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Your search keyword '"Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes]"' showing total 2 results
Start Over Author "Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes]" Topic 3. good health
2 results on '"Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes]"'

1. Decreased iron burden in overweight C282Y homozygous women: Putative role of increased hepcidin production

Author

Romain Desgrippes, Edouard Bardou-Jacquet, Fabrice Lainé, Michèle Perrin, Martine Ropert, Ghislain Manet, Yves Deugnier, Caroline Jezequel, Jeff Morcet, Service des Maladies de l'Appareil Digestif [CHU Rennes], CHU Pontchaillou [Rennes], fer et métabolismes, Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Fer et Métabolismes, Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Service des Maladies de l'Appareil Digestif [CHU Rennes], CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes], Laboratoire de biochimie spécialisée, Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Foie, métabolismes et cancer, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Liver Unit of Rennes, the nursing staff, Beatrice Leclerc, Centre de, Lecoupe-Grainville, Marie, Service des Maladies de l'Appareil Digestif, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Service des Maladies de l'Appareil Digestif, Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes], and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
Male, Comorbidity, Overweight, Body Mass Index, Cohort Studies, 0302 clinical medicine, Phlebotomy, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, biology, Homozygote, Transferrin, Middle Aged, 3. Good health, 030220 oncology & carcinogenesis, Female, Hemochromatosis, medicine.symptom, Adult, medicine.medical_specialty, Iron, 03 medical and health sciences, Insulin resistance, Hepcidins, Hepcidin, Internal medicine, medicine, Humans, Hemochromatosis Protein, Retrospective Studies, 030304 developmental biology, Hepatology, Transferrin saturation, business.industry, Histocompatibility Antigens Class I, Membrane Proteins, nutritional and metabolic diseases, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Endocrinology, chemistry, Case-Control Studies, Ferritins, Multivariate Analysis, biology.protein, Insulin Resistance, business, Body mass index, Antimicrobial Cationic Peptides
Abstract

International audience; An excess of visceral adipose tissue could be involved as a modulator of the penetrance of HFE hemochromatosis since fat mass is associated with overexpression of hepcidin and low transferrin saturation was found to be associated with being overweight in women. This study was aimed at assessing the relationship between body mass index (BMI), a surrogate marker of insulin resistance, and iron burden in HFE hemochromatosis. In all, 877 patients from a cohort of C282Y homozygotes were included in the study when BMI at diagnosis and amount of iron removed (AIR) by phlebotomy were available. No relationship between AIR and BMI was found in men, whereas 15.1% (52/345) of women with AIR

Published
2013

2. Thyroid-stimulating hormone receptor antibody assays: recommendation for correct interpretation of results in Graves disease

Author

Catherine Massart, Michèle d’Herbomez, Unité Laboratoire CIC, Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle biologie, Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes], Pôle de Biologie Pathologie Génétique [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle biologie, and Université de Rennes (UR)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]-CHU Pontchaillou [Rennes]

Subjects
endocrine system, medicine.medical_specialty, endocrine system diseases, Graves' disease, Clinical Biochemistry, 030209 endocrinology & metabolism, Trab, MESH: Graves Disease, Gastroenterology, Thyrotropin receptor, MESH: Calibration, MESH: Receptors, Thyrotropin, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, MESH: Practice Guidelines as Topic, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Internal medicine, medicine, Humans, ComputingMilieux_MISCELLANEOUS, Immunoassay, MESH: Humans, biology, business.industry, Biochemistry (medical), Thyroid, Receptors, Thyrotropin, Reference Standards, medicine.disease, Graves Disease, 3. Good health, medicine.anatomical_structure, Hormone receptor, Calibration, Practice Guidelines as Topic, Immunology, 030221 ophthalmology & optometry, biology.protein, Etiology, MESH: Reference Standards, Antibody, business, MESH: Immunoassay, MESH: Immunoglobulins, Thyroid-Stimulating, Immunoglobulins, Thyroid-Stimulating
Abstract

To the Editor: In Graves disease, the clinical uses of thyrotropin receptor [thyroid-stimulating hormone receptor (TSH-R)1] antibody (TRAb) measurements have been reported in the Thyroid Guidelines of the American Thyroid Association (1). First, TRAb measurements are used to investigate the etiology of hyperthyroidism when the diagnosis is not clinically obvious; second, a declining TRAb concentration during long-term antithyroid drug therapy is suggestive of remission, although TRAb measurements can be misleading in 25% of such patients; third, TRAb is used in the follow-up of pregnant women with a history or recent onset of Graves …

Published
2013

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