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OBJECTIVES Human papillomavirus infection has been investigated intensively regarding oropharyngeal carcinoma. However, there is still lack of knowledge about the impact of oral HPV infections concerning oral squamous cell carcinoma. This study investigates the prevalence of oral HPV infection in such patients, identifying possible differences between HPV+ and HPV- patients. SUBJECTS AND METHODS One hundred and six consequent patients were investigated. After completion of a study questionnaire regarding risk factors, a brush smear sample was taken in each subject to identify the individual oral HPV status (overall/low risk/high risk). RESULTS About 35.8% of the patients were tested positive for HPV in the oral cavity (14% low risk, 28.3% high risk). Patients with oral HPV infection and high-risk HPV infection were significantly younger (p

Die zahnarztliche Behandlung schwangerer Patientinnen weist einige wichtige Besonderheiten auf, u. a. aufgrund der zahlreichen physiologischen Veranderungen, die eine Frau wahrend dieser intensiven Phase erlebt. Unsicherheit oder fehlendes Wissen vonseiten der behandelnden Zahnarzte bezuglich diagnostischer und therapeutischer Moglichkeiten in der Behandlung Schwangerer, speziell im Hinblick auf pharmakologische Fragen, fuhren haufig zu Fehlbehandlungen oder unzureichende Therapien. Deren Folgen reichen von unnotigen Schmerzepisoden und damit stressbedingten Belastungen der Mutter und des Ungeborenen bis hin zu ausgedehnten Abszedierungen im Kiefer- und Halsbereich aufgrund unzureichend behandelter dentogener Infektionen. Der vorliegende Artikel fasst die diagnostischen und therapeutischen Optionen sowie die Kontraindikationen fur zahnarztliche Behandlungen wahrend der Schwangerschaft zusammen. Mit den verfugbaren Optionen sind eine korrekte Diagnose und anschliesende Behandlung gefahrlos in Hinblick auf die Gesundheit der Mutter und des Fetus moglich.

Objective The role of human papilloma virus (HPV) infections in oral carcinogenesis is an important topic of research in maxillofacial oncology. Nevertheless, the association between such infections in the oral cavity and the development of oral precancerous lesions remains unclear. The aim of this study was to evaluate the association between oral HPV infections and oral leukoplakia or erythroplakia. Study Design The case control study included 118 patients with manifest oral leukoplakia or erythroplakia, who underwent surgical biopsy, including a histopathologic grading of the lesion, and 100 control patients without any oral lesions. HPV detection was achieved with a noninvasive brush smear method (Digene Cervical Sampler, Hybrid Capture II-Test). Logistic regression analysis was performed to assess the associations. Results A significant association was found between high-risk oral HPV infection and the presence of oral premalignant lesions (P = .001). Among all other evaluated parameters, only smoking showed a significant association with the presence of oral lesions. Conclusions Oral HPV infections may play a role in the pathogenesis of premalignant oral lesions.

The treatment of frontal sinus fractures is still a matter of research in neurosurgical and craniofacial surgery. The present study aimed to determine new criteria regarding surgical or observational treatment, especially concerning the fracture dislocation. Clinical information on 164 consecutive patients with fractures of the frontal sinus, treated at the Department of Craniomaxillofacial Surgery of the Medical University of Innsbruck from 2006 to 2010, have been evaluated. 23 female (14%) and 141 male (86%) patients suffered mainly from traffic (31.7%) and sports accidents (28.0%), followed by work accidents (20.1%), violence (3.7%) and accidents at home (3.1%). 51.8% presented an isolated fracture of the anterior wall, 47.6% both anterior and posterior wall fracture, 0.6% an isolated posterior wall fracture. Injury of the nasofrontal duct was found in 29.2%, CSF liquorrhoea in 15.9%. In total, 44.5% of the patients underwent surgical therapy, 55.5% were treated conservatively by observation. Treatment decision depended significantly on concomitant injuries of the nasofrontal duct and the presence of rhinoliquorrhoea as well as on the fracture dislocation. A new classification of frontal sinus fractures depending on their maximum dislocation is proposed. In addition, a treatment algorithm considering displacement, liquorrhoea and injury of the nasofrontal duct is presented.

Odontogenic infections represented a challenge for every craniomaxillofacial surgeon in the pre-antibiotic era, not least due to the frequent association with septic complications and lethal consequences. Nowadays, the incidences of serious infection-related complications are less frequent thanks to the medical progress. Nevertheless, the development of severe infections is still hard to foresee. The following analysis provides an overview of four patients with severe, life-threatening odontogenic deep neck space infections treated at the University Clinic for Oral and Maxillofacial Surgery in Innsbruck and describes the etiology, therapy, and outcome for each patient while analyzing differences between the single cases. Crucial aspects in origin, progression, and treatment of DNIs are highlighted, comparing the results with the international literature.

Die Anwendung von Bisphosphonaten ist mittlerweile grundlegend in der Therapie mehrerer ossarer Erkrankungen wie dem multiplen Myelom und Knochenmetastasen sowie in der Osteoporosebehandlung. Die Verabreichung erfolgt dabei in oraler wie auch parenteraler Form. Durch den weitverbreiteten Gebrauch steigt auch die Fallzahl der assoziierten Komplikationen. Die Bisphosphonat-asso-ziierte Knochennekrose des Kiefers stellt eine solche Komplikation dar. Die zahnarztliche und kieferchirurgische Tatigkeit spielt deshalb in der Prophylaxe und Therapie solcher Knochennekrosen eine zentrale Rolle. Anhand eines Fall-beispiels wird der langwierige Krankheitsverlauf einer mit Bisphosphonaten therapierten Patientin beschrieben, von Beginn der Erkrankung durch eine apikale Parodontitis bis zur endgultigen chirurgischen Therapie durch UK-Teil-resektion. Der Fall wird mit Daten der verfugbaren Literatur verglichen um mogliche Verbesserungen in der Prophylaxe und Therapie der BRONJ aufzudecken.