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Serum CA 19-9 Level is Correlated to the Clinical Characteristics and Chronic Complications of Patients Newly Diagnosed with Type 2 Diabetes Mellitus
- Source :
- Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 129(8)
- Publication Year :
- 2019
-
Abstract
- Aim This study investigated the relation of serum carbohydrate antigen 199 (CA 19–9) levels to the clinical characteristics and chronic complications of patients newly diagnosed with type 2 diabetes mellitus (T2DM).Methods A total of 371 patients newly diagnosed with T2DM and 133 healthy people with consecutively matched age were compared. The 371 patients with T2DM were divided into four groups by quartiles based on their serum CA 19–9 levels, in which clinical characteristics and chronic complications, such as diabetic retinopathy (DR), diabetic nephropathy, and macrovascular complications were compared. Logistic regression analysis was used to evaluate the risk factors of DR.Results Among the 371 patients newly diagnosed with T2DM, 60 had elevated CA 19–9 levels (16.17%). The frequencies of elevated serum CA 19–9 were 24.39% (30 of 123) for females and 12.10% (30 of 248) for males, in which the values for females were higher than those for males (PConclusions Serum CA 19–9 levels were correlated with HbA1c and DR in patients newly diagnosed with T2DM. The elevated serum CA 19–9 levels, high FC-P, and FBG levels were important risk factors for DR in patients newly diagnosed with T2DM.
- Subjects :
- 0301 basic medicine
Adult
Blood Glucose
Male
medicine.medical_specialty
endocrine system diseases
CA-19-9 Antigen
Endocrinology, Diabetes and Metabolism
030209 endocrinology & metabolism
Newly diagnosed
Logistic regression
Gastroenterology
Diabetic nephropathy
03 medical and health sciences
0302 clinical medicine
Endocrinology
Risk Factors
Internal medicine
Internal Medicine
medicine
Humans
Diabetic Nephropathies
Aged
Glycated Hemoglobin
Diabetic Retinopathy
business.industry
Type 2 Diabetes Mellitus
General Medicine
Diabetic retinopathy
Middle Aged
medicine.disease
030104 developmental biology
Quartile
Diabetes Mellitus, Type 2
CA19-9
Female
Hemoglobin
business
Biomarkers
Diabetic Angiopathies
Subjects
Details
- ISSN :
- 14393646
- Volume :
- 129
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
- Accession number :
- edsair.doi.dedup.....6c16c02d14eb9e8e97c273b809c8e76c