16 results on '"S. Harar"'
Search Results
2. Clinical course of IPF in Italian patients during 12 months of observation: results from the FIBRONET observational study
- Author
-
V. Poletti, C. Vancheri, C. Albera, S. Harari, A. Pesci, R. R. Metella, B. Campolo, G. Crespi, S. Rizzoli, and the FIBRONET study group
- Subjects
Idiopathic pulmonary fibrosis ,Real-world ,Observational ,Italy ,Antifibrotic therapy ,Nintedanib ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background FIBRONET was an observational, multicentre, prospective cohort study investigating the baseline characteristics, clinical course of disease and use of antifibrotic treatment in Italian patients with idiopathic pulmonary fibrosis (IPF). Methods Patients aged ≥ 40 years diagnosed with IPF within the previous 3 months at 20 Italian centres were consecutively enrolled and followed up for 12 months, with evaluations at 3, 6, 9 and 12 months. The primary objective was to describe the clinical course of IPF over 12 months of follow-up, including changes in lung function measured by % predicted forced vital capacity (FVC% predicted). Results 209 patients (82.3% male, mean age 69.54 ± 7.43 years) were enrolled. Mean FVC% predicted was relatively preserved at baseline (80.01%). The mean time between IPF diagnosis and initiation of antifibrotic therapy was 6.38 weeks; 72.3% of patients received antifibrotic therapy within the first 3 months of follow-up, and 83.9% within 12 months of follow-up. Mean FVC% predicted was 80.0% at baseline and 82.2% at 12 months, and 47.4% of patients remained stable (i.e. had no disease progression) in terms of FVC% predicted during the study. Conclusions FIBRONET is the first prospective, real-life, observational study of patients with IPF in Italy. The short time between diagnosis and initiation of antifibrotic therapy, and the stable lung function between baseline and 12 months, suggest that early diagnosis and prompt initiation of antifibrotic therapy may preserve lung function in patients with IPF. Trial registration: NCT02803580
- Published
- 2021
- Full Text
- View/download PDF
3. Management of Globus Pharyngeus
- Author
-
Deborah Claire Sylvester, S. Kortequee, R. S. Harar, P. D. Karkos, S. Sood, Neeraj Sethi, Wolfgang Issing, and H. Atkinson
- Subjects
medicine.medical_specialty ,endocrine system ,business.industry ,musculoskeletal, neural, and ocular physiology ,lcsh:Surgery ,Review Article ,lcsh:RD1-811 ,lcsh:Otorhinolaryngology ,lcsh:RF1-547 ,nervous system diseases ,stomatognathic diseases ,Laryngeal injury ,nervous system ,medicine ,Intensive care medicine ,business ,Rigid oesophagoscopy - Abstract
Globus pharyngeus is a common ENT condition. This paper reviews the current evidence on globus and gives a rational guide to the management of patients with globus. The aetiology of globus is still unclear though most ENT surgeons believe that reflux whether acidic or not plays a significant role. Though proton pump inhibitors are used extensively in practice, there is little evidence to support their efficacy. Most patients with globus can be discharged after simple office investigations. The role of pepsin-induced laryngeal injury is an exciting concept that needs further study. Given the benign nature of globus pharyngeus, in most cases, reassurance rather than treatment or extensive investigation with rigid oesophagoscopy or contrast swallows is all that is needed. We need more research into the aetiology of globus.
- Published
- 2013
4. Complex fragment emission from the 3He+natAg system between 0.48 and 3.6 GeV
- Author
-
E. C. Pollacco, R. Planeta, Sherry Yennello, E. Hourani, R. Legrain, R. Dayras, D. E. Fields, V. E. Viola, C. Volant, S. Harar, Y. Cassagnou, and K. Kwiatkowski
- Subjects
Physics ,Nuclear and High Energy Physics ,Reaction mechanism ,Fragment (computer graphics) ,Nuclear Theory ,Charge (physics) ,Kinetic energy ,Spectral line ,Nuclear physics ,Exponent ,Coulomb ,Atomic physics ,Nuclear Experiment ,Order of magnitude - Abstract
The emission of complex fragments (3⩽ Z ≲12) from reactions of 3 He with nat Ag has been studied at bombarding energies of E = 480, 900, 1800, 2700 and 3600 MeV. Between 900 and 1800 MeV slopes of the fragment kinetic energy spectra at backward angles undergo a change in character, becoming much flatter; in addition, the Coulomb peak is found to broaden significantly and shift to lower energies. Power-law fits to the fragment charge distributions result in decreasing values of the exponent τ up to a bombarding energy of 1800 MeV; at this value and beyond, a constant value of τ =2.1±0.1 is observed. Elemental cross sections at the highest energy are found to increase by approximately two orders of magnitude relative to data near 100 MeV. The data suggest a change in reaction mechanism between incident energies of 900 and 1800 MeV.
- Published
- 1990
- Full Text
- View/download PDF
5. HEAVY-IONS DETECTION BY USING BAF2 CRYSTALS COUPLED TO THIN PLASTIC SCINTILLATOR
- Author
-
A. Foti, C. Volant, R. Barth, E. C. Pollacco, B. Berthier, G. Lanzano, E. De Filippo, V. Lips, A. Cunsolo, C. Mazur, S. Harar, R. Legrain, Angelo Pagano, Y. Cassagnou, R. Dayras, S. Urso, Sl. Cavallaro, J.L. Charvet, E. Berthoumieux, E. Norbeck, Département d'Astrophysique, de physique des Particules, de physique Nucléaire et de l'Instrumentation Associée (DAPNIA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Grand Accélérateur National d'Ions Lourds (GANIL), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Physics ,Coupling ,Nuclear and High Energy Physics ,Isotope ,Fission ,Analytical chemistry ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] ,Scintillator ,Expérience GANIL ,Charged particle ,Ion ,Crystal ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,Atomic physics ,Nuclear Experiment ,Instrumentation - Abstract
By coupling a thin fast NE102A plastic scintillator to a BaF2 crystal, we have been able to detect and identify simultaneously light charged particles and heavy ions from Z = 1 to Z = 18. Time-of-flight information is used to separate Z = 1 isotopes and to distinguish fission fragments from other reaction products.
- Published
- 1992
- Full Text
- View/download PDF
6. Nasal Dilator Strips
- Author
-
Kenyon Gs, Kalan A, Azhar Shaida, and R. P. S. Harar
- Subjects
Otorhinolaryngology ,business.industry ,Dilator ,MEDLINE ,Dentistry ,Medicine ,business - Published
- 2000
- Full Text
- View/download PDF
7. Central collisions in the argon induced fission of thorium in the transition energy regime
- Author
-
F. Saint-Laurent, S. Harar, M. Mostefai, H. Oeschler, Y. Cassagnou, C. Volant, M. Conjeaud, R. Dayras, R. Legrain, and E. C. Pollacco
- Subjects
Physics ,Nuclear and High Energy Physics ,Range (particle radiation) ,Argon ,Fission ,Nuclear Theory ,chemistry.chemical_element ,Thorium ,Nuclear physics ,Cross section (physics) ,chemistry ,Atomic physics ,Nuclear Experiment ,Nucleon ,Saturation (chemistry) ,Excitation - Abstract
Angular correlations between fission fragments induced by an 40Ar bombardment of 232Th targets at four energies, 31, 35, 39 and 44 MeV/u, have been measured as well as the energies, velocities and masses of both fragments. The characteristics of peripheral collisions remain about constant in the range studied, whereas the component attributed to the central collisions which shows a saturation in linear momentum transfer at 180 MeV/c per incident nucleon, has a cross section decreasing with bombarding energy which is correlated to an increase of the excitation energy of the fissioning nuclei.
- Published
- 1985
- Full Text
- View/download PDF
8. Transition from fission to multifragmentation
- Author
-
R. Dayras, H. Oeschler, E. C. Pollacco, E. Kankeleit, Y. Cassagnou, M. Mostefai, G. Klotz-Engmann, C. Volant, M. Conjeaud, S. Harar, and R. Legrain
- Subjects
Physics ,Nuclear physics ,Mass number ,Nuclear and High Energy Physics ,Cold fission ,Fission ,Projectile ,Nuclear Theory ,Thermal ,Atomic physics ,Nuclear Experiment ,Excitation - Abstract
Fragment-fragment correlations have been studied in α -induced reactions at incident energies from 70 to 800 MeV/u on Ag, Ho and Au targets. Even at the highest energy binary thermal fission is observed with excitation energies up to 800–900 MeV. In addition, events with mass number around 30 and relative velocities up to twice the values expected for thermal fission occur and are attributed to multifragmentation. The energy deposit rather than the projectile velocity seems to be parameter governing the appearance of the multifragmentation process which competes strongly with fission for imparted energies beyond 800 MeV.
- Published
- 1987
- Full Text
- View/download PDF
9. Entrance channel versus compound nucleus limitations in the fusion process of 1p and 2s-1d shell nuclei
- Author
-
J.P. Wieleczko, S. Harar, F. Saint-Laurent, and M. Conjeaud
- Subjects
Physics ,Nuclear and High Energy Physics ,Fusion ,Valence (chemistry) ,Nuclear Theory ,Nanotechnology ,Molecular physics ,Entrance channel ,Ion ,medicine.anatomical_structure ,medicine ,Condensed Matter::Strongly Correlated Electrons ,Nuclear Experiment ,Nucleon ,Nucleus - Abstract
The fusion cross sections of systems leading to s-d shell compound nuclei reveal a strong dependence upon the number of valence nucleons of the colliding ions. This striking feature is discussed in terms of entrance channel and compound nucleus effects.
- Published
- 1980
- Full Text
- View/download PDF
10. EVOLUTION OF THE FUSION LIKE PROCESS AROUND THE FERMI ENERGY
- Author
-
B. Chambon, C. Morand, R. Dayras, R. Legrain, A. Douchy, D. Drain, A. Giorni, E. C. Pollacco, M. Conjeaud, C. Volant, Y. Cassagnou, Brigitte Cheynis, J. Gomez del Campo, J.B. Viano, S. Harar, J. Alarja, Département de Physique Nucléaire (ex SPhN) (DPHN), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
- Subjects
Physics ,Nuclear reaction ,Reaction mechanism ,Fusion ,Projectile ,Nuclear Theory ,Fermi level ,General Engineering ,Fermi energy ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] ,7. Clean energy ,Chemical kinetics ,symbols.namesake ,[PHYS.HIST]Physics [physics]/Physics archives ,Mass transfer ,symbols ,Atomic physics ,Nuclear Experiment - Abstract
The study of evaporation residue from the Ne + Ag system shows that there is qualitative change in the reaction mechanism in the Fermi energy domain. At 20 MeV/u the projectile is mostly absobered by the target, while at 30-37 MeV/u a continious range of mass transfer with a large transverse momentum is observed.
- Published
- 1986
- Full Text
- View/download PDF
11. Formation and decay of hot nuclei
- Author
-
E. C. Pollacco, Y. Cassagnou, C. Volant, M. Mostefai, R. Dayras, M. Conjeaud, R. Legrain, G. Klotz-Engmann, S. Harar, and H. Oeschler
- Subjects
Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Angular correlation ,Fission ,Projectile ,Nuclear Theory ,General Engineering ,Atomic physics ,Nuclear Experiment ,Excitation ,Entrance channel - Abstract
Formation and decay properties of composite-like nuclei produced by 58 Ni projectiles bombarding 232 Th target nuclei are investigated at different energies by means of fission fragment angular correlation measurements. Experimental results are compared to the excition model and excitation energies in the fissioning nuclei are deduced. By comparing the present data with the results on other systems, the influences of entrance channel conditions and composite-like nuclei temperatures are discussed to explain the evolution of the high linear momentum transfer region. The coexistence of both massive transfer mmechanism and head-on collisions followed by preequilibrium is suggested.
- Published
- 1987
- Full Text
- View/download PDF
12. A 69-year-old female with multiple, bilateral pulmonary nodules
- Author
-
A. Caminati, A. Cavazza, M.R. Mirenda, and S. Harari
- Subjects
Diseases of the respiratory system ,RC705-779 - Published
- 2011
13. Lymphangioleiomyomatosis: what do we know and what are we looking for?
- Author
-
O. Torre, S. Harari, and J. Moss
- Subjects
LAM cells ,lymphangioleiomyomatosis ,tuberous sclerosis complex ,Diseases of the respiratory system ,RC705-779 - Abstract
Lymphangioleiomyomatosis (LAM) is a rare disease characterised by proliferation of abnormal smooth muscle-like cells (LAM cells) leading to progressive cystic destruction of the lung, lymphatic abnormalities and abdominal tumours. It affects predominantly females and can occur sporadically or in patients with tuberous sclerosis complex. This review describes the recent progress in our understanding of the molecular pathogenesis of the disease and LAM cell biology. It also summarises current therapeutic approaches and the most promising areas of research for future therapeutic strategies.
- Published
- 2011
14. Update on diffuse parenchymal lung disease
- Author
-
S. Harari and A. Caminati
- Subjects
Diseases of the respiratory system ,RC705-779 - Published
- 2010
15. High momentum and energy transfer induced by 1760 MeV $^{40}$Ar on $^{197}$Au and $^{232}$Th targets
- Author
-
S. Harar, R. Legrain, R. Dayras, F. Saint-Laurent, M. Conjeaud, E. C. Pollacco, C. Volant, H. Oeschler, Y. Cassagnou, M.S. Nguyen, Grand Accélérateur National d'Ions Lourds (GANIL), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Physics ,Nuclear and High Energy Physics ,Fission ,Energy transfer ,Momentum transfer ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] ,High momentum ,Nuclear physics ,Mass transfer ,Recoil velocity ,Mass spectrum ,Atomic physics ,Nuclear Experiment ,Excitation - Abstract
Expérience GANIL; Angular correlations between fission fragments induced by 1760 MeV 40Ar bombarding 197Au and 232Th targets have been measured. Energies, velocities and masses have been obtained for both fragments. The momentum transfer and energy deposited were deduced from an event-by-event analysis. The recoil velocity and total mass spectra show that mass transfer is still a dominating process. Momentum transfer of at least 6.5 GeV/c and 900 MeV excitation energy are deduced.
- Published
- 1984
- Full Text
- View/download PDF
16. Book review: Drug-induced and Iatrogenic Respiratory Disease
- Author
-
S. Harari
- Subjects
Diseases of the respiratory system ,RC705-779 - Published
- 2011
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.