2,517 results
Search Results
2. Automated Segmentation of the Right Ventricle from Magnetic Resonance Imaging Using Deep Convolutional Neural Networks
- Author
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Punithakumar, Kumaradevan, Carscadden, Adam, Noga, Michelle, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Puyol Antón, Esther, editor, Pop, Mihaela, editor, Martín-Isla, Carlos, editor, Sermesant, Maxime, editor, Suinesiaputra, Avan, editor, Camara, Oscar, editor, Lekadir, Karim, editor, and Young, Alistair, editor
- Published
- 2022
- Full Text
- View/download PDF
3. Right Ventricular Segmentation in Multi-view Cardiac MRI Using a Unified U-net Model
- Author
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Queirós, Sandro, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Puyol Antón, Esther, editor, Pop, Mihaela, editor, Martín-Isla, Carlos, editor, Sermesant, Maxime, editor, Suinesiaputra, Avan, editor, Camara, Oscar, editor, Lekadir, Karim, editor, and Young, Alistair, editor
- Published
- 2022
- Full Text
- View/download PDF
4. A Deep Convolutional Neural Network Approach for the Segmentation of Cardiac Structures from MRI Sequences
- Author
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Carscadden, Adam, Noga, Michelle, Punithakumar, Kumaradevan, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Puyol Anton, Esther, editor, Pop, Mihaela, editor, Sermesant, Maxime, editor, Campello, Victor, editor, Lalande, Alain, editor, Lekadir, Karim, editor, Suinesiaputra, Avan, editor, Camara, Oscar, editor, and Young, Alistair, editor
- Published
- 2021
- Full Text
- View/download PDF
5. Style Data Augmentation for Robust Segmentation of Multi-modality Cardiac MRI
- Author
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Ly, Buntheng, Cochet, Hubert, Sermesant, Maxime, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Pop, Mihaela, editor, Sermesant, Maxime, editor, Camara, Oscar, editor, Zhuang, Xiahai, editor, Li, Shuo, editor, Young, Alistair, editor, Mansi, Tommaso, editor, and Suinesiaputra, Avan, editor
- Published
- 2020
- Full Text
- View/download PDF
6. Electroanatomic mapping in athletes: Why and when. An expert opinion paper from the Italian Society of Sports Cardiology.
- Author
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Dello Russo, Antonio, Compagnucci, Paolo, Zorzi, Alessandro, Cavarretta, Elena, Castelletti, Silvia, Contursi, Maurizio, D'Aleo, Antonio, D'Ascenzi, Flavio, Mos, Lucio, Palmieri, Vincenzo, Patrizi, Giampiero, Pelliccia, Antonio, Sarto, Patrizio, Delise, Pietro, Zeppilli, Paolo, Romano, Silvio, Palamà, Zefferino, and Sciarra, Luigi
- Subjects
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CARDIAC magnetic resonance imaging , *VENTRICULAR arrhythmia , *SPORTS medicine , *CARDIAC arrest , *SPORTS physicians - Abstract
Three-dimensional electroanatomical mapping (EAM) has the potential to identify the pathological substrate underlying ventricular arrhythmias (VAs) in different clinical settings by detecting myocardial areas with abnormally low voltages, which reflect the presence of different cardiomyopathic substrates. In athletes, the added value of EAM may be to enhance the efficacy of third-level diagnostic tests and cardiac magnetic resonance (CMR) in detecting concealed arrhythmogenic cardiomyopathies. Additional benefits of EAM in the athlete include the potential impact on disease risk stratification and the consequent implications for eligibility to competitive sports. This opinion paper of the Italian Society of Sports Cardiology aims to guide general sports medicine physicians and cardiologists on the clinical decision when to eventually perform an EAM study in the athlete, highlighting strengths and weaknesses for each cardiovascular disease at risk of sudden cardiac death during sport. The importance of early (preclinical) diagnosis to prevent the negative effects of exercise on phenotypic expression, disease progression, and worsening of the arrhythmogenic substrate is also addressed. • Three-dimensional electroanatomical mapping (EAM) has the potential to identify the pathological substrate underlying ventricular arrhythmias (VAs). • In athletes, EAM may enhance the efficacy of third-level diagnostic tests and cardiac magnetic resonance (CMR) in detecting concealed arrhythmogenic cardiomyopathies. • An electroanatomical mapping-guided endomyocardial biopsy may be considered as additional diagnostic tool among athletes presenting with complex ventricular arrhythmias and unclear findings after comprehensive clinical-imaging assessments and genetic testing. • The role of electroanatomical mapping is particularly relevant in the differentiation between myocarditis and forms of arrhythmogenic cardiomyopathy, especially if integrated with the biopsy and histological examination that allows sampling in an extremely precise way the areas of altered voltage, expression of myocardial fibrosis. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
7. Multi-Planar Deep Segmentation Networks for Cardiac Substructures from MRI and CT
- Author
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Mortazi, Aliasghar, Burt, Jeremy, Bagci, Ulas, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Pop, Mihaela, editor, Sermesant, Maxime, editor, Jodoin, Pierre-Marc, editor, Lalande, Alain, editor, Zhuang, Xiahai, editor, Yang, Guang, editor, Young, Alistair, editor, and Bernard, Olivier, editor
- Published
- 2018
- Full Text
- View/download PDF
8. Automatic Cardiac Disease Assessment on cine-MRI via Time-Series Segmentation and Domain Specific Features
- Author
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Isensee, Fabian, Jaeger, Paul F., Full, Peter M., Wolf, Ivo, Engelhardt, Sandy, Maier-Hein, Klaus H., Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Pop, Mihaela, editor, Sermesant, Maxime, editor, Jodoin, Pierre-Marc, editor, Lalande, Alain, editor, Zhuang, Xiahai, editor, Yang, Guang, editor, Young, Alistair, editor, and Bernard, Olivier, editor
- Published
- 2018
- Full Text
- View/download PDF
9. European Neuroendocrine Tumor Society (ENETS) 2022 Guidance Paper for Carcinoid Syndrome and Carcinoid Heart Disease.
- Author
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Grozinsky‐Glasberg, Simona, Davar, Joseph, Hofland, Johannes, Dobson, Rebecca, Prasad, Vikas, Pascher, Andreas, Denecke, Timm, Tesselaar, Margot E. T., Panzuto, Francesco, Albåge, Anders, Connolly, Heidi M., Obadia, Jean‐Francois, Riechelmann, Rachel, and Toumpanakis, Christos
- Subjects
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EXOCRINE pancreatic insufficiency , *MAST cell disease , *NEUROENDOCRINE tumors , *HEART diseases , *CARCINOID , *BRAIN natriuretic factor , *CARDIAC magnetic resonance imaging - Abstract
Data regarding the diagnosis, management, and follow-up of carcinoid syndrome (CS) and carcinoid heart disease (CHD) were identified by searches of the MEDLINE database using specific terms in human studies: CS; CHD; screening; epidemiology; diagnosis; treatment; prognosis. CS, carcinoid syndrome; CHD, carcinoid heart disease; MDT, multidisciplinary team; PRRT, peptide receptor radioligand, therapy; SSA, somatostatin analogues; u5-HIAA, urinary 5-hydroxiindolic acid gl Ultimately, all patients develop symptomatic progression of CS when on an SSA. 2 TABLELevel of evidence and grade of recommendation as specified in the GRADE criteria HT
ht A. INTRODUCTION: GENERAL BACKGROUND a. Tumour burden is a relevant contributor to CS-associated mortality.4 CHD is present in approximately 20%-50% of CS patients and is a major prognostic indicator, with reduced overall survival at 3 years of 31% in patients with CHD, compared to 69% in patients without CHD.8 d. [Extracted from the article]Level of evidence for studies of diagnostic tests Criteria 1 An independent, masked comparison with reference standard among an appropriate population of consecutive patients 2 An independent, masked comparison with reference standard among non-consecutive patients or confined to a narrow population of study patients 3 An independent, masked comparison with an appropriate population of patients, but reference standard not applied to all study patients 4 Reference standard not applied independently or masked 5 Expert opinion with no explicit critical appraisal, based on physiology, bench research, or first principles - Published
- 2022
- Full Text
- View/download PDF
10. Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper
- Author
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Lancellotti, P., Pibarot, P., Chambers, J., Canna, G. la, Pepi, M., Dulgheru, R., Dweck, M., Delgado, V., Garbi, M., Vannan, M.A., Montaigne, D., Badano, L., Maurovich-Horvat, P., Pontone, G., Vahanian, A., Donal, E., Cosyns, B., European Assoc Cardiovasc Imaging, Centre Hospitalier Universitaire de Liège (CHU-Liège), Maria Cecilia Hospital [Cotignola], Anthea Hospital [Bari, Italy], Université Laval [Québec] (ULaval), Guy's and St Thomas' Hospital [London], Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), University of Edinburgh, Universiteit Leiden, University of Cambridge [UK] (CAM), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Semmelweis University of Medicine [Budapest], Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Universitair Ziekenhuis Brussel = University Hospital of Brussels (UZ Brussel), Universiteit Leiden [Leiden], Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Université Sorbonne Paris Nord, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Universitair Ziekenhus Brussel (UZ Brussel), Clinical sciences, Cardio-vascular diseases, Cardiology, Lancellotti, P, Pibarot, P, Chambers, J, La Canna, G, Pepi, M, Dulgheru, R, Dweck, M, Delgado, V, Garbi, M, Vannan, M, Montaigne, D, Badano, L, Maurovich-Horvat, P, Pontone, G, Vahanian, A, Donal, E, and Cosyns, B
- Subjects
mitral valve ,cardiac magnetic resonance imaging ,Heart Valve Diseases ,Mitral Valve Insufficiency ,computed tomography ,General Medicine ,MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE ,tricuspid valve ,aortic valve ,Multimodal Imaging ,Tricuspid Valve Insufficiency ,valvular regurgitation ,pulmonary valve ,expert's consensu ,Echocardiography ,cardiovascular system ,Humans ,Radiology, Nuclear Medicine and imaging ,[SDV.IB]Life Sciences [q-bio]/Bioengineering ,expert's consensus ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine - Abstract
Valvular regurgitation represents an important cause of cardiovascular morbidity and mortality. Imaging is pivotal in the evaluation of native valve regurgitation and echocardiography is the primary imaging modality for this purpose. The imaging assessment of valvular regurgitation should integrate quantification of the regurgitation, assessment of the valve anatomy and function, and the consequences of valvular disease on cardiac chambers. In clinical practice, the management of patients with valvular regurgitation largely relies on the results of imaging. It is crucial to provide standards that aim at establishing a baseline list of measurements to be performed when assessing native valve regurgitation. The present document aims to present clinical guidance for the multi-modality imaging assessment of native valvular regurgitation.
- Published
- 2021
11. Case report of isolated cardiac sarcoidosis presenting as hypertrophic obstructive cardiomyopathy—a clinical picture printed on lenticular paper
- Author
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Isadora Sande Mathias, Jorge Otávio Oliveira Lima Filho, E. Rene Rodriguez, Daniel A. Culver, Christine Jellis, Manuel L. Ribeiro Neto, and Carmela D. Tan
- Subjects
medicine.medical_specialty ,Cardiomyopathy ,030204 cardiovascular system & hematology ,Asymptomatic ,03 medical and health sciences ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Isolated cardiac sarcoidosis ,Internal medicine ,Case report ,Hypertrophic obstructive cardiomyopathy ,Fluorodeoxyglucose positron emission tomography ,medicine ,Ventricular outflow tract ,AcademicSubjects/MED00200 ,cardiovascular diseases ,030212 general & internal medicine ,medicine.diagnostic_test ,business.industry ,Hypertrophic cardiomyopathy ,Septal myectomy ,medicine.disease ,Stenosis ,cardiovascular system ,Cardiology ,Sarcoidosis ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Abstract
BackgroundCardiac sarcoidosis (CS) is an inflammatory granulomatous process of the myocardium that can be asymptomatic or have several different clinical phenotypes. One of its rarely described presentations consists of hypertrophy of the septal myocardium, similar to hypertrophic cardiomyopathy (HCM). Isolated cardiac sarcoidosis that haemodynamically mimics hypertrophic obstructive cardiomyopathy (HOCM) has been rarely described in the literature.Case summaryA 64-year-old Caucasian female previously diagnosed with non-critical aortic stenosis presented with pre-syncope, and echocardiography showed significant obstruction based on left ventricular outflow tract gradients, confirmed by cardiac magnetic resonance (CMR), concerning for a phenocopy of HCM. Septal myectomy was performed and pathology specimen revealed non-caseating granulomata consistent with cardiac sarcoidosis. She was started on oral corticosteroids and initial cardiac fluorodeoxyglucose positron emission tomography (FDG-PET) done after 1 month of treatment was negative. Repeat FDG-PET 15 months later, in the setting of haemodynamic decompensation, demonstrated diffuse FDG uptake in the myocardium without extra-cardiac involvement.DiscussionOur case brings together two entities: isolated cardiac sarcoidosis and its presentation mimicking HOCM, which has been very rarely described in the literature. And it also shows the scenario of surgical pathology diagnosis of sarcoidosis that was not suspected by initial CMR or FDG-PET, despite adequate preparation, only appearing on repeat FDG-PET done 15 months later. Isolated cardiac sarcoidosis should remain a differential diagnosis for any non-ischaemic cardiomyopathy without a clear cause, despite imaging evidence of HCM.
- Published
- 2021
12. An open-label, non-inferiority randomized controlled trial of lidocAine Versus Opioids In MyocarDial Infarction study (AVOID-2 study) methods paper
- Author
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Diem Dinh, Karlheinz Peter, Paul S. Myles, Jeffrey Lefkovits, Dion Stub, Karen Smith, Himawan Fernando, Janet Bray, Emily Andrew, Michael Stephenson, Angela Brennan, Jocasta Ball, Catherine Milne, Danny Liew, Andrew J. Taylor, Ziad Nehme, and Stephen Bernard
- Subjects
Adult ,Acute coronary syndrome ,Lidocaine ,Myocardial Infarction ,law.invention ,Percutaneous Coronary Intervention ,Randomized controlled trial ,Cardiac magnetic resonance imaging ,law ,medicine ,Humans ,Pharmacology (medical) ,Myocardial infarction ,Acute Coronary Syndrome ,medicine.diagnostic_test ,business.industry ,General Medicine ,medicine.disease ,Analgesics, Opioid ,Treatment Outcome ,Anesthesia ,Morphine ,ST Elevation Myocardial Infarction ,Ischemic chest pain ,business ,Ticagrelor ,medicine.drug - Abstract
Background There is increasing evidence that opioids interfere with the oral bioavailability of P2Y12 inhibitors leading to delayed onset of antiplatelet effects. Several strategies have been proposed to mitigate this interaction including utilizing alternative analgesic agents in the management of ischemic chest pain. Methods The lidocAine Versus Opioids In MyocarDial Infarction (AVOID-2) study is a phase II, pre-hospital, open-label, non-inferiority, randomized controlled trial conducted by Ambulance Victoria and Monash University in metropolitan Melbourne, Victoria, Australia. The purpose of the study is to compare the analgesic effect (reduction in pain by arrival to hospital) and safety (e.g. adverse drug reactions) (co-primary endpoints) of intravenous lidocaine versus intravenous fentanyl in 300 adult patients attended by ambulance with suspected ST-elevation myocardial infarction (STEMI). Secondary endpoints and a cardiac magnetic resonance imaging (MRI) sub-study will also compare infarct size between these two groups. Conclusions The evaluation of alternative analgesic agents in the management of acute coronary syndromes is urgently needed to manage the opioid-P2Y12 inhibitor interaction. The results of this trial will have significant implications on the emergency management of acute coronary syndromes internationally.
- Published
- 2021
13. Heart Best Paper Award 2023.
- Author
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Otto, Catherine M.
- Subjects
CARDIAC magnetic resonance imaging ,AWARDS ,HEART - Published
- 2023
- Full Text
- View/download PDF
14. Clinical application of CMR in cardiomyopathies: evolving concepts and techniques: A position paper of myocardial and pericardial diseases and cardiac magnetic resonance working groups of Italian society of cardiology.
- Author
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Merlo, Marco, Gagno, Giulia, Baritussio, Anna, Bauce, Barbara, Biagini, Elena, Canepa, Marco, Cipriani, Alberto, Castelletti, Silvia, Dellegrottaglie, Santo, Guaricci, Andrea Igoren, Imazio, Massimo, Limongelli, Giuseppe, Musumeci, Maria Beatrice, Parisi, Vanda, Pica, Silvia, Pontone, Gianluca, Todiere, Giancarlo, Torlasco, Camilla, Basso, Cristina, and Sinagra, Gianfranco
- Subjects
CARDIAC magnetic resonance imaging ,PERICARDIUM diseases ,CARDIOMYOPATHIES ,CLINICAL medicine ,PROGNOSIS ,LEFT ventricular hypertrophy - Abstract
Cardiac magnetic resonance (CMR) has become an essential tool for the evaluation of patients affected or at risk of developing cardiomyopathies (CMPs). In fact, CMR not only provides precise data on cardiac volumes, wall thickness, mass and systolic function but it also a non-invasive characterization of myocardial tissue, thus helping the early diagnosis and the precise phenotyping of the different CMPs, which is essential for early and individualized treatment of patients. Furthermore, several CMR characteristics, such as the presence of extensive LGE or abnormal mapping values, are emerging as prognostic markers, therefore helping to define patients' risk. Lastly new experimental CMR techniques are under investigation and might contribute to widen our knowledge in the field of CMPs. In this perspective, CMR appears an essential tool to be systematically applied in the diagnostic and prognostic work-up of CMPs in clinical practice. This review provides a deep overview of clinical applicability of standard and emerging CMR techniques in the management of CMPs. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
15. Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper.
- Author
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Lancellotti, Patrizio, Pibarot, Philippe, Chambers, John, Canna, Giovanni La, Pepi, Mauro, Dulgheru, Raluca, Dweck, Mark, Delgado, Victoria, Garbi, Madalina, Vannan, Mani A, Montaigne, David, Badano, Luigi, Maurovich-Horvat, Pal, Pontone, Gianluca, Vahanian, Alec, Donal, Erwan, Cosyns, Bernard, and Imaging, the Scientific Document Committee of the European Association of Cardiovascular
- Subjects
HEART valve diseases ,ECHOCARDIOGRAPHY ,MITRAL valve insufficiency ,THREE-dimensional imaging ,TRICUSPID valve diseases ,MAGNETIC resonance imaging ,PULMONARY valve diseases ,HEART valves ,COMPUTED tomography ,AORTIC valve insufficiency - Abstract
Valvular regurgitation represents an important cause of cardiovascular morbidity and mortality. Imaging is pivotal in the evaluation of native valve regurgitation and echocardiography is the primary imaging modality for this purpose. The imaging assessment of valvular regurgitation should integrate quantification of the regurgitation, assessment of the valve anatomy and function, and the consequences of valvular disease on cardiac chambers. In clinical practice, the management of patients with valvular regurgitation largely relies on the results of imaging. It is crucial to provide standards that aim at establishing a baseline list of measurements to be performed when assessing native valve regurgitation. The present document aims to present clinical guidance for the multi-modality imaging assessment of native valvular regurgitation. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
16. European Association of Cardiovascular Imaging (EACVI) position paper: Multimodality imaging in pericardial disease
- Author
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Arsen D. Ristić, Sven Plein, Stephan Achenbach, Petros Nihoyanopoulos, Mauro Pepi, Maria João Andrade, Bernard P. Paelinck, Bernard Cosyns, Patrizio Lancellotti, Massimo Imazio, Otto A. Smiseth, Clinical sciences, and ESC WG Myocardial Pericardial Dis
- Subjects
Constrictive pericarditis ,Male ,medicine.medical_specialty ,Cardiac computed tomography ,Magnetic Resonance Imaging, Cine ,Context (language use) ,Pericardial effusion ,Multimodal Imaging ,Sensitivity and Specificity ,Pericardial Effusion ,Medizinische Fakultät ,Cardiac magnetic resonance imaging ,Cardiac tamponade ,medicine ,Medical imaging ,Pericardium ,Humans ,Radiology, Nuclear Medicine and imaging ,ddc:610 ,PERICARDIAL DISEASE ,Societies, Medical ,medicine.diagnostic_test ,business.industry ,Pericarditis, Constrictive ,Magnetic resonance imaging ,Pericardiocentesis ,General Medicine ,medicine.disease ,Cardiac Tamponade ,Europe ,medicine.anatomical_structure ,Echocardiography ,Practice Guidelines as Topic ,Female ,Human medicine ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Tomography, X-Ray Computed ,Echocardiography, Transesophageal - Abstract
Although pericardial diseases are common in the daily clinical practice and can result in a significant morbidity and mortality, imaging of patients with suspected or known pericardial disorders remain challenging. Multimodality imaging is part of the management of pericardial diseases. Echocardiography, cardiac computed tomography, and cardiovascular magnetic resonance are often used as complementary imaging modalities. The choice of one or multiple imaging modalities is driven by the clinical context or conditions of the patient. The scope of the present document is to highlight the respective role of each technique according to the clinical context in the diagnosis and management of pericardial diseases.
- Published
- 2014
17. European Heart Journal paper on COVID-19 scoops top award for London-based researcher.
- Author
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Ozkan, Judith
- Subjects
CARDIAC amyloidosis ,RESEARCH awards ,CARDIAC magnetic resonance imaging ,COVID-19 ,HEART - Published
- 2022
- Full Text
- View/download PDF
18. A cardiac MRI motion artifact reduction method based on edge enhancement network.
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Jiang, Nanhe, Zhang, Yucun, Li, Qun, Fu, Xianbin, and Fang, Dongqing
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CARDIAC magnetic resonance imaging ,GAUSSIAN curvature ,MAGNETIC resonance imaging ,MOTION ,FEATURE extraction - Abstract
Cardiac magnetic resonance imaging (MRI) usually requires a long acquisition time. The movement of the patients during MRI acquisition will produce image artifacts. Previous studies have shown that clear MR image texture edges are of great significance for pathological diagnosis. In this paper, a motion artifact reduction method for cardiac MRI based on edge enhancement network is proposed. Firstly, the four-plane normal vector adaptive fractional differential mask is applied to extract the edge features of blurred images. The four-plane normal vector method can reduce the noise information in the edge feature maps. The adaptive fractional order is selected according to the normal mean gradient and the local Gaussian curvature entropy of the images. Secondly, the extracted edge feature maps and blurred images are input into the de-artifact network. In this network, the edge fusion feature extraction network and the edge fusion transformer network are specially designed. The former combines the edge feature maps with the fuzzy feature maps to extract the edge feature information. The latter combines the edge attention network and the fuzzy attention network, which can focus on the blurred image edges. Finally, extensive experiments show that the proposed method can obtain higher peak signal-to-noise ratio and structural similarity index measure compared to state-of-art methods. The de-artifact images have clear texture edges. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
19. Case report of isolated cardiac sarcoidosis presenting as hypertrophic obstructive cardiomyopathy—a clinical picture printed on lenticular paper.
- Author
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Mathias, Isadora Sande, Filho, Jorge Otávio Oliveira Lima, Culver, Daniel A, Rodriguez, E Rene, Tan, Carmela D, Neto, Manuel L Ribeiro, and Jellis, Christine L
- Subjects
SARCOIDOSIS ,CARDIOMYOPATHIES ,MAGNETIC resonance - Abstract
Background Cardiac sarcoidosis (CS) is an inflammatory granulomatous process of the myocardium that can be asymptomatic or have several different clinical phenotypes. One of its rarely described presentations consists of hypertrophy of the septal myocardium, similar to hypertrophic cardiomyopathy (HCM). Isolated cardiac sarcoidosis that haemodynamically mimics hypertrophic obstructive cardiomyopathy (HOCM) has been rarely described in the literature. Case summary A 64-year-old Caucasian female previously diagnosed with non-critical aortic stenosis presented with pre-syncope, and echocardiography showed significant obstruction based on left ventricular outflow tract gradients, confirmed by cardiac magnetic resonance (CMR), concerning for a phenocopy of HCM. Septal myectomy was performed and pathology specimen revealed non-caseating granulomata consistent with cardiac sarcoidosis. She was started on oral corticosteroids and initial cardiac fluorodeoxyglucose positron emission tomography (FDG-PET) done after 1 month of treatment was negative. Repeat FDG-PET 15 months later, in the setting of haemodynamic decompensation, demonstrated diffuse FDG uptake in the myocardium without extra-cardiac involvement. Discussion Our case brings together two entities: isolated cardiac sarcoidosis and its presentation mimicking HOCM, which has been very rarely described in the literature. And it also shows the scenario of surgical pathology diagnosis of sarcoidosis that was not suspected by initial CMR or FDG-PET, despite adequate preparation, only appearing on repeat FDG-PET done 15 months later. Isolated cardiac sarcoidosis should remain a differential diagnosis for any non-ischaemic cardiomyopathy without a clear cause, despite imaging evidence of HCM. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
20. An open-label, non-inferiority randomized controlled trial of lidocAine Versus Opioids In MyocarDial Infarction study (AVOID-2 study) methods paper.
- Author
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Fernando, Himawan, Milne, Catherine, Nehme, Ziad, Ball, Jocasta, Bernard, Stephen, Stephenson, Michael, Myles, Paul S., Bray, Janet E., Lefkovits, Jeffrey, Liew, Danny, Peter, Karlheinz, Brennan, Angela, Dinh, Diem, Andrew, Emily, Taylor, Andrew J., Smith, Karen, and Stub, Dion
- Subjects
- *
LIDOCAINE , *DRUG side effects , *FENTANYL , *RANDOMIZED controlled trials , *ACUTE coronary syndrome , *CARDIAC magnetic resonance imaging - Abstract
Background There is increasing evidence that opioids interfere with the oral bioavailability of P2Y 12 inhibitors leading to delayed onset of antiplatelet effects. Several strategies have been proposed to mitigate this interaction including utilizing alternative analgesic agents in the management of ischemic chest pain. Methods The lidocAine Versus Opioids In MyocarDial Infarction (AVOID-2) study is a phase II, pre-hospital, open-label, non-inferiority, randomized controlled trial conducted by Ambulance Victoria and Monash University in metropolitan Melbourne, Victoria, Australia. The purpose of the study is to compare the analgesic effect (reduction in pain by arrival to hospital) and safety (e.g. adverse drug reactions) (co-primary endpoints) of intravenous lidocaine versus intravenous fentanyl in 300 adult patients attended by ambulance with suspected ST-elevation myocardial infarction (STEMI). Secondary endpoints and a cardiac magnetic resonance imaging (MRI) sub-study will also compare infarct size between these two groups. Conclusions The evaluation of alternative analgesic agents in the management of acute coronary syndromes is urgently needed to manage the opioid-P2Y 12 inhibitor interaction. The results of this trial will have significant implications on the emergency management of acute coronary syndromes internationally. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
21. Future Horizons: The Potential Role of Artificial Intelligence in Cardiology.
- Author
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Patrascanu, Octavian Stefan, Tutunaru, Dana, Musat, Carmina Liana, Dragostin, Oana Maria, Fulga, Ana, Nechita, Luiza, Ciubara, Alexandru Bogdan, Piraianu, Alin Ionut, Stamate, Elena, Poalelungi, Diana Gina, Dragostin, Ionut, Iancu, Doriana Cristea-Ene, Ciubara, Anamaria, and Fulga, Iuliu
- Subjects
ARTIFICIAL intelligence ,MACHINE learning ,CARDIAC magnetic resonance imaging ,ARRHYTHMIA ,CARDIOVASCULAR diseases ,CORONARY angiography ,LITERATURE reviews - Abstract
Cardiovascular diseases (CVDs) are the leading cause of premature death and disability globally, leading to significant increases in healthcare costs and economic strains. Artificial intelligence (AI) is emerging as a crucial technology in this context, promising to have a significant impact on the management of CVDs. A wide range of methods can be used to develop effective models for medical applications, encompassing everything from predicting and diagnosing diseases to determining the most suitable treatment for individual patients. This literature review synthesizes findings from multiple studies that apply AI technologies such as machine learning algorithms and neural networks to electrocardiograms, echocardiography, coronary angiography, computed tomography, and cardiac magnetic resonance imaging. A narrative review of 127 articles identified 31 papers that were directly relevant to the research, encompassing a broad spectrum of AI applications in cardiology. These applications included AI models for ECG, echocardiography, coronary angiography, computed tomography, and cardiac MRI aimed at diagnosing various cardiovascular diseases such as coronary artery disease, hypertrophic cardiomyopathy, arrhythmias, pulmonary embolism, and valvulopathies. The papers also explored new methods for cardiovascular risk assessment, automated measurements, and optimizing treatment strategies, demonstrating the benefits of AI technologies in cardiology. In conclusion, the integration of artificial intelligence (AI) in cardiology promises substantial advancements in diagnosing and treating cardiovascular diseases. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Seg-CapNet: A Capsule-Based Neural Network for the Segmentation of Left Ventricle from Cardiac Magnetic Resonance Imaging
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Jie Li, Nan Lin, Cong Yang, Chang Liu, Yangjie Cao, Shuang Wu, and Yuan Wang
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capsule neural network ,Computer science ,Feature vector ,cardiac magnetic resonance imaging ,02 engineering and technology ,Grayscale ,left ventricle segmentation ,Theoretical Computer Science ,Sørensen–Dice coefficient ,Regular Paper ,0202 electrical engineering, electronic engineering, information engineering ,Segmentation ,image segmentation ,Artificial neural network ,business.industry ,020207 software engineering ,Pattern recognition ,Image segmentation ,Computer Science Applications ,Computational Theory and Mathematics ,Hardware and Architecture ,Feature (computer vision) ,Artificial intelligence ,business ,Encoder ,Software - Abstract
Deep neural networks (DNNs) have been extensively studied in medical image segmentation. However, existing DNNs often need to train shape models for each object to be segmented, which may yield results that violate cardiac anatomical structure when segmenting cardiac magnetic resonance imaging (MRI). In this paper, we propose a capsule-based neural network, named Seg-CapNet, to model multiple regions simultaneously within a single training process. The Seg-CapNet model consists of the encoder and the decoder. The encoder transforms the input image into feature vectors that represent objects to be segmented by convolutional layers, capsule layers, and fully-connected layers. And the decoder transforms the feature vectors into segmentation masks by up-sampling. Feature maps of each down-sampling layer in the encoder are connected to the corresponding up-sampling layers, which are conducive to the backpropagation of the model. The output vectors of Seg-CapNet contain low-level image features such as grayscale and texture, as well as semantic features including the position and size of the objects, which is beneficial for improving the segmentation accuracy. The proposed model is validated on the open dataset of the Automated Cardiac Diagnosis Challenge 2017 (ACDC 2017) and the Sunnybrook Cardiac Magnetic Resonance Imaging (MRI) segmentation challenge. Experimental results show that the mean Dice coefficient of Seg-CapNet is increased by 4.7% and the average Hausdorff distance is reduced by 22%. The proposed model also reduces the model parameters and improves the training speed while obtaining the accurate segmentation of multiple regions. Supplementary Information The online version contains supplementary material available at 10.1007/s11390-021-0782-5.
- Published
- 2021
23. Usefulness of a multiparametric evaluation including global longitudinal strain for an early diagnosis of acute myocarditis
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Marta Focardi, Maria Concetta Pastore, Matteo Cameli, Anna Degiovanni, Giuseppe Patti, and Enrico Guido Spinoni
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Global longitudinal strain ,Adult ,Male ,medicine.medical_specialty ,Myocarditis ,Cardiac magnetic resonance ,Speckle tracking echocardiography ,030204 cardiovascular system & hematology ,Ventricular Function, Left ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,Internal medicine ,White blood cell ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Cardiac imaging ,Speckle tracking ,Retrospective Studies ,Original Paper ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Middle Aged ,medicine.disease ,Acute myocarditis ,medicine.anatomical_structure ,Early Diagnosis ,Echocardiography ,Cardiology ,Population study ,Cardiology and Cardiovascular Medicine ,business - Abstract
Cardiac magnetic resonance imaging (CMRI) represents the main imaging modality for diagnosing acute myocarditis. However, its limited availability could entail missing or delayed diagnosis. A reduction of left ventricular global longitudinal strain (LV GLS) by speckle tracking echocardiography (STE) correlates with amount of oedema in acute myocarditis and here may be early detected. Aim was to evaluate the diagnostic and prognostic role of 3-layers LV GLS in patients with acute myocarditis. Out of 122 patients with suspected acute myocarditis, a total of 86 consecutive patients with CMRI-confirmed acute myocarditis admitted in two Italian institutions were retrospectively screened. Exclusion criteria were met in 29 patients because of poor acoustic window or missing data. A total of 57 patients were then included. Clinical characteristics, laboratory examinations, transthoracic echocardiography data and STE parameters were collected early after hospitalization. In the study population, mean age was 38.8 ± 15.6 years, the prevalence of male gender was 90%. On admission, 22 patients (39%) had fever (body temperature > 37.5 °), mean white blood cell (WBC) count was 10.9 ± 1.7/10^3 and overall LV ejection fraction was 50.1% ± 11.2. An epicardial LV GLS 10.0/10^3 was able to identify all patients with CMRI-diagnosed acute myocarditis. An epicardial LV GLS
- Published
- 2021
24. Underfilling decreases left ventricular function in pulmonary arterial hypertension
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Roger Hesselstrand, Anna Bredfelt, Barbro Kjellström, Ellen Ostenfeld, Göran Rådegran, Hannah Sjögren, Håkan Arheden, and Katarina Steding-Ehrenborg
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medicine.medical_specialty ,Ventricular Function, Left ,Pulmonary hypertension ,Ventricular Dysfunction, Left ,Predictive Value of Tests ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Humans ,Left atrial volume ,Radiology, Nuclear Medicine and imaging ,Pulmonary wedge pressure ,Stroke ,Cardiac imaging ,Original Paper ,Left ventricular dysfunction ,Pulmonary Arterial Hypertension ,Ejection fraction ,Ventricular function ,medicine.diagnostic_test ,business.industry ,Stroke Volume ,Stroke volume ,medicine.disease ,Cardiology ,Feature tracking strain ,Cardiology and Cardiovascular Medicine ,business - Abstract
To evaluate the association between impaired left ventricular (LV) longitudinal function and LV underfilling in patients with pulmonary arterial hypertension (PAH). Thirty-nine patients with PAH and 18 age and sex-matched healthy controls were included. LV volume and left atrial volume (LAV) were delineated in short-axis cardiac magnetic resonance (CMR) cine images. LV longitudinal function was assessed from atrio-ventricular plane displacement (AVPD) and global longitudinal strain (GLS) was assessed using feature tracking in three long-axis views. LV filling was assessed by LAV and by pulmonary artery wedge pressure (PAWP) using right heart catheterisation. Patients had a smaller LAV, LV volume and stroke volume as well as a lower LV-AVPD and LV-GLS than controls. PAWP was 6 [IQR 5––9] mmHg in patients. LV ejection fraction did not differ between groups. LV stroke volume correlated with LV-AVPD (r = 0.445, p = .001), LV-GLS (r = − 0.549, p
- Published
- 2021
25. Prognosis of early pre-discharge and late left ventricular dilatation by cardiac magnetic resonance imaging after acute myocardial infarction
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Maxim Avanesov, Alexander Lenz, Gerhard Adam, Enver Tahir, Gunnar K. Lund, Eric Freiwald, Stefan Blankenberg, Jitka Starekova, Yskert von Kodolitsch, Maythem Saeed, M Sinn, and Kai Muellerleile
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Myocardial Infarction ,Magnetic Resonance Imaging, Cine ,030204 cardiovascular system & hematology ,Ventricular Function, Left ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Percutaneous Coronary Intervention ,0302 clinical medicine ,Predictive Value of Tests ,Cardiac magnetic resonance imaging ,Internal medicine ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Myocardial infarction ,Cardiac imaging ,Original Paper ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Hazard ratio ,Percutaneous coronary intervention ,Stroke Volume ,Left ventricle ,Prognosis ,medicine.disease ,Dilatation ,Magnetic Resonance Imaging ,Patient Discharge ,Conventional PCI ,Cardiology ,ST Elevation Myocardial Infarction ,Female ,Cardiology and Cardiovascular Medicine ,business ,Complication - Abstract
To study the long-term prognosis of early pre-discharge and late left ventricular (LV) dilatation in patients with first ST-elevation myocardial infarction (STEMI) treated by percutaneous coronary intervention (PCI) and contemporary medical therapy. Long-term follow-up > 15 years was available in 53 consecutive patients (55 ± 13 years) with first STEMI. Late gadolinium enhanced (LGE) cardiac magnetic resonance imaging (CMR) was obtained at baseline 5 ± 3 days and follow-up 8 ± 3 months after STEMI to measure LV function, volumes and infarct size. Early pre-discharge dilatation was defined as increased left ventricular end-diastolic volume index (LVEDVi) at baseline CMR with > 97 ml/m2 for males and > 90 ml/m2 for females. Late dilatation was defined as initially normal LVEDVi, which increased ≥ 20% at follow-up. Early dilatation was present in 7 patients (13%), whereas late dilatation occurred in 11 patients (21%). Patients with early LV dilatation had highest mortality (57%), whereas patients with late dilatation had similar mortality (27%) compared to patients without dilatation (26%). Multivariate Cox analysis showed that age (P P P P
- Published
- 2021
26. Evaluation of left ventricular function with cardiac magnetic resonance imaging and echocardiography after administration of dobutamine and esmolol in healthy beagle dogs
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Hyunryung Kim, Jaihyun Jung, Hyounglok Yoon, Youngjae Lee, Dongwoo Chang, Jin Yu, Jinhwa Chang, Hyeryoung Jeong, and Hanbin Lee
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Cardiac function curve ,medicine.medical_specialty ,040301 veterinary sciences ,esmolol ,Ventricular Function, Left ,Propanolamines ,0403 veterinary science ,Contractility ,left ventricular function ,03 medical and health sciences ,Dogs ,Cardiac magnetic resonance imaging ,Internal medicine ,Internal Medicine ,Animals ,Medicine ,030304 developmental biology ,0303 health sciences ,Ejection fraction ,Full Paper ,General Veterinary ,medicine.diagnostic_test ,business.industry ,dobutamine ,Stroke Volume ,Magnetic resonance imaging ,04 agricultural and veterinary sciences ,Stroke volume ,Esmolol ,Magnetic Resonance Imaging ,Echocardiography ,cardiovascular system ,Cardiology ,Dobutamine ,business ,medicine.drug - Abstract
Unlike echocardiography, cardiac magnetic resonance imaging (cardiac MRI) results in a near-exact assessment of cardiac structures and function. However, most veterinary studies have focused on dogs with normal cardiac function. We hypothesized that there would be significant differences in cardiac measurements between cardiac MRI and echocardiography when left ventricular (LV) function was abnormal. This study was undertaken to compare measurements of LV function produced by cardiac MRI and echocardiography in dogs whose LV function was altered by pharmacological agents. This study was conducted with six healthy beagle dogs. We increased left ventricular contractility by administration of dobutamine; we decreased cardiac contractility with esmolol. Stroke volume measurements were made by using both cardiac MRI and echocardiography under seven different conditions with general anesthesia: control, three doses of esmolol (100, 200, and 500 µg/kg/min), and three doses of dobutamine (10, 20, and 50 µg/kg/min). Experiments involving each condition were conducted at least 1 week apart. When LV contractility was normal, ejection fraction (EF) and stroke volume (SV), as measured by echocardiography and cardiac MRI, were not significantly different. However, when contractility was changed by pharmacological agents, EF and SV were overestimated by echocardiography, compared to MRI. Evaluation of cardiac function in patients treated with pharmacological agents should be conducted carefully because EF and SV measured by echocardiography can be overestimated, compared with EF and SV obtained by cardiac MRI.
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- 2021
27. QRS-T angle in patients with Hypertrophic Cardiomyopathy - A comparison with Cardiac Magnetic Resonance Imaging
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Moritz Lambers, Kai Nassenstein, Jan Martin Wambach, Oliver Bruder, Christoph J Jensen, and Behnam Zadeh
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Male ,medicine.medical_specialty ,Medizin ,Contrast Media ,Gadolinium ,Risk Assessment ,cardiovascular magnetic resonance ,Electrocardiography ,03 medical and health sciences ,0302 clinical medicine ,Fibrosis ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Humans ,Late gadolinium enhancement ,In patient ,cardiovascular diseases ,Patient group ,Aged ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Myocardium ,fibrosis ,Hypertrophic cardiomyopathy ,Heart ,General Medicine ,Cardiomyopathy, Hypertrophic ,Middle Aged ,hypertrophic cardiomyopathy ,Prognosis ,medicine.disease ,QRS-T angle ,Magnetic Resonance Imaging ,Qrs t angle ,late gadolinium enhancement ,Disease Progression ,cardiovascular system ,Cardiology ,Female ,030211 gastroenterology & hepatology ,Myocardial fibrosis ,business ,Research Paper ,circulatory and respiratory physiology - Abstract
Objective: We sought to investigate the possible association of a wide QRS-T angle on the surface EKG and myocardial fibrosis on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with hypertrophic cardiomyopathy (HCM). Background: Risk stratification in HCM patients is challenging. Late gadolinium enhancement (LGE) visualizes myocardial fibrosis with unique spatial resolution and is a strong and independent prognosticator in these patients. The QRS-T angle from the surface EKG is a promising prognostic marker in various cardiac pathologies. Methods: 70 patients with HCM obtained a standardized digital 12-lead EKG for the calculation of the QRS-T angle and underwent comprehensive CMR imaging for visualization of fibrosis by LGE. Patients were divided into groups according to the absence or presence of fibrosis on CMR. Results: 43 of 70 patients with HCM showed LGE on CMR following contrast administration. HCM patients with LGE (fibrosis) had wider QRS-T angles as compared to the patient group without LGE (100±54 vs. 46±31
- Published
- 2021
28. Congenital Absence of Pericardium: The Largest Systematic Review in the Field on 247 Worldwide Cases (1977-Now).
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Bassareo, Pier Paolo, Secinaro, Aurelio, Ciliberti, Paolo, Chessa, Massimo, Perrone, Marco Alfonso, Walsh, Kevin Patrick, and Mcmahon, Colin Joseph
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PERICARDIUM ,BUNDLE-branch block ,SYMPTOMS ,ATRIAL septal defects ,CONGENITAL heart disease ,PERICARDITIS - Abstract
Background: Congenital absence of pericardium (CAP), also known as pericardial agenesis, represents an uncommon cardiac abnormality and mostly incidental finding. It can be subdivided into complete and partial (left or right-sided) forms. Because of its infrequency, just case reports and a few case series have been released so far. This paper represents the largest systematic review in the field. Nine features (age at diagnosis, type, gender, clinical presentation, electrocardiography, imaging (ultrasounds, CT/MRI), concomitant cardiac defects, and outcome) were analysed. Methods: The electronic database PubMed was investigated from its establishment up to July 15
th , 2023. Just case reports and case series were included. Animal studies, papers that were not in English, Spanish, and Italian, and those manuscripts not reporting at least seven of the nine analysed features. were ruled out. The analysed data were reported mostly in terms of percentage. Results: One hundred eighty studies were included encompassing 247 patients. More than half of reviewed CAP cases were in males (63.2%). The mean age at diagnosis was 31.8 ± 19.3 years; a range of 32 weeks of gestation-81 years). 23.5% of the patients did not report any symptoms. The most common clinical presentations were chest pain (35.2%) and dyspnoea (29.2%). The most commonly seen ECG changes were right axis deviation (28.7%) and right bundle branch block (23.9%). CAP was suspected or diagnosed by echocardiography in 20.1% of cases. The diagnosis was made by CT and/or MRI in 61.9% of cases. CAP was left-sided in 71.2%, complete in 23.1%, and right-sided in 5.7%. A concomitant congenital heart defect was found in 22.7%, especially in the form of atrial septal defect (6.5%) and patency of ductus arteriosus (2.8%). The pericardial repair was required in 12.9% of the incomplete forms of the disease. Never did the complete form require surgical correction. The outcome appeared favourable in the vast majority of cases, with just 18 deaths (7.3%). Discussion: The main limitation of this systematic review is that it is based just on case reports and case series, due to the lack of large studies on CAP. However, it represents the largest analysis in the field. Due to the rarity of CAP establishing an International Registry is recommended. [ABSTRACT FROM AUTHOR]- Published
- 2023
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- View/download PDF
29. Automated analysis and detection of abnormalities in transaxial anatomical cardiovascular magnetic resonance images: a proof of concept study with potential to optimize image acquisition
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Nick F. Linton, Graham D. Cole, Darrel P. Francis, James P. Howard, Daniel Rueckert, Anil A. Bharath, Kerry Hall, Greg Leonard, Sharon Sutanto, Yousuf Razvi, Vijay Ramadoss, Matthew Shun-Shin, Aaraby Ragavan, Sameer Zaman, and Rosetrees Trust
- Subjects
Cardiomyopathy, Dilated ,Scanner ,medicine.medical_specialty ,Artificial intelligence ,Cardiac & Cardiovascular Systems ,030204 cardiovascular system & hematology ,Convolutional neural network ,Proof of Concept Study ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Automation ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,Machine learning ,Image Interpretation, Computer-Assisted ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,1102 Cardiorespiratory Medicine and Haematology ,Cardiac imaging ,Aorta ,Original Paper ,Science & Technology ,Artificial neural network ,medicine.diagnostic_test ,business.industry ,Deep learning ,Radiology, Nuclear Medicine & Medical Imaging ,Reproducibility of Results ,Magnetic resonance imaging ,Cardiomyopathy, Hypertrophic ,Magnetic Resonance Imaging ,Pleural Effusion ,Nuclear Medicine & Medical Imaging ,Great vessels ,Cardiovascular System & Cardiology ,Radiology ,Neural Networks, Computer ,Cardiology and Cardiovascular Medicine ,business ,Life Sciences & Biomedicine ,Neural networks - Abstract
The large number of available MRI sequences means patients cannot realistically undergo them all, so the range of sequences to be acquired during a scan are protocolled based on clinical details. Adapting this to unexpected findings identified early on in the scan requires experience and vigilance. We investigated whether deep learning of the images acquired in the first few minutes of a scan could provide an automated early alert of abnormal features. Anatomy sequences from 375 CMR scans were used as a training set. From these, we annotated 1500 individual slices and used these to train a convolutional neural network to perform automatic segmentation of the cardiac chambers, great vessels and any pleural effusions. 200 scans were used as a testing set. The system then assembled a 3D model of the thorax from which it made clinical measurements to identify important abnormalities. The system was successful in segmenting the anatomy slices (Dice 0.910) and identified multiple features which may guide further image acquisition. Diagnostic accuracy was 90.5% and 85.5% for left and right ventricular dilatation, 85% for left ventricular hypertrophy and 94.4% for ascending aorta dilatation. The area under ROC curve for diagnosing pleural effusions was 0.91. We present proof-of-concept that a neural network can segment and derive accurate clinical measurements from a 3D model of the thorax made from transaxial anatomy images acquired in the first few minutes of a scan. This early information could lead to dynamic adaptive scanning protocols, and by focusing scanner time appropriately and prioritizing cases for supervision and early reporting, improve patient experience and efficiency. Electronic supplementary material The online version of this article (10.1007/s10554-020-02050-w) contains supplementary material, which is available to authorized users.
- Published
- 2020
30. Quantitative perfusion-CMR is significantly influenced by the placement of the arterial input function
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Christophe T. Arendt, Sina Bremekamp, Diana Brand, Valentina O. Puntmann, Melanie Le, Ibnul Mia, Eike Nagel, and Tommaso D'Angelo
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Signal intensity ,Male ,Ejection fraction ,Contrast Media ,Heart failure ,030204 cardiovascular system & hematology ,Coronary artery disease ,Ventricular Function, Left ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Myocardial perfusion ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,Aortic sinus ,Coronary Circulation ,medicine ,Organometallic Compounds ,Humans ,Radiology, Nuclear Medicine and imaging ,Arterial input function ,Cardiac imaging ,Aortic input function ,Cardiovascular magnetic resonance ,Aged ,Original Paper ,medicine.diagnostic_test ,business.industry ,Myocardial Perfusion Imaging ,Reproducibility of Results ,Stroke Volume ,Middle Aged ,Sinus of Valsalva ,medicine.disease ,Coronary Vessels ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Female ,Cardiology and Cardiovascular Medicine ,business ,Nuclear medicine ,Cardiomyopathies ,Perfusion - Abstract
The aim of this study is to provide a systematic assessment of the influence of the position on the arterial input function (AIF) for perfusion quantification. In 39 patients with a wide range of left ventricular function the AIF was determined using a diluted contrast bolus of a cardiac magnetic resonance imaging in three left ventricular levels (basal, mid, apex) as well as aortic sinus (AoS). Time to peak signal intensities, baseline corrected peak signal intensity and upslopes were determined and compared to those obtained in the AoS. The error induced by sampling the AIF in a position different to the AoS was determined by Fermi deconvolution. The time to peak signal intensity was strongly correlated (r2 > 0.9) for all positions with a systematic earlier arrival in the basal (− 2153 ± 818 ms), the mid (− 1429 ± 928 ms) and the apical slice (− 450 ± 739 ms) relative to the AoS (all p 2 > 0.9 for both) for all positions with a systematic overestimation in all positions relative to the AoS (all p
- Published
- 2020
31. Myocardial involvement and deformation abnormalities in idiopathic inflammatory myopathy assessed by CMR feature tracking
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Carsten Hackenbroch, Dominik Buckert, Peter Bernhardt, Angela Rosenbohm, Meinrad Beer, Albert C. Ludolph, Ahmet Muhammed Güleroglu, and Johannes Kersten
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Cardiac magnetic resonance ,Heart Diseases ,Systole ,Diastole ,Magnetic Resonance Imaging, Cine ,Late gadolinium enhancement ,Ventricular Function, Left ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Cardiac imaging ,Aged ,Original Paper ,Ejection fraction ,medicine.diagnostic_test ,Myositis ,business.industry ,Strain imaging ,Stroke Volume ,Middle Aged ,Idiopathic inflammatory myopathies ,Case-Control Studies ,Idiopathic Inflammatory Myopathy ,Cardiology ,cardiovascular system ,Disease Progression ,Feature tracking ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Cardiac involvement has been described in idiopathic inflammatory myopathies (IIM), including non-specific ECG and echocardiographic findings. Aim of our study was to evaluate myocardial deformation parameters in IIM and to correlate them with late gadolinium enhancement (LGE) findings using cardiac magnetic resonance imaging (CMR). Methods Forty-seven consecutive patients with histologically proven IIM were included into our study. Twenty-five healthy volunteers were used as a control group. All patients and controls underwent CMR examination using a 1.5 T scanner including functional cine and LGE imaging. After a mean follow-up of 234.7 ± 79.5 days a second CMR examination was performed in IIM patients. Results In comparison to healthy volunteers, IIM patients had lower left ventricular mass and left ventricular global radial, circumferential and longitudinal strain. There was no significant difference in left ventricular ejection fraction. Patients with LGE (N = 28) had lower left ventricular ejection fraction (p = 0.016), global right and left ventricular longitudinal strain (p = 0.014 and p = 0.005) and global left ventricular diastolic longitudinal strain rate (p = 0.001) compared to patients without LGE (N = 19). In IIM patients, a significant decrease of left ventricular ejection fraction, left ventricular mass and all measured deformation parameters was observed between baseline and follow-up CMR. Conclusion Cardiac involvement in IIM is frequent. Impairment of systolic and diastolic deformation parameters and a worsening over time can be observed. CMR is a useful tool for cardiac diagnostic work-up of these patients.
- Published
- 2020
32. QRS-T-angle in Patients with ST-Segment Elevation Myocardial Infarction (STEMI) - a Comparison with Cardiac Magnetic Resonance Imaging
- Author
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Kai Nassenstein, Jan Martin Wambach, Moritz Lambers, Oliver Bruder, B. Zadeh, and Christoph J Jensen
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Male ,medicine.medical_specialty ,Medizin ,Contrast Media ,Gadolinium ,Severity of Illness Index ,Coronary artery disease ,cardiovascular magnetic resonance ,Electrocardiography ,03 medical and health sciences ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Humans ,ST segment ,In patient ,cardiovascular diseases ,Myocardial infarction ,Aged ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Heart ,Magnetic resonance imaging ,General Medicine ,Gold standard (test) ,Middle Aged ,medicine.disease ,QRS-T angle ,Magnetic Resonance Imaging ,ST-segment elevation myocardial infarction ,late gadolinium enhancement ,cardiovascular system ,Cardiology ,ST Elevation Myocardial Infarction ,Female ,030211 gastroenterology & hepatology ,business ,Research Paper ,circulatory and respiratory physiology - Abstract
Background: The QRS-T angle from the surface EKG is a promising prognostic marker in patients with coronary artery disease. Cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) offers high resolution imaging of myocardial damage. We investigated the association of the QRS-T angle and the extent of myocardial damage as assessed by LGE in patients with acute ST-segment myocardial infarction (STEMI) Methods: 169 patients with STEMI obtained a standardized digital 12-lead EKG on admission for the calculation of the QRS-T angle and underwent CMR imaging for analysis of infarct size by LGE within the first week. Patients were divided into groups: (1) abnormal QRS-T angle ≥ 90 degree and (2) QRS-T angle < 90 degree. Results: Patients with a QRS-T angle of 90 degree or more had larger infarcts (36.5±12.4 vs. 13.3±9.5; p
- Published
- 2020
33. European Association of Cardiovascular Imaging (EACVI) position paper: multimodality imaging in pericardial disease.
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Cosyns, Bernard, Plein, Sven, Nihoyanopoulos, Petros, Smiseth, Otto, Achenbach, Stephan, Andrade, Maria Joao, Pepi, Mauro, Ristic, Arsen, Imazio, Massimo, Paelinck, Bernard, and Lancellotti, Patrizio
- Subjects
HEART disease diagnosis ,COMPUTED tomography ,ECHOCARDIOGRAPHY ,MAGNETIC resonance imaging ,PERICARDIUM - Abstract
Although pericardial diseases are common in the daily clinical practice and can result in a significant morbidity and mortality, imaging of patients with suspected or known pericardial disorders remain challenging. Multimodality imaging is part of the management of pericardial diseases. Echo-cardiography, cardiac computed tomography, and cardiovascular magnetic resonance are often used as complementary imaging modalities. The choice of one or multiple imaging modalities is driven by the clinical context or conditions of the patient. The scope of the present document is to highlight the respective role of each technique according to the clinical context in the diagnosis and management of pericardial diseases. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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- View/download PDF
34. Reduction in left atrial and pulmonary vein dimensions after ablation therapy is mediated by scar
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Nora Al Jefairi, Jérôme Lamy, Hubert Cochet, Nadjia Kachenoura, Dounia El Hamrani, Bruno Quesson, Lukas R.C. Dekker, Ruben Coronel, Lisa A. Gottlieb, Marion Constantin, Jérôme Naulin, Graduate School, Cardiology, and ACS - Heart failure & arrhythmias
- Subjects
medicine.medical_specialty ,Cardiac magnetic resonance ,medicine.medical_treatment ,Pulmonary vein isolation ,Pulmonary vein ,Contractility ,Left atrial ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Sinus rhythm ,Ablation scar ,Reduction (orthopedic surgery) ,Original Paper ,medicine.diagnostic_test ,business.industry ,Atrial fibrillation ,medicine.disease ,Ablation ,Atrial contractility ,RC666-701 ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Graphical abstract The reduction in LA and PV dimensions after ablation. Clinically successful PVI ablation decreased the PV and LA dimensions in AF patients (left panel). We make observations (right panel) that are compatible with the direct effect of ablation energy and subsequent scar formation causing the atrial downsizing., Background Ablative pulmonary vein isolation (PVI) decreases pulmonary vein (PV) and left atrial (LA) dimensions in atrial fibrillation (AF) patients. These changes are attributed to reverse structural remodeling following sinus rhythm restoration but evidence is lacking. We hypothesized that the downsizing is directly caused by the ablative energy and subsequent scar formation. Methods We studied cardiac magnetic resonance imaging in 21 paroxysmal AF patients before and 3 months after successful PVI and in healthy sheep (n = 12) before and after PVI of the right PV only. Results PVI decreased the PV diameter in patients and sheep by 11.0(10.3) and 9.2(11.0)%, (p
- Published
- 2021
35. Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardial infarction: A post-hoc analysis of the AVOID study
- Author
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Paul S. Myles, Karlheinz Peter, David M. Kaye, Peter Cameron, Michael Stephenson, Andris H. Ellims, Andrew J. Taylor, Romi Stub, Janet Bray, Karen Smith, Stephen Bernard, Himawan Fernando, Dion Stub, and Ziad Nehme
- Subjects
medicine.medical_specialty ,Heart disease ,medicine.medical_treatment ,Chest pain ,Culprit ,Infarct size ,Opioid analgesia ,Chest pain predictors ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Myocardial infarction ,Original Paper ,medicine.diagnostic_test ,business.industry ,Chronic pain ,Percutaneous coronary intervention ,Retrospective cohort study ,medicine.disease ,RC666-701 ,Cardiology ,Pain severity ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background We sought to determine if an association exists between prehospital chest pain severity and markers of myocardial injury. Methods and Results Patients with confirmed ST elevation myocardial infarction (STEMI) treated by emergency medical services were included in this retrospective cohort analysis of the AVOID study. The primary endpoint was the association of pre-hospital initial chest pain severity, cardiac biomarkers and infarct size based on cardiac magnetic resonance imaging. Groups were categorized based on moderate to severe chest pain (numerical rating scale pain ≥ 5/10) or less than moderate severity to compare procedural and clinical outcomes. 414 patients were included in the analysis. There was a weak correlation between initial pre-hospital chest pain severity and peak creatine kinase (r = 0.16, p = 0.001) and peak cardiac troponin I (r = 0.14, p = 0.005). Both were no longer significant after adjusting for known confounders. There was no association between moderate to severe chest pain on arrival and major adverse cardiac events at 6 months (20% vs. 14%, p=0.12). There was a weak correlation between history of ischemic heart disease (r = 0.16, p = 0.001), percutaneous coronary intervention (r = 0.16, p = 0.001), left anterior descending artery (r = 0.12, p = 0.012) as the culprit vessel and a weak negative correlation between age (r = -0.14, p = 0.039) and chest pain. Conclusion Only a weak association between pre-hospital chest pain severity and markers of myocardial injury was identified, supporting more judicious use of opioid analgesia with a focus on patient comfort.
- Published
- 2021
36. Right ventricular volume and its relationship to functional tricuspid regurgitation
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Sophie M. Offen, David Baker, Raj Puranik, and David S. Celermajer
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Original Paper ,RC666-701 ,cardiovascular system ,Diseases of the circulatory (Cardiovascular) system ,Right ventricle ,Cardiology and Cardiovascular Medicine ,Cardiac magnetic resonance imaging ,Functional tricuspid regurgitation - Abstract
Background: Significant right ventricular (RV) dilatation has long been considered integral to the pathogenesis of functional tricuspid regurgitation (FTR). Objectives: To explore the relationship of RV dilatation and FTR in patients with ‘pure’ RV volume overload. Methods: Patients (>17yrs) with RV dilatation due to pre-tricuspid shunts (atrial septal defect; ASD and/or partial anomalous pulmonary venous drainage; PAPVD) referred to our service (2000–2019) were retrospectively identified. Those with pulmonary hypertension, primum ASD or left-heart disease were excluded. Using standard cardiac MRI protocols, RV, right atrial and TV parameters were measured and compared. Results: Of 52 consecutively eligible patients (42 ± 15yrs, 25 males), 25 had ASDs, 13 had PAPVD and 14 had both conditions. All were in sinus rhythm and none had pulmonary regurgitation. Left and right ventricular ejection fractions were normal (LVEF 63 ± 8%, RVEF 56 ± 8%). Indexed RV end-diastolic volumes (RVEDVi) were moderately increased (males 148 ± 33 mL/m2 and females 141 ± 42 mL/m2, range 95–267 mL/m2). Despite substantial RV volume overload, no patients had severe tricuspid regurgitation (TR). Only two had > mild TR. There was a weak correlation between tricuspid annular diameter and both degree of RV dilatation (r = 0.37; p = 0.01) and degree of TR (r = 0.38; p = 0.006). There was a similarly poor correlation between right atrial dimensions and the degree of TR (r = 0.34; p = 0.02). Conclusion: When RV dilatation is simply due to volume overload, we find that significant TR is extremely rare. This gives an important and novel insight; that RV dilatation per se does not result in FTR.
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- 2021
37. Interventional cardiac magnetic resonance imaging: current applications, technology readiness level, and future perspectives.
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Rier, Sophie C., Vreemann, Suzan, Nijhof, Wouter H., van Driel, Vincent J.H.M., and van der Bilt, Ivo A.C.
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CARDIAC magnetic resonance imaging ,TECHNOLOGY assessment ,MAGNETIC resonance imaging ,TECHNOLOGICAL innovations ,CARDIAC catheterization - Abstract
Background: Cardiac magnetic resonance (CMR) provides excellent temporal and spatial resolution, tissue characterization, and flow measurements. This enables major advantages when guiding cardiac invasive procedures compared with X-ray fluoroscopy or ultrasound guidance. However, clinical implementation is limited due to limited availability of technological advancements in magnetic resonance imaging (MRI) compatible equipment. A systematic review of the available literature on past and present applications of interventional MR and its technology readiness level (TRL) was performed, also suggesting future applications. Methods: A structured literature search was performed using PubMed. Search terms were focused on interventional CMR, cardiac catheterization, and other cardiac invasive procedures. All search results were screened for relevance by language, title, and abstract. TRL was adjusted for use in this article, level 1 being in a hypothetical stage and level 9 being widespread clinical translation. The papers were categorized by the type of procedure and the TRL was estimated. Results: Of 466 papers, 117 papers met the inclusion criteria. TRL was most frequently estimated at level 5 meaning only applicable to in vivo animal studies. Diagnostic right heart catheterization and cavotricuspid isthmus ablation had the highest TRL of 8, meaning proven feasibility and efficacy in a series of humans. Conclusion: This article shows that interventional CMR has a potential widespread application although clinical translation is at a modest level with TRL usually at 5. Future development should be directed toward availability of MR-compatible equipment and further improvement of the CMR techniques. This could lead to increased TRL of interventional CMR providing better treatment. [ABSTRACT FROM AUTHOR]
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- 2022
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38. Cardiovascular magnetic resonance in the identification of extra-cardiac causes of myocarditis: a case series.
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Sakhi, Hichem, Reverdito, Guillaume, Soulat, Gilles, and Mousseaux, Elie
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LIVER abscesses ,MAGNETIC resonance ,PYOGENIC liver abscess ,MYOCARDITIS ,CARDIAC magnetic resonance imaging - Abstract
Background Myocarditis is challenging to diagnose due to its varied presentations. Endomyocardial biopsy is the gold standard for diagnosis, but its invasive nature has led to alternative non-invasive modalities, notably cardiovascular magnetic resonance (CMR). Identifying the precise aetiology of myocarditis is crucial for effective treatment, yet extra-cardiac causes are often overlooked. In this paper, we spotlight the underexplored role of CMR in diagnosing extra-cardiac aetiologies, utilizing three insightful cases for illustration. Case summary The first case is a 31-year-old patient with myocarditis secondary to a pyogenic liver abscess, identified through CMR, who improved after abscess drainage. The second case involves a 54-year-old patient with myocarditis attributed to adult T-cell leukaemia–lymphoma, with the loco-regional thickening process identified thanks to CMR. This patient had an unfavourable disease progression due to the underlying malignancy. The third case concerns a 23-year-old patient suffering from myocarditis associated with pneumonia, again illustrated effectively through CMR imaging, who recovered after antibiotic treatment. Discussion These cases underline the overlooked potential of CMR in diagnosing extra-cardiac aetiologies of myocarditis, even though such causes are rare. Despite current guidelines recognizing the importance of identifying the aetiology of myocarditis, they do not explicitly address the role of CMR in diagnosing extra-cardiac aetiologies. This article, therefore, proposes that future guidelines could emphasize the utility of CMR in exploring these causes, potentially leading to more accurate diagnoses and improved patient outcomes. It also advocates for a comprehensive, multidisciplinary approach to myocarditis diagnosis, encouraging vigilance for potential loco-regional causes, and calls for further research in this area. [ABSTRACT FROM AUTHOR]
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- 2024
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39. IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement.
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Houshmand, Golnaz, Moosavi, Najme-Sadat, Shahbazkhani, Amirhossein, and Pouraliakbar, Hamidreza
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LITERATURE reviews ,CARDIAC magnetic resonance imaging ,CARDIOVASCULAR system ,SYMPTOMS - Abstract
Background: IgG4-related disease is a fibro-inflammatory disorder with an unknown etiology, which can affect multiple organ systems, including the cardiovascular system. While most reported cases of cardiovascular involvement are primarily associated with the aorta, there have been sporadic reports of isolated cardiac involvement. Case presentation: This paper presents a documented case of IgG4-related systemic disease with symptoms indicative of restrictive cardiomyopathy. Subsequent Cardiac Magnetic Resonance imaging revealed diffuse myopericardial involvement, characterized by pericardial thickening and enhancement, accompanied by subepicardial and myocardial infiltration. Considering the rarity of cardiac involvement in our case, we conducted a thorough review of the existing literature pertaining to various patterns of cardiac involvement in IgG4-related disease, as well as the diagnostic modalities that can be employed for accurate identification and assessment. Conclusions: This case report sheds light on the importance of recognizing and evaluating cardiac manifestations in IgG4-related systemic disease to facilitate timely diagnosis and appropriate management. [ABSTRACT FROM AUTHOR]
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- 2024
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40. DECTNet: Dual Encoder Network combined convolution and Transformer architecture for medical image segmentation.
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Li, Boliang, Xu, Yaming, Wang, Yan, and Zhang, Bo
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CONVOLUTIONAL neural networks ,TRANSFORMER models ,DIAGNOSTIC imaging ,DEEP learning ,IMAGE segmentation ,CARDIAC magnetic resonance imaging ,THERAPEUTICS - Abstract
Automatic and accurate segmentation of medical images plays an essential role in disease diagnosis and treatment planning. Convolution neural networks have achieved remarkable results in medical image segmentation in the past decade. Meanwhile, deep learning models based on Transformer architecture also succeeded tremendously in this domain. However, due to the ambiguity of the medical image boundary and the high complexity of physical organization structures, implementing effective structure extraction and accurate segmentation remains a problem requiring a solution. In this paper, we propose a novel Dual Encoder Network named DECTNet to alleviate this problem. Specifically, the DECTNet embraces four components, which are a convolution-based encoder, a Transformer-based encoder, a feature fusion decoder, and a deep supervision module. The convolutional structure encoder can extract fine spatial contextual details in images. Meanwhile, the Transformer structure encoder is designed using a hierarchical Swin Transformer architecture to model global contextual information. The novel feature fusion decoder integrates the multi-scale representation from two encoders and selects features that focus on segmentation tasks by channel attention mechanism. Further, a deep supervision module is used to accelerate the convergence of the proposed method. Extensive experiments demonstrate that, compared to the other seven models, the proposed method achieves state-of-the-art results on four segmentation tasks: skin lesion segmentation, polyp segmentation, Covid-19 lesion segmentation, and MRI cardiac segmentation. [ABSTRACT FROM AUTHOR]
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- 2024
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41. Cardiac MRI-Derived Inferior Vena Cava Cross-Sectional Area Correlates with Measures of Fontan-Associated Liver Disease.
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Gunsaulus, Megan, Wang, Li, Haack, Lindsey, Christopher, Adam, Feingold, Brian, Squires, James, Horslen, Simon, Hoskoppal, Arvind, Rose-Felker, Kirsten, West, Shawn, Trucco, Sara, Squires, Judy, Olivieri, Laura, Kreutzer, Jacqueline, Goldstein, Bryan, and Alsaied, Tarek
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VENA cava inferior ,LIVER diseases ,CARDIAC magnetic resonance imaging ,CIRRHOSIS of the liver ,MEDICAL screening - Abstract
There is currently no clear consensus on screening techniques to evaluate the presence or severity of Fontan-associated liver disease (FALD). Cardiac MRI (CMR) is used routinely for post-Fontan surveillance, but CMR-derived measures that relate to the severity of FALD are not yet defined. This was a cross-sectional single-center study of post-Fontan patients who underwent a CMR. CMR exams were re-analyzed by a single pediatric cardiologist. Surrogates of FALD included Gamma-Glutamyl Transferase (GGT), Fibrosis-4 laboratory score (FIB-4), and imaging findings. Findings consistent with cirrhosis on liver ultrasound included increased liver echogenicity and/or nodularity. Statistical analyses were performed to investigate potential relationships between CMR parameters and markers of FALD. Sixty-one patients were included. A larger inferior vena cava cross-sectional area (IVC-CSA) indexed to height was significantly associated with a higher FIB-4 score (Spearman's ρ = 0.28, p = 0.04), a higher GGT level (Spearman's ρ = 0.40, p = 0.02), and findings consistent with cirrhosis on liver ultrasound (OR 1.17, 95% CI: (1.01, 1.35), p = 0.04). None of the other CMR parameters were associated with markers of FALD. A larger indexed IVC-CSA was associated with higher systemic ventricle end-diastolic pressure (EDP) on cardiac catheterization (Spearman's ρ = 0.39, p = 0.018) as well as older age (Spearman's ρ = 0.46, p = < 0.001). Indexed IVC-CSA was the only CMR parameter that was associated with markers of FALD. This measure has the potential to serve as an additional non-invasive tool to improve screening strategies for FALD. Visual abstract summarizing the primary findings of this paper [ABSTRACT FROM AUTHOR]
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- 2024
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42. Importance of Multimodality Cardiac Imaging in the Diagnosis of Lipomatous Hypertrophy of the Interatrial Septum—A View beyond Standard Situations.
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Șoșdean, Raluca, Lazăr, Mihai-Andrei, Pescariu, Silvius Alexandru, Mircea, Monica-Nicoleta, Lala, Radu Ioan, Mornoș, Cristian, Luca, Constantin Tudor, and Ionac, Adina
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ATRIAL septum ,CARDIAC imaging ,LUNGS ,CARDIAC magnetic resonance imaging ,TRANSESOPHAGEAL echocardiography ,DIAGNOSIS ,ATRIAL flutter - Abstract
Lipomatous hypertrophy of the interatrial septum (LHIAS) represents a benign proliferation of lipoid cells at the level of the interatrial septum (IAS) inducing an important thickening of this structure. It respects the fossa ovalis (FO) region, having a typical "hourglass" echocardiographic appearance. There are certain cases though, with unusual appearances and/or with associated pathologies that may induce similar lesions in the heart, in which the differential diagnosis cannot be guaranteed using only the standard methods. The final diagnosis has important implications in these patients' treatment plan. In this paper, we present an unusual case of a female patient undergoing chemotherapy for lung carcinoma, suspected of right atrial thrombosis/metastasis. As the diagnosis was unclear after transthoracic echocardiography (TTE), inducing the suspicion of an IAS mass with atrial wall infiltration, bi- and tridimensional transesophageal echocardiography (TOE) was performed, revealing a severely and homogenously hypertrophied IAS respecting the FO, but lacking a clear visualization of the atrial wall. The diagnosis of LHIAS was established by cardiac magnetic resonance (CMR) that certified the adipose nature of the structure, excluding the need for invasive investigations and/or treatment options. Multimodality imaging is very important for the clinician in adopting the best management plan for each individual patient. [ABSTRACT FROM AUTHOR]
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- 2024
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43. Clinical effectiveness of a dedicated cardiac resynchronization therapy pre-assessment clinic incorporating cardiac magnetic resonance imaging and cardiopulmonary exercise testing on patient selection and outcomes
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Mark K. Elliott, Christopher A. Rinaldi, Gerald Carr-White, Justin Gould, Vishal Mehta, Steven A. Niederer, and Baldeep S. Sidhu
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medicine.medical_specialty ,Composite score ,genetic structures ,Clinical effectiveness ,medicine.medical_treatment ,Cardiac resynchronization therapy ,Heart failure ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Internal medicine ,health services administration ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Review process ,030212 general & internal medicine ,cardiovascular diseases ,Original Paper ,medicine.diagnostic_test ,business.industry ,Cardiopulmonary exercise testing ,medicine.disease ,RC666-701 ,Cardiology ,cardiovascular system ,Cardiology and Cardiovascular Medicine ,Cardiac magnetic resonance ,business ,circulatory and respiratory physiology - Abstract
Background Pre-procedural assessment of patients undergoing cardiac resynchronization therapy (CRT) is heterogenous and patients implanted with unfavorable characteristics may account for non-response. A dedicated CRT pre-assessment clinic (CRT PAC) was developed to standardize the review process and undertake structured pre-procedural evaluation. The aim of this analysis was to determine the effectiveness on patient selection and outcomes. Methods A prospective database of consecutive patients attending the CRT PAC between 2013 and 2018 was analyzed. Pre-operative assessment included cardiac magnetic resonance (CMR) and cardiopulmonary exercise testing (CPET). Patients were considered CRT responders based on improvement in clinical composite score (CCS) and/or reduction in left ventricular end-systolic volume (LVESV) ≥ 15% at 6-months follow-up. Results Of 252 patients reviewed in the CRT PAC during the analysis period, 192 fulfilled consensus guidelines for implantation. Of the patients receiving CRT, 82% showed improvement in their CCS and 57% had a reduction in LVESV ≥ 15%. The presence of subendocardial scar on CMR and a peak VO2 ≤ 12 ml/kg/min on CPET predicted CRT non-response. Two patients were unsuitable for CRT as they had end-stage heart failure and died during follow-up. The majority of patients initially deemed unsuitable for CRT did not suffer from unexpected hospitalization for decompensated heart failure or died from cardiovascular disease; only 8 patients (13%) received CRT devices during follow-up because of symptomatic left ventricular systolic impairment. Conclusion A dedicated CRT PAC is able to appropriately select patients for CRT. Pre-procedural investigation/imaging can identify patients unlikely to respond to, or may not yet be suitable for CRT.
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- 2021
44. Impact of age on reperfusion success and long-term prognosis in ST-segment elevation myocardial infarction – A cardiac magnetic resonance imaging study
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Henning Kelbæk, Divan Gabriel Topal, Kasper Kyhl, Frants Pedersen, Kiril Aleksov Ahtarovski, Renate B. Schnabel, Peter Clemmensen, Mikkel Malby Schoos, Lars Nepper-Christensen, Dan Eik Høfsten, Jacob Lønborg, Thomas Engstrøm, Lars Køber, Steffen Helqvist, Christoffer Göransson, Litten Bertelsen, Lene Holmvang, Niels Vejlstrup, and Adam Ali Ghotbi
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medicine.medical_specialty ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Culprit ,Collaterals, Collateral coronary circulation ,Percutaneous coronary intervention ,03 medical and health sciences ,0302 clinical medicine ,Age ,Magnetic resonance imaging ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Diseases of the circulatory (Cardiovascular) system ,ST segment ,PCI, Percutaneous coronary intervention ,030212 general & internal medicine ,Myocardial infarction ,cardiovascular diseases ,CMR, Cardiac magnetic resonance ,Original Paper ,DANAMI-3, The Third Danish study on Acute Myocardial Infarction ,Ejection fraction ,TIMI, Thrombolysis in myocardial infarction ,medicine.diagnostic_test ,business.industry ,ECG, Electrocardiogram ,MVO, Microvascular obstruction ,Hazard ratio ,STEMI, ST-segment elevation myocardial infarction ,medicine.disease ,LVEF, Left ventricular ejection fraction ,ST-segment elevation myocardial infarction ,RC666-701 ,Heart failure ,Cardiology ,cardiovascular system ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: Coronary collateral circulation and conditioning from remote ischemic coronary territories may protect culprit myocardium in the elderly, and younger STEMI patients could suffer from larger infarcts. We evaluated the impact of age on myocardial salvage and long-term prognosis in a contemporary STEMI cohort. Methods: Of 1603 included STEMI patients 807 underwent cardiac magnetic resonance. To assess the impact of age on infarct size and left ventricular ejection fraction (LVEF) as well as the composite endpoint of death and re-hospitalization for heart failure we stratified the patients by an age cut-off of 60 years. Results: Younger STEMI patients had smaller final infarcts (10% vs. 12%, P = 0.012) and higher final LVEF (60% vs. 58%, P = 0.042). After adjusting for multiple potential confounders age did not remain significantly associated with infarct size and LVEF. During 4-year follow-up, the composite endpoint occurred less often in the young (3.2% vs. 17.2%; P < 0.001) with a univariate hazard ratio of 5.77 (95% CI, 3.75–8.89; p < 0.001). Event estimates of 4 subgroups (young vs. elderly and infarct size beyond vs. below median) showed a gradual increase in the occurrence of the composite endpoint depending on both age and acute infarct size (log-rank p < 0.001). Conclusion: Having a STEMI after entering the seventh decade of life more than quadrupled the risk of future death or re-hospitalization for heart failure. Risk of death and re-hospitalization depended on both advanced age and infarct size, albeit no substantial difference was found in infarct size, LVEF and salvage potential between younger and elderly patients with STEMI.
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- 2021
45. Validation of simple measures of aortic distensibility based on standard 4-chamber cine CMR: a new approach for clinical studies
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Marcus Kelm, Rolf Gebker, Christian Stehning, Volkmar Falk, Niky Ghorbani, Burkert Pieske, Nina Rank, Sebastian Kelle, Titus Kuehne, Lukas Stoiber, and Tomas Lapinskas
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Male ,medicine.medical_specialty ,Cine MRI ,Magnetic Resonance Imaging, Cine ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Vascular Stiffness ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,medicine.artery ,Internal medicine ,medicine ,Humans ,Aortic distensibility ,Compliance ,Reproducibility ,030212 general & internal medicine ,Aorta ,Retrospective Studies ,Observer Variation ,Original Paper ,medicine.diagnostic_test ,business.industry ,Reproducibility of Results ,General Medicine ,Middle Aged ,Cine mri ,Rapid assessment ,Sample size determination ,Descending aorta ,cardiovascular system ,Cardiology ,Aortic stiffness ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Objective Aortic distensibility (AD) represents a well-established parameter of aortic stiffness. It remains unclear, however, whether AD can be obtained with high reproducibility in standard 4-chamber cine CMR images of the descending aorta. This study investigated the intra- and inter-observer agreement of AD based on different angles of the aorta and provided a sample size calculation of AD for future trials. Methods Thirty-one patients underwent CMR. Angulation of the descending aorta was performed to obtain strictly transversal and orthogonal cross-sectional aortic areas. AD was obtained both area and diameter based. Results For area-based values, inter-observer agreement was highest for 4-chamber AD (ICC 0.97; 95% CI 0.93–99), followed by orthogonal AD (ICC 0.96; 95% CI 0.91–98) and transversal AD (ICC 0.93; 95% CI 0.80–97). For diameter-based values, agreement was also highest for 4-chamber AD (ICC 0.97; 95% CI 0.94–99), followed by orthogonal AD (ICC 0.96; 95% CI 0.92–98) and transversal AD (ICC 0.91; 95% CI 0.77–96). Bland–Altman plots confirmed a small variation among observers. Sample size calculation showed a sample size of 12 patients to detect a change in 4-chamber AD of 1 × 10−3 mmHg−1 with either the area or diameter approach. Conclusion AD measurements are highly reproducible and allow an accurate and rapid assessment of arterial compliance from standard 4-chamber cine CMR., Clinical Research in Cardiology, 109 (4)
- Published
- 2019
46. Cardiac Magnetic Resonance Imaging in Patients with Acute Ischemic Stroke and Elevated Troponin: A TRoponin ELevation in Acute Ischemic Stroke (TRELAS) Sub-Study
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Matthias Endres, Bernhard Witzenbichler, Christian H. Nolte, Heinrich J. Audebert, Thomas Krause, Christian Wollboldt, Jan F. Scheitz, Christoph J Jensen, Hans-Christian Mochmann, Ulf Landmesser, Jochen B. Fiebach, and Karl Georg Haeusler
- Subjects
Male ,blood [Troponin T] ,lcsh:Diseases of the circulatory (Cardiovascular) system ,Coronary angiography ,Myocardial Infarction ,030204 cardiovascular system & hematology ,Coronary Angiography ,Severity of Illness Index ,Brain Ischemia ,Coronary artery disease ,0302 clinical medicine ,Interquartile range ,diagnostic imaging [Stroke] ,complications [Stroke] ,Prospective Studies ,Myocardial infarction ,blood [Brain Ischemia] ,Stroke ,Aged, 80 and over ,blood [Biomarkers] ,medicine.diagnostic_test ,biology ,complications [Brain Ischemia] ,Middle Aged ,Magnetic Resonance Imaging ,Up-Regulation ,Neurology ,diagnostic imaging [Coronary Stenosis] ,Cardiology ,Female ,Acute coronary syndrome ,Cardiology and Cardiovascular Medicine ,medicine.medical_specialty ,blood [Myocardial Infarction] ,03 medical and health sciences ,Magnetic resonance imaging ,Troponin T ,blood [Coronary Stenosis] ,Predictive Value of Tests ,Cardiac magnetic resonance imaging ,Internal medicine ,diagnostic imaging [Myocardial Infarction] ,medicine ,Humans ,ddc:610 ,Aged ,Original Paper ,business.industry ,Coronary Stenosis ,Reproducibility of Results ,complications [Coronary Stenosis] ,medicine.disease ,Troponin ,blood [Stroke] ,diagnostic imaging [Brain Ischemia] ,lcsh:RC666-701 ,biology.protein ,Neurology (clinical) ,complications [Myocardial Infarction] ,business ,Biomarkers ,030217 neurology & neurosurgery - Abstract
Background: Elevated high-sensitive cardiac troponin (hs-cTn) can be found in more than 50% of the patients with acute ischemic stroke. The observational TRoponin ELevation in Acute ischemic Stroke (TRELAS) study revealed that about 25% of all stroke patients with elevated troponin had a coronary angiography-detected culprit lesion affording immediate intervention, and about 50% of all patients did not have any obstructive coronary artery disease. Given the risk of procedure-related complications, the identification of stroke patients in urgent need of invasive coronary angiography is desirable. Methods: TRELAS patients were prospectively enrolled into this sub-study. In addition to conventional coronary angiography, a cardiac magnetic resonance imaging (MRI) at 3T was performed during the in-hospital stay after acute ischemic stroke to compare the diagnostic value of both imaging modalities. Results:Nine stroke patients (median age 73 years [range 58–87]; four females; median NIH Stroke Severity score on admission 4 [range 0–6] with elevated hs-cTnT [median 74 ng/L, interquartile range 41–247] on admission) completed cardiac MRI and underwent coronary angiography. The absence of MRI-detected wall motion abnormalities and/or late gadolinium enhancement in 5 stroke patients corresponded with the exclusion of culprit lesions or significant coronary artery disease by coronary angiography. Four patients had abnormal MRI findings, whereof 2 showed evidence of myocardial infarction and in whom coronary angiography demonstrated a >70% stenosis of a coronary artery. Conclusions: The TRELAS sub-study indicates that noninvasive cardiac MRI may provide helpful information to identify stroke patients with or without acute coronary syndrome. Our findings might help to select stroke patients in urgent need of coronary angiography.
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- 2019
47. Left ventricular reverse remodeling in patients with anterior wall ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention
- Author
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Magdalena Kocierz-Woźnowska, Marcin Wita, Krystian Wita, Marek Grabka, Maciej Turski, Katarzyna Mizia-Stec, and Maciej T. Wybraniec
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medicine.medical_specialty ,3D transthoracic echocardiography ,medicine.medical_treatment ,cardiac magnetic resonance imaging ,lcsh:Medicine ,030204 cardiovascular system & hematology ,Revascularization ,reverse remodeling ,03 medical and health sciences ,0302 clinical medicine ,anterior global longitudinal strain ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,ST segment ,acute myocardial infarction/ST-segment elevation myocardial infarction ,Myocardial infarction ,Original Paper ,medicine.diagnostic_test ,biology ,business.industry ,lcsh:R ,Percutaneous coronary intervention ,medicine.disease ,Troponin ,030228 respiratory system ,Conventional PCI ,Cardiology ,biology.protein ,Cardiology and Cardiovascular Medicine ,business ,Mace ,global longitudinal strain - Abstract
Introduction The study aimed to evaluate the prevalence and predictors of left ventricular (LV) reverse remodeling and its impact on long-term prognosis in patients with anterior ST-segment elevation myocardial infarction (STEMI). Aim To assess the percentage of reverse remodeling and its prognostic factors in anterior STEMI patients. Material and methods This observational study included 40 patients with first ever STEMI of the anterior wall. LV reverse remodeling was defined as the reduction of left ventricular end-systolic volume (ΔLVESV) by ≥ 10% in 3D transthoracic echocardiography (3D-TTE) at 3-month follow-up. 3D-TTE and speckle tracking imaging were performed during index hospitalization, while 3D-TTE and cardiac magnetic resonance (CMR) were performed at 3 months following the procedure. Patients were followed up for a median time of 3.4 years in order to evaluate major adverse cardiovascular events. Results Left ventricular reverse remodeling at 3-month follow-up was confirmed in 15 (37.5%) patients. The presence of reverse remodeling was predicted by lower troponin levels (unit OR = 0.86, p = 0.02), lower sum of ST-segment elevations before (unit OR = 0.87, p = 0.03) and after PCI (unit OR = 0.40, p = 0.03), lower maximal ST-segment elevation after PCI (unit OR = 0.01, p = 0.03), lower wall motion score index (unit OR 0.40, p = 0.03) and more negative anterior wall global longitudinal strain (unit OR = 0.88, p = 0.045). Nine MACE were reported in the without reverse remodeling group only. Non-significantly better event-free survival in the reverse remodeling group was demonstrated (log-rank p = 0.07). Conclusions Development of reverse modeling in patients with optimal revascularization and tailored pharmacotherapy is relatively high. Further studies are warranted in order to adjudicate its prognostic role for the prediction of adverse events.
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- 2018
48. Prevalence and clinical significance of incidental extracardiac findings in cardiac magnetic resonance imaging
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Narumol Chaosuwannakit and Pattarapong Makarawate
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Thorax ,medicine.medical_specialty ,Original Paper ,medicine.diagnostic_test ,business.industry ,Significant group ,cardiac magnetic resonance imaging ,Cardiac magnetic resonance imaging ,cardiovascular system ,Medicine ,Surgery ,Clinical significance ,In patient ,Medical history ,Radiology ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine ,business ,Upper abdomen ,Pathological ,extracardiac findings - Abstract
Incidental pathological findings are frequently found outside the investigated cardiovascular system in cardiac magnetic resonance (CMR) imaging. Some of these findings might have clinical importance.To evaluate the prevalence and significance of extracardiac findings (ECFs) in patients referred for CMR. The CMR has the ability to depict ECFs in the visualized thorax and upper abdomen. These incidental lesions can often present a challenge to physicians.A total of 192 CMR reports were retrospectively reviewed for extracardiac findings. ECFs were classified as benign, indeterminate, or of clinical significance at the time of image evaluation. Benign findings were those considered to be of little clinical significance with no follow-up needed. Indeterminate findings were those deemed of potential clinical importance, requiring correlation of the patient history or a follow-up study. Clinically significant findings were those felt to be of definite clinical importance requiring immediate evaluation or intervention.A total of 56 (29.2%) ECFs were found in 192 (29.2%) patients. Of those, 21 (37.5%) were considered benign, 23 (41%) indeterminate, and 12 (21.4%) clinically significant findings. In the clinically significant group, the most common findings were liver and pulmonary masses. Five malignancies were observed with certainty at CMR. All of them had been incidentally diagnosed on CMR for the first time, and the patients' management was subsequently changed.Extracardiac findings in clinically indicated CMR are common in the present study (about 29.2%). Radiologists and cardiologists should be aware of relevant extracardiac findings that might require additional diagnostics or treatment.Ocena występowania i znaczenia przypadkowych znalezisk pozakardiologicznych (ECF) u pacjentów skierowanych na badanie rezonansu magnetycznego serca (CMR). Badanie CMR umożliwia wykrycie zmian pozakardiologicznych w klatce piersiowej i górnej części jamy brzusznej. Zmiany te często stanowią wyzwanie dla lekarzy.Badaniu retrospektywnemu poddano ogółem 192 obrazy CMR pod kątem zmian pozakardiologicznych. Zmiany te klasyfikowano jako łagodne, nieokreślone lub istotne klinicznie w czasie oceny. Zmiany łagodne to zmiany o niewielkiej istotności klinicznej, niewymagajace obserwacji. Zmianami nieokreślonymi nazywa się zmiany potencjalnie istotne klinicznie, które wymagają zestawienia z historią pacjenta lub obserwacji, natomiast istotnymi klinicznie – zmiany, które mają określone znaczenie kliniczne i wymagają natychmiastowej oceny lub interwencji.Stwierdzono ogółem 56 (29,2%) zmian pozakardiologicznych u 192 pacjentów, z czego 21 (37,5%) uznano za łagodne, 23 (41%) – nieokreślone, a 12 (21,4%) – klinicznie istotne. W grupie zmian klinicznie istotnych najczęściej obserwowano masy w wątrobie lub płucach. W badaniu CMR odnotowano 5 guzów. Wszystkie guzy były zdiagnozowane przypadkowo w pierwszym badaniu CMR, a leczenie pacjentów zostało następnie zmienione.Zmiany pozakardiologiczne stwierdzone w badaniach CMR są częstym zjawiskiem (ok. 29,2%). Radiolodzy i kardiolodzy powinni wiedzieć o ważnych zmianach pozakardiologicznych, które mogą wymagać podjęcia dodatkowej diagnostyki lub leczenia.
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- 2018
49. Cardiac magnetic resonance based deformation imaging: role of feature tracking in athletes with suspected arrhythmogenic right ventricular cardiomyopathy
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Béla Merkely, Zsófia Dohy, László Gellér, Andreas Müssigbrodt, Orsolya Kiss, Csilla Czimbalmos, Ibolya Csecs, Attila Tóth, Ferenc Imre Suhai, and Hajnalka Vágó
- Subjects
Adult ,Male ,medicine.medical_specialty ,Heart Ventricles ,Magnetic Resonance Imaging, Cine ,030204 cardiovascular system & hematology ,Athlete’s heart ,Right ventricular cardiomyopathy ,Ventricular Function, Left ,030218 nuclear medicine & medical imaging ,Free wall ,Diagnosis, Differential ,03 medical and health sciences ,0302 clinical medicine ,Cardiac magnetic resonance imaging ,Predictive Value of Tests ,Internal medicine ,Image Interpretation, Computer-Assisted ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Cardiomegaly, Exercise-Induced ,Cardiac imaging ,Arrhythmogenic Right Ventricular Dysplasia ,Original Paper ,Ejection fraction ,medicine.diagnostic_test ,biology ,Ventricular Remodeling ,business.industry ,Athletes ,Reproducibility of Results ,Stroke Volume ,biology.organism_classification ,Myocardial Contraction ,Feature tracking ,Case-Control Studies ,Cardiology ,Ventricular Function, Right ,Female ,Cardiology and Cardiovascular Medicine ,Cardiac magnetic resonance ,business ,Arrhythmogenic right ventricular cardiomyopathy - Abstract
Both, arrhythmogenic right ventricular cardiomyopathy (ARVC) and regular training are associated with right ventricular (RV) remodelling. Cardiac magnetic resonance (CMR) is given an important role in the diagnosis of ARVC in current task force criteria (TFC), however, they contain no cut-off values for athletes. We aimed to confirm the added value of feature tracking and to provide new cut-off values to differentiate between ARVC and athlete’s heart. Healthy athletes with training of minimal 15 h/week (n = 34), patients with definite ARVC (n = 34) and highly trained athletes with ARVC (n = 8) were examined by CMR. Left and right ventricular volumes and masses were determined. Global right and left ventricular, and regional strain analysis for the RV free wall was performed using feature tracking on balanced steady-state free precession cine images. 94% of healthy athletes showed RV dilatation of the proposed TFC, 14.7% showed RV ejection fraction (RVEF) between 45–50%, none of them had RVEF − 25.6 and > − 1.4, respectively) in all athletes with ARVC were the strain and strain rate of the midventricular RV free wall. Establishing RVEF and RV strain analysis provides an important tool to distinguish ARVC from athlete’s heart. CMR based regional strain and strain rate values may help to identify ARVC even in highly trained athletes with preserved RVEF.
- Published
- 2018
50. Native cardiac magnetic resonance T1 mapping and cardiac mechanics as assessed by speckle tracking echocardiography in patients with beta-thalassaemia major
- Author
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Wing-Shan See, Edwina Kam-fung So, Gloria Yu-Yan Hwang, Leanne Chin, Lawrence Ip, Wendy Wai-man Lam, Shau-yin Ha, and Yiu-fai Cheung
- Subjects
Original Paper ,Cardiac mechanics ,RC666-701 ,cardiovascular system ,Diseases of the circulatory (Cardiovascular) system ,Thalassaemia major ,T1 mapping ,Myocardial strain ,Cardiology and Cardiovascular Medicine ,Cardiac magnetic resonance imaging - Abstract
Background: We hypothesize that cardiac magnetic resonance (CMR) native T1 is associated with myocardial deformation in thalassaemia patients. The present study aimed to compare CMR native T1 values to conventional T2* values in patients with beta-thalassaemia and to explore relationships between these CMR parameters of myocardial iron overload and left ventricular (LV) and left atrial (LA) myocardial deformation. Methods: Thirty-four (16 males) patients aged 35.5 ± 9.2 years were studied. Myocardial T2* and T1 mapping were performed to assess the cardiac iron overload, while two-dimensional speckle-tracking echocardiography was performed in determine LV and LA myocardial deformation. Results: T2* was 36.4 ± 8.7 ms with 3 patients having myocardial iron load (T2*
- Published
- 2022
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