mitteregger, M., Uranitsch, S., Stiegler, M., Seitinger, G., Aigner, F., Lumenta, D. B., Nischwitz, S. P., Richtig, E., Pau, M., Srekl-Filzmaier, P., Eibinger, N., Michelitsch, B., Fediuk, M., Papinutti, A., Seidel, G., Kahn, J., Cohnert, T. U., Messner, F., Öfner, D., Presl, J., Varga, M., Weitzendorfer, M., Emmanuel, K., Binder, A. D., Zimmermann, M., Holawe, S., Nkenke, E., Grimm, C., Kranawetter, M., Rahman Mitul, A., Islam, N., Karim, S., Komen, N., Ang, E., De Praetere, H., Tollens, T., Schols, G., Smets, C., Haenen, L., Quintens, J., Van Belle, K., Van Ramshorst, G. H., Pattyn, P., Desender, L., Martens, T., Van de putte, D., Lerut, P., Grimonprez, A., Janssen, M., De Smul, G., Wallaert, P., Van den Eynde, J., Oosterlinck, W., Van den Eynde, R., Sermon, A., Boeckxstaens, A., Cordonnier, A., De Coster, J., Jaekers, J., Politis, C., Miserez, M., Duchateau, N., De Gheldere, C., Flamey, N., Christiano, A., Guidi, B., Minussi, A. L., Castro, S., Okoba, W., Maldonado, F. H. R., Oliveira, P., Baldasso, T., Santos, L., Gomes, G. M. A., Buarque, I. L., Pol-Fachin, L., Bezerra, T. S., Barros, A. V., da Silva, A. M. R., Leite, A. L. S., Silvestre, D. W. A., Ferro, C. C., Araujo, M. S., Lopes, L. M., Damasceno, P. D., Araujo, D. H. S., Laporte, G., Salem, M. C., Guimaraes-Filho, M. A. C., Nacif, L., Flumignan, R. L. G., Nakano, L. C. U., Kuramoto, D. A. B., Aidar, A. L. S., Pereda, M. R., Correia, R. M., Santos, B. C., Carvalho, A. A., Amorim, J. E., Guedes Neto, H. J., Areias, L. L., Sousa, A. F., Flumignan, C. D. Q., Lustre, W. G., Moreno, D. H., Barros, N., Baptista-Silva, J. C. C., Matos, L. L., Kowaski, L. P., Kulcsar, M. A. V., Nunes, K. S., Teixeira, M. F., Nunes, R. L., Ijichi, T. R., Kim, N. J., Marreiro, A., Muller, B., Barakat Awada, J., Baiocchi, G., Kowalski, L. P., Vartanian, J. G., Makdissi, F. B., Aguiar, S., Marques, N., Carvalho, G. B., Marques, T. M. D. M., Abdallah, E. A., Zurstrassen, C. E., Gross, J. L., Zequi, S. C., Gonçalves, B. T., Santos, S. S., Duprat, J. P., Coimbra, F. J. F., Cicco, R., Takeda, F., Cecconello, I., Ribeiro, U., Gatti, A., Oliva, R., Nardi, C., Slavchev, M., Atanasov, B., Belev, N., Dell, A., Bigam, D., Dajani, K., Al Riyami, S., Martin, J., Cheng, D., Yang, H., Fayad, A., Carrier, F. M., Amzallag, E., Desroches, J., Ruel, M., Caminsky, N. G., Boutros, M., Moon, J., Wong, E. G., Vanounou, T., Pelletier, J., Wong, S., Girsowicz, E., Bayne, J., Obrand, D., Gill, H., Steinmetz, O., MacKenzie, K., Lukaszewski, M., Jamjoum, G., Richebé, P., Verdonck, O., Discepola, S., Godin, N., Idrissi, M., Briatico, D., Sharma, S., Talwar, G., Bailey, K., Lecluyse, V., Côté, G., Demyttenaere, S., Garfinkle, R., Kouyoumdjian, A., Dumitra, S., Khwaja, K., Luo, L., Berry, G., Liberman, A. S., Schmid, S., Spicer, J., Al Farsi, M., Abou-Khalil, J., Couture, E., Mohammadi, S., Tremblay, H., Gagné, N., Bergeron, A., Turgeon, Af, Costerousse, O., Bellemare, D., Babin, C., Blier, C., Wood, M. L., Persad, A., Groot, G., Pham, H., D'Aragon, F., Carbonneau, E., Bouchard, M., Masse, M., Pesant, F., Héroux, J., Karanicolas, P., Hallet, J., Nadler, A., Nathens, A., Ko, M., Brar, A., Mayson, K., Kidane, B., Srinathan, S., Escudero, M. I., Reyes, J. T., Modolo, M. M., Ramirez Nieto, P., Sepulveda, R., Bolbarán, A., Molero, A., Ruiz, I., Reyes, G. P., Salas, R., Suazo, C., Muñoz, R., Grasset, E., Inzunza, M., Besser, N., Irarrázaval, M. J., Jarry, C., Bellolio, F., Romero Manqui, C. A., Ruiz Esquide, M., Fuentes, T., Campos, J., Perez Rivera, C. J., Cabrera, P. A., Pinilla, R. E., Guevara, O., Jimenez Ramirez, L. J., Velasquez Cuasquen, B. G., Herrera Mora, D. R., Bonilla, A., Diaz, S., Manrique, E., Facundo, H., Velez Bernal, J. L., Ángel, J., García, M., Guzmán, L., Lehmann, C., Cervera, S., Trujillo Sanchez, L. M., Guevara, R., Valbuena, D., Suarez, L., Jimenez, G., Velandia, A., Vargas, J., Espinosa, J., Rey, S., Mendoza Quevedo, Jairo, Calvache, J. A., Orozco-Chamorro, C. M., Sánchez-Gómez, T. A., Rojas-Tejada, D. A., Mihanovic, J., Bakmaz, B., Rakvin, I., Sulen, N., Andabaka, T., Luksic, I., Mamic, M., Martinek, L., Skrovina, M., Žatecký, J., Peteja, M., Kristensen, H. Ø., Mekhael, M., Christensen, P., Westh, L., Smith, H., Haugstvedt, A. F., Jönsson, M. L., Crespo, A., Batista, S., Rodriguez-Abreu, J., Tactuk, N., Diaz-Delgado, P. J., Rivas, R., Sarmiento-Bobadilla, J. A., Ashoush, F., Samir Abdelaal, A., Qatora, M. S., Elsayed Hewalla, M. E., Metwalli, M., Atta, R., Abdelmajeed, A., Abosamak, N. E., Sabry, A., Shehata, S., Sallam, I., Amira, G., Sherief, M., Sherif, A., Salem, H., Hamdy, R., Aboulkassem, H., Ghaly, G., Sherif, G., Morsi, A., Abdelrahman, A., Omnia, Ahmed, Tawheed, A., El Kassas, M., Omar, W., Abdelsamed, A., Seleim, A., Azzam, A. Y., ElFiky, M., Nabil, A., Ibraheem, M., ELDeeb, M., Fawzy, M., Hamed, H., Emile, S., Elfallal, A., Elfeki, H., Shalaby, M., Sakr, A., Alrahawy, M., Atif, H., Soltan, H., Sayed, A. K., Salah, A., Atiya, A., Wassim, K., Abbas, A. M., Abd Elazeem, H. A. S., Abd-Elkariem, A. Y., Abd-Elkarem, M. M., Alaa, S., Ali, A. K., Ashraf, M., Ayman, A., Azizeldine, M. G., Elkhayat, H., Emad Mashhour, A., Gaber, M., Hamza, H. M., Hawal, I., Hetta, H. F., Elghazaly, S. M., Mohammed, M. M., Monib, F. A., Nageh, M. A., Saad, A., Saad, M. M., Shahine, M., Yousof, E. A., Youssef, A., Esmail, E., Khalaf, M., Eldaly, A., Ghoneim, A., Hawila, A., Badr, H., Elhalaby, I., Abdel-bari, M., Elbahnasawy, M., Hamada, M. K., Morsy, M. S., Hammad, M., Essa, M., Fayed, M. T., Elzoghby, M., Rady, M., Hamad, O., Salman, S., Sarsik, S., Abd-elsalam, S., Gamal Badr, S., El-Masry, Y., Moahmmed, M. M. H., Hailu, S., Wolde, A., Mengesha, M., Nida, S., Workneh, M., Y Ahmed, M., Fisseha, T., Kassa, D., Zeleke, H., Admasu, A., Laeke, T., Tirsit, A., Gessesse, M., Addissie, A., Bekele, D., Kauppila, J. H., Sarjanoja, E., Testelin, S., Dakpé, S., Devauchelle, B., Bettoni, J., Lavagen, N., Schmitt, F., Lemée, J. M., Boucher, S., Breheret, R., Kün-Darbois, J. D., Kahn, A., Gueutier, A., Bigot, P., Borraccino, B., Lakkis, Z., Doussot, A., Heyd, B., Manfredelli, S., Mathieu, P., Paquette, B., Turco, C., Barrabe, A., Louvrier, A., Moszkowicz, D., Giovinazzo, D., Bretagnol, F., Police, A., Charre, L., Volpin, E., Braham, H., El Arbi, N., Villefranque, V., Bendjemar, L., Girard, E., Abba, J., Trilling, B., Chebaro, A., Lecolle, K., Truant, S., El Amrani, M., Zerbib, P., Pruvot, F. R., Mathieu, D., Surmei, E., Mattei, L., Marin, H., Christou, N., Ballouhey, Q., Ferrero, P., Coste Mazeau, P., Tricard, J., Barrat, B., Taibi, A., Usseglio, J., Laloze, J., Salle, H., Fourcade, L., Duchalais, E., Regenet, N., Rigaud, J., Waast, D., Denis, W., Malard, O., Buffenoir, K., Espitalier, F., Ferron, C., Varenne, Y., Crenn, V., De Vergie, S., Cristini, J., Samarut, E., Tzedakis, S., Bouche, P. A., Gaujoux, S., Kantor, E., Gossot, D., Seguin-Givelet, A., Fuks, D., Grigoroiu, M., Sanchez Salas, R., Cathelineau, X., Macek, P., Barbé, Y., Rozet, F., Barret, E., Mombet, A., Cathala, N., Brian, E., Zadegan, F., Conso, C., Blanc, T., Broch, A., Sarnacki, S., Ali, L., Bonnard, A., Peycelon, M., Hervieux, E., Clermidi, P., Maisonneuve, E., Aubry, E., Thomin, A., Langlais, T., Passot, G., Glehen, O., Cotte, E., Lifante, J. C., De Simone, B., Chouillard, E., Arnaud, A. P., Violas, P., Bergeat, D., Merdrignac, A., Scalabre, A., Perotto, L. O., Le Roy, B., Haddad, E., Vermersch, S., Ezanno, A. C., Barbier, O., Vigouroux, F., Malgras, B., Aime, A., Seeliger, B., Mutter, D., Philouze, G., Pessaux, P., Germain, A., Chanty, H., Ayav, A., Kassir, R., Von theobald, P., Sauvat, F., O'Connor, J., Mayombo Idiata, M., O'Connor, Z., Tchoba, S., Modabber, A., Winnand, P., Hölzle, F., Sommer, B., Shiban, E., Wolf, S., Anthuber, M., Sommer, F., Kaemmerer, D., Schreiber, T., Kamphues, C., Lauscher, J. C., Schineis, C., Loch, F. N., Beyer, K., Nasser, S., Sehouli, J., Höhn, P., Braumann, C., Reinkemeier, F., Uhl, W., Weitz, J., Bork, U., Welsch, T., Praetorius, C., Korn, S., Distler, M., Fluegen, G., Knoefel, W. T., Vay, C., Golcher, H., Grützmann, R., Binder, J., Meister, P., Gallinat, A., Paul, A., Schnitzbauer, A. A., Thoenissen, P., El Youzouri, H., Schreckenbach, T., Nguyen, T. A., Eberbach, H., Bayer, J., Erdle, B., Sandkamp, R., Nitschke, C., Izbicki, J., Uzunoglu, F. G., Koenig, D., Gosau, M., Böttcher, A., Heuer, A., Klatte, T. O., Priemel, M., Betz, C. S., Burg, S., Möckelmann, N., Busch, C. J., Bewarder, J., Zeller, N., Smeets, R., Thole, S., Vollkommer, T., Speth, U., Stangenberg, M., Hakami, I., Boeker, C., Mall, J., Schardey, H. M., von Ahnen, T., von Ahnen, M., Brunner, U., Tapking, C., Kneser, U., Hirche, C., Jung, M., Kowalewski, K. F., Kienle, P., Reissfelder, C., Seyfried, S., Herrle, F., Hardt, J., Galata, C., Birgin, E., Rahbari, N., Vassos, N., Stoleriu, M. G., Hatz, R., Albertsmeier, M., Börner, N., Lampert, C., Werner, J., Kuehlmann, B., Prantl, L., Brunner, S. M., Schlitt, H. J., Brennfleck, F., Pfister, K., Oikonomou, K., Reinhard, T., Nowak, K., Ronellenfitsch, U., Kleeff, J., Delank, K. S., Michalski, C. W., Szabo, G., Widyaningsih, R., Stavrou, G. A., Bschorer, R., Mielke, J., Peschel, T., Königsrainer, A., Quante, M., Löffler, M. W., Yurttas, C., Doerner, J., Seiberth, R., Bouchagier, K., Klimopoulos, S., Paspaliari, D., Stylianidis, G., Syllaios, A., Baili, E., Schizas, D., Liakakos, T., Charalabopoulos, A., Zografos, C., Spartalis, E., Manatakis, D. K., Tasis, N., Antonopoulou, M. I., Xenaki, S., Xynos, E., Chrysos, E., Athanasakis, E., Tsiaousis, J., Lostoridis, E., Tourountzi, P., Tzovaras, G., Tepetes, K., Zacharoulis, D., Baloyiannis, I., Perivoliotis, K., Hajiioannou, J., Korais, C., Gkrinia, E., Skoulakis, C. E., Saratziotis, A., Koukoura, O., Symeonidis, D., Diamantis, A., Tsoulfas, G., Christou, C. D., Tooulias, A., Papadopoulos, V., Anthoulakis, C., Grimbizis, G., Zouzoulas, D., Tsolakidis, D., Tatsis, D., Christidis, P., Loutzidou, L., Ioannidis, O., Astreidis, I., Antoniou, A., Antoniadis, K., Vachtsevanos, K., Paraskevopoulos, K., Kalaitsidou, I., Alexoudi, V., Stavroglou, A., Mantevas, A., Michailidou, D., Grivas, T., Deligiannidis, D., Politis, S., Barrios Duarte, A., Portilla, A. L., Lowey, M. J., Recinos, G., Lopez Muralles, I., Siguantay, M. A., Estrada, E. E., Aguilera-Arévalo, M. L., Cojulun, J. M., Echeverría-Dávila, G., Marín, C., Icaza de Marín, G. C., Kok, S. Y., Joeng, H. K. M., Chan, L. L., Lim, D., Novak, Z., Echim, T., Suszták, N., Banky, B., Kembuan, G., Pajan, H., Islam, A. A., Rahim, F., Safari, H., Mozafari, M., Brouki Milan, P., Tizmaghz, A., Rezaei Tavirani, M., Ahmed, A., Hussein, R., Fleming, C., O'Brien, S., Kayyal, M. Y., Daly, A., Killeen, S., Corrigan, M., De Marchi, J., Hill, A., Farrell, T., Davis, N. F., Kearney, D., Nelson, T., Maguire, P. J., Barry, C., Farrell, R., Smith, L. A., Mohan, H. M., Mehigan, B. J., Mccormick, P., Larkin, J. O., Fahey, B. A., Rogers, A., Donlon, N., O'Sullivan, H., Nugent, T., Reynolds, J. V., Donohue, C., Shokuhi, P., Ravi, N., Fitzgerald, C., Lennon, P., Timon, C., Kinsella, J., Smith, J., Boyle, T., Alazawi, D., Connolly, E., Butt, W., Croghan, S. M., Manecksha, R. P., Fearon, N., Winter, D., Heneghan, H., Maguire, D., Gallagher, T., Conlon, K., Kennedy, N., Martin, S., Kennelly, R., Hanly, A., Ng, K. C., Fagan, J., Geary, E., Cullinane, C., Carrington, E., Geraghty, J., McDermott, E., Pritchard, R., McPartland, D., Boland, M., Stafford, A., Geoghegan, J., Elliott, J. A., Ridgway, P. F., Gillis, A. E., Bass, G. A., Neary, P. C., O'Riordan, J. M., Kavanagh, D. O., Reynolds, I. S., K, Conlon, Joyce, D. P., Boyle, E., Egan, B., Whelan, M., Elkady, R., Tierney, S., Connelly, T. M., Earley, H., Umair, M., O'Connell, C., Thomas, A. Z., Rice, D., Madden, A., Bashir, Y., Creavin, B., Cullivan, O., Owens, P., Canas-Martinez, A., Murphy, C., Pickett, L., Murphy, B., Mastrosimone, A., Beddy, D., Arumugasamy, M., Allen, M., Aremu, M., McCarthy, C., O’Connor, C., O'Connor, D. B., Kent, E., Malone, F., Geary, M., McKevitt, K. L., Lowery, A. J., Ryan, É. J., Aherne, T. M., Fowler, A., Hassanin, A., Hogan, A. M., Collins, C. G., Finnegan, L., Carroll, P. A., Kerin, M. J., Walsh, S. R., Nally, D., Peirce, C., Coffey, J. C., Cunningham, R. M., Tormey, S., Hardy, N. P., Neary, P. M., Muallem-Kalmovich, L., Kugler, N., Lavy, R., Zmora, O., Horesh, N., Vergari, R., Mochet, S., Barmasse, R., Usai, A., Morelli, L., Picciariello, A., Papagni, V., Altomare, D. F., Colledan, M., Zambelli, M. F., Tornese, S., Camillo, A., Rausa, E., Bianco, F., Lucianetti, A., Prucher, G. M., Baietti, A. M., Ruggiero, F., Maremonti, P., Neri, F., Ricci, S., Biasini, M., Zarabini, A. G., Belvedere, A., Bernante, P., Bertoglio, P., Boussedra, S., Brunocilla, E., Cipriani, R., Cisternino, G., De Crescenzo, E., De Iaco, P., Della Gatta, A. N., Dondi, G., Frio, F., Jovine, E., Mineo Bianchi, F., Neri, J., Parlanti, D., Perrone, A. M., Pezzuto, A. P., Pignatti, M., Pilu, G., Pinto, V., Poggioli, G., Ravaioli, M., Rottoli, M., Schiavina, R., Serenari, M., Serra, M., Solli, P., Taffurelli, M., Tanzanu, M., Tesei, M., Violante, T., Zanotti, S., Tonini, V., Sartarelli, L., Cervellera, M., Gori, A., Armatura, G., Scotton, G., Patauner, S., Frena, A., Podda, M., Pisanu, A., Esposito, G., Frongia, F., Abate, E., Laface, L., Casati, M., Schiavo, M., Casiraghi, T., Sammarco, G., Gallo, G., Vescio, G., Fulginiti, S., Scorcia, V., Giannaccare, G., Carnevali, A., Giuffrida, M. C., Marano, A., Palagi, S., Di Maria Grimaldi, S., Testa, V., Peluso, C., Borghi, F., Simonato, A., Puppo, A., D'Agruma, M., Chiarpenello, R., Pellegrino, L., Maione, F., Cianflocca, D., Pruiti Ciarello, V., Giraudo, G., Gelarda, E., Dalmasso, E., Abrate, A., Daniele, A., Ciriello, V., Rosato, F., Garnero, A., Leotta, L., Giacometti, M., Zonta, S., Lomiento, D., Taglietti, L., Dester, S., Compagnoni, B., Viotti, F., Cazzaniga, R., Del Giudice, R., Mazzotti, F., Pasini, F., Ugolini, G., Fabbri, N., Feo, C. V., Righini, E., Gennari, S., Chiozza, M., Anania, G., Urbani, A., Koleva Radica, M., Carcoforo, P., Portinari, M., Sibilla, M., Anastasi, A., Bartalucci, B., Bellacci, A., Canonico, G., Capezzuoli, L., Di Martino, C., Ipponi, P., Linari, C., Montelatici, M., Nelli, T., Spagni, G., Tirloni, L., Vitali, A., Agostini, C., Alemanno, G., Bartolini, I., Bergamini, C., Bruscino, A., Checcucci, C., De Vincenti, R., Di Bella, A., Fambrini, M., Fortuna, L., Maltinti, G., Muiesan, P., Petraglia, F., Prosperi, P., Ringressi, M. N., Risaliti, M., Sorbi, F., Taddei, A., Lizzi, V., Vovola, F., Arminio, A., Cotoia, A., Sarni, A. L., Familiari, P., D'Andrea, G., Picotti, V., Bàmbina, F., Fontana, T., Barra, F., Ferrero, S., Gustavino, C., Kratochwila, C., Ferraiolo, A., Costantini, S., Batistotti, P., Aprile, A., Almondo, C., Ball, L., Robba, C., Scabini, S., Pertile, D., Massobrio, A., Soriero, D., D'Ugo, S., Depalma, N., Spampinato, M. G., Lippa, L., Gambacciani, C., Santonocito, O. S., Aquila, F., Pieri, F., Ballabio, M., Bisagni, P., Longhi, M., Armao, T., Madonini, M., Gagliano, A., Pizzini, P., Costanzi, A., Confalonieri, M., Monteleone, M., Colletti, G., Frattaruolo, C., Mari, G., Spinelli, A., Mercante, G., Spriano, G., Gaino, F., Ferreli, F., De Virgilio, A., Rossi, V., Carvello, M. M., Di Candido, F., Kurihara, H., Marrano, E., Torzilli, G., Castoro, C., Carrano, F. M., Martinelli, F., Macchi, A., Fiore, M., Pasquali, S., Cioffi, S. P. B., Baia, M., Abatini, C., Sarre, C., Mosca, A., Biasoni, D., Gronchi, A., Citterio, D., Mazzaferro, V., Cadenelli, P., Gennaro, M., Capizzi, V., Guaglio, M., Sorrentino, L., Bogani, G., Sarpietro, G., Giannini, L., Comini, L. V., Rolli, L., Folli, S., Raspagliesi, F., Piazza, C., Cosimelli, M., Salvioni, R., Antonelli, B., Baldari, L., Boni, L., Cassinotti, E., Pignataro, L., Rossi, G., Torretta, S., Beltramini, G. A., Gianni', A., Tagliabue, M., De Berardinis, R., Pietrobon, G., Chu, F., Cenciarelli, S., Adamoli, L., Ansarin, M., Fumagalli Romario, U., Mastrilli, F., Mariani, N. M., Nicastro, V., Cellerino, P., Colombo, F., Frontali, A., Bondurri, A., Guerci, C., Maffioli, A., Ferrario, L., Candiani, M., Bonavina, G., Ottolina, J., Valsecchi, L., Mortini, P., Gagliardi, F., Piloni, M., Medone, M., Negri, G., Bandiera, A., De Nardi, P., Sileri, P., Carlucci, M., Pelaggi, D., Rosati, R., Vignali, A., Parise, P., Elmore, U., Tamini, N., Nespoli, L. C., Rennis, M., Pitoni, L., Chiappetta, M. F., Vico, E., Fruscio, R., Grassi, T., Sasia, D., Migliore, M., Gattolin, A., Rimonda, R., Travaglio, E., Olearo, E., Tufo, A., Marra, E., Maida, P., Marte, G., Tammaro, P., Incollingo, P., Izzo, F., Belli, A., Patrone, R., Albino, V., Leongito, M., Granata, V., Piccirillo, M., Palaia, R., Francone, E., Gentilli, S., Nikaj, H., Fiorini, A., Norcini, C., Chessa, A., Marino, M. V., Mirabella, A., Vaccarella, G., Musini, L., Ampollini, L., Bergonzani, M., Varazzani, A., Bellanti, L., Domenichini, M., Cabrini, E., Fornasari, A., Freyrie, A., Dejana, D. O., D'Angelo, G., Bertoli, G., Di Lella, F., Bocchialini, G., Falcioni, M., Lanfranco, D., Poli, T., Giuffrida, M., Annicchiarico, A., Perrone, G., Catena, F., Raffaele, A., De Manzoni Garberini, A., Baldini, E., Conti, L., Ribolla, M., Capelli, P., Isolani, S. M., Maniscalco, P., Cauteruccio, M., Ciatti, C., Puma Pagliarello, C., Gattoni, S., Galleano, R., Malerba, M., Ciciliot, M., Farnesi, F., Calabrò, M., Pipitone Federico, N. S., Lunghi, E. G., Muratore, A., Di Franco, G., Palmeri, M., Tartaglia, D., Coccolini, F., Chiarugi, M., Simoncini, T., Gadducci, A., Caretto, M., Giannini, A., Perutelli, A., Domenici, L., Garibaldi, S., Capanna, R., Andreani, L., Furbetta, N., Guadagni, S., Bianchini, M., Gianardi, D., Pinotti, E., Montuori, M., Carissimi, F., Baronio, G., Zizzo, M., Castro Ruiz, C., Annessi, V., Montella, M. T., Falco, G., Mele, S., Ferrari, G., Mastrofilippo, V., Mandato, V. D., Aguzzoli, L., Corbellini, C., Baldi, C., Sampietro, G. M., Palini, G. M., Zanini, N., Garulli, G., Barone, R., Murgese, A., Mungo, S., Grasso, M., Marafante, C., Birolo, S. L., Moggia, E., Caccetta, M., Masciandaro, A., Deirino, A., Garino, M., Perinotti, R., Maiello, F., Gordini, L., Lombardi, C. P., Marzi, F., Marra, A. A., Ratto, C., Di Muro, M., Litta, F., De Simone, V., Cozza, V., Rosa, F., Agnes, A., Parello, A., Alfieri, S., Sganga, G., Lapolla, P., Mingoli, A., De Toma, G., Fiori, E., La Torre, F., Sapienza, P., Brachini, G., Cirillo, B., Iannone, I., Zambon, M., Chiappini, A., Meneghini, S., Fonsi, G. B., Cicerchia, P. M., Bruzzaniti, P., Santoro, A., Frati, A., Marruzzo, G., Ribuffo, D., Sagnotta, A., Marino Cosentino, L., Mancini, S., Lisi, G., Spoletini, D., Bellato, V., Campanelli, M., Sica, G., Siragusa, L., Bonavina, L., Asti, E., Bernardi, D., Lovece, A., Perra, T., Porcu, A., Fancellu, A., Feo, C. F., Scanu, A. M., Tuminello, F., Franceschi, A., Langone, A., Fleres, F., Spolini, A., Bordoni, P., Franzini, M., Clarizia, G., Grechi, A., Longhini, A., Guaitoli, E., Manca, G., Grossi, U., Novello, S., Zanus, G., Romano, M., Rossi, S., Ferrara, F., La Torre, M., Pirozzolo, G., Recordare, A., Paiella, S., Turri, G., Rattizzato, S., Campagnaro, T., Guglielmi, A., Pedrazzani, C., Ruzzenente, A., Poletto, E., Conci, S., Casetti, L., Fontana, M., Salvia, R., Malleo, G., Esposito, A., Landoni, L., De Pastena, M., Bassi, C., Tuveri, M., Nobile, S., Marchegiani, G., Bortolasi, L., Sambugaro, E., Malavolta, M., Moretto, G., Impellizzeri, H., Inama, M., Barugola, G., Ascari, F., Ruffo, G., Granieri, S., Cotsoglou, C., Berselli, M., Desio, M., Marchionini, V., Cocozza, E., Di Saverio, S., Ietto, G., Iovino, D., Carcano, G., Ayasra, F., Qasem, A., Ayasra, Y., Al-Masri, M., Abou Chaar, M. K., Al-Najjar, H., Ghandour, K., Alawneh, F., Abdel Jalil, R., Abdel Al, S., Elayyan, M., Ghanem, R., Lataifeh, I., Alsaraireh, O., Abu Za’nouneh, F. J., Fahmawee, T., Ibrahim, A., Obeidat, K., Lee, K. J., Shin, S. J., Chung, H., Albader, I., Alabbad, J., Albader, M. A. S., Bouhuwaish, A., Taher, A. S., Omar, M. S. M., Abdulwahed, E., Biala, M., Morgom, M., Elhadi, A., Alarabi, A., Msherghi, A., Elhajdawe, F., Alsoufi, A., Salamah, A., Salama, H., Bulugma, M., Almabrouk, H., Venskutonis, D., Dainius, E., Kubiliute, E., Bradulskis, S., Parseliunas, A., Kutkevicius, J., Subocius, A., Cheong, Y. J., Masood, M. S., Ngo, C. W., Saravanan, R., Abdul Maei, N., Hayati, F., Amin Sahid, N., Yanowsky Reyes, G., Orozco Perez, J., Damian, R., Santana Ortiz, R., Colunga Tinajero, C. A., Cordera, F., Gómez-Pedraza, A., Maffuz-Aziz, A., Posada, J. A., De la Rosa Abaroa, M. A., Alvarez, M. R., Arrangoiz, R., Hernández, R., Bozada Gutierrez, K., Trejo-Avila, M., Valenzuela-Salazar, C., Herrera-Esquivel, J., Moreno-Portillo, M., Pinto-Angulo, V. M., Sosa-Duran, E. E., Ziad-Aboharp, H., Jimenez Villanueva, X., Soulé Martínez, C. E., Lupián-Angulo, A. I., Martínez Zarate J, Jacobo, Reyes Rodriguez, E., Montalvo Dominguez, G., Becerra García, F. C., Melchor-Ruan, J., Vilar-Compte, D., Romero-Bañuelos, E., Herrera-Gomez, A., Meneses-Garcia, A., Isla-Ortiz, D., Salcedo-Hernández, R. A., Hernández-Nava, J. M., Morales-Castelan, J. E., Posadas-Trujillo, O. E., Buerba, G. A., Alfaro-Goldaracena, A., Pena Gomez-Portugal, E., Lopez-Pena, G., Hinojosa, C. A., Mercado, M. A., Ramos-De la Medina, A., Martinez, L., Duran, I., Gonzalez, D. S., Martinez, M. J., Nayen Sainz de la Fuente, A., Miguelena, L., Hernández Miguelena, L., Louraoui, S. M., El Azhari, A., Rghioui, M., Khya, E., Ghannam, A., Souadka, A., El Ahmadi, B., Belkhadir, Z. H., Majbar, M. A., Benkabbou, A., Mohsine, R., Oudrhiri, M. Y., Bechri, H., Arkha, Y., El Ouahabi, A., Frima, H., Bachiri, S., Groen, L. C., Verhagen, T., ter Brugge, F. M., Scheijmans, J. C. G., Boermeester, M. A., Hompes, R., Meima-van Praag, E. M., Sharabiany, S., Borgstein, A. B. J., Gisbertz, S. S., van Berge Henegouwen, M. I., Gans, S., Van Duijvendijk, P., Herklots, T., De Hoop, T., De Graaff, M. R., Sloothaak, D., Bolster-van Eenennaam, M., Baaij, J., Klinkenbijl, J. H. G., Van Eekeren, R., Spillenaar Bilgen, E. J., Van der Burg, S. W., Harlaar, N. J., Jonker, F. H. W., Vermaas, M., Voigt, K. R., Nellensteijn, D., Bensi, E. A. B., Posma-Bouman, L., Van Sambeek, M., Holscher, M., Van den den Broek, W. T., HKruijff, S., De Vries, J. P. P. M., Steinkamp, P. J., Jonker, P. K. C., Van der Plas, W. Y., Bierman, W., Janssen, Y., Franken, J., Oosterling, S., Boerma, E. G., Schweitzer, D., Keulen, M. H. F., Ketting, S., Wegdam, J. A., Vries Reilingh, T. S., de Schipper, Teeuwen, P. H. E., Hendriks, E. R., Van Geloven, A. A. W., Emous, M., Poelstra, R., Teunissen, M., Gerritsen, S. L., Boerma, D., De Reuver, P. R., Thunnissen, F., Vermeulen, B. A. M., Groen, A., Van Ginhoven, T. M., Viëtor, C. L., van der Oest, M. J. W., Vriens, P. W. H. E., Houwen, T., Heisterkamp, J., van Petersen, A. S., van der Meij, W., Stevens, C. T., Pronk, A., Bakker, W. J., Richir, M. C., Vriens, M. R., Filipe, M. D., Uittenbogaart, M., Leclercq, W. K. G., Sijmons, J. M. L., Vancoillie, P. J., Konsten, J., Van Heinsbergen, M., Dekker, N. A. M., den Boer, F. C., Akinmade, A., Adeyeye, A., Enoch, E., Fayose, S., Okunlola, A. I., Adeniyi, A. A., Adeyemo, O. T., Adebara, I. O., Bakare, A., Babalola, O. F., Abiyere, O. H., Banjo, O. O., Olori, S., Akaba, O. G., Agida, E. T., Abdullahi, I. H., Egbuchulem, I. K., Olulana, D., Lawal, T. A., Ogundoyin, O., Oyelakin, O. A., Nwaorgu, O. G., Sule, S. O., Makwe, C. C., Afolabi, B. B., Seyi-Olajide, J. O., Ademuyiwa, A. O., Bode, C. O., Atoyebi, O., Elebute, O. A., Okunowo, A. A., Williams, O. M., Eke, N. G., Oshodi, O. A., Faboya, O. M., Adeniran, A. S., Omisanjo, O. A., Oshodi, Y. A., Ogunyemi, A. A., Atobatele, K. M., Aremu, I., Olasehinde, O., Abdur-Rahman, L., Bello, J., Popoola, A., Sayomi, T. O., Raji, H. O., Adeleke, N., Lawal, B., Habeeb, O., Agodirin, O., Tolani, M. A., Sholadoye, T. T., Nwabuoku, S. E., Abubakar, M., Risteski, T., Cvetanovska Naunova, V., Jovcheski, L., Lazova, E., Agledahl, I., Breuer, R. G., Massoud, J., Waqar, S. H., Rashid, I., Ayubi, A., Bhatti, A. B. H., Younis, M. U., Ghouri, A., Ayub, B., Sayyed, R. H., Saleem, A., Turk, K., Alvi, A., Abassy, J., Khan, S., Arshad, M., Ahmed, K., Siddiqui, T., Pirzada, A., Kerawala, A. A., Jamal, A., Rai, L., Nafees Ahmed, R., Memon, A. S., Qureshi, A. U., Ayyaz, M., Umar, M., Butt, U., Kashif, M., Khan, W. H., Waris Farooka, M., Wasim, T., Talat, N., Tahir, W., Naseem, J., Akbar, A., Afroze, S., Sultan, A., Ali, H. B., Janjua, M. H., Janjua, A., Asghar, S., Farooq, M. S., Sarwar, M. Z., Naqi, S. A., Gondal, K. M., Bukhari, S. I., Tariq, M., Javed, S., Yaqoob, E., Mahmood, U., Raja Shabbir, K., Abukhalaf, S. A., Amro, A., Cabada Lee, J. M., Aguilar, A., Rodriguez, E., Castillo, K., Cukier, M., Rodriguez-Zentner, H., Arrue, E., Isaacs Beron, R., Rodríguez Gonzalez, A., Panduro-Correa, V., Cornelio, D. K., Otiniano Alvarado, C. E., Caballero Sarabia, V. D., Vasquez-Ojeda, X. P., Lizzetti-Mendoza, G., Niquen-Jimenez, M., Shu-Yip, S. B., León Palacios, J. L., Borda-Luque, G., Zegarra, S. A., Huamán Egoávil, E., Suazo Carmelo, C., Castro de la Mata, R., Rivas, D., Targarona, J., Trujillo, Y., Olivera Villanueva, M., Lahoud-Velaochaga, A., Cabillas, K., Castañeda, W., Colina Casas, J., Betalleluz Pallardel, J., Camacho Zacarías, F., Vélez Segura, E., Cruz Condori, D. L., Huamán, E., Ugarte Oscco, R., Vergel Cabrera, C., Carpio Colmenares, Y. T., García Barrionuevo, L. A., Cárdenas Ruiz de Castilla, D., Mansilla Doria, P., Li Valencia, M. R., Salazar, A., Sarmiento, A., Díaz, C., Morales, E., Ore, E., Zegarra, H., Siccha, J., Guardia, M., Sandoval, M., Mendiola, G. C., Mimbela, M., Diaz-Ruiz, R., Zeta, L. A., Cordova-Calle, E., Nuñez, H. M., Ortiz-Argomedo, M. R., Caballero-Alvarado, J., Salazar-Tantaleán, A., Espinoza-Llerena, R., Aliaga-Ramos, M., Asodisen, O., Jabagat, E., Tedoy, C. M., Ramos, R. A., Lopez, M. P. J., Violago, K. L. E., Aram, R., Carlos Santos, P., Filarca, R. F., Carlos, A., Santos, P., Filarca, R. L., Domingo, E. J., Khu, K. J. O., Lapitan, M. C., Sacdalan, M. D. P., Kho, M. J. N., Baticulon, R. E., Bravo, S. L. R., Cueto, M. A. C., Ramos, C. L., Fuentes, J. R., Sadian, H., Gumarao, A., Barraquio, A., Cruz, E. M., Gonzales, A. D., Reyes, J. A. S., Salud, J. A., Tancinco, E. G., Rivera, R. D., Lim, J. A., Barcelon, J. C., Chiu, J. A., Carballo, M. I., Major, P., Gawron, I., Jach, R., Borges, F., Matos Costa, P., Henriques, S., Rodrigues, S. C., Gonçalves, N., Curvas, J. M., Cabeleira, A., Branco, C., Serralheiro, P., Alves, R., Teles, T., Lázaro, A., Canhoto, C., Simões, J., Costa, M., Almeida, A. C., Nogueira, O., Oliveira, A., Athayde Nemésio, R., Silva, M., Lopes, C., Amaral, M. J., Valente da Costa, A., Andrade, R., Martins, R., Guimarães, A., Guerreiro, P., Ruivo, A., Camacho, C., Duque, M., Santos, E., Breda, D., Oliveira, J. M., De Oliveira Lopez, A. L., Garrido, S., Colino, M., De Barros, J., Correia, S., Rodrigues, M., Cardoso, P., Teixeira, J., Soares, A. P., Morais, H., Pereira, R., Revez, T., Manso, M. I., Domingues, J. C., Henriques, P., Ribeiro, R., Ribeiro, V. 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S., Matute-Najarro, M., Herrero-Lopez, M., Sanchez-Rubio, M., Cantalejo-Diaz, M., Gonzalez-Nicolas-Trebol, M. T., Saudi-Moro, S., Jariod-Ferrer, U. M., Rivas, F., Escartin, J., Blas Laina, J. L., Nogués, A., Cros, B., Talal El-Abur, I., Garcia Egea, J., Yanez, C., Jayarajah, U., Ravindrakumar, S., Rodrigo, V. S. D., Arulanantham, A., Bandara, G. B. K. D., Hamid, H. K. S., Ali, E. E., Widatalla, A. B. H., Bakheit, I., Awadelkarim, M., Ali karar, A. A., Saleh, M., Taflin, H., Myrelid, P., Amorim Braz, L., Hagander, L., Hambraeus, M., Omling, E., Salö, M., Arkani, S., Freedman, J., Montan, C., Lindqvist, E. K., Elbe, P., Hultgren, R., Älgå, A., Nordberg, M., Sandblom, G., Rutegård, M., Holmner, F., Sund, M., Löfgren, N., Tampakis, A., Kollmar, O., von Fluee, M., Balaphas, A., Toso, C., Colucci, N., Popeskou, S. G., Gass, M., Scheiwiller, A., Metzger, J., Gialamas, E., Chevallay, M., Sauvain, M., Dwidar, O., Kiessling, S. Y., Stoeckli, S. 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A., Kocatas, A., Öğücü, H., Uslu, G., Arican, C., Tugmen, C., Aydin, C., Yesilyurt, D., Avci, E. K., Kebapçı, E., Kilinc, G., Sert, İ., Tuncer, K., Akalin, M., Emiroglu, M., Demirli Atici, S., Salimoğlu, S., Kaya, T., Kirmizi, Y., Tatar, O. C., Yüksel, E., Güler, S. A., Yildirim, A., Utkan, N. Z., Gözal, K., Köken, H., Yabas, A., Gonullu, E., Altintoprak, F., Akin, E., Kamburoglu, B., Capoglu, R., Kucuk, F., Demir, H., Cakmak, G., Firat, N., Celebi, F., Kocer, B., Mantoglu, B., Bayhan, Z., Dikicier, E., Colak, E., Kucuk, G. O., Karaman, E., Kolusab, A., Karaaslan, O., Majid, I., Alshryda, S., Abbas, F., Abbas, F. M. A., Mohammed, D., Tahlak, M. A., Yammahi, A., Albaroudi, A. A., Elyafawi, B., Saber, A., Khansaheb, H., Alsaadi, H., Alzarooni, N., Bekheit, M., Kamera, B. S., Elhusseini, M., Sharma, P., Ahmeidat, A., Gradinariu, G., Cymes, W., Hannah, A., Mignot, G., Shaikh, S., Agilinko, J., Angelou, D., Neely, D., McCanny, A., McAree, B., Baldwin, A. J., West, R., Gammeri, E., Catton, A., Marinos Kouris, S., Pereca, J., Singh, J., Seymour, Z., Jones, R., Leeson, S., Peevor, R., Lala, A. K., Houlden, C., Kahiu, J., Hossain, N., Hosny, S., Patel, P., Handa, S., Kaushal, M., Kler, A., Reghuram, V., Tezas, S., Fairhurst, K., Yates, C., Mitchell, S., Bunni, J., Richards, S., George, R., Lee, S. M., Phull, J., Frost, J., Burnard, S., Crowley, R., Airey, A., Bevan, K., Makin-Taylor, R., Ong, C. S., Callan, R., Bloom, O., Aljanadi, F., Moawad, N., Jones, M., Gregg, A., Jeganathan, R., Pachl, M., Martin, B., Archer, J. E., Odeh, A., Siddaiah, N., Singhal, R., Naumann, D. N., Karandikar, S., Syed, A., Tucker, O. N., Alam, R., Kalkat, M., Mak, J. K. C., Kulkarni, R., Sharma, N., Nankivell, P., Tirotta, F., Parente, A., Breik, O., Kisiel, A., Cato, L. D., Saeed, S., Bhangu, A., Griffiths, E., Pathanki, A. M., Ford, S., Desai, A., Almond, M., Kamal, M., Sundar, S., Leung, E. Y. L., Kaur, R., Brett-Miller, C., Buruiana, F. E., Markose, G., De Gea Rico, A., Taib, A., Myatt, D., Sulaiman Khaled, A., Younis, F., Sultana, A., Taggarsi, M., Vitone, L., Lambert, J., Vaz, O. P., Sarantitis, I., Shrestha, D., Timbrell, S., Shugaba, A., Quddus, B., Law, J., Bittar, M. N., Creanga, M., Elniel, M., Youssef, M., Ali, S., Qadri, S. T., Brixton, G., Findlay, L., Klatte, T., Majkowska, A., Manson, J., Potter, R., Oktseloglou, V., Mosley, F., De La Cruz Monroy, M. F. I., Bobak, P., Omar, I., Ahad, S., Langlands, F., Brown, V., Hashem, M., Kennedy, L., Jaunoo, S., Coomber, E., Williams, O., Rhodes, H. L., Williams, A., Ridgway, A., Pournaras, D., Britton, E., Lostis, E., Ambler, G. K., Chu, H., Hopkins, J., Manara, J., Chan, M., Doe, M., Moon, R. D. C., Lawday, S., Jichi, T., Singleton, W., Main, B., Maccabe, T., Newton, C., Blencowe, N. S., Fudulu, D. P., Bhojwani, D., Baquedano, M., Caputo, M., Rapetto, F., Flannery, O., Hassan, A., Coonar, A., Aresu, G., Smith, C., Gearon, D., Hogan, J., Pradeep, I. S., Durio Yates, H., Peryt, A., Barrett-Brown, Z. M., King, M., Ahmadi, N., Jenkins, D., Moorjani, N., Taghavi, F., Wells, F., Hardie, J., Page, S., Anazor, F., King, S. D., Luck, J., Kazzaz, S., Mannion, R., Stewart, G. D., Ramzi, J., Mohan, M., Singh, A. A., Ashcroft, J., Baker, O. J., Coughlin, P., Davies, R. J., Durst, A. Z. E. D., Abood, A., Habeeb, A., Hudson, V. E., Kolias, A., Lamb, B., Luke, L., Mitrasinovic, S., Murphy, S., Ngu, A. W. T., O'Neill, J. R., Waseem, S., Wong, K., Georgiades, F., Hutchinson, P. J., Tan, X. S., Pushpa-rajah, J., Colquhoun, A., Masterson, L., Abu-Nayla, I., Walker, C., Balakrishnan, A., Rooney, S., Irune, E., Byrne, M. H. V., Durrani, A., Simoes, A., Eddy, B., Streeter, E., Ahmed, I., Yao, M., Wang, W., Djouani, A., Tait-Bailey, J., Thomas, M., Hassan, F., Kommu, S., Chopra, S., Richards, T., Sethuraman Venkatesan, A., Combellack, T., Williams, J., Tahhan, G., Mohammed, M., Kornaszewska, M., Valtzoglou, V., Deglurkar, I., Rahman, M., Von Oppell, U., Mehta, D., Koutentakis, M., Syed Nong Chek, S. A. H., Hill, G., Morris, C., Shinkwin, M., Torkington, J., Cornish, J., Houston, R., Mannan, S., Ayeni, F., Tustin, H., Bordenave, M., Robson, A., Dovell, G., Preece, R., Rolland, P., Miranda, B. H., Sobti, A., Khaleel, A., Unnithan, A., Memon, K., Pala Bhaskar, R. R., Maqboul, F., Kamel, F., Al-Samaraee, A., Madani, R., Kumar, L., Nisar, P., Agrawal, S., Vimalachandran, D., Manu, N., Eardley, N., Krishnan, E., Serevina, O. L., Martin, E., Jones, A., Roy Mahapatra, S., Clifford, R., Jones, G. P., Gardner, A., Tripathi, S. S., Greenhalgh, M. S., Matthews, W., Mohankumar, K., Khawaja, I., Palepa, A., Doulias, T., Gill, C., Dunne, N., Sarma, D. R., Godbole, C., Carlos, W., Tewari, N., Jeevan, D., Naredla, P., Khajuria, A., Connolly, H., Robertson, S., Sweeney, C., Di Taranto, G., Shanbhag, S., Dickson, K., McEvoy, K., Skillman, J., Sait, M., Al-omishy, H., Baig, M., Heer, B., Brown, A., Ebrahim, A., Alwadiya, A., Goyal, A., Phillips, A., Bhalla, A., Demetriou, C., Grimley, E., Theophilidou, E., Ogden, E., Malcolm, F. L., Davies-Jones, G., Ng, J. C. K., Mirza, M., Hassan, M., Elmaleh, N., Daliya, P., Williams, S., Bateman, A., Chia, Z., Premakumar, Y., Jauhari, Y., Koshnow, Z., Bowen, D., Uberai, A., Hirri, F., Stubbs, B. M., Crichton, R., Sonksen, J., Aldridge, K., McDonald, C., Manickavasagam, J., Ragupathy, K., Davison, S., Dalgleish, S., McGrath, N., Kanitkar, R., Payne, C. J., Ramsay, L., Ng, C. E., Collier, T., Khan, K., Evans, R., Brennan, C., Henshall, D. E., Drake, T., Harrison, E. M., Zamvar, V., Tambyraja, A., Skipworth, R. J. E., Linder, G., McGregor, R., Brennan, P., Mayes, J., Ross, L., Smith, S., White, T., Jamjoom, A. A. B., Pasricha, R., Gallagher, K., Swan, R., Paterson, H., Maeda, Y., Kwok, A. M. F., Tsiaousidou, A., Vaughan-Shaw, P. G., Boyle, C., Fernando, D., Tham, D., Leung, S., Laird, A., Holme, T., Abbott, S., Razik, A., Thrumurthy, S., Steinke, J., Baker, M., Howden, D., Baxter, Z., Osagie, L., Bence, M., Fowler, G. E., Massey, L., Rajaretnam, N., Evans, J., John, J., Goubran, A., Campain, N., McDermott, F. D., McGrath, J. S., Ng, M., Pascoe, J., Phillips, J. R. A., Daniels, I. R., A'Court, J., Konarski, A., Faulkner, G., Emerson, H., Vejsbjerg, K., Pearce, L., McCormick, W., Fisher, A., Singisetti, K., Aawsaj, Y., Bajomo, O., Rizvi, S., Grimes, C., Dusu, K., Tint, P. Y., Kirk, A., Irvine, V., Lammy, S., O'Kane, R., Elliott, L., Mccabe, G., Holroyd, D., Jamieson, N. B., Geddes, A., McMahon, J., McCaul, J., Al-Azzawi, M., Aitken, E., Glen, P., Sinan, L. O. H., Grivas, A., Tilling, E. J., Brown, O., Boal, M., Dean, H., Higgs, S., Stanger, S., Abdalaziz, H., Constable, J., Ishii, H., Gopi reddy, R., Madhuri, T. K., Tailor, A., Flavin, M., Walker, D., Humphries, S., Assalaarachchi, H., Curl-Roper, T., Westwood, E., Delimpalta, C., Liao, C. C. L., Velchuru, V., Raptis, D. A., Pollok, J. M., Machairas, N., Davidson, B., Fusai, G., Soggiu, F., Xyda, S., Hidalgo Salinas, C., Tzerbinis, H., Pissanou, T., Gilliland, J., Varcada, M., Hart, C., Mirnezami, R., Knowles, J., Angamuthu, N., Vijay, V., Shakir, T., Hasan, R., Tansey, R., Hardie, C., Powell-Smith, E., Kashora, F., Siddique, M. H., Singh, A., Barmpagianni, C., Basgaran, A., Basha, A., Okechukwu, V., Bartsch, A., Gallagher, P., Maqsood, A., Sahnan, K., Leo, C. A., Lewis, S. E., Ubhi, H. K., Exley, R., Khan, U., Shah, P., Saxena, S., Zafar, N., Abdul-Jabar, H., Patel, M., Shabana, A., Alanbuki, A., Usman, O., Ong, C. T., Butterworth, W., Budha Magar, O., El Hadi, M., Abas, S., Annett, J., Ross, E., Loubani, M., Wilkins, A., Cao, H., Capitelli-McMahon, H., Hitchman, L., Ikram, H., Andronic, A., Aboelkassem Ibrahim, A., Totty, J., Blanco, J., Vanker, R., Ghobrial, M., Jones, G., Kanthasamy, S., Fawi, H., Awadallah, M., Chen, F., Cheung, J., Moscalu, A., Bhuvanakrishna, T., Bibby, L., Sinclair, M., Nahid, M. A. K., Williams, L., Basnyat, P. S., Shrestha, A. K., Kumaran, N. K., Sambhwani, S., Sheikh, N. A., Taylor, O. M., Liew, I., Al-Sukaini, A., Mediratta, S., Saxena, D., Sgrò, A., Rashid, M. M., Milne, K., McIntyre, J., Akhtar, M. A., Turnbull, A., Brunt, A., Stewart, K. E., Wilson, M. S. J., Rutherford, D., McGivern, K., Massie, E., Ho, M., Wade, R. G., Johnstone, J., Bourke, G., Brunelli, A., Elkadi, H., Otify, M., Pompili, C., Burke, J. R., Bagouri, E., Chowdhury, M., Abual-Rub, Z., Kaufmann, A., Munot, S., Lo, T., Young, A., Kowal, M., Wall, J., Peckham-Cooper, A., Layton, G. R., Karki, B., Jeong, H., Pankhania, S., Asher, S., Folorunso, A., Mistry, S., Singh, B., Winyard, J., Mangwani, J., Caruana, E. J., Mohammad, A., Acharya, M., Chandarana, K., Ang, K., Chowdhry, M. F., Rathinam, S., Nakas, A., Boddy, A., Hossain, T., Ashmore, C., Annamalai, S., Kourdouli, A., Irvine, E., Al-Harbawi, A., Kassam, K., Al-Harbawee, A., Miller, A., Mair, M., Lunevicius, R., Sheel, A. R. G., Sundhu, M., Santini, A. J. A., Fathelbab, M. S. A. T., Hussein, K. M. A., Nunes, Q. M., Jones, R. P., Shahzad, K., Haq, I., Baig, M. M. A. S., Hughes, J. L., Kattakayam, A., Rajput, K., Misra, N., Shah, S. B., Clynch, A. L., Georgopoulou, N., Sharples, H. M., Apampa, A. A., Nzenwa, I. C., Sud, A., Harky, A., Kirmani, B. H., Shackcloth, M., Jenkinson, M. D., Zakaria, R., Elmoslemany, T., Millward, C. P., Baron, R., Dunne, D., Szatmary, P., Thomas, A., McNicol, F., Gahunia, S., Sochorova, D., Nita, G. E., McKinney, R., Russ, J., Tan, J. R., Harwood, R., Corbett, H. J., Rossborough, C., Skelly, B. L., Che Bakri, N. A., Nazarian, S., Vashisht, R., Jiao, L., Jawad, Z., Allan, A. Y., Kontovounisios, C., Grove, T., Warren, O., Fadel, M. G., Chatzikonstantinou, M., Sorelli, P., Rahman, S., Hadjipavlou, M., Holbrook, C., Chong, C., Kufeji, D., Rufai, S. R., Lloyd, I. C., James, G., Chari, A., Silva, A. H. D., Stroman, L., Challacombe, B., Sayasneh, A., Najdy, M., Billè, A., Fraser, S., Agoston, P., Rizzo, V., King, J., Nath, R., McCrindle, Sarah, Mehra, G., Harrison-Phipps, K., Pilling, J., Okiror, L., Routledge, T., Mills, L., Wali, A., El-Boghdadly, K., Fotopoulou, C., Saso, S., Fehervari, M., Ploski, J., Ghaem-Maghami, S., Spalding, D., Rajagopal, P., Pai, M., Habib, N., Hamrang-Yousefi, S., Tayeh, S., Chase, T., Humphreys, L., Ayorinde, J., Ghanbari, A., Cuming, T., Anscomb, N., Baldwin-Smith, R., Rizk, M., Grainger, C., Davies, M., Surendran, A., Nunoo-Mensah, J. W., Dunstan, M., Beak, P., Gerogiannis, I., Jain, A., Menon, A., Pramodana, B., Choi, D., Marcus, H. J., Webber, L., May, R., Hutchison, R., Luoma, V., Ranjit, S., Parakh, J., Sarodaya, V., Daadipour, A., Khalifa, M., Bosch, K. D., Bashkirova, V., Dvorkin, L. S., Kalidindi, V. K., Dudek, J., Singhal, T., El-Hasani, S., De Souza, A., Cannoletta, M., Rochon, M., Bhudia, S., Bennett, S., Navaratne, L., Venn, M., Yip, V., Kayani, B., Sohrabi, C., Kocher, H. M., Minicozzi, A., Banerjee, A., Sullivan, T., Sivaprakasam, R., Anzak, A., Ghufoor, K., Thaha, M. A., Knowles, C., Ledesma, F. S., Patki, P., Popova, D., Sadigh, P., Ramamoorthy, R., Uff, C., Attwell, L., Tanabalan, C., Goh, M. A., Jayasinghe, J. D., Leal Silva, I., Thakur, B., Lebe, M., Thet, M. S., Hughes, F., Rahman, R., Fuwa, O., Sanders, J., Oo, A., Bueser, T., Curtis, M., Stamenkovic, S. A., Abbott, T., Anwar, S., Williams, K., Chung, E., Hagger, R., Karim, A., Hainsworth, A., Flatman, M., Trompeter, A., Hing, C., Tsinaslanidis, P., Benjamin, M. W., Leyte, A., Tan, C., Smelt, J., Vaughan, P., Santhirakumaran, G., Hunt, I., Raza, M., Labib, A., Luo, X., Sudarsanam, A., Rolls, A., Lyons, O., Onida, S., Shalhoub, J., Sugand, K., Park, C., Sarraf, K. M., Erridge, S., Kinross, J., Denning, M., Yalamanchili, S., Abuown, A., Ibrahim, M., Martin, G., Davenport, D., Wheatstone, S., Kasivisvanathan, V., Kapriniotis, K., Elhamshary, A., Imam, S. M. B., Kalavrezos, N., Sinha, D., Chand, M., Green, L., Beech, N., McEwen, R., Kiconco, H., Andreani, S. M., Bath, M. F., Sahni, A., Judkins, N., Rigueros Springford, L., Bacarese-Hamilton, J., Taylor, F. G., Parmar, C., Mccluney, S., Shah, S., Talwar, R., Patel, K., Askari, A., Jambulingam, P. S., Shaw, S., Maity, A., Hatzantonis, C., Sagar, J., Kudchadkar, S., Cirocchi, N., Chan, C. H., Reynolds, J., Alexander, M. E., Smart, C. J., Jayasankar, B., Balasubramaniam, D., Abdelsaid, K., Mundkur, N., Gallagher, B., Shah, J., Anthoney, J., Emmerson, O., Stylianides, N., Abdalla, M., Newton, K., Bhatia, K., Edmondson, R., Abdeh, L., Jones, D., Zeiton, M., Ismail, O., Naseem, H., Advani, R., Duff, S., Moura, F., Brown, B. C., Khan, A., Asaad, P., Wadham, B., Aneke, I. A., Collis, J., Warburton, H., Fell, A., Smith, A., Halkias, C., Nikolaou, S., English, C., Kristinsson, S., Oni, T., Ilahi, N., Ballantyne, K., Woodward, Z., Merh, R., Dunning, J., Viswanath, Y., Freystaetter, K., Dixon, J., Hadfield, J. N., Hilley, A., Egglestone, A., Smith, B., Hine, T., Keeler, B., Soulsby, R. E., Taylor, A., Davies, E., Ryska, O., Raymond, T., Rogers, S., Tong, A., Hawkin, P., Tingle, S., Abbadessa, F., Sachdeva, A., Rai, B., Chan, C. D., McPherson, I., Booth, K., Mahmoud Ali, F., Pandanaboyana, S., Grainger, T., Nandhra, S., Patience, A., Roy, C., Williams, T., Dawe, N., McCaffer, C., Riches, J., Bhattacharya, S., Moir, J., Kalson, N. S., Elamin Ahmed, H., Mellor, C., Saleh, C., Koshy, R. M., Hammond, J., Sanderson, L., Wahed, S., Phillips, A. W., Ghosh, K., Tang, A., Beamish, A. J., Price, C., Bosanquet, D., Magowan, D., Solari, F., Williams, G., Nassa, H., Smith, L., Robertson-Smith, B., Mahmoud, A., Ameerally, P., Finch, J. G., Gnanachandran, C., Pop, I., Rogers, M., Yousef, Y., Mohamed, I., Woods, R., Zahid, H., Mundy, G., Sreedharan, L., Baskaran, D., Shaikh, I., Seebah, K., Reid, J., Watts, D., Kouritas, V., Chrastek, D., Maryan, G., Gill, D. F., Khatun, F., Gajjar, K., Williamson, K., Bratt, D., Konstantinidi, K., Walton, T., Burnside, N., Weaver, H., Hawari, M., Addae-Boateng, E., Rollett, R. A., Collins, M. L., Tamimy, M. S., Riyat, H., Wen, J., Neil-Dwyer, J., Brewer, H., Humes, D., Worku, D., Chowdhury, A., Oyende, O., Lewis-Lloyd, C., Adiamah, A., Koh, A., Jackman, J., Vohra, R., Navarro, A., Reilly, J., Aujayeb, A., Townshend, D., McLarty, N., Shenfine, A., Jackson, K., Johnson, C., Dass, D., Ford, D., Winter, S. C., Belcher, E., Stavroulias, D., Di Chiara, F., Wallwork, K., Qureishi, A., Lami, M., Sravanam, S., Mastoridis, S., Shah, K., Chidambaram, S., Smillie, R., Shaw, A. V., Bandyopadhyay, S., Cernei, C., Bretherton, C., Jeyaretna, D., Ganau, M., Piper, R. J., Duck, E., Brown, S., Jelley, C., Tucker, S. C., Bond-Smith, G., Griffin, X. L., Tebala, G. D., Neal, N., Vatish, M., Noton, T. M., Ghattaura, H., Maher, M., Fu, H., Risk, O. B. F., Soleymani majd, H., Sinha, S., Shankar, S., Aggarwal, A., Kharkar, H., Lakhoo, K., Verberne, C., Dean, B., Luney, C., Myatt, R., Williams, M. A., McVeigh, J., Rogers, L. J., Labib, P. L., Miller, D., Minto, G., Hope, N., Marchbank, A., Emslie, K., Panahi, P., Ho, B., Perkins, C., Clough, E., Roy, H., Enemosah, I., Campbell, R., Natale, J., Gohil, K., Rela, M., Raza, N., Biliatis, I., Khan, J., Thiruchandran, G., Toh, S. K. C., Ahmad, Y., Allana, A., Bellis, C., Babawale, O., Phan, Y. C., Lokman, U., Ismail, M., Koc, T., Witek, A., Duggleby, L., Shamoon, S., Stefan, S., Clancy, H., Chadha, R., Middleton, S. B., Wilmott, K., Hayden, C., Mclaren, C., Sutton, J., Whyte, A., Belgaumkar, A., Day, A., Gilbert, C., Oyewole, B., Narayan, P., Dent, H., Sandhya, A., De Silva, T., Waheed, S., Kapoor, K., Belgaumkar, A. P., Fahim, M., Gala, T., Mithany, R., Morgan, R., Abdelkarim, M., Maw, A., Asqalan, A., Sundaram Venkatesan, G., Singh, S., Mukherjee, S., Ferguson, D., Mansuri, A., Thakrar, A., Wickramarachchi, L., Cuthbert, R., Sivayoganathan, S., Chui, K., Karam, E., Dott, C., Madhvani, K., Hampton, M., Hormis, A. P., Fountain, D. M., Laurente, R., Sigamoney, K. V., Dasa, M., George, K., Naqui, Z., Galhoum, M., Lipede, C., Gabr, A., Radhakrishnan, A., Hasan, M. T., Kalenderov, R., Pathmanaban, O., Chelva, R., Branagan, G., Longstaff, L., Ding, D., Barlow, C., Foster, J., Edwards, J., Ward, A., Tadross, D., Majkowski, L., Blundell, C., Forlani, S., Nair, R., Guha, S., Brown, S. R., Steele, C., Kelty, C. J., Newman, T., Lee, M., Chetty, G., Lye, G., Balasubramanian, S. 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M., Elawad A., Alhefdhi A., Alresaini F., Kurdi W., Tulbah M., Aldakheel M., Alsahan N., Koussayer S., Elsheikh H., Al-qattan M., Alshanafey S., Rafique A., Mahabbat N., Saeed B., Al-Kharashi E., Alsowaina K., Arab N., Aljaber F., Al Hasan I., Alghamdi A., Badahdah F., Alghuliga A., Abdulfattah F., Alanazi F., Albaqami F., Alsuhaibani A., AlFakhri A., Alqasem S., Alajaji N., Nouh T., Bin Nasser A., Alowais J., Alburakan A., Alamri O., Albdah A., Alawi K., Alshalhoub M., ElSanhoury K., Almofarreh A., Ibrahim S., Elshafie H., Osman I., Guzman T., Mutair H., Siddiqui A., Chowdhury S., Alghamdi R., Almutrafi S., Alfaifi J., D'Souza J., Alshitwi A., Alkreedees N., Alramadhan M., Alshehri M., Alobaysi S., Alshahrani A., Alshehri A., Alrashed M., Altahan T., Alsabahi T., Alhossaini R., Sbaih M., Alalawi Y., Alnwijy K., Al Ayed A., Ghedan S., Alharthi R., Awad S., I Sharara M., Abdelrhman S., Althobaiti W., Srbinovic L., Perovic M., Mikovic Z., Nikolic B., Vasiljevic M., Pazin V., Mandic Markovic V., Dimitrijevic D., Zecevic N., Gregoric P., Micic D., Loncar Z., Doklestic K., Ivancevic N., Djukic V., Stojakov D., Ilic R., Savic P., Pijanovic N., Milanovic M., Radosavljevic M., Dejanovic T., Kostic M., Paskas J., Bojic S., Stevanovic P., Djuric M., Kadija M., Tulic G., Glisovic Jovanovic I., Lieske B., Kayombo E., Kruger I., De Kock M., Malan A., Ferreira C., Du Preez H., Mulder W., Noel C., Le Grange S., Lusawana O., Kies C., Steyn E., Janson J., Buitendag J.J.P., Chu K., Mihalik M., Nel R., Naidoo S., Kloppers C., Nel D., Jonas E., Pickard H., Bernon M., Almgla N., Rayamajhi S., Mugla W., Carapinha C., Hyman G.Y., Fourtounas M., Sanchez Mozo A., Aguado Lopez H., Zarate Pinedo A., Jimenez Toscano M., Alonso de la Fuente N., Mancebo G., Cecchini L., Munarriz M., Cazador Labat M., Lopez Campillo A., Martorell P., Espinosa C.A., Caja Vivancos P., Villalabeitia Ateca I., Prieto Calvo M., Martin Playa P., Gainza A., Aragon Achig E.J., Rodriguez Fraga A., Melchor Corcostegui 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A.Z.E.D., Abood A., Habeeb A., Hudson V.E., Lamb B., Luke L., Mitrasinovic S., Murphy S., Ngu A.W.T., O'Neill J.R., Waseem S., Wong K., Georgiades F., Hutchinson P.J., Tan X.S., Pushpa-rajah J., Colquhoun A., Masterson L., Abu-Nayla I., Walker C., Balakrishnan A., Rooney S., Irune E., Byrne M.H.V., Durrani A., Simoes A., Eddy B., Streeter E., Ahmed I., Yao M., Wang W., Djouani A., Tait-Bailey J., Thomas M., Hassan F., Kommu S., Chopra S., Richards T., Sethuraman Venkatesan A., Combellack T., Williams J., Tahhan G., Mohammed M., Kornaszewska M., Valtzoglou V., Deglurkar I., Rahman M., Von Oppell U., Mehta D., Koutentakis M., Syed Nong Chek S.A.H., Hill G., Morris C., Shinkwin M., Torkington J., Cornish J., Houston R., Mannan S., Ayeni F., Tustin H., Bordenave M., Robson A., Dovell G., Preece R., Rolland P., Miranda B.H., Sobti A., Khaleel A., Unnithan A., Memon K., Pala Bhaskar R.R., Maqboul F., Kamel F., Al-Samaraee A., Madani R., Kumar L., Nisar P., Agrawal S., Vimalachandran D., Manu 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Henshall D.E., Drake T., Harrison E.M., Zamvar V., Tambyraja A., Skipworth R.J.E., Linder G., McGregor R., Brennan P., Mayes J., Ross L., Smith S., White T., Jamjoom A.A.B., Pasricha R., Gallagher K., Swan R., Paterson H., Maeda Y., Kwok A.M.F., Tsiaousidou A., Vaughan-Shaw P.G., Boyle C., Fernando D., Tham D., Leung S., Laird A., Holme T., Abbott S., Razik A., Thrumurthy S., Steinke J., Baker M., Howden D., Baxter Z., Osagie L., Bence M., Fowler G.E., Massey L., Rajaretnam N., Evans J., John J., Goubran A., Campain N., McDermott F.D., McGrath J.S., Ng M., Pascoe J., Phillips J.R.A., Daniels I.R., A'Court J., Konarski A., Faulkner G., Emerson H., Vejsbjerg K., Pearce L., McCormick W., Fisher A., Singisetti K., Aawsaj Y., Bajomo O., Rizvi S., Grimes C., Dusu K., Tint P.Y., Kirk A., Irvine V., Lammy S., O'Kane R., Elliott L., Mccabe G., Holroyd D., Jamieson N.B., Geddes A., McMahon J., McCaul J., Al-Azzawi M., Aitken E., Glen P., Sinan L.O.H., Grivas A., Tilling E.J., Brown O., Boal M., 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A., Miller A., Mair M., Lunevicius R., Sheel A.R.G., Sundhu M., Santini A.J.A., Fathelbab M.S.A.T., Hussein K.M.A., Nunes Q.M., Jones R.P., Shahzad K., Haq I., Baig M.M.A.S., Hughes J.L., Kattakayam A., Rajput K., Misra N., Shah S.B., Clynch A.L., Georgopoulou N., Sharples H.M., Apampa A.A., Nzenwa I.C., Sud A., Harky A., Kirmani B.H., Shackcloth M., Zakaria R., Elmoslemany T., Millward C.P., Baron R., Dunne D., Szatmary P., Thomas A., McNicol F., Gahunia S., Sochorova D., Nita G.E., McKinney R., Russ J., Tan J.R., Harwood R., Corbett H.J., Rossborough C., Skelly B.L., Che Bakri N.A., Nazarian S., Vashisht R., Jiao L., Jawad Z., Allan A.Y., Kontovounisios C., Grove T., Warren O., Fadel M.G., Chatzikonstantinou M., Sorelli P., Rahman S., Hadjipavlou M., Holbrook C., Chong C., Kufeji D., Rufai S.R., Lloyd I.C., James G., Chari A., Silva A.H.D., Stroman L., Challacombe B., Sayasneh A., Najdy M., Bille A., Fraser S., Agoston P., Rizzo V., King J., Nath R., McCrindle S., Mehra G., 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M.A., Jayasinghe J.D., Leal Silva I., Thakur B., Lebe M., Thet M.S., Hughes F., Rahman R., Fuwa O., Oo A., Bueser T., Curtis M., Stamenkovic S.A., Abbott T., Anwar S., Williams K., Chung E., Hagger R., Karim A., Hainsworth A., Flatman M., Trompeter A., Hing C., Tsinaslanidis P., Benjamin M.W., Leyte A., Tan C., Smelt J., Vaughan P., Santhirakumaran G., Hunt I., Raza M., Labib A., Luo X., Sudarsanam A., Rolls A., Lyons O., Onida S., Shalhoub J., Sugand K., Park C., Sarraf K.M., Erridge S., Kinross J., Denning M., Yalamanchili S., Abuown A., Ibrahim M., Martin G., Davenport D., Wheatstone S., Kasivisvanathan V., Kapriniotis K., Elhamshary A., Imam S.M.B., Kalavrezos N., Sinha D., Chand M., Green L., Beech N., McEwen R., Kiconco H., Andreani S.M., Bath M.F., Sahni A., Judkins N., Rigueros Springford L., Bacarese-Hamilton J., Taylor F.G., Parmar C., Mccluney S., Shah S., Talwar R., Patel K., Askari A., Jambulingam P.S., Shaw S., Maity A., Hatzantonis C., Sagar J., Kudchadkar S., Cirocchi N., Chan C.H., Reynolds J., Alexander M.E., Smart C.J., Jayasankar B., Balasubramaniam D., Abdelsaid K., Mundkur N., Gallagher B., Shah J., Anthoney J., Emmerson O., Stylianides N., Abdalla M., Newton K., Bhatia K., Edmondson R., Abdeh L., Jones D., Zeiton M., Ismail O., Naseem H., Advani R., Duff S., Moura F., Brown B.C., Khan A., Asaad P., Wadham B., Aneke I.A., Collis J., Warburton H., Fell A., Smith A., Halkias C., Nikolaou S., English C., Kristinsson S., Oni T., Ilahi N., Ballantyne K., Woodward Z., Merh R., Dunning J., Viswanath Y., Freystaetter K., Dixon J., Hadfield J.N., Hilley A., Egglestone A., Smith B., Hine T., Keeler B., Soulsby R.E., Taylor A., Davies E., Ryska O., Raymond T., Rogers S., Tong A., Hawkin P., Tingle S., Abbadessa F., Sachdeva A., Rai B., Chan C.D., McPherson I., Booth K., Mahmoud Ali F., Pandanaboyana S., Grainger T., Nandhra S., Patience A., Roy C., Williams T., Dawe N., McCaffer C., Riches J., Bhattacharya S., Moir J., Kalson N.S., Elamin Ahmed H., Mellor C., Saleh C., Koshy R.M., Hammond J., Sanderson L., Wahed S., Phillips A.W., Ghosh K., Tang A., Beamish A.J., Price C., Bosanquet D., Magowan D., Solari F., Williams G., Nassa H., Smith L., Robertson-Smith B., Mahmoud A., Ameerally P., Finch J.G., Gnanachandran C., Pop I., Rogers M., Yousef Y., Mohamed I., Woods R., Zahid H., Mundy G., Sreedharan L., Baskaran D., Shaikh I., Seebah K., Reid J., Watts D., Kouritas V., Chrastek D., Maryan G., Gill D.F., Khatun F., Gajjar K., Williamson K., Bratt D., Konstantinidi K., Walton T., Burnside N., Weaver H., Hawari M., Addae-Boateng E., Rollett R.A., Collins M.L., Tamimy M.S., Riyat H., Wen J., Neil-Dwyer J., Brewer H., Humes D., Worku D., Chowdhury A., Oyende O., Lewis-Lloyd C., Adiamah A., Koh A., Jackman J., Vohra R., Navarro A., Reilly J., Aujayeb A., Townshend D., McLarty N., Shenfine A., Jackson K., Johnson C., Dass D., Ford D., Winter S.C., Belcher E., Stavroulias D., Di Chiara F., Wallwork K., Qureishi A., Lami M., Sravanam S., Mastoridis S., Shah K., Chidambaram S., Smillie R., Shaw A.V., Bandyopadhyay S., Cernei C., Bretherton C., Jeyaretna D., Ganau M., Piper R.J., Duck E., Brown S., Jelley C., Tucker S.C., Bond-Smith G., Griffin X.L., Tebala G.D., Neal N., Vatish M., Noton T.M., Ghattaura H., Maher M., Fu H., Risk O.B.F., Soleymani majd H., Sinha S., Shankar S., Aggarwal A., Kharkar H., Lakhoo K., Verberne C., Dean B., Luney C., Myatt R., Williams M.A., McVeigh J., Labib P.L., Miller D., Minto G., Hope N., Marchbank A., Emslie K., Panahi P., Ho B., Perkins C., Clough E., Roy H., Enemosah I., Campbell R., Natale J., Gohil K., Rela M., Raza N., Biliatis I., Khan J., Thiruchandran G., Toh S.K.C., Ahmad Y., Allana A., Bellis C., Babawale O., Phan Y.C., Lokman U., Ismail M., Koc T., Witek A., Duggleby L., Shamoon S., Stefan S., Clancy H., Chadha R., Middleton S.B., Wilmott K., Hayden C., Mclaren C., Sutton J., Whyte A., Belgaumkar A., Day A., Gilbert C., Oyewole B., Narayan P., Dent H., Sandhya A., De Silva T., Waheed S., Kapoor K., Belgaumkar A.P., Fahim M., Gala T., Mithany R., Morgan R., Abdelkarim M., Maw A., Asqalan A., Sundaram Venkatesan G., Singh S., Mukherjee S., Ferguson D., Mansuri A., Thakrar A., Wickramarachchi L., Cuthbert R., Sivayoganathan S., Chui K., Karam E., Dott C., Madhvani K., Hampton M., Hormis A.P., Fountain D.M., Laurente R., Sigamoney K.V., Dasa M., George K., Naqui Z., Galhoum M., Lipede C., Gabr A., Radhakrishnan A., Hasan M.T., Kalenderov R., Pathmanaban O., Chelva R., Branagan G., Longstaff L., Ding D., Barlow C., Foster J., Ward A., Tadross D., Majkowski L., Blundell C., Nair R., Guha S., Brown S.R., Steele C., Kelty C.J., Newman T., Lee M., Lye G., Balasubramanian S.P., Sureshkumar Shah N., Sherif M., Al-mukhtar A., Whitehall E., Giblin A., Sharkey A., Adamec A., Madan S., Narice B., Sterrenburg M., Thompson A., Varley I., Stavrakas M., Rominiyi O., Ray J., Crank M., Bacon A., Al-Tamimi Y., Catto J., Saad S., Abd Kahar N.N., Sou A., Simpson D., Hamilton E., Blair J., Jallad S., Lord J., Anderson C., El Kafsi J., Logishetty K., Saadya A., Midha R., Ip M., Subbiah Ponniah H., Stockdale T., Bacarese-Hamilton T., Foster L., James A., Anjarwalla N., Marujo Henriques D., Hettige R., Baban C., Tenovici A., Salerno G., Lane J., Colvin H.V., Badran A., Cadersa A., Cumpstey A., Hamady Z., Aftab R., Wensley F., Byrne J., Morrison-Jones V., Sekhon G.K., Shields H., Shakoor Z., Yener A., Talbot T., Alzetani A., Cresner R., Babu B.H.B., Liyanage A.S.D., Newman S., Blake I., Weerasinghe C., Baumber R., Parry J., Menakaya C., Webb J.I., Antar M., Modi N., Sofat R., Noel J., Nunn R., Adegbola S., Eriberto F., Sharma V., Tanna R., Lodhia S., Johnson D., Hughes I., Hall J., Rooney J., Chatterji S., Zhang Y., Owen R., Rudic M., Hunt J., Zakai D., Aladeojebi A., Ali M., Gaunt A., Barmayehvar B., Kitchen M., Gowda M., Mansour F., Jarvis M., Halliday E., Lefroy R., Nanjaiah P., Lin D.J., Rajgor A.D., Scurrah R.J., Kang C., Watson L.J., Harris G., Royle T., Cunningham Y., Steel B., Luk A.C.O., Boulton A.J., Bakolas G., Herrod P., Gemmill E., Boyd-Carson H., Jibreel M., Lenzi E., Saafan T., Sapre D., Li Z., Parkins K., Spencer N., Harries R., Egan R.J., Motter D., Jenvey C., Mahoney R., Fine N., Minto T., Henry A., Hollyman M., Grieco C., Gemmell C., Whitmore H., Babar M.S., Goodrum S., Scott R., Collard B., Lau K., Thomas E., Patel A., Allison J., Bowen J., Dias A., Mahendran B., Gopalswamy S., Patil S., Scott L., Sarveswaran J., Michel M., Ravindran S., Subba K., Abou-Foul A.K., Khalefa M., Hossain F., Moores T., Pickering L., Stables G., Doorgakant A., Thiruvasagam V.G., Carter J., Reid S., Mohammed R., Marlow W., Ferguson H., Wilkin R., Konstantinou C., Yershov D., Vatish J., Denning A., Shah H.B., Cross G.W.V., Seyed-Safi P., Smart Y.W., Kuc A., Al-Yaseen M., Olivier J., Hanna M., Eskander P., Duncan R., Halaseh S., Das R., Wynn Jones H., Divecha H., Whelton C., Board T., Powell S., Magee C., Agarwal K., Mangos E., Nambirajan T., Vidya R., Chauhan G., Kaur J., Burahee A., Bleibleh S., Pigadas N., Snee D., Bhasin S., Crichton A., Habeebullah A., Bodla A.S., Yassin N., Mondragon M., Dewan V., Flindall I., Mahendran V., Hanson A., Jenner E., Richards J., Thomas-Fernandez K., Wall R., Alqallaf A., Ben-Sassi A., Mellor K., Joshi P., Joshi Y., Young R., Miu V., Sheridan K., MacDonald L., Green S., Onos L., Wong J.J., Napolitano L., Hemmila M., Amin D., Abramowicz S., Roser S.M., Olson K.A., Riley C., Heron C., Cardenas T., Leede E., Thornhill M., Haynes A.B., McElhinney K., Roward S., Trust M.D., Hill C.E., Teixeira P.G., Etchill E., Stevens K., Ladd M.R., Long C., Rose J., Kent A., Yesantharao P., Vervoort D., Jenny H., Gabre-Kidan A., Margalit A., Tsai L., Malapati H., Yesantharao L., Abdou H., Diaz J., Richmond M., Clark J., O'Meara L., Hanna N., Ying Y., Fleming J., Ovaitt A., Gigliotti J., Fuson A., Cooper Z., Salim A., Hirji S.A., Chung C., Hansen L., Okafor B.U., Roxo V., Raut C.P., Jolissaint J.S., Mahvi D.A., Bankhead-Kendall B., Velmahos G., Maurer L.R., El Moheb M., Gaitanidis A., Naar L., Christensen M.A., Kapoen C., Langeveld K., El Hechi M., Mokhtari A., Haqqani M.H., Drake F.T., Goldenberg-Sandau A., Galbreath B., Reinke C., Ross S., Thompson K., Manning D., Perkins R., Eriksson E., Evans H., Masrur M., Giulianotti P., Benedetti E., Chang G., Ourieff J., Dehart D., Dorafshar A., Price T., Bhama A.R., Torquati A., Cherullo E., Kennedy R., Myers J., Rubin K., Ban V.S., Aoun S.G., Batjer H.H., Caruso J., Carmichael H., Velopulos C.G., Wright F.L., Urban S., McIntyre R.C., Schroeppel T.J., Hennessy E.A., Dunn J., Zier L., Burlew C., Coleman J., Colling K.P., Hall B., Rice H.E., Hwang E.S., Olson S.A., Moris D., Verma R., Hassan R., Volpe A., Merola S., O'Banion L.A., Lilienstein J., Dirks R., Marwan H., Almasri M., Kulkarni G., Mehdi M., Abouassi A., Abdallah M., San Andres M., Eid J., Aigbivbalu E., Sundaresan J., George B., Ssentongo A., Ssentongo P., Oh J.S., Hazelton J., Maines J., Gusani N., Garner M., Horvath S., Zheng F., Ujiki M., Kinnaman G., Meagher A., Sharma I., Holler E., McKenzie K., Chan J., Fretwell K., Nugent W., Khalil A., Chen D., Post N., Rostkowski T., Brahmbhatt D., Huynh K., Hibbard M.L., Schellenberg M., Martin R.C.G., Bhutiani N., Giorgakis E., Laryea J., Bhavaraju A., Sexton K., Kost M., Kimbrough M., Burdine L., Kalkwarf K., Robertson R., Gosain A., Camp L., Lewit R., Kronenfeld J.P., Urrechaga E., Goel N., Rattan R., Hart V., Gilna G., Cioci A., Ruiz G., Rakoczy K., Pavlis W., Saberi R., Morris R., Karam B.S., Brathwaite C.E.M., Liu H., Petrone P., Hakmi H., Sohail A.H., Baltazar G., Heckburn R., Nygaard R.M., Colonna E.T., Endorf F.W., Hill M.J., Maiga A., Dennis B., Levin J.H., Lallemand M., Choron R., Peck G., Soliman F., Rehman S., Glass N., Juthani B., Deisher D., Ruzgar N.M., Ullrich S.J., Sion M., Paranjape C., Kar A.R., Gillezeau C., Rapp J., Taioli E., Miles B.A., Alpert N., Podolsky D., Coleman N.L., Callahan M.P., Brown L., Monson J.R.T., Dehal A., Abbas A., Soliman A., Kim B., Jones C Dauer M.D.E., Renza-Stingone E., Hernandez E., Gokcen E., Kropf E., Sufrin H., Hirsch H., Ross H., Engel J., Sewards J., Poggio J., Sanserino K., Rae L., Philp M., Metro M., McNelis P., Petrov R., Pazionis T., Till B., Lamm R., Rios-Diaz A.J., Palazzo F., Rosengart M., Nicholson K., Carrick M.M., Rodkey K., Suri A., Callcut R., Nicholson S., Talathoti N., Klaristenfeld D., Biffl W., Marsh C., Schaffer K., Berndtson A.E., Averbach S., Curry T., Kwan-Feinberg R., Consorti E., Gonzalez R., Grolman R., Liu T., Merzlikin O., Abel M.K., Ozgediz D., Boeck M., Kornblith L.Z., Nunez-Garcia B., Robinson B., Park P., Utria A.F., Rice-Townsend S.E., Javid P., Hauptman J., Kieran K., Nehra D., Walters A., Cuschieri J., Davidson G.H., Cosker R., Eckhouse S., Choudhry A., Marx W., Jamil T., Seegert S., Al-Embideen S., Quintana M., Jackson H., Wexner S.D., Kent I., Martins P.N., Alshehari M., Al-Naggar H., Alsayadi M., Alyazidi M., Shream S., Alhaddad W., Maqus A., Abu Hamra'a M., Alsayadi R., Ghannam R., Al-Maqtari S., Masdoos S., Al-Harazi Y., Bajjah H., Al-ameri S., Aldawbali M., Gwini G.P., Collaborative, Cardiothoracic Interdisciplinary Research Network and COVIDSurg, Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), The Cardiothoracic Interdisciplinary Research Network and COVIDSurg Collaborative, Akowuah, E, Benson, R, Caruana, E, Chetty, G, Edwards, J, Forlani, S, Gradinariu, G, Murphy, G, Oo, A, Patel, A, Ridley, B, Rogers, L, Sanders, J, Tyson, N, Vaja, R, Siaw-Acheampong, K, Argus, L, Chaudhry, D, Dawson, B, Glasbey, J, Gujjuri, R, Jones, C, Kamarajah, S, Khatri, C, Keatley, J, Lawday, S, Li, E, Mann, H, Marson, E, Mclean, K, Picciochi, M, Taylor, E, Tiwari, A, Simoes, J, Trout, I, Venn, M, Wilkin, R, Bhangu, A, Nepogodiev, D, Dajti, I, Gjata, A, Boccalatte, L, Modolo, M, Cox, D, Pockney, P, Townend, P, Aigner, F, Kronberger, I, Hossain, K, Vanramshorst, G, Lawani, I, Ataide, G, Baiocchi, G, Buarque, I, Gohar, M, Slavchev, M, Agarwal, A, Brar, A, Martin, J, Olivos, M, Calvache, J, Perez Rivera, C, Hadzibegovic, A, Kopjar, T, Mihanovic, J, Klat, J, Novysedlak, R, Christensen, P, El-Hussuna, A, Batista, S, Lincango, E, Emile, S, Mengesha, M, Hailu, D, Tamiru, H, Kauppila, J, Laukkarinen, J, Arnaud, A, Albertsmeiers, M, Lederhuber, H, Loffler, M, Tabiri, S, Metallidis, S, Tsoulfas, G, Lorena, M, Grecinos, G, Mersich, T, Wettstein, D, Ghosh, D, Kembuan, G, Brouk, P, Khosravi, M, Mozafari, M, Adil, A, Mohan, H, Zmora, O, Fiore, M, Gallo, G, Pata, F, Pellino, G, Satoi, S, Ayasra, F, Chaar, M, Fakhradiyev, I, Jamal, M, Elhadi, M, Gulla, A, Roslani, A, Martinez, L, Ramos De La Medina, A, Outani, O, Jonker, P, Kruijff, S, Noltes, M, Steinkamp, P, van der Plas, W, Ademuyiwa, A, Osinaike, B, Seyi-olajide, J, Williams, E, Pejkova, S, Augestad, K, Soreide, K, Al Balushi, Z, Qureshi, A, Sayyed, R, Mohsen Daraghmeh, M, Abukhalaf, S, Cukier, M, Gomez, H, Shu, S, Vasquez, X, Parreno-Sacdalan, M, Major, P, Azevedo, J, Cunha, M, Santos, I, Zarour, A, Bonci, E, Negoi, I, Efetov, S, Litvin, A, Ntirenganya, F, Alameer, E, Radenkovic, D, Hong Xiang, F, Hoe, C, Chi Yong, J, Moore, R, Nhlabathi, N, Colino, R, Bravo, A, Minaya-Bravo, A, Jayarajah, U, Wickramasinghe, D, Elmujtaba, M, Jebril, W, Rutegard, M, Sund, M, Isik, A, Leventoglu, S, Abbott, T, Caruna, E, Chakrabortee, S, Demetriades, A, Desai, A, Drake, T, Evans, J, Ford, S, Fotopoulou, C, Griffiths, E, Hutchinson, P, Jenkinson, M, Khan, T, Knight, S, Kolias, A, Leung, E, Mckay, S, Norman, L, Ots, R, Raghavan, V, Roberts, K, Schache, A, Shaw, R, Shaw, K, Smart, N, Stewart, G, Sundar, S, Vimalchandran, D, Wright, N, Alshryda, S, Alser, O, Breen, K, Ganly, I, Kaafarani, H, Kendall, B, Mashbari, H, Al Naggar, H, Mazingi, D, Valenzuela, J, Gemelli, N, Smith, D, Dudi-Venkata, N, Kroon, H, Sammour, T, Roberts, M, Mitchell, D, Lah, K, Pearce, A, Morton, A, Dawson, A, Drane, A, Sharpin, C, Nataraja, R, Pacilli, M, Muralidharan, V, Riddiough, G, Clarke, E, Jamel, W, Qin, K, Cope, D, Egoroff, N, Lott, N, Putnis, S, De Robles, S, Ang, Z, Mitteregger, M, Uranitsch, S, Stiegler, M, Seitinger, G, Lumenta, D, Nischwitz, S, Richtig, E, Pau, M, Srekl-Filzmaier, P, Eibinger, N, Michelitsch, B, Fediuk, M, Papinutti, A, Seidel, G, Kahn, J, Cohnert, T, Messner, F, Ofner, D, Presl, J, Varga, M, Weitzendorfer, M, Emmanuel, K, Binder, A, Zimmermann, M, Holawe, S, Nkenke, E, Grimm, C, Kranawetter, M, Rahman Mitul, A, Islam, N, Karim, S, Komen, N, Ang, E, De Praetere, H, Tollens, T, Schols, G, Smets, C, Haenen, L, Quintens, J, Van Belle, K, Van Ramshorst, G, Pattyn, P, Desender, L, Martens, T, Van de putte, D, Lerut, P, Grimonprez, A, Janssen, M, De Smul, G, Wallaert, P, Van den Eynde, J, Oosterlinck, W, Van den Eynde, R, Sermon, A, Boeckxstaens, A, Cordonnier, A, De Coster, J, Jaekers, J, Politis, C, Miserez, M, Duchateau, N, De Gheldere, C, Flamey, N, Christiano, A, Guidi, B, Minussi, A, Castro, S, Okoba, W, Maldonado, F, Oliveira, P, Baldasso, T, Santos, L, Gomes, G, Pol-Fachin, L, Bezerra, T, Barros, A, da Silva, A, Leite, A, Silvestre, D, Ferro, C, Araujo, M, Lopes, L, Damasceno, P, Araujo, D, Laporte, G, Salem, M, Guimaraes-Filho, M, Nacif, L, Flumignan, R, Nakano, L, Kuramoto, D, Aidar, A, Pereda, M, Correia, R, Santos, B, Carvalho, A, Amorim, J, Guedes Neto, H, Areias, L, Sousa, A, Flumignan, C, Lustre, W, Moreno, D, Barros, N, Baptista-Silva, J, Matos, L, Kowaski, L, Kulcsar, M, Nunes, K, Teixeira, M, Nunes, R, Ijichi, T, Kim, N, Marreiro, A, Muller, B, Barakat Awada, J, Kowalski, L, Vartanian, J, Makdissi, F, Aguiar, S, Marques, N, Carvalho, G, Marques, T, Abdallah, E, Zurstrassen, C, Gross, J, Zequi, S, Goncalves, B, Santos, S, Duprat, J, Coimbra, F, Cicco, R, Takeda, F, Cecconello, I, Ribeiro, U, Gatti, A, Oliva, R, Nardi, C, Atanasov, B, Belev, N, Dell, A, Bigam, D, Dajani, K, Al Riyami, S, Cheng, D, Yang, H, Fayad, A, Carrier, F, Amzallag, E, Desroches, J, Ruel, M, Caminsky, N, Boutros, M, Moon, J, Wong, E, Vanounou, T, Pelletier, J, Wong, S, Girsowicz, E, Bayne, J, Obrand, D, Gill, H, Steinmetz, O, Mackenzie, K, Lukaszewski, M, Jamjoum, G, Richebe, P, Verdonck, O, Discepola, S, Godin, N, Idrissi, M, Briatico, D, Sharma, S, Talwar, G, Bailey, K, Lecluyse, V, Cote, G, Demyttenaere, S, Garfinkle, R, Kouyoumdjian, A, Dumitra, S, Khwaja, K, Luo, L, Berry, G, Liberman, A, Schmid, S, Spicer, J, Al Farsi, M, Abou-Khalil, J, Couture, E, Mohammadi, S, Tremblay, H, Gagne, N, Bergeron, A, Turgeon, A, Costerousse, O, Bellemare, D, Babin, C, Blier, C, Wood, M, Persad, A, Groot, G, Pham, H, D'Aragon, F, Carbonneau, E, 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A, Rodriguez-Abreu, J, Tactuk, N, Diaz-Delgado, P, Rivas, R, Sarmiento-Bobadilla, J, Ashoush, F, Samir Abdelaal, A, Qatora, M, Elsayed Hewalla, M, Metwalli, M, Atta, R, Abdelmajeed, A, Abosamak, N, Sabry, A, Shehata, S, Sallam, I, Amira, G, Sherief, M, Sherif, A, Salem, H, Hamdy, R, Aboulkassem, H, Ghaly, G, Sherif, G, Morsi, A, Abdelrahman, A, Omnia, A, Tawheed, A, El Kassas, M, Omar, W, Abdelsamed, A, Seleim, A, Azzam, A, Elfiky, M, Nabil, A, Ibraheem, M, Eldeeb, M, Fawzy, M, Hamed, H, Elfallal, A, Elfeki, H, Shalaby, M, Sakr, A, Alrahawy, M, Atif, H, Soltan, H, Sayed, A, Salah, A, Atiya, A, Wassim, K, Abbas, A, Abd Elazeem, H, Abd-Elkariem, A, Abd-Elkarem, M, Alaa, S, Ali, A, Ashraf, M, Ayman, A, Azizeldine, M, Elkhayat, H, Emad Mashhour, A, Gaber, M, Hamza, H, Hawal, I, Hetta, H, Elghazaly, S, Mohammed, M, Monib, F, Nageh, M, Saad, A, Saad, M, Shahine, M, Yousof, E, Youssef, A, Esmail, E, Khalaf, M, Eldaly, A, Ghoneim, A, Hawila, A, Badr, H, Elhalaby, I, Abdel-bari, M, Elbahnasawy, 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Gjata, Arben, Boccalatte, Lui, Modolo, Maria Marta, Cox, Daniel, Pockney, Peter, Townend, Philip, Aigner, Felix, Kronberger, Irmgard, Hossain, Kamral, VanRamshorst, Gabrielle, Lawani, Ismail, Ataide, Gustavo, Baiocchi, Glauco, Buarque, Igor, Gohar, Muhammad, Slavchev, Mihail, Agarwal, Arnav, Brar, Amanpreet, Martin, Janet, Olivos, Maricarmen, Calvache, Jose, Perez Rivera, Carlos Jose, Hadzibegovic, Ana Danic, Kopjar, Tomislav, Mihanovic, Jakov, Klat, Jaroslav, Novysedlak, René, Christensen, Peter, El-Hussuna, Alaa, Batista, Sylvia, Lincango, Eddy, Emile, Sameh H., Mengesha, Mengistu Gebreyohane, Hailu, Dr.Samuel, Tamiru, Hailu, Kauppila, Joona, Laukkarinen, Johanna, Arnaud, Alexi, Albertsmeiers, Marku, Lederhuber, Han, Loffler, Marku, Tabiri, Stephen, Metallidis, Symeon, Tsoulfas, Georgio, Lorena, Maria Aguilera, Grecinos, Gustavo, Mersich, Tama, Wettstein, Daniel, Ghosh, Dhruv, Kembuan, Gabriele, Brouk, Peiman, Khosravi, Mohammad, Mozafari, Masoud, Adil, Ahmed, Mohan, Helen M., Zmora, Oded, Fiore, Marco, Gallo, Gaetano, Pata, Francesco, Pellino, Gianluca, Satoi, Sohei, Ayasra, Fari, Chaar, Mohammad, Fakhradiyev, Ildar R., Jamal, Mohammad, Elhadi, Muhammed, Gulla, Aiste, Roslani, April, Martinez, Laura, Ramos De La Medina, Antonio, Outani, Oumaima, Jonker, Pascal, Kruijff, Schelto, Noltes, Milou, Steinkamp, Pieter, van der Plas, Willemijn, Ademuyiwa, Adesoji, Osinaike, Babatunde, Seyi-olajide, Justina, Williams, Emmanuel, Pejkova, Sofija, Augestad, Knut Magne, Soreide, Kjetil, Al Balushi, Zainab, Qureshi, Ahmad, Sayyed, Raza, Mohsen Daraghmeh, Mustafa Abu, Abukhalaf, Sadi, Cukier, Moise, Gomez, Hugo, Shu, Sebastian, Vasquez, Ximena, Parreno-Sacdalan, Marie Dione, Major, Piotr, Azevedo, José, Cunha, Miguel, Santos, Irene, Zarour, Ahmad, Bonci, Eduard-Alexandru, Negoi, Ionut, Efetov, Sergey, Litvin, Andrey, Ntirenganya, Faustin, AlAmeer, Ehab, Radenkovic, Dejan, Hong Xiang, Frederick Koh, Hoe, Chew Min, Chi Yong, James Ngu, Moore, Rachel, Nhlabathi, Ncamsile, Colino, Ruth Blanco, Bravo, Ana Minaya, Minaya-Bravo, Ana, Jayarajah, Umesh, Wickramasinghe, Dakshitha, Elmujtaba, Mohammed, Jebril, William, Rutegård, Martin, Sund, Malin, Isik, Arda, Leventoğlu, Sezai, Abbott, Tom EF., Benson, Ruth, Caruna, Ed, Chakrabortee, Sohini, Demetriades, Andrea, Desai, Anant, Drake, Thomas D., Edwards, John G., Evans, Jonathan P., Ford, Samuel, Fotopoulou, Christina, Griffiths, Ewen, Hutchinson, Peter, Jenkinson, Michael D., Khan, Tabassum, Knight, Stephen, Kolias, Angelo, Leung, Elaine, McKay, Siobhan, Norman, Lisa, Ots, Riinu, Raghavan, Vidya, Roberts, Keith, Schache, Andrew, Shaw, Richard, Shaw, Katie, Smart, Neil, Stewart, Grant, Sundar, Sudha, Vimalchandran, Dale, Wright, Naomi, Alshryda, Sattar, Alser, Osaid, Breen, Kerry, Ganly, Ian, Kaafarani, Haytham, Kendall, Brittany, Mashbari, Hassan, Al Naggar, Hamza, Mazingi, Denni, Simoes, Joana F.F., Dajti, I., Valenzuela, J.I., Boccalatte, L.A., Gemelli, N.A., Smith, D.E., Dudi-Venkata, N.N., Kroon, H.M., Sammour, T., Roberts, M., Mitchell, D., Lah, K., Pearce, A., Morton, A., Dawson, A.C., Drane, A., Sharpin, C., Nataraja, R.M., Pacilli, M., Cox, D.R.A., Muralidharan, V., Riddiough, G.E., Clarke, E.M., Jamel, W., Qin, K.R., Pockney, P., Cope, D., Egoroff, N., Lott, N., Putnis, S., De Robles, S., Ang, Z., Mitteregger, M., Uranitsch, S., Stiegler, M., Seitinger, G., Aigner, F., Lumenta, D.B., Nischwitz, S.P., Richtig, E., Pau, M., Srekl-Filzmaier, P., Eibinger, N., Michelitsch, B., Fediuk, M., Papinutti, A., Seidel, G., Kahn, J., Cohnert, T.U., Messner, F., Öfner, D., Presl, J., Varga, M., Weitzendorfer, M., Emmanuel, K., Binder, A.D., Zimmermann, M., Holawe, S., Nkenke, E., Grimm, C., Kranawetter, M., Rahman Mitul, A., Islam, N., Karim, S., Komen, N., Ang, E., De Praetere, H., Tollens, T., Schols, G., Smets, C., Haenen, L., Quintens, J., Van Belle, K., Van Ramshorst, G.H., Pattyn, P., Desender, L., Martens, T., Van de putte, D., Lerut, P., Grimonprez, A., Janssen, M., De Smul, G., Wallaert, P., 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Awada, J., Baiocchi, G., Kowalski, L.P., Vartanian, J.G., Makdissi, F.B., Aguiar, S., Marques, N., Carvalho, G.B., Marques, T.M.D.M., Abdallah, E.A., Zurstrassen, C.E., Gross, J.L., Zequi, S.C., Gonçalves, B.T., Santos, S.S., Duprat, J.P., Coimbra, F.J.F., Cicco, R., Takeda, F., Cecconello, I., Ribeiro, U., Gatti, A., Oliva, R., Nardi, C., Slavchev, M., Atanasov, B., Belev, N., Dell, A., Bigam, D., Dajani, K., Al Riyami, S., Martin, J., Cheng, D., Yang, H., Fayad, A., Carrier, F.M., Amzallag, E., Desroches, J., Ruel, M., Caminsky, N.G., Boutros, M., Moon, J., Wong, E.G., Vanounou, T., Pelletier, J., Wong, S., Girsowicz, E., Bayne, J., Obrand, D., Gill, H., Steinmetz, O., MacKenzie, K., Lukaszewski, M., Jamjoum, G., Richebé, P., Verdonck, O., Discepola, S., Godin, N., Idrissi, M., Briatico, D., Sharma, S., Talwar, G., Bailey, K., Lecluyse, V., Côté, G., Demyttenaere, S., Garfinkle, R., Kouyoumdjian, A., Dumitra, S., Khwaja, K., Luo, L., Berry, G., Liberman, A.S., Schmid, S., Spicer, J., Al Farsi, M., Abou-Khalil, J., Couture, E., Mohammadi, S., Tremblay, H., Gagné, N., Bergeron, A., Turgeon, Af, Costerousse, O., Bellemare, D., Babin, C., Blier, C., Wood, M.L., Persad, A., Groot, G., Pham, H., D'Aragon, F., Carbonneau, E., Bouchard, M., Masse, M., Pesant, F., Héroux, J., Karanicolas, P., Hallet, J., Nadler, A., Nathens, A., Ko, M., Brar, A., Mayson, K., Kidane, B., Srinathan, S., Escudero, M.I., Reyes, J.T., Modolo, M.M., Ramirez Nieto, P., Sepulveda, R., Bolbarán, A., Molero, A., Ruiz, I., Reyes, G.P., Salas, R., Suazo, C., Muñoz, R., Grasset, E., Inzunza, M., Besser, N., Irarrázaval, M.J., Jarry, C., Bellolio, F., Romero Manqui, C.A., Ruiz Esquide, M., Fuentes, T., Campos, J., Perez Rivera, C.J., Cabrera, P.A., Pinilla, R.E., Guevara, O., Jimenez Ramirez, L.J., Velasquez Cuasquen, B.G., Herrera Mora, D.R., Bonilla, A., Diaz, S., Manrique, E., Facundo, H., Velez Bernal, J.L., Ángel, J., García, M., Guzmán, L., Lehmann, C., Cervera, S., Trujillo Sanchez, L.M., Guevara, R., Valbuena, D., Suarez, L., Jimenez, G., Velandia, A., Vargas, J., Espinosa, J., Rey, S., Mendoza Quevedo, Jairo, Calvache, J.A., Orozco-Chamorro, C.M., Sánchez-Gómez, T.A., Rojas-Tejada, D.A., Mihanovic, J., Bakmaz, B., Rakvin, I., Sulen, N., Andabaka, T., Luksic, I., Mamic, M., Martinek, L., Skrovina, M., Žatecký, J., Peteja, M., Kristensen, H.Ø., Mekhael, M., Christensen, P., Westh, L., Smith, H., Haugstvedt, A.F., Jönsson, M.L., Crespo, A., Batista, S., Rodriguez-Abreu, J., Tactuk, N., Diaz-Delgado, P.J., Rivas, R., Sarmiento-Bobadilla, J.A., Ashoush, F., Samir Abdelaal, A., Qatora, M.S., Elsayed Hewalla, M.E., Metwalli, M., Atta, R., Abdelmajeed, A., Abosamak, N.E., Sabry, A., Shehata, S., Sallam, I., Amira, G., Sherief, M., Sherif, A., Salem, H., Hamdy, R., Aboulkassem, H., Ghaly, G., Sherif, G., Morsi, A., Abdelrahman, A., Omnia, Ahmed, Tawheed, A., El Kassas, M., Omar, W., Abdelsamed, A., Seleim, A., Azzam, A.Y., ElFiky, M., Nabil, A., Ibraheem, M., ELDeeb, M., Fawzy, M., Hamed, H., Emile, S., Elfallal, A., Elfeki, H., Shalaby, M., Sakr, A., Alrahawy, M., Atif, H., Soltan, H., Sayed, A.K., Salah, A., Atiya, A., Wassim, K., Abbas, A.M., Abd Elazeem, H.A.S., Abd-Elkariem, A.Y., Abd-Elkarem, M.M., Alaa, S., Ali, A.K., Ashraf, M., Ayman, A., Azizeldine, M.G., Elkhayat, H., Emad Mashhour, A., Gaber, M., Hamza, H.M., Hawal, I., Hetta, H.F., Elghazaly, S.M., Mohammed, M.M., Monib, F.A., Nageh, M.A., Saad, A., Saad, M.M., Shahine, M., Yousof, E.A., Youssef, A., Esmail, E., Khalaf, M., Eldaly, A., Ghoneim, A., Hawila, A., Badr, H., Elhalaby, I., Abdel-bari, M., Elbahnasawy, M., Hamada, M.K., Morsy, M.S., Hammad, M., Essa, M., Fayed, M.T., Elzoghby, M., Rady, M., Hamad, O., Salman, S., Sarsik, S., Abd-elsalam, S., Gamal Badr, S., El-Masry, Y., Moahmmed, M.M.H., Hailu, S., Wolde, A., Mengesha, M., Nida, S., Workneh, M., Y Ahmed, M., Fisseha, T., Kassa, D., Zeleke, H., Admasu, A., Laeke, T., Tirsit, A., Gessesse, M., Addissie, A., Bekele, D., Kauppila, J.H., Sarjanoja, E., Testelin, S., Dakpé, S., Devauchelle, B., Bettoni, J., Lavagen, N., Schmitt, F., Lemée, J.M., Boucher, S., Breheret, R., Kün-Darbois, J.D., Kahn, A., Gueutier, A., Bigot, P., Borraccino, B., Lakkis, Z., Doussot, A., Heyd, B., Manfredelli, S., Mathieu, P., Paquette, B., Turco, C., Barrabe, A., Louvrier, A., Moszkowicz, D., Giovinazzo, D., Bretagnol, F., Police, A., Charre, L., Volpin, E., Braham, H., El Arbi, N., Villefranque, V., Bendjemar, L., Girard, E., Abba, J., Trilling, B., Chebaro, A., Lecolle, K., Truant, S., El Amrani, M., Zerbib, P., Pruvot, F.R., Mathieu, D., Surmei, E., Mattei, L., Marin, H., Christou, N., Ballouhey, Q., Ferrero, P., Coste Mazeau, P., Tricard, J., Barrat, B., Taibi, A., Usseglio, J., Laloze, J., Salle, H., Fourcade, L., Duchalais, E., Regenet, N., Rigaud, J., Waast, D., Denis, W., Malard, O., Buffenoir, K., Espitalier, F., Ferron, C., Varenne, Y., Crenn, V., De Vergie, S., Cristini, J., Samarut, E., Tzedakis, S., Bouche, P.A., Gaujoux, S., Kantor, E., Gossot, D., Seguin-Givelet, A., Fuks, D., Grigoroiu, M., Sanchez Salas, R., Cathelineau, X., Macek, P., Barbé, Y., Rozet, F., Barret, E., Mombet, A., Cathala, N., Brian, E., Zadegan, F., Conso, C., Blanc, T., Broch, A., Sarnacki, S., Ali, L., Bonnard, A., Peycelon, M., Hervieux, E., Clermidi, P., Maisonneuve, E., Aubry, E., Thomin, A., Langlais, T., Passot, G., Glehen, O., Cotte, E., Lifante, J.C., De Simone, B., Chouillard, E., Arnaud, A.P., Violas, P., Bergeat, D., Merdrignac, A., Scalabre, A., Perotto, L.O., Le Roy, B., Haddad, E., Vermersch, S., Ezanno, A.C., Barbier, O., Vigouroux, F., Malgras, B., Aime, A., Seeliger, B., Mutter, D., Philouze, G., Pessaux, P., Germain, A., Chanty, H., Ayav, A., Kassir, R., Von theobald, P., Sauvat, F., O'Connor, J., Mayombo Idiata, M., O'Connor, Z., Tchoba, S., Modabber, A., Winnand, P., Hölzle, F., Sommer, B., Shiban, E., Wolf, S., Anthuber, M., Sommer, F., Kaemmerer, D., Schreiber, T., Kamphues, C., Lauscher, J.C., Schineis, C., Loch, F.N., Beyer, K., Nasser, S., Sehouli, J., Höhn, P., Braumann, C., Reinkemeier, F., Uhl, W., Weitz, J., Bork, U., Welsch, T., Praetorius, C., Korn, S., Distler, M., Fluegen, G., Knoefel, W.T., Vay, C., Golcher, H., Grützmann, R., Binder, J., Meister, P., Gallinat, A., Paul, A., Schnitzbauer, A.A., Thoenissen, P., El Youzouri, H., Schreckenbach, T., Nguyen, T.A., Eberbach, H., Bayer, J., Erdle, B., Sandkamp, R., Nitschke, C., Izbicki, J., Uzunoglu, F.G., Koenig, D., Gosau, M., Böttcher, A., Heuer, A., Klatte, T.O., Priemel, M., Betz, C.S., Burg, S., Möckelmann, N., Busch, C.J., Bewarder, J., Zeller, N., Smeets, R., Thole, S., Vollkommer, T., Speth, U., Stangenberg, M., Hakami, I., Boeker, C., Mall, J., Schardey, H.M., von Ahnen, T., von Ahnen, M., Brunner, U., Tapking, C., Kneser, U., Hirche, C., Jung, M., Kowalewski, K.F., Kienle, P., Reissfelder, C., Seyfried, S., Herrle, F., Hardt, J., Galata, C., Birgin, E., Rahbari, N., Vassos, N., Stoleriu, M.G., Hatz, R., Albertsmeier, M., 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M., Clarizia, G., Grechi, A., Longhini, A., Guaitoli, E., Manca, G., Grossi, U., Novello, S., Zanus, G., Romano, M., Rossi, S., Ferrara, F., La Torre, M., Pirozzolo, G., Recordare, A., Paiella, S., Turri, G., Rattizzato, S., Campagnaro, T., Guglielmi, A., Pedrazzani, C., Ruzzenente, A., Poletto, E., Conci, S., Casetti, L., Fontana, M., Salvia, R., Malleo, G., Esposito, A., Landoni, L., De Pastena, M., Bassi, C., Tuveri, M., Nobile, S., Marchegiani, G., Bortolasi, L., Sambugaro, E., Malavolta, M., Moretto, G., Impellizzeri, H., Inama, M., Barugola, G., Ascari, F., Ruffo, G., Granieri, S., Cotsoglou, C., Berselli, M., Desio, M., Marchionini, V., Cocozza, E., Di Saverio, S., Ietto, G., Iovino, D., Carcano, G., Ayasra, F., Qasem, A., Ayasra, Y., Al-Masri, M., Abou Chaar, M.K., Al-Najjar, H., Ghandour, K., Alawneh, F., Abdel Jalil, R., Abdel Al, S., Elayyan, M., Ghanem, R., Lataifeh, I., Alsaraireh, O., Abu Za’nouneh, F.J., Fahmawee, T., Ibrahim, A., Obeidat, K., Lee, K.J., Shin, S.J., 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García, F.C., Melchor-Ruan, J., Vilar-Compte, D., Romero-Bañuelos, E., Herrera-Gomez, A., Meneses-Garcia, A., Isla-Ortiz, D., Salcedo-Hernández, R.A., Hernández-Nava, J.M., Morales-Castelan, J.E., Posadas-Trujillo, O.E., Buerba, G.A., Alfaro-Goldaracena, A., Pena Gomez-Portugal, E., Lopez-Pena, G., Hinojosa, C.A., Mercado, M.A., Ramos-De la Medina, A., Martinez, L., Duran, I., Gonzalez, D.S., Martinez, M.J., Nayen Sainz de la Fuente, A., Miguelena, L., Hernández Miguelena, L., Louraoui, S.M., El Azhari, A., Rghioui, M., Khya, E., Ghannam, A., Souadka, A., El Ahmadi, B., Belkhadir, Z.H., Majbar, M.A., Benkabbou, A., Mohsine, R., Oudrhiri, M.Y., Bechri, H., Arkha, Y., El Ouahabi, A., Frima, H., Bachiri, S., Groen, L.C., Verhagen, T., ter Brugge, F.M., Scheijmans, J.C.G., Boermeester, M.A., Hompes, R., Meima-van Praag, E.M., Sharabiany, S., Borgstein, A.B.J., Gisbertz, S.S., van Berge Henegouwen, M.I., Gans, S., Van Duijvendijk, P., Herklots, T., De Hoop, T., De Graaff, M.R., Sloothaak, 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Rashid, I., Ayubi, A., Bhatti, A.B.H., Younis, M.U., Ghouri, A., Ayub, B., Sayyed, R.H., Saleem, A., Turk, K., Alvi, A., Abassy, J., Khan, S., Arshad, M., Ahmed, K., Siddiqui, T., Pirzada, A., Kerawala, A.A., Jamal, A., Rai, L., Nafees Ahmed, R., Memon, A.S., Qureshi, A.U., Ayyaz, M., Umar, M., Butt, U., Kashif, M., Khan, W.H., Waris Farooka, M., Wasim, T., Talat, N., Tahir, W., Naseem, J., Akbar, A., Afroze, S., Sultan, A., Ali, H.B., Janjua, M.H., Janjua, A., Asghar, S., Farooq, M.S., Sarwar, M.Z., Naqi, S.A., Gondal, K.M., Bukhari, S.I., Tariq, M., Javed, S., Yaqoob, E., Mahmood, U., Raja Shabbir, K., Abukhalaf, S.A., Amro, A., Cabada Lee, J.M., Aguilar, A., Rodriguez, E., Castillo, K., Cukier, M., Rodriguez-Zentner, H., Arrue, E., Isaacs Beron, R., Rodríguez Gonzalez, A., Panduro-Correa, V., Cornelio, D.K., Otiniano Alvarado, C.E., Caballero Sarabia, V.D., Vasquez-Ojeda, X.P., Lizzetti-Mendoza, G., Niquen-Jimenez, M., Shu-Yip, S.B., León Palacios, J.L., Borda-Luque, G., Zegarra, 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Y.W., Kuc, A., Al-Yaseen, M., Olivier, J., Hanna, M., Eskander, P., Duncan, R., Halaseh, S., Das, R., Wynn Jones, H., Divecha, H., Whelton, C., Board, T., Powell, S., Magee, C., Agarwal, K., Mangos, E., Nambirajan, T., Vidya, R., Chauhan, G., Kaur, J., Burahee, A., Bleibleh, S., Pigadas, N., Snee, D., Bhasin, S., Crichton, A., Habeebullah, A., Bodla, A.S., Yassin, N., Mondragon, M., Dewan, V., Flindall, I., Mahendran, V., Hanson, A., Jenner, E., Richards, J., Thomas-Fernandez, K., Wall, R., Alqallaf, A., Ben-Sassi, A., Mellor, K., Joshi, P., Joshi, Y., Young, R., Miu, V., Sheridan, K., MacDonald, L., Green, S., Onos, L., Wong, J.J., Napolitano, L., Hemmila, M., Amin, D., Abramowicz, S., Roser, S.M., Olson, K.A., Riley, C., Heron, C., Cardenas, T., Leede, E., Thornhill, M., Haynes, A.B., McElhinney, K., Roward, S., Trust, M.D., Hill, C.E., Teixeira, P.G., Etchill, E., Stevens, K., Ladd, M.R., Long, C., Rose, J., Kent, A., Yesantharao, P., Vervoort, D., Jenny, H., Gabre-Kidan, A., Margalit, A., Tsai, L., Malapati, H., Yesantharao, L., Abdou, H., Diaz, J., Richmond, M., Clark, J., O'Meara, L., Hanna, N., Ying, Y., Fleming, J., Ovaitt, A., Gigliotti, J., Fuson, A., Cooper, Z., Salim, A., Hirji, S.A., Chung, C., Hansen, L., Okafor, B.U., Roxo, V., Raut, C.P., Jolissaint, J.S., Mahvi, D.A., Kaafarani, H., Breen, K., Bankhead-Kendall, B., Alser, O., Mashbari, H., Velmahos, G., Maurer, L.R., El Moheb, M., Gaitanidis, A., Naar, L., Christensen, M.A., Kapoen, C., Langeveld, K., El Hechi, M., Mokhtari, A., Haqqani, M.H., Drake, F.T., Goldenberg-Sandau, A., Galbreath, B., Reinke, C., Ross, S., Thompson, K., Manning, D., Perkins, R., Eriksson, E., Evans, H., Masrur, M., Giulianotti, P., Benedetti, E., Chang, G., Ourieff, J., Dehart, D., Dorafshar, A., Price, T., Bhama, A.R., Torquati, A., Cherullo, E., Kennedy, R., Myers, J., Rubin, K., Ban, V.S., Aoun, S.G., Batjer, H.H., Caruso, J., Carmichael, H., Velopulos, C.G., Wright, F.L., Urban, S., McIntyre, R.C., Schroeppel, 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Rakoczy, K., Pavlis, W., Saberi, R., Morris, R., Karam, B.S., Brathwaite, C.E.M., Liu, H., Petrone, P., Hakmi, H., Sohail, A.H., Baltazar, G., Heckburn, R., Nygaard, R.M., Colonna, E.T., Endorf, F.W., Hill, M.J., Maiga, A., Dennis, B., Levin, J.H., Lallemand, M., Choron, R., Peck, G., Soliman, F., Rehman, S., Glass, N., Juthani, B., Deisher, D., Ruzgar, N.M., Ullrich, S.J., Sion, M., Paranjape, C., Kar, A.R., Gillezeau, C., Rapp, J., Taioli, E., Miles, B.A., Alpert, N., Podolsky, D., Coleman, N.L., Callahan, M.P., Ganly, I., Brown, L., Monson, J.R.T., Dehal, A., Abbas, A., Soliman, A., Kim, B., Jones C Dauer, M.D.E., Renza-Stingone, E., Hernandez, E., Gokcen, E., Kropf, E., Sufrin, H., Hirsch, H., Ross, H., Engel, J., Sewards, J., Poggio, J., Sanserino, K., Rae, L., Philp, M., Metro, M., McNelis, P., Petrov, R., Pazionis, T., Till, B., Lamm, R., Rios-Diaz, A.J., Palazzo, F., Rosengart, M., Nicholson, K., Carrick, M.M., Rodkey, K., Suri, A., Callcut, R., Nicholson, S., Talathoti, N., 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Subjects
Pulmonary and Respiratory Medicine, Male, 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), complication, Article, NO, Cohort Studies, outcomes, complications, following cardiac surgery, coronavirus disease 2019, Postoperative Complications, Cardiovascular Diseases, Female, Humans, Middle Aged, SARS-CoV-2, COVID-19, Cardiac Surgical Procedures, Internal medicine, Cardiovascular Disease, medicine, Cardiac Surgical Procedure, In patient, LS7_4, business.industry, Cardiac surgery, outcome, Surgery, Cohort Studie, Cardiology and Cardiovascular Medicine, business, cardiac surgery, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Cohort study, Human
Abstract

The outbreak of severe acute respiratory syndromecoronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide.1 It has had an unprecedented influence on cardiac surgery internationally, resulting in cautious delivery of surgery and restructuring of services.2 Understanding the influence of COVID-19 on patients after cardiac surgery is based on assumptions from other surgical specialties and single-center studies. The COVIDSurg Collaborative conducted a multicenter cohort study, including 1128 patients, across 235 hospitals, from 24 countries demonstrating perioperative COVID-19 infection was associated with an overall mortality of 24% and postoperative pulmonary complications in half of all patients.3 Cardiac surgery arguably represents a higher risk population than general or orthopedic surgery due to the high American Society of Anesthesiologists grades and multiple comorbidities usually seen. We present a subgroup analysis of COVIDSurg data, including patients who underwent cardiac surgery between March 1, 2020, and July 31, 2020, across 13 countries, with a confirmed perioperative (7 days preoperative up to 30 days postoperative) diagnosis of COVID-19 infection. This is presented in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology statement for cohort studies.4 Categorical variables were expressed as frequency and percentages and c2 or Fisher exact test was used to compare categorical variables. Only anonymized data were collected. Patient consent was obtained unless it was waived by local research committees. In the United Kingdom, the study was registered at each site as either a clinical audit or service evaluation and consent was waived. In other countries, local investigators were responsible for contacting research ethics committees to obtain local or national approvals in line with applicable regulations.

Published
2021

36. Safety of hospital discharge before return of bowel function after elective colorectal surgery

Author

J Chapman, S, Blanco-Colino, R, Pérez-Ajates, S, O Anabitarte Bautista, Hodson, J, C Glasbey, J, Pata, F, Pellino, G, Sgrò, A, Soares, A, T van Elst, S Van Straten, Nepogodiev, D, Borakati, A, F Bath, M, H Yasin, I, Mclean, K, Arthur, T, Kovacevic, M, Delibegovic, S, Karamanliev, M, Swamad, M, Žebrák, R, Paramasivam, R, Martensen, A, M Larsen, H, Rädeker, L, E Frey, P, Kechagias, A, Venara, A, Duchalais, E, Ioannidis, A, Pasquali, S, Simioni, A, Farina, V, Podda, M, Lorenzon, L, Schaeff, V, Otto, A, Jakubauskas, M, R van Elst, T, Chu, M, Pvb, Fagan, I Wells, C, A Alagoa João, Juloski, J, Y El Kasmy El Kasmi, Espin-Basany, E, Clerc, D, Ciubotaru, C, Popescu, S, Yanishev, A, Lee, S, B Ozkan, B, A Yagız Sen, K Aktas, M, E Baki, B, Yüksek, B, Kamarajah, S, A Khaw, R, Mills, E, Goodson, R, Thakral, N, D Ablett, A, Adra, M, Kwek, I, M Khan, S, Quinn, P, R Manley, L, Badran, A, Ramjeeawon, A, Campbell, A, L Tan, H, S Rye, D, Rajaraman, N, G Norman, J, Vutipongsatorn, K, Solomou, G, Akhbari, M, Ali, A, Murray, V, M Baker, D, D Brandao, B, Stainer, B, Thavayogan, R, Jones, D, O Onafowokan, O, Gharooni, A, Dabab, N, Carlton-Carew, S, Kungwengwe, G, Gabriel, M, Sewart, E, C Shortland, T, Lawday, S, Pockney, P, Dawson, A, D Brumfitt, C, Stewart, P, B, Ng, K Luong, J, Ivanov, V, Borisova, A, Neykov, V, Kunčarová, K, Kološová, B, Antonova, T, Farkašová, M, L Harbjerg, J, Brandsborg, S, Brinck, S, D Kjaer, M, Mark-Christensen, A, P Unbehaun, K, Dalsgaard, P, D Lycke, K, Lenaoures, P, Brigand, C, Dumange, E, Gout, M, Moehwald, C, Prem, M, Alhalabi, O, Sliwinski, S, Krupp, J, Gablenz, E, Schmitzer, L, Kopp, A, Steinle, J, Gsenger, J, J Pohl, L, Riccardi, M, M Christodoulou, I, Konstantinidis, M, Machairas, N, Zoikas, A, Balalis, D, K Manatakis, D, L Aguilera, M, Marano, L, Fleres, F, Lovisetto, F, Sasia, D, Segalini, E, Pata, G, Lucchi, A, Sagnotta, A, Campagnaro, T, Petrelli, F, Gallo, G, Papandrea, M, Testa, V, Sinibaldi, G, F Di Candido, Colombo, F, Perrone, G, Aresu, S, 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Subjects
operative, Male, postoperative discharge, Postoperative Complications, 0302 clinical medicine, Colostomy, CRITERIA, Prospective Studies, Bowel function, Colectomy, IMAGINE, stoma, intestines, Proctectomy, Ileostomy, digestive, oral, and skin physiology, patient discharge, colorectal surgery, hospital discharge, bowel function, RECOVERY, Middle Aged, adult, colostomy, elective surgical procedures, female, follow-up studies, humans, ileostomy, ileus, male, middle aged, multivariate analysis, patient readmission, patient safety, postoperative complications, prospective studies, recovery of function, colectomy, proctectomy, Patient Discharge, Colorectal surgery, ileus - - discharge - bowel function - elective - colorectal surgery, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Patient Safety, Cohort study, safety, Adult, medicine.medical_specialty, Ileus, Patient Readmission, defecation, 03 medical and health sciences, medicine, Hospital discharge, Humans, colorectal surgery, colorectal resection, Colorectal resection, defecation, postoperative complications, colorectal surgery, intestines, patient discharge, patient readmission, safety, surgical procedures, operative, colorectal resection, ileus, business.industry, Recovery of Function, Odds ratio, medicine.disease, digestive system diseases, surgical procedures, Surgery, Multivariate Analysis, Defecation, business, Follow-Up Studies
Abstract

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system.A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110).Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients.El íleo es frecuente tras la cirugía colorrectal y se asocia con un aumento del riesgo de las complicaciones postoperatorias. Identificar las características de una recuperación normal del tránsito y la idoneidad para el alta hospitalaria es una tarea difícil. Este estudio examinó la seguridad del alta hospitalaria antes del restablecimiento de la función intestinal. MÉTODOS: Se llevó a cabo un estudio de cohortes prospectivo y multicéntrico a través de una red de colaboración internacional. Se incluyeron pacientes adultos sometidos a resección electiva colorrectal entre enero y abril 2018. El objetivo principal fue el reingreso hospitalario durante los 30 primeros días tras la intervención. Se utilizó un análisis de regresión multivariable para evaluar el impacto del momento del alta en función del restablecimiento de la función intestinal. El objetivo secundario fue las complicaciones postoperatorias en los primeros 30 días después de la cirugía, valoradas mediante el sistema de clasificación de Clavien-Dindo.Se incluyeron en el análisis 3.288 pacientes, de los cuales 301 (9,2%) fueron dados de alta antes del restablecimiento de la función intestinal. La mediana de la estancia hospitalaria de los pacientes dados de alta antes y después del restablecimiento de la función intestinal fue 5 (rango intercuartílico: 4-7) y 7 (6-8) días, respectivamente (P 0,001). No hubo diferencias significativas en las tasas de reingreso entre estos grupos (6,6% versus 8,0%; P = 0,499), y este resultado se mantuvo en el análisis multivariable tras el ajuste por diferencias basales (razón de opotunidades, odds ratio, OR 0,90; i.c. del 95% 0,55-1,46, P = 0,659). Las tasas de complicaciones postoperarorias fueron similares en aquellos dados de alta antes o después del restablecimiento de la función intestinal (complicaciones menores: 34,7% versus 39,5%; complicaciones mayores 3,3% versus 3,4%; P = 0,110). CONCLUSIÓN: Dar de alta antes del restablecimiento de la función intestinal tras cirugía colorrectal electiva parece ser seguro en pacientes debidamente seleccionados.

Published
2020

37. Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study

Author

Glasbey J. C., Bibi S., Pata F., Ozkan B. B., Van Straten S., Hodson J., Chapman S. J., Blanco-Colino R., Pellino G., Sgro A., Soares A., van Elst T., Nepogodiev D., Borakati A., Bath M. F., Yasin I. H., Mclean K., Arthur T., Kovacevic M., Delibegovic S., Karamanliev M., Swamad M., Zebrak R., Paramasivam R., Martensen A., Larsen H. M., Radeker L., Frey P. E., Kechagias A., Venara A., Duchalais E., Ioannidis A., Pasquali S., Simioni A., Farina V., Podda M., Lorenzon L., ItSURG I., Schaeff V., Otto A., Jakubauskas M., van Elst T. R., Chu M., Fagan P. V. B., Wells C. I., Alagoa Joao A., Juloski J., Perez-Ajates S., Anabitarte Bautista O., El Kasmy Y., Espin-Basany E., Clerc D., Ciubotaru C., Popescu S., Yanishev A., Lee S., Yagiz Sen A., Aktas M. K., Baki B. E., Yuksek B., Kamarajah S., Khaw R. A., Mills E., Goodson R., Thakral N., Collaborative S., Ablett A. D., Adra M., Kwek I., Khan S. M., Quinn P., Manley L. R., Badran A., Ramjeeawon A., Campbell A., Tan H. L., Rye D. S., Rajaraman N., Norman J. G., Vutipongsatorn K., Solomou G., Akhbari M., Ali A., Murray V., Baker D. M., Brandao B. D., Stainer B., Thavayogan R., Jones D., Onafowokan O. O., Gharooni A., Dabab N., Carlton-Carew S., Kungwengwe G., Gabriel M., Sewart E., Shortland T. C., Lawday S., Pockney P., Dawson A., Brumfitt C. D., Stewart P., Ng B., Luong J. K., Ivanov V., Borisova A., Neykov V., Kuncarova K., Kolosova B., Antonova T., Farkasova M., Harbjerg J. L., Brandsborg S., Brinck S., Kjaer M. D., Mark-Christensen A., Unbehaun K. P., Dalsgaard P., Lycke K. D., LeNaoures P., Brigand C., Dumange E., Gout M., Moehwald C., Prem M., Alhalabi O., Sliwinski S., Krupp J., Gablenz E., Schmitzer L., Kopp A., Steinle J., Gsenger J., Pohl L. J., Riccardi M., Christodoulou I. M., Konstantinidis M., Machairas N., Zoikas A., Balalis D., Manatakis D. K., Aguilera M. L., Marano L., Fleres F., Lovisetto F., Sasia D., Segalini E., Pata G., Lucchi A., Sagnotta A., Campagnaro T., Petrelli F., Gallo G., Papandrea M., Testa V., Sinibaldi G., Di Candido F., Colombo F., Perrone G., Biancafarina A., Canonico G., Pagnanelli M., Curletti G., Bini R., de Manzoni Garberini A., Impellizzeri H., Cillara N., Tutino R., Picciariello A., Coletta D., Savino G., Ferrara F., Tamini N., Talamo G., Parini D., Giamundo P., lo Conte A., Pagano G., Ripetti V., Pesce A., Menduni N., Giudicissi R., Goldin E., Rega D., Belli A., Andriola V., Gordini L., Foppa C., Piccolo G., Birindelli A., Ferrari C., Ballarini Z., Tirelli F., Milone M., De Rosa M., Pipitone Federico N. S., Molteni B., Tilocca P. L., Sancini G., Piozzi G. N., Lauretta A., Poillucci G., Mulas S., Simcikas D., Portelli L., van Wijnbergen J. W. M., Dinger T. L., ten Doesschate S. F. H., van Dalen A. S. H. M., van den Bos D. D., Hansmann M., Medina Feliz J., Kuiper S. Z., Abdulrahman Z., Pruijssers S. R., Farik S., Elliott B. M., Geneta V. P., Wilton S., Kandelaki H., Peng S. L., Campbell S., Lim Y. K., Yassaie S. S., Murray M., Haran C., Tan J., Castro J., Laranjeira A., Catarino S., Neves-Marques C., Correia J. G., Vieira B. N., Quintela A. C., Serra M. L., Maciel J., Cunha M., Aparicio D. J., Neves J., Azevedo J., Romano M., Eiro F., Romano J., Monteiro C., Claro M., Almeida M. R., Peyroteo M., Machado N. D., Capote H., Ferreira M., Sousa X., Devesa H., Cavadas D., Guerreiro I., Costa M., Rosete M., Salman M., English C., Mohammed N., Litvin A., Cuk V. V., Meszarosova K., Jaich R., De Lima H., Brooks S., Marx M., Nshalati Salvation M., Garcia Cardo J., Mora-Guzman I., Sancho Muriel J., de Andres Olabarria U., Muriel P., Jimenez Vinas C., Alconchel F., Esteban Sinovas O., Gomez del Pulgar A., Fairen Oro C., Lopez Otero M., Figueroa Jimenez S., Claramonte Bellmunt O., Martinez Caballero J., Rubio-Perez I., Aguilar-Martinez M. M., Segura-Sampedro J. J., Olmedo Moreno C., Negre Parra D., Estevez Diz A. M., Martin-Balbuena R., Bustamante Recuenco C., Licardie Bolanos R. E., Fernandez P., Diaz Padillo A., Forero-Torres A., Alberdi San Roman I., Salvador Roses H., Merayo Alvarez M., Villarejo Campos P., Lopes Moreira C. C., Uriol Peralta P., Serrano Navidad M., Ripolles-Melchor J., Garcea A., Gomez Facundo H., Troncoso Pereira P., V Perez Guarinos C., Blaser B., Piazza G., Gagliardi B., Serin H., Yurdaor S. S., Arslan E., Kopac O., Uyanik A., Ozmen B. B., Tiftik E., Aksoy B., Yalcinkaya A., Ozoglu F., Kocer M. D., Bilicen G., Cinar E. N., Uslu O., Kaya Y., Demirci K., Wong J., Farhan-Alanie M. M. H., Suresh G., Asif A., Finch B. J., Bhahirathan Y., Herron J., Yi Tew Z., Obukofe R., Russell C., Suchett-Kay I., Netke T., Williams L., Kisiel A., Liu F. Y., Claireaux H., James P., Mondal A., Kalderon R., Nadama H. H., Al-Saraff Z., Tam J. P. H., Powell-Chandler A., Wood F., Gorgievska R., Ragavoodoo A., Thakrar C., Rojoa D., Palmer C., Davidson K., Giacci L., Hale J., Gan F. W., Makin-Taylor R., Hey C. Y., Toh C., Findlay J. M., Griffiths N., Ganesananthan S., Jasionowska S., Poustie M., Wong C., Turner T., Pyc W., Sloper W., Warner C., Coey J., Mason D., Sait S., Kowal M., Owen M., Saiyed A., Ashworth I., Akbari K., Curran M., Martin P., Parker D., Kwok K., Lye C., Ghaly M., Sammour T., Lewis D., Mundasad R., Wilkes A., Ctercteko G., Maslyankov S., Dimov R., Iliev S., Dimitrov D., Marek F., Orhalmi J., Skalicky P., Skalicky T., Chrz K., Christensen P., Worsoe J., Kristensen E. S., Emmertsen K. J., Loeve U. S., Mihaljevic A. L., Herrle F., Konstantinidis K. M., Korkolis D., Karanikas I., Vincenti L., Anania G., Borghi F., Agresta F., Maretto I., Parisi A., Bucci L., De Palma G., Guglielmi A., Cucinotta E., La Torre F., Cianchi F., Guerrieri M., Trompetto M., Persiani R., Micheletto G., Delrio P., Cantafio S., Ronconi M., Bisagni P. A. G., De Prizio M., Franceschi A., Galleano R., Cavallini M., Brescia A., D'Ambra L., Benevento A., Niolu P., Calgaro M., Colangelo E., Grottola T., Altomare D. F., Puleo S., Salamone G., Pietrabissa A., Poggioli G., Erdas E., Ottonello R., Tonini V., Selvaggi F., Sammarco G., Ceccarelli G., De Nisco C., Surgo D., Taglietti L., Ozolins A., Sivins A., Poskus T., Psaila J., Bemelman W. A., Graat L. J., Langenhoff B., Wijnhoven B. P. L., van de Ven A. H. W., Poelman M., Stassen L. P. S., Slooter G., Acherman Y. I. Z., Hoff C., Gerhards M. F., Stommel M. W. J., Hazebroek E. J., van Geloven A. A. W., Schasfoort R. A., van Leeuwen B. L., Tuynman J. B., van Tilburg M. W. A., Boerma E. G., Sharma P., Jenkins B., Bissett I. P., Herd A., Gordon A., Vernon D., Omundsen M., Ly J., Reddy A., Bonnet G., Harmston C., Morales M., Francisco V., Costa S., Manso A., Amorim E., Pereira J., Cardoso J., Ouro S., Caratao M., Nascimento C., Ribeiro da Silva B., Taranu V., Dias R., Mendes J., Allen M., Silva A., Carlos S., Barbosa E., Carneiro C., Ramos L., Lencastre L., Martins R., Silva-Vaz P., Ridgway P. F., McNamara D. A., Cahill R., Hogan A., Larkin J., O'Connell P. R., Negoi I., Abelevich A., Cuk V. M., Vician M., Ede C., Sardiwalla I., Mulira S., Montwedi D., Oyomno M., Sabia D., Portugal Porras V., Vigorita V., Sanz Ortega G., Garcia J., Espi Macias A., Blanco Antona F., Lujan Mompean J. A., Salvans Ruiz S., Villarejo-Campos P., Romero Simo M., Sanchez-Guillen L., Jimenez-Gomez L. M., Sanchez Lopez A., Golda T., Julia Bergkvist D., Nevado C., Noguera Aguilar J. F., cRicardo Felipe B., Septiem J., Rodriguez Sanchez A., Canete-Gomez J., Ruiz Montesinos I., Millan-Scheiding M., Prieto-Nieto I., Frasson M., Garcia Olmo D., Hubner M., Petermann D., Sauvain M. O., Ozben V., Gecim I. E., Disci E., Rencuzogullari A., Kurt A., Bisgin T., Pehlivan M., Isik A., Onur E., Leventoglu S., Haksal M. C., Erturk M. S., Keskin M., Guner A., Tutcu Sahin S., Ozbalci G. S., Pergel A., Albayrak D., Bruce D., Fearnhead N., Arthur J., Harron M., Beattie G., Titu L., Saunders M., Phillips J., Dindyal S., Cresswell B., Gercek Y., Lee J., Linn T., Faulkner G., Lockwood S., Rees J., Charalabopoulos A., Campbell B., Kontovounisios C., Amarnath T., Johnson M., Epanomeritakis E., Vigs S., Nastro P., Gilliam A., Smolarek S., Wilson T., Orbell J., McIntyre R., Agarwal T., Hainsworth P., Patel P., Vijay J., Liu B., Dhruva Rao P., Roxburgh C., Vipond M., Youssef H., Thorn C., Schizas A., Denley S., Bowley D., Das K., Cuming T., Saha A., Chung L., Pitt J., Davis P., Jones O., Taylor M., Bhargava A., Haji A., Watson N., Bloom I., Singh B., Norwood M., Gurjar S., Stylianides N., Mirza S., Evans M., Williams G., Patil P., Hernon J., Finch G., Green S., Chapple K., Fafemi O., Warusavitarne J., Samee A., Carden C., Ong L., Verma K., Joseph A., Rawat N., Pinkney T., Oke O., Glen P., Maxwell-Armstrong C., Oliphant R., Garner J., Moug S. J., Middleton S., Lund J. N., Smart N. J., Osborn G., Moore T., Raymond T., Knowles C. H., Hany T. S., Clarke R., Khera G., Brady R., Sellahewa C., Mason C., Torrance A., Lasithiotakis K., Knight J., Pullybank A., Ainsworth P., Reid F., Ramwell A., Maslekar S., George R., Skull A., Holtham S., Muhammad K., Lal R., Varcada M., Smith F. M., Howlader M., Defriend D., Kirk S., Richards T., Evans C., Borg C. M., Telford K., Sarfraz N., Busby K., Hollingshead J., Speake D., Pawa N., West D., Chadwick M., Komolafe O., Richardson S., Thornton M., Goede A., Osborne C., Bandyopadhyay D., Foong J., Lee Y. J., Liebenberg P., Mijalkov D., Wells A., Bull N., Ajmera A., Warburton T., Morgan S., Mahmoud A., Schachtel M., Mikhail B., Fomin I., Mekaeil B., Taylor N., Stevenson C., Drane A., Pahalawatta U., Lai L. T., Debiasio A., Jun H. J. S., Hengpoonthana R., Mendis D. M., Robb P. M., Lee H. J., Wyche A. A. B., Davis L. T., Chrimes A., Agarwal A., Zhao J., Williams S., Jayalath J. M. S. N., Khor S., Muddasani T., Childs S., Ridgway S., Blefari N. D. A., Tam H., Puchalski N., Ngai C., Mackenzie J., Johnson N., Holmes M., Zuzek R., Saluja T., Gould T., Goh Y. K., Selvaraj T., Beh Y. Z., Dudi-Venkata N. N., Horne D., Borrow J. L., Campbell C., Cousins G., Jackson L., Maheepala K., Zhao S., Holden E., Tutt L., Thompson B., Collins H., Louie F., Buckland B., Smith D., Chong C., Chua T. H., Nayak C., Redmond J., Tan R. R., Gramlick M., Teh J. S., Ng S. Y., Britten-Jones P., Mohd Rosli R., Pham H. D. V., Jegathees T., Coulter-Nile S. M. C. J., Gosselink M. P., Wang Y. L., Maciaszek M., Chrapko P. S., Nair A., Thirugnanasundralingam V., Muir K., Salibasic M., Pavlov V., Paycheva T., Lyulenina E., Kolev N., Nguen D., Mitkov Y., Mitkov E., Vladova P., Dimitrov V., Hussain M., Gabarski A., Ivanov T., Yotsov T., Ilieva I., Akisheva A., Shoshkova M., Nawaz E., Feradova H., Mladenov T., Jozaf V., Klail T., Pos M., Adel A., Sotona O., Bartos M., Amjad T., Maly O., Berec S., Hanusova M., Hurny M., Risko J., Ludvik M., Stercz M., Treskon R., Pospisil M., Hlavacova L., Tomanova D., Chodora S., Houdek O., Novicky R., Sobotkova K., Cha S., Suta Kimle K., Jirankova K., Bujda M., Paclik A., Trap A., Jurgens-Lahnstein J., Storm M., Damgaard I., Olawi F., Ehlern F., Raos M., Kristensen F. P., Bonnerup K., Amiri S., Enevoldsen M., Hojgaard Pedersen J., Jepsen B. N., Hillgaard T. K., Erichsen S. B., Nielsen C. V., Madsen C. P., Bjerke J., Skejo C. D., Aabling R. R., Sorensen J. S., Turunen A., Katunin J., Niskakangas M., Vignaud T., Frey S., Ricolleau C., Chanut F., Magnin J., Seiboldt T., Beck L., Zamzow K., Betge F., Poncelet A., Truant M., Hauschild H., Neugebauer N., Schoning L., CS Simon S., Galata C., Karampinis I., Thawel T., Seckler A. M., Kerem C., Durdevic S., Antonakopoulos F., Mathioulaki A., Chrysoheris P., Athanasopoulos P. G., Kalles V., Spyrou I., Barkolias C., Paspala A., Papaconstantinou D., Spartalis E., Arkadopoulos N., Prodromidou A., Garoufalia Z., Mendez D., Rosales J., Flores M., Garcia M., Garcia A., Noriega Z., Torselli D., Rodriguez J., Lafranceschina S., Artioli E., Giaccari S., Nevoso V., Schimera A., Marino S., Geretto P., Pellegrino L., Borghi B., Marano A., Corino C., Cannata G., Giuffrida M. C., Landra F., Ongaro D., Baronio G., Raimondo S., Casiraghi S., Salvadori R., Finotti E., Ciccioli E., Galgano A., Zuin M., Bettella A., Barina A., Vendramin E., Palano G., Schiavone D., Di Cintio A., Gemini A., Trastulli S., De Luca M., Desiderio J., Gubbiotti F., Cigognini M., Zaffaroni G., Maffioli A., Colombo S., Bondurri A., Sampietro G., Foschi D., Manigrasso M., Danzi M., Amato R., Anastasio L., Mastella F., Basile R., Peltrini R., Marra E., Luglio G., Giglio M., Anoldo P., Vertaldi S., Grimaldi L., Tammaro N., Pedrazzani C., Turri G., Lazzarini E., Conti C., Vulcano I., Bertilone E., Pintabona G., Viscosi F., Cerasari S., Galiffa G., Lapolla P., Del Basso C., Cirillo B., De Toma G., Fazzi K., Bini S., Coratti F., Montanelli P., Grandi S., Nelli T., Ben Khaled N., Cammelli F., Ferrini E., Billo M. E., Marrosu A. G., Scognamillo F., Pala C., Attene F., Carboni L., Ruggiu M. W., Gabbas G., Marziali I., Mazzocato S., Vergari R., Piazzai F., Kubolli I., Aggiusti A., Paolucci A., Ortenzi M., Olivieri M., Belluco C., Antona A. D., Basso S., Morino M., Mistrangelo M., Clerico G., De Santi G., Bitonti M. F., Frattalone M., Fico V., Santullo F., Belia F., Spinelli A., Marco M., Bevilacqua M., Tringali D., Bevilacqua E., Panizzo V., La Manna V., Migliore G., Aversano A., Fares Bucci A., Marino F., Carbone F., Incollingo P., Romano F. M., Zalla T., Baraghini M., Romoli L., Calussi M., Vellei S., Genzano C., Feroci F., Vita M., Barberis A., Serra D., Grassia M., Romelli M., Ruggiero S., Percassi A., Magri Piccinini A., Monti M., Magnoli M., Romano S., Gaetano P., Pilotta F., Baldassarre L., Bonati E., Aresu S., Saba A., Moretto G., Bacchion M., Casaril A., Inama M., Creciun M., Stella M., Gobatti D., Angelini M., Andolfi E., Miranda E., Scricciolo M., Provenza G., Cavallina G., Frezza B., Fontani A., Malatesti R., Pellicano G. A., Anania M., Pulighe F., Cruccu A., Murru M. L., Massaiu C., Balestra F., Pazzona M., Giannella A., Santangelo M., Frangella F., Magagnano D., Liberatore P., Brenna R., Giani A., Tirotta F., Famularo S., Angrisani M., Ceresoli M., Rondelli F., Angelucci G. P., Scaramuzzo R., Larcinese A., Fioriti C., Picone E., Nardi M., Castagnoli G., Bartoli A., Bellochi R., Spaziani A., Conti D., Poponesi V., Trippetti M., Amicucci S., Tazza G., Procacci P., Giovannini F., Basile E., Caristo G., De Nardi P., Rosati R., Marcocci G., Vignali A., Malerba M., Percivale A., Ghazouani O., Reggiani L., Spirito C., Moschetta G., Cosmi F., Romeo G., Gasparrini M., Sucameli F., Gennai A., Moggia E., Bianchi C., Bonfante P., Macina S., Feleppa C., Imperatore M., Tenconi S. M., Rausei S., Maioli D., Marchionini V., Sparta C., Mura F. A., Barmina M., Lorettu A., Rettaroli C., Mastino G., Ruggiu G. V., Mura G. A., Perrone B. A., De Angelis M., Mereu A., Adamo V., Bianco C., Ricciardiello M., Campanaro C., Panaccio P., Esposito L. M., D'Ascanio F., Pietroletti R., Chetta N., Aquilino F., Di Marco F., Amico A., Schembari E., Puglisi S., Licari L., Campanella S., Profita G., Falco N., Rotolo G., Venturelli P., De Marco P., Marciano M., Argenti F., Milani M. S., Malabarba S., Giambartolomei G., Vella I., Gronchi F., Ruggieri A., Roggiani A., Balsamo F., Gori A., Cuicchi D., D'Alessio R., Benvenuto D., Podda F., Cappellacci F., Salaris C., Sanna S., Marcialis J., Mosino L., Peddis M., Melis S., De Donno G., Aru A. C., Falsetti E., Lanari J., D'Errico U., Bianchini S., Figa F., Caiazzo A., Selvaggi L., Capozzolo A., Cerra C., Pirillo M., Cravano S., Libri I., Laquatra N., Isabello A., Truskovs A., Bartnick A., Malcevs E., Machatschek M. J., Alm J., Lapsa S., Delorme M., Zeynalov F., Larnovskis J., Sauka J., Bodrov D., Gailumsis R., Wiemann A. M., Muller N. L., Jelovskis I., Deksnis D., Bauermeister Potts O., Slimbajevs T., Samalavicius N. E., Nutautiene V., Zeromskas P., Jurgaitis J., Aliosin O., Slepavicius A., Eismontas V., Kybransiene M., Dulskas A., Kuliavas J., Kavaliauskas P., Kavaliauskaite R., Poskus E., Danys D., Kryzauskas M., Mikalauskas S., Rackauskas R., Drungilas M., Jotautas V., Strupas K., Cachia C., Cefai C., Youssef Y., Degaetano D., Debono S., Sammut M., Cassar J., Sammut K., Looijen R. C., Becker M. A. J., Comert D., te Molder L., Tromp J., Matthee E., Tissen Y. M., Brinkhuis E., de Vries H. S., 't Hart E., Beckers K., Bekker Y., Kakar S., van Smaalen T. C., Veen O. C., Dingemans S. A., van den Brink L. C., Vijgen G. H. E. J., van de Voort E. M. F., van der Pool A., van Rest K. L. C., Haak T., Sluijpers N. R. F., Molenaar C. J. L., Gordinou de Gouberville M. C., Saleh S., Mens M. A., Hoeks E. M., Nieuwenhuizen S., van Praag E. M., Westerduin E., Smit M. P. C. M., van der Lely S. J., Nasimi B., Gerdsen M., Stijns R. 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J., Navarro Barrios A., Rodriguez Pedreno L., Garcia Moreno P., Garcia Gomez M., Rodrigues K., Platero Diago J., Veras Lista M., Rifa Terricabras S., Butler Sanz L., Alberch Camprubi E., Rico Ferrandez M., Puig Lao E., De Pablo Miro M., Alberca-Paramo A., Alia Verdejo T., Canete-Manzanares J., Molina-Florez M., Garcia Hernandez L. C., Orozco Nunez S., Suarez-Sanchez M., Martin-Fernandez J., Soriano Liebana M. M., Campo Betancourth C. F., Sevila Mico S., Fernandez A., Curtis C., Bosch M., Triguero D., Bosch Ramirez M., Ramayo Diaz N., Gonzalez Caraballo I., Pascual Vicente T., Orue-Echebarria M. I., Sanchez-Calvo L., Wang D., Trueba-Collado C., Morales Bernaldo de Quiros J. T., Lima Pinto F., Nunez OSullivan S., Ramos Jimenez F. A., Perez Ortega A., Trujillo Barbadillo A., Romero Pujana E., Fernandez Illera M. V., De La Llave Serralvo A., Mestres N., Cuello E., Merichal M., Sierra J. E., Escoll J., Rufas M., Pinillos A. I., Ortega J., Vivas Angeles P., Vives Figueras R., Baena Sanfeliu E., Campillo Alonso B., Alberich Prats M., Duran Arrocha J., Cornella Garceso N., Uribe Galeano C., Delisau Puig O., Castro A., Codony Bassols C., Fernandes N., Garcia Adamez J., Caula Freixa C., Sanchez M. J., Martin-Borregon P., Quevedo A., Martinez J., Marin J. M., Rodriguez P., Garcia Orozco J. J., Ferrusola Diaz D. A., Garcia Jimenez M. L., Castro Diez L., Mosquera Fernandez C., Alonso Batanero E., Cifrian Canales I., Calzada M. G., Recuenco C. B., Martin M. C., Esteban Avendano I., Jimenez Relimpio C., Lancho Lavilla P., Blanco Bartolome I., Gomez Cano I., Blasco Andres C., Alonso-Poza A., Dieguez B., Losada M., Gilsanz C., Garcia-Vico A., Roman-Rando A., Sanchez-Galvez M. A., Bersabe-Alonso I. M., Vadillo-Bohorquez A., Gutierrez Rios R. D., Eizaguirre Ubegun M., Novo Sukia I., Uribe Isado M., Ibanez Alda M., Pastor Idoate C., Abad-Motos A., Marinez-Hurtado E., Salvachua-Fernandez R., Padilla Zegarra E. D., Franco M., Martinez A., Ramos Martin P., Mate Mate P., Marcano Chavez C., Ayllon H., Jeri-McFarlane S., Soldevila-Verdeguer C., Pineno-Flores C., Ambrona-Zafra D., Fernandez-Vega L., Gil-Catalan A., Craus-Miguel A., Pujol-Cano N., Sena-Ruiz F., Gomez Jurado M. J., Alberti Delgado P., Bordanova Reverter A., Belzunce-Capo J. F., Verdaguer Tremolosa M., Lin Q., Muniesa C., Avelino L., Cholewa H., Sancho-Muriel J., Navasquillo M., Navio A., Abello D., De Jesus M., Alvarez E., Garcia J. M., Gil A., Giordano H. E., Mignon G., Vanoni A., Henkens A., Jarrar G., Odovic M., Willemin M., Milliet O., Hahnloser D., Demartines N., Teixeira H., Pittet O., Haller M. L., Huot A., Kefleyesus A., Bugmann A., Piotet L. M., Meijers L., Kurtoglu G. K., Sel E. K., Isler V. C., Yilmaz B. S., Adiyaman C., Kara M., Demirkaya H. C., Korkmaz H. K., Pektas A. M., Guner B., Islek E. C., Tombul H. B., Boztug C. Y., Tinaz A., Yilmaz M., Karaman Y., Akin F. A., Dansuk S., Bascavus M., Kaya M., Kutlu B., Seker M. C., Erten V., Memis U., Kocak Z. B., Karapinar Y. E., Fakirullahoglu M., Koseoglu E., Yeni M., Aykun N., Agca M. H., Bilen C., Kilinc I., Atar C., Kilic V., Aktuna C., Aba M., Alim Y. E., Binbuga M., Kurklu O., Ceylan C., Yilmaz S., Calar S. N., Yildirim N., Yavuz G., Can B., Cesmeli E., Kus D., Kavar R. C., Cevlik A. D., Cengiz U., Turk E. G., Yilmaz I., Erdonmez H., Gursoy F., Kara H., Onsal U., Ozbek M., Kasar P. A., Ipor A., Ozen D., Olmez M., Altintas E., Toklu R., Saricicek T., Tipi O. U., Benli G. E., Tasdelen I., Tura A., Ucar A., Ekci B., Bilgili A. C., Kiraz I. N., Aksoy H., Basak A., Erdem M., Kayacan S., Sahin C., Uysal M., Karakus K., Altiner S., Demirci Z. S., Eren E., Yavas M., Aksoy A. B., Karagoz E., Sabanci R., Tumer S. S., Kargici K., Banaz T., Abdulrahman S. M. F., Yesilsancak M., Yanikoglu E., Karabulut A., Yilmaz D., Kuyumcu O. F., Kutluk F., Emiroglu B., Mollavelioglu B., Gereklioglu D., Guler M., Toprak S., Afsar H. B., Guler S. E., Alizade E., Alemdag G., Ulusahin M., Gul E. B., Yildirim R., Semiz A., Bektur G., Tomas K., Yarenci E., Demiroglu Y., Sunal A., Baykan B., Abbasguliyev H., Mutlu V., Mahmoudi Y., Dossa S. A. A., Mizan S. R., Demirtas B., Cavus T., Yuksek A., Mazlum S. S., Yelkenci C., Baran T., Satilmisoglu M., Sahin A. Z., Kilinc A., Isik K., Yumurtaci O., Emin A., Girit C., Yildirak M. K., Senyigit E., Guldag A., Soyleyici B., Aytin Y. E., Akay F. E., Iskan N. G., Mutlu B., Sunay A. O., Tie-Gill T., Ramsay G., De Paola L., McGuckin S., Alshakhs A., Ahmeidat A., Goergen N., Ali Z., Mullarkey L., Walshe R., Lewis E., Berry B., Moneim J., Mookerjee S., Christy S., Ojofeitimi O., Carroll L., Hylands A., Delaugere L. P., Reveendran D., Coulter C., Ralston C., Laverty L., Gallagher P., Ahmed A., Yeo Y. Q., Elliott D., Bennett J., Mcnamara M., Sivarajah S., Dunmore C., Aitken G., Nair M., Aly M. H., Buari M., Ahmed K., Sheikh Z., Monks M., Lehmann J., Rotimi O., Bell T., Limnatitou D., Gormley S., Taleongpong P., Patel V., Macgregor L., Amini S., Turner C., Dwyer-Hemmings L., Busuttil A., Powell J., Hensher C., Vivian F., Wcislo K., Millar Z., Hirosue S., Ogunmwonyi I., Nakakande D., Gaze H., Nirmalanantha A., Bin Amran M. A., Foulkes A., Jones N., Pillai S., Khoury G., Powell T., Maleyko I., Sangheli A., Ransome M., Isse M., Aromolaran O., Bholah H., Anbarasan J., Rehman S., Hu E., Timms S., Reynolds W., Hotchkies A., Misra V., Theocharidou L., Malik T., Janmohamed I., Carhart B., Khan A., Hullait R., Rylance A., Butt S., Leathes J., Philip Rajathasan T., Jeddy H., Kyaw H. A., Wong N., Karelia S., Clements J. M., Rainey M., Joshi N., Rahman A., Gallagher M., Rebuffa N., Abdelgalil R., Siaw Yen Lai R., Laurence N., Thomas S., Green C., Frostick R., Khera R., Povey M., Wong H. 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H., Alawattegama H., Seite E., Barrett A., Riordan E., Lam W., Dowdeswell M., Mulvenna C., Awokoya O., Gurowich L., Dhera K., Hayat S., Tincknell L., Spazzapan M., Teeling F., Sysum K., Latter J., Latter M., Khan S., Guruswamy M., Beedham W., Brazier E., Elghobashy M., Bajaj M., Mann H., Etel E., Woodmass M., Hayden H., Ali Y., Husain S., Arnold A., Pedersen A. C., Cunha P., Ahmed M., Al Zawawi S., Kudva V., Theodoropoulou K., Miscampbell M., Robinson A. V., Johnston J., Dharni A., Lamb S., Westerman T., Evans E., Campbell L., Gillespie M., Cheong C. M., Kulathevanayagam K., Varghese A., Ike S. I., Chu T. S. M., Baljer B., Mogg J. A. W., Rai P., Claireaux H. A., Williams M., Smillie R., Goetz J., Appleby E., Fadipe T., Vaughan-Burleigh S., Puri G., Hussain P., Flather R., Cutler A., Pathak S., Sheldon J., Collicott T., al-Ausi M., Jovaisaite A., Shah S. M., Khalid N., Gutmann D., Davison S., Alame Y. J., Syed L., Owen W. J., Ahsan S. D., Anthony-Uzoeto U., Macleod Hall C., Zheng S., Wynter K., James C., Sapre D., Ghosh R., Baird J., Cockburn L., Blackwood O., Simpson W., Jeong S., Bishop S., Bate R., Hobson C., Adam A. H., Redclift C., Do J., Adeleye O., Poli F., Batterham A., Brown S., Parekh J. N., Clay W., Pieri K., Jackson A., Saxena A., Gurung B., Oyebola T., O'Brien F., Djeugam B., Gardezi S., Ul-Hasan S., Martin-Hernandez M. P., Sisley M., Modi S., Antakia R., Elbayouk A., Soh Y. J., Mather J., Yusuf Z., Al-Sarraf Z., Naja M., Rassool S. B., Convill J., Nikookam Y., Warsame A., Pace C., Kiandee M., Ridwan R., Carey C., Hirri F., McMillan M. J. A., Ling J. J., Pendelbury L., Kerimzade K., Tang A., Howard E. O., Humayun S., Wadsworth O. J., Tan K., Abdelhameed F., Haglund C., Radnaeva I., Hu N., Rambhatla S., Waldron D., Madahar P., Malik S., Meney L. C., Ibrahim I., Kang C. K., Chiu J. Z. J., Livie V., Ibrahim B., Khalil M., Pooley G., Shishkin B., Docherty J., Southgate A., Coomes A., McGee F., Flanagan S., Tan Q. J., Anwar H., Clough R., Chrisp B., Cassels J., Cross G. W. V., Mercer L., Mercer C., Refalo A., Hadley R., McTighe A., Farrow F., Brodie A., Davis G., Shah D. R., Bowers C., Patel S., Morice O., Burzic A., Cheung J., Shashidhara A., Theodoraki G., Birk J., Ong A., Ng M. P. E., Wong R. T. W., Maese S., Yeap B., Iqbal Z., Rojoa D. M., Cabaleiro Barciela C., Ruddy C. M., Lindwe S., Qamar Y., Chuita S., Melaugh T., Hall J. D., Kouli O., Hassane A. S. I., Azhar A. W., Tan T. K., Perchard W., Scurr T., Campbell E., Kelk L., Ghosh A., Gibbins A., Mala D., Loizidou A., Hall O., Mecia L., Hew C., Varathan K., Tong L., Chandrasekar B., Buchanan E., O'Connell M., Kwak S. Y., Ong E. H., Gardner S., Lim J., Maden C., Illahi M., Xuan Tan Z., Stahl R., Stahl J., Hickman A., Collett D., Goolam-Mahomed Z., Allen B., Atiyah A., Ahmad H., Jones J., McGregor O., Ogundiya E., Boulbadaoui A., Kirnon-Jackman O., Lim Q. X., Peckham H., Yeoh T., Yong S. Q., Chen J. Y., Siva S., Sam Z. H., Gilani M., Goh Y. N., Muthukumar M. G., Phillips S., Tjoakarfa J., Giri A., Suresan S., Thomas P., Johnson T. A., Williams R. I., Rashid A., Kushairi A., Rais A., James A., Bugelli M., Chechelnitskaya Y., Sandhu N., Tandon R., Gray M., Kumar A., Ciurleo C., Nyamali I., Hiremath S., Sinha S., Chowdhary M., Bradley E., McTiernan M., Macdonald S., Sharkey S., McLaughlin N., Amey C., Kraria L., Skan O., Kind C., Tupper P., Van Rhee C., Honeyman S. I., Menon G., Jegatheeswaran L., Madhavan A., Warne M., Malcolm F. L., Lessware T., Wilkerson H. T., Chatterjee-Woolman S., Yoong A., Ahmed W. U. R., Longshaw A., Flannery O., Green R., Leaning M., Cragg J., Sharriff H., Doherty C., Kwan K. W. L., Sanders-Crook L., Bhatia S., Eames S., Lewis F., Kirupananthan P., Boh Z. Y., Dass S., Soma A., Newton A., Hill M., Shafiq Y., Brkljac M., Boyce L., English W. J., Lam S., Chipeta C., Jain C., Garofalidou T., Novotny S. A., Locke S., Bowman C., Begaj A., Murphy C., Radcliffe K., Chong J. T., Jeffrey E., Chaudhury N., Rajendran K., Akbar Z., Walters B., Kulendrarajah B., Tran N., Shrestha S., Parmar S., Gallagher C., Hennessy L., Pentti E., Badhrinarayanan S., Fung A., Mansoor M., Kenny R., Kan P., Lee D. E., Khosla S., Samake M., Shaban F., Aftab R., Gough M., Woodburn B., Vayalapra S., McMurrugh K., Jimulia D., Deol S., Pike S., Embury-Young Y., Patel M., Kilgallon E., Keating R., Walsh A., Khan H., Logue G., Orekoya M., Alasmar M., Charalambides M., Clave Llavall A., Williamson E., Bharwada Y., Zearmal S., Evans H., Panikkar M., de la Cruz G., Caplan J., Ruparelia A., Tanvir T., Soare C., Pang Y. L., Trotter J., Zaidi A., Thakrar V., Pulickal P., Ahmed H., Parnell J., Lennock S., Ford V., Brignall R., O'Neill D., Hanna R., Kane R., Nicola M., Rajput K., Xiao Y., Michael S., Wright E., Juniper S., Thompson E., Hoskyns L., Kanitkar A., Ross C., Unsworth A., Rshaidat H., Demarre K., Chiang A., Bareh A., van Dellen J., Faqihinejad C., Gadhvi A., Grant R., Lewsey J., Morris A., Martin H., McClarty C., Sanyal S., Alsaif A., Palkhi A., Bhopal S., Vishnu K S., Papanikolaou A., Mitra A., Nur A., Ali F., Burford C., Huq T., Irwin E., Matthews L., Ngu W. S., Hosfield T., Muneeb F., Page O., Zeb E., Al-Azzawi A., McIntosh J., Vucicevic A., Hughes M., Brooks L., Fanibi B., Dixon M., Njoku P., Morris D., Jobson J., Chowdhury H., Alawode D. O. T., Wynell-Mayow W., Udayachandran V., Alsoof D., Ekert J., Joseph N., Zulkefley N., Hunt G., Christodoulou T., Wright O., Soman S., Jamal M., Beqiri S., Borgas P., Christie S., Pereira F., Browne S., Yiu J., Dworkin A., Brayley J., Palmer A., Charalambos M., Jones C. S., Toner S., Cowden R., Lee L., Nicol P., Holman O., Imtiaz M., Albert V., Leung S. P., Erotocritou M., Stroud R., Wilkin R., Thomson W., Mackee L., G N., Bei Y., Mckenna Favier S., Ibrahim A., Kler A., Reynolds L., Mohamed S. H., Majeed Y., Fakim B., Jones A., Liversedge G., Carrington Z., Windebank J., Izzarina A., Akbani U., Craven J., Aldarragi A., Harding S., Millward A., Bedford M., Gopalan V., Midgen A., Khadka P., Cheng O., Taneja S., Manobharath N., Kok J. Y., Lim D. W. E., Buick T., Boland M., Piya S., Devlin R., Fairfield C. J., George R. J., Rahi M., Zaman S., Hajiev S., Ross T., Crisp E., Thompson C., Charalambous A., Hollywood J. L., Hammond R. F. L., Matthews J., Mendonca V., Spinty J., Khan K., Cheng J., Glynn N., Muhammad U., Khan M., Anderson L., Mccormack K., Mak J., Patrawala S., Milinkovic N., Schofield R., Chauhan M., Hartley L., Hind J., Nelson L., Ratnasingham D., Whitehead T., Dimitriadis S., Marshall K., Flint E. J., Horner C., Heybourne A., Morgan H., Wickstone C., Panagiotou D., O'Connell E., Dean K., Iqbal R., Walsh L., Yu N., Rana N., Massie E., Ng J., Jung M., Lee Y. D., Harris M., White S., Boev B., Tonchev P., Prochazka V., Skalicky A., Ravn S., Ojakaar A., Dorr-Harim C., Koutserimpas C., Giraudo G., Armellini A., Ruzzenente A., Mazzeo C., De Padua C., Realis Luc A., Maroli A., Giani I., Cufari M. E., Vitali M., Gusai G. P., Quattromani R., Virgilio E., Berti S., Di Mola Ospedale SS Annunziata F. F., Papagni V., Tuminello F., Vittori L., Longheu A., Loche G. A., Braccio B., De Luca E., Resta G., Ancans G., Tamosiunas A., Petrulionis M., Andrejevic P., Stellingwerf M. E., Abdulrahman N., van de Pas K. G. H., Thomas G., Brandsma A. M., Davids J., Rottier S. J., de Roy van Zuidewijn D., Hawkins R., Ong H. I., Li Y., Desmond B., Winstanley J., Martins M., Americano M., Frade S., Senhorinho R., Peixoto R., Alves-Vale C., Lamas M., O'Connor D. B., Hoo M., Gopaul A., Scanlon K., O'Dwyer N., Jovanovic M., Panyko A., Van Vuuren S., Centeno A., Bernado I. R., Paniagua Garcia Senorans M., Gonzalez Amor L., Cuenca Ramirez A., Abrisqueta J., Estaire Gomez M., Arroyo A., Cerdan C., Gomez Romeu N., Enriquez-Navascues J. M., Collado-Roura F., Curchod P., Gaspar S., Imadalou L., Mutlu D., Akyol C., Uygur F. A., Eray I. C., Biyiklioglu O., Cetin M. F., Isik A. E., Karip B., Dogan H., Sarigul L., Tunc E., Aydin T., Bodur S., Karabulut K., Francis A. A., Al-hadithi A., To N., Lau I. S. F., Smith E., Mahapatra S., McAuliffe O., Imam L., Akram B., Hossaini S., Davies R., Ko M., Collins J., Pandya A., Reilly S., Archer J., Auty C., Roche C. D., Livie J., Chaudhry F. A., Ntakomyti E., Diallo R., Bylinski T., Wright J., Masiha E., Tung J., Shirazi B., Neilson A., Epton S., Patel N., Trussell S., Couldrey A., Donnelly C., Eftychiou S., Glasbey J.C., Bibi S., Pata F., Ozkan B.B., Van Straten S., Hodson J., Chapman S.J., Blanco-Colino R., Pellino G., Sgro A., Soares A., van Elst T., Nepogodiev D., Borakati A., Bath M.F., Yasin I.H., Mclean K., Arthur T., Kovacevic M., Delibegovic S., Karamanliev M., Swamad M., Zebrak R., Paramasivam R., Martensen A., Larsen H.M., Radeker L., Frey P.E., Kechagias A., Venara A., Duchalais E., Ioannidis A., Pasquali S., Simioni A., Farina V., Podda M., Lorenzon L., ItSURG I., Schaeff V., Otto A., Jakubauskas M., van Elst T.R., Chu M., Fagan P.V.B., Wells C.I., Alagoa Joao A., Juloski J., Perez-Ajates S., Anabitarte Bautista O., El Kasmy Y., Espin-Basany E., Clerc D., Ciubotaru C., Popescu S., Yanishev A., Lee S., Yagiz Sen A., Aktas M.K., Baki B.E., Yuksek B., Kamarajah S., Khaw R.A., Mills E., Goodson R., Thakral N., Collaborative S., Ablett A.D., Adra M., Kwek I., Khan S.M., Quinn P., Manley L.R., Badran A., Ramjeeawon A., Campbell A., Tan H.L., Rye D.S., Rajaraman N., Norman J.G., Vutipongsatorn K., Solomou G., Akhbari M., Ali A., Murray V., Baker D.M., Brandao B.D., Stainer B., Thavayogan R., Jones D., Onafowokan O.O., Gharooni A., Dabab N., Carlton-Carew S., Kungwengwe G., Gabriel M., Sewart E., Shortland T.C., Lawday S., Pockney P., Dawson A., Brumfitt C.D., Stewart P., Ng B., Luong J.K., Ivanov V., Borisova A., Neykov V., Kuncarova K., Kolosova B., Antonova T., Farkasova M., Harbjerg J.L., Brandsborg S., Brinck S., Kjaer M.D., Mark-Christensen A., Unbehaun K.P., Dalsgaard P., Lycke K.D., LeNaoures P., Brigand C., Dumange E., Gout M., Moehwald C., Prem M., Alhalabi O., Sliwinski S., Krupp J., Gablenz E., Schmitzer L., Kopp A., Steinle J., Gsenger J., Pohl L.J., Riccardi M., Christodoulou I.M., Konstantinidis M., Machairas N., Zoikas A., Balalis D., Manatakis D.K., Aguilera M.L., Marano L., Fleres F., Lovisetto F., Sasia D., Segalini E., Pata G., Lucchi A., Sagnotta A., Campagnaro T., Petrelli F., Gallo G., Papandrea M., Testa V., Sinibaldi G., Di Candido F., Colombo F., Perrone G., Biancafarina A., Canonico G., Pagnanelli M., Curletti G., Bini R., de Manzoni Garberini A., Impellizzeri H., Cillara N., Tutino R., Picciariello A., Coletta D., Savino G., Ferrara F., Tamini N., Talamo G., Parini D., Giamundo P., lo Conte A., Pagano G., Ripetti V., Pesce A., Menduni N., Giudicissi R., Goldin E., Rega D., Belli A., Andriola V., Gordini L., Foppa C., Piccolo G., Birindelli A., Ferrari C., Ballarini Z., Tirelli F., Milone M., De Rosa M., Pipitone Federico N.S., Molteni B., Tilocca P.L., Sancini G., Piozzi G.N., Lauretta A., Poillucci G., Mulas S., Simcikas D., Portelli L., van Wijnbergen J.W.M., Dinger T.L., ten Doesschate S.F.H., van Dalen A.S.H.M., van den Bos D.D., Hansmann M., Medina Feliz J., Kuiper S.Z., Abdulrahman Z., Pruijssers S.R., Farik S., Elliott B.M., Geneta V.P., 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Recuenco C., Licardie Bolanos R.E., Fernandez P., Diaz Padillo A., Forero-Torres A., Alberdi San Roman I., Salvador Roses H., Merayo Alvarez M., Villarejo Campos P., Lopes Moreira C.C., Uriol Peralta P., Serrano Navidad M., Ripolles-Melchor J., Garcea A., Gomez Facundo H., Troncoso Pereira P., V Perez Guarinos C., Blaser B., Piazza G., Gagliardi B., Serin H., Yurdaor S.S., Arslan E., Kopac O., Uyanik A., Ozmen B.B., Tiftik E., Aksoy B., Yalcinkaya A., Ozoglu F., Kocer M.D., Bilicen G., Cinar E.N., Uslu O., Kaya Y., Demirci K., Wong J., Farhan-Alanie M.M.H., Suresh G., Asif A., Finch B.J., Bhahirathan Y., Herron J., Yi Tew Z., Obukofe R., Russell C., Suchett-Kay I., Netke T., Williams L., Kisiel A., Liu F.Y., Claireaux H., James P., Mondal A., Kalderon R., Nadama H.H., Al-Saraff Z., Tam J.P.H., Powell-Chandler A., Wood F., Gorgievska R., Ragavoodoo A., Thakrar C., Rojoa D., Palmer C., Davidson K., Giacci L., Hale J., Gan F.W., Makin-Taylor R., Hey C.Y., Toh C., Findlay J.M., Griffiths 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Pietrabissa A., Poggioli G., Erdas E., Ottonello R., Tonini V., Selvaggi F., Sammarco G., Ceccarelli G., De Nisco C., Surgo D., Taglietti L., Ozolins A., Sivins A., Poskus T., Psaila J., Bemelman W.A., Graat L.J., Langenhoff B., Wijnhoven B.P.L., van de Ven A.H.W., Poelman M., Stassen L.P.S., Slooter G., Acherman Y.I.Z., Hoff C., Gerhards M.F., Stommel M.W.J., Hazebroek E.J., van Geloven A.A.W., Schasfoort R.A., van Leeuwen B.L., Tuynman J.B., van Tilburg M.W.A., Boerma E.G., Sharma P., Jenkins B., Bissett I.P., Herd A., Gordon A., Vernon D., Omundsen M., Ly J., Reddy A., Bonnet G., Harmston C., Morales M., Francisco V., Costa S., Manso A., Amorim E., Pereira J., Cardoso J., Ouro S., Caratao M., Nascimento C., Ribeiro da Silva B., Taranu V., Dias R., Mendes J., Allen M., Silva A., Carlos S., Barbosa E., Carneiro C., Ramos L., Lencastre L., Martins R., Silva-Vaz P., Ridgway P.F., McNamara D.A., Cahill R., Hogan A., Larkin J., O'Connell P.R., Negoi I., Abelevich A., Cuk V.M., Vician M., 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C., Amarnath T., Johnson M., Epanomeritakis E., Vigs S., Nastro P., Gilliam A., Smolarek S., Wilson T., Orbell J., McIntyre R., Agarwal T., Hainsworth P., Patel P., Vijay J., Liu B., Dhruva Rao P., Roxburgh C., Vipond M., Youssef H., Thorn C., Schizas A., Denley S., Bowley D., Das K., Cuming T., Saha A., Chung L., Pitt J., Davis P., Jones O., Taylor M., Bhargava A., Haji A., Watson N., Bloom I., Singh B., Norwood M., Gurjar S., Stylianides N., Mirza S., Evans M., Williams G., Patil P., Hernon J., Finch G., Green S., Chapple K., Fafemi O., Warusavitarne J., Samee A., Carden C., Ong L., Verma K., Joseph A., Rawat N., Pinkney T., Oke O., Glen P., Maxwell-Armstrong C., Oliphant R., Garner J., Moug S.J., Middleton S., Lund J.N., Smart N.J., Osborn G., Moore T., Raymond T., Knowles C.H., Hany T.S., Clarke R., Khera G., Brady R., Sellahewa C., Mason C., Torrance A., Lasithiotakis K., Knight J., Pullybank A., Ainsworth P., Reid F., Ramwell A., Maslekar S., George R., Skull A., Holtham S., 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Thompson B., Collins H., Louie F., Buckland B., Smith D., Chong C., Chua T.H., Nayak C., Redmond J., Tan R.R., Gramlick M., Teh J.S., Ng S.Y., Britten-Jones P., Mohd Rosli R., Pham H.D.V., Jegathees T., Coulter-Nile S.M.C.J., Gosselink M.P., Wang Y.L., Maciaszek M., Chrapko P.S., Nair A., Thirugnanasundralingam V., Muir K., Salibasic M., Pavlov V., Paycheva T., Lyulenina E., Kolev N., Nguen D., Mitkov Y., Mitkov E., Vladova P., Dimitrov V., Hussain M., Gabarski A., Ivanov T., Yotsov T., Ilieva I., Akisheva A., Shoshkova M., Nawaz E., Feradova H., Mladenov T., Jozaf V., Klail T., Pos M., Adel A., Sotona O., Bartos M., Amjad T., Maly O., Berec S., Hanusova M., Hurny M., Risko J., Ludvik M., Stercz M., Treskon R., Pospisil M., Hlavacova L., Tomanova D., Chodora S., Houdek O., Novicky R., Sobotkova K., Cha S., Suta Kimle K., Jirankova K., Bujda M., Paclik A., Trap A., Jurgens-Lahnstein J., Storm M., Damgaard I., Olawi F., Ehlern F., Raos M., Kristensen F.P., Bonnerup K., Amiri S., 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E., Ciccioli E., Galgano A., Zuin M., Bettella A., Barina A., Vendramin E., Palano G., Schiavone D., Di Cintio A., Gemini A., Trastulli S., De Luca M., Desiderio J., Gubbiotti F., Cigognini M., Zaffaroni G., Maffioli A., Colombo S., Bondurri A., Sampietro G., Foschi D., Manigrasso M., Danzi M., Amato R., Anastasio L., Mastella F., Basile R., Peltrini R., Marra E., Luglio G., Giglio M., Anoldo P., Vertaldi S., Grimaldi L., Tammaro N., Pedrazzani C., Turri G., Lazzarini E., Conti C., Vulcano I., Bertilone E., Pintabona G., Viscosi F., Cerasari S., Galiffa G., Lapolla P., Del Basso C., Cirillo B., De Toma G., Fazzi K., Bini S., Coratti F., Montanelli P., Grandi S., Nelli T., Ben Khaled N., Cammelli F., Ferrini E., Billo M.E., Marrosu A.G., Scognamillo F., Pala C., Attene F., Carboni L., Ruggiu M.W., Gabbas G., Marziali I., Mazzocato S., Vergari R., Piazzai F., Kubolli I., Aggiusti A., Paolucci A., Ortenzi M., Olivieri M., Belluco C., Antona A.D., Basso S., Morino M., Mistrangelo M., Clerico G., De Santi G., Bitonti M.F., Frattalone M., Fico V., Santullo F., Belia F., Spinelli A., Marco M., Bevilacqua M., Tringali D., Bevilacqua E., Panizzo V., La Manna V., Migliore G., Aversano A., Fares Bucci A., Marino F., Carbone F., Incollingo P., Romano F.M., Zalla T., Baraghini M., Romoli L., Calussi M., Vellei S., Genzano C., Feroci F., Vita M., Barberis A., Serra D., Grassia M., Romelli M., Ruggiero S., Percassi A., Magri Piccinini A., Monti M., Magnoli M., Romano S., Gaetano P., Pilotta F., Baldassarre L., Bonati E., Aresu S., Saba A., Moretto G., Bacchion M., Casaril A., Inama M., Creciun M., Stella M., Gobatti D., Angelini M., Andolfi E., Miranda E., Scricciolo M., Provenza G., Cavallina G., Frezza B., Fontani A., Malatesti R., Pellicano G.A., Anania M., Pulighe F., Cruccu A., Murru M.L., Massaiu C., Balestra F., Pazzona M., Giannella A., Santangelo M., Frangella F., Magagnano D., Liberatore P., Brenna R., Giani A., Tirotta F., Famularo S., Angrisani M., Ceresoli M., 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I., Ortega, J., Vivas Angeles, P., Vives Figueras, R., Baena Sanfeliu, E., Campillo Alonso, B., Alberich Prats, M., Duran Arrocha, J., Cornella Garceso, N., Uribe Galeano, C., Delisau Puig, O., Castro, A., Codony Bassols, C., Fernandes, N., Garcia Adamez, J., Caula Freixa, C., Sanchez, M. J., Martin-Borregon, P., Quevedo, A., Martinez, J., Marin, J. M., Rodriguez, P., Garcia Orozco, J. J., Ferrusola Diaz, D. A., Garcia Jimenez, M. L., Castro Diez, L., Mosquera Fernandez, C., Alonso Batanero, E., Cifrian Canales, I., Calzada, M. G., Recuenco, C. B., Martin, M. C., Esteban Avendano, I., Jimenez Relimpio, C., Lancho Lavilla, P., Blanco Bartolome, I., Gomez Cano, I., Blasco Andres, C., Alonso-Poza, A., Dieguez, B., Losada, M., Gilsanz, C., Garcia-Vico, A., Roman-Rando, A., Sanchez-Galvez, M. A., Bersabe-Alonso, I. M., Vadillo-Bohorquez, A., Gutierrez Rios, R. D., Eizaguirre Ubegun, M., Novo Sukia, I., Uribe Isado, M., Ibanez Alda, M., Pastor Idoate, C., Abad-Motos, A., Marinez-Hurtado, E., Salvachua-Fernandez, R., Padilla Zegarra, E. D., Franco, M., Martinez, A., Ramos Martin, P., Mate Mate, P., Marcano Chavez, C., Ayllon, H., Jeri-McFarlane, S., Soldevila-Verdeguer, C., Pineno-Flores, C., Ambrona-Zafra, D., Fernandez-Vega, L., Gil-Catalan, A., Craus-Miguel, A., Pujol-Cano, N., Sena-Ruiz, F., Gomez Jurado, M. J., Alberti Delgado, P., Bordanova Reverter, A., Belzunce-Capo, J. F., Verdaguer Tremolosa, M., Lin, Q., Muniesa, C., Avelino, L., Cholewa, H., Sancho-Muriel, J., Navasquillo, M., Navio, A., Abello, D., De Jesus, M., Alvarez, E., Garcia, J. M., Gil, A., Giordano, H. E., Mignon, G., Vanoni, A., Henkens, A., Jarrar, G., Odovic, M., Willemin, M., Milliet, O., Hahnloser, D., Demartines, N., Teixeira, H., Pittet, O., Haller, M. L., Huot, A., Kefleyesus, A., Bugmann, A., Piotet, L. M., Meijers, L., Kurtoglu, G. K., Sel, E. K., Isler, V. 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Subjects
medicine.medical_specialty, endocrine system, general surgery, Gastrointestinal, endocrine system diseases, Settore MED/18 - CHIRURGIA GENERALE, pulmonary complications, 03 medical and health sciences, 0302 clinical medicine, Ileus, Nasogastric tube insertion, Medicine, pulmonary complication, pneumonia, EPIDEMIOLOGY, Humans, Prospective Studies, colorectal surgery, nasogastric tube, Prospective cohort study, Intubation, Gastrointestinal, OUTCOMES, VENTILATOR-ASSOCIATED PNEUMONIA, business.industry, Elective Surgical Procedures, Pneumonia, Confounding, Gastroenterology, nutritional and metabolic diseases, Odds ratio, Postoperative pneumonia, medicine.disease, Colorectal surgery, Surgery, body regions, Intubation, Gastrointestinal/adverse effects, Pneumonia/epidemiology, Pneumonia/etiology, Pneumonia/prevention & control, 030220 oncology & carcinogenesis, Vomiting, 030211 gastroenterology & hepatology, medicine.symptom, business, Intubation, hormones, hormone substitutes, and hormone antagonists
Abstract

© 2020 The Association of Coloproctology of Great Britain and IrelandAim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergoing elective colorectal surgery between January 2018 and April 2018 were eligible. Those receiving a NGT were divided into three groups, based on the timing of the insertion: routine NGT (inserted at the time of surgery), prophylactic NGT (inserted after surgery but before vomiting) and reactive NGT (inserted after surgery and after vomiting). The primary outcome was the development of pneumonia within 30 days of surgery, which was compared between the prophylactic and reactive NGT groups using multivariable regression analysis. Results: A total of 4715 patients were included in the analysis and 1536 (32.6%) received a NGT. These were classified as routine in 926 (60.3%), reactive in 461 (30.0%) and prophylactic in 149 (9.7%). Two hundred patients (4.2%) developed pneumonia (no NGT 2.7%; routine NGT 5.2%; reactive NGT 10.6%; prophylactic NGT 11.4%). After adjustment for confounding factors, no significant difference in pneumonia rates was detected between the prophylactic and reactive NGT groups (odds ratio 1.03, 95% CI 0.56–1.87, P = 0.932). Conclusion: In patients who required the insertion of a NGT after surgery, prophylactic insertion was not associated with fewer cases of pneumonia within 30 days of surgery compared with reactive insertion.

Published
2020

38. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Author

Nepogodiev, Dmitri, Bhangu, Aneel, Glasbey, James C, Li, Elizabeth, Omar, Omar M, Simoes, Joana FF, Abbott, Tom EF, Alser, Osaid, Arnaud, Alexis P, Bankhead-Kendall, Brittany K, Breen, Kerry A, Cunha, Miguel F, Davidson, Giana H, Di Saverio, Salomone, Gallo, Gaetano, Griffiths, Ewen A, Gujjuri, Rohan R, Hutchinson, Peter J, Kaafarani, Haytham MA, Lederhuber, Hans, Löffler, Markus W, Mashbari, Hassan N, Minaya-Bravo, Ana, Morton, Dion G, Moszkowicz, David, Pata, Francesco, Tsoulfas, George, Venn, Mary L, Cox, Daniel, Roslani, April C, Alakaloko, Felix, de Vries, Jean-Paul PM, Aaraj, Mahmoud A, Abbott, Sarah J, Abdalla, Mutwakil OM, Abdelaal, Ahmed S, Ademuyiwa, Adesoji O, Aherne, Thomas M, Ali, Osman M, Alkadeeki, Ghadah Z, Almeida, Ana C, Alrahawy, Mahmoud M, Ambler, Graeme K, Alameer, Ehab, Andreani, Stefano M, De Andrés-Asenjo, Beatriz, Antonanzas, Leyre Lopez, Aoun, Salah G, Ashoush, Fouad M, Augestad, Knut Magne, Avellana, Rocio B, Ayeni, Funbi A, Ayorinde, John OO, Babu, Bheemanakone H, Baig, Mirza MAS, Bajomo, Oreoluwa M, Baker, Olivia J, Baker, Markus P, Baldwin, Alexander J, Ban, Vin Shen, Baron, Ryan D, Barranquero, Alberto G, Barry, Conor P, DI Bartolomeo, Alessandro, Bass, Gary A, Bath, Michael F, Batjer, H Hunt, Beamish, Andrew J, Belgaumkar, Ajay P, Bence, Matthew N, Benson, Ruth A, Bernal-Sprekelsen, Juan Carlos, Bhama, Anuradha R, Bhavaraju, Avi V, Biffl, Walter L, Blundell, Chris M, Boddy, Alexander P, Borgstein, Alexander BJ, Bosanquet, David C, Bosch, Karen D, Bouhuwaish, Ahmad EM, Bozkurt, Mehmet A, Brathwaite, Collin EM, Brown, Benjamin C, Brown, Oliver D, Brown, Allison K, Buarque, Igor Lima, Bueno-Cañones, Alejandro D, Bulugma, Mustafa R, Burke, Joshua R, Byrne, Matthew HV, Cagigal-Ortega, Elima P, Callcut, Rachael A, DI Candido, Francesca, Canova, Michaela E, Carlos, William J, Caruana, Edward J, Cato, Liam D, Catton, Andrew B, Ceretti, Andrea Pisani, Chase, Thomas JG, Chiara, Francesco Di, Chowdhury, Abeed H, Chung, Eric A, Cicerchia, Pierfranco M, Clough, Ethan CS, Coleman, Natasha L, Collins, Chris G, Collins, Michelle L, Colonna, Emily T, Comini, Lara V, Coughlin, Patrick A, Cruzado, Laura Fernández-Gomez, Davidson, Brian R, Davies, Richard J, Davies, Emma J, Davis, Niall F, Dawson, Brett E, Dean, Benjamin JF, Delgado, Maria Garcia-Conde, Diaz, Jose J, Dickson, Kathryn E, Diez-Alonso, Manuel M, Dixon, Jan R, Doe, Matthew J, Drake, Thomas D, Drake, Frederick T, Duffy, John P, Dunne, Declan FJ, Dunne, Naomi JM, Durán-Muñoz-Cruzado, Virginia M, Durst, Alexander ZE, Eardley, Nicola J, Edwards, John G, Elfallal, Ahmed H, Elfiky, Mahmoud MA, Elliott, Jessie A, Emile, Sameh H, Emslie, Katy M, Endorf, Frederick W, Engel, Jamie L, Enjuto, Diego T, Etchill, Eric W, Evans, Jonathan P, Fahey, Brian A, Faria, Carlos S, Feo, Carlo V, Ferguson, Henry JM, Fernandez, Beatriz Dieguez, Fernandez, Andres Garcia, Fernández, Antonio J, Fernández-Pacheco, Borja Camacho, Fitzgerald, J Edward, Fonsi, Giovanni B, Font, Roser Farré, Fowler, Amy L, Fretwell, Kenneth R, Fructuoso, Lorena Sanchon, Fusai, Giuseppe K, Garcia, Miguel Hernandez, Garcia-Ureña, Miguel Angel, Gill, Charn K, Gisbertz, Suzanne S, Del Giudice, Roberto, Giuffrida, Maria Carmela, Di Giuseppe, Matteo, Gómez, María Fanjul, Guariglia, Claudio A, Hainsworth, Alison J, Hall, Bria J, Hall, James RW, Hammond, John S, Haqqani, Maha H, Harrison, Ewen M, Hazelton, Joshua P, van Heinsbergen, Maarten, Hill, Arnold DK, Hing, Caroline B, Hirji, Sameer A, Ho, Michael WS, Holbrook, Charlotte M, Holme, Thomas J, Hopkins, James C, Hopkinson, David N, Hossain, Fahad S, Hudson, Victoria E, Hughes, Jane L, Hwang, E. 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Ardito, Antonella, Arigoni, Michele, Armao, Teodora, Arminio, Armando, Armstrong, Lara, Arnaud, Alexis, Asaad, Peter, Ashcroft, James, Ashmore, Christopher, Asqalan, Ahmad, Asti, Emanuele, Aubry, Emmanuelle, Aytac, Erman, Ayuso-Herrera, Esther, Baeza, Melody, Bailon-Cuadrado, Martin, Bakmaz, Bernarda, Baldi, Caterina, Baldini, Edoardo, Baldo, Stefano, Ballabio, Michele, Baloyiannis, Ioannis, Baltazar, Gerard, Bàmbina, Fabrizio, Bandiera, Alessandro, Barlow, Emma, Barmasse, Roberto, Barmpagianni, Christina, Baronio, Gianluca, Barra, Fabio, Bartsch, Anne-Marie, Basgaran, Amedra, Basha, Amr, Bashkirova, Varvara, Bastazza, Marco, Baumber, Rachel, Belcher, Elizabeth, Belvedere, Angela, Benítez-Linero, Inmaculada, Bergeat, Damien, Bernasconi, Matteo, Bhalla, Ashish, Bhutiani, Neal, Bianco, Federica, Bisagni, Pietro, Blake, Iain, Blanco-Colino, Ruth, Blazquez-Martin, Alma, Boal, Matthew, Bonavina, Luigi, Bonavina, Giulia, Bond-Smith, Giles, Booth, Karen, Borges, Filipe, Borghi, Felice, Bouchagier, Konstantinos, Bourke, Grainne, Boyle, Emily, Brachini, Gioia, Brain, Jessie, Brar, Amanpreet, Breckles, Lisa, Bretagnol, Frédéric, Brixton, Genevieve, Bruzzaniti, Placido, Bueser, Teofila, Burnside, Nathan, Caballero, Albert, Calcerrada-Alises, Enrique, Callahan, Miriam, Camarero, Enrique, Campagnaro, Tommaso, Campanelli, Michela, Candiani, Massimo, Cantalejo-Diaz, Miguel, Cao, Han, Capelli, Patrizio, Capizzi, Vita, Carcano, Giulio, Carissimi, Francesca, Carlini, Massimo, Carlucci, Michele, Carmichael, Heather, Carrasco, Milagros, Carrillo, Mariana, Carvello, Michele, Casati, Massimiliano, Castoro, Carlo, Catalan, Vanesa, Cavaleiro, Salomé, Cellerino, Paola, Centinaio, Giovanna, Cernei, Cristina, Cerro, Cristina, Cervellera, Maurizio, Chakrabortee, Sohini, Chamberlain, Stephanie, Chan, Jeffrey, Chang, Grace, Chaudhry, Dauod, Chebaro, Alexandre, Chen, David, Chetty, Govind, Chia, Zoe, Chiappini, Ambra, Chiarugi, Massimo, Chidambaram, Swathikan, Chiozza, Matteo, Cholewa, Hanna, Chong, Clara, Choolani-Bhojwani, Ekta, Christoforidis, Dimitri, Chui, Karen, Chung, Choyin, Cirillo, Bruno, Citterio, Davide, Clermidi, Pauline, Coccolini, Federico, Colletti, Gaia, Compagnoni, Bruno, Concepción-Martín, Vanesa, Confalonieri, Marco, Connolly, Hannah, Conso, Christel, Conti, Luigi, Cooper, Zara, Cordera, Fernando, Corral, Javier, Costa, Marta, Costanzi, Andrea, Cotsoglou, Christian, Cozza, Valerio, Cuming, Tamzin, Curtis, Miles, Cuschieri, Joseph, D'Agruma, Michele, D'Andrea, Giancarlo, Daliya, Prita, Dare, Oliver, Darko, Ebenezer, Day, Andrew, Dehal, Ahmed, Dehart, Dustin, Delgado-Oliver, Eduardo, Denning, Max, Desai, Anant, Desender, Liesbeth, Dester, Sara, Díaz-García, Alberto, Diaz-Peña, Patricia, Dousset, Bertrand, Doussot, Alexandre, Duchateau, Nicolas, Duff, Sarah, Dunning, Joel, Duque-Mallen, Victoria, Dziakova, Jana, Egan, Bridget, Egan, Richard, El-Ali, Abess, Elfeki, Hossam, Elhadi, Muhammed, Eljareh, Mohammed, Elkady, Ramy, Elkhafeefi, Fatimah, Elmore, Ugo, Elmoslemany, Tarek, Emmerson, Oliver, Enemosah, Ibrahim, English, Camilla, English, William, Escartin, Jorge, Estaire-Gomez, Mercedes, Evans, Luke, Evans, Jessica, Exley, Rebecca, Fabbri, Nicoló, Falco, Giuseppe, Familiari, Pietro, Fancellu, Alessandro, Farik, Shebani, Farrell, Tony, Fehervari, Matyas, Fell, Adam, Fernandez-Camuñas, Angel, Fernández-Marín, Reyes, Fernández-Martínez, María, Ferrara, Francesco, Ferrari, Guglielmo, Ferrero, Simone, Findlay, Laura, Fiore, Marco, Fiori, Enrico, Flatman, Michael, Flindall, Ian, Flor, Blas, Fontana, Tommaso, Ford, Samuel, Ford, David, Forlani, Stefano, Francone, Elisa, Frattaruolo, Colomba, Frio, Federico, Gagliano, Annalisa, Gagliardi, Filippo, Gahunia, Sukhpreet, Gaino, Francesca, Gala, Tanzeela, Galfrascoli, Elisa, Galimberti, Luca, Gallagher, Phoebe, Galleano, Raffaele, Galván-Pérez, Armando, Gammeri, Emanuele, Ganau, Mario, Garcés-García, Raúl, Garulli, Gianluca, Gascon-Ferrer, Isabel, Gattolin, Andrea, Gaujoux, Sebastien, Gentilli, Sergio, Georgiades, Fanourios, Ghanbari, Amir, Ghosh, Dhruv, Giacometti, Marco, Giblin, Anna-Victoria, Gilbert, Catherine, Giménez, Clara, Giorgakis, Emmanouil, Gipponi, Manuel, Glen, Paul, Goatly, Giles, Gobatti, Davide, Godbole, Chintamani, Gohil, Kajal, Gómez, Marcos, Gomez-Rosado, Juan-Carlos, Gonullu, Emre, Gonzalez-Gonzalez, Enrique, Gordini, Luca, Gracia, Isabel, Gracia-Roche, Carlos, Granieri, Stefano, Green, Susanna, Grivon, Manuela, Grove, Thomas, Guaglio, Marcello, Guaitoli, Eleonora, Guglielmi, Alfredo, Guha, Soumya, Gustavino, Claudio, Habeeb, Amir, Hagger, Robert, Hakmi, Hazim, Halkias, Constantine, Hall, Claire, Hampton, Matthew, Handa, Siddhartha, Hansen, Laura, Haq, Iram, Harky, Amer, Harries, Rhiannon, Harrison, Joseph, Hasan, Raashad, Hawari, Mohammad, Hawkin, Paul, Hebblethwaite, Bethany, Henriques, Susana, Heritage, Emily, Hernandez-Juara, Pilar, Herrero-Lopez, Maria, Hervieux, Erik, Heyd, Bruno, Higgs, Simon, Hitchman, Louise, Ho, Beatrice, Hogan, Aisling, Hölzle, Frank, Hossain, Tanvir, Hurt, Libor, Hutchinson, Peter, Iacob, Giulio, Iannone, Immacolata, Ibrahim, Sherif, Iovino, Domenico, Isik, Arda, Jafarova, Sevda, Jamil, Tahir, Jayaraju, Ullas, Jenner, Edward, Jimenez-Higuera, Elisa, Jimeno, Jaime, Jones, Mark, Judkins, Nicholas, Kalavrezos, Nicholas, Kalidindi, Venugopala, Kalkat, Maninder, Kamal, Mona, Kamphues, Carsten, Kang, Chong, Kara, Yasin, Karam, Edward, Karim, Ahmed, Kashora, Florence, Kearney, David, Khajuria, Apoorva, Khan, Umul, Khan, Azam, Khatri, Chetan, Kinnaman, Gabriel, Kinross, James, Kler, Aaron, Klimopoulos, Serafeim, Kocataş, Ali, Kolias, Angelos, Königsrainer, Alfred, Konsten, Joop, Kontovounisios, Christos, Kourdouli, Amar, Krishnan, Emily, Kristinsson, Sverrir, Kruijff, Schelto, Kudsk-Iversen, Søren, Kufeji, Dorothy, Kugler, Nadav, Kulkarni, Rugved, Kurihara, Hayato, Laface, Letizia, Lakkis, Zaher, Lami, Mariam, Landaluce-Olavarria, Aitor, Lapolla, Pierfrancesco, Lawani, Ismail, Lawday, Samuel, Lázaro, André, Lecolle, Katia, Leventoglu, Sezai, Li, Zoe, Liew, Ignatius, Lisi, Giorgio, Lizzi, Vincenzo, Lo, Terence, Lomiento, Daniele, Longhi, Marco, Lostis, Emilie, Lostoridis, Eftychios, Loubani, Mahmoud, Lowy-Benoliel, Alejandro, Lucianetti, Alessandro, Luke, Louis, Lunevicius, Raimundas, Luraghi, Marco, Lye, George, Mabrouk, Islam, Macchi, Alberto, MacDonald, Luisa, Machairas, Nikolaos, Madonini, Marco, Magowan, Drew, Maisonneuve, Emeline, Majkowska, Agata, Majkowski, Lawrence, Mak, Jason, Malabarba, Stefano, Malerba, Michele, Mannan, Syed, Manson, Joanna, Mansuri, Ahmer, Mantoglu, Baris, Manu, Nichola, Maqsood, Afnan, Marano, Alessandra, Marchbank, Adrian, Marcos-Santos, Pablo, Marrano, Enrico, Martin, Janet, Martin, Emmeline, Martin, Guy, Martin-Albo, Lorena, Martín-Román, Lorena, Martinelli, Fabio, Martínez-dePaz, Fernando, Martinez-German, Antonio, Martinez-Pinedo, Carlos, Martins, Ricardo, Marwan, Hisham, Marzi, Federica, Mathieu, Pierre, Matute-Najarro, Maria-Soledad, Maw, Andrew, Mazingi, Dennis, Mazzaferro, Vincenzo, McCanny, Andrew, McKenzie, Katherine, McLarty, Nicola, McPherson, Iain, Medina, Esther, Mediratta, Saniya, Medone, Marzia, Mehra, Gautam, Mele, Simone, Melero-Cortés, Lidia, Mendoza-Moreno, Fernando, Meneghini, Simona, Mercante, Giuseppe, Merdrignac, Aude, Merola, Stephen, Metallidis, Symeon, Michel, Martin, Migliore, Marco, Mihanovic, Jakov, Miller, Douglas, Mingoli, Andrea, Minto, Gary, Mirabella, Antonello, Misra, Nikhil, Mitrasinovic, Stefan, Miu, Victor, Moawad, Nader, Mochet, Sylvie, Modabber, Ali, Mohammad, Adam, Mohan, Midhun, Moliner-Sánchez, Carmen, Mongelli, Francesco, Monteleone, Michela, Montuori, Mauro, Moore, Rachel, Mora-Guzmán, Ismael, Morales, Xavier, Morales, Dieter, Morelli, Luca, Morelli, Lucia, Morgan, Richard, Morris, Chris, Mortini, Pietro, Mosca, Angelo, Motter, Dema, Moug, Susan, Mukherjee, Samrat, Najdy, Manhal, Nakas, Apostolos, Namazov, Ilgar, Naredla, Pradyumna, Nasef, Emmhamed, Nassa, Heeam, Nath, Rahul, Navarro-Sánchez, Antonio, Nazarian, Scarlet, Negri, Giampiero, Nehra, Deepika, Neil-Dwyer, Jason, Neri, Jacopo, Newton, Katy, Nikaj, Herald, Niquen, Milagros, Nobile, Sara, Nogueiro, Jorge, Ntirenganya, Faustin, Nugent, Michael, Núñez, Jordi, Ocaña, Juan, Okechukwu, Valentine, Oliva-Mompean, Fernando, Oliveira, Ana, Ollat, Didier, Onos, Lavinia, Osagie-Clouard, Liza, Osman, Khabab, Ottolina, Jessica, Ourieff, Jared, Outani, Oumaima, Oyewole, Bankole, Ozben, Volkan, Pacheco-Sanchez, David, Padilla-Valverde, David, Pai, Madhava, Paiella, Salvatore, Paisley, Samuel, Palini, Gianmarco, Palmeri, Matteo, Panahi, Pedram, Parente, Alessandro, Parlanti, Daniele, Parmar, Chetan, Pascual, Angela, Patel, Mahul, Pathak, Abhijit, Patil, Sangram, Pattyn, Piet, Peckham-Cooper, Adam, Pedrazzani, Corrado, Pellino, Gianluca, Peluso, Chiara, Pereira, André, Pereira-Neves, António, Perez-Diaz, MD, Pérez-González, Marta, Pérez-Saborido, Baltasar, Perivoliotis, Konstantinos, Perkins, Clare, Peros, Georgios, Perotto, Ornella, Perra, Teresa, Petrone, Patrizio, Phenix, George, Picazo, Sara, Picon-Rodriguez, Rafael, Piloni, Martina, Pingarrón-Martín, Lorena, Pinotti, Enrico, Pisanu, Adolfo, Pizzini, Paolo, Pockney, Peter, Podda, Mauro, Podolsky, Dina, Poggioli, Gilberto, Pompili, Cecilia, Pontari, Michael, Porcu, Alberto, Potter, Ryan, Price, Claire, Pruvot, François-René, Pujol-Muncunill, Roger, Puppo, Andrea, Quante, Markus, Quintana-Villamandos, Begoña, Qureshi, Ali, Radenkovic, Dejan, Rakvin, Ivan, Ramallo-Solís, Irene, Ramcharan, Sean, Ramos, Diego, Ramos-Bonilla, Antonio, Ramzi, Joussi, Rathinam, Sridhar, Rausa, Emanuele, Ravaioli, Matteo, Ravindran, Sharanya, Raymond, Thomas, Razik, Aisha, Redfern, Jennifer, Reguera-Rosal, Julio, Rela, Mariam, Rey-Biel, Juan, Rey-Valcarcel, Cristina, Ribolla, Marta, Richards, Tomos, Richmond, Michael, Righini, Erminio, Rio-Gomez, Javier, Riyat, Harjoat, Rizvi, Sana, Roberts, Keith, Roberts, Matthew, Robertson, Stuart, Robertson, Ronald, Robin-Valle, Alvaro, Rochon, Melissa, Rojo, Mikel, Rolli, Luigi, Romano, Silvio, Ross, Elizabeth, Ross, Howard, Rossborough, Catherine, Rottoli, Matteo, Ruiz-Grande, Fernando, Ruiz-Martin, Irene, Ruiz-Soriano, María, Ruzzenente, Andrea, Ryska, Ondrej, Saez, Carlos, Sagnotta, Andrea, Sahnan, Kapil, Sahni, Arun, Salim, Ali, Sallam, Ibrahim, Salvia, Roberto, Samadov, Elgun, Sammarco, Giuseppe, Sampaio-Alves, Mafalda, Sánchez-Arteaga, Alejandro, Sanchez-Fuentes, Maria-Nieves, Sanchez-Pelaez, Daniel, Sanchez-Perez, Coral, Sanchez-Rubio, Maria, Sancho-Muriel, Jorge, Sanders, Julie, Santero-Ramirez, Maria-Pilar, Santora, Thomas, Santoro, Antonio, Santos, Irene, Santos-Sousa, Hugo, Sapienza, Paolo, Sartarelli, Lodovico, Sarveswaran, Janahan, Sasia, Diego, Saudemont, Alain, Saudi-Moro, Sef, Saxena, Shobhit, Saxena, Dolly, Sayasneh, Ahmad, Scalabre, Aurelien, Schache, Andrew, Schiavina, Riccardo, Schineis, Christian, Schreckenbach, Teresa, Scorza, Antonella, Scott, Lucy, Seegert, Sara, Seguin-Givelet, Agathe, Senent-Boza, Ana, Seymour, Keith, Shabana, Amanda, Shah, Karishma, Shah, Jigar, Shah, Preena, Shah, Sujay, Shakir, Taner, Shalaby, Mostafa, Shankar, Sushma, Shaw, Richard, Shehata, Sameh, Shenfine, Amy, Sheridan, Kelda, Sherief, Ahmed, Sherief, Mohamed, Sherif, Mohamed, Shinkwin, Michael, Shu, Sebastian, Siaw-Acheampong, Kwabena, Sileri, Pierpaolo, Singh, Abhinav, Singh, Shailendra, Sinha, Sanjay, Sinha, Deepti, Siragusa, Leandro, Sivaprakasam, Rajesh, Sivayoganathan, Sriharan, Smillie, Robert, Smith, Claire, Smith, Andrew, Smith, Christopher, Sochorova, Dana, Soggiu, Fiammetta, Sohrabi, Catrin, Solari, Francesca, Solli, Piergiorgio, Soreide, Kjetil, Spinelli, Antonino, Spoletini, Domenico, Spriano, Giuseppe, Sravanam, Sanskrithi, Ssentongo, Paddy, Stanger, Sophie, Stavroulias, Dionisios, Steel, Ben, Stella, Marco, Stewart, Robbie, Stringer, Sally, Sulen, Nina, Sundar, Sudha, Sundhu, Matthew, Suri, Avni, Syed, Arooj, Szatmary, Peter, Tabiri, Stephen, Tadross, Daniel, Taglietti, Lucio, Tansey, 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Aloka S D, Al Maadany, Faraj S, De Marchi, Joshua A, Ramos-De la Medina, Antonio, Mithany, Reda H M, Sanchez del Pueblo, Cristina, van Ramshorst, Gabriëlle, De Salas, Maria Marqueta, De Souza, Anthony C, Dolores Del Toro, M, Archer, James E, Odeh, Abdulrahman, Erridge, Simon, Salem, Hosni Khairy, Jones, Gareth P, Gardner, Anne, Tripathi, Shiva S, Gregg, Anne, Jeganathan, Reuben, Siddique, Muhammad Harris, Lombardi, Celestino P, Martin, Benjamin, Leo, Cosimo Alex, Dass, Debashis, Di Franco, Gregorio, Jiao, Long R, Mari, Giulio Maria, Capitan-Morales, Luis-Cristobal, Connelly, Tara M, Alanbuki, Ammar, De Virgilio, Armando, Schilling, Clare, San Miguel Mendez, Carlos, Kulkarni, Gauri, Nizami, Kulsoom, Walsh, Stewart, Dean, Harry, Ruiz-Marin, Miguel, Houston, Rory, Trompetto, Mario, Chrastek, David, Kouritas, Vasileios, Cannoletta, Maria, Rosato, Francesco, Kaushal, Manish V, Costa, Paulo Matos, Elkadi, Hannah H, Johnstone, Jack R, Irvine, Esmee, Alvarez, Maria R, Corbellini, Carlo, Venkatesan, Gowtham S, Mateo-Sierra, Olga, Martínez-Pérez, Carolina, Serrano González, Javier, Hernández Bartolomé, Miguel Ángel, Díaz Pérez, David, Gutiérrez Samaniego, María, Galindo Jara, Pablo, Sharma, Neil, Smart, Neil J, Keller, Deborah S, COVIDsurg Collaborative, [missing], Nepogodiev, Dmitri, Glasbey, James C, Li, Elizabeth, Omar, Omar M, Simoes, Joana FF, Abbott, Tom EF, Alser, Osaid, Arnaud, Alexis P, Bankhead-Kendall, Brittany K, Breen, Kerry A, Cunha, Miguel F, Davidson, Giana H, Di Saverio, Salomone, Gallo, Gaetano, Griffiths, Ewen A, Gujjuri, Rohan R, Hutchinson, Peter J, Kaafarani, Haytham MA, Lederhuber, Han, Löffler, Markus W, Mashbari, Hassan N, Minaya-Bravo, Ana, Morton, Dion G, Moszkowicz, David, Pata, Francesco, Tsoulfas, George, Venn, Mary L, Bhangu, Aneel, Cox, Daniel, Roslani, April C, Alakaloko, Felix, de Vries, Jean-Paul PM, Aaraj, Mahmoud A, Abbott, Sarah J, Abdalla, Mutwakil OM, Abdelaal, Ahmed S, Ademuyiwa, Adesoji O, Aherne, Thomas M, Ali, Osman M, Alkadeeki, Ghadah Z, Almeida, Ana C, Alrahawy, Mahmoud M, Ambler, Graeme K, Alameer, Ehab, Andreani, Stefano M, De Andrés-Asenjo, Beatriz, Antonanzas, Leyre Lopez, Aoun, Salah G, Ashoush, Fouad M, Augestad, Knut Magne, Avellana, Rocio B, Ayeni, Funbi A, Ayorinde, John OO, Babu, Bheemanakone H, Baig, Mirza MAS, Bajomo, Oreoluwa M, Baker, Olivia J, Baker, Markus P, Baldwin, Alexander J, Ban, Vin Shen, Baron, Ryan D, Barranquero, Alberto G, Barry, Conor P, DI Bartolomeo, Alessandro, Bass, Gary A, Bath, Michael F, Batjer, H Hunt, Beamish, Andrew J, Belgaumkar, Ajay P, Bence, Matthew N, Benson, Ruth A, Bernal-Sprekelsen, Juan Carlo, Bhama, Anuradha R, Bhavaraju, Avi V, Biffl, Walter L, Blundell, Chris M, Boddy, Alexander P, Borgstein, Alexander BJ, Bosanquet, David C, Bosch, Karen D, Bouhuwaish, Ahmad EM, Bozkurt, Mehmet A, Brathwaite, Collin EM, Brown, Benjamin C, Brown, Oliver D, Brown, Allison K, Buarque, Igor Lima, Bueno-Cañones, Alejandro D, Bulugma, Mustafa R, Burke, Joshua R, Byrne, Matthew HV, Cagigal-Ortega, Elima P, Callcut, Rachael A, DI Candido, Francesca, Canova, Michaela E, Carlos, William J, Caruana, Edward J, Cato, Liam D, Catton, Andrew B, Ceretti, Andrea Pisani, Chase, Thomas JG, Chiara, Francesco Di, Chowdhury, Abeed H, Chung, Eric A, Cicerchia, Pierfranco M, Clough, Ethan CS, Coleman, Natasha L, Collins, Chris G, Collins, Michelle L, Colonna, Emily T, Comini, Lara V, Connolly, Tara M, Coughlin, Patrick A, Cruzado, Laura Fernández-Gomez, Davidson, Brian R, Davies, Richard J, Davies, Emma J, Davis, Niall F, Dawson, Brett E, Dean, Benjamin JF, Delgado, Maria Garcia-Conde, Diaz, Jose J, Dickson, Kathryn E, Diez-Alonso, Manuel M, Dixon, Jan R, Doe, Matthew J, Drake, Thomas D, Drake, Frederick T, Duffy, John P, Dunne, Declan FJ, Dunne, Naomi JM, Durán-Muñoz-Cruzado, Virginia M, Durst, Alexander ZE, Eardley, Nicola J, Edwards, John G, Elfallal, Ahmed H, Elfiky, Mahmoud MA, Elliott, Jessie A, Emile, Sameh H, Emslie, Katy M, Endorf, Frederick W, Engel, Jamie L, Enjuto, Diego T, Etchill, Eric W, Evans, Jonathan P, Fahey, Brian A, Faria, Carlos S, Feo, Carlo V, Ferguson, Henry JM, Fernandez, Beatriz Dieguez, Fernandez, Andres Garcia, Fernández, Antonio J, Fernández-Pacheco, Borja Camacho, Fitzgerald, J Edward, Fonsi, Giovanni B, Font, Roser Farré, Fowler, Amy L, Franco, Gregorio Di, Fretwell, Kenneth R, Fructuoso, Lorena Sanchon, Fusai, Giuseppe K, Garcia, Miguel Hernandez, Garcia-Ureña, Miguel Angel, Gill, Charn K, Gisbertz, Suzanne S, Del Giudice, Roberto, Giuffrida, Maria Carmela, Di Giuseppe, Matteo, Gómez, María Fanjul, González, Javier Serrano, Guariglia, Claudio A, Hainsworth, Alison J, Hall, Bria J, Hall, James RW, Hammond, John S, Haqqani, Maha H, Harrison, Ewen M, Hazelton, Joshua P, van Heinsbergen, Maarten, Hill, Arnold DK, Hing, Caroline B, Hirji, Sameer A, Ho, Michael WS, Holbrook, Charlotte M, Holme, Thomas J, Hopkins, James C, Hopkinson, David N, Hossain, Fahad S, Hudson, Victoria E, Hughes, Jane L, Hwang, E. 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Elkhafeefi F., Elmore U., Elmoslemany T., Emmerson O., Enemosah I., English C., English W., Escartin J., Estaire-Gomez M., Evans L., Evans J., Exley R., Fabbri N., Falco G., Familiari P., Fancellu A., Farik S., Farrell T., Fehervari M., Fell A., Fernandez-Camunas A., Fernandez-Marin R., Fernandez-Martinez M., Ferrara F., Ferrari G., Ferrero S., Findlay L., Fiore M., Fiori E., Flatman M., Flindall I., Flor B., Fontana T., Ford S., Ford D., Forlani S., Francone E., Frattaruolo C., Frio F., Gagliano A., Gagliardi F., Gahunia S., Gaino F., Gala T., Galfrascoli E., Galimberti L., Gallagher P., Galleano R., Galvan-Perez A., Gammeri E., Ganau M., Garces-Garcia R., Garulli G., Gascon-Ferrer I., Gattolin A., Gaujoux S., Gentilli S., Georgiades F., Ghanbari A., Ghosh D., Giacometti M., Giblin A.-V., Gilbert C., Gimenez C., Giorgakis E., Gipponi M., Glen P., Goatly G., Gobatti D., Godbole C., Gohil K., Gomez M., Gomez-Rosado J.-C., Gonullu E., Gonzalez-Gonzalez E., Gordini L., Gracia I., Gracia-Roche C., Granieri S., Green S., Grivon M., Grove T., Guaglio M., Guaitoli E., Guglielmi A., Guha S., Gustavino C., Habeeb A., Hagger R., Hakmi H., Halkias C., Hall C., Hampton M., Handa S., Hansen L., Haq I., Harky A., Harries R., Harrison J., Hasan R., Hawari M., Hawkin P., Hebblethwaite B., Henriques S., Heritage E., Hernandez-Juara P., Herrero-Lopez M., Hervieux E., Heyd B., Higgs S., Hitchman L., Ho B., Hogan A., Holzle F., Hossain T., Hurt L., Hutchinson P., Iacob G., Iannone I., Ibrahim S., Iovino D., Isik A., Jafarova S., Jamil T., Jayaraju U., Jenner E., Jimenez-Higuera E., Jimeno J., Jones M., Judkins N., Kalavrezos N., Kalidindi V., Kalkat M., Kamal M., Kamphues C., Kang C., Kara Y., Karam E., Karim A., Kashora F., Kearney D., Khajuria A., Khan U., Khan A., Khatri C., Kinnaman G., Kinross J., Kler A., Klimopoulos S., Kocatas A., Kolias A., Konigsrainer A., Konsten J., Kontovounisios C., Kourdouli A., Krishnan E., Kristinsson S., Kruijff S., Kudsk-Iversen S., Kufeji 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Mendoza-Moreno F., Meneghini S., Mercante G., Merdrignac A., Merola S., Metallidis S., Michel M., Migliore M., Mihanovic J., Miller D., Mingoli A., Minto G., Mirabella A., Misra N., Mitrasinovic S., Miu V., Moawad N., Mochet S., Modabber A., Mohammad A., Mohan M., Moliner-Sanchez C., Mongelli F., Monteleone M., Montuori M., Moore R., Mora-Guzman I., Morales X., Morales D., Morelli L., Morgan R., Morris C., Mortini P., Mosca A., Motter D., Moug S., Mukherjee S., Najdy M., Nakas A., Namazov I., Naredla P., Nasef E., Nassa H., Nath R., Navarro-Sanchez A., Nazarian S., Negri G., Nehra D., Neil-Dwyer J., Neri J., Newton K., Nikaj H., Niquen M., Nobile S., Nogueiro J., Ntirenganya F., Nugent M., Nunez J., Ocana J., Okechukwu V., Oliva-Mompean F., Oliveira A., Ollat D., Onos L., Osagie-Clouard L., Osman K., Ottolina J., Ourieff J., Outani O., Oyewole B., Ozben V., Pacheco-Sanchez D., Padilla-Valverde D., Pai M., Paiella S., Paisley S., Palini G., Palmeri M., Panahi P., Parente A., Parlanti 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Vidya R., Vieira P., Vijay V., Vimalachandran D., Violante T., Volpe A., Vovola F., Vulliamy P., Wall R., Wallwork K., Ward A., Warwick D., Waseem S., Weaver H., Wells F., Wen J., West R., Whitehall E., Wild L., Wilkins A., Williams G., Williams M., Winnand P., Wong K., Worku D., Wright N., Yalamanchili S., Yershov D., Yildiz A., Young R., Yurttas C., Zadegan F., Zafar N., Zakaria R., Zambon M., Zanini N., Zarate A., Zerbib P., Zizzo M., Zmora O., Zonta S., van Berge Henegouwen M.I., van der Plas W.Y., Ali I.A.M., Bakri N.A.C., Bauset J.C.C., Abou Chaar M.K., Marino Cosentino L.M., Gomez Diaz C.J., Garcia Galocha J.L., de Gheldere C.A., Ataide Gomes G.M., Beltran de Heredia J., Blazer III D.G., Nugent III W.C., Ali karar A.A., Borja De Lacy F., Blas Laina J.L., Shane Lester M.J., Liyanage A.S.D., Al Maadany F.S., De Marchi J.A., Ramos-De la Medina A., Mithany R.H.M., Sanchez del Pueblo C., van Ramshorst G.H., De Salas M.M., De Souza A.C., Dolores Del Toro M., Archer J.E., Odeh A., Erridge S., Salem H.K., Jones G.P., Gardner A., Tripathi S.S., Gregg A., Jeganathan R., Siddique M.H., Lombardi C.P., Martin B., Leo C.A., Dass D., Di Franco G., Jiao L.R., Mari G.M., Capitan-Morales L.-C., Connelly T.M., Alanbuki A., De Virgilio A., Schilling C., San Miguel Mendez C., Kulkarni G., Nizami K., Walsh S., Dean H., Ruiz-Marin M., Houston R., Trompetto M., Chrastek D., Kouritas V., Cannoletta M., Rosato F., Kaushal M.V., Costa P.M., Elkadi H.H., Johnstone J.R., Irvine E., Alvarez M.R., Corbellini C., Venkatesan G.S., Mateo-Sierra O., Martinez-Perez C., Serrano Gonzalez J., Hernandez Bartolome M.A., Diaz Perez D., Gutierrez Samaniego M., Galindo Jara P., Sharma N., Smart N.J., Keller D.S., AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Surgery, Graduate School, Almaadany, F. 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E., Odeh, A., Stewart, R., Ullah, R., Armstrong, L., Jones, M., Aljanadi, F., Moawad, N., Gregg, A., Jeganathan, R., Ferguson, H. J. M., Ramcharan, S., Yershov, D., Hopkins, J. C., Doe, M. J., Ambler, G. K., Lostis, E., Lawday, S., Babu, B. H., Liyanage, A. S. D., Weerasinghe, C. K., Blake, I., Sanders, J., Bueser, T., Curtis, M., Oo, A. Y., Abbott, T. E. F., Anwar, S., Sohrabi, C., Williams, K. J., Chung, E. A., Hagger, R., Karim, A., Hainsworth, A. J., Flatman, M., Hing, C. B., Trompeter, A., Lo, T., Wade, R. G., Bourke, G., Burke, J. R., Young, A. L., Wall, J. J. S., Johnstone, J. R., Peckham-Cooper, A., Elkadi, H. H., Kowal, M. R., Pompili, C., Ho, M. W. S., Kinross, J., Ibrahim, M. A. H., Abuown, A., Denning, M., Erridge, S., Yalamanchili, S., Martin, G., Hall, C., Hall, J. R. W., Baldwin, A. J., Gammeri, E., West, R., Wormald, J. C. R., Catton, A. B., Kudsk-Iversen, S., Kouris, S. M., Nugent, M., Lin, D. J., Kang, C., Scurrah, R. J., Rajgor, A. 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K., Chung, C., Hansen, L., Okafor, B. U., Roxo, V. I., Rice, H. E., Hwang, E. S., Blazer, D. G., Hall, B. J., Olson, S. A., Nehra, D., Cuschieri, J., Davidson, G. H., Walters, A. M., Nygaard, R. M., Colonna, E. T., Endorf, F. W., Meagher, A. D., Kinnaman, G., Mckenzie, K., Fretwell, K. R., Chan, J., Nugent, W. C., Chen, D., Stevens, K. A., Etchill, E. W., Jenny, H. E., Dehal, A., Kaafarani, H. M., Breen, K. A., Bankhead-Kendall, B. K., Alser, O., Mashbari, H. N., Velmahos, G. C., Chang, G., Dehart, D., Ourieff, J., Merola, S., Volpe, A., Podolsky, D., Coleman, N. L., Callahan, M., Brathwaite, C. E. M., Liu, H. H., Petrone, P., Baltazar, G., Hakmi, H., Sohail, A. H., Hazelton, J. P., Ssentongo, A. E., Ssentongo, P., Jamil, T., Al-Embideen, S., Seegert, S., Torquati, A., Bhama, A. R., Biffl, W. L., Schaffer, K. B., Marsh, C. L., Philp, M. M., Ross, H., Santora, T., Pathak, A., Sewards, J. M., Pontari, M., Engel, J. L., Giorgakis, E., Bhavaraju, A. V., Kalkwarf, K. J., Roberts, M., Robertson, R., Callcut, R. A., Canova, M. E., Suri, A., Velopulos, C. G., Carmichael, H., Mcintyre, R. C., Wright, F. L., Urban, S., Martin, R. C. G., Bhutiani, N., Diaz, J. J., Abdou, H., O'Meara, L. B., Richmond, M., Almasri, M., Marwan, H., Mehdi, M. Q., Kulkarni, G., Ban, V. S., Aoun, S. G., Batjer, H. H., Bhangu, A., Guided Treatment in Optimal Selected Cancer Patients (GUTS), ​Robotics and image-guided minimally-invasive surgery (ROBOTICS), and Universidad de Cantabria

Subjects
Male, Emergency Medical Services, Respiratory Tract Diseases, Coronavirus Infections/complications, sars cov2, Settore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIO, 030204 cardiovascular system & hematology, SARS-CoV-2, acute respiratory syndrome, pulmonary complication, 0302 clinical medicine, Postoperative Complications, Retrospective Studie, CONSENSUS DEFINITIONS, Epidemiology, Medicine and Health Sciences, Medicine, Surgery, Postoperative complications, Mortality, COVID-19, 030212 general & internal medicine, Hospital Mortality, Viral, Respiratory Tract Disease, 11 Medical and Health Sciences, Mortality rate, Covid19, Operative/adverse effects, General Medicine, Middle Aged, Elective Surgical Procedures/adverse effects, Operative, Elective Surgical Procedures, Surgical Procedures, Operative, Female, COVID-19. Global surgery. Perioperative SARS-CoV-2 infection. International cohort study, Coronavirus Infections, Human, Cohort study, Surgical Procedures, Operative/adverse effects, Adult, medicine.medical_specialty, Respiratory Tract Diseases/etiology, Pneumonia, Viral, NO, COVIDSurg Collaborative, 03 medical and health sciences, Viral/complications, Betacoronavirus, Young Adult, General & Internal Medicine, Humans, Mortality, Elective surgery, Pandemics, LS7_4, Aged, Retrospective Studies, Surgical Procedures, Betacoronaviru, Elective Surgical Procedure, Pandemic, Coronavirus Infection, Emergency Medical Service, business.industry, No key words available, Postoperative complication, COVID-19, Retrospective cohort study, Odds ratio, Perioperative, Pneumonia, Surgery, Pneumonia, Viral/complications, Postoperative Complication, business
Abstract

The lancet 396(10243), 27-38 (2020). doi:10.1016/S0140-6736(20)31182-X, Published by Elsevier, London [u.a.]

Published
2020

39. Effects of a wearable technology-based physical activity intervention on sleep quality in breast cancer survivors: the ACTIVATE Trial

Author

Melissa M. Moore, Matthew P. Buman, Terry Boyle, Jeff K. Vallance, Dori E. Rosenberg, Christine M. Friedenreich, Brigid M. Lynch, Dallas R. English, Shakira Milton, Marina M. Reeves, Nga H. Nguyen, Nguyen, Nga H., Vallance, Jeff K., Buman, Matthew P., Moore, Melissa M., Reeves, Marina M., Rosenberg, Dori E., Boyle, Terry, Milton, Shakira, Friedenreich, Christine M., English, Dallas R., and Lynch, Brigid M.

Subjects
medicine.medical_specialty, Health coaching, physical activity, law.invention, Pittsburgh Sleep Quality Index, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Randomized controlled trial, law, Intervention (counseling), accelerometry, breast neoplasms, Medicine, 030212 general & internal medicine, Oncology (nursing), business.industry, Actigraphy, fitness trackers, medicine.disease, Oncology, 030220 oncology & carcinogenesis, Physical therapy, Sleep onset latency, Sleep onset, business
Abstract

Introduction: Physical activity interventions can improve sleep quality in breast cancer survivors. This paper examines the effects of the ACTIVATE Trial, a wearable-based physical activity intervention (Garmin Vivofit2® coupled with behavioral feedback, goal setting, and health coaching) on sleep outcomes. Methods: Post-primary treatment, inactive, postmenopausal breast cancer survivors were recruited and randomized to primary intervention or waitlist. Wrist-worn actigraphy (sleep onset latency, SOL; total sleep time, TST; sleep efficiency, SE; wake after sleep onset, WASO; and number of awakenings, NWAKE) and questionnaire-derived sleep measures (Pittsburgh Sleep Quality Index) were assessed at baseline (T1), 12 weeks (end of primary intervention and start of waitlist intervention, T2), and at 24 weeks (T3). Results: Eighty-three women (mean age = 62 years) were randomized; trial retention was 94% at T2 and 87% at T3. At T2, primary intervention participants had greater improvements in WASO (− 5.7 min, 95% CI − 11.7 to − 0.2) and NWAKE compared with the waitlist arm (− 2.0, 95% CI − 3.6 to − 0.4). At T3, within-group improvements were observed for SE (both groups), WASO (both groups), NWAKE (primary intervention group only), total PSQI score (primary intervention group), and sleep efficacy (primary intervention group). Conclusions: The intervention reduced actigraphy-measured sleep disturbances. Within-group analyses suggest that improvements in sleep quality are sustained over a longer duration, and there may be similar benefits from an abridged intervention (wearable device only). Actigraphy-measured effects appeared stronger in participants who were poor sleepers at study entry. Implications for Cancer Survivors: Wearable technology can increase physical activity and improve sleep for breast cancer survivors Refereed/Peer-reviewed

Published
2020

40. Comparative analysis of surgical and percutaneous pulmonary valve implants over a 20-year period

Author

John Thomson, Carin Van Doorn, Kate English, Ines Hribernik, James R. Bentham, Andrew Ho, and Osama Jaber

Subjects
Pulmonary and Respiratory Medicine, Cardiac Catheterization, medicine.medical_specialty, Percutaneous, Pulmonary Valve Replacement, Internal medicine, medicine.artery, medicine, Humans, Ventricular outflow tract, Retrospective Studies, Heart Valve Prosthesis Implantation, Pulmonary Valve, business.industry, Retrospective cohort study, General Medicine, medicine.disease, Pulmonary Valve Insufficiency, Stenosis, Treatment Outcome, medicine.anatomical_structure, Heart Valve Prosthesis, Infective endocarditis, Pulmonary valve, Pulmonary artery, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract

OBJECTIVES Since percutaneous pulmonary valve implantation (PPVI) was introduced to prolong the lifetime of surgically placed right ventricular to pulmonary artery conduits, valve technology has evolved and the indications for PPVI expanded to native and larger right ventricular outflow tracts. We explore how indications, patient populations and outcomes compare to surgical pulmonary valve replacement (PVR). METHODS This is a retrospective cohort study of PPVI and PVR procedures between 1998 and 2020 at a single UK centre. One hundred and twenty-eight patients underwent PPVI and 365 patients PVR. Primary outcome measures were survival, infective endocarditis and reintervention. RESULTS The most common indication for PVR was replacement of the native pulmonary valve for pulmonary regurgitation whereas PPVI was more commonly used to treat pulmonary stenosis in a previously placed bioprosthetic conduit or valve. Treatment indications for PPVI expanded over the study to include the native right ventricular outflow tract. Survival was similar for PPVI and PVR (92% PPVI and 96.8% PVR at 5 years; 85.8% PPVI and 95.1% PVR at 10 years). Preprocedural New York Heart Association class 3 and 4 was the most important predictor of poor outcome. Annualized infective endocarditis rate was significantly higher for the Melody PPVI (0.024 vs 0.0024/person/year for PVR, P CONCLUSIONS An increasing number of patients requiring PVR can now be treated percutaneously. A lifetime strategy for re-valving should be considered at the first valve implant.

Published
2021

41. Bioacoustic classification of avian calls from raw sound waveforms with an open-source deep learning architecture

Author

Francisco J. Bravo Sanchez, Rahat Hossain, Nathan B. English, and Steven T. Moore

Subjects
Computer science, Bioacoustics, media_common.quotation_subject, Science, Feature extraction, Fidelity, Machine learning, computer.software_genre, Article, Birds, Machine Learning, Software, Deep Learning, Animals, media_common, Hyperparameter, Multidisciplinary, Artificial neural network, business.industry, Conservation biology, Deep learning, Acoustics, Statistical classification, Sound, Medicine, Artificial intelligence, Neural Networks, Computer, Vocalization, Animal, business, computer, Algorithms
Abstract

The use of autonomous recordings of animal sounds to detect species is a popular conservation tool, constantly improving in fidelity as audio hardware and software evolves. Current classification algorithms utilise sound features extracted from the recording rather than the sound itself, with varying degrees of success. Neural networks that learn directly from the raw sound waveforms have been implemented in human speech recognition but the requirements of detailed labelled data have limited their use in bioacoustics. Here we test SincNet, an efficient neural network architecture that learns from the raw waveform using sinc-based filters. Results using an off-the-shelf implementation of SincNet on a publicly available bird sound dataset (NIPS4Bplus) show that the neural network rapidly converged reaching accuracies of over 65% with limited data. Their performance is comparable with traditional methods after hyperparameter tuning but they are more efficient. Learning directly from the raw waveform allows the algorithm to select automatically those elements of the sound that are best suited for the task, bypassing the onerous task of selecting feature extraction techniques and reducing possible biases. We use publicly released code and datasets to encourage others to replicate our results and to apply SincNet to their own datasets; and we review possible enhancements in the hope that algorithms that learn from the raw waveform will become useful bioacoustic tools.

Published
2021

42. The Effects of Interrupting Prolonged Sitting With Frequent Bouts of Light-Intensity Standing Exercises on Blood Pressure in Stroke Survivors: A Dose Escalation Trial

Author

Heidi Janssen, David W. Dunstan, Paul Mackie, Coralie English, Elizabeth G. Holliday, and Gary Crowfoot

Subjects
medicine.medical_specialty, hypertension, Blood Pressure, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Primary outcome, Internal medicine, Dose escalation, Humans, Medicine, Orthopedics and Sports Medicine, Survivors, Prolonged sitting, Stroke survivor, Secondary prevention, exercise, business.industry, 030229 sport sciences, Confidence interval, Exercise Therapy, Light intensity, Blood pressure, Standing Position, Cardiology, business, secondary prevention
Abstract

Background: Interrupting prolonged sitting acutely lowers blood pressure in nonstroke populations. However, the dose–response effect in stroke survivors is unknown. The authors investigated different doses of light-intensity standing exercises that interrupt prolonged sitting and reduce blood pressure immediately and over 24 hours in stroke survivors. Methods: Within-participant, laboratory-based, dose escalation trial. Conditions (8 h) were prolonged sitting and 2 experimental conditions of standing exercises with increasing frequency (3 cohorts, 2 × 5 min to 6 × 5 min). The primary outcome is the mean systolic blood pressure. Results: Twenty-nine stroke survivors (aged 66 [12] y) participated. Frequent bouts of standing exercises lowered the mean systolic blood pressure following the 4 × 5-minute (−2.1 mm Hg; 95% confidence interval [CI], −3.6 to −0.6) and 6 × 5-minute conditions (−2.3 mm Hg; 95% CI, −4.2 to −0.5) compared with prolonged sitting. Diastolic blood pressure was lowered following the 6 × 5-minute condition (−1.4 mm Hg; 95% CI, −2.7 to −0.2). The 24-hour systolic blood pressure increased following the 2 × 5-minute condition (6.9 mm Hg; 95% CI, 3.1 to 10.6). Conclusions: Interrupting prolonged sitting with more frequent bouts of standing exercises lowers systolic and diastolic blood pressure in stroke survivors. However, reductions may only be short term, and investigations on sustained effects are warranted.

Published
2021

43. Theory-Informed Models: Application to Nursing Practice

Author

Kathleen Shannon Dorcy, Annette English, Jill Williams, Diane Heye, Sherry Joseph, Linda Ross, Amelia Sherinski, and Phuong Huynh

Subjects
Washington, Nursing practice, Value (ethics), 2019-20 coronavirus outbreak, Medical education, business.industry, Theoretical models, Clinical Practice, Oncology nursing, Alliance, Humans, General Earth and Planetary Sciences, Relevance (law), Medicine, Models, Nursing, business, General Environmental Science
Abstract

The processes for review and confirmation of a theoretical model, its translation into current clinical practice, and the evaluation of outcomes will be presented. The authors' experience at the Seattle Cancer Care Alliance in Washington illustrates the value and relevance of theoretical models in oncology care.

Published
2021

44. Vitamin D supplementation and risk of falling: outcomes from the randomized, placebo‐controlled D‐Health Trial

Author

Peter R. Ebeling, Rachel E. Neale, Dallas R. English, Hai Pham, Donald S. A. McLeod, David C. Whiteman, Rachel O'Connell, Mary Waterhouse, Bruce K. Armstrong, Gunter Hartel, Emma Sanguineti, Catherine Baxter, Briony Duarte Romero, Michael G. Kimlin, Alison Venn, Penelope M. Webb, and Jolieke C. van der Pols

Subjects
medicine.medical_specialty, Diseases of the musculoskeletal system, Placebo, law.invention, Randomized controlled trial, law, Physiology (medical), Internal medicine, Bolus dose, Vitamin D and neurology, medicine, Humans, Orthopedics and Sports Medicine, Vitamin D, Aged, Osteomalacia, business.industry, QM1-695, Australia, Original Articles, Vitamins, Odds ratio, medicine.disease, Confidence interval, Clinical trial, RC925-935, Dietary Supplements, Human anatomy, Original Article, Accidental Falls, Falls, business, Body mass index
Abstract

Background Falls cause considerable morbidity and mortality in older people. It is unclear how vitamin D supplementation affects falls risk, particularly when taken at high doses. We sought to determine whether monthly high‐dose vitamin D supplementation reduces risk and incidence of falls. Methods We used data from the randomized, double‐blind, placebo‐controlled D‐Health Trial conducted in Australia. Between February 2014 and May 2015, 21 315 participants aged 60–84 years were randomized (1:1) to monthly doses of either 60 000 IU of colecalciferol or placebo for a maximum of 5 years. People who reported a history of osteomalacia, sarcoidosis, hyperparathyroidism, hypercalcaemia or kidney stones or who were taking >500 IU/day supplementary vitamin D were ineligible. Each year, we collected blood samples from ~450 randomly sampled participants from each trial arm and measured 25‐hydroxyvitamin D [25(OH)D]. Falls, a prespecified tertiary outcome, were ascertained using annual surveys and, for a subset of participants, 3‐month falls diaries. The primary outcome for this analysis was any fall in the month before completing an annual survey. As part of our process to maintain blinding, we used random samples of participants (surveys, n = 16 000; diaries, n = 2400), with equal numbers per group. Participants with no outcome data were excluded. Following an intention‐to‐treat approach, we analysed outcomes using logistic, ordinal and negative binomial regression. Registration: Australian New Zealand Clinical Trials Registry (ACTRN12613000743763); registered 4 July 2013. Results Mean treatment duration was 4.3 years (standard deviation [SD] = 1.4 years). Mean serum 25(OH)D concentrations during the trial were 114.8 (SD 30.3) nmol/L and 77.5 (SD 25.2) nmol/L in the vitamin D and placebo groups, respectively. Survey and diary analytic sets included 15 416 and 2200 participants, respectively; approximately half were randomized to vitamin D (surveys: 50.1%; diaries: 50.4%). Vitamin D had no effect on falling in the past month (odds ratio [OR] 1.02, 95% confidence interval [CI] 0.95–1.10). There was an interaction with body mass index (BMI) (P‐interaction = 0.001); vitamin D increased risk in participants with BMI

Published
2021

45. Reliability of Field Assessment Stroke Triage for Emergency Destination Scale Use by Paramedics: Mobile Stroke Unit First-Year Experience

Author

Diogo C Haussen, Katleen Chester, Olivia Morgan, Nicolas Bianchi, Michael Frankel, Nirav Bhatt, Stephen W. English, Digvijaya Navalkele, Nicholas J. Janocko, Raul G Nogueira, and Carol Fleming

Subjects
Male, Patient Transfer, Emergency Medical Services, Telemedicine, medicine.medical_specialty, Time Factors, Intraclass correlation, Allied Health Personnel, Interquartile range, Emergency medical services, Humans, Medicine, Stroke, Reliability (statistics), Aged, Advanced and Specialized Nursing, business.industry, Reproducibility of Results, Middle Aged, medicine.disease, Triage, Emergency Medical Technicians, Inter-rater reliability, Emergency medicine, Female, Neurology (clinical), Tomography, X-Ray Computed, Cardiology and Cardiovascular Medicine, business, Mobile Health Units
Abstract

Background and Purpose: Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale is a helpful tool to triage patients with stroke in the field. However, data on its reliability in the prehospital setting are lacking. We aim to test the reliability of FAST-ED scale when used by paramedics in a mobile stroke unit covering a metropolitan area. Methods: As part of standard operating mobile stroke unit procedures, paramedics initially evaluated patients. If the event characterized a stroke alert, the FAST-ED score was determined by the paramedic upon patient contact (in-person) and then independently by a vascular neurologist (VN) immediately after paramedic evaluation (remotely/telemedicine). This allowed testing of the interrater agreement of the FAST-ED scoring performance between on-site prehospital providers and remotely located VN. Results: Of a total of 238 patients transported in the first 15 months of the mobile stroke unit’s activity, 173 were included in this study. Median age was 63 (interquartile range, 55.5–75) years and 52.6% were females. A final diagnosis of ischemic stroke was made in 71 (41%), transient ischemic attack in 26 (15%), intracranial hemorrhage in 15 (9%), whereas 61 (35%) patients were stroke mimics. The FAST-ED scores matched perfectly among paramedics and VN in 97 (56%) instances, while there was 0 to 1-point difference in 158 (91.3%), 0 to 2-point difference in 171 (98.8%), and 3 or more point difference in 2 (1.1%) patients. The intraclass correlation between VN and paramedic FAST-ED scores showed excellent reliability, intraclass correlation coefficient 0.94 (95% CI, 0.92–0.96; P Conclusions: We demonstrate excellent reliability of FAST-ED scale performed by paramedics when compared with VN, indicating that it can be accurately performed by paramedics in the prehospital setting.

Published
2021

46. Clinical, Immunological, and Virological SARS-CoV-2 Phenotypes in Obese and Nonobese Military Health System Beneficiaries

Author

Stephanie A Richard, David A Lindholm, Nusrat J. Epsi, Caroline English, Nikhil Huprikar, Mark P Simons, Timothy Burgess, Anthony C. Fries, Cristian Madar, Christopher J Colombo, Ryan C. Maves, Anuradha Ganesan, Simon Pollett, Rhonda E Colombo, Eric D Laing, David R. Tribble, Eugene V. Millar, Katrin Mende, Sharon Chi, Tahaniyat Lalani, Christopher C. Broder, Brian K. Agan, and Derek T Larson

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Odds ratio, Anthropometry, Logistic regression, medicine.disease, Obesity, Confidence interval, Infectious Diseases, Oxygen therapy, Internal medicine, medicine, Immunology and Allergy, business, Body mass index, Viral load
Abstract

Background The mechanisms underlying the association between obesity and coronavirus disease 2019 (COVID-19) severity remain unclear. After verifying that obesity was a correlate of severe COVID-19 in US Military Health System (MHS) beneficiaries, we compared immunological and virological phenotypes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in both obese and nonobese participants. Methods COVID-19–infected MHS beneficiaries were enrolled, and anthropometric, clinical, and demographic data were collected. We compared the SARS-CoV-2 peak IgG humoral response and reverse-transcription polymerase chain reaction viral load in obese and nonobese patients, stratified by hospitalization, utilizing logistic regression models. Results Data from 511 COVID-19 patients were analyzed, among whom 24% were obese and 14% severely obese. Obesity was independently associated with hospitalization (adjusted odds ratio [aOR], 1.91; 95% confidence interval [CI], 1.15–3.18) and need for oxygen therapy (aOR, 3.39; 95% CI, 1.61–7.11). In outpatients, severely obese had a log10 (1.89) higher nucleocapsid (N1) genome equivalents (GE)/reaction and log10 (2.62) higher N2 GE/reaction than nonobese (P = 0.03 and P < .001, respectively). We noted a correlation between body mass index and peak anti-spike protein IgG in inpatients and outpatients (coefficient = 5.48, P < .001). Conclusions Obesity is a strong correlate of COVID-19 severity in MHS beneficiaries. These findings offer new pathophysiological insights into the relationship between obesity and COVID-19 severity.

Published
2021

47. Quality Improvement in Neurology

Author

Jeffrey B. English, Alexander Rae-Grant, Neeta Garg, Tracie A. Caller, Amanda Montague, Elizabeth Page, Michael J. Olek, Iris Vanessa Marin Collazo, Barbara Giesser, Amy Bennett, Adam G. Kelly, and Lilyana Amezcua

Subjects
medicine.medical_specialty, Quality management, Neurology, business.industry, Multiple sclerosis, Quality measurement, Disease, medicine.disease, Quality of life (healthcare), Environmental health, Health care, Medicine, Neurology (clinical), business, Set (psychology)
Abstract

Multiple sclerosis (MS) is a disabling immune-mediated disease of the CNS and considered one of the health conditions with the highest annual spending growth paid by both public and private insurance.1 Health care spending in the United States for MS was reported as $13.9 billion in 2016.1 The estimated cumulated (over 10 years) prevalence of MS among adults in the United States in 2010 was approximately 727,000.2 In 2017, that number was substantially higher, approximately 914,000.2,3 The prevalence is higher among women, with a female: male ratio of 2.8.2 Improving high-quality care for these patients can lead to improved outcomes, reduced spending, and better quality of life.

Published
2021

48. Manuscript: Defining Quality Standards for Intensive Home Based Treatment Programs for Youth with Serious Emotional Disorders

Author

Kelly English, Joseph L. Woolston, Eric J. Bruns, Philip H. Benjamin, Richard Shepler, Hunter Pluckebaum, Marianne A. Kellogg, and Michelle D. Zabel

Subjects
050103 clinical psychology, medicine.medical_specialty, Quality management, Adolescent, Quality Assurance, Health Care, media_common.quotation_subject, Delphi method, Health informatics, Health administration, medicine, Humans, 0501 psychology and cognitive sciences, Quality (business), Affective Symptoms, Child, media_common, business.industry, Health Policy, Public health, 05 social sciences, Public Health, Environmental and Occupational Health, Behavioral health, Public relations, Workforce development, Home Care Services, Quality, Mental health, Treatment, Psychiatry and Mental health, Fidelity, Original Article, Pshychiatric Mental Health, business, 050104 developmental & child psychology
Abstract

Intensive Home Based Treatment (IHBT) is a critical component of the continuum of community-based behavioral healthcare for youth with serious emotional disorder (SED) and their families. Yet despite being used nationwide at costs of over $100 million annually in some states, a well-vetted, research-based set of quality standards for IHBT has yet to be developed. The current project aimed to define program and practice standards for IHBT, drawing upon literature review, expert interviews, and a systematic Delphi process engaging over 80 participants, including IHBT developers, experts in evidence-based youth mental health, youth and family advocates, IHBT providers, and state policymakers. After two rounds of quantitative and qualitative input, adequate consensus was achieved on 32 IHBT Program Standards and 43 IHBT Practice Standards. These standards hold potential for informing efforts such as development of state regulations, provider contracts, memoranda of agreement, and training and workforce development initiatives. Translation of the quality standards into measurement strategies holds potential for providing a method of continuous quality improvement across multiple levels as well as use in research on IBHT.

Published
2021

49. Utilization of Asynchronous and Synchronous Teledermatology in a Large Health Care System During the COVID-19 Pandemic

Author

Andrew Liu, Laura K. Ferris, Joseph C. English, Louis D. Falo, Maria R. Evankovich, Autumn Moorhead, Rashek Kazi, and Rebecca Liu

Subjects
Telemedicine, Teledermatology, medicine.medical_specialty, 020205 medical informatics, Health Informatics, Dermatology, 02 engineering and technology, Telehealth, Skin Diseases, symbols.namesake, Health Information Management, Health care, 0202 electrical engineering, electronic engineering, information engineering, Humans, Medicine, Medical prescription, Medical diagnosis, Pandemics, Retrospective Studies, SARS-CoV-2, business.industry, COVID-19, General Medicine, Bonferroni correction, Asynchronous communication, Emergency medicine, symbols, business, Delivery of Health Care
Abstract

Background: Teledermatology offers an opportunity to continually deliver care during the coronavirus disease 2019 pandemic. Objective: To provide quantitative data about the use of teledermatology. Methods: Retrospective analysis of teledermatology consultations was performed from March 16 to May 1, 2020. The number/type of encounters, differences in diagnoses, and prescriptions between asynchronous and synchronous teledermatology visits were analyzed. Results: A total of 951 visits (36.2%) were asynchronous whereas 1,672 visits (63.8%) were synchronous. Only 131 (

Published
2021

50. Short- and Long-term Health Care Resource Utilization and Costs Following Intracerebral Hemorrhage

Author

Peter Tanuseputro, Manish M. Sood, Bram Rochwerg, Dar Dowlatshahi, Shane W. English, Robert Talarico, Shannon M. Fernando, Danial Qureshi, Damon C. Scales, Victoria A. McCredie, Eric E. Smith, Kwadwo Kyeremanteng, and Michael D. Hill

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Total cost, medicine.medical_treatment, MEDLINE, Interquartile range, Outcome Assessment, Health Care, Health care, Humans, Medicine, health care economics and organizations, Aged, Cerebral Hemorrhage, Retrospective Studies, Aged, 80 and over, Ontario, Mechanical ventilation, Intracerebral hemorrhage, business.industry, Anticoagulants, Retrospective cohort study, Health Care Costs, Middle Aged, medicine.disease, Respiration, Artificial, Emergency medicine, Female, Neurology (clinical), business, Facilities and Services Utilization, Resource utilization
Abstract

ObjectiveWe sought to evaluate the short- and long-term resource use and costs associated with intracerebral hemorrhage (ICH) taken from an entire population. We in addition sought to evaluate the association of oral anticoagulation (OAC) and health care costs.MethodsThis was a retrospective cohort study of adult patients (≥18 years) with ICH in the entire population of Ontario, Canada (2009–2017). We captured outcomes through linkage to health administrative databases. We used generalized linear models to identify factors associated with total cost. Analysis of OAC use was limited to patients ≥66 years of age. The primary outcome was total 1-year direct health care costs in 2020 US dollars.ResultsAmong 16,248 individuals with ICH (mean age 71.2 years, male 52.3%), 1-year mortality was 46.0%, and 24.2% required mechanical ventilation. The median total 1-year cost was $26,886 (interquartile range [IQR] $9,641–$62,907) with costs for those who died in hospital of $7,268 (IQR $4,031–$14,966) vs $44,969 (IQR $20,264–$82,414, p < 0.001) for survivors to discharge. OAC use (analysis limited to individuals ≥66 years old) was associated with higher total 1-year costs (cost ratio 1.06 [95% confidence interval 1.01–1.11]). Total 1-year costs for the entire cohort exceeded $120 million per year over the study period.ConclusionsICH is associated with significant health care costs, and the median cost of a patient with ICH is roughly 10 times the median inpatient cost in Ontario. Costs were higher among survivors than deceased patients. OAC use is independently associated with increased costs. To maximize cost-effectiveness, future therapies for ICH must aim to reduce disability, not only improve mortality.

Published
2021

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