19 results on '"Peringa, J."'
Search Results
2. Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO)
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Görgec, B., Hansen, I., Kemmerich, G., Syversveen, T., Abu Hilal, M., Belt, E. J. T., Bisschops, R. H. C., Bollen, T. L., Bosscha, K., Burgmans, M. C., Cappendijk, V., de Boer, M. T., D’Hondt, M., Edwin, B., Gielkens, H., Grünhagen, D. J., Gillardin, P., Gobardhan, P. D., Hartgrink, H. H., Horsthuis, K., Kok, N. F. M., Kint, P. A. M., Kruimer, J. W. H., Leclercq, W. K. G., Lips, D. J., Lutin, B., Maas, M., Marsman, H. A., Morone, M., Pennings, J. P., Peringa, J., te Riele, W. W., Vermaas, M., Wicherts, D., Willemssen, F. E. J. A., Zonderhuis, B. M., Bossuyt, P. M. M., Swijnenburg, R. J., Fretland, A., Verhoef, C., Besselink, M. G., Stoker, J., Bnà, C., de Meyere, C., Draaisma, W. A., Gerhards, M. F., Imani, F., Kuhlmann, K. F. D., Liem, M. S. L., Meyer, Y., Surgery, Radiology & Nuclear Medicine, Graduate School, Radiology and Nuclear Medicine, AMS - Rehabilitation & Development, AMS - Sports, Amsterdam Gastroenterology Endocrinology Metabolism, Epidemiology and Data Science, APH - Methodology, APH - Personalized Medicine, CCA - Imaging and biomarkers, CCA - Cancer Treatment and Quality of Life, Radiology and nuclear medicine, Pathology, Obstetrics and gynaecology, CCA - Cancer Treatment and quality of life, AGEM - Re-generation and cancer of the digestive system, and VU University medical center
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Gadolinium DTPA ,Cancer Research ,Colorectal cancer ,Gadoxetic acid ,Contrast Media ,Diagnostic accuracy ,Multimodal Imaging ,Liver MRI ,Study Protocol ,Liver metastases ,Prospective Studies ,FDG-PET ,RC254-282 ,OUTCOMES ,medicine.diagnostic_test ,Minimal clinically important difference ,Liver Neoplasms ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Magnetic Resonance Imaging ,Oncology ,SURVIVAL ,Radiology ,Colorectal Neoplasms ,Life Sciences & Biomedicine ,medicine.drug ,Adult ,medicine.medical_specialty ,STRATEGIES ,HEPATIC RESECTION ,SDG 3 - Good Health and Well-being ,Genetics ,medicine ,Humans ,In patient ,CANCER PATIENTS ,RADIOFREQUENCY ABLATION ,Liver surgery ,RECURRENCE ,Protocol (science) ,Science & Technology ,business.industry ,Abdominal CT scan ,Magnetic resonance imaging ,Diffusion weighted imaging ,PERFORMANCE ,medicine.disease ,Thermal ablation ,Colorectal liver metastases ,CONTRAST-ENHANCED CT ,Tomography, X-Ray Computed ,business ,Diffusion MRI - Abstract
Background Abdominal computed tomography (CT) is the standard imaging method for patients with suspected colorectal liver metastases (CRLM) in the diagnostic workup for surgery or thermal ablation. Diffusion-weighted and gadoxetic-acid-enhanced magnetic resonance imaging (MRI) of the liver is increasingly used to improve the detection rate and characterization of liver lesions. MRI is superior in detection and characterization of CRLM as compared to CT. However, it is unknown how MRI actually impacts patient management. The primary aim of the CAMINO study is to evaluate whether MRI has sufficient clinical added value to be routinely added to CT in the staging of CRLM. The secondary objective is to identify subgroups who benefit the most from additional MRI. Methods In this international multicentre prospective incremental diagnostic accuracy study, 298 patients with primary or recurrent CRLM scheduled for curative liver resection or thermal ablation based on CT staging will be enrolled from 17 centres across the Netherlands, Belgium, Norway, and Italy. All study participants will undergo CT and diffusion-weighted and gadoxetic-acid enhanced MRI prior to local therapy. The local multidisciplinary team will provide two local therapy plans: first, based on CT-staging and second, based on both CT and MRI. The primary outcome measure is the proportion of clinically significant CRLM (CS-CRLM) detected by MRI not visible on CT. CS-CRLM are defined as liver lesions leading to a change in local therapeutical management. If MRI detects new CRLM in segments which would have been resected in the original operative plan, these are not considered CS-CRLM. It is hypothesized that MRI will lead to the detection of CS-CRLM in ≥10% of patients which is considered the minimal clinically important difference. Furthermore, a prediction model will be developed using multivariable logistic regression modelling to evaluate the predictive value of patient, tumor and procedural variables on finding CS-CRLM on MRI. Discussion The CAMINO study will clarify the clinical added value of MRI to CT in patients with CRLM scheduled for local therapy. This study will provide the evidence required for the implementation of additional MRI in the routine work-up of patients with primary and recurrent CRLM for local therapy. Trial registration The CAMINO study was registered in the Netherlands National Trial Register under number NL8039 on September 20th 2019.
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- 2021
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3. Additional file 1 of Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study
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Görgec, B., Hansen, I., Kemmerich, G., Syversveen, T., Abu Hilal, M., Belt, E. J. T., Bisschops, R. H. C., Bollen, T. L., Bosscha, K., Burgmans, M. C., Cappendijk, V., De Boer, M. T., D’Hondt, M., Edwin, B., Gielkens, H., Grünhagen, D. J., Gillardin, P., Gobardhan, P. D., Hartgrink, H. H., Horsthuis, K., Kok, N. F. M., Kint, P. A. M., Kruimer, J. W. H., Leclercq, W. K. G., Lips, D. J., Lutin, B., Maas, M., Marsman, H. A., Morone, M., Pennings, J. P., Peringa, J., Te Riele, W. W., Vermaas, M., Wicherts, D., Willemssen, F. E. J. A., Zonderhuis, B. M., Bossuyt, P. M. M., Swijnenburg, R. J., Fretland, Å. A., Verhoef, C., Besselink, M. G., and Stoker, J.
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Additional file 1. SPIRIT checklist
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- 2021
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4. Additional file 2 of Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study
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Görgec, B., Hansen, I., Kemmerich, G., Syversveen, T., Abu Hilal, M., Belt, E. J. T., Bisschops, R. H. C., Bollen, T. L., Bosscha, K., Burgmans, M. C., Cappendijk, V., De Boer, M. T., D’Hondt, M., Edwin, B., Gielkens, H., Grünhagen, D. J., Gillardin, P., Gobardhan, P. D., Hartgrink, H. H., Horsthuis, K., Kok, N. F. M., Kint, P. A. M., Kruimer, J. W. H., Leclercq, W. K. G., Lips, D. J., Lutin, B., Maas, M., Marsman, H. A., Morone, M., Pennings, J. P., Peringa, J., Te Riele, W. W., Vermaas, M., Wicherts, D., Willemssen, F. E. J. A., Zonderhuis, B. M., Bossuyt, P. M. M., Swijnenburg, R. J., Fretland, Å. A., Verhoef, C., Besselink, M. G., and Stoker, J.
- Abstract
Additional file 2. Imaging Protocols of The Radiological Society of the Netherlands
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- 2021
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- View/download PDF
5. Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO):study protocol for an international multicentre prospective diagnostic accuracy study
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Görgec, B, Hansen, I, Kemmerich, G, Syversveen, T, Abu Hilal, M, Belt, E J T, Bisschops, R H C, Bollen, T L, Bosscha, K, Burgmans, M C, Cappendijk, V, De Boer, M T, D'Hondt, M, Edwin, B, Gielkens, H, Grünhagen, D J, Gillardin, P, Gobardhan, P D, Hartgrink, H H, Horsthuis, K, Kok, N F M, Kint, P A M, Kruimer, J W H, Leclercq, W K G, Lips, D J, Lutin, B, Maas, M, Marsman, H A, Morone, M, Pennings, J P, Peringa, J, Te Riele, W W, Vermaas, M, Wicherts, D, Willemssen, F E J A, Zonderhuis, B M, Bossuyt, P M M, Swijnenburg, R J, Fretland, Å A, Verhoef, C, Besselink, M G, Stoker, J, Görgec, B, Hansen, I, Kemmerich, G, Syversveen, T, Abu Hilal, M, Belt, E J T, Bisschops, R H C, Bollen, T L, Bosscha, K, Burgmans, M C, Cappendijk, V, De Boer, M T, D'Hondt, M, Edwin, B, Gielkens, H, Grünhagen, D J, Gillardin, P, Gobardhan, P D, Hartgrink, H H, Horsthuis, K, Kok, N F M, Kint, P A M, Kruimer, J W H, Leclercq, W K G, Lips, D J, Lutin, B, Maas, M, Marsman, H A, Morone, M, Pennings, J P, Peringa, J, Te Riele, W W, Vermaas, M, Wicherts, D, Willemssen, F E J A, Zonderhuis, B M, Bossuyt, P M M, Swijnenburg, R J, Fretland, Å A, Verhoef, C, Besselink, M G, and Stoker, J
- Abstract
BACKGROUND: Abdominal computed tomography (CT) is the standard imaging method for patients with suspected colorectal liver metastases (CRLM) in the diagnostic workup for surgery or thermal ablation. Diffusion-weighted and gadoxetic-acid-enhanced magnetic resonance imaging (MRI) of the liver is increasingly used to improve the detection rate and characterization of liver lesions. MRI is superior in detection and characterization of CRLM as compared to CT. However, it is unknown how MRI actually impacts patient management. The primary aim of the CAMINO study is to evaluate whether MRI has sufficient clinical added value to be routinely added to CT in the staging of CRLM. The secondary objective is to identify subgroups who benefit the most from additional MRI.METHODS: In this international multicentre prospective incremental diagnostic accuracy study, 298 patients with primary or recurrent CRLM scheduled for curative liver resection or thermal ablation based on CT staging will be enrolled from 17 centres across the Netherlands, Belgium, Norway, and Italy. All study participants will undergo CT and diffusion-weighted and gadoxetic-acid enhanced MRI prior to local therapy. The local multidisciplinary team will provide two local therapy plans: first, based on CT-staging and second, based on both CT and MRI. The primary outcome measure is the proportion of clinically significant CRLM (CS-CRLM) detected by MRI not visible on CT. CS-CRLM are defined as liver lesions leading to a change in local therapeutical management. If MRI detects new CRLM in segments which would have been resected in the original operative plan, these are not considered CS-CRLM. It is hypothesized that MRI will lead to the detection of CS-CRLM in ≥10% of patients which is considered the minimal clinically important difference. Furthermore, a prediction model will be developed using multivariable logistic regression modelling to evaluate the predictive value of patient, tumor and procedural va
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- 2021
6. Colorectal liver metastases:Surgery versus thermal ablation (COLLISION) - a phase III single-blind prospective randomized controlled trial
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Puijk, RS, Ruarus, AH, Vroomen, LGPH, van Tilborg, AA, Scheffer, HJ, Nielsen, K, Jong, MC, Vries, JJ, Zonderhuis, BM, Eker, HH, Kazemier, G, Verheul, H, van der Meijs, BB, Dam, L, Sorgedrager, N, Coupé, VMH, van den Tol, PM, Meijerink, MR, Prevoo, W, Kok, N, Diederik, AL, Spaargaren, GJ, Sietses, C, van Heek, TNT, Serafino, G, Futterer, JJ, van den Boezem, PB, Stommel, M, de Wilt, H, Arntz, M, Jenniskens, S, Besselink, M, van Delden, OM, Gulik, TM, Tanis, PJ, van Lienden, KP, Burgmans, M C, Swijnenburg, RJ, van Erkel, AR, Hartgrink, HH, Peringa, J, Marsman, H, Jacobs, PC, Gerhards, MF, van der Leij, C, Brans, R, Coolsen, MME, Dejong, KCHC, Dam, R, Solouki, AM, Dol, JA, Vink, TWF, Manusama, ER, Patijn, GA, Nieuwenhuijs, VB, Meijer, MAJ, Torrenga, H, Sonneveld, EDJA, de Waard, JWD, Joosten, JJ, Verhoef, Kees, Moelker, Adriaan, Grunhagen, DJ, Groot Koerkamp, B, Hagendoorn, J, Molenaar, I, Bruijnen, RCG, van Nieuwkerk, KCMJ, van de Ven, P, Bakker, J, Leenders, MWH, Hellingman, T, van Grieken, N, Nieuwenhuizen, S, Geboers, B, Kuijk, C, de Wind, A, Anema, H, Breen, DJ, Aldrighetti, L, Cobelli, FD, Ratti, F, Marra, P, Albrecht, T, Muller, PD, Radiology and nuclear medicine, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and quality of life, Surgery, Medical oncology, Epidemiology and Data Science, APH - Methodology, ACS - Heart failure & arrhythmias, Pathology, Other Research, Public and occupational health, APH - Societal Participation & Health, Radiology & Nuclear Medicine, Puijk, Robbert S, Ruarus, Alette H, Vroomen, Laurien GPH, van Tilborg, Aukje AJM, Scheffer, Hester J, Nielsen, Karin, de Jong, Marcus C, de Vries, Jan JJ, Zonderhuis, Babs M, Eker, Hasan H, Kazemier, Geert, Verheul, Henk, van der Meijs, Bram B, van Dam, Laura, Sorgedrager, Natasha, Coupé, Veerle MH, van den Tol, Petrousjka MP, Meijerink, Martijn R, on behalf of COLLISION Trial, Group, Aldrighetti, Luca, De Cobelli, Francesco, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA - Imaging and biomarkers, CCA - Cancer Treatment and Quality of Life, ACS - Amsterdam Cardiovascular Sciences, Radiology and Nuclear Medicine, AGEM - Endocrinology, metabolism and nutrition, AGEM - Digestive immunity, and Graduate School
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Liver metastase ,Male ,Target lesion ,Cancer Research ,Colorectal cancer ,Radiofrequency ablation ,Colorectal Neoplasm ,030230 surgery ,law.invention ,Study Protocol ,Liver metastases ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Randomized controlled trial ,Quality of life ,law ,Quality-Adjusted Life Year ,Clinical endpoint ,Medicine ,Colorectal liver metastases (CRLM) ,Liver Neoplasms ,Microwave ablation ,Microwave ablation (MWA) ,Middle Aged ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Treatment Outcome ,Liver ,Oncology ,Liver Neoplasm ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,030220 oncology & carcinogenesis ,Catheter Ablation ,Female ,Quality-Adjusted Life Years ,Colorectal Neoplasms ,Human ,Adult ,medicine.medical_specialty ,lcsh:RC254-282 ,Disease-Free Survival ,03 medical and health sciences ,Genetic ,Genetics ,Humans ,Hepatectomy ,Liver surgery ,Aged ,business.industry ,Radiofrequency ablation (RFA) ,Other Research Radboud Institute for Health Sciences [Radboudumc 0] ,medicine.disease ,Hepatic resection ,Thermal ablation ,Surgery ,Clinical trial ,business - Abstract
Contains fulltext : 195648.pdf (Publisher’s version ) (Open Access) BACKGROUND: Radiofrequency ablation (RFA) and microwave ablation (MWA) are widely accepted techniques to eliminate small unresectable colorectal liver metastases (CRLM). Although previous studies labelled thermal ablation inferior to surgical resection, the apparent selection bias when comparing patients with unresectable disease to surgical candidates, the superior safety profile, and the competitive overall survival results for the more recent reports mandate the setup of a randomized controlled trial. The objective of the COLLISION trial is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable CRLM and no extrahepatic disease. METHODS: In this two-arm, single-blind multi-center phase-III clinical trial, six hundred and eighteen patients with at least one CRLM (
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- 2018
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7. Individual‐patient meta‐analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm
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Sweeting, M. J., Balm, R., Desgranges, P., Ulug, P., Powell, J. T., Koelemay, M. J. W., Idu, M. M., Kox, C., Legemate, D. A., Huisman, L. C., Willems, M. C. M., Reekers, J. A., van Delden, O. M., van Lienden, K. P., Hoornweg, L. L., Reimerink, J. J., van Beek, S. C., Vahl, A. C., Leijdekkers, V. J., Bosma, J., Montauban van Swijndregt, A. D., de Vries, C., van der Hulst, V. P. M., Peringa, J., Blomjous, J. G. A. M., Visser, M. J. T., van der Heijden, F. H. W. M., Wisselink, W., Hoksbergen, A. W. J., Blankensteijn, J. D., Visser, M. T. J., Coveliers, H. M. E., Nederhoed, J. H., van den Berg, F. G., van der Meijs, B. B., van den Oever, M. L. P., Lely, R. J., Meijerink, M. R., Voorwinde, A., Ultee, J. M., van Nieuwenhuizen, R. C., Dwars, B. J., Nagy, T. O. M., Tolenaar, P., Wiersema, A. M., Lawson, J. A., van Aken, P. J., Stigter, A. A., van den Broek, T. A. A., Vos, G. A., Mulder, W., Strating, R. P., Nio, D., Akkersdijk, G. J. M., van der Elst, A., Exter, P.van, Becquemin, J.‐P., Allaire, E., Cochennec, F., Marzelle, J., Louis, N., Schneider, J., Majewski, M., Castier, Y., Leseche, G., Francis, F., Steinmetz, E., Berne, J.‐P., Favier, C., Haulon, S., Koussa, M., Azzaoui, R., Piervito, D., Alimi, Y., Boufi, M., Hartung, O., Cerquetta, P., Amabile, P., Piquet, P., Penard, J., Demasi, M., Alric, P., Canaud, L., Berthet, J.‐P., Julia, P., Fabiani, J.‐N., Alsac, J. M., Gouny, P., Badra, A., Braesco, J., Favre, J.‐P., Albertini, J.‐N., Martinez, R., Hassen‐Khodja, R., Batt, M., Jean, E., Sosa, M., Declemy, S., Destrieux‐Garnier, L., Lermusiaux, P., Feugier, P., Ashleigh, R., Gomes, M., Greenhalgh, R. M., Grieve, R., Hinchliffe, R., Sweeting, M., Thompson, M. M., Thompson, S. G., Cheshire, N. J., Boyle, J. R., Serracino‐Inglott, F., Smyth, J. V., Hinchliffe, R. J., Bell, R., Wilson, N., Bown, M., Dennis, M., Davis, M., Howell, S., Wyatt, M. G., Valenti, D., Bachoo, P., Walker, P., MacSweeney, S., Davies, J. N., Rittoo, D., Parvin, S. D., Yusuf, W., Nice, C., Chetter, I., Howard, A., Chong, P., Bhat, R., McLain, D., Gordon, A., Lane, I., Hobbs, S., Pillay, W., Rowlands, T., El‐Tahir, A., Asquith, J., Cavanagh, S., Dubois, L., Forbes, T. L., ACS - Amsterdam Cardiovascular Sciences, Surgery, 02 Surgical specialisms, Radiology and Nuclear Medicine, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, Other departments, and Oral and Maxillofacial Surgery
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medicine.medical_specialty ,Aortic Rupture ,Population ,law.invention ,Aneurysm ,Randomized controlled trial ,law ,medicine ,Humans ,cardiovascular diseases ,education ,Randomized Controlled Trials as Topic ,education.field_of_study ,business.industry ,Mortality rate ,Hazard ratio ,Endovascular Procedures ,Odds ratio ,Original Articles ,medicine.disease ,Abdominal aortic aneurysm ,Surgery ,Treatment Outcome ,Meta-analysis ,cardiovascular system ,Original Article ,business ,Vascular Surgical Procedures ,Aortic Aneurysm, Abdominal - Abstract
Background The benefits of endovascular repair of ruptured abdominal aortic aneurysm remain controversial, without any strong evidence about advantages in specific subgroups. Methods An individual‐patient data meta‐analysis of three recent randomized trials of endovascular versus open repair of abdominal aortic aneurysm was conducted according to a prespecified analysis plan, reporting on results to 90 days after the index event. Results The trials included a total of 836 patients. The mortality rate across the three trials was 31·3 per cent for patients randomized to endovascular repair/strategy and 34·0 per cent for those randomized to open repair at 30 days (pooled odds ratio 0·88, 95 per cent c.i. 0·66 to 1·18), and 34·3 and 38·0 per cent respectively at 90 days (pooled odds ratio 0·85, 0·64 to 1·13). There was no evidence of significant heterogeneity in the odds ratios between trials. Mean(s.d.) aneurysm diameter was 8·2(1·9) cm and the overall in‐hospital mortality rate was 34·8 per cent. There was no significant effect modification with age or Hardman index, but there was indication of an early benefit from an endovascular strategy for women. Discharge from the primary hospital was faster after endovascular repair (hazard ratio 1·24, 95 per cent c.i. 1·04 to 1·47). For open repair, 30‐day mortality diminished with increasing aneurysm neck length (adjusted odds ratio 0·69 (95 per cent c.i. 0·53 to 0·89) per 15 mm), but aortic diameter was not associated with mortality for either type of repair. Conclusion Survival to 90 days following an endovascular or open repair strategy is similar for all patients and for the restricted population anatomically suitable for endovascular repair. Women may benefit more from an endovascular strategy than men and patients are, on average, discharged sooner after endovascular repair., Strong evidence of equivalence
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- 2015
8. Colorectal liver metastases: Surgery versus thermal ablation (COLLISION) - a phase III single-blind prospective randomized controlled trial
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Puijk, R.S. (Robbert S.), Ruarus, A.H. (Alette H.), Vroomen, L.G.P.H. (Laurien G.P.H.), van Tilborg, A.A.J.M. (Aukje A.J.M.), Scheffer, H.J. (Hester J.), Nielsen, K. (Karin), Jong, M.C. (Marcus) de, Vries, J.J.J. (Jan) de, Zonderhuis, B.M. (Babs M.), Eker, H.H. (Hasan), Kazemier, G. (Geert), Verheul, H.M.W. (Henk), van der Meijs, B.B. (Bram B.), van Dam, L. (Laura), Sorgedrager, N. (Natasha), Coupé, V.M.H. (Veerle), van den Tol, P.M.P. (Petrousjka M.P.), Meijerink, M.R. (Martijn R.), Prevoo, Y.F.D.M. (Yves), Kok, N. (Niels), Diederik, A.L. (Arjen L.), Spaargaren, G.J. (Gert Jan), Sietses, C. (C.), van Heek, T.N. (Tjarda N.), Serafino, G. (GianPiero), Fütterer, J. (Jurgen), Boezem, P.B. van den, Stommel, M. (Martijn), Wilt, H. (Hans) de, Arntz, M. (Mark), Jenniskens, S. (Sjoerd), Besselink, M. (Mark), Delden, O.M. (Otto) van, Gulik, T.M. (Thomas) van, Tanis, P.J. (Pieter), Lienden, K.P. (Krijn) van, Burgmans, M.C. (Mark C.), Swijnenburg, R.-J. (Rutger-Jan), Erkel, A.R. (A.) van, Hartgrink, H.H. (H.), Peringa, J. (Jan), Marsman, H.A. (H. A.), Jacobs, P.C.A. (Peter C.A.), Gerhards, M.F. (Michael), Leij, C. (Christiaan) van der, Brans, R. (Rutger), Coolsen, M.M.E. (Marielle M.E.), Dejong, K. (Kees), Dam, R. (Ronald) van, Solouki, A.M. (Abbas Millad), Dol, J.A. (Johan A.), Vink, T.W.F. (Ted W.F.), Manusama, E.R. (Eric), Patijn, G.A. (Gijs A.), Nieuwenhuijs, V.B. (Vincent), Meijer, M.A.J. (Mark A.J.), Torrenga, H. (Hans), Sonneveld, E.D.J.A. (Eric), de Waard, J.-W.W.D. (Jan-Willem W.D.), Joosten, J.J. (Joris), Verhoef, C. (Cees), Moelker, A. (Adriaan), Grunhagen, D.J. (Dirk Jan), Groot Koerkamp, B. (Bas), Hagendoorn, J. (Jeroen), Quintus Molenaar, I. (I.), Bruijnen, R.C.G. (Rutger C.G.), van Nieuwkerk, K.C.M.J. (Karin C.M.J.), Ven, P.M. (Peter) van de, de Bakker, J. (Jacob), Leenders, M.W.H. (Martijn W.H.), Hellingman, T. (Tessa), Grieken, N.C.T. (Nicole), Nieuwenhuizen, S. (Sanne), Geboers, B. (Bart), Kuijk, C. (Cornelis) van, de Wind, A. (Astrid), Anema, J.R. (Han), Breen, D.J. (David J.), Aldrighetti, L.A. (L.), Cobelli, F.D. (Francesco De), Ratti, F. (Francesca), Marra, P. (Paolo), Albrecht, T. (Thomas), Muller, P.D. (P. D.), Puijk, R.S. (Robbert S.), Ruarus, A.H. (Alette H.), Vroomen, L.G.P.H. (Laurien G.P.H.), van Tilborg, A.A.J.M. (Aukje A.J.M.), Scheffer, H.J. (Hester J.), Nielsen, K. (Karin), Jong, M.C. (Marcus) de, Vries, J.J.J. (Jan) de, Zonderhuis, B.M. (Babs M.), Eker, H.H. (Hasan), Kazemier, G. (Geert), Verheul, H.M.W. (Henk), van der Meijs, B.B. (Bram B.), van Dam, L. (Laura), Sorgedrager, N. (Natasha), Coupé, V.M.H. (Veerle), van den Tol, P.M.P. (Petrousjka M.P.), Meijerink, M.R. (Martijn R.), Prevoo, Y.F.D.M. (Yves), Kok, N. (Niels), Diederik, A.L. (Arjen L.), Spaargaren, G.J. (Gert Jan), Sietses, C. (C.), van Heek, T.N. (Tjarda N.), Serafino, G. (GianPiero), Fütterer, J. (Jurgen), Boezem, P.B. van den, Stommel, M. (Martijn), Wilt, H. (Hans) de, Arntz, M. (Mark), Jenniskens, S. (Sjoerd), Besselink, M. (Mark), Delden, O.M. (Otto) van, Gulik, T.M. (Thomas) van, Tanis, P.J. (Pieter), Lienden, K.P. (Krijn) van, Burgmans, M.C. (Mark C.), Swijnenburg, R.-J. (Rutger-Jan), Erkel, A.R. (A.) van, Hartgrink, H.H. (H.), Peringa, J. (Jan), Marsman, H.A. (H. A.), Jacobs, P.C.A. (Peter C.A.), Gerhards, M.F. (Michael), Leij, C. (Christiaan) van der, Brans, R. (Rutger), Coolsen, M.M.E. (Marielle M.E.), Dejong, K. (Kees), Dam, R. (Ronald) van, Solouki, A.M. (Abbas Millad), Dol, J.A. (Johan A.), Vink, T.W.F. (Ted W.F.), Manusama, E.R. (Eric), Patijn, G.A. (Gijs A.), Nieuwenhuijs, V.B. (Vincent), Meijer, M.A.J. (Mark A.J.), Torrenga, H. (Hans), Sonneveld, E.D.J.A. (Eric), de Waard, J.-W.W.D. (Jan-Willem W.D.), Joosten, J.J. (Joris), Verhoef, C. (Cees), Moelker, A. (Adriaan), Grunhagen, D.J. (Dirk Jan), Groot Koerkamp, B. (Bas), Hagendoorn, J. (Jeroen), Quintus Molenaar, I. (I.), Bruijnen, R.C.G. (Rutger C.G.), van Nieuwkerk, K.C.M.J. (Karin C.M.J.), Ven, P.M. (Peter) van de, de Bakker, J. (Jacob), Leenders, M.W.H. (Martijn W.H.), Hellingman, T. (Tessa), Grieken, N.C.T. (Nicole), Nieuwenhuizen, S. (Sanne), Geboers, B. (Bart), Kuijk, C. (Cornelis) van, de Wind, A. (Astrid), Anema, J.R. (Han), Breen, D.J. (David J.), Aldrighetti, L.A. (L.), Cobelli, F.D. (Francesco De), Ratti, F. (Francesca), Marra, P. (Paolo), Albrecht, T. (Thomas), and Muller, P.D. (P. D.)
- Abstract
Background: Radiofrequency ablation (RFA) and microwave ablation (MWA) are widely accepted techniques to eliminate small unresectable colorectal liver metastases (CRLM). Although previous studies labelled thermal ablation inferior to surgical resection, the apparent selection bias when comparing patients with unresectable disease to surgical candidates, the superior safety profile, and the competitive overall survival results for the more recent reports mandate the setup of a randomized controlled trial. The objective of the COLLISION trial is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable CRLM and no extrahepatic disease. Methods: In this two-arm, single-blind multi-center phase-III clinical trial, six hundred and eighteen patients with at least one CRLM (≤3cm) will be included to undergo either surgical resection or thermal ablation of appointed target lesion(s) (≤3cm). Primary endpoint is OS (overall survival, intention-to-treat analysis). Main secondary endpoints are overall disease-free survival (DFS), time to progression (TTP), time to local progression (TTLP), primary and assisted technique efficacy (PTE, ATE), procedural morbidity and mortality, length of hospital stay, assessment of pain and quality of life (QoL), cost-effectiveness ratio (ICER) and quality-adjusted life years (QALY). Discussion: If thermal ablation proves to be non-inferior in treating lesions ≤3cm, a switch in treatment-method may lead to a reduction of the post-procedural morbidity and mortality, length of hospital stay and incremental costs without compromising
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- 2018
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9. Colorectal liver metastases: Surgery versus thermal ablation (COLLISION) - a phase III single-blind prospective randomized controlled trial
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Puijk, RS, Ruarus, AH, Vroomen, LGPH, van Tilborg, AA, Scheffer, HJ, Nielsen, K, Jong, MC, Vries, JJ, Zonderhuis, BM, Eker, HH, Kazemier, G, Verheul, H, van der Meijs, BB, Dam, L, Sorgedrager, N, Coupé, VMH, van den Tol, PM, Meijerink, MR, Prevoo, W, Kok, N, Diederik, AL, Spaargaren, GJ, Sietses, C, van Heek, TNT, Serafino, G, Futterer, JJ, van den Boezem, PB, Stommel, M, de Wilt, H, Arntz, M, Jenniskens, S, Besselink, M, van Delden, OM, Gulik, TM, Tanis, PJ, van Lienden, KP, Burgmans, M C, Swijnenburg, RJ, van Erkel, AR, Hartgrink, HH, Peringa, J, Marsman, H, Jacobs, PC, Gerhards, MF, van der Leij, C, Brans, R, Coolsen, MME, Dejong, KCHC, Dam, R, Solouki, AM, Dol, JA, Vink, TWF, Manusama, ER, Patijn, GA, Nieuwenhuijs, VB, Meijer, MAJ, Torrenga, H, Sonneveld, EDJA, de Waard, JWD, Joosten, JJ, Verhoef, Kees, Moelker, Adriaan, Grunhagen, DJ, Groot Koerkamp, B, Hagendoorn, J, Molenaar, I, Bruijnen, RCG, van Nieuwkerk, KCMJ, van de Ven, P, Bakker, J, Leenders, MWH, Hellingman, T, van Grieken, N, Nieuwenhuizen, S, Geboers, B, Kuijk, C, de Wind, A, Anema, H, Breen, DJ, Aldrighetti, L, Cobelli, FD, Ratti, F, Marra, P, Albrecht, T, Muller, PD, Puijk, RS, Ruarus, AH, Vroomen, LGPH, van Tilborg, AA, Scheffer, HJ, Nielsen, K, Jong, MC, Vries, JJ, Zonderhuis, BM, Eker, HH, Kazemier, G, Verheul, H, van der Meijs, BB, Dam, L, Sorgedrager, N, Coupé, VMH, van den Tol, PM, Meijerink, MR, Prevoo, W, Kok, N, Diederik, AL, Spaargaren, GJ, Sietses, C, van Heek, TNT, Serafino, G, Futterer, JJ, van den Boezem, PB, Stommel, M, de Wilt, H, Arntz, M, Jenniskens, S, Besselink, M, van Delden, OM, Gulik, TM, Tanis, PJ, van Lienden, KP, Burgmans, M C, Swijnenburg, RJ, van Erkel, AR, Hartgrink, HH, Peringa, J, Marsman, H, Jacobs, PC, Gerhards, MF, van der Leij, C, Brans, R, Coolsen, MME, Dejong, KCHC, Dam, R, Solouki, AM, Dol, JA, Vink, TWF, Manusama, ER, Patijn, GA, Nieuwenhuijs, VB, Meijer, MAJ, Torrenga, H, Sonneveld, EDJA, de Waard, JWD, Joosten, JJ, Verhoef, Kees, Moelker, Adriaan, Grunhagen, DJ, Groot Koerkamp, B, Hagendoorn, J, Molenaar, I, Bruijnen, RCG, van Nieuwkerk, KCMJ, van de Ven, P, Bakker, J, Leenders, MWH, Hellingman, T, van Grieken, N, Nieuwenhuizen, S, Geboers, B, Kuijk, C, de Wind, A, Anema, H, Breen, DJ, Aldrighetti, L, Cobelli, FD, Ratti, F, Marra, P, Albrecht, T, and Muller, PD
- Published
- 2018
10. Cat scratch disease, a rare cause of hypodense liver lesions, lymphadenopathy and a protruding duodenal lesion, caused by Bartonella henselae
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van Ierland-van Leeuwen, M., primary, Peringa, J., additional, Blaauwgeers, H., additional, and van Dam, A., additional
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- 2014
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11. Photo quiz. Bilateral adrenal tumour
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Bisschop, P. H., Peringa, J., Blaauwgeers, J. L. G., Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Movement Sciences, and Cardiology
- Published
- 2003
12. The role of plain radiographs in patients with acute abdominal pain at the ED
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Randen, A. van, Lameris, W., Luitse, J.S., Gorzeman, M., Hesselink, E.J., Dolmans, D.E., Peringa, J., Geloven, A.A. van, Bossuyt, P.M., Stoker, J., Boermeester, M.A., Gooszen, H.G., et al., Randen, A. van, Lameris, W., Luitse, J.S., Gorzeman, M., Hesselink, E.J., Dolmans, D.E., Peringa, J., Geloven, A.A. van, Bossuyt, P.M., Stoker, J., Boermeester, M.A., Gooszen, H.G., and et al.
- Abstract
Item does not contain fulltext, OBJECTIVE: The purpose of this study was to evaluate the added value of plain radiographs on top of clinical assessment in unselected patients presenting with acute abdominal pain at the emergency department (ED). METHODS: In a multicenter prospective trial, patients with abdominal pain more than 2 hours and less than 5 days presented at the ED were evaluated clinically, and a diagnosis was made by the treating physician. Subsequently, all patients underwent supine abdominal and upright chest radiographs, after which the diagnosis was reassessed by the treating physician. A final (reference) diagnosis was assigned by an expert panel. The number of changes in the primary diagnosis, as well as the accuracy of these changes, was calculated. Changes in the level of confidence were evaluated for unchanged diagnoses. RESULTS: Between March 2005 and November 2006, 1021 patients, 55% female, mean age 47 years (range, 19-94 years), were included. In 117 of 1021 patients, the diagnosis changed after plain radiographs, and this change was correct in 39 patients (22% of changed diagnoses and 4% of total study population). Overall, the clinical diagnosis was correct in 502 (49%) patients. The diagnosis after evaluation of the radiographs was correct in 514 (50%) patients, a nonsignificant difference (P = .14). In 65% of patients with unchanged diagnosis before and after plain radiography, the level of confidence of that diagnosis did not change either. CONCLUSION: The added value of plain radiographs is too limited to advocate their routine use in the diagnostic workup of patients with acute abdominal pain, because few diagnoses change and the level of confidence were mostly not affected.
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- 2011
13. Chest computed tomography and alveolar-arterial oxygen gradient as rapid tools to diagnose and triage mildly symptomatic COVID-19 pneumonia patients.
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de Roos MP, Kilsdonk ID, Hekking PW, Peringa J, Dijkstra NG, Kunst PWA, Bresser P, and Reesink HJ
- Abstract
Background: In the coronavirus disease 2019 (COVID-19) pandemic, rapid clinical triage is crucial to determine which patients need hospitalisation. We hypothesised that chest computed tomography (CT) and alveolar-arterial oxygen tension ratio (A-a) gradient may be useful to triage these patients, since they reflect the severity of the pneumonia-associated ventilation/perfusion abnormalities., Methods: A retrospective analysis was performed in 235 consecutive patients suspected for COVID-19. The diagnostic protocol included low-dose chest CT and arterial blood gas analysis. In patients with CT-based COVID-19 pneumonia, the association between "need for hospitalisation" and A-a gradient was investigated by a multivariable logistic regression model. The A-a gradient was tested as a predictor for need for hospitalisation using receiver operating characteristic curve analysis and a logistic regression model., Results: 72 out of 235 patients (mean±sd age 55.5±14.6 years, 40% female) screened by chest CT showed evidence for COVID-19 pneumonia. In these patients, A-a gradient was shown to be a predictor of need for hospitalisation, with an optimal decision level (cut-off) of 36.4 mmHg (95% CI 0.70-0.91, p<0.001). The A-a gradient was shown to be independently associated with need for hospitalisation (OR 1.97 (95% CI 1.23-3.15), p=0.005; A-a gradient per 10 points) from CT severity score (OR 1.13 (95% CI 0.94-1.36), p=0.191), National Early Warning Score (OR 1.19 (95% CI 0.91-1.57), p=0.321) or peripheral oxygen saturation (OR 0.88 (95% CI 0.68-1.14), p=0.345)., Conclusion: Low-dose chest CT and the A-a gradient may serve as rapid and accurate tools to diagnose COVID-19 pneumonia and to select mildly symptomatic patients in need for hospitalisation., Competing Interests: Conflict of interest: M.P. de Roos has nothing to disclose. Conflict of interest: I.D. Kilsdonk has nothing to disclose. Conflict of interest: P-P.W. Hekking has nothing to disclose. Conflict of interest: J. Peringa has nothing to disclose. Conflict of interest: N.G. Dijkstra has nothing to disclose. Conflict of interest: P.W.A. Kunst has nothing to disclose. Conflict of interest: P. Bresser has nothing to disclose . Conflict of interest: H.J. Reesink has nothing to disclose., (Copyright ©The authors 2021.)
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- 2021
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14. Frequency and spectrum of incidental findings when using chest CT as a primary triage tool for COVID-19.
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Kilsdonk ID, de Roos MP, Bresser P, Reesink HJ, and Peringa J
- Abstract
Purpose: To determine the prevalence and spectrum of incidental findings (IFs) identified in patients undergoing chest CT as a primary triage tool for COVID-19., Methods: In this study 232 patients were triaged in our COVID-19 Screening Unit by means of a chest CT (March 25-April 23, 2020). Original radiology reports were evaluated retrospectively for the description of IFs, which were defined as any finding in the report not related to the purpose of the scan. Documented IFs were categorized according to clinical relevance into minor and potentially significant IFs and according to anatomical location into pulmonary, mediastinal, cardiovascular, breast, upper abdominal and skeletal categories. IFs were reported as frequencies and percentages; descriptive statistics were used., Results: In total 197 IFs were detected in 126 patients (54 % of the participants). Patients with IFs were on average older (54.0 years old, SD 16.6) than patients without IFs (44.8 years old, SD 14.6, P < 0.05). In total 60 potentially significant IFs were detected in 53 patients (23 % of the participants). Most often reported were coronary artery calcifications (n = 23, 38 % of total potentially significant IFs/ 10 % of the total study population), suspicious breast nodules (n = 7, 12 % of total potentially significant IFs/ 3% of the total study population) and pulmonary nodules (n = 7, 12 % of total potentially significant IFs/ 3% of the total study population)., Conclusion: A considerable number of IFs were detected by using chest CT as a primary triage tool for COVID-19, of which a substantial percentage (23 %) is potentially clinically relevant., Competing Interests: The authors report no declarations of interest., (© 2021 The Authors.)
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- 2021
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15. Contrast medium at the site of the anastomosis is crucial in detecting anastomotic leakage with CT imaging after colorectal surgery.
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Huiberts AA, Dijksman LM, Boer SA, Krul EJ, Peringa J, and Donkervoort SC
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- Aged, Aged, 80 and over, Anastomosis, Surgical adverse effects, Anastomotic Leak etiology, Colorectal Neoplasms surgery, Female, Humans, Logistic Models, Male, Middle Aged, Observer Variation, Sensitivity and Specificity, Anastomotic Leak diagnostic imaging, Colon surgery, Contrast Media, Rectum surgery, Tomography, X-Ray Computed methods
- Abstract
Purpose: The use of computed tomography (CT) to detect anastomotic leakage (AL) is becoming the standard of care. Accurate detection of AL is crucial. The aim of this study was to define CT criteria that are most predictive for AL., Methods: From January 2006 to December 2012, all consecutive patients who had undergone CT imaging because of clinical suspicion of anastomotic leakage after colorectal surgery were analysed. All CT scans were re-evaluated by two independent abdominal radiologists blinded for clinical outcome. The images were scored with a set of criteria and a conclusion whether or not AL was present was drawn. Each separate criterion was analysed for its value in predicting AL by uni- and multivariable logistic regression, Results: Of 668 patients with colorectal surgery, 108 had undergone CT imaging within 16 days postoperatively. According to our standard of reference, 34 (31%) of the patients had AL. Univariable analysis showed that "fluid near anastomosis" (radiologist 1 (rad 1), p < 0.001; radiologist 2 (rad 2), p < 0.001) and "air near anastomosis" (rad 1, p < 0.001; rad 2, p < 0.001), "air intra-abdominally" (rad 1, p = 0.019; rad 2, p = 0.004) and "contrast leakage" (rad 1, p < 0.001; rad 2, p < 0.001) were associated with AL. Contrast leakage was the only independent predictor for AL in multivariable analysis for both radiologists (rad 1, OR 5.43 (95% CI 1.18-25.02); rad 2, OR 8.51 (95% CI 2.21-32.83))., Conclusion: The only independent variable predicting AL is leakage of contrast medium. To improve the accuracy of CT imaging, optimal contrast administration near the anastomosis appears to be crucial.
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- 2015
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16. Cat scratch disease, a rare cause of hypodense liver lesions, lymphadenopathy and a protruding duodenal lesion, caused by Bartonella henselae.
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van Ierland-van Leeuwen M, Peringa J, Blaauwgeers H, and van Dam A
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- Animals, Anti-Bacterial Agents therapeutic use, Azithromycin therapeutic use, Cat-Scratch Disease diagnosis, Cat-Scratch Disease drug therapy, Cat-Scratch Disease microbiology, Cats, Duodenal Diseases drug therapy, Duodenal Diseases microbiology, Duodenal Diseases pathology, Duodenum microbiology, Duodenum pathology, Female, Humans, Immunoglobulin M blood, Liver microbiology, Liver pathology, Liver Diseases drug therapy, Liver Diseases microbiology, Liver Diseases pathology, Lymph Nodes microbiology, Lymph Nodes pathology, Lymphatic Diseases drug therapy, Lymphatic Diseases microbiology, Lymphatic Diseases pathology, Middle Aged, Bartonella henselae, Cat-Scratch Disease complications, Duodenal Diseases etiology, Liver Diseases etiology, Lymphatic Diseases etiology
- Abstract
A 46-year-old woman presented with right upper abdominal pain and fever. At imaging, enlarged peripancreatic and hilar lymph nodes, as well as hypodense liver lesions, were detected, suggestive of malignant disease. At endoscopy, the mass adjacent to the duodenum was seen as a protruding lesion through the duodenal wall. A biopsy of this lesion, taken through the duodenal wall, showed a histiocytic granulomatous inflammation with necrosis. Serology for Bartonella henselae IgM was highly elevated a few weeks after presentation, consistent with the diagnosis of cat scratch disease. Clinical symptoms subsided spontaneously and, after treatment with azithromycin, the lymphatic masses, liver lesions and duodenal ulceration disappeared completely., (2014 BMJ Publishing Group Ltd.)
- Published
- 2014
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17. A multi-centre randomised double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography.
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Boellaard TN, van der Paardt MP, Hollmann MW, Eberl S, Peringa J, Schouten LJ, Kavaliauskiene G, Runge JH, Tielbeek JA, and Stoker J
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Anesthesia Recovery Period, Double-Blind Method, Humans, Injections, Intravenous, Middle Aged, Monitoring, Physiologic, Pain etiology, Prospective Studies, Surveys and Questionnaires, Young Adult, Alfentanil administration & dosage, Analgesics, Opioid administration & dosage, Anesthetics, Intravenous administration & dosage, Colonography, Computed Tomographic adverse effects, Pain prevention & control
- Abstract
Background: Pain is common during colonic insufflation required for CT colonography. We therefore evaluate whether a single intravenous alfentanil bolus has a clinically relevant analgesic effect compared with placebo in patients undergoing CT colonography., Methods: A prospective multi-centre randomised double-blind placebo-controlled trial was performed in patients scheduled for elective CT colonography. Patients were randomised to receive either a bolus of 7.5 μg/kg alfentanil (n = 45) or placebo (n = 45). The primary outcome was the difference in maximum pain during colonic insufflation on an 11-point numeric rating scale. We defined a clinically relevant effect as a maximum pain reduction of at least 1.3 points. Secondary outcomes included total pain and burden of CT colonography (5-point scale), the most burdensome aspect and side effects. Our primary outcome was tested using a one-sided independent samples t-test., Results: Maximum pain scores during insufflation were lower with alfentanil as compared with placebo, 5.3 versus 3.0 (P < 0.001). Total CT colonography pain and burden were also lower with alfentanil (2.0 vs. 1.6; P = 0.014 and 2.1 vs. 1.7; P = 0.007, respectively). With alfentanil fewer patients rated the insufflation as most burdensome aspect (56.1% vs. 18.6%; P = 0.001). Episodes with desaturations < 90% SpO2 were more common with alfentanil (8.1% vs. 44.4%; P < 0.001, but no clinically relevant desaturations occurred., Conclusions: A low-dose intravenous alfentanil bolus provides a clinically relevant reduction of maximum pain during CT colonography and may improve the CT colonography acceptance, especially for patients with a low pain threshold., Trial Registration: Dutch Trial Register: NTR2902.
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- 2013
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18. A longstanding non-painful tumour of the back.
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van de Vorst IE, Schouten WE, Peringa J, and van den Berk GE
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- Humans, Male, Middle Aged, Tuberculosis, Spinal diagnosis
- Published
- 2012
19. Photo quiz. Bilateral adrenal tumour.
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Bisschop PH, Peringa J, and Blaauwgeers JL
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- Adrenal Gland Diseases diagnostic imaging, Adrenal Gland Diseases pathology, Adrenal Glands pathology, Adult, Biopsy, Diagnosis, Differential, Granuloma microbiology, Granuloma pathology, Histiocytes pathology, Histoplasmosis diagnostic imaging, Histoplasmosis pathology, Humans, Hypertrophy, Male, Tomography, X-Ray Computed, Adrenal Gland Diseases microbiology, Histoplasma isolation & purification, Histoplasmosis microbiology
- Published
- 2003
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