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There are various references to sensitization to beryllium in the literature. Since introducing a patch testing series for patients with suspected sensitization to metals, we have found 3 cases of sensitization to beryllium. Of these 3 cases, we regard the first 2 having relevant sensitization. Beryllium chloride (1% pet) was positive in 3 patients and negative in 150 controls. [ABSTRACT FROM AUTHOR]

The article presents a case of a 62-year-old woman with a suspected allergic reaction to a denture. Forty-five days after first using her new denture, the patient complained of irritation in the denture-bearing area. One month later, the symptoms worsened but improved when she did not wear the denture for two days. Patch tests showed a positive reaction to camphoroquinone, a photoinitiator in commercial visible-light-cured dental composite resins.

This article presents two case studies related to contact dermatitis from lincomycin and spectinomycin in chicken vaccinators. A 27-year-old female had worked as a chicken vaccinator for 4 years. In June 1989, 2 months after using lincomycin for the first time, her fingertips and dorsa of the fingers of both hands began to itch, more so on the right hand. In 5 days, the clinical picture worsened. Erythema and papules appeared on the dorsum of both hands and in 2 days spread to the forearms. Pruritus increased greatly. She stopped work and on treatment with topical corticosteroids and oral antibistamines, her skin cleared within 10 days. Another 27-year-old female had worked on the same farm for 2 years. Previous to this, she had worked as an ironer. She had an allergy to imitation jewellery since the age of 15 years.

This article discusses a case study related to contact dermatitis from nickel and cobalt in a contact lens cleaning solution. An 18-year-old female with intolerance to imitation jewellery since that age had worn semi-soft contact lenses for 2 years and had used various products to clear them. The last product she used was composed of hydroxymethyl cellulose, polypropylene glycol, hydroxymethyl aminomethane, thimerosal and distilled water. At presentation, the patient had slight erythema and edema on the upper and lower eyelids, with intense conjunctivitis and erythematus papules on the cheeks and perinasal and eyebrow regions.

Allergic contact dermatitis and photoallergic contact dermatitis from NSAID, especially ketoprofen, have both been reported, most recently mainly from Europe and the Mediterranean area. The majority of cases of dermatitis from ketoprofen are photoallergic, those of allergic contact dermatitis being less frequent. The case under study has two particular features. It is a case of allergic contact dermatitis in which, in spite of the possible solar influence, a patch test without irradiation was strongly positive. The intense clinical picture completely spared the area of skin initially atrophied by excessive application of a potent topical steroid. This phenomenon could not be further substantiated as the patient refused a biopsy of the apparently unaffected atrophic area. Otherwise, electron microscopy for Langerhans cells could have been performed.

This article presents 3 case reports related to contact dermatitis to thiourea. The first case is of a 41-year-old housewife who suffered from tendinitis of the right elbow, which was treated with an ointment. Redness and itching appeared in the area of application. The second case is of a 39-year-old housewife who had an operation on the right knee for arthritis 10 months previously. A bone implant was grafted from the ankle and held in place by 2 stainless steel clips. Due to intolerance and rejection, the clips were removed after six months.

A 38-year old male, electrical engineer, with an asthmatic son had a hobby of fishing. For one year, he has had bright red, itchy lesions of the fingertips of both hands, except the right index and ring fingers, with occasional blisters which desquamated and fissured. He knew the cause only wanted therapeutic advice. He suspected some of the 7 different maggots he used as bait. Standard patch tests were negative. Previous open tests with the 7 crushed maggots had not elicited any reaction.

This article presents case reports on the study of several children who had contact dermatitis. The study was conducted on 1023 children. Three patients were positive to fragrance mix, cinnamic alcohol and eugenol. Six patients were positive to PPDA, sulphanilamide and caine mix. Thirteen patients were positive to thiomersal and metallic mercury. Five patients were positive to thiomersal, mercury metallic, ammoniated mercury, phenylmercuric acetate, phenylmercuric nitrate and mercury bichloride. Sixty-two children with test reactions to nickel, cobalt or both had a previous history of metal intolerance. Thirty-one children with reactions to fragrance mix, cinnamic alcohol, eugenol, mercury compounds, balsam had a previous history related to the use of cosmetics.

An analysis has been made of patch test reactions in patients at two Departments of Dermatology in Spain, in relation to sensitization to cosmetics. During the period of the study fifty-eight thousand, one hundred and twenty-eight patients attended the two departments; of these five thousand, five hundred and thirty nine were patch tested and four hundred and sixty were considered to have positive tests related to cosmetic. However, only hundred and eighty seven patients were suspected of having a contact dermatitis from cosmetics. The sex distribution of the four hundred and sixty patients was three hundred and sixty women and hundred men.

The article presents a case showing contact dermatitis, which is caused due to nasal sprays and amyl nitrite. Imidazole chlorhydrate is a sympathomimetic agent with marked alpha-adrenergic activity used as a vasoconstrictor with rapid and prolonged action to relieve nasal congestion caused by rhinitis and sinusitis. There is no other reference to this substance as a contact sensitizer. Amyl nitrite is one group of volatile nitrites whose nature, uses and adverse reactions have been described by various scientists.

The article discusses about diaminodiphenylmethane which was used as standard patch tests by authors who are members of Spanish Contact Dermatitis Research Group G.E.I.D.C. Among 2,490 patients who were tested, 212 were found to be positive to diaminodiphenylmethane. The article discusses concomitant reactions of diaminodiphenylmethane and other para-group allergens. As per the statistical report that was published by the G.E.I.D.C., it is found to be the potent allergen. So, authors had planned to investigate sources of sensitization to this potent allergen.

The article focuses on medical references to the allergenic capacity of copper when it is present in the intrauterine contraceptive devices (IUCD). Four patients with identical clinical picture were diagnosed. These patients with the standard Spanish Contact Dermatitis Research Group were tested with patch test series and also with copper sulfate and barium sulfate. There have been references to metal device sensitization in dental prostheses, surgical prostheses, pacemakers and acupuncture needles. IUCD copper sensitization is another example of this special pattern of allergic contact dermatitis.

The article presents five cases of allergic sensitization to pyrrolnitrine, a new antifungal agent obtained from Pseudomonas pyrrocine. The International Contact Dermatitis Research Group series was negative in all the patients. It also includes the patients' history, clinical features, and results of patch testing.

The article focuses on tow cases of allergic reactions to treatment with some of the drives forms of vitamin K. Vitamin K is available commercially in two forms, natural and synthetic. The cases of occupational sensitization to one synthetic derivative, the vitamin K3 sodium bisulfite is discusses here. A women was working in a pharmaceutical laboratory where she was in contact with many drugs of varied composition. She developed dyshidrosiform and vesicular exudative lesions on her index and middle finger of the right hand.

This article focuses on the sensitization to cinnamic aldehyde in toothpaste. For the last 2 year, almost 15 patients have been observed suffering from cheilitis, fissures of lips and stomatitis. Four of the patients wore dental prosthesis. Patch tests with the standard allergen series were recommend. For seven of the patients patch test was found to be negative. Two patients were found to be positive for cinnamic aldehyde and Ultrabrite toothpaste. In the course of years it was also found that eight patients with contact dermatitis of the of the face showed positive test reactions to various cosmetics.

The article focuses on low irritancy of 2-day occlusive patch test with calcipotriol cream. To assess the irritant capacity of calcipotriol, the researchers patch tested it in 100 volunteers among patients. Vitamin D and its analogues have successfully been used in the topical treatments of psoriasis. All references that can be found to vitamin D , that report its topical tolerance refer to psoriatic patients. In a group of 786 such patients who applied calcipotriol, the most frequent adverse reactions were skin irritation and facial/scalp irritation.

This article presents information on a case study related contact dermatitis from eugenol in mouthwash. A 52-year-old woman with a long history intolerance to imitation jewellery, had experienced numerous dental problems, resulting in the replacement of almost all her natural teeth with prosthesis, originally fixed, but since replaced with removable ones of mixed composition. The patient reported that. since the dental problems first began, she had used various different mouthwashes. Approximately 6 weeks after beginning to use it, she noticed a burning sensation in the jugal mucosa and on the tongue which after 3 days became inflamed.

Allergic contact dermatitis in metalworkers has increasingly been reported in recent years. Although many different compounds added to cutting oils can be sensitizers, biocides are the most common, most are water-soluble and very stable. In Spain. the most widely used are the Grotans and the Biobans. The results of patch testing in patients with occupational contact dermatitis from the metalworking industry in 2 contact dermatitis clinics in Barcelona, Spain during 1990 and 1991 are reported in the article.

Captan is widely used both as a Fungicide and as a bacteriostat in cosmetics and toiletries, including shampoos. It has been described as an experimental sensitizer in humans, a sensitizer in pesticides, and a photosensitizer in shampoos. The article presents a case of 21-year-old hairdresser who developed intense pruritus on the hands, forearms, face and neck. She was treated with oral antihistamine and topical corticosteroid. The sensitization was considered to captan as having arisen from hairdressing products, most probably due to its use as a bacteriostat in shampoos.

A 30-year-old Caucasian teacher presented with a 13-month history of eyelid eczema, coinciding with the use of an eye pencil. Topical corticosteroids produced improvement, but relapse occurred when she reused the eye pencil. Her mother was allergic to penicillin and nickel and her father to chromate and cobalt. On patch testing, she was positive to nickel in the standard series and to the eye pencil as is but not to any of its individual constituents supplied by the manufacturer, nor to a cosmetics series.

A 13 year old boy developed itchy maculo-rythematous lesions on the dorsum of the feet and toes, with hyperkeratotic lesions on the soles, continuing in outbreaks depending on treatment, always worsening in the summer. He always wore sports shoes, trainers or deck shoes. It was concluded that the patient had a footwear dermatitis caused exclusively by rubber accelerators, and that the initial patch testing had caused an angry back but not an angry thigh.

A case has been reported that a 49-year old housewife began to itch on the dorsum and soles of both feet, followed by the appearance of initially papulo-erythematous lesions at the same sites and on the legs. These lesions later became purpuric, while remaining itchy. On ceasing to wear the boots and with adequate treatment, eczematous lesions disappeared after a few days, the purpuric lesions took 6 weeks to disappear, 3 months later, the patient wore the boots again and the lesions reoccurred after 4 days, on the dorsum and soles of both feet.

This article focuses on the high incidence of sensitization to turpentine in Spain. The subject was reviewed by the GEIDC, which concluded the Canadian turpentine used for their standard series should be changed to Scandinavian turpentine. The reasons for the change were the following: First, the Scandinavian turpentine is more frequently used in Spanish industries; Second, there is a high percentage of a-pinene in Canadian turpentine and only 47.88% in Scandinavian; Third, there is a low proportion of limonene in turpentine and 5.98% in Scandinavian turpentine.

This article focuses on a study related to the leukoderma from hydroquinone. Two case, both female, are reported in the article, where there was a previous history of having used a commercial preparation containing hydroquinone monomethylether 10%. The history did not state whether lesions disappeared after using this preparation. Patch tests to reproduce achromic lesions were not carried out in either case. Another patient, a female aged 27 years, who used a bleaching cream for facial melasma, and developed leukoderma on cheeks and forehead. On ceasing the use of the bleaching cream, lesions of the patient disappeared after one month.

This article focuses on a study related to the dermatitis from nickel eyelash curler. In the present case, a 38-year-old female with no previous eczema or atopic background, developed red, scaling, itchy lesions on eyelids near eyelashes. They only disappeared when she was suffering from hepatitis. Patch test showed only positive to nickel and cobalt chloride. As she used an eyelash curler that is completely metallic except for the part which touches the eyelid whish is made of black rubber.

The article presents a case of dermatitis from Para-Aminobenzoic Acid (PABA) and hydroquinone. The patient was a 34 year old woman who developed contact dermatitis of the face and neck in the year1982. She was atopic and had previously been treated for scabies. She also had chloasma. She was patch tested with the standard series, some cosmetics and components of a special bleaching cream used for the treatment of chloasma. The only positive reaction was to hydroquinone. In June 1982, the patient returned with the same clinical picture. She tested positive for para-aminobenzoic acid and sulisobenzone in a water-alcohol base.

A 17-year-old lady is presented with a polymorphic acneiform eruption of special distribution on the face; it had been present for two years. Several treatments prescribed during this time by different physicians failed to cure it. Patch test was conducted on the patient. The results of patch test standard allergen series were negative. The patient was recommended to change the metallic frame for a plastic one and received conventional treatment for acne. After 21 days she was seen again and found to be completely cured.

A 30-year-old man presented with psoriasis of the scalp, elbows and sacral region. Treatment with salicylic acid provoked an immediate eczematous and exudative reaction at all the treated sites, most evident on the scalp. Suspecting some kind of topical sensitization. The patient was patch tested. Surprisingly, the patient showed positive reactions to all the tests, with the exception of turpentine. Bisphenol A and creosote, the vehicle for which is lanette wax for the other allergens the vehicle was yellow soft paraffin.