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Additional file 1 of Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer���s disease

Authors :
Smyth, Leon C. D.
Murray, Helen C.
Hill, Madison
van Leeuwen, Eve
Highet, Blake
Magon, Nicholas J.
Osanlouy, Mahyar
Mathiesen, Sophie N.
Mockett, Bruce
Singh-Bains, Malvindar K.
Morris, Vanessa K.
Clarkson, Andrew N.
Curtis, Maurice A.
Abraham, Wickliffe C.
Hughes, Stephanie M.
Faull, Richard L. M.
Kettle, Anthony J.
Dragunow, Mike
Hampton, Mark B.
Publication Year :
2022
Publisher :
figshare, 2022.

Abstract

Additional file 1. Figure S1: MPO labelling is predominantly confined to neutrophils. Figure S2: Neutrophil accumulation is independent of sex, age, and post-mortem delay. Figure S3: Regional analysis of neutrophil accumulation in APP/PS1 mice. Figure S4: Amyloid-��1-42 does not induce NETosis in vitro. Figure S5: Specificity of antibody labelling across multiple rounds of multiplexed immunohistochemistry. Table S1: Case details of tissue used in tissue microarray and immunohistochemistry experiments. Table S2: Details of antibodies used for these studies.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....3dad769b1e6d38bfcc859b60be7761d3
Full Text :
https://doi.org/10.6084/m9.figshare.19418460