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Two binuclear Gadolinium(III) (Gd) complex [Gd2(L1)2(H2L3)2(NO3)2] (1) and [Gd2(L2)2(H2L3)2(NO3)2] (2) were obtained by using 2‐hydroxybenzaldehyde or 2‐hydroxy‐1‐naphthaldehyde, 2‐aminophenol, pyridin‐2‐ylmethanamine and Gd(NO3)3 ⋅ 6H2O in CH3CN (H2L1=(E)‐2‐((2‐hydroxybenzylidene)amino)phenol, H2L2=(E)‐1‐(((2‐hydroxyphenyl)imino)methyl)naphthalen‐2‐ol, H2L3=pyridin‐2‐ylmethanamine). Structural analysis suggests that all the ligands as protective units protect the central Gd(III) ions at the periphery. Magnetization studies exhibited magnetocaloric effect of 14.45 J ⋅ kg−1 ⋅ K−1 at 4 K under ΔH=7 T for complex 1 and 12.69 J ⋅ kg−1 ⋅ K−1 at 2 K under ΔH=7 T for complex 2. In complexes 1 and 2, although the coordination configurations are the same, the significant difference in MCE may be due to the adjustments of the peripheral ligands leading to changes in the coordination field strength. The electron affinity of the ligands can impact the interaction between the ligands and Gd(III) ions. [ABSTRACT FROM AUTHOR]

Two copper (II) complexes based on the mixed ligand system were synthesized and structurally characterized. The molecular formulae for complex (1), [Cu2L1L′] and complex (2), [CuL2L′] were determined based on analytical data, molar conductance, and thermal analysis results. The optimized structures of complexes (1) and (2) were determined by magnetic and spectroscopic measurements (FTIR, UV–Vis, and ESR) and confirmed by processing powder X‐ray diffraction data by Expo 2014 software. The geometry index (τ5), determined by ESR spectra and structural analysis based on powder X‐ray, demonstrates the square pyramidal geometry of the Cu (II) center of [Cu2L1L′] and [CuL2L′]. Cyclic voltammetry measurements were performed to elucidate the relationship between the redox properties of (1) and (2) and their oxidase‐mimicking catalytic activity. Catalytic aerobic oxidation of the polyphenols 3,5‐di‐tert‐butylcatechol (3,5‐DTBCH2), 4‐nitrocatechol, and 2‐aminophenol (2‐APH3) was studied by stopped‐flow technique. Promising catechol oxidase (COX) and phenoxazinone synthase (PHS) mimetic activity have been demonstrated for (1) and (2). Electrochemical data were used to determine the free energy (ΔG°) or driving force (−λ), and their correlation with the oxidase mimetic activity of(1) and (2) was examined. Several experimental procedures have been performed that have helped describe the catalytic mechanisms of the catalytic reactions taking place. [ABSTRACT FROM AUTHOR]

Metal–organic framework (MOF) membranes with apparent molecular sieving effects have great potential for gas separation. However, their application in light‐gas separation (e.g., CO2/CH4 and H2/CH4) remains challenging due to their enlarged pore structures under transmembrane pressure. In this work, a series of MOF membranes constructed from dual‐wing (DW) ligands including 2‐chloromethylbenzimidazole, 2‐methylbenzimidazole, 2‐ethylbenzimidazole, and 2‐phenylbenzimidazole are reported, to finely tune apertures and enhance molecule sieving property for small‐size gases. These DW‐ligands provide steric resistance in two directions perpendicular to the coordination bond, leading to a much finer pore structure. The introduction of the DW‐ligands endows the DW/ZIF‐8 membranes with an adjustable bottleneck door for regulating gas diffusion, blocking the transport of large‐sized CH4 while allowing small‐sized H2 and CO2 to permeate. The membranes show significantly improved molecular sieving property with a CO2/CH4 mixed‐gas selectivity of 58.6 in the case of 2‐chloromethylbenzimidazole23/ZIF‐8, which represents the highest value among the reported ZIF membranes. This membrane also exhibits exceptional separation performance for H2/CH4 and H2/C3H8 with separation factors of 430 and 34341, which are the highest values among the reported MOF membranes. This study presents a facile and efficient strategy for regulating MOF aperture and constructing high‐performance membranes for natural gas separation. [ABSTRACT FROM AUTHOR]

The current work reports the synthesis of mixed ligand‐metal complexes of (2‐(2‐oxoacenaphthylen‐1 ylidene)hydrazinecarbothioamide) (L1) and carbamothioyl‐2‐chloronicotinohydrazonic acid (L2) and imidazole (im), triphenylphosphine (PPh3) and pyridine (py) ligands with Cu (II), Zn (II), Fe (II) and Co (II) salts.The chacterization was done through FT‐IR, NMR, UV‐visible, and elemental analysis. The X‐ray diffraction (XRD) patterns of [Cu(L1)(im)2(SO4)] demonstrated the crystalline morphology. In the FT‐IR spectra of the ligands, the characteristic frequencies corresponding to ν(C=N) (imine) and ν(C=S) (thiocarbonyl) were observed around 1650 and 1130 cm−1 respectively, which shifted upon complexation. In the 1H NMR spectra, the peak due to the NH proton was observed downfield, whereas that of ‐NH2 was observed comparatively upfield owing to its secondary amine nature. The molecular docking was performed against transforming growth beta (tgf‐β), protease of SARS‐CoV‐2 (Mpro) and aspartate kinase (Asp) kinase.The molecular simulation with the docked complex of [Zn(L2)(py)2(SO4)] and [Zn(L1)(PPh3)2(SO4)] with Asp kinase showed significant stability during the simulation time of 100 ns. The relative free energies of the simulated complexes were calculated with the molecular mechanics Poison‐Boltmann surface area (MM‐PBSA). The complexes were tested against ten bacterial strains and showed enhanced antibacterial activity than the ligands. [Cu(L1)(im)2(SO4)], [Zn(L1)(im)2(SO4)], [Fe(L1)(im)2(SO4)] and [Co(L1)(im)2(Cl2)] were found to be active against E.coli. [ABSTRACT FROM AUTHOR]

The medication bromhexine (BHX) is well‐known for its unique properties and therapeutic advantages, with prospective uses in the prevention and treatment of cancer growth and bacterial infections. The current research describes the synthesis of a unique series of mixed ligand complexes of Cr(III), Fe(III), Ni(II), Mn(II), Cu(II), Co(II), Zn(II), and Cd(II) produced from BHX (1ry ligand) and 1,10‐phenanthroline (Phen; 2ry ligand) and distinguished by spectral. The two ligands' potential for coordination with metal ions has been suggested in view of chemical analysis and spectral (1H‐nuclear magnetic resonance, ultraviolet–visible, and mass spectrometry) and thermal studies. BHX and Phen are neutrally bidentately coupled to the metal ions, according to infrared spectral study. The general formula of [M(BHX)(Phen)(H2O)n.Clm] was suggested using the molar conductivity, elemental analyses, and thermal information of the complexes that were produced. Where M = Fe(III) (n = y = 2, m = 0, and x = 3), Co(II) (n = x = 2, m = 0, and y = 3), Ni(II) (n = x = 2, m = 0, and y = 6), and Cd(II) (n = x = y = 2 and m = 0) with an octahedral geometry was proposed. Thermal analyses revealed that the complexes lost anionic part and organic ligands in continual changes after first losing water molecules of hydration. Compared with their parent BHX ligand, the mixed ligand complexes demonstrated promising microbiological activities against a variety of bacterial species, including Gram‐positive bacteria (Bacillus subtilis and Staphylococcus aureus) and Gram‐negative bacteria (Escherichia coli and Pseudomonas aeruginosa). According to the results, mixed ligand complexes are more efficient than the parent BHX and Phen ligands. The complexes moderately inhibit the development of the MCF‐7 antibreast cancer cell line. The chemistry of the linking energy, H‐bond, and hydrophobic interactions of the BHX ligand and its mixed Cu(II) complex with Phen are revealed by molecular docking investigations with the crystal structure of S. aureus nucleoside (PDB: 3Q8U) and human prostate‐specific antigen (PDB: 3QUM). [ABSTRACT FROM AUTHOR]

In this paper, a known mixed-ligand MOF {[Co2(TZMB)2(1,4-bib)0.5(H2O)2]·(H2O)2}n (compound 1) was reproduced, and its potential application potential was explored. It was found that compound 1 had high photocatalytic activity for CO2 reduction. After 12 h of illumination, the formation rate of CO, which is the product of CO2 reduction by compound 1, reached 3012.5 μmol/g/h. At the same time, compound 1 has a good antibacterial effect on Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Candida albicans (C. albicans), which has potential research value in the medical field. In addition, compound 1 can effectively remove Congo Red from aqueous solutions and achieve the separation of Congo red from mixed dye solutions. [ABSTRACT FROM AUTHOR]

Two new coordination polymers [Zn(L)(Bpa)·H2O]n (I) and [Zn(L)(Bip)]n (II) (H2L is 4‑hydroxyisophthalic acid, Bpa is 1,2-bis(4-pyridyl)ethane, Bip is 3,5-bis(imidazole-1-yl)pyridine) have been prepared and characterized by element analysis, powder X-ray diffraction, and single-crystal X-ray diffraction (CCDC nos. 2073592 (I), 2073594 (II)). The single crystal X-ray diffraction studies reveal that compound I is a 1D chain structure, in which zinc(II) is four-coordinated with a tetrahedral geometry. Complex II is a 2D layer structure, in which zinc(II) is four-coordinated. Complexes I and II are further extended into three-dimensional supramolecular network via hydrogen bonds and π···π interactions. The solid-state luminescent properties of compounds I and II have been investigated. [ABSTRACT FROM AUTHOR]

In this study, new mixed ligand Cu(II), Ni(II) and Pd(II) metal complexes were synthesized and characterized by NMR (for ligand), UV‐Vis, elemental analysis, FT‐IR, molar conductivity techniques. While the octahedral structure is recommended for Cu(II) and Ni(II) complexes, the square plane structure is recommended for the Pd(II) complex. The compounds lack conductivity traits indicating their non‐electrolyte nature in solution. Photoluminescence properties of the synthesized mixed ligand complexes were investigated. These three complexes showed emission bands when excited at their maximum absorbances. The excitation/emission bands of the Pd(II) complex shifted to higher (red) wavelengths when compared to the Cu(II) and Ni(II) complexes. The Pd(II) complex showed the Stokes shift of 26 nm. These metal complexes were screened for their anticancer activities against the colon cancer (DLD‐1) and lung cancer (A549) cell lines. The results show that these complexes have antiproliferative activity. In particular, two of the complexes (Pd(II) and Cu(II)) were found to have a higher cytotoxic effect than the positive control drug cisplatin with low IC50 values. [ABSTRACT FROM AUTHOR]

The current manuscript summarizes the insect toxicology and entomological efficacy of some newly synthesized mixed ligand complexes of Zinc against Spodoptera litura and Tetranychus sp. The results clearly indicate them as potential insecticidal agents. [ABSTRACT FROM AUTHOR]

[Display omitted] • The crystal structure of new mononuclear, mixed-ligand Co(II) complex is determined. • The maximum adsorption capacity of the complex reached 194.4 mg/g for Rhodamine B dye. • The plausible mechanism is electrostatic interaction, hydrogen bonding, and π-π interaction. • The kinetic study investigation provided, Q e = 207.3 mg/g. A new mixed-ligand cobalt complex with the general formula [Co(H 2 O)(teaH 3)(4-NBA)]·(4-NBA)·H 2 O (1), where (teaH 3 = triethanolamine and 4-NBA = 4-nitrobenzoate), has been successfully synthesized and characterized. In this complex, triethanolamine acts as a tetradentate ligand and the 4-NBA act as monodentate ligands. The cobalt metal ion in the complex has a coordination number of 6 with a slightly distorted octahedral geometry. Furthermore, some intramolecular and intermolecular interactions have been observed in 1. Moreover, the kinetic studies on the rate of adsorption confirm that the Pseudo Second Order model accurately predicted the absorption of RhB by the complex. The higher R-squared value and the close agreement between the calculated (Q e = 207.3 mg/g) and experimental (194.4 mg/g) values indicate a satisfactory match. The hydrogen bonding interactions and other weaker electrostatic interactions between the complex and the RhB molecule enhance this adsorption. [ABSTRACT FROM AUTHOR]

In this work, a sulfonated UiO-66 was synthesized and modified with a mixed ligand strategy using 2-amino terephthalic acid as a second linker. The X-ray diffraction (XRD) diffractogram shows a transition from an amorphous to a crystalline pattern with the addition of a second linker. The Fourier transforms infrared spectroscopy spectra show the presence of new peaks at 1255, 1382, and 1426 cm−1, which refer to N-H and C-N stretching. All the mixed ligand samples showed stable thermal stability as the pristine UiO-66-SO 3 H sample. The field emission scanning electron microscopy analysis also showed a morphological change from a round-like shape (UiO-66-SO 3 H) to a triangular-based pyramid shape (UiO-66-SO 3 H-NH 2 -0.85). The nitrogen physisorption analyses showed a significant increase in the BET surface area of UiO-66-SO 3 H-NH 2 -0.85 (706 m2/g) from UiO-66-SO 3 H (16 m2/g). The CO 2 -TPD results demonstrated that the greater formation of medium basic sites (monodentate carbonate and bidentate carbonate species) is due to the increase in the amount of the second linker. Furthermore, the UiO-66-SO 3 H-NH 2 -0.85 showed CO 2 adsorption of 2.17 mmol/g, five times higher than UiO-66-SO 3 H (0.43 mmol/g). Both samples also showed excellent recyclability up to ten cycles. After being reused for ten cycles, the sample preserved the characteristics of the XRD pattern and crystallinity, functional groups, and thermal stability. For the water and pH stability studies, UiO-66-SO 3 H and UiO-66-SO 3 H-NH 2 -0.85 maintained the original XRD patterns, a high BET surface area, and good CO 2 adsorption in water and acid environments. [Display omitted] • Introducing the amino group as a second linker into UiO-66-SO 3 H is an efficient approach. • The highest CO 2 adsorption was observed on UiO-66-SO 3 H-NH 2 -0.85 of 2.17 mmol/g at 25 ˚C and 1 atm. • UiO-66-SO 3 H and UiO-66-SO 3 H-NH 2 -0.85 maintain the recyclability for up to ten cycles. • BET surface area and polar functional groups played important roles in CO 2 adsorption performance. • UiO-66-SO 3 H and UiO-66-SO 3 H-NH 2 -0.85 showed good water and chemical stability. [ABSTRACT FROM AUTHOR]

[Display omitted] • A novel mixed imidazole ligand MIL-88A was proposed and prepared for the first time. • The photocatalyst revealed significantly smaller particle size and greatly improved photocatalytic capacity. • 100% decomposition of 100 ppm AR1 dye was achieved within 45 min of irradiation with the assistance of a trace amount of H 2 O 2. • A dye removal rate of 99.98% was maintained after five cycles. • Photo-generated h+ was the main oxidizing specie in the photocatalytic reaction. In this study, we fabricated MIL-88A metal–organic frameworks with excellent physicochemical properties using mixed organic ligands. In addition, we investigated the effects of different iron precursors on the physicochemical properties of the as-prepared MIL-88A samples. We determined that the difference between the dissociation rates of the metal ions of different iron precursors affected the crystallization rate of MIL-88A, which effectively decreased particle size, causing an increase in the adsorption capacity of MIL-88A and significantly improving its photocatalytic activity. Two organic ligands: 2-methylimidazole and fumaric acid, were mixed, and the formed dihydrate affected the crystallization rate of MIL-88A; moreover, the as-fabricated MIL-88A presented small particle size and high oxidation potential. The as-prepared mixed organic ligand MIL-88A removed 96.42% of AR1 dye from an AR1 dye solution with a concentration of 20 mg/L after 2 h of irradiation. Furthermore, an AR1 dye removal of 100% was achieved after only 45 min of irradiation using a 100 mg/L AR1 dye solution in the presence of trace H 2 O 2. The decomposition efficiency of MIL-88A did not decrease after five removal cycles, and this was attributed to the excellent decomposition efficiency of MIL-88A with mixed organic ligands, which was ascribed to its remarkable adsorption capacity and high oxidation potential. Strong oxidizing hydroxyl radicals were generated via a photo-Fenton reaction to improve the oxidative power of MIL-88A, and pollutants were decomposed without generating residues. We believe that these findings can be used to significantly expand the application of MIL-88A in photocatalysis research. [ABSTRACT FROM AUTHOR]

In this paper, a known mixed-ligand MOF {[Co2(TZMB)2(1,4-bib)0.5(H2O)2]·(H2O)2}n (compound 1) was reproduced, and its potential application potential was explored. It was found that compound 1 had high photocatalytic activity for CO2 reduction. After 12 h of illumination, the formation rate of CO, which is the product of CO2 reduction by compound 1, reached 3012.5 μmol/g/h. At the same time, compound 1 has a good antibacterial effect on Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Candida albicans (C. albicans), which has potential research value in the medical field. In addition, compound 1 can effectively remove Congo Red from aqueous solutions and achieve the separation of Congo red from mixed dye solutions.

Constructing metal–organic frameworks (MOFs) with high volatile organic compounds (VOCs) adsorption capacity and excellent water resistance remain challenging. Herein, a monocarboxylic acid‐assisted mixed ligands strategy was designed to synthesize a novel fluorinated MOFs, MIL‐53 (Al). The monocarboxylic acid promoted crystallization and produced abundant crystal defects, which increased pore volume. Moreover, the competitive coordination between tetrafluoroterephthalic acid and 1,4‐dicarboxybenzene was moderated by monocarboxylic modulators, significantly improving the hydrophobicity. The toluene uptake of the optimal sample reached 254.85 mg g−1 under humid conditions, increased by 33.56 % of MIL‐53(Al), and the QWet/QDry (the ratio of adsorption quality under wet to adsorption quality under dry) was 0.92, remarkably surpassing that of origin MIL‐53 (0.72). The recycle experiment showed superior reusability with no performance degradation after 10 recycle under RH=50 % (relative humidity). The adsorptive kinetic and thermodynamic analysis proves that the adsorption process is controlled by surface mono‐layer adsorption and pore diffusion. The fluorine group affects the internal diffusion, which weakens the transfer rate. This strategy opens a new prospect of obtaining hierarchical functional MOFs for meeting the VOCs uptake under the practical application. [ABSTRACT FROM AUTHOR]

Synthesis of some ternary complexes with isatin (ISA) as primary ligand and N,N,N,N‐tetramethyl ethylene diamine (TMEDA) as secondary ligand with a series of metal ions (M) Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) is presented. IR, elemental analysis, melting point, molar conductance, mass and thermal analysis were applied to characterize the prepared compounds. Conductometry measurements reveal that all complexes are non‐electrolytes except Cr(III), Mn(II), Fe(III) and Co(II) complexes. In the light of magnetic and solid reflectance techniques, all prepared complexes were suggested in an octahedral geometry. ESR study of Cu(II) complex prove its octahedral geometry. The mixed ligand complexes were found to have the formulae [M(ISA)(TMEDA)Cl2] where M=Ni(II), Cu(II) and Zn(II); [M(ISA)(TMEDA)Cl2]Cln.xH2O in case of M=Cr(III), Fe(III) and Cd(II) (where n=l, x=0 for Cr(III), n=l, x=0 for Fe(III) and n=0, x=2 for Cd(II) and [M(ISA)(TMEDA)Cl(H2O)]Cl in case of M=Mn(II) and Co(II). Antimicrobial activity of some complexes are higher than parent ligands. Molecular docking study confirmed the importance of Cu(II), Ni(II) and Cr(III) complexes as they have the highest interaction with the receptors of crystal structure of S.aureus nucleoside (PDB ID: 3Q8U), E. coli (PDB: 3T88) and protein phosphatase (PPZl) of C. albicans (PDB: 5JPE) with minimum binding energy of −2l.5, −7.2 and −45.6 kcal/mol, respectively. [ABSTRACT FROM AUTHOR]

A Cu(II) coordination polymer with the composition of [Cu2(L)2(4,4ʹ-bipy)2]n·2 n(ClO4) (1, HL = 4-methyl-L-phenylalanine and 4,4ʹ-bipy is 4,4ʹ-bipyridine), was successfully obtained by the reaction of the mixed ligand of HL and 4,4ʹ-bipy with Cu(ClO4)2 · 6H2O under solvothermal condition. The as-synthesized compound not only has high thermal stability until 275°C but also excellent photocatalytic activity for the methyl blue solution degradation under the irradiation of ultraviolet light. Furthermore, the compound’s treatment activity on the diabetes was determined and its relevant mechanism was also studied. The cytotoxicity or hemolysis toxicity (HC50) of the synthesized compound was also evaluated in this research.

A Cu(II) coordination polymer with the composition of [Cu2(L)2(4,4ʹ-bipy)2]n·2 n(ClO4) (1, HL = 4-methyl-L-phenylalanine and 4,4ʹ-bipy is 4,4ʹ-bipyridine), was successfully obtained by the reaction of the mixed ligand of HL and 4,4ʹ-bipy with Cu(ClO4)2 · 6H2O under solvothermal condition. The as-synthesized compound not only has high thermal stability until 275°C but also excellent photocatalytic activity for the methyl blue solution degradation under the irradiation of ultraviolet light. Furthermore, the compound's treatment activity on the diabetes was determined and its relevant mechanism was also studied. The cytotoxicity or hemolysis toxicity (HC50) of the synthesized compound was also evaluated in this research. [ABSTRACT FROM AUTHOR]

Two new mixed-ligand coordination polymers (CPs) with the chemical formulae of [Co(L)(phen)]n (1, phen = 1,10-phenanthroline and [Co(L)(4,4′-bipy)4·2H2O]n (2, 4,4′-bipy = 4,4′-bipyridine) have been successfully synthesized by the solvothermal reaction of 1,4-bis(3-carboxylbenzyl)piperazine acid (H2L) and different N-donor co-ligands with Co(II) salt. In the biological function study, the treatment effect of compounds 1 and 2 on the Alzheimer's disease (AD) was evaluated and the detail mechanism was explored in this research. Firstly, the AD animal model was constructed, and the content of the Amyloid (Aβ) in the brain after compounds 1 and 2 treatment was detected. Then the protective activity of compounds 1 and 2 on neurons was evaluated after Aβ stimulation. Two new mixed-ligand coordination polymers have been synthesized. In the biological function study, the treatment effect of compounds 1 and 2 on the Alzheimer's disease (AD) was evaluated and the detail mechanism was explored in this research. Firstly, the AD animal model was constructed, and the content of the Amyloid (Aβ) in the brain after compounds 1 and 2 treatment was detected. Then the protective activity of compounds 1 and 2 on neurons was evaluated after Aβ stimulation. [ABSTRACT FROM AUTHOR]

Ofloxacin is a quinolone antibiotic. It is considered an efficient antibacterial drug with a broad spectrum of activity against anaerobic and aerobic bacteria. Moreover, it shows strong antibacterial activity in vitro against many bacteria species by inhibiting their DNA-gyrase. In this study, the synthesis, physicochemical and spectroscopic characterization of Cobalt (II) metal complex, with ofloxacin as the primary ligand and ascorbic acid as the secondary ligand were achieved. The complex was prepared by using the reflux method for four hours in methanol. The complex, with the molecular formula [Co(Ofl)(Asc)], was characterized by its color, solubility, melting point, FTIR, UV/Visible, 1H NMR, and 13C NMR spectroscopy. The color and the melting point suggested that complexation occurred. The Fourier Transform Infrared data for both the primary ligand (Ofl) and the secondary ligand (Asc) acted as tridentate ligands. Ofl coordinated with the Co(II) metal ion via the two carbonyl oxygen atoms and the oxygen atom of the hydroxyl group, whereas Asc coordinated with the metal through the carbonyl and enolic C-2 and C-3 hydroxyl groups. Electronic data suggested octahedral geometry for the complex. The ligands and the novel Co (II) complex were tested for in vitro antibacterial activity against gram-negative and gram-positive bacterial species using the filter paper disc agar diffusion method. Significant antibacterial activities were observed against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Candida albicans for the complex as compared to the ligands. This research will aid in the development of more potent drugs that are resistant to organisms. Keywords: antibacterial activity, ascorbic acid, cobalt (II), mixed ligand, ofloxacin. Copyright (c) The Authors

2-Aminobenzotiyazol ile bazı organik bileşiklerin [β-pikolin, γ-pikolin, isokinolin, asetilaseton, o-hidroksiasetofenon, 1,2-etilendiamin, piperazin, N, N'-bis(4-antipirilmetil)piperazin, N,N'-tetra(4-antipirilmetil)-1,2-diaminoetan, N,N'-bis(4-antipirilmetil) piperazin, N, N'-tetra(4-antipirilmetil)-1,2-diaminoetan, ftalamid, malonamid, benzilaseton, tetrametilen sulfoksit, katekol, p-klorofenoksiasetik asit, 7-oksobisiklo[2.2.1] heptan-2,3-dikarboksilik asit, 2,2’-bipridin, 1.10-fenantrolin, propanoik asit, fenoksiasetik, 2-imino-3-allilbenzotiyazol, sakarin, trifenilfosfin, trifloroasetik asit, adipik asit, 1,4-benzendikarboksilik asit, süksinik asit, formik asit, pikrik asit, amino asit, p-formilfenoksiasetik asit ve 2,6-piridindikarboksilik asit] karışık ligandlı metal komplekslerinin (M = Mn, Fe, Co, Ni, Cu, Zn, Ag, Au, Ru, Os, Ir, Pd, Rh, U, Eu ve Tb) yapıları ve biyolojik özelliklerini anlatan çalışmalar literatürde gözlenmiştir. Bu bileşiklerde 2-aminobenzotiyazol metale tiyazol halkasının N ve/veya S ve/veya animo grubundan bağlanmakta ya da tamamlayıcı iyon şeklinde yapıda yer almaktadır. Bu komplekslerinin antibakteriyel, antikanser, antifungal, anti-inflamatuar, antitümör ve karbonik anhidraz inhibisyonu gibi biyolojik özellikleri bilinmektedir.

Two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L1)(bdc)](H2O)}n (1, L1 = 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene, H2bdc = terephthalic acid) and {[Co(L2)(bdc)](H2O)}n (2, L2 = 1,3-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene) have been successfully prepared by the solvothermal treatment of H2bdc and different N-donor co-ligands with Co(II) salt. In biological functional study, the treatment effect of compounds 1 and 2 on the ulcerative colitis (UC) was evaluated. Firstly, the ELISA assay was performed to reveal the changes of the inflammatory cytokines caused by compounds. Besides, the model of mice was established and the mice' body weight was measured and recorded at the 7th and 14th day after compounds treatment. [ABSTRACT FROM AUTHOR]

Mixed ligand Mn(II), Co(II), Ni(II), Cu (II), Zn(II), and Cd(II) complexes with (TMAP) Schiff base ligand and (8HQ) have been composition and analyzed. Diagnosis by, melting point, solubility, Electronic, mass and IRspectroscopic studies, conductivity elemental, thermoanalytical analysis displayed the forming of mononuclear complexes. Spectral studies results suggest an octahedral system or the metal (II) mixed complexes. The detainments of molar conductance of the mixed complexes in DMF coincide to electrolytic nature of the mixed complexes, consequently, these complexes could be subedited as [M(TMAP)(8Q)(H2O)]nX.yH2O (M=Co(II) and Cu(II) complexes(where n = 1, y = 0); [M(TMAP)(8Q)(H2O)]nX.yH2O (M = (where n = 1, y = 1 for Ni(II) complex and n = 1, y = 2 for Cd(II) complex) and [M(TMAP)(8Q)(H2O)]nX.yH2O (M = Mn(II) (n = y = 2) and Fe(III) (n = 3, y = 0)). On the principle of electronic spectra, magnetic moment studies, an octahedral structure has been designated for the metal complexes. Further parameters of the thermodynamic and kinetic for the various stages of decomposition were determined to utilize the Horowitz-Metzger and Coats-Redfern ways. Then, the ligand in rapprochement to metal complexes is tested for their anticancer and antimicrobial efficacy with breastic cancer cell line. The outcomes showed that the metal complexes are more active than the parent TMAP ligand but more active than (8HQ) free ligand. In these complexes, the metal ion chalets to the ligand through the azomethine linkage, (NH2) and imine(C=N) groups of trimethoprim drug. The outcomes of conductivity related that the complexes were all 1:1 electrolytes except Mn(II) and Zn(II) complexes are nonelectrolyte. The metal complexes were tested for their antimicrobial efficacies applying agar disc diffusion method and the outcomes related that they were active with bacteria pieces screened. [ABSTRACT FROM AUTHOR]

Two new mixed-ligand coordination polymers with the chemical formulae of {[Zn3(nbta)2(bpfp)2(H2O)2](H2O)2}n (1, H3nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bpfp = bis(4-pyridylformyl)piperazine) and {[Cd3(nbta)1.5(bib)2(H2O)](H2O)}n (2, bib= 4,4'-bis((1H-imidazol-1-yl)methyl)−1,1'-biphenyl) have been successfully synthesized by the solvothermal reaction of 5-nitro-1,2,3-benzenetricarboxylic acid, and different N-donor co-ligand. All compounds were adequately characterized, and their structures were verified by single-crystal X-ray diffraction along with the elemental analysis. Furthermore, the treatment effect of compounds 1 and 2 on the acute adnexitis was evaluated in the biological study. Firstly, the RT-PCR was performed to detect the inhibitory effect of the compounds on the survival gene in the Staphylococcus aureus-fitZ. Then, the ELISA was conducted to measure the release level of the inflammatory cytokines. [ABSTRACT FROM AUTHOR]

Two new Co(II)-based coordination polymers {[Co(L)](DMF)}n (1, H2L = 5-(1H-imidazol-1-yl)isophthalic acid) and {[Co2(L)2(H2O)]·3H2O}n (2) are successfully synthesized by the hydrothermal or solvothermal method. The resulting single crystal X-ray diffraction studies demonstrate that complex 1 presents a 3D 3,6-connected framework with a binuclear Co(II) paddle-wheel cluster as the secondary building unit, while complex 2 displays a 3,3,4,8-connected 3D network structure with the a trinuclear linear Co3(CO2)6 cluster as the secondary building unit. The in vivo local anesthesia activity of compounds 1 and 2 is evaluated via the mice hot plate analgesic experiment. Then, the local content of acetylcholine in mice is measured by the ELISA assay. [ABSTRACT FROM AUTHOR]

Two new mixed-ligand coordination polymers with the chemical formulae {[Co(5-amipa)(bpe)]DMF}n (1, H2amipa = 5-aminoisophthalic acid, bpe = 1,2-bis(4-pyridyl)ethylene, DMF = dimethylformamide) and {[Co(5-amipa)(bpe)](DMA)}n (2, DMA = dimethylacetamide) are successfully synthesized by the solvothermal reaction of 5-aminoisophthalic acid and the N-donor 1,2-bis((4-pyridyl)ethylene) co-ligand with Co(II) salt in different solvent systems. All compounds are adequately characterized, and their structures are verified by single crystal X-ray diffraction along with the elemental analysis. Furthermore, the protective effect of compounds 1 and 2 on Parkinson disease is evaluated in the biological function section. Firstly, the ELISA detection is performed to estimate the dopamine content in the substantia nigra after treatment with the compounds. Then the open field test is finished to reflect the treatment ability of the compounds on the cognitive ability of mice. [ABSTRACT FROM AUTHOR]

Two coordination polymers named [Co(tib)(H2O)3]· ipa·2H2O (1, H2ipa = iso-phthalic acid) and [Cu3(tib)2(BTB)2]·DMF·2H2O (2, H3BTB = 4,4′,4′′-gbenzene-1,3,5-triyl-tribenzoic acid, DMF = N,N-dimethylformamide) were constructed using a solvothermal method by reaction of metal salts with the 1,3,5-tris(1-imidazolyl)benzene (tib) ligands and different carboxylate linkers as the co-ligands. The two complexes have been characterized by X-ray diffraction as well as the elemental analyses. Subsequently, the protective effect of compounds 1 and 2 on the acute lung injury and its related mechanism was explored. Firstly, the enzyme linked immunosorbent assay (ELISA) was performed to detect the release of the inflammatory cytokines. Then, the partial pressure of oxygen (PaO2) and the partial pressure of carbon dioxide (PaCO2) was measured with blood gas analysis. [ABSTRACT FROM AUTHOR]

In the current study, two new luminescent coordination polymers based on Zn(II) ions as nodes, {[Zn3(tcpb)2(bibp)2]·4dioxane·DMF·H2O}n (bibp = 4,4′-bis(imidazol-1-yl)biphenyl) and {[Zn(Htcpb)(4,4′-bpy)·(DMF)·(dioxane)0.5·(H2O)2]}n (4,4′-bpy = 4,4-bipyridine), were prepared from polycarboxylate ligand 1,3,5-tris(4-carbonylphenyloxy)benzene (H3tcpb) as well as different N-donor co-ligands. In addition, the luminescent sensing performance for {[Zn3(tcpb)2(bibp)2]·4dioxane·DMF·H2O}n was explored, which shows that it could behave as the sensor of acetylacetone (acac) containing high sensitivity and selectivity. Furthermore, the treatment effect of the compounds on optic neuritis was evaluated. Firstly, the relative expression of the inflammatory genes mapk and akt was measured by RT-PCR. Besides, the release for the TNF-α and IL-1β into plasma was measured by ELISA detection kit. [ABSTRACT FROM AUTHOR]

By applying the mixed‐ligand approach, a new Cu(II)‐containing coordination polymer [Cu4(L)4(4,4′‐bpy)(H2O)2]·3H2O (1) was successfully prepared through hydrothermal method using linear 4,4′‐bipyridine (4,4′‐bpy) and the V‐shape carboxylate ligand 4,4′‐(phenylazanediyl)dibenzoic acid (H2L). The as‐prepared complex 1 was determined by single‐crystal X‐ray crystallography and elemental analysis. Furthermore, we use the grinding method to prepare the samples of complex 1 in the nanoscale. In this research, the CCK‐8 was performed first to detect the inhibitory activity of complex 1 on J82 bladder cancer cell viability. The apoptotic effect of complex 1 on J82 cancer cells was evaluated by Annexin V‐FITC/PI staining. The reactive oxygen species (ROS) was also detected by detection kit in this study after complex 1 treatment. Beyond the experimental results, the molecular docking technique has been used to probe the anticancer activity that originated at the molecular level. [ABSTRACT FROM AUTHOR]

In this work, by employment of a rod-like ligand 4,4′-bis(imidazol-1-yl)-biphenyl (bibp) as the building block, a new Zn(II)-containing coordination polymer with the chemical formula of {[Zn2(HCO2)3(bibp)2](HCO2)3·2H2O} (1) has been successfully prepared by the reaction of Zn(II) salts and the bibp ligand in a mixed solvent of DMF and water. Furthermore, we use the grinding method to downsize the complex 1 to nano-region. To evaluate the anti-cancer activity of the synthetic compound, the Annexin V-FITC/PI assay in flow cytometry was performed to detect the apoptosis of human osteosarcoma cells, and the following mechanism exploration was performed by DCFH-DA detection assay for ROS measurement. [ABSTRACT FROM AUTHOR]

The solvothermal reaction of Cd(NO3)2·4H2O with different donor ligands afforded two new Cd(II)-based coordination polymers [Cd(Hcia)(btz)]n (1, H3cia = 5-(4-carboxyphenoxy)isophthalic acid, btz = 4,4'-bi(1,2,4-triazole)) and {[Cd(2,2-bpy)(NO3)2(H2O)](DMA)}n (2, 2,2'-bpy = 2,2'-bipyridine). Complex 1 shows a 3 D 2-fold interpenetrated network based on 1 D infinite [–btz–Cd–btz–] chains, and complex 2 shows 1 D chain-like network based on the 2,2'-bpy chelating Cd centers extended by the NO3- ions. Furthermore, the CCK-8 assay and Annexin V-FITC/PI detection was performed to evaluate the anti-cancer activity of the two complexes against the Hey ovarian cancer cell lines. Western blot was conducted for the mechanism evaluation of the complexes. [ABSTRACT FROM AUTHOR]

Mixed ligand approach has been successfully applied to design coordination polymers with diversiform architectures. In this study, two novel mixed-ligand Zn(II)-based coordination polymers [Zn(bdc)(bib)](H2O)3 (1, H2bdc = 1,4-dicarboxybenzene, bib = 1,3-bis(imidazol-1-yl)benzene) and [Zn(NH2-bdc)(bib)](H2O)2 (2, NH2-H2bdc = 2-amino-1,4-dicarboxybenzene) have been successfully prepared based on zinc nitrate, N-containing ligand and linear carboxylate ligand at the same hydrothermal condition. The anti-viability of compounds 1 and 2 against SMMC-7721 liver cancer cells was assessed with CCK-8 detection kit. Besides, the cell apoptosis and ROS detection experiments were also performed to study the related mechanism about the anticancer activity of compounds 1 and 2. [ABSTRACT FROM AUTHOR]

In this work, a new Ni(II)-based coordination polymer (CP) with the chemical formula of {[(Ni)2(L1)(L2)(H2O)2](DMF)2}n (1, H4L1 = 5-((3,5-dicarboxybenzyl)oxy)isophthalic acid, L2 = 2,4,6-tri(pyridin-4-yl)-1,3,5-triazine) has been successfully prepared by reaction of Ni(NO3)2·6H2O with the 5-((3,5-dicarboxybenzyl)oxy)isophthalic acid and tri(pyridin-4-yl)-1,3,5-triazine in a mixed solvent of DMF and water. Furthermore, nano-sized complex 1 was prepared via using the refluxing method, and the scannig electron microscopy confirmed nano-sized particles and their homogeneous distribution. In the biological functional section, the treatment activity of nano 1 in the type 2 diabetes was evaluated. Firstly, the liver cells HepG2 were treated with nano 1, and the relative expression of pck and mapk was detected by RT-PCR. Then, the western blot was performed to detect the expression level of PKC and MAPK proteins. [ABSTRACT FROM AUTHOR]

The mixed ligand complexes involving Fe(II), Co(II) and Ni(II) ions, Schiff base 4-benzylimino-2,3-dimethyl-l-phenylpyrazal-5-one (L1) and L-lysine (Lys) were synthesized. The complexes were characterized on the basis of their elemental analysis, conductivity measurements, FT-IR, MS,¹ H-NMR and 13C-NMR spectral studies. All the synthesized complexes were subjected to simultaneous thermogravimetric analysis to study their decomposition mechanism and thermal stability. The mixed ligand complexes were screened against some strains of bacteria and fungi to study their antimicrobial activity. The complexes were found to be non-electrolytes and possessed octahedral geometry. The results showed that the metal complexes possessed better antimicrobial activity than the free ligands. [ABSTRACT FROM AUTHOR]

By introducing functional groups into the isophthalate ligand to decorate the pore of the MOFs, gas adsorption and separation performance can be tunable. In this paper, two isostructural 2D Co-MOFs, [Co(5-MIA)(bpy)]·H 2 O (1) and [Co(5-EIA)(bpy)]·H 2 O (2) (5-H 2 MIA = 5-methoxyl-isophthalic acid; 5-H 2 EIA = 5-ethyoxyl-isophthalic acid; bpy = 4,4′-bipyridine), with different functionalized pore surfaces and channel sizes were designed and constructed. The structures and performance of the two Co-MOFs were analyzed by SCXRD, PXRD, IR, TGA, and gas sorption (CO 2 , C 2 H 2 , CH 4 , CO, and N 2). Attributed to the methoxyl of isophthalate skeleton, 1a (activated 1) shows enhanced CO 2 uptake over other gases. In spite of decreased pore sizes (3.49 Å) compared with 2a (4.38 Å), the CO 2 uptake of 1a (43.41 cm3 g−1) is larger than that of 2a (22.39 cm3 g−1) at 298 K and 100 kPa. Compound 1 incorporates methoxyl groups into the narrow channel, and exhibits the cooperative effect of CO 2 -preferential due to adsorbent-adsorbate coactions and size sieving. GCMC simulation has been used to explore the adsorption coactions of CO 2 and 1 , and the results confirmed that the methoxyl groups in the channel are the main binding sites of CO 2. At ambient temperature and 100 kPa, the IAST selectivities of CO 2 /C 2 H 2 (1:1), CO 2 /CH 4 (1:1), C 2 H 2 /CH 4 (1:1), CO 2 /CO (1:2) and CO 2 /N 2 (15:85) on 1a were 2.6, 39.3, 13.3, 282 and 1433, respectively. The easy activation and regeneration, excellent thermal and humidity stability, and good reusability, make 1 a hopeful adsorbent for adsorption and separation of CO 2. By introducing functional groups into the isophthalate ligand to decorate the pore of the MOFs, gas adsorption and separation performance can be tunable. Two isostructural 2D Co-MOFs with different functionalized pore surfaces and channel sizes were constructed and show different C 2 H 2 /CH 4 and C 2 H 2 /CO 2 gas separation properties. [Display omitted] • Title compound represent the first example of 3D MOF based on 5-H 2 MIA and bpy. • 1a (activated 1) shows enhanced CO 2 uptake over C 2 H 2 , CH 4 , CO and N 2. • 1a shows an excellent reuse performance. [ABSTRACT FROM AUTHOR]

Two new coordination polymers {[Zn(HL)(HBpp)] · H2O}n (I) and [Cd(HL)(HBpe)]n (II) (H4L = 5-(2,3-dicarboxy phenoxy) isophthalic acid, Bpp = 1,3-bis(4-pyridyl)propane, Bpe = 1,2-bis(4-pyridyl)ethylene) were prepared and characterize by element analysis, powder XRD and single crystal X-ray diffraction (CCDC nos. 1836060 (I), 1844999 (II)). The single-crystal X-ray diffractions reveal that the complex I is a 2D carboxylate layer with the HBpp suspension arms, in which the zinc(II) is four-coordinated with a tetrahedral geometry. Compound II is a 1D Cd(II)-carboxylate chains, in which the cadmium(II) is seven-coordinated with a distorted pentagonal bipyramidal geometry. Complexes I and II are further extended into three-dimensional supramolecular framework via hydrogen bonds. The solid state luminescent properties of compounds I and II have been investigated. [ABSTRACT FROM AUTHOR]

I–III–VI quantum dots (QDs) play an important role in visible-light-driven photocatalysis due to their unique optical properties and widely tunable bandgap. However, these materials suffer from rich defect states and high charge carrier recombination. In this work, a facile mixed-ligand method was developed for the manipulation of the optical and photocatalytic properties of multinary Ag–In–Zn–S QDs by introducing 3-mecaptopropionic acid (MPA) into the l-cysteine (Cys) capped QDs system during synthesis. The effect and mechanism of MPA addition was systematically investigated. With the increase of MPA/Cys, the photoluminescence (PL) quantum yield (QY) of the QDs shows an obvious increase at the first stage (MPA/Cys < 5:5), whereas the particle size and UV–Vis absorption remain almost unchanged. Photocatalytic properties of QDs shows similar trend as PL QY with the increase of MPA/Cys, where the hydrogen production rate was doubled with MPA/Cys = 5:5. With ascorbic acid (AA) as the sacrificial reagent, the MPA/Cys capped QDs gave a hydrogen production rate as high as 6.64 mmol g−1 h−1, which is comparable to the state-of-the-art results but without any cocatalyst, indicating the fascination of the simple mixed-ligand method. Further mechanism study indicates that the introduced MPA resulted in dramatic increase of the PL lifetime and the reduction of nonradiative decay, which can be ascribed to the strong passivation effect of MPA. The MPA/Cys capped QDs also show compressed charge recombination as indicated in electrochemical impedance spectra, slightly more negative ζ-potential and reduced hydrated particle radius, which may also contribute to the improved charge transfer for photocatalysis. Our method provides a super simple strategy for the defect manipulation of the Ag–In–Zn–S QDs without the sacrifice of charge transfer, which could be a useful guideline for efficient QDs-based visible-active photocatalysts. Mixed-ligand-modified Ag–In–Zn–S quantum dots with improved hydrogen production were prepared. [ABSTRACT FROM AUTHOR]

The purpose of this investigation is to synthesize mixed ligand complexes of first, second, and third row transition metals including Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II), Zn (II), Cd (II) and Pb (II) with L1 = 8‐hydroxyquinoline and L2 = DL‐methionine. Newly synthesized metal complexes have been characterized by UV‐Visible, IR, mass spectrometry and micro‐analytical techniques such as conductance measurement, elemental analysis, and melting point. Synthetic mixed complexes were also screened for antioxidant activity. Transition metals based complexes of mixed ligands containing O/N donor atoms were synthesized and characterized by UV‐Visible, IR, mass spectrometry and micro‐analytical techniques. The synthetic complexes were then screened for antioxidant activity. [ABSTRACT FROM AUTHOR]

Carbon dioxide (CO2) emissions from fossil fuels cause air pollution and lead to adverse impact on environment. To achieve low-carbon economy, capturing CO2 in the environment by methods like physisorption on zeolitic imidazolate frameworks (ZIFs) and other zeolite materials has gained attention due to their pore tunability and adsorption efficiency. Exploring the efficacy of the ZIF in adsorbing CO2, we report a rapid and convenient protocol for the synthesis of novel hybrid monometallic and bimetallic Zn/Co/Co-Zn-based ZIFs at room temperature, and we evaluate their CO2 capture capacity. ZIFs with varying Co:Zn ratio were synthesized by altering the content of Co and Zn precursors. The CO2 uptake capacity of mono/bimetallic Zn-Co ZIFs was studied at 298 K and attains the highest CO2 uptake of 65.50 cm3/g. This rapid room temperature protocol is highly efficient for the synthesis of mono/bimetallic ZIF-CO2 adsorbents. [ABSTRACT FROM AUTHOR]

Abstract The new series of divalent metal complexes [M(ox)(thy) 2 ]; M = Cd2+, Ni2+, Mn2+, Fe2+, Cu2+ and Zn2+, with mixed ligands oxalato (ox) and theophylline (thy) were prepared and characterized by molar conductance, FT-IR, UV–visible, 1H and 13C NMR and X-ray structure analysis. The crystal structure including the positions of the Zn (II) complex was determined by powder diffraction analysis using the FOX program. In the structure of zinc complex, the zinc (II) cations are octahedrally coordinated by two terminals N-bonding for theophylline ligand and by the O atoms of two oxalato bidentate ligand, resulting in discrete and slightly distorted octahedral complex. This complex was crystallized in the monoclinic system (C1 2/c1) space group and the unit cell parameters are a = 11.8364(1)Å, b = 4.5200(1)Å, c = 9.9942(1)Å with β (°) = 126.4770(2)°. The antimicrobial activity of the complexes was studied and the results of their tests show that the metal (II) complexes are more effective against several of bacterial and fungal strains. Graphical abstract Image Highlights • Six new complexes of general formula:[M (ox)(thy) 2 ] were synthesized. • The characterization of the synthesized complexes was investigated. • The octahedral structure of the obtained complexes was checked. • The antibacterial activity of the complexes was tested. [ABSTRACT FROM AUTHOR]

Abstract Two novel mixed-ligand complexes of lead(II), [Pb(Cup) 2 (Phen)] 2 ](DPE) (1) and [Pb(Cup)(ONO 2)(Phen)] (2) (Cup = cupferronato, Phen = 1,10-phenanthroline, and DPE = 1,2-di(4-pyridyl)ethylene), were synthesized in the presence of common bridging ligands which are usually used in synthesis of lead(II) coordination polymers as well as utilization of Cup and Phen as O,O′- and N,N′- chelates, respectively. Structural features of 1 and 2 in solution were investigated by 1H and 13C NMR experiments. The accurate assignment of these signals was inferred from a series of 1H–1H COSY, 1H–13C HSQC, and 1H–13C HMBC spectra. The solid-state structures of 1 and 2 were also investigated via single crystal XRD. By considering the obtained structural parameters, the coordination of 1 is hemidirected while 2 is suggested to be holodirectional. Additionally, complex 1 consist of dimers which are further associated via π-π stacking to a one-dimensional coordination polymer while complex 2 forming a step-like one-dimensional chain by an intermolecular interaction between each molecule and two nitrato groups of the two adjacent molecules. Both complexes showed significant antibacterial and antifungal characteristics in disc diffusion tests and they could be considered as new potent antimicrobial material. Graphical abstract Image 1 Highlights • Two novel mixed-ligand complexes of lead(II) were prepared. • The structures in solution were investigated by different NMR spectroscopies. • The molecular structures showed hemidirected and holodirected coordinations. • 1 consists of associated dimers via π-π stacking and forms 1D coordination polymer. • Complex 2 forms a step-like one-dimensional chain. [ABSTRACT FROM AUTHOR]

تم تحضير معقدات جديدة للنحاس تتضمن ليكندات مختلطة صيغتها العامة [Cu(4-Hydrpipdtc)2L2] و [Cu(4-methylpipdtc)2L2] حيث ان (4-Hydrpipdtc), و(4-methylpipdtc) = 4-hydroxylpiperidinedithiocarbamate و 4-methylpiperidinedithiocarbamate على التوالي و L = 4-picoline ,luitidine ,en ,(1-10)phen,PPh3وشخصت المعقدات المحضرة بواسطة تحليل العناصر وقياسات التوصيلية واطياف الاشعة تحت الحمراء والمرئية والفوق البنفسجية وقياسات الحساسية المغناطيسية ومن النتائج تم اقتراح الشكل المربع المستوي للمعقد بس داي ثايوكاربميت نحاس (II) والشكل ثماني السطوح للمعقدات الاخرى.

The mixed ligand complexes of the kind [M(L1) (L2)] where M= Pt(II), Pd(II).L1 = primary ligand ethyl-α-isonitrosoacetoacetate derived from reaction between ethyl acetoacetate, acetic acid and sodium nitrite and L2=secondary ligand para-phenyldiamine (PPD) are synthesized. All the prepared complexes were identified and confirmed by elemental analysis, molar conductance measurements, and infrared electronic absorption. Their complexes has been made based on elemental analysis, molar conductivity, UV-Vis, FT-IR and 1HNMR spectroscopy and magnetic moment measurements as well as thermal analysis (TGA and DTA). The elemental analysis information recommends that the stoichiometry of the complexes to be 1:2:1. The molar conductance measurements of the complexes indicate their non-electrolytic nature. The infrared spectral information showed the coordination sites of the free ligand with the central metal particle. The electronic absorption spectral information disclosed the existence of an octahedral geometry for Pt(II) and Pd(II) complexes. DOI: http://dx.doi.org/10.17807/orbital.v7i4.633

This article aimed to synthesis, spectroscopic, physicochemical characterizations, and catalytic studies on some ofloxacin (OFL) complexes with ruthenium(III) [Ru(III)] metal ions. The Ru(III)-OFL complex, [Ru(OFL)2(Cl)2]Cl and two mixed-ligand complexes, [Ru(OFL)(AA)(H2O)2]Cl2 derived from OFL as the primary ligand and amino acids [AA; either glycine (Gly) or alanine (Ala)] as the secondary ligands, were synthesized and characterized using microanalytical, spectroscopic, and physical techniques including element composition, molar conductivity, infrared, electronic spectra, thermal, X-ray powder diffraction (XRD), Energy dispersive X-ray spectroscopy (EDX), Scanning electron microscopy (SEM), and Transmittance electron microscopy (TEM) analyses. The element analysis data describe the formation of 1:2 [Ru(III):OFL] and 1:1:1 [Ru(III):OFL:AA] complexes. The octahedral geometry of the complexes was confirmed by their magnetic moment and diffused reflectance. Fourier Transform Infrared spectroscopic (FTIR) measurements suggested that the ligands chelated with Ru(III) ions through the nitrogen atoms of the piperazine ring. In vitro antibacterial efficiency of the OFL compounds was evaluated by paper disc diffusion method. Significant antimicrobial activities were observed for some compounds of the series.

Graphical abstract Abstract The mixed-ligand binuclear complexes [Co 2 (BIBP)(2,6-PDC) 2 (H 2 O) 4 ] (1), [Ni 2 (BIBP)(2,6-PDC) 2 (H 2 O) 4 ] (2), and the coordination polymers 1D-{[Zn(BIBP)(2,6-PDC)]·4.5H 2 O} n (3), 2D-[Ni 2 (BIBP)(2,5-PDC) 2 (H 2 O) 4 ] n (4), and 3D-{[Ni 2 (BIBP) 3 (2,3-PDC) 2 ]·3.75H 2 O} n (5) were synthesized in good yields, characterized by IR, thermogravimetry and single X-ray diffraction method (BIBP = 4,4′-bis(1-imidazolyl)biphenyl, 2,6-PDC = 2,6-pyridinedicarboxylate, 2,3-PDC = 2,3-pyridinedicarboxylate, 2,5-PDC = 2,5-pyridinedicarboxylate). Compounds 1 and 2 are binuclear complexes, compound 3 is a 1D polymer, 4 has a 2D laminated structure, and 5 represent a 3D framework. A common motif in the structures, independent of their dimensionality is the bridging action of the neutral BIBP ligand between two metal ions and a metal chelating coordination of the dianionic PDC ligand through the pyridine nitrogen atom and the carboxylate group in 2-position. The comparative single crystal X-ray structure investigations reveal the fine-tuning influence of the carboxylic group positions in the pyridinedicarboxylate (PDC) ligands and the metal nature on the final structure topology and dimensionality. Compounds 1 and 2 are isostructural and represent Co(II) and Ni(II) isomorphs, where the metal ions coordinate two water molecules and the 2,6-PDC ligand in ONO chelate mode, while the bidentate BIBP ligand link the metal ions into a dinuclear complex. In 3 the 2,6-PDC ligand coordinates to the zinc atom in the same ONO chelate mode and two bridging BIBP ligands give a coordination number of five and extend the structure to a 1D polymer with an enantiopure triple-stranded helix motif in a case of spontaneous resolution in the chiral tetragonal space group P 4 3 22. In 4 the 2,5-PDC ligand realises its chelate-bridging function and together with the bridging BIBP ligand form 2D layers with the Ni(II) atoms with hcb (honeycomb or 6,3) topology. In 5 the chelate-bridging 2,3-PDC and BIBP ligands form (4,4)-layers which are interlinked by additional BIBP pillars to a 3D network with two-fold interpenetration of symmetry-related networks. [ABSTRACT FROM AUTHOR]

The studies about the structures and biological properties of the mixed ligand metal complexes (Mn+, M = Mn, Fe, Co, Ni, Cu, Zn, Ag, Au, Ru, Os, Ir, Pd, Rh, U, Eu, and Tb) of the 2- aminobenzothiazole and some organic compounds (β-picoline, γ-picoline isopicoline, acetylaceton, o-hydroxyacetophenone, 1,2-ethylenediamine, piperazine, N,N'-bis (4-antipyrylmethyl) piperazine, N,N'-tetra(4-antipyrylmethyl)-1,2- diaminoethane, phtalamide, malonimide, benzylacetone, tetramethylenesulphoxide, catechol, p-chlorophenoxyacetic acid, 7-oxobicyclo[2.2.1]-heptan-2,3-dicarboxylic acid, 2,2'-bipyridine, 1,10-phenanthroline, propionic acid, phenoxyacetic acid, 2-amino-3- allylbenzothiazole, saccharine, triphenylphosphine, trichloroacetic acid, adipic acid, 1,4-benzenedicarboxylic acid, succinic acid, formic acid, picric acid, amino acid, p-formylphenoxyacetik acid and 2,6-pyridinedicarboxylic acid) have been observed in the literature. In these compounds, 2-aminobenzothiazole connected to the metal from N or S or amine group of thiazole ring or take part in the structure as the complementary form. Some biological properties such as antimicrobial, anticancer, antifungal, anti-inflammatory, antitumor and inhibition of carbonic anhydrase of these complexes are well-known. [ABSTRACT FROM AUTHOR]

Two new complexes {[Zn(H2L)(Bpp)] . H2O}n (I) and {[Ag(H3L)(Bpp)] . 0.25H2O}n (II) (H4L = 5-(2,3-dicarboxy phenoxy) isophthalic acid, Bpp = 1,3-bis(4-pyridyl)propane) were prepared and characterized by single crystal X-ray diffraction (XRD) (CCDC nos. 1578523 (I), 1578529 (II)), element analysis and powder XRD. Compound I showed a one-dimensional chain structure, in which the zinc(II) ion is fourcoordinated with a tetrahedral geometry. Compound II is a 1D chain structure with the H3L- suspension arms. Complexes I and II are further extended into three-dimensional supramolecular framework via hydrogen bonds and π-π interactions. The solid state luminescent properties of compounds I and II have been investigated. [ABSTRACT FROM AUTHOR]