1. Serum CA 19-9 Level is Correlated to the Clinical Characteristics and Chronic Complications of Patients Newly Diagnosed with Type 2 Diabetes Mellitus
- Author
-
Limei Cui, Xiaomin Zheng, Cuiping Liu, Bin Li, Jing Tao, Naqiang Lv, and Yehua Yan
- Subjects
0301 basic medicine ,Adult ,Blood Glucose ,Male ,medicine.medical_specialty ,endocrine system diseases ,CA-19-9 Antigen ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Newly diagnosed ,Logistic regression ,Gastroenterology ,Diabetic nephropathy ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Risk Factors ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Diabetic Nephropathies ,Aged ,Glycated Hemoglobin ,Diabetic Retinopathy ,business.industry ,Type 2 Diabetes Mellitus ,General Medicine ,Diabetic retinopathy ,Middle Aged ,medicine.disease ,030104 developmental biology ,Quartile ,Diabetes Mellitus, Type 2 ,CA19-9 ,Female ,Hemoglobin ,business ,Biomarkers ,Diabetic Angiopathies - Abstract
Aim This study investigated the relation of serum carbohydrate antigen 199 (CA 19–9) levels to the clinical characteristics and chronic complications of patients newly diagnosed with type 2 diabetes mellitus (T2DM).Methods A total of 371 patients newly diagnosed with T2DM and 133 healthy people with consecutively matched age were compared. The 371 patients with T2DM were divided into four groups by quartiles based on their serum CA 19–9 levels, in which clinical characteristics and chronic complications, such as diabetic retinopathy (DR), diabetic nephropathy, and macrovascular complications were compared. Logistic regression analysis was used to evaluate the risk factors of DR.Results Among the 371 patients newly diagnosed with T2DM, 60 had elevated CA 19–9 levels (16.17%). The frequencies of elevated serum CA 19–9 were 24.39% (30 of 123) for females and 12.10% (30 of 248) for males, in which the values for females were higher than those for males (PConclusions Serum CA 19–9 levels were correlated with HbA1c and DR in patients newly diagnosed with T2DM. The elevated serum CA 19–9 levels, high FC-P, and FBG levels were important risk factors for DR in patients newly diagnosed with T2DM.
- Published
- 2019