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In order to explore the wind load characteristics acting on solar photovoltaic panels under extreme severe weather conditions, based on the Shear Stress Transport (SST) κ-ω turbulence model, numerical calculations of three-dimensional incompressible viscous steady flow were performed for four installation angles and two extreme wind directions of the solar photovoltaic panels. The wind load characteristics on both sides of the photovoltaic panels were obtained, and the vortex structure characteristics were analyzed using the Q criterion. The results indicate that, under different installation angles, the windward side pressure of the solar photovoltaic panel is generally higher than the leeward side. The leeward side is prone to forming larger vortices, increasing the fatigue and damage risk of the material, which significantly impacts the solar photovoltaic panel. As the installation angle increases, the windward side pressure of the solar photovoltaic panel also gradually increases. Therefore, optimal installation methods include installing the panel facing the wind at angles of 30° and 45°, or installing it facing away from the wind at a 60° angle, to minimize the impact of wind load on the solar photovoltaic panel. [ABSTRACT FROM AUTHOR]

[Display omitted] • Four new compounds were isolated from the fruits of Nicandra physaloides. • Seventeen known compounds were isolated from the genus Physalis for the first time. • Four compounds were showed strong anti-inflammatory activities. Twenty-one compounds were isolated and identified from the ethanol extract of the fruits of Nicandra physaloides , including four new (1 – 4) and 17 known compounds (5 – 21). All the compounds were isolated from the genus Physalis for the first time. In this study, NMR spectroscopy was used to study the compound structures by comparing their data with those reported in the literature. Moreover, the potential anti-inflammatory activity of RAW264.7 cells induced by lipopolysaccharide (LPS) was evaluated. Among the monoterpenoids, compounds (5–7 , 9) exhibited weak anti-inflammatory activities, with IC 50 values ranging from 29.10 to 68.30 μM. [ABSTRACT FROM AUTHOR]

Two new steroids meteloside F (1) and meteloside G (2), together with six known ones (3–8), were isolated and identified from the seeds of Datura metel L. The chemical constituents were isolated by silica gel, ODS chromatogram columns. and preparative HPLC. The structures of these compounds were established by one- and two-dimensional NMR spectra and HR-ESI-MS. The compounds exhibited inhibition on the nitric oxide release of lipopolysaccharide-induced RAW 264.7 cells with IC50 values from 30.2 to 44.8 μM. [ABSTRACT FROM AUTHOR]

This study was conducted to evaluate the feasibility, safety, biocompatibility, and degradation features of a fully biodegradable occluder for closure of atrial septal defect (ASD) in an acute canine model. The ASD was created in 20 healthy mongrel dogs by the brockenbrough needle, and the fully biodegradable occluders were implanted by self-made delivery system. The success rate and complications were observed. Acute ASD models were successfully created in 18 dogs, and 16 occluders were successfully implanted in the ASD models. Animals were sacrificed at different times after procedure. The cardiac gross anatomy showed that all occluders were stable in the interatrial septum, no vegetation or thrombus formation was observed on the surface of all occluders. They were embedded into endogenous host tissue gradually at 12-week follow-up. Different periods of pathological observations suggested that the occluders degraded gradually over about 24 weeks and essentially became an integral part of the septum. Transcatheter closure of ASD in acute canine model using the fully biodegradable ASD occluder has the potential of a high successful rate of technique, excellent biocompatibility, and fewer complications with adequate, immediate, and short-term results., 1. Introduction Atrial septal defect (ASD) is one of the most common congenital heart defect and accounts for about 30% of the congenital heart disease. With the development of interventions [...]

Twenty-one phenylpropanoids, including 1 new (1) and 20 known phenylpropanoids (2–21), were isolated and identified from the fruits of Nicandra physaloides. The structures of these compounds were established by 1D and 2D NMR spectra referring to the literatures, together with mass spectrometry. It was found that the isolated compounds, except for 7, 18 and 19, showed the different levels of inhibitions on NO production by LPS-induced RAW 264.7 cells at IC50 values from 27.0 to 97.3 μM. [ABSTRACT FROM AUTHOR]

Four new indole alkaloids, daturametelindoles A-D (1–4) were isolated from the EtOAc soluble partition of the ethanol extract of the Datura metel seeds. The structures of the new compounds were determined based on spectroscopic evidence, including their 1D- and 2D-NMR spectra and mass spectrometry. In particular, compounds 1–4 were all racemes, confirmed by the optical rotations and CD spectra. Unfortunately, the chiral monomers were not obtained due to the amount, but the developments of their chiral separation and chiral resolution were completed. All isolated compounds were evaluated for cytotoxic effects against human gastric adenocarcinoma cells (SGC-7901), human hepatoma (Hepg2), and human breast cancer (MCF-7). Unlabelled Image [ABSTRACT FROM AUTHOR]