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Pregnancies in women with Turner syndrome: a retrospective multicentre UK study

Authors :
Lucy MacKiliop
Catriona Bhagra
Lowri A. Allen
Aisling Carroll
Katherine von Klemperer
Fionnuala M. McAuliffe
R. Katie Morris
Paul Timmons
Catherine Head
Asha Shetty
Farah Siddiqui
Aidan P Bolger
D. Aled Rees
Matilde Calanchini
Claire Alexander
Philip J. Steer
Samantha Bonner
Linden Stocker
Rachael James
Dawn Adamson
Lydia Simpson
Eleanor Joy
Lucy Hudsmith
Niamh Keating
Sarah Vause
Mandeep K. Kaler
Helen E Turner
Ruth T Casey
Kate English
Aarthi R Mohan
Stephanie L. Curtis
Matthew Cauldwell
Source :
BJOG: An International Journal of Obstetrics & Gynaecology. 129:796-803
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Objective\ud To determine the characteristics and outcomes of pregnancy in women with Turner Syndrome\ud \ud Design\ud Retrospective 20-year cohort study (2000-2020)\ud \ud Setting\ud 16 tertiary referral maternity units in the UK\ud \ud Population or Sample\ud 81 women with Turner syndrome who became pregnant\ud \ud Methods\ud Retrospective chart analysis\ud \ud Main Outcome Measures\ud Mode of conception, pregnancy outcomes\ud \ud Results\ud We obtained data on 127 pregnancies in 81 women with a Turner phenotype. All non-spontaneous pregnancies (54/127 (42.5%)) were by egg donation. Only 9/31 (29%) of pregnancies in women with karyotype 45,X were spontaneous, compared with 53/66 (80.3%) with mosaic karyotype 45,X/46,XX (p

Details

ISSN :
14710528 and 14700328
Volume :
129
Database :
OpenAIRE
Journal :
BJOG: An International Journal of Obstetrics & Gynaecology
Accession number :
edsair.doi.dedup.....155219c5da869a832a329da3af6c4e29
Full Text :
https://doi.org/10.1111/1471-0528.17025