1. Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis
- Author
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Vito Trinchieri, Luciana Mosca, Stefania Macchia, Paola Mastromarino, C. Midulla, Marzia Perluigi, and L. Meggiorini
- Subjects
Adult ,lactobacilli ,Microbiology (medical) ,medicine.medical_specialty ,Placebo ,Gastroenterology ,Statistics, Nonparametric ,law.invention ,Vaginal disease ,Randomized controlled trial ,Double-Blind Method ,law ,Internal medicine ,medicine ,Humans ,vaginal polyamines ,vaginal microbiota ,Vaginal flora ,business.industry ,Biogenic Polyamines ,probiotics ,bacterial vaginosis ,General Medicine ,Vaginosis, Bacterial ,Bacterial vaginosis ,medicine.disease ,Surgery ,Lactobacillus ,medicine.anatomical_structure ,Gram staining ,Infectious Diseases ,Vagina ,Vaginal Creams, Foams, and Jellies ,Intravaginal administration ,Female ,business - Abstract
The purpose of this study was to determine the effectiveness of Lactobacillus-containing vaginal tablets in the treatment of bacterial vaginosis (BV) and in the restoration of a healthy vaginal flora. Thirty-nine women with BV were enrolled in a double-blind, placebo-controlled clinical trial. Patients received either one Lactobacillus-containing tablet or placebo daily for 7 days. Clinical criteria, vaginal Gram stain scores and symptoms were compared with those at the initial visit and those at completion of therapy and 2 weeks later. After completion of therapy, all of the patients in the Lactobacillus-treated group (n = 18) were free of BV, showing a normal (83%) or intermediate (17%) vaginal flora, as compared with only two patients free of BV with intermediate flora (12%) from among the 16 placebo-treated women (p
- Published
- 2009
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