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Your search keyword '"Debra L. Sager"' showing total 4 results
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4 results on '"Debra L. Sager"'

1. Myopic Shift at 10-Year Follow-up in the Infant Aphakia Treatment Study

Author

David R. Weakley, Azhar Nizam, Deborah K. VanderVeen, M. Edward Wilson, Stacy Kruger, Scott R. Lambert, Lindreth DuBois, Buddy Russell, Michael Ward, Robert Hardy, Eileen Birch, Ken Cheng, Richard Hertle, Craig Kollman, Marshalyn Yeargin-Allsopp, Cyd McDowell, Donald F. Everett, Qi Long, Michael Lynn, Betsy Bridgman, Marianne Celano, Julia Cleveland, George Cotsonis, Nana Freret, Lu Lu, Neeta Shenvi, Seegar Swanson, Thandeka Tutu-Gxashe, Carey Drews-Botsch, Claudio Busettini, Samuel Hayley, Joost Felius, Allen Beck, Edward G. Buckley, David A. Plager, Carolyn Drews-Botsch, E. Eugenie Hartmann, Eugenie Hartmann, Anna K. Carrigan, Clara Edwards, Margaret Bozic, Theresa A. Mansfield, Kathryn Bisceglia Miller, Stephen P. Christiansen, Erick D. Bothun, Ann Holleschau, Jason Jedlicka, Patricia Winters, Jacob Lang, Elias I. Traboulsi, Susan Crowe, Heather Hasley Cimino, Kimberly G. Yen, Maria Castanes, Alma Sanchez, Shirley York, Amy K. Hutchinson, Lindreth Dubois, Rachel Robb, Marla J. Shainberg, David T. Wheeler, Ann U. Stout, Paula Rauch, Kimberly Beaudet, Pam Berg, Sharon F. Freedman, Lois Duncan, B.W. Phillips, John T. Petrowski, David Morrison, Sandy Owings, Ron Biernacki, Christine Franklin, Daniel E. Neely, Michele Whitaker, Donna Bates, Dana Donaldson, Charlotte Tibi, Susan Vega, David R. Stager, Clare Dias, Debra L. Sager, Todd Brantley, and Faruk Orge

Subjects
Ophthalmology, Myopia, Humans, Infant, Aphakia, Postcataract, Cataract Extraction, Aphakia, Follow-Up Studies
Published
2021

2. Stereopsis results at 4.5 years of age in the infant aphakia treatment study

Author

E. Eugenie Hartmann, Ann U. Stout, Michael J. Lynn, Kimberly G. Yen, Stacey J. Kruger, Scott R. Lambert, Lindreth DuBois, Michael Lynn, Betsy Bridgman, Marianne Celano, Julia Cleveland, George Cotsonis, Carey Drews-Botsch, Nana Freret, Lu Lu, Seegar Swanson, Thandeka Tutu-Gxashe, Anna K. Carrigan, Clara Edwards, Claudio Busettini, Samuel Hayley, Eleanor Lewis, Alicia Kindred, Joost Felius, Edward G. Buckley, David A. Plager, M. Edward Wilson, Carolyn Drews-Botsch, Donald F. Everett, Margaret Bozic, Ann Holleschau, Buddy Russell, Michael Ward, Carol Bradham, Deborah K. Vanderveen, Theresa A. Mansfield, Kathryn Bisceglia Miller, Stephen P. Christiansen, Erick D. Bothun, Jason Jedlicka, Patricia Winters, Jacob Lang, Elias I. Traboulsi, Susan Crowe, Heather Hasley Cimino, Faruk Orge, Megin Kwiatkowski, Beth Colon, Maria Castanes, Alma Sanchez, Shirley York, Stacy Malone, Margaret Olfson, David T. Wheeler, Paula Rauch, Kimberly Beaudet, Pam Berg, Amy K. Hutchinson, Rachel Robb, Marla J. Shainberg, Sharon F. Freedman, Lois Duncan, B.W. Phillips, John T. Petrowski, David Morrison, Sandy Owings, Ron Biernacki, Christine Franklin, Daniel E. Neely, Michele Whitaker, Donna Bates, Dana Donaldson, Stacey Kruger, Charlotte Tibi, Susan Vega, David R. Weakley, David R. Stager, Clare Dias, Debra L. Sager, Todd Brantley, Robert Hardy, Eileen Birch, Ken Cheng, Richard Hertle, Craig Kollman, Marshalyn Yeargin-Allsopp, Cyd McDowell, and Allen Beck

Subjects
Male, medicine.medical_specialty, Visual acuity, genetic structures, Contact Lenses, medicine.medical_treatment, Visual Acuity, Intraocular lens, Aphakia, Article, law.invention, Cataracts, Randomized controlled trial, Lens Implantation, Intraocular, law, Ophthalmology, medicine, Humans, Prospective Studies, Prospective cohort study, Depth Perception, business.industry, medicine.disease, eye diseases, Contact lens, Stereopsis, Child, Preschool, Multivariate Analysis, Female, sense organs, medicine.symptom, business
Abstract

Purpose To determine whether stereopsis of infants treated for monocular cataracts varies with the type of optical correction used. Design Randomized prospective clinical trial. Methods The Infant Aphakia Treatment Study randomized 114 patients with unilateral cataracts at age 1–7 months to either primary intraocular lens (IOL) or contact lens correction. At 4.5 years of age a masked examiner assessed stereopsis on these patients using 3 different tests: (1) Frisby; (2) Randot Preschool; and (3) Titmus Fly. Results Twenty-eight patients (25%) had a positive response to at least 1 of the stereopsis tests. There was no statistically significant difference in stereopsis between the 2 treatment groups: Frisby (contact lens, 6 [11%]; IOL, 7 [13%]; P = .99), Randot (contact lens, 3 [6%]; IOL, 1 [2%]; P = .62), or Titmus (contact lens, 8 [15%]; IOL, 13 [23%]; P = .34). The median age at surgery for patients with stereopsis was younger than for those without stereopsis (1.2 vs 2.4 months; P = .002). The median visual acuity for patients with stereopsis was better than for those without stereopsis (20/40 vs 20/252; P = .0003). Conclusion The type of optical correction did not influence stereopsis outcomes. However, 2 other factors did: age at surgery and visual acuity in the treated eye at age 4.5 years. Early surgery for unilateral congenital cataract and the presence of visual acuity better than or equal to 20/40 appear to be more important than the type of initial optical correction used for the development of stereopsis.

Published
2014

3. The infant aphakia treatment study: design and clinical measures at enrollment

Author

Lois Duncan, Marianne Celano, Theresa A. Mansfield, Michael J. Lynn, Ann U. Stout, E. Eugenie Hartmann, Rachel Reeves, Daniel E. Neely, Lindreth DuBois, Donna Bates, Heather Hasley Cimino, Elias I. Traboulsi, Julia Cleveland, Alma Sanchez, Betsy Bridgman, Paula Rauch, Susan Vega, Debra L. Sager, Marshalyn Yeargin-Allsopp, George Cotsonis, Scott R. Lambert, Thandeka Tutu-Gxashe, Joost Felius, Dana Donaldson, Deborah K. VanderVeen, Edward G. Buckley, Shirley York, M. Edward Wilson, Ann M. Holleschau, David T. Wheeler, Marla J. Shainberg, Maria Castanes, Sharon F. Freedman, Amy K. Hutchinson, Claudio Busettini, Carolyn Drews-Botsch, Clare Dias, Margaret Bozic, Kimberly Beaudet, Patricia Winters, Craig Kollman, Sandy Owings, David R. Weakley, Nana Freret, Todd Brantley, Robert J. Hardy, B.W. Phillips, Lu Lu, Kimberly G. Yen, Michael A. Ward, Buddy Russell, Clara Edwards, Donald F. Everett, Charlotte Tibi, Erick D. Bothun, Jason Jedlicka, Stacey J. Kruger, David R. Stager, Richard W. Hertle, Kenneth P. Cheng, Cindy Bachman, Susan Crowe, David A. Plager, Pam Berg, Eileen E. Birch, Michele Whitaker, Ron Biernacki, Kathryn Bisceglia Miller, Stephen P. Christiansen, Seegar Swanson, John T. Petrowski, David G. Morrison, Allen D. Beck, Christine Franklin, and Samuel Hayley

Subjects
Male, medicine.medical_specialty, Refractive error, Visual acuity, genetic structures, Eye Movements, Pseudophakia, Contact Lenses, medicine.medical_treatment, Visual Acuity, Aphakia, Postcataract, Cataract Extraction, Aphakia, Cataract, Article, law.invention, Randomized controlled trial, Cataracts, Lens Implantation, Intraocular, law, Ophthalmology, medicine, Humans, business.industry, Infant, Cataract surgery, medicine.disease, Refractive Errors, eye diseases, Surgery, Contact lens, Eyeglasses, Treatment Outcome, Research Design, Congenital cataracts, Female, sense organs, medicine.symptom, business, Follow-Up Studies
Abstract

Objective To compare the use of contact lenses and intraocular lenses (IOLs) for the optical correction of unilateral aphakia during infancy. Methods In a randomized, multicenter (12 sites) clinical trial, 114 infants with unilateral congenital cataracts were assigned to undergo cataract surgery with or without IOL implantation. Children randomized to IOL treatment had their residual refractive error corrected with spectacles. Children randomized to no IOL treatment had their aphakia treated with a contact lens. Main outcome measures Grating acuity at 12 months of age and HOTV visual acuity at 4 1/2 years of age. Application to clinical practice This study should determine whether either treatment for an infant with a visually significant unilateral congenital cataract results in a better visual outcome. Results Enrollment began December 23, 2004, and was completed January 16, 2009. The median age at the time of cataract surgery was 1.8 months. Fifty patients were 4 to 6 weeks of age at the time of enrollment; 32, 7 weeks to 3 months of age; and the remaining 32, more than 3 to less than 7 months of age. Fifty-seven children were randomized to each treatment group. Eyes with cataracts had shorter axial lengths and steeper corneas on average than the fellow eyes. Conclusions The optimal optical treatment of aphakia in infants is unknown. However, the Infant Aphakia Treatment Study was designed to provide empirical evidence of whether optical treatment with an IOL or a contact lens after unilateral cataract surgery during infancy is associated with a better visual outcome.

Published
2010

4. Complications in the First 5 Years Following Cataract Surgery in Infants With and Without Intraocular Lens Implantation in the Infant Aphakia Treatment Study

Author

David A. Plager, Michael J. Lynn, Edward G. Buckley, M. Edward Wilson, Scott R. Lambert, Lindreth DuBois, Michael Lynn, Carolyn Drews-Botsch, E. Eugenie Hartmann, Donald F. Everett, Buddy Russell, Michael Ward, Robert Hardy, Eileen Birch, Ken Cheng, Richard Hertle, Craig Kollman, Marshalyn Yeargin-Allsopp, Cyd McDowell, Betsy Bridgman, Marianne Celano, Julia Cleveland, George Cotsonis, Carey Drews-Botsch, Nana Freret, Lu Lu, Seegar Swanson, Thandeka Tutu-Gxashe, Claudio Busettini, Samuel Hayley, Joost Felius, Allen Beck, Anna K. Carrigan, Clara Edwards, Margaret Bozic, Deborah K. Vanderveen, Theresa A. Mansfield, Kathryn Bisceglia Miller, Stephen P. Christiansen, Erick D. Bothun, Ann Holleschau, Jason Jedlicka, Patricia Winters, Jacob Lang, Elias I. Traboulsi, Susan Crowe, Heather Hasley Cimino, Kimberly G. Yen, Maria Castanes, Alma Sanchez, Shirley York, Amy K. Hutchinson, Lindreth Dubois, Rachel Robb, Marla J. Shainberg, David T. Wheeler, Ann U. Stout, Paula Rauch, Kimberly Beaudet, Pam Berg, Sharon F. Freedman, Lois Duncan, B.W. Phillips, John T. Petrowski, David Morrison, Sandy Owings, Ron Biernacki, Christine Franklin, Daniel E. Neely, Michele Whitaker, Donna Bates, Dana Donaldson, Stacey Kruger, Charlotte Tibi, Susan Vega, David R. Weakley, David R. Stager, Clare Dias, Debra L. Sager, Todd Brantley, and Faruk Orge

Subjects
medicine.medical_specialty, Visual acuity, genetic structures, business.industry, medicine.medical_treatment, Intraocular lens, Cataract surgery, medicine.disease, Aphakia, Article, eye diseases, law.invention, Surgery, Contact lens, Ophthalmology, Randomized controlled trial, law, Anesthesia, Medicine, sense organs, medicine.symptom, business, Prospective cohort study, Adverse effect
Abstract

Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective randomized clinical trial. Methods A total of 114 infants were enrolled in the Infant Aphakia Treatment Study, a randomized, multi-center (12) clinical trial comparing the treatment of unilateral aphakia in patients under 7 months of age with a primary IOL implant or contact lens. The rate, character, and severity of intraoperative complications, adverse events, and additional intraocular surgeries during the first 5 postoperative years in the 2 groups were examined. Results There were more patients with intraoperative complications (28% vs 11%, P = .031), adverse events (81% vs 56%, P = .008), and more additional intraocular surgeries (72% vs 16%, P Conclusion The increased rate of complications, adverse events, and additional intraocular surgeries associated with IOL implantation in infants

Published
2014
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