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In this study, lithium niobate (LN) optical modulator devices were fabricated using cost-effective sputtered LN thin films. We successfully achieved a significantly small product of half-wave voltage and interaction electrode length (VπL) of 1.2, 1.0, and 0.75 V cm using red (λ = 638 nm), green (λ = 520 nm), and blue (λ = 473 nm) laser light, respectively. This small VπL is owing to the use of a low dielectric material of LaAlSiInOx for buffer insulator between LN waveguides and electrodes, and the change of geometrical configuration of the electrode. Thus, fabricating visible light modulators at low cost can be realized, and sputtered LN thin films can be adopted for visible light communications and consumer-based applications. [ABSTRACT FROM AUTHOR]

F.Li, Jie ht Footnotes 1 B Disclaimer/Publisher's Note: b The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). [Extracted from the article]

Thanks to the great efforts of our reviewers, I Marine Drugs i was able to maintain its standards for the high quality of its published papers. Thanks to the contribution of our reviewers, in 2021, the median time to first decision was 12 days and the median time to publication was 29 days. [Extracted from the article]

We compared early and delayed Tc-99m ECD SPECT scans in 32 SLE patients (Group 1, definite neuropsychiatric disorders; Group 2, minor neurologic symptoms or normal) with those of normal controls by visual inspection and semi-quantitative evaluation. With visual interpretation, 13 out of 14 patients in Group 1 (93%) and 7 out of 18 patients in Group 2 (39%) had diffuse uneven decrease in early scans. Seven patients in Group 2 (39%) who had normal early scans demonstrated focal decrease in the medial frontal lobe in delayed scans. With cerebral region to cerebellar ratios, in early scans, the medial frontal lobe in Group 1 and Group 2 was significantly lower than in normal controls, and lateral frontal lobe and occipital lobes in Group 1 were significantly lower than in normal controls. Nevertheless, in delayed scans, every cortical region except for the parietal lobe in Groups 1 and 2 was significantly lower than in normal controls. The retention rates in all regions in SLE patients were significantly lower than in normal controls. No case showed SPECT improvement on follow-up studies in either group in spite of clinical improvement. Delayed Tc-99m ECD brain SPECT of high sensitivity might be useful in detecting CNS involvement. Although the SPECT findings did not correlate with the neuropsychiatric symptoms, early and delayed Tc-99m ECD SPECT seems to provide useful objective diagnostic information in SLE patients. [ABSTRACT FROM AUTHOR]