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Abstract To clarify the relationship between GNSS (Global Navigation Satellite System) crustal deformation and the preparation of strong earthquakes in the western Chinese Mainland, a series of methods including velocity field, strain rate field, and strain parameter time series are adopted based on the GNSS observation data from the CMONOC (Crustal Movement Observation Network of China). The abnormal characteristics of crustal deformation movement before the M ≥ 5 earthquakes in the area since 1999 are studied. The corresponding variety of the crustal movement before earthquakes is discussed in combination with the seismogenic structure of earthquakes. The abnormalities of the GNSS velocity field, strain field, and strain parameter time series before earthquakes with different magnitudes are proposed. Finally, the anomaly criterion before medium-strong-large earthquakes in the western Chinese Mainland is proposed according to the GNSS and its combination with the characteristics of geological structure. The results can provide a basis for the forecasting of the trend and location of medium-strong-large earthquakes in the western Chinese Mainland.

The effectiveness of classroom teaching is deeplyinfluenced by teachers' emotional states. Teachers' keen awareness, precise regulation, and efficient management of their own emotions are undoubtedly indispensable core elements for fostering a positive classroom atmosphere. Teachers' emotion regulation constitutes a meticulous processthat integrates value assessmentand strategic deployment, adhering to a progressive logic of identification, screening, and implementation. This process aids teachers in marking their emotional states, activating, and implementing specific emotion regulation strategies. The various stages of teachers' emotion regulation continuously iterate and optimize with the dynamic changes in educational contexts and the passage of time. The value of this implicates that, in terms of instrumental value, it can effectively enhance teaching effectiveness; in terms of intrinsic value, it can bolster teachers' professional well-being; and in terms of communicative value, it can facilitate friendly interactions between teachers and students. Looking ahead, to enhance teachers' emotion regulation abilities, it is imperative to attach great importance to and strengthen emotional education in the pre-service stage, while providing systematic emotional skills training for teachers in the in-service stage. Based on these efforts, continuous exploration into fostering teachers' emotion regulation abilities should be undertaken to establish a long-term development mechanism.

Nitrogen management plays a crucial regulatory role in ensuring rice yield and improving eating quality. In recent years, the significant increase in rice yield has largely relied on the excessive application of nitrogen fertilizers. However, the overuse of nitrogen in rice cultivation has raised widespread concerns due to its contribution to environmental pollution, increased production costs, and risks to human health. At the same time, consumer attention has increasingly shifted towards the eating quality of rice. Therefore, the challenge of improving eating quality while maintaining rice yield has become a key focus of research in this field. This paper reviewed the current domestic and international research on optimizing nitrogen management for rice, with a particular focus on rice yield, starch and protein characteristics, and eating quality. It also analyzed the practical issues associated with nitrogen management in rice production and discussed the prospects of nitrogen management in rice cultivation. This study provided valuable insights for future nitrogen management in rice production, aiming to achieve both high yield and enhanced eating quality.

Escherichia coli, a rod-shaped Gram-negative bacterium, is a significant causative agent of severe clinical bacterial infections. This study aimed to analyze the epidemiology of extended-spectrum β-lactamase (ESBL)-producing mcr-1 -positive E. coli in Shandong, China. We collected 668 non-duplicate ESBL-producing E. coli strains from clinical samples at Shandong Provincial Hospital between January and December 2018, and estimated their minimum inhibitory concentrations (MICs) using a VITEK® 2 compact system and broth microdilution. Next-generation sequencing and bioinformatic analyses identified the mcr-1 gene and other resistance genes in the polymyxin B-resistant strains. The conjugation experiment assessed the horizontal transfer capacity of the mcr-1 gene. Of the strains collected, 24 polymyxin B-resistant strains were isolated with a positivity rate of 3.59% and among the 668 strains, 19 clinical strains carried the mobile colistin resistance gene mcr-1, with a positivity rate of approximately 2.8%. All 19 clinical strains were resistant to ampicillin, cefazolin, ceftriaxone, ciprofloxacin, levofloxacin, and polymyxin B. Seventeen strains successfully transferred the mcr-1 gene into E. coli J53. All transconjugants were resistant to polymyxin B, and carried the drug resistance gene mcr-1. The 19 clinical strains had 14 sequence types (STs), with ST155 (n = 4) being the most common. The whole-genome sequencing results of pECO-POL-29_mcr1 revealed that no ISApl1 insertion sequences were found on either side of the mcr-1 gene. Our study uncovered the molecular epidemiology of mcr-1-carrying ESBL-producing E. coli in the region and suggested horizontal transmission mediated by plasmids as the main mode of mcr-1 transmission.

This article proposes a novel phononic crystal configuration consisting of a through-hole cantilever beam and a mass block, and conducts numerical analysis and experimental verification on the bandgap characteristics of a two-dimensional periodic array plate containing this configuration. The results indicate that there are multiple bending wave band gaps in the proposed structure, and the formation of the bandgap is due to the coupling between elastic waves in the matrix and the resonance characteristics of the local resonant structure. The width of the bandgap is related to the coupling strength. Further research has also found that the proportion of effective mass of the mode is a criterion for determining whether the mode generates a bandgap. At the same time, the regulation of band gaps by the cell constants and geometric parameters of local resonance units was studied. Based on the above research, by improving the original local resonance structure, more abundant bandgap features were obtained, providing a feasible approach for the design of broadband bandgaps. Finally, the vibration transmission rate of the finite period structural plate was obtained through simulation calculations and experiments, and its attenuation frequency band was basically consistent with the bandgap range, indicating that the structure has good low-frequency vibration reduction performance, which has broad engineering application prospects in the field of vibration and noise reduction.

Abstract Background Dachsous cadherin related 1 (DCHS1) is one of calcium-dependent adhesion membrane proteins and is mainly involved in the development of mammalian tissues. There is a lack of more detailed research on the biological function of DCHS1 in pan-cancer. Materials and methods We evaluated the expression, the prognostic value, the diagnostic value and genomic alterations of DCHS1 by using the databases, including TCGA, UALCAN, HPA, GEPIA2.0 and GSCA. We employed the databases of UCSC, TIMER2.0, TISIDB, GSCA to analyze the association between DCHS1 expression and the immune microenvironment, stemness, TMB, MSI and anticancer drug sensitivity. BioGRID, STRING and GEPIA2.0 were used to perform protein interaction and functional enrichment analysis. Real-time quantitative PCR, CCK8, Transwell assay and Western blot were performed to determine the function of DCHS1 in UCEC. Results DCHS1 is differentially expressed in many cancers and its expression is significantly associated with tumor prognosis and diagnosis. DCHS1 expression was significantly correlated with the infiltration of cancer-associated fibroblasts (CAFs), Endothelial cell (ECs), and Hematopoietic stem cell in most cancers. In addition, DCHS1 was significantly associated with sensitivity to many antitumor drugs. Functional enrichment analysis revealed that DCHS1-related proteins were involved in Focal adhesion, Endometrial cancer and Wnt signaling pathway. GSEA results showed that DCHS1 was related to epithelial-mesenchymal transition (EMT) in many cancers. In vitro experiments in UCEC showed that DCHS1 regulated cell proliferation, migration and EMT. Conclusions Our findings indicated that DCHS1 might be a novel prognostic and diagnostic biomarker and immunotherapy target, and plays an important role in the proliferation, migration and EMT in UCEC.

The evaluation of design results plays a crucial role in the development of design. This study presents a design work evaluation system for design education that assists design instructors in conducting objective evaluations. An automatic design evaluation model based on convolutional neural networks has been established, which enables intelligent evaluation of student design works. During the evaluation process, the CAM is obtained. Simultaneously, an eye-tracking experiment was designed to collect gaze data and generate eye-tracking heat maps. By comparing the heat maps with CAM, an attempt was made to explore the correlation between the focus of the evaluation’s attention on human design evaluation and the CNN intelligent evaluation. The experimental results indicate that there is some certain correlation between humans and CNN in terms of the key points they focus on when conducting an evaluation. However, there are significant differences in background observation. The research results demonstrate that the intelligent evaluation model of CNN can automatically evaluate product design works and effectively classify and predict design product images. The comparison shows a correlation between artificial intelligence and the subjective evaluation of human eyes in evaluation strategy. Introducing artificial intelligence into the field of design evaluation for education has a strong potential to promote the development of design education.

Abstract Background Quantitative analysis of retinal nerve fibers is important for the diagnosis and treatment of optic nerve diseases. Peripapillary retinal nerve fiber layer (RNFL) cross-sectional area may give a more accurate quantitative assessment of retinal nerve fibers than RNFL thickness but there have been no previous reports of the peripapillary RNFL cross-sectional area or other parameters. The purpose of the current study was to determine peripapillary RNFL cross-sectional area and its association with other factors in an adult Chinese population. Methods RNFL cross-sectional area was measured during peripapillary circular optical coherence tomography (OCT) scan with a diameter of 12° centered on the optic disc. Correlation between RNFL cross-sectional area and other parameters was evaluated by linear regression analysis in a cross-sectional study of an adult Chinese population. Results A total of 2404 eyes from 2404 subjects were examined. Multivariate linear regression analysis showed that larger RNFL cross-sectional area correlated with younger age (p

Objective To evaluate the project-based management in reducing acupressure medical adhesive-associated skin injury in patients with chronic gastritis, and provide a reliable basis for clinical practice. Methods Take the tendency score matching method, 1: 1 matching to find control. Finally, 235 cases of chronic gastritis were selected from the Department of Gastroenterology from October 2021 to March 2022 as the intervention group (2215 times of application) for project management; From October 2020 to March 2021, 235 patients with chronic gastritis were used as the control group (2215 times of application) and were managed by traditional mode, comparing the quality management results of the specific work, associated skin damage, and pain scores at removal of the acupressure applied in both groups. Results By adopting the project-based management model, the overall target achievement rate reached 93. 27% and the overall progress rate reached 63. 95%, which was better than the target and achieved the expected results, in which the quality monitoring results of the intervention group were significantly higher than those of the control group (P

Objective Through the problem-oriented clinical syndrome differentiation thinking, the Xianghu dispelling-cold cake moxibustion was adopted in the treatment of spleen-stomach deficiency cold type epigastric pain, and related nursing measures were summarized. Methods The clinical data of 106 hospitalized patients with epigastric pain from September 2021 to August 2022, were selected and randomized into 2 groups. 53 cases in the control group received routine care, and 53 cases in the intervention group received Xianghu dispelling-cold cake moxibustion treatment on the basis of the control group. The symptom scores, time to pain relief, patient satisfaction and treatment compliance were observed and compared between two groups. Results the Traditional Chinese Medicine syndrome scores in both groups decreased after intervention, and Traditional Chinese Medicine syndrome scores in the intervention group decreased more significantly than those in the control group (P

In this study, we are concerned with the existence and exponential stability issue of a delayed differential neoclassical growth model with discontinuous control strategy. By employing the Filippov’s theory and dichotomy theory, together with the Lyapunov functional method, novel criteria on existence and exponential stability are established for the addressed model. The established theoretical results extend and supplement the related results in the existing literature. Moreover, a simulation example is presented to verify the practicability of the proposed results.

Microblogs are currently one of the most well-liked social platforms in China, and sentiment analysis of microblog texts can help further analyze the realization of their media value; however, the current task of sentiment analysis based on microblog information suffers from low accuracy due to the large size and high redundancy of microblog data, a microblog sentiment analysis method using Bidirectional Encoder Representation from Transformers (BERT)–Text Convolutional Neural Network (TextCNN)–Bidirectional Gate Recurrent Unit (BiGRU)–Multihead-Attention model in Spark big data environment is proposed. First, the Chinese pre-trained language model BERT is used to convert the input data into dynamic character-level word vectors; then, TextCNN is used to effectively obtain local features such as keywords and pool the filtered features; then, BiGRU is introduced to quickly capture more comprehensive semantic information; finally, a multi-headed attention mechanism is implemented to emphasize the most significant features in order to accomplish the sentiment classification of microblog information task precisely. By comparing the existing advanced models, the proposed model demonstrates an improvement of at least 4.99% and 0.05 in accuracy and F1-score evaluation indexes, respectively. This enhancement significantly enhances the accuracy of microblog sentiment analysis tasks and aids pertinent authorities in comprehending the inclination of individual’s attitude toward hot topics. Furthermore, it facilitates a prompt prediction of topic trends, enabling them to guide public opinion accordingly.

The composition of phenolics extracted from unripe banana flesh was identified using ultra-high performance liquid chromatography coupled with Q-Exactive Orbitrap mass spectrometry (UPLC-Q-Exactive Orbitrap-MS), and the inhibitory effects of banana polyphenols on α-amylase and α-glucosidase were estimated in vitro. In total, 28 compounds were identified, including 21 polyphenols such as esculetin, hyperoside, and kaempferol-3-O-glucoside, 2 organic acids, 3 ellagitannin metabolites, vanillin and coumarin. In addition, dimethyl ellagic acid and urolithin A were the major chromatographic peaks. Banana polyphenols exhibited excellent inhibitory effects on both α-amylase and α-glucosidase with half maximal inhibitory concentration (IC50) of 0.53 mg/mL and 35.76 µg/mL, respectively. At concentrations of 1.0 mg/mL and 160 µg/mL, the inhibition rates of α-amylase activity and α-glucosidase were (76.25 ± 3.79)% and (92.54 ± 0.69)%, respectively. Therefore, polyphenols may be one of the active ingredients contributing to the anti-hypoglycemic effect of unripe bananas.

Voltage instability, power imbalance, and unreliability are caused mainly by equipment failure in the distribution system, so it is important to accurately and quickly assess the status of distribution network equipment. However, it is challenging to detect equipment failures, the traditional XGBoost algorithm is unsuitable because some evaluation indices are incompetent to quantify. To address these issues, we propose a fast evaluation method for the state of electrical distribution equipment based on fuzzy decision-making. Firstly, key indices are selected from the multi-source equipment information. Secondly, this paper constructs the mapping between key indices and equipment status scores by combining the fuzzy iterative method and the XGBoost algorithm. Finally, the proposed assessment model is confirmed by using the distribution transformers as an example. The result shows that the proposed multi-source information assessment method can quickly and accurately determine the operation status of electrical distribution equipment, and the proposed method has better accuracy than the traditional method.

The ovarian surface epithelium (OSE) is a single layer of squamous-to-cuboidal epithelial cells that experience repetitive ovulatory rupture and subsequent repair. However, the characteristics of human immortalized ovarian surface epithelial cells (IOSE80) remain elusive. This study aims to determine whether IOSE80 cells have the characteristics of stem cell proliferation and multilineage differentiation and their application in regenerative medicine. IOSE80 cells are sequenced by high-throughput transcriptome analysis, and 5 sets of public data are used to compare the differences between IOSE80 cells and bone marrow mesenchymal stem cells, pluripotent stem cells, and oocytes in transcriptome profiling. The IOSE80 cells present a cobblestone-like monolayer and express the epithelial cell marker KRT18; the stem cell markers IFITM3, ALDH1A1, and VIM; lowly express stem cell marker LGR5 and germ cell markers DDX4 and DAZL. In addition, the GO terms “regulation of stem cell proliferation”, “epithelial cell proliferation”, etc., are significantly enriched (P

The advancement of unloading technology in combine harvesting is crucial for the intelligent development of agricultural machinery. Accurately measuring material pile height in transport vehicles is essential, as uneven accumulation can lead to spillage and voids, reducing loading efficiency. Relying solely on manual observation for measuring stack height can decrease harvesting efficiency and pose safety risks due to driver distraction. This research applies binocular vision to agricultural harvesting, proposing a novel method that uses a stereo matching algorithm to measure material pile height during harvesting. By comparing distance measurements taken in both empty and loaded states, the method determines stack height. A linear regression model processes the stack height data, enhancing measurement accuracy. A binocular vision system was established, applying Zhang’s calibration method on the MATLAB (R2019a) platform to correct camera parameters, achieving a calibration error of 0.15 pixels. The study implemented block matching (BM) and semi-global block matching (SGBM) algorithms using the OpenCV (4.8.1) library on the PyCharm (2020.3.5) platform for stereo matching, generating disparity, and pseudo-color maps. Three-dimensional coordinates of key points on the piled material were calculated to measure distances from the vehicle container bottom and material surface to the binocular camera, allowing for the calculation of material pile height. Furthermore, a linear regression model was applied to correct the data, enhancing the accuracy of the measured pile height. The results indicate that by employing binocular stereo vision and stereo matching algorithms, followed by linear regression, this method can accurately calculate material pile height. The average relative error for the BM algorithm was 3.70%, and for the SGBM algorithm, it was 3.35%, both within the acceptable precision range. While the SGBM algorithm was, on average, 46 ms slower than the BM algorithm, both maintained errors under 7% and computation times under 100 ms, meeting the real-time measurement requirements for combine harvesting. In practical operations, this method can effectively measure material pile height in transport vehicles. The choice of matching algorithm should consider container size, material properties, and the balance between measurement time, accuracy, and disparity map completeness. This approach aids in manual adjustment of machinery posture and provides data support for future autonomous master-slave collaborative operations in combine harvesting.

Abstract Purpose To characterize the phenotype and genotype of a Chinese family with autosomal‐dominant retinitis pigmentosa (RP) accompanied by iris coloboma. Methods The proband, a 34‐year‐old male, was examined with his family by using fundus photography, optical coherence tomography (OCT), autofluorescence, and full‐field electroretinography (ffERG). Genetic analyses were conducted through whole‐exome sequencing (WES) to screen for variations. Results Three members of this Chinese family were shown to be bilateral iris coloboma. The male proband and his mother exhibited typical RP feature. The proband's late grandfather had been documented manifestation of iris coloboma. The mode of inheritance was confirmed to be autosomal dominance. Through linkage analysis and WES, a heterozygous variation in the miR‐204 gene (n.37C>T), a noncoding RNA gene, was identified in these three members. Conclusions In this third independent and the first Asian family, the existence of a miR‐204 variant associated with RP accompanied by iris coloboma was confirmed. Our findings reinforce the significance of miR‐204 as an important factor influencing visual function in the retina. When phenotypes like RP accompanied by iris coloboma in an autosomal‐dominant pattern, including in Chinese patients, miR‐204 aberrations should be considered.

C12H12N2O8Co, orthorhombic, Pbca (no. 61), a = 11.4542(10) Å, b = 9.2421(8) Å, c = 25.501(2) Å, V = 2699.6(4) Å3, Z = 2, Rgt (F) = 0.0342, wRref (F2) = 0.0888, T = 296 K.

Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by the accumulation of large amounts of phospholipid protein-like surfactant material in the alveolar spaces, leading to severe hypoxemia and respiratory failure. The disease has an insidious onset and is difficult to diagnose in the early stages. Its clinical manifestations primarily include progressive dyspnea and coughing. Currently, whole lung lavage (WLL) is the preferred and effective treatment for PAP, as it improves alveolar ventilation function. Granulocyte colony-stimulating factor is used clinically in the treatment of a variety of disease. Nebulized granulocyte–macrophage colony-stimulating factor (GM-CSF) has a certain therapeutic effect on PAP. Here, we report a case of PAP treated with WLL combined with nebulized GM-CSF, which achieved good therapeutic effects during a 4-year follow-up period, to enhance understanding of the disease.

Objective To quantify the setup errors for the different anatomical sites of patients who received intensity-modulated radiotherapy (IMRT) with linear accelerator on-board kilovolt fan beam CT(kV-FBCT) as non-isocenter IGRT and megavolt cone beam CT (MV-CBCT) as isocenter IGRT. Methods A retrospective analysis was performedon 70 patients who underwent radiotherapy, kV-FBCT, and/or MV-CBCT scans after each routine setup prior to IMRT. The average displacement (M), systematic error (Σ), and random error (б) at different treatment sites in the left-right, anterior-posterior, and cranial-caudal directions were calculated according to the individual displacements. The formula 2.5Σ+0.7б was used to estimate the PTV margin in respective direction. For each single patient, the root mean square in three directions was used as 3D displacement. Results A total of 1130 displacements were recorded in the 70 patients. The PTV margin was estimated to be 1.9-3.1 mm in head and neck cancer, 2.8-5.1 mm in thoracic cancer, 4.6-5.1 mm in breast cancer, 3.0-5.5 mm in upper abdominal cancer, and 3.5-6.8 mm in pelvic tumor. For the 3D mean displacements, the head and neck, thoracic, breast, upper abdominal, and pelvic cancer were 2.4±1.0, 4.0±1.6, 4.1±2.0, 4.6±2.1, and 4.6±2.1 mm, respectively. The average 3D displacement obtained by kV-FBCT and MV-CBCT were 4.1 and 3.4 mm, respectively (P=0.212). Conclusion The quantitative setup-error data can be obtained using linear accelerator on-board FBCT, and the non-isocenter IGRT induced set-up error cannot be negligible.

In the present work, we introduced a novel way to study the Tafel slope of titanium in passive state based on potentiodynamic test with a break by potentiostatic polarization. The power law model as well as surface analysis methods such as AES and XPS were also introduced to character the thickness and composition of the film. Results indicate that the Tafel slope of titanium electrode in the passive state increases with the applied overpotential. The anodizing constant is found to be equal to about 0.24–0.46 Å/s and 4–10 Å/V. The results showing highly consistent with AES and XPS results. The passive film are mainly composed of TiO2 predominantly outer layer, and titanium sub-oxide, Ti(OH)x predominantly inner layer.

The non-rotating trans-media vehicle can better adapt to the hypersonic flight conditions, but new problems in the hydrodynamic characteristics and motion stability arise during the water entry process. With the VOF multiphase model, Realizable k-ε turbulence model, and Schnerr-Sauer cavitation model, this paper establishes a simulation method of coupling the movement of non-roating body into water with multiphase flow fields based on overset grid technology, and the accuracy of the established model is verified. The simulation calculation of the oblique water entry process of the vehicle with different ratio of short axis to long axis in cross section is carried out. And the results show that although the ratio of short axis to long axis in cross section does not change the cavitation morphology, it affects the hydrodynamic and kinematic characteristics of the vehicle by influencing the relative position of the cavitation. As the ratio of short axis to long axis decreases, the motion stability of the vehicle increases gradually. However, if the ratio of short axis to long axis is too small, the drag reduction effect will be weakened, and the structure will suffer a bigger load.

Objective To analyze the clinical characteristics of thyroid LCH to enhance understanding of the disease. Methods We retrospectively studied the clinical data from six thyroid LCH patients who hospitalized in Huashan Hospital Affiliated to Fudan University from January 2015 to January 2022.We analyzed the ultrasound and 18F FDG-PET/CT imaging characteristics of thyroid LCH. Results The six patients diagnosed (2 males and 4 females) were between 18 and 58 years old.All patients had diabetes insipidus.MRI revealed thickened pituitary stalk.Two cases had central hypothyroidism, while four cases euthyroidism.Three cases tested positive for thyroid antibodies.Ultrasound showed thyroid nodules of TI-RADS 3 in three cases, TI-RADS 4 in two cases, and 1 with nodular goiter.Ultrasound showed that all sic cases indicated low echogenicity, 5 of which clear boundaries, 4 of which uneven echo distribution, 5 of which irregular shape, and noen has calcification.18F FDG-PET/CT indicated high uptake nodules with SUVmax values all above 10.4 cases were diagnosed by surgical excision and the other 2 by coarse-needle aspiration biopsy.When diagnosed, two cases had liver and thymus involvement respectively.One case had lung and bone involvement respectively.After treatment, 4 cases showed that nodular goiter shrank, while the other two with liver involvement progressed fast and no assessment made. Conclusions Thyroid LCH presented low echogenicity, clear boundaries, irregular shape, without calcification, and high uptake in 18F FDG-PET/CT.A definite diagnosis of pituitary stalk thicking accompanied by thyroid nodules, especially those with hypoechoic and irregular nodules, can be achieved by coarse-needle aspiration biopsy and langerin-specific pathological staining.

ObjectiveTo examine perfluorooctanoic acid （PFOA）-induced DNA damage using a combined in vivo and in vitro experiment.MethodsAcellular nuclear DNA damage was used as a model to test the damage induced by exposure to 0.00， 0.13， 0.25， and 0.50 mmol/L PFOA for 1 h. The YAC-1 cell was used as the research model. In the cytotoxicity study， the effects of different dosages on cell activity were determined via CCK-8 assay. The final PFOA concentrations were 0， 1.0×10-8， 1.0×10-7， and 1.0×10-6 mol/L. DNA damage was detected after 3 d of exposure. Rats were gavage with 0， 10， 20， 40 mg/kg·BW PFOA twice. The liver， bone marrow， and peripheral blood of rats were removed 6 h after the last administration. Alkaline and neutral comet assay were performed to measure DNA damage. The micronucleus test was performed to measure bone marrow chromosome breakage.ResultsCompared with the control group， acellular and cell alkaline DNA comet assay result showed that the tail DNA% of acellular nuclear DNA increased significantly in each dose group （P0.05）. The tail DNA% of each dose group in the alkaline comet assay was significantly higher than that of the control group （P0.05）. Compared with the control group， the alkaline and neutral comet assay results showed that the tail DNA% of bone marrow， liver， and peripheral blood cells group showed no DNA breakage in each dose group （P>0.05）. Compared with the control group， the test of bone marrow micronucleus was negative （P>0.05）.ConclusionPFOA can cause DNA single-strand breakage at the subcellular level in vitro， and exposure does not induce DNA and chromosome breakage in rats after oral exposure.

The nickel content of nickel-based high-temperature alloy is between 50% and 70%, and the alloy contents of chromium, iron, cobalt, molybdenum, aluminum, titanium and tungsten are within 20%. A method of high resolution plasma mass spectrometry was established to determine the trace elements in nickel-based high-temperature alloy. According to the principle of large isotope abundance, small interference and high sensitivity, the isotopes and resolution of the elements to be measured were optimized, the interferences of most of the multi-atom and double-charged ions were effectively eliminated. The mass spectral interferences of matrix, compositions of alloy and dissolving acid on the trace elements were investigated. The appropriate internal standard of caesium was selected to overcome the matrix effect and reduce the signal drift. Chromium was extracted by methylisobutylone, the extraction efficiency reached up to 99.7%, which eliminated the mass spectral interference of principal component molybdenum in the nickel-based high-temperature alloy. The linear correlation coefficient of the calibration curve was greater than 0.999, and the method detection limit was between 0.002 1 and 0.074 μg/g. The trace elements in the reference material was analyzed, the relative standard deviation (RSD, n=6) was between 2.9% and 7.8%, and the measured value was very consistent with the standard value. This method is simple, fast, accurate and reliable, which can meet the requirement of trace elements determination in nickel-based high-temperature alloy.

To study the characteristics of the present crustal movement in the Tibetan Plateau and explore its relationship between strong earthquakes with magnitudes of 8 and above, the velocity field size was analyzed based on the global position system (GPS) campaign observations and the time series of site north-ward displacement and long baseline were discussed using the GPS continuous observations. The results show that the velocity field size in the Tibetan Plateau decreases from southwest to north, northeast, and southeast, and the value of the velocity in the west is significantly greater than that in the east in the same dimension. The maximum value is located in the southwest and the minimum value is located in the east. The Wenchuan earthquake is located in the mutation region, where the rate and the direction of the crustal movement are quite different. The crustal deformation extent is large in the region close to the seismic source before the earthquake, reflecting that the regional stress accumulation is fast and its required time is relatively short. However, the crustal deformation extent is relatively small in the region away from the seismic source before the earthquake, reflecting that the regional stress accumulation is slow and its required time is relatively long. The N-ward movement became significantly strong after Nepal M S 8.1 earthquake; the occurrence of this earthquake may have caused the unlocking of large-scale faults near the seismic source, which further intensified the NE-ward subduction and collision of the Indian Plate. The compression of the Indian Plate to the Tibetan Plateau slowed down after the 2008 Wenchuan M S 8.0 earthquake, and increased significantly after 2015, which boosted strain accumulation in the Tibetan Plateau, and attention needs to be paid continuously to strong earthquake risk in this region.

New social, economic, cultural, and technological trends bring new challenges to designers, and the use of data intelligence analytics is a very promising way to improve the efficiency and quality of their results. In this paper, we use convolutional neural networks to improve and optimize the GAN model, resulting in a more stable DCGAN network model. Visual innovation-related features are inputted into the discriminator in the DCGAN model, and creative visual images are automatically generated in the generator under the constraint label restriction. The network parameters of the DCGAN model are optimized through the training process to construct the brand image design process of automated visual creativity. The performance test analysis of the DCGAN model reveals that the analysis results of its IS index and FID index values are much higher than those of the WGAN and CGAN models, indicating that the generated visual creative images have high quality. The analysis of the visual creativity of the designed brand image found that the subjects’ favorability of the brand image intended by the DCGAN model reached 3.57 points on average and brought a visual feast to the subjects. This paper provides support for the application of Generative Adversarial Networks in the field of brand image design and achieves automated brand creative image design.

The environment of open-pit mines is distinctive, and the conditions of the roads in them are complex and constantly changing. Insufficient lighting in the area being mined can make it challenging to identify and position multiple targets on the roads. This, in turn, affects the results of detection and poses serious risks to the safe operation of uncrewed mining trucks.Currently available models to identify obstacles on roads cannot accommodate the impact of poor lighting, and thus, yield inaccurate results. They also have significant shortcomings in identifying small obstacles in the mining area. In this study, we develop a multi-target model of detection for the dark/light environment of an open-pit mine using hyperbolic embedding to address the above-mentioned issues. We introduce the Retinex-Net convolutional neural network to the image preprocessing stage of the detection model to enhance dark images and improve their clarity. To address the issue of an excessively large number of features in the dataset without a clear preference for focus, we incorporate the global attention mechanism into the improved process of feature extraction. This enabled the collection of critical feature-related information in three dimensions. Finally, we incorporate a fully connected hyperbolic layer into the prediction stage of the model to minimize feature loss and prevent overfitting. The results of experiments to verify the proposed model showed that ① it could reliably classify and accurately identify large-scale targets in the low-light environment of the open-pit mining area, and was able to highly accurately identify mining trucks and small vehicles over long distances. It could also accurately identify and locate scaled targets, including pedestrians, such that this satisfies meeting the safety-related requirements of uncrewed mining trucks operating in diverse environments.② The model achieved an accuracy of detection of 98.6% while maintaining a speed of 51.52 frames/s, where this was 20.31%, 18.51%, 10.53%, 8.39%, and 13.24% higher than the accuracies of the SSD, YOLOv4, YOLOv5, YOLOx, and YOLOv7, respectively. Its accuracy of detection of pedestrians, mining trucks, and excavators on mining roads exceeded 97%.

With the construction of China’s socialist modernization, the social demand for practical talents is increasing. In this paper, in the multi-objective optimization problem of social practice parenting in colleges and universities, each planning objective is assigned to select an adaptability function. And the individuals are sorted and stratified according to the calculated fitness values to generate sub-fitness tasks that are more suitable for promoting individuals in each layer. Finally, using college students and faculty members from five universities in province G as a research case, the entropy weight method is used to calculate the weights of secondary indicators in the multi-objective optimization model, which together form a set of particle vectors and search for the optimal solution within a limited range. The results show that the final calculation of the indicators affecting social practice in colleges and universities yields a mean value of 4.27, close to the set value of 5. It shows that the multi-objective optimization has good adaptability and the solution results are more accurate. At the same time, it is found that the empirical measurements are all in line with the actual situation of the universities, which once again shows that the model’s design is reasonable and practical.

Chinese national community consciousness is the ideological foundation for realizing the Chinese dream. The influence of ethnic literature promotion on national community consciousness is examined through a multiple linear regression model in this paper. Using the empirical analysis method and the data from the Questionnaire for Predicting the Main Factors Affecting the Chinese National Community Consciousness, the paper conducts correlation and regression analyses on the overall level, group differences, and influencing factors of the Chinese national community consciousness at different stages, and draws out the overall characteristics of the Chinese national community consciousness and the reasons for the differences in the promotion of ethnic literature. As shown by the results, there is a strong correlation between the promotion behavior of ethnic literature and Chinese national community consciousness, with a correlation coefficient of 0.584. The mediating variable’s perceived confirmation of community consciousness has a significant regression coefficient of 0.372. The research in this paper provides the most direct empirical evidence for the behavioral tendency to build a strong sense of the Chinese national community and maintain the unity of the national community.

This paper uses affective computing and mood measures to calculate the negative emotional status of college students during school closures. The psychological data of university students at the University of H were counted using the affective computing model and psychometric methods, the frequency of their negative emotion words was mined, and the changes of each psychometric index were analyzed in terms of the time dimension, stressor, anxiety status, and emotional state, respectively. The epidemic closure period had a great negative impact on students. From January 20 to December 20, 2021, college students’ positive mood characteristic value declined. The negative mood characteristic value increased, and the negative mood characteristic value was always higher than the positive mood characteristic value. Finally, the negative mood characteristic value of 0.27 was much higher than the positive mood characteristic value of 0.07, and there were various discomforts such as about 40% of people were nervous, depressed, lacked motivation, and had diminished interest; at the same time, feelings of difficulty in accomplishing goals, failure, fear, anxiety, and frustration emerged. The epidemic closure greatly impacted students’ psychology, and students’ psychological problems need to be taken seriously and receive timely guidance.

Hand hygiene is one of the most important measures to prevent nosocomial infections. This paper introduced the design and application of a hand sanitiser bottle with timer. This hand sanitiser bottle has been designed to improve the cleaning and disinfection efficiency, and provided a more precise timing of fertilizer application. (手卫生是预防院内感染的重要措施之一。本研究设计一种带有计时器的消手液瓶, 简化计时操作, 有助于医务人员更精准地掌握消毒时间, 有效提高清洗消毒效率。)

C24H15NO2S2, monoclinic, P21/c (no. 14), a = 20.8250(11) Å, b = 5.3649(3) Å, c = 18.8787(11) Å, β = 106.278(2)°, V = 2024.7(2) Å3, Z = 4, Rgt(F) = 0.0439, wRref(F2) = 0.1015, T = 273 K.

【Objective】 Low water and fertilizer use efficiency and environmental pollution caused by excessive water and fertilizer supply are common in vegetable production. Taking spinach as an example, this paper studies the effect of irrigation and fertilization amount and method on its yield and quality. 【Method】 The experiment was conducted using a solar radiation irrigation controller to manage the irrigation and fertilization in that it started irrigation and fertigation when the accumulated solar radiation reached a pre-set threshold. We compared four treatments: low irrigation and fertilization (W1), moderate irrigation and fertilization (W2), sufficient irrigation and fertilization (W3), moderate irrigation without fertilization (W4). The control was conventional irrigation and fertilization used by local farmers (CK). 【Result】 The height and yield of the spinach in W5 were lower than that in W2 and W3. W5 led to the highest nitrate content in spinach and highest EC in soil after harvest. The height and yield of the spinach in W1 and W4 were the lowest. Nitrate content in the spinach, nitrate content and EC in the soil were the lowest in W4. W2 and W3 gave the highest plant height and yield. There was no significant difference in plant height and yield between W2 and W3, even though W3 used 1.4 times more water and fertilizer than W2. Nitrate content in spinach leaves in W3 was 1.4 times higher than that in W2. 【Conclusion】 For all treatments we compared, W2 was optimal for reducing water and nitrogen application without compromising spinach yield and quality.

In order to study the effects of microstructure and mechanical properties of 20Cr carburized steel high-speed linear guide under different aging treatment conditions, the microstructure, phase composition and residual stress of linear guide before and after aging treatment were analyzed by scanning electron microscopy (SEM), Х-ray diffractometer (XRD) and X-ray stress tester. The results show that after aging treatment, the martensite structure in the surface layer of 20Cr carburized steel is gradually refined, the fine carbides is precipitated and some residual austenite decompose, the surface hardness of the guide rail increases and the maximum hardness is 729.3HV1/5. Affected by the transformation of residual austenite structure and the change of ferrite content, the residual stress of the carburized layer of the guide rail is eliminated to varying degrees. After heated to 200 °C for 13 h, the residual stress relief effect on the surface of the guide rail is the most obvious, the residual stress value is reduced to -127.17 MPa and the elimination rate is as high as about 54.05%, and there is a polynomial function relationship between the residual stress and the depth of the carburized layer.

Water ramjet is the most ideal power propulsion device for high-speed underwater weapons. However, failure to start it at low-speed makes it hard for the engine to be widely used. In order to solve the problem of starting water ramjet at low-speed, a configuration scheme of water ramjet pressurized water intake system of the micro-turbine driving micro-mixed-flow pump is proposed. The design method of micro-turbine and micro-mixed-flow pump is perfected. And the simulation model of turbine and mixed-flow pump is established. The rationality of the design results was verified by numerical simulation. The matching design of the turbine and the mixed-flow pump is completed. And the working performance of the pressurized water inlet system is analyzed. The results show that the maximum relative deviation between the design results of the turbine and the pump and the target value is less than 3.2%, and the booster system can increase the fluid pressure by 2.0 MPa, reducing the starting speed of the ramjet from 90 to 63 m/s. The research results of this paper have reference value for the engineering application of water ramjet technology.

Aimed at the phenomenon of variable overburden spatial structures and complex disaster factors in multi-face mining in a geological anomaly area of a mine, taking the actual geological occurrence conditions and mining technology conditions as the engineering background, this paper studied the changes rule of overburden spatial migration structures and the distribution characteristics of abutment pressure in the geological anomaly area by theoretical analysis and numerical simulation. Taking single-layer bending thin plate as an example, mechanical models of plates at different mining stages were established, and the characteristics of bending energy release of plates at different mining stages were revealed. Based on the structural regulation theory, the prevention measures of rock burst at the beginning and end of mining were proposed to reduce the collapse span of thick and hard rock strata. The main conclusions were as follows: ①With the successive mining of multiple faces working, the overburden spatial structure evolution of “一” → “S”→ short “Ω”→ irregular “Ω”→ long “Ω” →“O”→shaped overburden spatial structures has been experienced in the area of geological anomalies successively, enriching the types of overburden spatial structure; ②Due to the influence of geological anomalies, more initial pressure and “square” pressure are borne in the mining process of multiple faces working. The dynamic load disturbance and abutment pressure distribution of roof collapse in this area were more complex and changeable, which were easy to cause the risk of overall instability rock bursts of wide coal pillar; ③Based on the mechanical model of single-layer bending thin plate, it was concluded that the bending energy of different plate structures increased exponentially or linearly with the length of the side, and the free edge had a greater influence on the bending energy than the fixed edge; ④The effect test of the pre-pressure relief and danger relief measures showed that there were no big micro-seismic energy events in the working face mining process and the coal body stress remained stable. The structural control measures basically guaranteed the prevention effect of rock burst at the beginning and end of the multi-working face mining in the geological abnormal area.

Abstract Endometrial cancer (EC) is one of the most common gynecologic malignancies. Identification of potential EC biomarkers is essential to improve the prognosis and development of therapies against EC. Synaptotagmin-like protein 1 (SYTL1), as a small GTPase Rab27 effector, mainly plays a role in vesicle trafficking and cytotoxic granule exocytosis in lymphocytes. However the role of SYTL1 in EC remains uncertain. We performed a comprehensive assessment of the relationship between SYTL1 and patient diagnosis and prognosis by analysis of EC patients’ data from TCGA. We employed the LinkedOmics and Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database to analyze the biological function of SYTL1 in EC. In addition, the correlation between SYTL1 expression and its DNA methylation was performed by using cBioportal, UALCAN, TCGA Wanderer and MethSurv databases. We further assessed the link between SYTL1 and tumor-infiltrating immune cells by using gene set variation analysis (GSVA). Results We found that SYTL1 was highly expressed in EC patients and cell lines. And increased expression of SYTL1 was associated with age, clinical stage, histological type, histological grade and good overall survival (OS).SYTL1 DNA methylation is negatively associated with SYTL1 expression and UCEC patients’ OS. SYTL1 expression is closely correlated with immune infiltration. Furthermore, we carried out in vitro experiments to verify the results of bioinformatic analysis. Conclusion Our results demonstrated that the elevation of SYTL1 expression is associated with good OS and SYTL1 might be a potential diagnostic and prognostic marker in EC.

Abstract Pregnant women infected with HCV should be given attention due to their special physiological stage and the effect on offspring health. To examine the prevalence of HCV infection among pregnant women in part of China and explore relevant factors during pregnancy, a cross-sectional study was conducted in four maternal and children health care institutions (MCHC) in Guangdong, Hunan and Chongqing. Pregnant women who were delivered, induced or spontaneous abortion were included and relevant information was collected through the Hospital Information System. Results showed that the prevalence of HCV among pregnant women in four MCHCs was 0.11% (95% CI 0.09–0.13%). Age, occupations, regions, syphilis-infection, intrahepatic cholestasis of pregnancy (ICP), and placenta previa were significant factors (all P

Improving cost efficiency is one of the main ways to reduce the production cost of agricultural products and increase farmers' income. Human capital is an important way to improve cost efficiency. This article takes five major corn production areas as an example, uses data envelopment analysis to measure the cost efficiency and makes an empirical analysis of the impact of human capital on cost efficiency and its action path by using bidirectional fixed-effect model. It is found that the impact of educational human capital on cost efficiency presents a positive ‘U' shape, and there are differences among different regions through technical efficiency and allocation efficiency paths. Healthy human capital has a significant positive impact on cost efficiency, but with the increase of the number, its role will gradually weaken, except for the southwest region, and its impact path is allocation efficiency. The impact of technical human capital on cost efficiency shows a positive ‘U’ type change, and the change of each production area is roughly the same as the whole. Its impact on cost efficiency is mainly realised through allocation efficiency. This article provides a theoretical basis for different policy measures to better play the role of human capital in improving cost efficiency in China.

In this study, copper nanoparticles were synthesised according to green chemistry rules using the aqueous extract of Alhagi maurorum. The green-synthesised CuNPs were characterised using different techniques such as EDX, FE-SEM, XRD and FT-IR. The FE-SEM results confirm spherical morphology for the nanoparticles with a size of 42.68–68.87 nm. In vivo, the Mycoplasma pneumonia injection was applied for inducing pneumonia in the BALB/c mice, also the treatment was with CuNPs. The serum parameters such as inflammatory mediators (IL-6, TNF-α, IL-8, TGF and IL-1), total cell counts, and total protein content levels were evaluated. CuNPs regulated the levels of the inflammatory mediators in the infected mice. The cellular arrangements at the histopathological images were ameliorated with the administration of CuNPs. At the antioxidant test, the CuNPs and BHT removed 50% of free radicals at the concentrations of 181 and 110 µg/ml. In conclusion, the results revealed the ameliorative property of CuNPs green-formulated by A. maurorum aqueous extract on M. pneumoniae infected pneumonia mice model.

Background and purpose: Microsatellite instability (MSI) and mismatch repair (MMR) defects have attracted much attention recently as one of the important biomarkers for pan-tumor immunotherapy such as colorectal cancer (CRC). Conventional methods for MSI detection with polymerase chain reaction (PCR) often require non-tumor controls as well as a long turnaround time. The IdyllaTM system as a fully automated quantitative PCR unit with a turnaround time of only 2.5 h should be proved for its reliability among Chinese CRC patients before application. Methods: Formalin-fixed paraffin-embedded (FFPE) tissue samples were collected from 87 CRC patients in Fudan University Shanghai Cancer Center from March 2017 to March 2019 and were subjected to detect MMR protein expression and MSI using immunochemistry (IHC), conventional PCR (Promega MSI analysis) and the IdyllaTM MSI system, respectively. Results: Of the 87 CRC patients enrolled, 56 cases were identified to be deficient MMR (dMMR)/MSI-high (MSI-H) and 31 to be proficient MMR (pMMR)/microsatellite stable (MSS) by both IHC and Promega MSI analysis. However, 4 cases with dMMR/MSI-H were determined to be MSS and one case with pMMR/MSS to be MSI-H using IdyllaTM MSI system, yielding a sensitivity of 92.9% (52/56), specificity of 96.8% (30/31) and an overall concordance of 94.3% (82/87). Then, the above five discordant cases were re-examined using IdyllaTM with resection tissues, as a result, four cases with ≥20% tumor contents changed to be consistent with IHC/Promega MSI assay, however, there was still one inconsistent case with only 5% tumor content. Subsequently, the case was reconfirmed using IdyllaTM with enriched tumor tissue by macrodissection, as expected, the result was demonstrated to be MSI-H, consistent with Promega MSI analysis and IHC. Furthermore, repeatability of the IdyllaTM MSI assay was proved to be reliable in 5 cases with various tumor contents (20%-60%). Conclusion: The IdyllaTM MSI system provides a fast, reliable and fully automated solution to MSI detection in Chinese CRC patients with high sensitivity, specificity and reproducibility, especially for CRC with more than 20% tumor contents.

Objective To evaluate the application and nursing effects of M3 machine nickel-titanium file in one-time root canal therapy for the elderly patients. Methods Totally 160 elderly patients with chronic pulpitis who needed root canal therapy were treated with one-time root canal therapy. They were randomly divided into two groups with 80 cases in each group, including premolars and molars. In the experimental group, the root canals were prepared with M3 nickel-titanium rotary instruments (M3-Path file and M3 Pro file). In the control group, the root canals were dredged and prepared with traditional hand root canal instruments (C-file and K-file). The treatment time and postoperative pain between the two groups were compared. This paper also expounded the factors concerned by nurses about nursing before, during and after treatment. Results A shorter time of premolar and molar root canal preparation was observed in the experimental group than that in the control group (P＜0. 05). The outcome of postoperative pain assessment of the experimental group was significantly lower than that of the control group (P＜0. 05). Conclusion The use of nickel titanium file for M3 machine combined with high-quality nursing can significantly shorten the root canal preparation time and reduce postoperative pain response, showing a positive value of shortening the time required for nurses' chair cooperation, improving clinical work efficiency and making patients get more satisfactory medical services. (目的 评价M3机用镍钛锉在老年患者一次性根管治疗应用中的优势及护理效果。方法 选取临床诊断为慢性牙髓炎且需要进行一次性根管治疗的老年患者160例(患牙包括前磨牙及磨牙), 随机分为两组, 各80例。研究组使用M3机用镍钛锉(M3-Path通道锉、M3 PRO镍钛锉)疏通、预备根管, 对照组采用传统手用根管器械 (C型锉、K型锉)。对比两组的治疗时间和术后疼痛评分, 评价护理效果。结果 研究组患牙根管预备时间短于对照组, 差异有统计学意义(P＜0. 05); 研究组患者术后平均疼痛分值低于对照组, 差异有统计学意义(P＜0. 05)。结论 M3机用镍钛锉的使用与高质量的护理配合可缩短根管预备时间, 降低术后疼痛反应, 对缩短护理人员椅旁配合时间、提高临床工作效率和患者满意度具有积极意义。)

Objective To investigate the expression and its significance of H3K27me3 in Tibetan patients with gastric cancer. Methods Clinical and pathological data were retrospectively collected from Tibetan patients with gastric cancer in the Tibet Autonomous Region People's Hospital from August 2019 to August 2021 and Tibetan non-gastric cancer patients during the same period. The expression of H3K27me3 in gastric cancer tissues, corresponding adjacent normal gastric mucosa and normal gastric mucosa of Tibetan patients with non-gastric cancer tissues was detected by immunohistochemical method, and the differences of H3K27me3 expression between gastric cancer patients with different clinical and pathological characteristics was compared. Results A total of 54 Tibetan gastric cancer patients and 55 Tibetan non-gastric cancer patients who met the inclusion and exclusion criteria were enrolled. H3K27me3 was localized in the nucleus, and the nucleus showed brownish-yellow granular staining when positively expressed. The high expression rate of H3K27me3 in gastric cancer tissues was significantly higher than that in adjacent normal gastric mucosa tissue[64.8%(35/54) vs. 29.6%(16/54), P < 0.001]and normal gastric mucosal tissue of Tibetan patients with non-gastric cancer[64.8%(35/54) vs. 34.5%(19/55), P=0.002], and the high expression rate of H3K27me3 in the adjacent normal gastric mucosa tissue was not significantly different from that in normal gastric mucosal tissue of Tibetan patients with non-gastric cancer(P=0.683). H3K27me3 expression in gastric cancer tissues was not related to gender, age, degree of differentiation, depth of invasion, maximum tumor size, Lauren's classification, lymph node metastasis, vascular and nerve invasion and TNM stage. Conclusions H3K27me3 is highly expressed in gastric cancer tissues of Tibetan people in Tibet. There is no significant difference in H3K27me3 positive expression cells in adjacent tissues and normal gastric mucosa. The significance of H3K27me3 in Tibetan patients with gastric cancer is uncertain and requires further investigations.

Aiming at the reservoir damage of low-yield coalbed methane wells in Junggar Basin block during the drainage stage, in this paper, the drainage situation of typical coalbed methane wells in the block is systematically analyzed and reservoir damage types and prevention and control methods of coalbed methane wells in the drainage stage are discussed. The results show that the main types of reservoir damage at the drainage stage in the study area include stress sensitivity, velocity sensitivity and water lock damage. The low mechanical strength of coal reservoirs, improper fracturing fluid, and high drainage intensity are the important reasons for these damages. During the drainage stage of CBM wells, drainage is carried out according to the “continuous, slow and stable” guidelines, increasing the expansion range of the pressure drop funnel and keeping the fluid flow rate below the particle start flow rate will help prevent the three types of reservoir damage. In addition, the use of low-damage fracturing fluid with low surface tension and strong wettability can promote the rapid sedimentation and aggregation of particles. The pore capillary pressure is significantly reduced in the reservoir in the reconstruction stage, thereby inhibiting reservoir velocity sensitivity and water blocking damage. Meanwhile, the coal reservoir is retrofitted by surrounding rock, which helps to reduce the impact of stress-sensitive damage on the production of coalbed methane.

In the context of the operation of China’s carbon emissions trading market, carbon cost pass-through will profoundly impact the country’s power generation industry. However, the core of studying carbon cost pass-through in the power generation industry is determining the carbon cost pass-through rate (CCPTR). Based on this, this paper first takes the Cournot model as the basic principle, which analyzes the impact of different power generation enterprises’ numbers and the characteristics of electricity market demand on the carbon pass-through results. Secondly, based on the Cournot model, this paper further CCPTR under marginal cost variability. The research results show that when the demand function is linear, the larger the CCPTR, the larger the proportion of carbon cost pass-through. When the demand function is isoelastic, the smaller the CCPTR, the smaller the proportion of carbon cost pass-through.

Biogranules are recently regarded as promising methods with intensive density and satisfying settleability for waste treatment and resource recovery. Wastewater treatment plants (WWTP) were regarded as “sinks” for Microplastics (MPs) and amount of MPs entrapped in the sludge. MPs have been reported to harm the granular characteristics and wastewater treatment efficiency. Previous research stated that the harmful effect on granular sludge is closely associated with the sizes and concentrations of MPs. However, there is still a lack of a comprehensive summary of granular characteristics variation and further investigation of its influential mechanisms for treatment capability. This work gives informative clues for the regulation mechanisms, especially the microorganisms’ response after the exposure of MPs, and provides fundamentals for stable operation and risk control strategies using granular sludge in treating microplastics containing wastewater.

Museum digitization, the process of utilizing digital technology to record, manage, and showcase museum collections, represents a significant transformation in the modes of cultural and historical heritage preservation. As pivotal institutions tasked with the preservation, protection, and exhibition of human civilization achievements, museums have traditionally fulfilled these roles. The rapid advancement of information technology has made museum digitization a global, irreversible trend. This process involves the conversion of tangible collections into digital formats, breaking through the physical constraints of time and space, thereby providing the public with a more convenient and enriched cultural experience.

Atmospheric corrosion monitoring and evaluation are important means for studying the mechanism and behavior of atmospheric corrosion of metals. In view of the long cycle, cumbersome process, and poor data quality of the traditional outdoor hanging method, an innovative atmospheric corrosion data monitoring system has been designed to detect atmospheric environment data and metal corrosion data on site, and display the detection data of the equipment’s service location to users in real-time in the form of a “dynamic corrosion map”. This can provide a differentiated design for the anti-corrosion of important equipment such as power grid transmission and transformation engineering components Provide effective data support for engineering life prediction and operation and maintenance. At present, the system has been piloted and promoted in some network provinces, achieving good social and economic benefits.