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Aim The aim of this study was to evaluate the efficacy of ridge preservation involving novel devices used for obturation of socket orifice (Socket cap; SocketKAP™) and resorbable cage used for space maintenance in sites with facial wall dehiscence (Socket cage; SocketKAGE™). Material and Methods Eight teeth were extracted in each of six Macaca fascicularis non-human primates. Six intervention groups consisted of the following: Group A: intact socket negative control. Group B: intact socket: socket cap. Group C: intact socket filled with anorganic bovine bone mineral ( ABBM) + socket cap. Group D: dehiscence: negative control. Group E: dehiscence: socket cap + socket cage. Group F: dehiscence: filled with ABBM + socket cap + socket cage. CBCT scans were obtained preoperatively and at 6 and 12 weeks following intervention. The pre- and postoperative scans were superimposed, to quantify 3D volumetric alveolar bone changes. Results Volumetric bone loss occurred in all sockets, not only within the cretal zone (0-3 mm) to the ridge crest, as has been commonly reported by other investigators, but significant bone loss was also detected in the zone which was 3-6 mm apical to the alveolar crest. For intact sockets, socket cap + ABBM led to significantly greater percentages of remaining bone volume when compared to groups A and B. A significant difference favoring socket cap + socket cage + ABBM treatment was observed for sockets with facial dehiscence defects compared to groups D and E. Conclusions Socket cap in conjunction with ABBM appears effective in limiting post-extraction volumetric bone loss in intact sockets, while socket cap + socket cage + ABBM appears effective in limiting post-extraction bone loss in sockets with dehiscence defects. [ABSTRACT FROM AUTHOR]

Objectives The aims of this study were (i) to evaluate the efficacy of ridge preservation and repair procedures involving the application of Socket KAP™ and Socket KAGE™ devices following tooth removal and (ii) to evaluate alveolar bone volumetric changes at 6 months post-extraction in intact sockets or those with facial wall dehiscence defects using 3-dimensional pre- and postoperative CBCT data. Materials and Methods Thirty-six patients required 61 teeth extracted. Five cohorts were established: Group A: Intact Socket Negative Control Group B: Intact Socket + Socket KAP™ Group C: Intact Socket Filled with Anorganic Bovine Bone Mineral ( ABBM) + Socket KAP™ Group D: Facial Dehiscence Socket Negative Control Group E: Facial Dehiscence Socket Filled with ABBM + Socket KAP™ + Socket KAGE™. Preoperative CBCT scans were obtained followed by digital subtraction of the test teeth. At 6 months post-extraction, another CBCT scan was obtained. The pre- and postoperative scans were then superimposed, allowing highly accurate quantitative determination of the 3D volumetric alveolar bone volume changes from baseline through 6 months. Results Significant volumetric bone loss occurred in all sockets, localized mainly in the 0-3 mm zone apical to the ridge crest. For intact sockets, Socket KAP™ + ABBM treatment led to a statistically significant greater percentage of remaining mineralized tissue volume when compared to negative control group. A significant difference favoring Socket KAP™ + Socket KAGE™ + ABBM treatment was observed for sockets with facial dehiscence defects compared to the negative control group. Conclusions Socket KAP™, with ABBM, appears effective in limiting post-extraction volumetric bone loss in intact sockets, while Socket KAP™ + Socket KAGE + ABBM appears effective in limiting post-extraction bone loss in sockets with dehiscence defects. [ABSTRACT FROM AUTHOR]

Objectives The aims of this study were to evaluate (i) the efficacy of ridge preservation and repair involving Socket KAP™ and Socket KAGE™ devices following tooth removal; and (ii) ridge contour changes at 6 months post-extraction in intact sockets and sockets with dehiscence defects. Material and methods Thirty-six patients required a total of 61 teeth to be extracted. Five cohorts were established with groups A-C involving intact sockets and groups D and E involving facial dehiscence: (A) Negative Control; (B) Socket KAP™ alone; (C) Anorganic Bovine Bone Mineral ( ABBM) + Socket KAP™; (D) Negative Control; and (E) ABBM + Socket KAP™ + Socket KAGE™. Preoperative CBCT and laser-scanned casts were obtained. Teeth segmented from preoperative CBCT were merged with study cast images to allow for digital removal of teeth from the casts. Volumetric measurements of ridge contour were performed. Images of preoperative and 6 months post-operative casts were superimposed to measure ridge contour changes. Results Post-extraction contour loss occurred in all sockets primarily in the crestal 3 mm but was also detected up to 6 mm from alveolar crest. For intact sockets, Socket KAP™ or Socket KAP™ + ABBM interventions led to greater percentages of remaining ridge contour when compared to controls. A significant difference favoring Socket KAP™ + Socket KAGE™ + ABBM treatment was observed for sockets with facial dehiscence when compared to controls. Conclusion Socket KAP™, with or without ABBM, significantly limited post-extraction ridge contour loss in intact sockets. In the absence of a group treated with only the Socket KAGE™, it is not possible to determine its efficacy, although the combination of Socket KAGE™ + Socket KAP™ + ABBM was effective in limiting post-extraction ridge contour loss in sockets with dehiscence defects. [ABSTRACT FROM AUTHOR]