Search

Large pyroelectric and energy harvesting properties have been attracting increasing attentions due to the practical applications in infrared detectors and energy harvesting technologies. Ferroelectric-antiferroelectric (FE-AFE) phase transitions are usually accompanied by a sharp drop in polarization, which will lead to excellent pyroelectric properties and energy harvesting density. Therefore, FE-AFE phase boundary design is an effective strategy to develop new pyroelectric materials. In this paper, Pb(Lu1/2Nb1/2)O3-PbTiO3 (PLN-PT) single crystals with FE-AFE phase transitions were obtained by molten salt growth method. The temperature-induced FE-AFE phase transition was verified by temperature-dependent macrodomain structure, DSC curves and dielectric properties. Obviously, PLN-PT crystals display excellent peak pyroelectric coefficient (∼6.8 μC/(cm2·K)) with a maximum depolarization temperature of 118 °C. Meanwhile, the pyroelectric energy harvesting density is as high as 2.62 J/cm3, which is much higher than other pyroelectric materials. The results reveal that the PLN-PT crystal is a promising candidate for infrared detectors and energy harvesting devices.

Nematic liquid crystals are promising materials for microwave communication owing to their continuous tunability as dielectrics and wide frequency range selection. However,conventional liquid crystals exhibit large dielectric loss and high freezing point, hindering their research and application in microwave communication. in this paper,14 novel liquid crystal polyphenylene compounds with lateral methyl substitute were synthesised. Their structures were characterized by IR, NMR,MS and the elemental analyses. Their mesogenic properties were analyzed by POM and DSC. The dielectric properties in microwave frequencies(10-35 GHz)of eight target compounds (6a,7b,8a~8e) with LC matrix were obtained by extrapolation and perturbation techniques. The results show that i. fluorinated polyphenylene compounds with lateral methyl generally exhibited low melting points (���75��C), ii. compounds with isothiocyanate group yielded high birefringence 0.385-0.441, iii. compounds based on quaterphenyl displayed a wide temperature range of nematic phase, and iv. the maximum dielectric loss of compounds 6e,8c,8e are less than 6.51��10-3,which are better than those of using fluorine replace the methyl group derivative. Therefore, the proposed approach can effectively reduce dielectric loss,reduce the melting temperature, improve the dielectric properties of liquid crystal materials for microwave communication.

The single-atom enzyme (SAE) is a novel type of nanozyme that exhibits extraordinary catalytic activity. Here, we constructed a PEGylated manganese-based SAE (Mn/PSAE) by coordination of single-atom manganese to nitrogen atoms in hollow zeolitic imidazolate frameworks. Mn/PSAE catalyzes the conversion of cellular H2 O2 to . OH through a Fenton-like reaction; it also promotes the decomposition of H2 O2 to O2 and continuously catalyzes the conversion of O2 to cytotoxic . O2 - via oxidase-like activity. The catalytic activity of Mn/PSAE is more pronounced in the weak acidic tumor environment; therefore, these cascade reactions enable the sufficient generation of reactive oxygen species (ROS) and effectively kill tumor cells. The prominent photothermal conversion property of the amorphous carbon can be utilized for photothermal therapy. Hence, Mn/PSAE exhibits significant therapeutic efficacy through tumor microenvironment stimulated generation of multiple ROS and photothermal activity.

Ulva prolifera O.F. Müller (Ulvophyceae, Chlorophyta) is well known as a typical green-tide forming macroalga which has caused the world's largest macroalgal blooms in the Yellow Sea of China. In this study, two full-length γ-carbonic anhydrase (γ-CA) genes (UpγCA1 and UpγCA2) were cloned from U. prolifera. UpγCA1 has three conserved histidine residues, which act as an active site for binding a zinc metal ion. In UpγCA2, two of the three histidine residues were replaced by serine and arginine, respectively. The two γ-CA genes are clustered together with other γ-CAs in Chlorophyta with strong support value (100% bootstrap) in maximum likelihood (ML) phylogenetic tree. Quantitative real-time PCR (qRT-PCR) analysis showed that stressful environmental conditions markedly inhibited transcription levels of these two γ-CA genes. Low pH value (pH 7.5) significantly increased transcription level of UpγCA2 not UpγCA1 at 12 h, whereas high pH value (pH 8.5) significantly inhibited the transcription of these two γ-CA genes at 6 h. These findings enhanced our understanding on transcriptional regulation of γ-CA genes in response to environmental factors in U. prolifera.

In this work, nickel sulfide (Ni3S2) nanowires were directly grown on nickel foam (Ni3S2@NF) via hydrothermal sulfurization of the nickel foam (NF). The Ni3S2@NF electrode exhibited excellent activity for urea oxidation reaction (UOR), which can deliver a current density of 100 mA cm−2 at 0.36 V (vs SCE) for UOR in the electrolyte of 1.0 M NaOH and 0.33 M urea. The Ni3S2@NF electrode also exhibited excellent activity for hydrogen evolution reaction (HER), which shows decent stability and catalytic performance with an overpotential of ˜127 mv at 10 mA cm−2 in 1.0 M NaOH. The excellent catalytic activity for both UOR and HER renders the Ni3S2@NF an efficient bifunctional electrocatalyst for urea-assisted electrolytic hydrogen production. As a result, the two-electrode system assembled with Ni3S2@NF can drive 20 mA cm−2 at a cell voltage of only 1.49 V with excellent longevity.

As a classic transition metal dichalcogenide, WS2 has been synthesized by a variety of methods towards different applications. However, few of them are vertically grown self-templated structures, besides, all the reported WS2 for hydrogen evolution reaction (HER) are in acidic media. Herein, we use a simple method to synthesize a new morphological WS2 triangular nanoplates array through the sulfuration of hydrothermally obtained WO3 nanowires on carbon cloth (WS2TN/CC). The WS2TNs are equilateral triangle with large surface area that grown vertically on carbon fiber. The WS2TN/CC exhibits good catalytic activity and stability as electrocatalyst for HER in acidic media and firstly in both neutral and alkaline media. The overpotential of 196, 150 and 193 mV are needed to afford current density of 10 mA cm−2 in acidic, neutral and alkaline media, respectively.

The targeted delivery of chemotherapeutic drugs is a major challenge in the clinical treatment of cancer. Herein, we constructed a multifunctional DNA nanoplatform as a versatile carrier of the highly potent platinum-based DNA intercalator, 56MESS. In our rational design, 56MESS was efficiently loaded into the double-bundle DNA tetrahedron through intercalation with the DNA duplex. With the integration of a nanobody that both targets and blocks epidermal growth factor receptor (EGFR), the DNA nanocarriers exhibit excellent selectivity for cells with elevated EGFR expression (a common biomarker related to tumor formation) and combined tumor therapy without obvious systemic toxicity. This DNA-based platinum-drug delivery system provides a promising strategy for the treatment of tumors.

In decades of hybrid rice breeding, the combining ability has been successfully used to evaluate excellent parental lines and predict heterosis. However, previous studies for the combining ability mainly focused on cultivated rice and rarely involved wild rice. In this study, for the first time, we identified 20 new quantitative trait loci (QTLs) for the combining ability in wild rice using a North Carolina II mating design. Among them, qGCA1, one of the major QTLs that can significantly improve the general combining ability of the plant height, spikelet number, and yield per plant, was delimited to an interval of about 72 kb on chromosome 1. qSCA8, another major QTL, which can significantly improve the specific combining ability of the seed-setting rate and yield per plant, was located in an interval of about 90 kb on chromosome 8. These QTLs discovered from wild rice will provide new ideas to explain the genetic mechanism of the combining ability and establish the basis for breeding of high-combining-ability rice.

3D NiO nanowalls are homogeneously grown on macroporous nickel foam by a hydrothermal method. The morphology of the NiO nanowalls are characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and the phase structure of NiO nanowalls is characterized by X-ray diffraction (XRD) analysis. The results indicate that the NiO nanowalls are uniformly distributed on the entire nickel foam framework. And ammonia fluoride has significant influence on the height and thickness of NiO nanowalls. With the presence of ammonia fluoride, NiO nanowalls with height of 4.6 (±0.4) μm and thickness around 50 nm were obtained, while the height and thickness decreased to 1.7 (±0.2) μm and around 20 nm without the presence of ammonia fluoride. The NiO nanowalls were used as electrodes for urea oxidation in alkaline condition. The electro-oxidation activity the catalyst is investigated by cyclic voltammetry and potential step chronoamperometry. The electrocatalytic performance of NiO electrodes depends strongly on the sample preparation condition. The 3D NiO nanowalls electrode exhibit excellent electro-oxidation activity towards urea oxidation. The morphology of the electrodes has significant influence on their activity. The current density of 3D NiO nanowalls electrode prepared with NH4F at 0.7 V reached 800 mA cm−2, which was over 4 times than that of sample prepared without NH4F. Moreover, NiO nanowalls prepared with NH4F was more stable than the one prepared without NH4F, which did not show any appreciable morphology change after being used for urea electro-oxidation for 12 h. While the one prepared without NH4F collapsed after used.

Atomic thinness, excellent transport property and gate-tunable band structure of graphene render it a potential electrode material for assembling ultra thin electronic devices. Here, we present back gate field effect transistor based on exfoliated monolayer (ML) ReS2 as channel semiconductor and exfoliated ML-graphene as drain-source electrodes. The G and 2D peaks of ML-graphene stiffen significantly and their intensity ratio increases as well when the graphene is encapsulated between the SiO2/Si substrate and ReS2. Owing to the excellent electron transport properties of the ML-ReS2 and gate-tunable Fermi-level of the underlying ML-graphene, the transistor exhibits on/off current ratio exceeding 106, mobility of ∼1.1 cm2 V−1s−1 and subthreshold swing ∼740 mV per decade. This work indicates that ML-graphene is an excellent electrode material for fabricating atomically thin ReS2 electronic devices.

In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment, their applications are still hampered in therapeutic development due to limitations, such as tumor penetration and high cost of manufacture. Nanobody, a single domain antibody that holds the strong antigen targeting and binding capacity, has demonstrated various advantages relative to antibody. Nanobody is considered as a next-generation of antibody-derived tool in the antigen related recognition and modulation. A number of nanobodies have been developed and evaluated in different stages of clinical trials for cancer treatment. Here we summarized the current progress of nanobody in tumor diagnosis and therapeutics, particularly on the conjugation of nanobody with functional moieties. The nanobody conjugation of diagnostic agents, such as radionuclide and optical tracers, can achieve specific tumor imaging. The nanobody-drug conjugates can enhance the therapeutic efficacy of anti-tumor drugs and reduce the adverse effects. The decoration of nanobody on nanodrug delivery systems can further improve the drug targeting to specific tumors. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease.

Mineral elements play an extremely important role in human health, and are worthy of study in rice grain. Wild rice, as an important gene pool for rice improvement in grain yield, disease and pest resistance as well as mineral elements. In this study, we identified 28 novel quantitative trait loci (QTL) for content of six mineral elements in wild rice Oryza longistaminata. Interestingly, these QTL exhibited significant co-location, including qSe1/qCd1 on chromosome 1, qCd4.2/qHg4 on chromosome 4, qFe5.2/qZn5.2 on chromosome 5, qFe9.2/qZn9.3/qAs9 on chromosome 9 and qCd10/qHg10/qAs10 on chromosome 10. Among them, qSe1/qCd1, one of the co-localizing sites that can significantly improve the Se content while reducing the Cd content, was delimited to an interval about 53.8 Kb on chromosome 1. qFe5.2/qZn5.2, another co-localizing sites which can significantly improve the Fe and Zn content, was located in a region about 26.2 Kb on chromosome 5. These QTL derived from wild rice Oryza longistaminata will provide new insights into the genetic mechanism of mineral element accumulation, and establish the basis for subsequent gene cloning and mineral element composition improvement in rice grains.

Cu(i) binds to the N-terminal metal binding domain (MBD) of hCTR1 and induces its conformational change, which promotes the interaction of the MBD with cell membranes. The membrane interaction was confirmed in living cells. This process could be the first step to initiate the cellular uptake of copper ions by hCTR1.

All-inorganic halide perovskites have attracted significant attention because of their excellent photoelectric performance. However, several remaining challenges, including large-scale synthesis, strict limitations on the experimental conditions, and material stability, limit their practical application. In this study, we propose a simple ligand-assisted supersaturated recrystallization (LASR) procedure in order to prepare perovskite-related plum-pudding-like Cs4PbBr6/CsPbBr3 microcrystals (MCs) on a large scale and at room temperature. The LASR approach was proved to rely on the selection of an appropriate antisolvent. The synthesized Cs4PbBr6/CsPbBr3 MCs exhibit strong green emission at 520 nm with a narrow full-width at half-maximum (FWHM) value of 20 nm originating from the CsPbBr3 nanocrystals (NCs) embedded in the Cs4PbBr6 MCs. Additionally, the environmental stability experiment showed ∼20% PL intensity loss after storage under ambient conditions with 50% relative humidity (RH) for 2 months.

A stable and highly efficient Ag–Ag2S hetero-dendrites (HDs) photocatalyst has been obtained via an extremely facile electrodeposition and subsequently in situ sulfuration route. The SEM and TEM show well-defined uniform dendrites morphology with an average diameter about 30 nm. In addition, the absorption spectra of Ag–Ag2S HDs exhibit strong absorption in both visible and NIR regions. The EIS indicates that the low charge transfer resistance of Ag–Ag2S HDs enhances the photocatalytic activity. The prepared HDs-4 photocatalyst with moderate degree of vulcanization shows excellent activity for degradation the methylene blue (MB) under the sunlight irradiation owing to the suitable ratios of Ag–Ag2S. The enhanced photocatalytic activity could be attributed to the favorable synergistic effects between Ag and Ag2S materials, such as huge extended absorption of solar light, low charge transfer resistance and high electron–hole separation efficiency. Moreover, radical scavenger experiments confirmed that superoxide radicals and holes were the main reactive species for MB degradation. Meanwhile, the Ag–Ag2S HDs displays good photocatalytic stability after being recycled five times.

The reduction in size of field-effect transistors (FETs) comprised of 3D semiconductors is confronted with the issues such as short-channel effects, tunneling effects and thermal dissipation. The emergence of transition metal dichalcogenides (TMDCs) atomic layers has opened up unprecedented opportunities for scaling down of the electronics in view of their unique layered-structure and excellent properties. TMDCs grown directly on high-k dielectric substrates are beneficial for fabricating high-performance FETs. Here, we demonstrate the direct growth of atomically thin MoS2 flakes on high-κ dielectric (HfO2) substrates via a chemical vapor deposition process. The morphology and structure of the as-grown materials were systemically investigated by optical microscope, atomic force microscope, Raman spectroscopy, photoluminescence, transmission electron microscope and X-ray photoelectron spectroscopy. The MoS2 flakes are approximately 5–10 µm in size with polycrystalline monolayer structure. The optical properties of the MoS2 flakes are also found to be substrate-dependent due to optical interference. In addition, back-gate FETs based on the as-grown MoS2 were fabricated and their performance was investigated. The results indicate that the n-type FETs show high on/off current ratio of ~ 106 and a carrier mobility of 9.75 cm2 V−1 s−1.

Narrow band red-emitting A2GeF6:Mn4+ (A = Na, K, Rb, Cs) phosphors were prepared through a two-step precipitation–cation exchange route using a K2MnF6 precursor as the Mn4+ source. The phase purity, morphology, and constituent were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectric spectroscopy (XPS), and electron paramagnetic resonance (EPR) examination. Optical properties were investigated by photoluminescence spectra (PL and PLE) and high-resolution PL. A temperature-dependent PL examination was performed to investigate the electron–phonon coupling emission mechanism of Mn4+ in these alkali fluorogermanates. The PL data show that both ordered distribution and appropriate distance between Mn4+ ions are propitious for enhancement of the emission intensity. A resonance emission enhancement (REE) mechanism has been proposed to explain the intensity increment among these products. These phosphors present bright red emission under blue light (467 nm) illuminatio...

A new series of pyrimidine derivatives containing Schiff bases structure have been synthesized efficiently by modification of the C-2 position of Biginelli 3,4-dihydropyrimidin-2-(1H)-thiones (DHPMs). Their structures have been characterized by IR, 1 H NMR, 13 C NMR, MS spectra and elemental analysis.

Two mitogenomes of Ulva lactuca Linnaeus, one from Florida, USA and another nearly complete mtDNA from Chile, had previously been sequenced. Here, the complete mitogenome of U. lactuca from Shantou...

Ferritin is an iron-storage protein nanocage that is assembled from 24 subunits. The hollow cavity of ferritin enables its encapsulation of various therapeutic agents; therefore, ferritin has been intensively investigated for drug delivery. The use of antibody-ferritin conjugates provides an effective approach for targeted drug delivery. However, the complicated preparation and limited protein stability hamper wide applications of this system. Herein, we designed a novel nanobody-ferritin platform (Nb-Ftn) for targeted drug delivery. The site-specific conjugation between nanobody and ferritin is achieved by transglutaminase-catalyzed protein ligation. This ligation strategy allows the Nb conjugation after drug loading in ferritin, which avoids deactivation of the nanobody under the harsh pH environment required for drug encapsulation. To verify the tumor targeting of this Nb-Ftn platform, a photodynamic reagent, manganese phthalocyanine (MnPc), was loaded into the ferritin cavity, and an anti-EGFR nanobody was conjugated to the surface of the ferritin. The ferritin nanocage can encapsulate about 82 MnPc molecules. This MnPc@Nb-Ftn conjugate can be efficiently internalized by EGFR positive A431 cancer cells, but not by EGFR negative MCF-7 cells. Upon 730 nm laser irradiation, MnPc@Nb-Ftn selectively killed EGFR positive A431 cells by generating reactive oxygen species (ROS), whereas no obvious damage was observed on MCF-7 cells. Given that ferritin can be used for encapsulation of various therapeutic agents, this work provides a strategy for facile construction of nanobody-ferritin for targeted drug delivery.

Bacteriocins from lactic acid bacteria (LAB) arouse general concern in recent years due to their antimicrobial activities against foodborne pathogenic microorganisms. In this study, a novel bacteriocin named as bacteriocin ZFM54, produced by Lactobacillus paracasei ZFM54 isolated from the feces of newborn infant, was purified by a four-step strategy including macroporous resin XAD-16 adsorption chromatography, cation exchange chromatography, Sephadex G-25 gel filtration chromatography, and reverse-phase high-performance liquid chromatography (RP-HPLC). The molecular weight of bacteriocin ZFM54 was 1143.39 Da, the predicted amino acid sequence was ATTLIPPVFGK. Bacteriocin ZFM54 was highly thermostable, active under the acidic condition, sensitive to trypsin and proteinase K, while insensitive to α-amylase, lysozyme, lipase, and ribonuclease A. The bacteriocin possessed a broad-spectrum inhibition against many foodborne pathogens such as Salmonella typhimurium, Micrococcus luteus and Listeria monocytogenes. The mode of action of bacteriocin ZFM54 was related to the pore formation of cell membrane. We further demonstrated that Lipid II, the molecular target of the prototype lantibiotic Nisin, was not the specific target of this bacteriocin. Together, this new bacteriocin has great potential to be used as a biological preservative in the food industry.

Many physical systems can be modeled by a Wiener nonlinear model, which consists of a linear dynamic system followed by a nonlinear static function. This work is concerned with the identification of Wiener systems whose output nonlinear function is assumed to be continuous and invertible. A recursive least squares algorithm is presented based on the auxiliary model identification idea. To solve the difficulty of the information vector including the unmeasurable variables, the unknown terms in the information vector are replaced with their estimates, which are computed through the preceding parameter estimates. Finally, an example is given to support the proposed method.

Metal azolate frameworks (MAFs) as a subfamily of metal-organic frameworks (MOFs) have received much attention in analyzing organic volatiles owing to their remarkable structures. In this work, the headspace solid-phase microextraction (SPME) fiber based on MAF-66 has been fabricated by a layer-by-layer deposition method. To evaluate the performance of the MAF-66-coated fibers, polycyclic aromatic hydrocarbons (PAHs) were tested as analytes with gas chromatography (GC). Relevant experimental parameters were optimized including extraction temperature, extraction time, desorption temperature, desorption time, the stirring rate and salt concentration. Under optimum condition, PAHs including naphthalene, 2-methylnaphthalene, 1-methylnaphthalene, acenaphthylene, acenaphthene, fluorene and phenanthrene were detected with good linear range (0.01–100 μg L−1), low detection limits (0.1–7.5 ng L−1), high enrichment factors (123–3108) and relative standard deviations (RSDs) ranging from 0.23% to 4.2%. Additionally, the fiber exhibited a long lifetime with repetitively used more than 270 times. The proposed method was also successfully applied for the determination of PAHs in environmental samples and food samples.

1,3,5-Trisubstituted 2-pyrazolines were synthesized by the reaction of chalcones with hydrazine in hot ethanol. Their structures were elucidated by 1H NMR, 13C NMR, IR, MS and elemental analysis. The fluorescence spectra were measured in different organic solvents. The emission wavelength is blue shifted with the increase in solvent polarity.

The composite hole injection layers (c-HILs) PTAA/AgNWs/PTAA were introduced into solution-processed blue flexible organic light-emitting diode (FOLED) to improve the hole injection ability, further to lower the driving voltage and enhance the device's performance. By optimizing the of c-HILs, the optimal FOLED has been achieved with a maximum luminance of 6051 cd m-2 at 9 V and a maximum current efficiency of 1.76 cd A-1, which are increased by 45% and 75% compared to that of the control device without c-HILs. Meanwhile, the optimal device presents the low turn-on voltage of 2.7 V at 1 cd m-2 and driving voltage of 6.0 V at 1000 cd m-2, which are decreased by 0.4 V and 1.9 V compared to that of the control device. The electroluminescent (EL) performance enhancement of FOLED is attributed to that the introduction of c-HILs can decrease the hole injection barrier and improve the hole injection ability, which will result in the balanced carrier recombination in emitting layer. Moreover, we analysed the electrical and morphological characteristics of c-HILs, and investigated the mechanism by energy level analysis and impedance spectroscopy.

Lead halide perovskites (LHPs) have received increased attention owing to their intriguing optoelectronic and photonic properties. However, the toxicity of lead and the lack of long-term stability are potential obstacles for the application of LHPs. Herein, the epitaxial synthesis of CsPbX3 (X = Cl, Br, I) perovskite quantum dots (QDs) by surface chemical conversion of Cs2 GeF6 double perovskites with PbX2 (X = Cl, Br, I) is reported. The experimental results show that the surface of the Cs2 GeF6 double perovskites is partially converted into CsPbX3 perovskite QDs and forms a CsPbX3 /Cs2 GeF6 hybrid structure. The theoretical calculations reveal that the CsPbBr3 conversion proceeds at the Cs2 GeF6 edge through sequential growth of multiple PbBr6 4- layers. Through the conversion strategy, luminescent and color-tunable CsPbX3 QDs can be obtained, and these products present high stability against decomposition due to anchoring effects. Moreover, by partially converting red emissive Cs2 GeF6 :Mn4+ to green emissive CsPbBr3 , the CsPbBr3 /Cs2 GeF6 :Mn4+ hybrid can be employed as a low-lead hybrid perovskite phosphor on blue LED chips to produce white light. The leadless CsPbX3 /Cs2 GeF6 hybrid structure with stable photoluminescence opens new paths for the rational design of efficient emission phosphors and may stimulate the design of other functional CsPbX3 /Cs-containing hybrid structures.

In this study, an optical sensor membrane was prepared for sorption and detection of cadmium(II) (Cd(II)) in aqueous solution. A polyanion, poly(sodium 4-styrenesulfonate) (PNaSS), was grafted onto the chloromethylated polysulfone (CMPSF) microporous membrane via surface-initiated ATRP. 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin p-toluenesulfonate (TMPyP) was immobilized onto the PNaSS-grafted polysulfone (PSF-PNaSS) membrane through electrostatic interaction. The TMPyP-functionalized membrane exhibited an enhanced sorption for, and distinct color and spectral response to cadmium(II) (Cd(II)) in aqueous solution. Larger immobilization capacity of TMPyP on the membrane led to stronger sorption for Cd(II), and smaller one made the optical sensor have a faster (in minutes) and more sensitive response to the ion. The detection limit study indicated that the functional membrane with proper amount of TMPyP (

In this report, we describe a method for modifying electrical and optoelectrical properties of CdS nanobelts using low-energy (lower than 10 keV) e-beam irradiation in a scanning electron microscope. The electrical conductivity of the nanobelts was dramatically improved via the irradiation of e-beams. The modified conductivity of the nanobelts depends on the energy of the e-beam; it exhibits a larger photocurrent and higher external quantum efficiency but slower time-response than that before the modification. A possible mechanism about the modification is the increase of electron accumulation (injected electrons) in the nanobelts due to e-beam irradiation. In addition, the optoelectrical modification could be caused by the trapped electrons in the nanobelts and the decrease of contact resistance between the nanobelts and metal electrodes induced by e-beam irradiation. The results of this work are significant for the in situ study of semiconductor nanostructures in the electron microscope. Besides, the method of electrical and optoelectrical modification presented here has potential application in electronics and optoelectronics.