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1. Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer’s disease

Author

Smyth, Leon C. D., Murray, Helen C., Hill, Madison, van Leeuwen, Eve, Highet, Blake, Magon, Nicholas J., Osanlouy, Mahyar, Mathiesen, Sophie N., Mockett, Bruce, Singh-Bains, Malvindar K., Morris, Vanessa K., Clarkson, Andrew N., Curtis, Maurice A., Abraham, Wickliffe C., Hughes, Stephanie M., Faull, Richard L. M., Kettle, Anthony J., Dragunow, Mike, and Hampton, Mark B.

Published
2022
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3. Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease

Author

Smyth, Leon C. D., Highet, Blake, Jansson, Deidre, Wu, Jane, Rustenhoven, Justin, Aalderink, Miranda, Tan, Adelie, Li, Susan, Johnson, Rebecca, Coppieters, Natacha, Handley, Renee, Narayan, Pritika, Singh-Bains, Malvindar K., Schweder, Patrick, Turner, Clinton, Mee, Edward W., Heppner, Peter, Correia, Jason, Park, Thomas I.-H., Curtis, Maurice A., Faull, Richard L. M., and Dragunow, Mike

Published
2022
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5. Human pericytes degrade diverse α-synuclein aggregates

Author

Dieriks, Birger Victor, primary, Highet, Blake, additional, Alik, Ania, additional, Bellande, Tracy, additional, Stevenson, Taylor J., additional, Low, Victoria, additional, Park, Thomas I-H, additional, Correia, Jason, additional, Schweder, Patrick, additional, Faull, Richard L. M., additional, Melki, Ronald, additional, Curtis, Maurice A., additional, and Dragunow, Mike, additional

Published
2022
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6. Additional file 1 of Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer���s disease

Author

Smyth, Leon C. D., Murray, Helen C., Hill, Madison, van Leeuwen, Eve, Highet, Blake, Magon, Nicholas J., Osanlouy, Mahyar, Mathiesen, Sophie N., Mockett, Bruce, Singh-Bains, Malvindar K., Morris, Vanessa K., Clarkson, Andrew N., Curtis, Maurice A., Abraham, Wickliffe C., Hughes, Stephanie M., Faull, Richard L. M., Kettle, Anthony J., Dragunow, Mike, and Hampton, Mark B.

Abstract

Additional file 1. Figure S1: MPO labelling is predominantly confined to neutrophils. Figure S2: Neutrophil accumulation is independent of sex, age, and post-mortem delay. Figure S3: Regional analysis of neutrophil accumulation in APP/PS1 mice. Figure S4: Amyloid-��1-42 does not induce NETosis in vitro. Figure S5: Specificity of antibody labelling across multiple rounds of multiplexed immunohistochemistry. Table S1: Case details of tissue used in tissue microarray and immunohistochemistry experiments. Table S2: Details of antibodies used for these studies.

Published
2022
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