Search

Your search keyword '"Kamoi K"' showing total 542 results
Start Over Author "Kamoi K" Search Limiters Peer Reviewed
542 results on '"Kamoi K"'

1. Anti-TNF therapy in the management of ocular attacks in an elderly patient with long-standing Behçet's disease

Author

Karube H, Kamoi K, and Ohno-Matsui K

Subjects
Behçet’s disease, anti-tumor necrosis factor  antibody, infliximab, adalimumab, elderly patient, Medicine (General), R5-920
Abstract

Hisako Karube, Koju Kamoi, Kyoko Ohno-Matsui Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan Background: Ocular symptoms in Behçet’s disease (BD) begin mostly before 30 years of age according to international surveys, and BD activity may decrease with age. Information regarding the treatment of ocular symptoms in elderly BD patients is thus scant. Anti-TNFα antibody has recently demonstrated strong effects against recurrent uveitis in BD, but the efficacy and safety of anti-TNFα therapy in elderly patients remain unclear. We report herein the case of an elderly patient with long-standing uveitis due to BD who was successfully treated with two types of anti-TNF therapy. Case: An 81-year-old Japanese man presented with a 33-year history of ocular inflammation due to BD. As immunosuppressive agents, such as cyclosporine A, were difficult to use because he had undergone removal of the left kidney due to cancer, he was treated with colchicine. However, attacks of ocular inflammation persisted around nine times a year. After colchicine had been changed to infliximab, ocular inflammation was fairly well controlled, but ocular attacks still occurred once or twice a year. As soon as intestinal hemorrhage related to BD occurred, infliximab was switched to adalimumab. After this switch, ocular attacks resolved and visual acuity was maintained at 1.0. Intestinal lesions were also well controlled, and no side effects were seen. Conclusion: This represents the first report of the application of two types of anti-TNFα therapy for ocular attacks in an elderly BD patient. In addition to infliximab, adalimumab appears to offer an alternative therapy for refractory, long-standing BD-related uveitis in elderly patients. Keywords: Behçet’s disease, anti-tumor necrosis factor-α antibody, infliximab, adalimumab, elderly patient

Published
2016

3. Fourteen-Membered Macrocyclic Fe Complexes for Oxygen Reduction Catalysis Inspired by FeN4 Centers Hosted by Graphene

Author

Takahama R, Okada M, Kamoi K, Ohyama J, Kojima R, Moriya M, Yuta Nabae, Kawashima S, and Hayakawa T

Subjects
Bond length, chemistry.chemical_compound, chemistry, Graphene, law, Chemical structure, Polymer chemistry, Polymer electrolyte fuel cells, Porphyrin, Pyrolysis, Oxygen reduction, law.invention, Catalysis
Abstract

For the globalization of polymer electrolyte fuel cells, the development of non-precious-metal (NPM) catalysts for oxygen reduction is extremely important. To date, many NPM catalysts have been synthesized by pyrolyzing Fe-, N-, and C-containing precursors, but they suffer from the density and uncertain chemical structure of their active sites. This study reports a 14-membered macrocyclic Fe complex, which was inspired by FeN4 centers in the pyrolyzed catalysts, whereas typical macrocyclic MN4 complexes have 16-membered rings. This 14-membered macrocycle has strong Fe-N bonding with an average bond distance of 1.90 Å, which has been evidenced by single-crystal X-ray diffraction, and is markedly shorter than that in porphyrin, 2.0 Å. Promising electrocatalytic activities for oxygen reduction have been demonstrated in both of acidic and basic media.

Published
2020

4. Abstracts of Poster Presentations

Author

Iguchi, Megumi, Ishiwata, Isamu, Tamagawa, Tomoharu, Ishiwata, Chieko, Kiguchi, Kazushige, Sato, Kahei, Saito, Shigeo, Yamamoto, Motoyoshi, Hashimoto, Hisashi, Tachibana, Toshiaki, Ohi, Satoshi, Akahori, Masakazu, Yokose, Takashi, Ishikawa, Hiroshi, Ohi S., Sato K., Kimura M., Kobayashi M., Hosaka K., Ishiwata, Ciko, Kiguci, Kazushige, Etsuko, Hasegawa, Tomoharu, Tamagawa, Yuko, Tokieda, Isamu, Ishiwata, Kahei, Sato, Sunaga, Junko, Tomimai, Ryoko, Motohashi, Hideyuki H., Nagaike, Koki, Tanaka, Hiroyuki, Itoh, Hiroshi, Fukushima, Tsuyoshi, Kohama, Kazuyo, Uchiyama, Shuichiro, Kataoka, Hiroaki, Yamamoto M., Yoshimoto T., Sekiya H., Negishi Y., Sakoda K., Izumi Y., Takao S., Ishikawa H., Tachibana T., Hashimoto H., Motoyama S., Sato E., Kamoi K., Iino M., Okayasu K., Osawa G., Nakaya H., Enomoto, Keiko, Kamoi, Hisahiro, Sato, Soh, Kamoi, Kyuichi, Wachi, Tomoka, Yoshida, Noriyuki, Yano, Yoshihisa, Ueno, Munehisa, Deguchi, Nobuhiro, Hirotsune, Shinji, Sasaki, Hiroyuki, Tsukita, Shoichiro, Tabei I., Ito R., Kyouda S., Ohkubo T., Ishida Y., Ishiwata I., Satou K., Kubo H., Yamazaki Y., Yanaga K., Sato, Yorino, Kazami, Ai, Okamoto, Naoki, Hosaka, Koji, Soma, Masayuki, Sato, Yoshiro, Sonobe, Makoto, Niimi S., Yamada K., Yasuda M., Tanaka T., Yamada, Kyosuke, Iida, Yasushi, Ueda, Kazu, Misawa, Akihiko, Suzuki, Nagazumi, Takahashi, Hiroyuki, Kato, Hiroyuki, Kimura, Eizo, Yasuda, Makoto, Tanaka, Tadao, Hiroshi, Mizuhara, Yohichi, Kobayashi, Yosuke, Kanishi, Soujiro, Sato, Haruhiro, Kondo, Yoshiki, Ohkuma, Tazuru, Ohhara, Yoshiko, Okuda, Mari, Watanabe, Asami, Okamura, Tomohiro, Iida, Kazushige, Kiguchi, Bunpei, Ishizuka, Ishikawa, Mayumi, Kimura, Kazuhiro, Akishima, Yuri, Shimojo, Masako, Ueshiba, Hajime, Tsuboi, Kumiko, Nakata, Koichiro, Akasaka, Yoshikjo, Shibuya, Kazutoshi, Yoshino, Gen, Matsuo, Yoshinobu, Drexler, Hans G., Harashima, Akira, Okochi, Ayumi, Orita, Kunzo, Kashiwagi H., Shigeya, Kyouda, Isao, Tabei, Satoshi, Ohi, Toshiaki, Tachibana, Hirotaka, Kubo, Hisashi, Hashimoto, Katsuhiko, Yanaga, Yoji, Yamazaki, Hiroshi, Ishikawa, Kudoh K., Takano M., Okamoto S., Sasaki K., Fujii K., Hirata J., Kita T., Kikuchi Y., Yoshioka, Kunihiko, Ohno, Yoshio, Gondo, Tatsuo, Nakagami, Yoshihiro, Matsushita, Kazuhito, Sakamoto, Noboru, Matumoto, Mayuko, Koga, Shouji, Namiki, Kazunori, Aoyagi, Teiichirou, Ohori, Makoto, Hatano, Tadashi, Tachibana, Masaaki, Kawamura, Takeshi, Nishimura, Toshihide, Mori, Y., Okumura, T., Shimada, Y., Okabe, Michio, Kaganoi, Junichi, Nagatani, Shiro, Kondo, Masato, Shimada, Yutaka, Watanabe, Go, Imamura, Masayuki, Kitahara, Shinzo, Tagawa, Yutaka, Ita, Masamichi, Smolewski, Piotr, Halicka, Dorota, and Darzynkiewicz, Zbigniew

Published
2004
Full Text
View/download PDF

11. 210 Randomized study of intravesical chemotherapy using pirarubicin in low- and intermediate risk non-muscle-invasive bladder cancer in Japan - comparison one immediate postoperative intravesical chemotherapy with short-term adjuvant intravesical chemotherapy after TURBT

Author

Naya, Y., primary, Shiraishi, T., additional, Oishi, M., additional, Ueda, T., additional, Nakanishi, H., additional, Nakamura, T., additional, Hongo, F., additional, Iwata, T., additional, Kanazawa, M., additional, Mikami, K., additional, Kamoi, K., additional, Okihara, K., additional, and Ukimura, O., additional

Published
2016
Full Text
View/download PDF

20. Lack of association between an ecNOS gene polymorphism and diabetic nephropathy in type 2 diabetic patients with proliferative diabetic retinopathy

Author

Osamu Hanyu, Takuma Narita, Katsunori Suzuki, Seiki Ito, Kamoi K, Ishii T, Hiroki Fujita, and Hiroyuki Meguro

Subjects
Male, medicine.medical_specialty, Genotype, Nitric Oxide Synthase Type III, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Biochemistry, Diabetic nephropathy, Endocrinology, Internal medicine, medicine, Humans, Diabetic Nephropathies, Allele, Allele frequency, Alleles, Aged, Diabetic Retinopathy, Polymorphism, Genetic, business.industry, Biochemistry (medical), General Medicine, Diabetic retinopathy, Middle Aged, medicine.disease, Endothelial Constitutive Nitric Oxide Synthase, Diabetes Mellitus, Type 2, Female, Gene polymorphism, Repeat polymorphism, Nitric Oxide Synthase, business
Abstract

The development of diabetic nephropathy shows remarkable variation among individuals. Therefore, not only hyperglycemia but also genetic factors may contribute to the development of diabetic nephropathy. The aim of the present study was to examine the contribution of the 27-bp repeat polymorphism in intron 4 of the endothelial constitutive nitric oxide synthase gene (ecNOS4) to the development of diabetic nephropathy. For this purpose, we analyzed this polymorphism in 167 Japanese type 2 diabetic patients with proliferative diabetic retinopathy consisting of 102 patients with diabetic nephropathy (with macroalbuminuria) and 65 patients without diabetic nephropathy (with normoalbuminuria). The genotype and allele frequencies were not significantly different between patients with diabetic nephropathy and those without diabetic nephropathy (ecNOS4 "b/b" 79.4% vs. 84.6%, ecNOS4 "b/a" 20.6% vs. 15.4%, "b" allele 89.7% vs. 92.3%, "a" allele 10.3% vs. 7.7%). We conclude that the ecNOS4 polymorphism does not contribute to the development of diabetic nephropathy.

Published
2000

Catalog

Books, media, physical & digital resources
See catalog results