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Start Over Descriptor "CACAO" Topic academic medical centers Topic therapeutics
4 results on '"CACAO"'

1. Central Arterial Hemodynamic Effects of Dark Chocolate Ingestion in Young Healthy People: A Randomized and Controlled Trial.

Author

Pereira, T., Maldonado, J., Laranjeiro, M., Coutinho, R., Cardoso, E., Andrade, I., and Conde, J.

Subjects
*ENDOTHELIUM physiology, *CACAO, *ACADEMIC medical centers, *ANALYSIS of variance, *ANTIOXIDANTS, *CHI-squared test, *FISHER exact test, *HEMODYNAMICS, *LONGITUDINAL method, *NUTRITION, *PREVENTIVE health services, *STATISTICS, *T-test (Statistics), *DATA analysis, *RANDOMIZED controlled trials, *DATA analysis software, *FLAVONOLS, *DESCRIPTIVE statistics, *THERAPEUTICS
Abstract

Introduction. The aim of this study was to assess the vascular benefits of dark chocolate in healthy and young individuals. Methods. A randomized and controlled trial was carried out involving 60 healthy volunteers, randomized into two groups: control group (CG; n = 30) and intervention group (IG; n = 30). The IG ingested a daily dosage of 10 g of dark chocolate (>75% cocoa) for a month. Blood pressure (BP), flow-mediated dilation (FMD), arterial stiffness index (ASI), aortic pulse wave velocity (PWV), and pulse wave analysis (PWA) were assessed at baseline and one week after the one-month intervention period. Results. Arterial function improved after intervention in the IG, with PWV decreasing from 6.13 ± 0.41 m/s to 5.83 ± 0.53 m/s (P = 0.02), with no significant differences observed in the CG. A significant decrease in ASI (0.16 ± 0.01 to 0.13 ± 0.01; P < 0.001) and AiX (-15.88 ± 10.75 to -22.57 ± 11.16; P = 0.07) was also depicted for the IG. Endothelial function improved in the IG, with the FMD increasing 9.31% after the 1-month intervention (P < 0.001), with no significant variation in the CG. Conclusion. The daily ingestion of 10 g dark chocolate (>75% cocoa) during a month significantly improves vascular function in young and healthy individuals. [ABSTRACT FROM AUTHOR]

Published
2014
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2. Consumption of High-Polyphenol Dark Chocolate Improves Endothelial Function in Individuals with Stage 1 Hypertension and Excess Body Weight.

Author

de Paula Nogueira, Lívia, Paranhos Knibel, Marcela, Gonçalves Torres, Márcia Regina Simas, Nogueira Neto, José Firmino, and Felipe Sanjuliani, Antonio

Subjects
*CARDIOVASCULAR disease diagnosis, *CACAO, *ACADEMIC medical centers, *BEHAVIOR modification, *BLOOD pressure measurement, *BODY weight, *DIET, *ENDOTHELIUM, *HEALTH behavior, *HOMEOSTASIS, *HYPERTENSION, *LIPOPROTEINS, *NUTRITION, *PHENOLS, *PLASTIC surgery, *DATA analysis, *DESCRIPTIVE statistics, *THERAPEUTICS
Abstract

Background. Hypertension and excess body weight are important risk factors for endothelial dysfunction. Recent evidence suggests that high-polyphenol dark chocolate improves endothelial function and lowers blood pressure. This study aimed to evaluate the association of chocolate 70% cocoa intake with metabolic profile, oxidative stress, inflammation, blood pressure, and endothelial function in stage 1 hypertensives with excess body weight. Methods. Intervention clinical trial includes 22 stage 1 hypertensives without previous antihypertensive treatment, aged 18 to 60 years and presents a body mass index between 25.0 and 34.9 kg/m2. All participants were instructed to consume 50 g of chocolate 70% cocoa/day (2135 mg polyphenols) for 4 weeks. Endothelial function was evaluated by peripheral artery tonometry using Endo-PAT 2000 (Itamar Medical). Results. Twenty participants (10 men) completed the study. Comparison of pre-post intervention revealed that (1) there were no significant changes in anthropometric parameters, percentage body fat, glucose metabolism, lipid profile, biomarkers of inflammation, adhesion molecules, oxidized LDL, and blood pressure; (2) the assessment of endothelial function through the reactive hyperemia index showed a significant increase: 1.94 ± 0.18 to 2.22 ± 0.08, P = 0.01. Conclusion.In individuals with stage 1 hypertension and excess body weight, highpolyphenol dark chocolate improves endothelial function. [ABSTRACT FROM AUTHOR]

Published
2012
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3. Is there cadmium in your cocoa?

Subjects
*ACADEMIC medical centers, *CACAO, *CADMIUM, *HEALTH, *THERAPEUTICS
Abstract

The article offers information on the health benefits associated with eating chocolates and also mentions the advantages and disadvantages of presence of cadmium in chocolates. It mentions a study conducted by American Journal of Clinical Nutrition, which investigates the role of eating flavanol-enriched cocoa powder in improving measures of cognitive functioning in older people.

Published
2015

4. Should you work chocolate into your diet?

Subjects
*FLAVONOIDS, *PREVENTION of heart diseases, *ACADEMIC medical centers, *CACAO, *CARBOHYDRATES, *DIET, *HEALTH, *LOW density lipoproteins, *NUTRITIONAL requirements, *THOUGHT & thinking, *WEIGHT gain, *SATURATED fatty acids, *THERAPEUTICS
Abstract

The article discusses the health benefits of cocoa flavanols that are naturally-occurring bioactive compounds found in the cocoa beans of the fruit produced by the cacao tree. It mentions that flavanols are type of plant nutrient found in several foods and drinks such as tea, red wine, and blueberries. It notes that flavanols in cocoa can help lower blood pressure, improve blood flow to the brain, and heart, and fight cell damage.

Published
2015

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