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3,982 results on '"Grandi, P."'

1. Spherical bias on the 3D reconstruction of the ICM density profile in galaxy clusters

Author

Veronesi, I., Bartalucci, I., Rasia, E., Molendi, S., Balboni, M., De Grandi, S., Gastaldello, F., Grillo, C., Ghizzardi, S., Lovisari, L., Riva, G., and Rossetti, M.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

X-ray observations of galaxy clusters are routinely used to derive radial distributions of ICM thermdynamical properties such as density and temperature. However, observations allow us to access quantities projected on the celestial sphere only, so that an assumption on the 3D distribution of the ICM is necessary. Usually, spherical geometry is assumed. The aim of this paper is to determine the bias due to this approximation on the reconstruction of ICM density radial profile of a clusters sample and on the intrinsic scatter of the density profiles distribution, when clusters substructures are not masked. We used 98 simulated clusters for which we know the 3D ICM distribution drawn from The Three Hundred project. For each cluster we simulated 40 different observations by projecting the cluster along 40 different lines of sight. We extracted the ICM density profile from each observation assuming the ICM to be spherical distributed. For each line of sight we then considered the mean density profile over the sample and compared it with the 3D density profile given by the simulations. The spherical bias on the density profile is derived by considering the ratio between the observed and the input quantities. We also study the bias on the intrinsic scatter of the density profile distribution performing the same procedure. We find a bias on the density profile, $b_n$, smaller than $10\%$ for $R\lesssim R_{500}$ while it increases up to $\sim 50\%$ for larger radii. The bias on the intrinsic scatter profile, $b_s$, reaches a value of $\approx 100\%$ for $R\approx R_{500}$. The bias on both the analysed quantities strongly depends on the morphology of the objects: for clusters that do not show large scale substructures, both $b_n$ and $b_s$ are reduced by a factor 2, conversely for systems that do show large scale substructures both $b_n$ and $b_s$ increase significantly. [abridged], Comment: Accepted for publication in A&A

Published
2024

2. Neutrinoless Double Beta Decay Sensitivity of the XLZD Rare Event Observatory

Author

XLZD Collaboration, Aalbers, J., Abe, K., Adrover, M., Maouloud, S. Ahmed, Akerib, D. S., Musalhi, A. K. Al, Alder, F., Althueser, L., Amaral, D. W. P., Amarasinghe, C. S., Ames, A., Andrieu, B., Angelides, N., Angelino, E., Antunovic, B., Aprile, E., Araújo, H. M., Armstrong, J. E., Arthurs, M., Babicz, M., Bajpai, D., Baker, A., Balzer, M., Bang, J., Barberio, E., Bargemann, J. W., Barillier, E., Basharina-Freshville, A., Baudis, L., Bauer, D., Bazyk, M., Beattie, K., Beaupere, N., Bell, N. F., Bellagamba, L., Benson, T., Bhatti, A., Biesiadzinski, T. P., Biondi, R., Biondi, Y., Birch, H. J., Bishop, E., Bismark, A., Boehm, C., Boese, K., Bolotnikov, A., Brás, P., Braun, R., Breskin, A., Brew, C. A. J., Brommer, S., Brown, A., Bruni, G., Budnik, R., Burdin, S., Cai, C., Capelli, C., Carini, G., Carmona-Benitez, M. C., Carter, M., Chauvin, A., Chawla, A., Chen, H., Cherwinka, J. J., Chin, Y. T., Chott, N. I., Chavez, A. P. Cimental, Clark, K., Colijn, A. P., Colling, D. J., Conrad, J., Converse, M. V., Coronel, R., Costanzo, D., Cottle, A., Cox, G., Cuenca-García, J. J., Curran, D., Cussans, D., D'Andrea, V., Garcia, L. C. Daniel, Darlington, I., Dave, S., David, A., Davies, G. J., Decowski, M. P., Deisting, A., Delgaudio, J., Dey, S., Di Donato, C., Di Felice, L., Di Gangi, P., Diglio, S., Ding, C., Dobson, J. E. Y., Doerenkamp, M., Drexlin, G., Druszkiewicz, E., Dunbar, C. L., Eitel, K., Elykov, A., Engel, R., Eriksen, S. R., Fayer, S., Fearon, N. M., Ferella, A. D., Ferrari, C., Fieldhouse, N., Fischer, H., Flaecher, H., Flehmke, T., Flierman, M., Fraser, E. D., Fruth, T. M. A., Fujikawa, K., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Gaitskell, R. J., Gallice, N., Galloway, M., Gao, F., Garroum, N., Geffre, A., Genovesi, J., Ghag, C., Ghosh, S., Giacomobono, R., Gibbons, R., Girard, F., Glade-Beucke, R., Glück, F., Gokhale, S., Grandi, L., Green, J., Grigat, J., van der Grinten, M. G. D., Größle, R., Guan, H., Guida, M., Gyorgy, P., Haiston, J. J., Hall, C. R., Hall, T., Hammann, R., Hannen, V., Hansmann-Menzemer, S., Hargittai, N., Hartigan-O'Connor, E., Haselschwardt, S. J., Hernandez, M., Hertel, S. A., Higuera, A., Hils, C., Hiraoka, K., Hoetzsch, L., Hoferichter, M., Homenides, G. J., Hood, N. F., Horn, M., Huang, D. Q., Hughes, S., Hunt, D., Iacovacci, M., Itow, Y., Jacquet, E., Jakob, J., James, R. S., Joerg, F., Jones, S., Kaboth, A. C., Kahlert, F., Kamaha, A. C., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Keller, M., Kemp-Russell, P., Khaitan, D., Kharbanda, P., Kilminster, B., Kim, J., Kirk, R., Kleifges, M., Klute, M., Kobayashi, M., Kodroff, D., Koke, D., Kopec, A., Korolkova, E. V., Kraus, H., Kravitz, S., Kreczko, L., von Krosigk, B., Kudryavtsev, V. A., Kuger, F., Kurita, N., Landsman, H., Lang, R. F., Lawes, C., Lee, J., Lehnert, B., Leonard, D. S., Lesko, K. T., Levinson, L., Li, A., Li, I., Li, S., Liang, S., Liang, Z., Lin, J., Lin, Y. -T., Lindemann, S., Linden, S., Lindner, M., Lindote, A., Lippincott, W. H., Liu, K., Loizeau, J., Lombardi, F., Lopes, J. A. M., Lopes, M. I., Lorenzon, W., Loutit, M., Lu, C., Lucchetti, G. M., Luce, T., Luitz, S., Ma, Y., Macolino, C., Mahlstedt, J., Maier, B., Majewski, P. A., Manalaysay, A., Mancuso, A., Manenti, L., Mannino, R. L., Marignetti, F., Marley, T., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Maupin, C., McCabe, C., McCarthy, M. E., McKinsey, D. N., McLaughlin, J. B., Melchiorre, A., Menéndez, J., Messina, M., Miller, E. H., Milosovic, B., Milutinovic, S., Miuchi, K., Miyata, R., Mizrachi, E., Molinario, A., Monteiro, C. M. B., Monzani, M. E., Morå, K., Moriyama, S., Morrison, E., Morteau, E., Mosbacher, Y., Mount, B. J., Müller, J., Murdy, M., Murphy, A. St. J., Murra, M., Naylor, A., Nelson, H. N., Neves, F., Newstead, J. L., Nguyen, A., Ni, K., O'Hare, C., Oberlack, U., Obradovic, M., Olcina, I., Oliver-Mallory, K. C., Gann, G. D. Orebi, Orpwood, J., Ostrowskiy, I., Ouahada, S., Oyulmaz, K., Paetsch, B., Palladino, K. J., Palmer, J., Pan, Y., Pandurovic, M., Pannifer, N. J., Paramesvaran, S., Patton, S. J., Pellegrini, Q., Penning, B., Pereira, G., Peres, R., Perry, E., Pershing, T., Piastra, F., Pienaar, J., Piepke, A., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qiao, K., Qie, Y., Qin, J., Radeka, S., Radeka, V., Rajado, M., García, D. Ramírez, Ravindran, A., Razeto, A., Reichenbacher, J., Rhyne, C. A., Richards, A., Rischbieter, G. R. C., Riyat, H. S., Rosero, R., Roy, A., Rushton, T., Rynders, D., Saakyan, R., Sanchez, L., Sanchez-Lucas, P., Santone, D., Santos, J. M. F. dos, Sartorelli, G., Sazzad, A. B. M. R., Scaffidi, A., Schnee, R. W., Schreiner, J., Schulte, P., Schulze, H., Eißing, Schumann, M., Schwenck, A., Schwenk, A., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Sharma, S., Shaw, S., Shen, W., Sherman, L., Shi, S., Shi, S. Y., Shimada, T., Shutt, T., Silk, J. J., Silva, C., Simgen, H., Sinev, G., Singh, R., Siniscalco, J., Solmaz, M., Solovov, V. N., Song, Z., Sorensen, P., Soria, J., Stanley, O., Steidl, M., Stenhouse, T., Stevens, A., Stifter, K., Sumner, T. J., Takeda, A., Tan, P. -L., Taylor, D. J., Taylor, W. C., Thers, D., Thümmler, T., Tiedt, D. R., Tönnies, F., Tong, Z., Toschi, F., Tovey, D. R., Tranter, J., Trask, M., Trinchero, G., Tripathi, M., Tronstad, D. R., Trotta, R., Tunnell, C. D., Urquijo, P., Usón, A., Utoyama, M., Vaitkus, A. C., Valentino, O., Valerius, K., Vecchi, S., Velan, V., Vetter, S., de Viveiros, L., Volta, G., Vorkapic, D., Wang, A., Wang, J. J., Wang, W., Wang, Y., Waters, D., Weerman, K. M., Weinheimer, C., Weiss, M., Wenz, D., Whitis, T. J., Wild, K., Williams, M., Wilson, M., Wilson, S. T., Wittweg, C., Wolf, J., Wolfs, F. L. H., Woodford, S., Woodward, D., Worcester, M., Wright, C. J., Wu, V. H. S., üstling, S. W, Wurm, M., Xia, Q., Xing, Y., Xu, D., Xu, J., Xu, Y., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yeh, M., Yu, B., Zavattini, G., Zha, W., Zhong, M., and Zuber, K.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

The XLZD collaboration is developing a two-phase xenon time projection chamber with an active mass of 60 to 80 t capable of probing the remaining WIMP-nucleon interaction parameter space down to the so-called neutrino fog. In this work we show that, based on the performance of currently operating detectors using the same technology and a realistic reduction of radioactivity in detector materials, such an experiment will also be able to competitively search for neutrinoless double beta decay in $^{136}$Xe using a natural-abundance xenon target. XLZD can reach a 3$\sigma$ discovery potential half-life of 5.7$\times$10$^{27}$ yr (and a 90% CL exclusion of 1.3$\times$10$^{28}$ yr) with 10 years of data taking, corresponding to a Majorana mass range of 7.3-31.3 meV (4.8-20.5 meV). XLZD will thus exclude the inverted neutrino mass ordering parameter space and will start to probe the normal ordering region for most of the nuclear matrix elements commonly considered by the community., Comment: 29 pages, 7 figures

Published
2024

3. Responsibility in a Multi-Value Strategic Setting

Author

Parker, Timothy, Grandi, Umberto, and Lorini, Emiliano

Subjects
Computer Science - Artificial Intelligence
Abstract

Responsibility is a key notion in multi-agent systems and in creating safe, reliable and ethical AI. However, most previous work on responsibility has only considered responsibility for single outcomes. In this paper we present a model for responsibility attribution in a multi-agent, multi-value setting. We also expand our model to cover responsibility anticipation, demonstrating how considerations of responsibility can help an agent to select strategies that are in line with its values. In particular we show that non-dominated regret-minimising strategies reliably minimise an agent's expected degree of responsibility.

Published
2024

4. The XLZD Design Book: Towards the Next-Generation Liquid Xenon Observatory for Dark Matter and Neutrino Physics

Author

XLZD Collaboration, Aalbers, J., Abe, K., Adrover, M., Maouloud, S. Ahmed, Akerib, D. S., Musalhi, A. K. Al, Alder, F., Althueser, L., Amaral, D. W. P., Amarasinghe, C. S., Ames, A., Andrieu, B., Angelides, N., Angelino, E., Antunovic, B., Aprile, E., Araújo, H. M., Armstrong, J. E., Arthurs, M., Babicz, M., Bajpai, D., Baker, A., Balzer, M., Bang, J., Barberio, E., Bargemann, J. W., Barillier, E., Basharina-Freshville, A., Baudis, L., Bauer, D., Bazyk, M., Beattie, K., Beaupere, N., Bell, N. F., Bellagamba, L., Benson, T., Bhatti, A., Biesiadzinski, T. P., Biondi, R., Biondi, Y., Birch, H. J., Bishop, E., Bismark, A., Boehm, C., Boese, K., Bolotnikov, A., Brás, P., Braun, R., Breskin, A., Brew, C. A. J., Brommer, S., Brown, A., Bruni, G., Budnik, R., Burdin, S., Cai, C., Capelli, C., Carini, G., Carmona-Benitez, M. C., Carter, M., Chauvin, A., Chawla, A., Chen, H., Cherwinka, J. J., Chin, Y. T., Chott, N. I., Chavez, A. P. Cimental, Clark, K., Colijn, A. P., Colling, D. J., Conrad, J., Converse, M. V., Coronel, R., Costanzo, D., Cottle, A., Cox, G., Cuenca-García, J. J., Curran, D., Cussans, D., D'Andrea, V., Garcia, L. C. Daniel, Darlington, I., Dave, S., David, A., Davies, G. J., Decowski, M. P., Deisting, A., Delgaudio, J., Dey, S., Di Donato, C., Di Felice, L., Di Gangi, P., Diglio, S., Ding, C., Dobson, J. E. Y., Doerenkamp, M., Drexlin, G., Druszkiewicz, E., Dunbar, C. L., Eitel, K., Elykov, A., Engel, R., Eriksen, S. R., Fayer, S., Fearon, N. M., Ferella, A. D., Ferrari, C., Fieldhouse, N., Fischer, H., Flaecher, H., Flehmke, T., Flierman, M., Fraser, E. D., Fruth, T. M. A., Fujikawa, K., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Gaitskell, R. J., Gallice, N., Galloway, M., Gao, F., Garroum, N., Geffre, A., Genovesi, J., Ghag, C., Ghosh, S., Giacomobono, R., Gibbons, R., Girard, F., Glade-Beucke, R., Glück, F., Gokhale, S., Grandi, L., Green, J., Grigat, J., van der Grinten, M. G. D., Größle, R., Guan, H., Guida, M., Gyorgy, P., Haiston, J. J., Hall, C. R., Hall, T., Hammann, R., Hannen, V., Hansmann-Menzemer, S., Hargittai, N., Hartigan-O'Connor, E., Haselschwardt, S. J., Hernandez, M., Hertel, S. A., Higuera, A., Hils, C., Hiraoka, K., Hoetzsch, L., Hoferichter, M., Homenides, G. J., Hood, N. F., Horn, M., Huang, D. Q., Hughes, S., Hunt, D., Iacovacci, M., Itow, Y., Jacquet, E., Jakob, J., James, R. S., Joerg, F., Jones, S., Kaboth, A. C., Kahlert, F., Kamaha, A. C., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Keller, M., Kemp-Russell, P., Khaitan, D., Kharbanda, P., Kilminster, B., Kim, J., Kirk, R., Kleifges, M., Klute, M., Kobayashi, M., Kodroff, D., Koke, D., Kopec, A., Korolkova, E. V., Kraus, H., Kravitz, S., Kreczko, L., von Krosigk, B., Kudryavtsev, V. A., Kuger, F., Kurita, N., Landsman, H., Lang, R. F., Lawes, C., Lee, J., Lehnert, B., Leonard, D. S., Lesko, K. T., Levinson, L., Li, A., Li, I., Li, S., Liang, S., Liang, Z., Lin, J., Lin, Y. -T., Lindemann, S., Linden, S., Lindner, M., Lindote, A., Lippincott, W. H., Liu, K., Loizeau, J., Lombardi, F., Lopes, J. A. M., Lopes, M. I., Lorenzon, W., Loutit, M., Lu, C., Lucchetti, G. M., Luce, T., Luitz, S., Ma, Y., Macolino, C., Mahlstedt, J., Maier, B., Majewski, P. A., Manalaysay, A., Mancuso, A., Manenti, L., Mannino, R. L., Marignetti, F., Marley, T., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Maupin, C., McCabe, C., McCarthy, M. E., McKinsey, D. N., McLaughlin, J. B., Melchiorre, A., Menéndez, J., Messina, M., Miller, E. H., Milosovic, B., Milutinovic, S., Miuchi, K., Miyata, R., Mizrachi, E., Molinario, A., Monteiro, C. M. B., Monzani, M. E., Morå, K., Moriyama, S., Morrison, E., Morteau, E., Mosbacher, Y., Mount, B. J., Müller, J., Murdy, M., Murphy, A. St. J., Murra, M., Naylor, A., Nelson, H. N., Neves, F., Newstead, J. L., Nguyen, A., Ni, K., O'Hare, C., Oberlack, U., Obradovic, M., Olcina, I., Oliver-Mallory, K. C., Gann, G. D. Orebi, Orpwood, J., Ostrowskiy, I., Ouahada, S., Oyulmaz, K., Paetsch, B., Palladino, K. J., Palmer, J., Pan, Y., Pandurovic, M., Pannifer, N. J., Paramesvaran, S., Patton, S. J., Pellegrini, Q., Penning, B., Pereira, G., Peres, R., Perry, E., Pershing, T., Piastra, F., Pienaar, J., Piepke, A., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qiao, K., Qie, Y., Qin, J., Radeka, S., Radeka, V., Rajado, M., García, D. Ramírez, Ravindran, A., Razeto, A., Reichenbacher, J., Rhyne, C. A., Richards, A., Rischbieter, G. R. C., Riyat, H. S., Rosero, R., Roy, A., Rushton, T., Rynders, D., Saakyan, R., Sanchez, L., Sanchez-Lucas, P., Santone, D., Santos, J. M. F. dos, Sartorelli, G., Sazzad, A. B. M. R., Scaffidi, A., Schnee, R. W., Schreiner, J., Schulte, P., Schulze, H., Eißing, Schumann, M., Schwenck, A., Schwenk, A., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Sharma, S., Shaw, S., Shen, W., Sherman, L., Shi, S., Shi, S. Y., Shimada, T., Shutt, T., Silk, J. J., Silva, C., Simgen, H., Sinev, G., Singh, R., Siniscalco, J., Solmaz, M., Solovov, V. N., Song, Z., Sorensen, P., Soria, J., Stanley, O., Steidl, M., Stenhouse, T., Stevens, A., Stifter, K., Sumner, T. J., Takeda, A., Tan, P. -L., Taylor, D. J., Taylor, W. C., Thers, D., Thümmler, T., Tiedt, D. R., Tönnies, F., Tong, Z., Toschi, F., Tovey, D. R., Tranter, J., Trask, M., Trinchero, G., Tripathi, M., Tronstad, D. R., Trotta, R., Tunnell, C. D., Urquijo, P., Usón, A., Utoyama, M., Vaitkus, A. C., Valentino, O., Valerius, K., Vecchi, S., Velan, V., Vetter, S., de Viveiros, L., Volta, G., Vorkapic, D., Wang, A., Wang, J. J., Wang, W., Wang, Y., Waters, D., Weerman, K. M., Weinheimer, C., Weiss, M., Wenz, D., Whitis, T. J., Wild, K., Williams, M., Wilson, M., Wilson, S. T., Wittweg, C., Wolf, J., Wolfs, F. L. H., Woodford, S., Woodward, D., Worcester, M., Wright, C. J., Wu, V. H. S., üstling, S. W, Wurm, M., Xia, Q., Xing, Y., Xu, D., Xu, J., Xu, Y., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yeh, M., Yu, B., Zavattini, G., Zha, W., Zhong, M., and Zuber, K.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract

This report describes the experimental strategy and technologies for a next-generation xenon observatory sensitive to dark matter and neutrino physics. The detector will have an active liquid xenon target mass of 60-80 tonnes and is proposed by the XENON-LUX-ZEPLIN-DARWIN (XLZD) collaboration. The design is based on the mature liquid xenon time projection chamber technology of the current-generation experiments, LZ and XENONnT. A baseline design and opportunities for further optimization of the individual detector components are discussed. The experiment envisaged here has the capability to explore parameter space for Weakly Interacting Massive Particle (WIMP) dark matter down to the neutrino fog, with a 3$\sigma$ evidence potential for the spin-independent WIMP-nucleon cross sections as low as $3\times10^{-49}\rm cm^2$ (at 40 GeV/c$^2$ WIMP mass). The observatory is also projected to have a 3$\sigma$ observation potential of neutrinoless double-beta decay of $^{136}$Xe at a half-life of up to $5.7\times 10^{27}$ years. Additionally, it is sensitive to astrophysical neutrinos from the atmosphere, sun, and galactic supernovae., Comment: 32 pages, 14 figures

Published
2024

5. CHEX-MATE: the intracluster medium entropy distribution in the gravity-dominated regime

Author

Riva, G., Pratt, G. W., Rossetti, M., Bartalucci, I., Kay, S. T., Rasia, E., Gavazzi, R., Umetsu, K., Arnaud, M., Balboni, M., Bonafede, A., Bourdin, H., De Grandi, S., De Luca, F., Eckert, D., Ettori, S., Gaspari, M., Gastaldello, F., Ghirardini, V., Ghizzardi, S., Gitti, M., Lovisari, L., Maughan, B. J., Mazzotta, P., Molendi, S., Pointecouteau, E., Sayers, J., Sereno, M., and Towler, I.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We characterise the entropy profiles of 32 very high mass ($M_{500}>7.75\times10^{14}~M_{\odot}$) galaxy clusters (HIGHMz), selected from the CHEX-MATE sample, to study the intracluster medium (ICM) entropy distribution in a regime where non-gravitational effects are minimised. Using XMM-Newton measurements, we measure the entropy profiles up to ~$R_{500}$ for all objects. The scaled profiles exhibit large dispersion in the central regions, but converge rapidly to the expectation from pure gravitational collapse beyond the core. We quantify the correlation between the ICM morphological parameters and scaled entropy as a function of radius, showing that morphologically relaxed (disturbed) objects have low (high) central entropy. We compare our data to other observational samples, finding differences in normalisation which are linked to the average mass of the samples in question. We find that a weaker mass dependence than self-similar in the scaling (Am ~ -0.25) allows us to minimise the dispersion in the radial range [0.3-0.8]$R_{500}$ for clusters spanning over a decade in mass. The deviation from self-similarity is radially dependent and is more pronounced at small and intermediate radii than at $R_{500}$. We also investigate the distribution of central entropy $K_0$, finding no evidence for bimodality, and outer slopes $\alpha$, which peaks at ~1.1. Using weak lensing masses, we find indication for a small suppression of the scatter (~30%) beyond the core when using masses derived from Yx in the rescaling. Finally, we compare to recent cosmological numerical simulations from THE THREE HUNDRED and MACSIS, finding good agreement with our observational data. These results provide a robust observational benchmark in the gravity-dominated regime and will serve as a future reference for samples at lower mass, higher redshifts, and for ongoing work using cosmological numerical simulations., Comment: 26 pages, 18 figures, 6 tables. Accepted for publication in A&A

Published
2024

6. Model-independent searches of new physics in DARWIN with a semi-supervised deep learning pipeline

Author

Aalbers, J., Abe, K., Adrover, M., Maouloud, S. Ahmed, Althueser, L., Amaral, D. W. P., Andrieu, B., Angelino, E., Martin, D. Antón, Antunovic, B., Aprile, E., Babicz, M., Bajpai, D., Balzer, M., Barberio, E., Baudis, L., Bazyk, M., Bell, N. F., Bellagamba, L., Biondi, R., Biondi, Y., Bismark, A., Boehm, C., Boese, K., Braun, R., Breskin, A., Brommer, S., Brown, A., Bruni, G., Budnik, R., Cai, C., Capelli, C., Chauvin, A., Chavez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Deisting, A., Di Donato, C., Di Gangi, P., Diglio, S., Doerenkamp, M., Drexlin, G., Eitel, K., Elykov, A., Engel, R., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fujikawa, K., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Garroum, N., Giacomobono, R., Girard, F., Glade-Beucke, R., Glück, F., Grandi, L., Grigat, J., Größle, R., Guan, H., Guida, M., Gyorgy, P., Hammann, R., Hannen, V., Hansmann-Menzemer, S., Hargittai, N., Higuera, A., Hils, C., Hiraoka, K., Hoetzsch, L., Hoferichter, M., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., James, R. S., Joerg, F., Kahlert, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Keller, M., Kharbanda, P., Kilminster, B., Kleifges, M., Klute, M., Kobayashi, M., Koke, D., Kopec, A., von Krosigk, B., Kuger, F., LaCascio, L., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, A., Li, S., Liang, S., Liang, Z., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Lucchetti, G. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Maier, B., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Menéndez, J., Messina, M., Milosovic, B., Milutinovic, S., Miuchi, K., Miyata, R., Molinario, A., Monteiro, C. M. B., Morå, K., Moriyama, S., Morteau, E., Mosbacher, Y., Müller, J., Murra, M., Newstead, J. L., Ni, K., O'Hare, C., Oberlack, U., Obradovic, M., Ostrowskiy, I., Ouahada, S., Paetsch, B., Pan, Y., Pandurovic, M., Pellegrini, Q., Peres, R., Piastra, F., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qiao, K., Qin, J., Rajado, M., García, D. Ramírez, Ravindran, A., Razeto, A., Sanchez, L., Sanchez-Lucas, P., Sartorelli, G., Scaffidi, A., Schreiner, J., Schulte, P., Eißing, H. Schulze, Schumann, M., Schwenck, A., Schwenk, A., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Sharma, S., Shen, W., Shi, S. Y., Shimada, T., Simgen, H., Singh, R., Solmaz, M., Stanley, O., Steidl, M., Stevens, A., Takeda, A., Tan, P. -L., Thers, D., Thümmler, T., Tönnies, F., Toschi, F., Trinchero, G., Trotta, R., Tunnell, C. D., Urquijo, P., Utoyama, M., Valerius, K., Vecchi, S., Vetter, S., Volta, G., Vorkapic, D., Wang, W., Weerman, K. M., Weinheimer, C., Weiss, M., Wenz, D., Wilson, M., Wittweg, C., Wolf, J., Wu, V. H. S., Wüstling, S., Wurm, M., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zuber, K.

Subjects
Physics - Instrumentation and Detectors
Abstract

We present a novel deep learning pipeline to perform a model-independent, likelihood-free search for anomalous (i.e., non-background) events in the proposed next generation multi-ton scale liquid Xenon-based direct detection experiment, DARWIN. We train an anomaly detector comprising a variational autoencoder and a classifier on extensive, high-dimensional simulated detector response data and construct a one-dimensional anomaly score optimised to reject the background only hypothesis in the presence of an excess of non-background-like events. We benchmark the procedure with a sensitivity study that determines its power to reject the background-only hypothesis in the presence of an injected WIMP dark matter signal, outperforming the classical, likelihood-based background rejection test. We show that our neural networks learn relevant energy features of the events from low-level, high-dimensional detector outputs, without the need to compress this data into lower-dimensional observables, thus reducing computational effort and information loss. For the future, our approach lays the foundation for an efficient end-to-end pipeline that eliminates the need for many of the corrections and cuts that are traditionally part of the analysis chain, with the potential of achieving higher accuracy and significant reduction of analysis time., Comment: 10 Figures, 3 Tables, 23 Pages (incl. references)

Published
2024

7. First Search for Light Dark Matter in the Neutrino Fog with XENONnT

Author

Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cai, C., Capelli, C., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Deisting, A., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Morabit, S. el, Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyorgy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koke, D., Kopec, A., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Liu, M., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Merz, J., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Szyszka, C., Takeda, A., Tan, P. -L., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.

Subjects
High Energy Physics - Experiment
Abstract

We search for dark matter (DM) with a mass [3,12] $\mathrm{GeV} / c^2$ using an exposure of 3.51 $\mathrm{t} \times \mathrm{y}$ with the XENONnT experiment. We consider spin-independent, spin-dependent, momentum-dependent, mirror DM, and self-interacting DM with a light mediator coupling to Standard Model particles. Using a lowered energy threshold compared to the previous WIMP search, a blind analysis of [0.5, 5.0] $\mathrm{keV}$ nuclear recoil events reveals no significant signal excess over the background. XENONnT excludes spin-independent DM-nucleon cross sections $>2.5 \times 10^{-45} \mathrm{~cm}^2$ at $90 \%$ confidence level for 6 $\mathrm{GeV} / c^2$ DM. The solar ${ }^8 \mathrm{B}$ neutrino coherent elastic neutrino-nucleus scattering background accounts for approximately half of the background in the signal region. In the considered mass range, the DM sensitivity approaches the 'neutrino fog', the limitation where neutrinos produce a signal that is indistinguishable from that of light DM-xenon nucleus scattering.

Published
2024

8. Fermi-LAT detection of the low-luminosity radio galaxy NGC 4278 during the LHAASO campaign

Author

Bronzini, E., Grandi, P., Torresi, E., and Buson, S.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We present a study of the high-energy properties of the compact symmetric object NGC 4278, recently associated with a TeV source by the Large High Altitude Air Shower Observatory (LHAASO) collaboration. We conducted a dedicated analysis of a Fermi-LAT region around NGC 4278, limited to the LHAASO campaign conducted from March 2021 to October 2022. A statistically significant emission ($\mathrm{TS} = 29$) was revealed, spatially consistent with the radio position of NGC 4278 and the LHAASO source. The Fermi-LAT source is detected above $8\,\mathrm{GeV}$, exhibiting a hard spectrum ($\Gamma=1.3\pm0.3$) and a $\gamma$-ray luminosity of $\mathcal{L}_{>100 \, \mathrm{MeV}} \simeq 4\times 10^{41} \, \mathrm{erg\,s^{-1}}$. A serendipitous Swift-XRT observation of NGC 4278 during the TeV campaign reveals the source in a high-state, with a flux $\mathcal{F}_{0.5-8\, \mathrm{keV}} = 5_{-2}^{+3} \times 10^{-12} \, \mathrm{erg \, s^{-1}\, cm^{-2}}$, compatible to the highest luminosity level observed in previous Chandra pointings. The high-energy spectral energy distribution of the source and the intense flux variation observed in the X-ray band support a jet origin for the observed radiation. We suggest that the significant enhancement of the high-energy flux observed during the LHAASO campaign is due to a transient, highly energetic perturbation in the jet. The detection of NGC 4278 at both high- and very high-energies opens new frontiers in studying particle acceleration processes. It reveals that even compact, low-power radio galaxies, not just bright blazars, can exceed the sensitivity thresholds of GeV and TeV instruments, becoming promising targets for the upcoming Cherenkov Telescope Array Observatory (CTAO)., Comment: submitted to ApJL on behalf of the Fermi-LAT collaboration

Published
2024

9. XENONnT Analysis: Signal Reconstruction, Calibration and Event Selection

Author

XENON Collaboration, Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Deisting, A., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyoergy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koke, D., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Merz, J., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.

Subjects
High Energy Physics - Experiment, Physics - Data Analysis, Statistics and Probability
Abstract

The XENONnT experiment, located at the INFN Laboratori Nazionali del Gran Sasso, Italy, features a 5.9 tonne liquid xenon time projection chamber surrounded by an instrumented neutron veto, all of which is housed within a muon veto water tank. Due to extensive shielding and advanced purification to mitigate natural radioactivity, an exceptionally low background level of (15.8 $\pm$ 1.3) events/(tonne$\cdot$year$\cdot$keV) in the (1, 30) keV region is reached in the inner part of the TPC. XENONnT is thus sensitive to a wide range of rare phenomena related to Dark Matter and Neutrino interactions, both within and beyond the Standard Model of particle physics, with a focus on the direct detection of Dark Matter in the form of weakly interacting massive particles (WIMPs). From May 2021 to December 2021, XENONnT accumulated data in rare-event search mode with a total exposure of one tonne $\cdot$ year. This paper provides a detailed description of the signal reconstruction methods, event selection procedure, and detector response calibration, as well as an overview of the detector performance in this time frame. This work establishes the foundational framework for the `blind analysis' methodology we are using when reporting XENONnT physics results., Comment: 27 pages, 23 figures

Published
2024

10. PSZ2 G282.28+49.94, a recently discovered analogue of the famous Bullet Cluster

Author

Bartalucci, I., Rossetti, M., Boschin, W., Girardi, M., Nonino, M., Baraldi, E., Balboni, M., Coe, D., De Grandi, S., Gastaldello, F., Ghizzardi, S., Giacintucci, S., Grillo, C., Harvey, D., Lovisari, L., Molendi, S., Resseguier, T., Riva, G., Venturi, T., and Zitrin, A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present a detailed study of the gas and galaxy properties of the cluster PSZ2 G282.28+49.94 detected in the Planck all-sky survey. The intracluster medium (ICM) of this object at z=0.56 exhibits a cometary-like shape. Combining Chandra and TNG observations, we characterised the spatially resolved thermodynamical properties of the gas and the spatial and velocity distribution of 73 galaxy members. The cluster structure is quite complex with an elongated core region containing the two brightest cluster galaxies and one dense group to the south-east. Since there is no velocity difference between the core and the south-east group, we suggest the presence of a merger along the plane of the sky. This structure is related to complex X-ray and radio features, and thus the merger has likely been caught during the post-merger phase. Comparing the distribution of the ICM and of member galaxies, we find a large offset of $\sim 350$ kpc between the position of the X-ray peak and the centre of a concentration of galaxies, preceding it in the likely direction of motion. This configuration is similar to the famous Bullet Cluster, leading us to dub PSZ2 G282.28+49.94 the "Planck bullet", and represents an ideal situation to provide astrophysical constraints to the self-interaction cross-section ($\sigma/m$) of dark matter particles. These results illustrate the power of a multi-wavelength approach to probe the merging scenario of such complex and distant systems., Comment: Accepted for publication in A&A

Published
2024

11. Proportionality for Constrained Public Decisions

Author

Chingoma, Julian, Grandi, Umberto, and Novaro, Arianna

Subjects
Computer Science - Computer Science and Game Theory
Abstract

We study situations where a group of voters need to take a collective decision over a number of public issues, with the goal of getting a result that reflects the voters' opinions in a proportional manner. Our focus is on interconnected public decisions, where the decision on one or more issues has repercussions on the acceptance or rejection of other public issues in the agenda. We show that the adaptations of classical justified-representation axioms to this enriched setting are always satisfiable only for restricted classes of public agendas. However, the use of suitably adapted well-known decision rules on a class of quite expressive constraints, yields proportionality guarantees that match these justified-representation properties in an approximate sense. We also identify another path to achieving proportionality via an adaptation of the notion of priceability.

Published
2024

12. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k

Author

Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kish, A., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xiao, X., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

DarkSide-20k (DS-20k) is a dark matter detection experiment under construction at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy. It utilises ~100 t of low radioactivity argon from an underground source (UAr) in its inner detector, with half serving as target in a dual-phase time projection chamber (TPC). The UAr cryogenics system must maintain stable thermodynamic conditions throughout the experiment's lifetime of >10 years. Continuous removal of impurities and radon from the UAr is essential for maximising signal yield and mitigating background. We are developing an efficient and powerful cryogenics system with a gas purification loop with a target circulation rate of 1000 slpm. Central to its design is a condenser operated with liquid nitrogen which is paired with a gas heat exchanger cascade, delivering a combined cooling power of >8 kW. Here we present the design choices in view of the DS-20k requirements, in particular the condenser's working principle and the cooling control, and we show test results obtained with a dedicated benchmarking platform at CERN and LNGS. We find that the thermal efficiency of the recirculation loop, defined in terms of nitrogen consumption per argon flow rate, is 95 % and the pressure in the test cryostat can be maintained within $\pm$(0.1-0.2) mbar. We further detail a 5-day cool-down procedure of the test cryostat, maintaining a cooling rate typically within -2 K/h, as required for the DS-20k inner detector. Additionally, we assess the circuit's flow resistance, and the heat transfer capabilities of two heat exchanger geometries for argon phase change, used to provide gas for recirculation. We conclude by discussing how our findings influence the finalisation of the system design, including necessary modifications to meet requirements and ongoing testing activities., Comment: 45 pages, 24 figures

Published
2024

13. Abductive and Contrastive Explanations for Scoring Rules in Voting

Author

Contet, Clément, Grandi, Umberto, and Mengin, Jérôme

Subjects
Computer Science - Artificial Intelligence
Abstract

We view voting rules as classifiers that assign a winner (a class) to a profile of voters' preferences (an instance). We propose to apply techniques from formal explainability, most notably abductive and contrastive explanations, to identify minimal subsets of a preference profile that either imply the current winner or explain why a different candidate was not elected. Formal explanations turn out to have strong connections with classical problems studied in computational social choice such as bribery, possible and necessary winner identification, and preference learning. We design algorithms for computing abductive and contrastive explanations for scoring rules. For the Borda rule, we find a lower bound on the size of the smallest abductive explanations, and we conduct simulations to identify correlations between properties of preference profiles and the size of their smallest abductive explanations., Comment: 10 pages, 2 figures Extended version of a paper in proceedings of ECAI 2024

Published
2024

14. Nonequilibrium control of kagome metals

Author

Grandi, Francesco, Thomale, Ronny, and Kennes, Dante M.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

Exotic quantum order in kagome metals, i.e., quantum materials with a Fermi liquid parent state of electrons on a kagome lattice, has appeared as a vibrant emerging field of condensed matter physics. Already in a small kagome material subclass such as vanadium-based compounds $A$V$_3$Sb$_5$ ($A=$ K, Rb, Cs), the first wave of experimental exploration has brought about manifold evidence for hitherto largely elusive phenomena such as high-temperature charge ordering with orbital currents, nematic order, cascades of charge ordering transitions with hierarchies of ordering vectors, and unconventional superconductivity. We argue that kagome metals promise to be a prototypical ground for the non-equilibrium analysis of quantum order through time-dependent parameter control and manipulation. In particular, we propose to investigate the nematic character of kagome quantum order through light and strain pulses, as well as the nature of time-reversal symmetry breaking and chirality through properly polarized laser pulses., Comment: 10 pages, 4 figures

Published
2024

15. A Lorenz Model for an Anelastic Oberbeck-Boussinesq System

Author

Grandi, Diego, Passerini, Arianna, and Trullo, Manuela

Subjects
Mathematics - Analysis of PDEs, Mathematical Physics
Abstract

In an Oberbeck-Boussinesq model, rigorously derived, which includes compressibility, one could expect that the onset of convection for the B\'enard problem occurs at a higher critical Rayleigh number. Since of the difficulties related to the new partial differential equations, with non constant coefficients and a non divergence-free velocity field, we show the increased stability of the rest state by exploring the related Lorenz approximation system.

Published
2024

16. First Measurement of Solar $^8$B Neutrinos via Coherent Elastic Neutrino-Nucleus Scattering with XENONnT

Author

Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cai, C., Capelli, C., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Deisting, A., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyorgy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koke, D., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Liu, M., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Merz, J., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.

Subjects
Nuclear Experiment, Astrophysics - Solar and Stellar Astrophysics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

We present the first measurement of nuclear recoils from solar $^8$B neutrinos via coherent elastic neutrino-nucleus scattering with the XENONnT dark matter experiment. The central detector of XENONnT is a low-background, two-phase time projection chamber with a 5.9\,t sensitive liquid xenon target. A blind analysis with an exposure of 3.51\,t$\times$y resulted in 37 observed events above 0.5\,keV, with ($26.4^{+1.4}_{-1.3}$) events expected from backgrounds. The background-only hypothesis is rejected with a statistical significance of 2.73\,$\sigma$. The measured $^8$B solar neutrino flux of $(4.7_{-2.3}^{+3.6})\times 10^6\,\mathrm{cm}^{-2}\mathrm{s}^{-1}$ is consistent with results from dedicated solar neutrino experiments. The measured neutrino flux-weighted CE$\nu$NS cross-section on Xe of $(1.1^{+0.8}_{-0.5})\times10^{-39}\,\mathrm{cm}^2$ is consistent with the Standard Model prediction. This is the first direct measurement of nuclear recoils from solar neutrinos with a dark matter detector.

Published
2024

17. Fermionic correlators on the holographic neutron star

Author

Acito, Lucas, Canavesi, Tobías, Grandi, Nicolás, and Lugo, Adrián

Subjects
High Energy Physics - Theory
Abstract

We investigate the fermionic perturbations of the asymptotically AdS background known as holographic neutron star, which represents a highly degenerate state of strongly coupled fermions on a sphere at finite temperature. We calculate the two-point correlator of a fermionic operator and obtain its scaling properties as we approach the critical region of the phase diagram., Comment: 7 pages in the main text, 10 more pages of appendices containing the more detailed calculations, 5 figures

Published
2024

18. MSEval: A Dataset for Material Selection in Conceptual Design to Evaluate Algorithmic Models

Author

Jain, Yash Patawari, Grandi, Daniele, Groom, Allin, Cramer, Brandon, and McComb, Christopher

Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence
Abstract

Material selection plays a pivotal role in many industries, from manufacturing to construction. Material selection is usually carried out after several cycles of conceptual design, during which designers iteratively refine the design solution and the intended manufacturing approach. In design research, material selection is typically treated as an optimization problem with a single correct answer. Moreover, it is also often restricted to specific types of objects or design functions, which can make the selection process computationally expensive and time-consuming. In this paper, we introduce MSEval, a novel dataset which is comprised of expert material evaluations across a variety of design briefs and criteria. This data is designed to serve as a benchmark to facilitate the evaluation and modification of machine learning models in the context of material selection for conceptual design., Comment: arXiv admin note: text overlap with arXiv:2405.03695

Published
2024

19. DarkSide-20k sensitivity to light dark matter particles

Author

Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Walczak, M. B., Wang, Y., Wang, H., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The dual-phase liquid argon time projection chamber is presently one of the leading technologies to search for dark matter particles with masses below 10 GeV/c$^2$. This was demonstrated by the DarkSide-50 experiment with approximately 50 kg of low-radioactivity liquid argon as target material. The next generation experiment DarkSide-20k, currently under construction, will use 1,000 times more argon and is expected to start operation in 2027. Based on the DarkSide-50 experience, here we assess the DarkSide-20k sensitivity to models predicting light dark matter particles, including Weakly Interacting Massive Particles (WIMPs) and sub-GeV/c$^2$ particles interacting with electrons in argon atoms. With one year of data, a sensitivity improvement to dark matter interaction cross-sections by at least one order of magnitude with respect to DarkSide-50 is expected for all these models. A sensitivity to WIMP--nucleon interaction cross-sections below $1\times10^{-42}$ cm$^2$ is achievable for WIMP masses above 800 MeV/c$^2$. With 10 years exposure, the neutrino fog can be reached for WIMP masses around 5 GeV/c$^2$., Comment: submitted to Nature Communications

Published
2024

20. Integrated thermo-optic phase shifters for laser-written photonic circuits operating at cryogenic temperatures

Author

Ceccarelli, Francesco, Rakonjac, Jelena V., Grandi, Samuele, de Riedmatten, Hugues, Osellame, Roberto, and Corrielli, Giacomo

Subjects
Physics - Optics, Quantum Physics
Abstract

Integrated photonics offers compact and stable manipulation of optical signals in miniaturized chips, with the possibility of changing dynamically their functionality by means of integrated phase shifters. Cryogenic operation of these devices is becoming essential for advancing photonic quantum technologies, accommodating components like quantum light sources, single photon detectors and quantum memories operating at liquid helium temperatures. In this work, we report on a programmable glass photonic integrated circuit (PIC) fabricated through femtosecond laser waveguide writing (FLW) and controlled by thermo-optic phase shifters both in a room-temperature and in a cryogenic setting. By taking advantage of a femtosecond laser microstructuring process, we achieved reliable PIC operation with minimal power consumption and confined temperature gradients in both conditions. This advancement marks the first cryogenically-compatible programmable FLW PIC, paving the way for fully integrated quantum architectures realized on a laser-written photonic chip.

Published
2024

21. XENONnT WIMP Search: Signal & Background Modeling and Statistical Inference

Author

XENON Collaboration, Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyoergy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.

Subjects
Physics - Data Analysis, Statistics and Probability, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The XENONnT experiment searches for weakly-interacting massive particle (WIMP) dark matter scattering off a xenon nucleus. In particular, XENONnT uses a dual-phase time projection chamber with a 5.9-tonne liquid xenon target, detecting both scintillation and ionization signals to reconstruct the energy, position, and type of recoil. A blind search for nuclear recoil WIMPs with an exposure of 1.1 tonne-years yielded no signal excess over background expectations, from which competitive exclusion limits were derived on WIMP-nucleon elastic scatter cross sections, for WIMP masses ranging from 6 GeV/$c^2$ up to the TeV/$c^2$ scale. This work details the modeling and statistical methods employed in this search. By means of calibration data, we model the detector response, which is then used to derive background and signal models. The construction and validation of these models is discussed, alongside additional purely data-driven backgrounds. We also describe the statistical inference framework, including the definition of the likelihood function and the construction of confidence intervals., Comment: 20 pages, 10 figures

Published
2024

22. De Sitter geometric inflation from dynamical singularities

Author

Cisterna, Adolfo, Grandi, Nicolas, and Oliva, Julio

Subjects
High Energy Physics - Theory, General Relativity and Quantum Cosmology
Abstract

Within the framework of geometric inflation, where the Friedmann equation is modified to incorporate an infinite series of higher curvature corrections, we describe the emergence of a de Sitter inflationary phase near the poles of an arbitrary dynamical function. Our analysis is quite general and does not depend on any specific choice of cosmological dynamics., Comment: 8 pages, 1 figure

Published
2024

23. Theories for charge-driven nematicity in kagome metals

Author

Grandi, Francesco, Sentef, Michael A., Kennes, Dante M., and Thomale, Ronny

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

Starting from a low-energy model for the band dispersion of the $2 \times 2$ charge-ordered phase of the kagome metals $A$V$_3$Sb$_5$ ($A=$ K, Rb, Cs), we show that nematicity can develop in this state driven either by $4 \times 4$ charge fluctuations preemptive of a $1 \times 4$ charge order (CO), or by an actual zero momentum $d$-wave charge Pomeranchuk instability (PI). We perform an analysis that starts from a Kohn-Luttinger theory in the particle-hole sector, which allows us to establish a criterion for the development of an attractive nematic channel near the onset of the $1 \times 4$ CO and near the $d$-wave charge PI, respectively. We derive an effective charge-fermion model for the $d$-wave PI with a nematic susceptibility given via a random phase approximation (RPA) summation. By contrast, for the finite momentum CO, the RPA scheme breaks down and needs to be improved upon by including Aslamazov-Larkin contributions to the nematic pairing vertex. We then move to the derivation of the Ginzburg-Landau potentials for the $4 \times 4$ CO and for the $d$-wave PI, and we obtain the corresponding expression for the nematic susceptibility at the nematic transition temperature T $ \sim \text{T}_\text{nem}$ in both cases. Our work establishes a relation between the nematicity observed in some of the iron-based superconductors, where the nematic phase might be driven by spin fluctuations, and the vanadium-based kagome metals, where charge fluctuations likely induce nematicity. The two microscopic mechanisms we propose for the stabilization of the nematic state in $A$V$_3$Sb$_5$ are distinguishable by diffusive scattering experiments, meaning that it is possible to gauge which of the two theories, if any, is the most likely to describe this phase. Both mechanisms might also be relevant for the recently discovered titanium-based family $A$Ti$_3$Sb$_5$., Comment: Main text + Supplemental material; 13 figures in total

Published
2024

24. The association between reproductive history and abdominal adipose tissue among postmenopausal women: results from the Womens Health Initiative.

Author

Banack, Hailey, Cook, Claire, Grandi, Sonia, Scime, Natalie, Andary, Rana, Follis, Shawna, Allison, Matthew, Manson, JoAnn, Jung, Su, Wild, Robert, Farland, Leslie, Shadyab, Aladdin, Bea, Jennifer, and Odegaard, Andrew

Subjects
abdominal adiposity, adiposity, aging, body composition, menarche, menopause, obesity, postmenopausal, reproductive health, women’s health, Humans, Female, Postmenopause, Middle Aged, Reproductive History, Menarche, Aged, Prospective Studies, Womens Health, Abdominal Fat, Pregnancy, Body Mass Index, Parity, Menopause, Intra-Abdominal Fat, Adiposity
Abstract

STUDY QUESTION: What is the association between reproductive health history (e.g. age at menarche, menopause, reproductive lifespan) with abdominal adiposity in postmenopausal women? SUMMARY ANSWER: Higher visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) tissue levels were observed among women with earlier menarche, earlier menopause, and greater parity. WHAT IS KNOWN ALREADY: Postmenopausal women are predisposed to accumulation of VAT and SAT. Reproductive health variables are known predictors of overall obesity status in women, defined by BMI. STUDY DESIGN, SIZE, DURATION: This study is a secondary analysis of data collected from the baseline visit of the Womens Health Initiative (WHI). The WHI is a large prospective study of postmenopausal women, including both a randomized trial and observational study. There were 10 184 women included in this analysis. PARTICIPANTS/MATERIALS, SETTING, METHODS: Data were collected from a reproductive health history questionnaire, dual-energy x-ray absorptiometry scans, and anthropometric measures at WHI baseline. Reproductive history was measured via self-report, and included age at menarche, variables related to pregnancy, and age at menopause. Reproductive lifespan was calculated as age at menopause minus age at menarche. Statistical analyses included descriptive analyses and multivariable linear regression models to examine the association between reproductive history with VAT, SAT, total body fat, and BMI. MAIN RESULTS AND THE ROLE OF CHANCE: Women who reported early menarche (15 years had 23 cm2 less VAT (95% CI: -31.4, -14.4) and 47 cm2 less SAT (95% CI: -61.8, -33.4) than women who experienced menarche at age 10 years or earlier. A similar pattern was observed for age at menopause: compared to women who experienced menopause 3 pregnancies) was also associated with VAT and SAT. For example, adjusted beta coefficients for VAT were 8.36 (4.33, 12.4) and 17.9 (12.6, 23.2) comparing three to four pregnancies with the referent, one to two pregnancies. LIMITATIONS, REASONS FOR CAUTION: The WHI reproductive health history questionnaire may be subject to poor recall owing to a long look-back window. Residual confounding may be present given lack of data on early life characteristics, such as maternal and pre-menarche characteristics. WIDER IMPLICATIONS OF THE FINDINGS: This study contributes to our understanding of reproductive lifespan, including menarche and menopause, as an important predictor of late-life adiposity in women. Reproductive health has also been recognized as a sentinel marker for chronic disease in late life. Given established links between adiposity and cardiometabolic outcomes, this research has implications for future research, clinical practice, and public health policy that makes use of reproductive health history as an opportunity for chronic disease prevention. STUDY FUNDING/COMPETING INTEREST(S): HRB and AOO are supported by the National Institute of Health National Institute of Aging (R01AG055018-04). JWB reports royalties from ACSMS Body Composition Assessment Book and consulting fees from the WHI. The remaining authors have no competing interests to declare. TRIAL REGISTRATION NUMBER: N/A.

Published
2024

25. Large Language Models (LLMs) as Agents for Augmented Democracy

Author

Gudiño-Rosero, Jairo, Grandi, Umberto, and Hidalgo, César A.

Subjects
Computer Science - Computers and Society, Computer Science - Artificial Intelligence, Computer Science - Computation and Language
Abstract

We explore an augmented democracy system built on off-the-shelf LLMs fine-tuned to augment data on citizen's preferences elicited over policies extracted from the government programs of the two main candidates of Brazil's 2022 presidential election. We use a train-test cross-validation setup to estimate the accuracy with which the LLMs predict both: a subject's individual political choices and the aggregate preferences of the full sample of participants. At the individual level, we find that LLMs predict out of sample preferences more accurately than a "bundle rule", which would assume that citizens always vote for the proposals of the candidate aligned with their self-reported political orientation. At the population level, we show that a probabilistic sample augmented by an LLM provides a more accurate estimate of the aggregate preferences of a population than the non-augmented probabilistic sample alone. Together, these results indicates that policy preference data augmented using LLMs can capture nuances that transcend party lines and represents a promising avenue of research for data augmentation., Comment: 24 pages main manuscript with 4 figures. 13 pages of supplementary material

Published
2024
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26. Exploring the Capabilities of Large Language Models for Generating Diverse Design Solutions

Author

Ma, Kevin, Grandi, Daniele, McComb, Christopher, and Goucher-Lambert, Kosa

Subjects
Computer Science - Human-Computer Interaction, Computer Science - Artificial Intelligence
Abstract

Access to large amounts of diverse design solutions can support designers during the early stage of the design process. In this paper, we explore the efficacy of large language models (LLM) in producing diverse design solutions, investigating the level of impact that parameter tuning and various prompt engineering techniques can have on the diversity of LLM-generated design solutions. Specifically, LLMs are used to generate a total of 4,000 design solutions across five distinct design topics, eight combinations of parameters, and eight different types of prompt engineering techniques, comparing each combination of parameter and prompt engineering method across four different diversity metrics. LLM-generated solutions are compared against 100 human-crowdsourced solutions in each design topic using the same set of diversity metrics. Results indicate that human-generated solutions consistently have greater diversity scores across all design topics. Using a post hoc logistic regression analysis we investigate whether these differences primarily exist at the semantic level. Results show that there is a divide in some design topics between humans and LLM-generated solutions, while others have no clear divide. Taken together, these results contribute to the understanding of LLMs' capabilities in generating a large volume of diverse design solutions and offer insights for future research that leverages LLMs to generate diverse design solutions for a broad range of design tasks (e.g., inspirational stimuli)., Comment: preprint of journal paper

Published
2024

27. A new hybrid gadolinium nanoparticles-loaded polymeric material for neutron detection in rare event searches

Author

Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cavallo, D., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galinski, G., Gallina, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peddis, D., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Sadashivajois, S., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Slimani, S., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tosi, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Vicini, S., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczynski, R., Wojcik, M. M., Wojcik, M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

Experiments aimed at direct searches for WIMP dark matter require highly effective reduction of backgrounds and control of any residual radioactive contamination. In particular, neutrons interacting with atomic nuclei represent an important class of backgrounds due to the expected similarity of a WIMP-nucleon interaction, so that such experiments often feature a dedicated neutron detector surrounding the active target volume. In the context of the development of DarkSide-20k detector at INFN Gran Sasso National Laboratory (LNGS), several R&D projects were conceived and developed for the creation of a new hybrid material rich in both hydrogen and gadolinium nuclei to be employed as an essential element of the neutron detector. Thanks to its very high cross-section for neutron capture, gadolinium is one of the most widely used elements in neutron detectors, while the hydrogen-rich material is instrumental in efficiently moderating the neutrons. In this paper results from one of the R&Ds are presented. In this effort the new hybrid material was obtained as a poly(methyl methacrylate) (PMMA) matrix, loaded with gadolinium oxide in the form of nanoparticles. We describe its realization, including all phases of design, purification, construction, characterization, and determination of mechanical properties of the new material.

Published
2024
Full Text
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28. Evaluating Large Language Models for Material Selection

Author

Grandi, Daniele, Jain, Yash Patawari, Groom, Allin, Cramer, Brandon, and McComb, Christopher

Subjects
Computer Science - Computation and Language
Abstract

Material selection is a crucial step in conceptual design due to its significant impact on the functionality, aesthetics, manufacturability, and sustainability impact of the final product. This study investigates the use of Large Language Models (LLMs) for material selection in the product design process and compares the performance of LLMs against expert choices for various design scenarios. By collecting a dataset of expert material preferences, the study provides a basis for evaluating how well LLMs can align with expert recommendations through prompt engineering and hyperparameter tuning. The divergence between LLM and expert recommendations is measured across different model configurations, prompt strategies, and temperature settings. This approach allows for a detailed analysis of factors influencing the LLMs' effectiveness in recommending materials. The results from this study highlight two failure modes, and identify parallel prompting as a useful prompt-engineering method when using LLMs for material selection. The findings further suggest that, while LLMs can provide valuable assistance, their recommendations often vary significantly from those of human experts. This discrepancy underscores the need for further research into how LLMs can be better tailored to replicate expert decision-making in material selection. This work contributes to the growing body of knowledge on how LLMs can be integrated into the design process, offering insights into their current limitations and potential for future improvements., Comment: arXiv admin note: text overlap with arXiv:2307.03109 by other authors

Published
2024

29. DesignQA: A Multimodal Benchmark for Evaluating Large Language Models' Understanding of Engineering Documentation

Author

Doris, Anna C., Grandi, Daniele, Tomich, Ryan, Alam, Md Ferdous, Ataei, Mohammadmehdi, Cheong, Hyunmin, and Ahmed, Faez

Subjects
Computer Science - Artificial Intelligence, Computer Science - Computation and Language
Abstract

This research introduces DesignQA, a novel benchmark aimed at evaluating the proficiency of multimodal large language models (MLLMs) in comprehending and applying engineering requirements in technical documentation. Developed with a focus on real-world engineering challenges, DesignQA uniquely combines multimodal data-including textual design requirements, CAD images, and engineering drawings-derived from the Formula SAE student competition. Different from many existing MLLM benchmarks, DesignQA contains document-grounded visual questions where the input image and input document come from different sources. The benchmark features automatic evaluation metrics and is divided into segments-Rule Comprehension, Rule Compliance, and Rule Extraction-based on tasks that engineers perform when designing according to requirements. We evaluate state-of-the-art models (at the time of writing) like GPT-4o, GPT-4, Claude-Opus, Gemini-1.0, and LLaVA-1.5 against the benchmark, and our study uncovers the existing gaps in MLLMs' abilities to interpret complex engineering documentation. The MLLMs tested, while promising, struggle to reliably retrieve relevant rules from the Formula SAE documentation, face challenges in recognizing technical components in CAD images, and encounter difficulty in analyzing engineering drawings. These findings underscore the need for multimodal models that can better handle the multifaceted questions characteristic of design according to technical documentation. This benchmark sets a foundation for future advancements in AI-supported engineering design processes. DesignQA is publicly available at: https://github.com/anniedoris/design_qa/.

Published
2024

30. Elicitron: An LLM Agent-Based Simulation Framework for Design Requirements Elicitation

Author

Ataei, Mohammadmehdi, Cheong, Hyunmin, Grandi, Daniele, Wang, Ye, Morris, Nigel, and Tessier, Alexander

Subjects
Computer Science - Human-Computer Interaction, Computer Science - Artificial Intelligence, Computer Science - Multiagent Systems
Abstract

Requirements elicitation, a critical, yet time-consuming and challenging step in product development, often fails to capture the full spectrum of user needs. This may lead to products that fall short of expectations. This paper introduces a novel framework that leverages Large Language Models (LLMs) to automate and enhance the requirements elicitation process. LLMs are used to generate a vast array of simulated users (LLM agents), enabling the exploration of a much broader range of user needs and unforeseen use cases. These agents engage in product experience scenarios, through explaining their actions, observations, and challenges. Subsequent agent interviews and analysis uncover valuable user needs, including latent ones. We validate our framework with three experiments. First, we explore different methodologies for diverse agent generation, discussing their advantages and shortcomings. We measure the diversity of identified user needs and demonstrate that context-aware agent generation leads to greater diversity. Second, we show how our framework effectively mimics empathic lead user interviews, identifying a greater number of latent needs than conventional human interviews. Third, we showcase that LLMs can be used to analyze interviews, capture needs, and classify them as latent or not. Our work highlights the potential of using LLM agents to accelerate early-stage product development, reduce costs, and increase innovation.

Published
2024

31. Offline tagging of radon-induced backgrounds in XENON1T and applicability to other liquid xenon detectors

Author

Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Martin, D. Antón, Arneodo, F., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruno, G., Budnik, R., Bui, T. K., Cardoso, J. M. R., Chavez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Palacio, J., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

This paper details the first application of a software tagging algorithm to reduce radon-induced backgrounds in liquid noble element time projection chambers, such as XENON1T and XENONnT. The convection velocity field in XENON1T was mapped out using $^{222}\text{Rn}$ and $^{218}\text{Po}$ events, and the root-mean-square convection speed was measured to be $0.30 \pm 0.01$ cm/s. Given this velocity field, $^{214}\text{Pb}$ background events can be tagged when they are followed by $^{214}\text{Bi}$ and $^{214}\text{Po}$ decays, or preceded by $^{218}\text{Po}$ decays. This was achieved by evolving a point cloud in the direction of a measured convection velocity field, and searching for $^{214}\text{Bi}$ and $^{214}\text{Po}$ decays or $^{218}\text{Po}$ decays within a volume defined by the point cloud. In XENON1T, this tagging system achieved a $^{214}\text{Pb}$ background reduction of $6.2^{+0.4}_{-0.9}\%$ with an exposure loss of $1.8\pm 0.2 \%$, despite the timescales of convection being smaller than the relevant decay times. We show that the performance can be improved in XENONnT, and that the performance of such a software-tagging approach can be expected to be further improved in a diffusion-limited scenario. Finally, a similar method might be useful to tag the cosmogenic $^{137}\text{Xe}$ background, which is relevant to the search for neutrinoless double-beta decay., Comment: 17 pages, 19 figures

Published
2024

32. Metal enrichment: the apex accretor perspective

Author

Molendi, S., Ghizzardi, S., De Grandi, S., Balboni, M., Bartalucci, I., Eckert, D., Gastaldello, F., Lovisari, L., Riva, G., and Rossetti, M.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Aims. The goal of this work is to devise a description of the enrichment process in large-scale structure that explains the available observations and makes predictions for future measurements. Methods. We took a spartan approach to this study, employing observational results and algebra to connect stellar assembly in star-forming halos with metal enrichment of the intra-cluster and group medium. Results. On one hand, our construct is the first to provide an explanation for much of the phenomenology of metal enrichment in clusters and groups. It sheds light on the lack of redshift evolution in metal abundance, as well as the small scatter of metal abundance profiles, the entropy versus abundance anti-correlation found in cool core clusters, and the so-called Fe conundrum, along with several other aspects of cluster enrichment. On the other hand, it also allows us to infer the properties of other constituents of large-scale structure. We find that gas that is not bound to halos must have a metal abundance similar to that of the ICM and only about one-seventh to one-third of the Fe in the Universe is locked in stars. A comparable amount is found in gas in groups and clusters and, lastly and most importantly, about three-fifths of the total Fe is contained in a tenuous warm or hot gaseous medium in or between galaxies. We point out that several of our results follow from two critical but well motivated assumptions: 1) the stellar mass in massive halos is currently underestimated and 2) the adopted Fe yield is only marginally consistent with predictions from synthesis models and SN rates. Conclusions. One of the most appealing features of the work presented here is that it provides an observationally grounded construct where vital questions on chemical enrichment in the large-scale structure can be addressed. We hope that it may serve as a useful baseline for future works., Comment: To appear in Astronomy & Astrophysics. Short video presentation at \href{https://www.youtube.com/watch?v=tL2Re9MZjgE}{ }

Published
2024

33. CHEX-MATE: A LOFAR pilot X-ray$-$radio study on five radio halo clusters

Author

Balboni, M., Gastaldello, F., Bonafede, A., Botteon, A., Bartalucci, I., Bourdin, H., Brunetti, G., Cassano, R., De Grandi, S., De Luca, F., Ettori, S., Ghizzardi, S., Gitti, M., Iqbal, A., Johnston-Hollitt, M., Lovisari, L., Mazzotta, P., Molendi, S., Pointecouteau, E., Pratt, G. W., Riva, G., Rossetti, M., Rottgering, H., Sereno, M., van Weeren, R. J., Venturi, T., and Veronesi, I.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The connection between the thermal and non-thermal properties in galaxy clusters hosting radio halos seems fairly well established. However, a comprehensive analysis of such a connection has been made only for integrated quantities (e.g. $L_X - P_{radio}$ relation). In recent years new-generation radio telescopes have enabled the unprecedented possibility to study the non-thermal properties of galaxy clusters on a spatially resolved basis. Here, we perform a pilot study to investigate the mentioned properties on five targets, by combining X-ray data from the CHEX-MATE project with the second data release from the LOFAR Two meter Sky survey. We find a strong correlation ($r_s \sim 0.7$) with a slope less than unity between the radio and X-ray surface brightness. We also report differences in the spatially resolved properties of the radio emission in clusters which show different levels of dynamical disturbance. In particular, less perturbed clusters (according to X-ray parameters) show peaked radio profiles in the centre, with a flattening in the outer regions, while the three dynamically disturbed clusters have steeper profiles in the outer regions. We fit a model to the radio emission in the context of turbulent re-acceleration with a constant ratio between thermal and non-thermal particles energy density and a magnetic field profile linked to the thermal gas density as $B(r) \propto n_{th}^{0.5}$. We found that this simple model cannot reproduce the behaviour of the observed radio emission., Comment: 23 pages, 10 figures, accepted for publication in A&A

Published
2024

34. CHEX-MATE: Robust reconstruction of temperature profiles in galaxy clusters with XMM-Newton

Author

Rossetti, M., Eckert, D., Gastaldello, F., Rasia, E., Pratt, G. W., Ettori, S., Molendi, S., Arnaud, M., Balboni, M., Bartalucci, I., Batalha, R. M., Borgani, S., Bourdin, H., De Grandi, S., De Luca, F., De Petris, M., Forman, W., Gaspari, M., Ghizzardi, S., Iqbal, A., Kay, S., Lovisari, L., Maughan, B. J., Mazzotta, P., Pointecouteau, E., Riva, G., Sayers, J., and Sereno, M.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The "Cluster HEritage project with \xmm: Mass Assembly and Thermodynamics at the Endpoint of structure formation" (CHEX-MATE) is a multi-year Heritage program, to obtain homogeneous XMM-Newton observations of a representative sample of 118 galaxy clusters. The observations are tuned to reconstruct the distribution of the main thermodynamic quantities of the ICM up to $R_{500}$ and to obtain individual mass measurements, via the hydrostatic-equilibrium equation, with a precision of 15-20%. Temperature profiles are a necessary ingredient for the scientific goals of the project and it is thus crucial to derive the best possible temperature measurements from our data. This is why we have built a new pipeline for spectral extraction and analysis of XMM-Newton data, based on a new physically motivated background model and on a Bayesian approach with Markov Chain Monte Carlo (MCMC) methods, that we present in this paper for the first time. We applied this new method to a subset of 30 galaxy clusters representative of the CHEX-MATE sample and show that we can obtain reliable temperature measurements up to regions where the source intensity is as low as 20% of the background, keeping systematic errors below 10%. We compare the median profile of our sample and the best fit slope at large radii with literature results and we find a good agreement with other measurements based on XMM-Newton data. Conversely, when we exclude from our analysis the most contaminated regions, where the source intensity is below 20 of the background, we find significantly flatter profiles, in agreement with predictions from numerical simulations and independent measurements with a combination of Sunyaev-Zeldovich and X-ray imaging data., Comment: Accepted for publication in Astronomy & Astrophysics. Table C.1. available in electronic format at http://xmm-heritage.oas.inaf.it/data/Rossetti24_table_cds.dat

Published
2024
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35. The kagome Hubbard model from a functional renormalization group perspective

Author

Profe, Jonas B., Klebl, Lennart, Grandi, Francesco, Hohmann, Hendrik, Dürrnagel, Matteo, Schwemmer, Tilman, Thomale, Ronny, and Kennes, Dante M.

Subjects
Condensed Matter - Strongly Correlated Electrons, Condensed Matter - Superconductivity
Abstract

The recent discovery of a variety of intricate electronic order in kagome metals has sprouted significant theoretical and experimental interest. From an electronic perspective on the potential microscopic origin of these phases, the most basic model is given by a Hubbard model on the kagome lattice. We employ functional renormalization group (FRG) to analyze the kagome Hubbard model. Through our methodological refinement of FRG both within its N-patch and truncated unity formulation, we resolve previous discrepancies of different FRG approaches (Wang et al., 2013 vs. Kiesel et al., 2013), and analyze both the pure ($p$-type) and mixed ($m$-type) van Hove fillings of the kagome lattice. We further study the RG flow into symmetry broken phases to identify the energetically preferred linear combination of the respective order parameter without any need for additional mean field analysis. Our findings suggest some consistency with recent experiments, and underline the richness of electronic phases already found in the kagome Hubbard model. We also provide a no-go theorem for a complex charge bond ordered phase in the single orbital kagome Hubbard model, suggesting that this model cannot capture aspects of orbital current phases., Comment: 8 pages, 5 figures

Published
2024

36. The XENONnT Dark Matter Experiment

Author

XENON Collaboration, Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Antochi, V. C., Martin, D. Antón, Arneodo, F., Balata, M., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruenner, S., Bruno, G., Budnik, R., Bui, T. K., Cai, C., Cardoso, J. M. R., Cassese, F., Chiarini, A., Cichon, D., Chavez, A. P. Cimental, Colijn, A. P., Conrad, J., Corrieri, R., Cuenca-García, J. J., Cussonneau, J. P., Dadoun, O., D'Andrea, V., Decowski, M. P., De Fazio, B., Di Gangi, P., Diglio, S., Disdier, J. M., Douillet, D., Eitel, K., Elykov, A., Farrell, S., Ferella, A. D., Ferrari, C., Fischer, H., Flierman, M., Form, S., Front, D., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Rosso, A. Gallo, Galloway, M., Gao, F., Gardner, R., Garroum, N., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guerzoni, M., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Howlett, J., Huhmann, C., Iacovacci, M., Iaquaniello, G., Iven, L., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koltman, G., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martella, P., Martens, K., Masbou, J., Masson, D., Masson, E., Mastroianni, S., Mele, E., Messina, M., Michinelli, R., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Nisi, S., Oberlack, U., Orlandi, D., Othegraven, R., Paetsch, B., Palacio, J., Parlati, S., Paschos, P., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Qi, J., Qin, J., García, D. Ramírez, Rynge, M., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shockley, E., Silva, M., Simgen, H., Stephen, J., Stern, M., Stillwell, B. K., Takeda, A., Tan, P. -L., Tatananni, D., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Westermann, J., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

The multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.9 tonnes of cryogenic liquid xenon (8.5 tonnes total mass in cryostat). The experiment is expected to extend the sensitivity to WIMP dark matter by more than an order of magnitude compared to XENON1T, thanks to the larger active mass and the significantly reduced background, improved by novel systems such as a radon removal plant and a neutron veto. This article describes the XENONnT experiment and its sub-systems in detail and reports on the detector performance during the first science run., Comment: 32 pages, 19 figures

Published
2024

37. Biophotons: A Hard Problem

Author

De Paolis, L., Francini, R., Davoli, I., De Matteis, F., Scordo, A., Clozza, A., Grandi, M., Pace, E., Curceanu, C., Grigolini, P., and Benfatto, M.

Subjects
Physics - Biological Physics
Abstract

About a hundred years ago the Russian biologist A. Gurwitsch, based on his experiments with onion plants by measuring their growth rate, made the hypothesis that plants emitted a weak electromagnetic field which somehow influenced cell growth. This interesting observation remained fundamentally ignored by the scientific community and only in the 1950s the electromagnetic emission from some plants was measured using a photomultiplier used in single counting mode. Later, in the 80s several groups in the world started some extensive work to understand the origin and role of this ultra-weak emission, hereby called biophotons, coming from living organisms. Biophotons are an endogenous very small production of photons in the visible energy range in and from cells and organism, and this emission is characteristic of alive organisms. Today there is no doubt that biophotons really exist, this emission has in fact been measured by many groups and on many different living organisms, from humans to bacteria. On the contrary, the origin of biophotons and whether organisms use them in some way to exchange information is not yet well known; no model proposed since now is really capable of reproducing and interpreting the great variety of experimental data coming from the many different living systems measured so far. In this brief review we present our experimental work on biophotons coming from germinating seeds, the main experimental results and some methods we are using to analyze the data in order to open the door for interpretative models of this phenomenon and clarifying its function in the regulation and communication between cells and living organisms. We also discuss some ideas on how to increase the signal-to-noise ratio of the measured signal to have new experimental possibilities that allow the measurement and the characterization of currently unmeasurable quantities., Comment: 19 pages, 7 figures

Published
2024

38. Enabling the Digital Democratic Revival: A Research Program for Digital Democracy

Author

Grossi, Davide, Hahn, Ulrike, Mäs, Michael, Nitsche, Andreas, Behrens, Jan, Boehmer, Niclas, Brill, Markus, Endriss, Ulle, Grandi, Umberto, Haret, Adrian, Heitzig, Jobst, Janssens, Nicolien, Jonker, Catholijn M., Keijzer, Marijn A., Kistner, Axel, Lackner, Martin, Lieben, Alexandra, Mikhaylovskaya, Anna, Murukannaiah, Pradeep K., Proietti, Carlo, Revel, Manon, Rouméas, Élise, Shapiro, Ehud, Sreedurga, Gogulapati, Swierczek, Björn, Talmon, Nimrod, Turrini, Paolo, Terzopoulou, Zoi, and Van De Putte, Frederik

Subjects
Computer Science - Computers and Society
Abstract

This white paper outlines a long-term scientific vision for the development of digital-democracy technology. We contend that if digital democracy is to meet the ambition of enabling a participatory renewal in our societies, then a comprehensive multi-methods research effort is required that could, over the years, support its development in a democratically principled, empirically and computationally informed way. The paper is co-authored by an international and interdisciplinary team of researchers and arose from the Lorentz Center Workshop on ``Algorithmic Technology for Democracy'' (Leiden, October 2022).

Published
2024

39. Telling different unravelings apart via nonlinear quantum-trajectory averages

Author

Piñol, Eloy, Mavrogordatos, Th. K., Keys, Dustin, Veyron, Romain, Sierant, Piotr, García-March, Miguel Angel, Grandi, Samuele, Mitchell, Morgan W., Wehr, Jan, and Lewenstein, Maciej

Subjects
Quantum Physics, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Optics
Abstract

The Gorini-Kossakowski-Sudarshan-Lindblad master equation (ME) governs the density matrix of open quantum systems (OQSs). When an OQS is subjected to weak continuous measurement, its state evolves as a stochastic quantum trajectory, whose statistical average solves the ME. The ensemble of such trajectories is termed an unraveling of the ME. We propose a method to operationally distinguish unravelings produced by the same ME in different measurement scenarios, using nonlinear averages of observables over trajectories. We apply the method to the paradigmatic quantum nonlinear system of resonance fluorescence in a two-level atom. We compare the Poisson-type unraveling, induced by direct detection of photons scattered from the two-level emitter, and the Wiener-type unraveling, induced by phase-sensitive detection of the emitted field. We show that a quantum-trajectory-averaged variance is able to distinguish these measurement scenarios. We evaluate the performance of the method, which can be readily extended to more complex OQSs, under a range of realistic experimental conditions., Comment: 5 pages, 3 figures, with supplementary material, revised version following the published version

Published
2023
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40. Towards the Intuitive Understanding of Quantum World: Sonification of Rabi Oscillations, Wigner functions, and Quantum Simulators

Author

Yamada, Reiko, Piñol, Eloy, Grandi, Samuele, Zakrzewski, Jakub, and Lewenstein, Maciej

Subjects
Quantum Physics
Abstract

Recently, there has been considerable interest in "sonifying" scientific data; however, sonifying quantum processes using the newest quantum technologies, including Noise Intermediate Scale Quantum devices and quantum random number generators, is still an emerging area of research. Music technologists and composers employ the growing accessibility to diverse data from quantum mechanics as musical tools in the hope of generating new sound expressions. How different is the quantum world from the classical one, and is it possible to express the quantum world using sounds? Quantum phenomena are very different from those that we experience in our everyday lives. Thus, it is challenging to understand them intuitively. In this paper, we propose sonification as a method toward an intuitive understanding of various quantum mechanical phenomena, from Rabi oscillations and resonance fluorescence of a single atom through the generation of Schr\"odinger cat states in strong laser field physics to insulator-superfluid transition in quantum many-body systems. This paper illustrates various methods we experimented with in sonification and score representations of quantum data depending on the source data and performance settings., Comment: 8 pages, 12 figures, presented at the 2nd International Symposium on Quantum Computing and Musical Creativity 2023; typos corrected

Published
2023
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41. Superradiant black hole rocket

Author

Acito, Lucas, Grandi, Nicolás E., and Pisani, Pablo

Subjects
General Relativity and Quantum Cosmology, High Energy Physics - Theory
Abstract

We calculate the total thrust resulting from the interaction between charged scalar modes and a superradiant Reissner-Nordstr\"om black hole, when the modes are deflected by a hemispherical perfect mirror located at a finite distance from the black hole's horizon., Comment: 35 pages, 27 figures

Published
2023
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42. CHEX-MATE: Characterization of the intra-cluster medium temperature distribution

Author

Lovisari, L., Ettori, S., Rasia, E., Gaspari, M., Bourdin, H., Campitiello, M. G., Rossetti, M., Bartalucci, I., De Grandi, S., De Luca, F., De Petris, M., Eckert, D., Forman, W., Gastaldello, F., Ghizzardi, S., Jones, C., Kay, S., Kim, J., Maughan, B. J., Mazzotta, P., Pointecouteau, E., Pratt, G. W., Sayers, J., Sereno, M., Simonte, M., and Tozzi, P.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

We study the perturbations in the temperature (and density) distribution for 28 clusters selected from the CHEX-MATE sample to evaluate and characterize the level of inhomogeneities and the related dynamical state of the ICM. We use these spatially resolved 2D distributions to measure the global and radial scatter and identify the regions that deviate the most from the average distribution. During this process, we introduce three dynamical state estimators and produce clean temperature profiles after removing the most deviant regions. We find that the temperature distribution of most of the clusters is skewed towards high temperatures and is well described by a log-normal function. There is no indication that the number of regions deviating more than 1$\sigma$ from the azimuthal value is correlated with the dynamical state inferred from morphological estimators. The removal of these regions leads to local temperature variations up to 10-20% and an average increase of $\sim$5% in the overall cluster temperatures. The measured relative intrinsic scatter within $R_{500}$, $\sigma_{T,int}/T$, has values of 0.17$^{+0.08}_{-0.05}$, and is almost independent of the cluster mass and dynamical state. Comparing the scatter of temperature and density profiles to hydrodynamic simulations, we constrain the average Mach number regime of the sample to $M_{3D}$=0.36$^{+0.16}_{-0.09}$. We infer the ratio between the energy in turbulence and the thermal energy, and translate this ratio in terms of a predicted hydrostatic mass bias $b$, estimating an average value of $b\sim$0.11 (covering a range between 0 and 0.37) within $R_{500}$. This study provides detailed temperature fluctuation measurements for 28 CHEX-MATE clusters which can be used to study turbulence, derive the mass bias, and make predictions on the scaling relation properties., Comment: Accepted for publication in A&A

Published
2023
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43. Design and performance of the field cage for the XENONnT experiment

Author

Aprile, E., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Antochi, V. C., Martin, D. Antón, Arneodo, F., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruenner, S., Bruno, G., Budnik, R., Bui, T. K., Cai, C., Cardoso, J. M. R., Cichon, D., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., Cussonneau, J. P., DÁndrea, V., Decowski, M. P., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Farrell, S., Ferella, A. D., Ferrari, C., Fischer, H., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Rosso, A. Gallo, Galloway, M., Gao, F., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Howlett, J., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koltman, G., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, D., Masson, E., Mastroianni, S., Messina, M., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Palacio, J., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Qi, J., Qin, J., García, D. Ramírez, Šarčević, N., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shockley, E., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The precision in reconstructing events detected in a dual-phase time projection chamber depends on an homogeneous and well understood electric field within the liquid target. In the XENONnT TPC the field homogeneity is achieved through a double-array field cage, consisting of two nested arrays of field shaping rings connected by an easily accessible resistor chain. Rather than being connected to the gate electrode, the topmost field shaping ring is independently biased, adding a degree of freedom to tune the electric field during operation. Two-dimensional finite element simulations were used to optimize the field cage, as well as its operation. Simulation results were compared to ${}^{83m}\mathrm{Kr}$ calibration data. This comparison indicates an accumulation of charge on the panels of the TPC which is constant over time, as no evolution of the reconstructed position distribution of events is observed. The simulated electric field was then used to correct the charge signal for the field dependence of the charge yield. This correction resolves the inconsistent measurement of the drift electron lifetime when using different calibrations sources and different field cage tuning voltages.

Published
2023
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44. Exact oscillations and chaos on a non-Abelian coil

Author

Canfora, Fabrizio, Grandi, Nicolas, Oyarzo, Marcelo, and Oliva, Julio

Subjects
High Energy Physics - Theory, General Relativity and Quantum Cosmology
Abstract

We construct new exact solutions of the Georgi-Glashow model in $3+1$ dimensions. These configurations are periodic in time but lead to a stationary energy density and no energy flux. Nevertheless, they possess a characteristic frequency which manifests itself through non-trivial resonances on test fields. This allows us to interpret them as non-Abelian self sustained coils. We show that for larger energies a transition to chaotic behavior takes place, which we characterize by Poincar\'e sections, Fourier spectra and exponential growth of the geodesic deviation in an effective Jacobi metric, the latter triggered by parametric resonances., Comment: 30 pages, 11 figures. Presentation improved, detailed discussion on transition to chaos included. Accepted for publication in Nuclear Physics B

Published
2023
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45. The XENONnT dark matter experiment.

Author

Aprile, E, Aalbers, J, Abe, K, Ahmed Maouloud, S, Althueser, L, Andrieu, B, Angelino, E, Angevaare, J, Antochi, V, Antón Martin, D, Arneodo, F, Balata, M, Baudis, L, Baxter, A, Bazyk, M, Bellagamba, L, Biondi, R, Bismark, A, Brookes, E, Brown, A, Bruenner, S, Bruno, G, Budnik, R, Bui, T, Cai, C, Cardoso, J, Cassese, F, Chiarini, A, Cichon, D, Cimental Chavez, A, Colijn, A, Conrad, J, Corrieri, R, Cuenca-García, J, Cussonneau, J, Dadoun, O, DAndrea, V, Decowski, M, De Fazio, B, Gangi, P, Diglio, S, Disdier, J, Douillet, D, Eitel, K, Elykov, A, Farrell, S, Ferella, A, Ferrari, C, Fischer, H, Flierman, M, Form, S, Front, D, Fulgione, W, Fuselli, C, Gaemers, P, Gaior, R, Rosso, A, Galloway, M, Gao, F, Gardner, R, Garroum, N, Glade-Beucke, R, Grandi, L, Grigat, J, Guan, H, Guerzoni, M, Guida, M, Hammann, R, Higuera, A, Hils, C, Hoetzsch, L, Hood, N, Howlett, J, Huhmann, C, Iacovacci, M, Iaquaniello, G, Iven, L, Itow, Y, Jakob, J, Joerg, F, Joy, A, Kara, M, Kavrigin, P, Kazama, S, Kobayashi, M, Koltman, G, Kopec, A, Kuger, F, Landsman, H, Lang, R, Levinson, L, Li, I, Li, S, Liang, S, Lindemann, S, Lindner, M, Liu, K, Loizeau, J, Lombardi, F, and Long, J

Abstract

The multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.9 tonnes of cryogenic liquid xenon (8.5 tonnes total mass in cryostat). The experiment is expected to extend the sensitivity to WIMP dark matter by more than an order of magnitude compared to XENON1T, thanks to the larger active mass and the significantly reduced background, improved by novel systems such as a radon removal plant and a neutron veto. This article describes the XENONnT experiment and its sub-systems in detail and reports on the detector performance during the first science run.

Published
2024

46. Measurement of differential ZZ + jets production cross sections in pp collisions at s = 13 TeV

Author

Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Van Mechelen, P., Bols, E. S., D’Hondt, J., Dansana, S., De Moor, A., Delcourt, M., El Faham, H., Lowette, S., Makarenko, I., Müller, D., Sahasransu, A. R., Tavernier, S., Tytgat, M., Van Putte, S., Vannerom, D., Clerbaux, B., De Lentdecker, G., Favart, L., Hohov, D., Jaramillo, J., Khalilzadeh, A., Lee, K., Mahdavikhorrami, M., Malara, A., Paredes, S., Pétré, L., Postiau, N., Thomas, L., Vanden Bemden, M., Vander Velde, C., Vanlaer, P., De Coen, M., Dobur, D., Hong, Y., Knolle, J., Lambrecht, L., Mestdach, G., Rendón, C., Samalan, A., Skovpen, K., Van Den Bossche, N., Wezenbeek, L., Benecke, A., Bruno, G., Caputo, C., Delaere, C., Donertas, I. S., Giammanco, A., Jaffel, K., Jain, Sa., Lemaitre, V., Lidrych, J., Mastrapasqua, P., Mondal, K., Tran, T. T., Wertz, S., Alves, G. A., Coelho, E., Hensel, C., Menezes De Oliveira, T., Moraes, A., Rebello Teles, P., Soeiro, M., Aldá Júnior, W. L., Alves Gallo Pereira, M., Barroso Ferreira Filho, M., Brandao Malbouisson, H., Carvalho, W., Chinellato, J., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., Fonseca De Souza, S., Martins, J., Mora Herrera, C., Mota Amarilo, K., Mundim, L., Nogima, H., Santoro, A., Silva Do Amaral, S. M., Sznajder, A., Thiel, M., Vilela Pereira, A., Bernardes, C. A., Calligaris, L., Fernandez Perez Tomei, T. R., Gregores, E. M., Mercadante, P. G., Novaes, S. F., Orzari, B., Padula, Sandra S., Aleksandrov, A., Antchev, G., Hadjiiska, R., Iaydjiev, P., Misheva, M., Shopova, M., Sultanov, G., Dimitrov, A., Ivanov, T., Litov, L., Pavlov, B., Petkov, P., Petrov, A., Shumka, E., Keshri, S., Thakur, S., Cheng, T., Guo, Q., Javaid, T., Mittal, M., Yuan, L., Bauer, G., Hu, Z., Liu, J., Yi, K., Chen, G. M., Chen, H. S., Chen, M., Iemmi, F., Jiang, C. H., Kapoor, A., Liao, H., Liu, Z.-A., Monti, F., Shahzad, M. A., Sharma, R., Song, J. N., Tao, J., Wang, C., Wang, J., Wang, Z., Zhang, H., Agapitos, A., Ban, Y., Levin, A., Li, C., Li, Q., Mao, Y., Qian, S. J., Sun, X., Wang, D., Yang, H., Zhang, L., Zhou, C., You, Z., Lu, N., Gao, X., Leggat, D., Okawa, H., Zhang, Y., Lin, Z., Lu, C., Xiao, M., Avila, C., Barbosa Trujillo, D. A., Cabrera, A., Florez, C., Fraga, J., Reyes Vega, J. A., Mejia Guisao, J., Ramirez, F., Rodriguez, M., Ruiz Alvarez, J. D., Giljanovic, D., Godinovic, N., Lelas, D., Sculac, A., Kovac, M., Sculac, T., Bargassa, P., Brigljevic, V., Chitroda, B. K., Ferencek, D., Mishra, S., Starodumov, A., Susa, T., Attikis, A., Christoforou, K., Konstantinou, S., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Saka, H., Stepennov, A., Finger, M., Finger, Jr., M., Kveton, A., Ayala, E., Carrera Jarrin, E., Abdelalim, A. A., Salama, E., Mahmoud, M. A., Mohammed, Y., Dewanjee, R. K., Ehataht, K., Kadastik, M., Lange, T., Nandan, S., Nielsen, C., Pata, J., Raidal, M., Tani, L., Veelken, C., Kirschenmann, H., Osterberg, K., Voutilainen, M., Bharthuar, S., Brücken, E., Garcia, F., Havukainen, J., Kallonen, K. T. S., Kim, M. S., Kinnunen, R., Lampén, T., Lassila-Perini, K., Lehti, S., Lindén, T., Lotti, M., Martikainen, L., Myllymäki, M., Rantanen, M. m., Siikonen, H., Tuominen, E., Tuominiemi, J., Luukka, P., Petrow, H., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Faure, J. L., Ferri, F., Ganjour, S., Gras, P., Hamel de Monchenault, G., Lohezic, V., Malcles, J., Rander, J., Rosowsky, A., Sahin, M. Ö., Savoy-Navarro, A., Simkina, P., Titov, M., Baldenegro Barrera, C., Beaudette, F., Buchot Perraguin, A., Busson, P., Cappati, A., Charlot, C., Damas, F., Davignon, O., De Wit, A., Falmagne, G., Fontana Santos Alves, B. A., Ghosh, S., Gilbert, A., Granier de Cassagnac, R., Hakimi, A., Harikrishnan, B., Kalipoliti, L., Liu, G., Motta, J., Nguyen, M., Ochando, C., Portales, L., Salerno, R., Sarkar, U., Sauvan, J. B., Sirois, Y., Tarabini, A., Vernazza, E., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Apparu, D., Bloch, D., Brom, J.-M., Chabert, E. C., Collard, C., Falke, S., Goerlach, U., Grimault, C., Haeberle, R., Le Bihan, A.-C., Sessini, M. A., Van Hove, P., Beauceron, S., Blancon, B., Boudoul, G., Chanon, N., Choi, J., Contardo, D., Depasse, P., Dozen, C., El Mamouni, H., Fay, J., Gascon, S., Gouzevitch, M., Greenberg, C., Grenier, G., Ille, B., Laktineh, I. B., Lethuillier, M., Mirabito, L., Perries, S., Purohit, A., Vander Donckt, M., Verdier, P., Xiao, J., Lomidze, I., Toriashvili, T., Tsamalaidze, Z., Botta, V., Feld, L., Klein, K., Lipinski, M., Meuser, D., Pauls, A., Röwert, N., Teroerde, M., Diekmann, S., Dodonova, A., Eich, N., Eliseev, D., Engelke, F., Erdmann, M., Fackeldey, P., Fischer, B., Hebbeker, T., Hoepfner, K., Ivone, F., Jung, A., Lee, M. y., Mastrolorenzo, L., Merschmeyer, M., Meyer, A., Mukherjee, S., Noll, D., Novak, A., Nowotny, F., Pozdnyakov, A., Rath, Y., Redjeb, W., Rehm, F., Reithler, H., Sarkisovi, V., Schmidt, A., Schuler, S. C., Sharma, A., Stein, A., Torres Da Silva De Araujo, F., Vigilante, L., Wiedenbeck, S., Zaleski, S., Dziwok, C., Flügge, G., Haj Ahmad, W., Kress, T., Nowack, A., Pooth, O., Stahl, A., Ziemons, T., Zotz, A., Aarup Petersen, H., Aldaya Martin, M., Alimena, J., Amoroso, S., An, Y., Baxter, S., Bayatmakou, M., Becerril Gonzalez, H., Behnke, O., Belvedere, A., Bhattacharya, S., Blekman, F., Borras, K., Brunner, D., Campbell, A., Cardini, A., Cheng, C., Colombina, F., Consuegra Rodríguez, S., Correia Silva, G., De Silva, M., Eckerlin, G., Eckstein, D., Estevez Banos, L. I., Filatov, O., Gallo, E., Geiser, A., Giraldi, A., Greau, G., Guglielmi, V., Guthoff, M., Hinzmann, A., Jafari, A., Jeppe, L., Jomhari, N. Z., Kaech, B., Kasemann, M., Kaveh, H., Kleinwort, C., Kogler, R., Komm, M., Krücker, D., Lange, W., Leyva Pernia, D., Lipka, K., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Mendizabal Morentin, M., Metwally, J., Meyer, A. B., Milella, G., Mussgiller, A., Nürnberg, A., Otarid, Y., Pérez Adán, D., Ranken, E., Raspereza, A., Ribeiro Lopes, B., Rübenach, J., Saggio, A., Scham, M., Schnake, S., Schütze, P., Schwanenberger, C., Selivanova, D., Shchedrolosiev, M., Sosa Ricardo, R. E., Sreelatha Pramod, L. P., Stafford, D., Vazzoler, F., Ventura Barroso, A., Walsh, R., Wang, Q., Wen, Y., Wichmann, K., Wiens, L., Wissing, C., Wuchterl, S., Yang, Y., Zimermmane Castro Santos, A., Albrecht, A., Albrecht, S., Antonello, M., Bein, S., Benato, L., Bonanomi, M., Connor, P., Eich, M., El Morabit, K., Fischer, Y., Fröhlich, A., Garbers, C., Garutti, E., Grohsjean, A., Hajheidari, M., Haller, J., Jabusch, H. R., Kasieczka, G., Keicher, P., Klanner, R., Korcari, W., Kramer, T., Kutzner, V., Labe, F., Lange, J., Lobanov, A., Matthies, C., Mehta, A., Moureaux, L., Mrowietz, M., Nigamova, A., Nissan, Y., Paasch, A., Pena Rodriguez, K. J., Quadfasel, T., Raciti, B., Rieger, M., Savoiu, D., Schindler, J., Schleper, P., Schröder, M., Schwandt, J., Sommerhalder, M., Stadie, H., Steinbrück, G., Tews, A., Wolf, M., Brommer, S., Burkart, M., Butz, E., Chwalek, T., Dierlamm, A., Droll, A., Faltermann, N., Giffels, M., Gottmann, A., Hartmann, F., Hofsaess, R., Horzela, M., Husemann, U., Klute, M., Koppenhöfer, R., Link, M., Lintuluoto, A., Maier, S., Mitra, S., Mormile, M., Müller, Th., Neukum, M., Oh, M., Quast, G., Rabbertz, K., Regnery, B., Shadskiy, N., Shvetsov, I., Simonis, H. J., Trevisani, N., Ulrich, R., van der Linden, J., Von Cube, R. 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S., Zarubin, A., Zhizhin, I., and Zhokin, A.

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2024
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47. Precise measurements of W- and Z-boson transverse momentum spectra with the ATLAS detector using pp collisions at s=5.02 TeV and 13 TeV

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Aad, G., Abbott, B., Abeling, K., Abicht, N. J., Abidi, S. H., Aboulhorma, A., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Bourdarios, C. Adam, Adamczyk, L., Adamek, L., Addepalli, S. V., Addison, M. J., Adelman, J., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agaras, M. N., Agarwala, J., Aggarwal, A., Agheorghiesei, C., Ahmad, A., Ahmadov, F., Ahmed, W. S., Ahuja, S., Ai, X., Aielli, G., Aikot, A., Tamlihat, M. Ait, Aitbenchikh, B., Aizenberg, I., Akbiyik, M., Åkesson, T. P. A., Akimov, A. V., Akiyama, D., Akolkar, N. N., Khoury, K. Al, Alberghi, G. L., Albert, J., Albicocco, P., Albouy, G. L., Alderweireldt, S., Aleksa, M., Aleksandrov, I. N., Alexa, C., Alexopoulos, T., Alfonsi, F., Algren, M., Alhroob, M., Ali, B., Ali, H. M. J., Ali, S., Alibocus, S. W., Aliev, M., Alimonti, G., Alkakhi, W., Allaire, C., Allbrooke, B. M. M., Allen, J. F., Flores, C. A. Allendes, Allport, P. P., Aloisio, A., Alonso, F., Alpigiani, C., Estevez, M. Alvarez, Fernandez, A. Alvarez, Cardoso, M. Alves, Alviggi, M. G., Aly, M., Coutinho, Y. Amaral, Ambler, A., Amelung, C., Amerl, M., Ames, C. G., Amidei, D., Santos, S. P. Amor Dos, Amos, K. R., Ananiev, V., Anastopoulos, C., Andeen, T., Anders, J. K., Andrean, S. Y., Andreazza, A., Angelidakis, S., Angerami, A., Anisenkov, A. V., Annovi, A., Antel, C., Anthony, M. T., Antipov, E., Antonelli, M., Anulli, F., Aoki, M., Aoki, T., Pozo, J. A. Aparisi, Aparo, M. A., Bella, L. Aperio, Appelt, C., Apyan, A., Aranzabal, N., Arcangeletti, C., Arce, A. T. H., Arena, E., Arguin, J.-F., Argyropoulos, S., Arling, J.-H., Arnaez, O., Arnold, H., Artoni, G., Asada, H., Asai, K., Asai, S., Asbah, N. A., Assahsah, J., Assamagan, K., Astalos, R., Atashi, S., Atkin, R. J., Atkinson, M., Atmani, H., Atmasiddha, P. A., Augsten, K., Auricchio, S., Auriol, A. D., Austrup, V. A., Avolio, G., Axiotis, K., Azuelos, G., Babal, D., Bachacou, H., Bachas, K., Bachiu, A., Backman, F., Badea, A., Bagnaia, P., Bahmani, M., Bailey, A. J., Bailey, V. R., Baines, J. T., Baines, L., Bakalis, C., Baker, O. K., Bakos, E., Gupta, D. Bakshi, Balakrishnan, V., Balasubramanian, R., Baldin, E. M., Balek, P., Ballabene, E., Balli, F., Baltes, L. M., Balunas, W. K., Balz, J., Banas, E., Bandieramonte, M., Bandyopadhyay, A., Bansal, S., Barak, L., Barakat, M., Barberio, E. L., Barberis, D., Barbero, M., Barel, M. Z., Barends, K. N., Barillari, T., Barisits, M.-S., Barklow, T., Baron, P., Moreno, D. A. Baron, Baroncelli, A., Barone, G., Barr, A. J., Barr, J. D., Navarro, L. Barranco, Barreiro, F., da Costa, J. Barreiro Guimarães, Barron, U., Teixeira, M. G. Barros, Barsov, S., Bartels, F., Bartoldus, R., Barton, A. E., Bartos, P., Basan, A., Baselga, M., Bassalat, A., Basso, M. J., Basson, C. R., Bates, R. L., Batlamous, S., Batley, J. R., Batool, B., Battaglia, M., Battulga, D., Bauce, M., Bauer, M., Bauer, P., Hurrell, L. T. Bazzano, Beacham, J. B., Beau, T., Beauchemin, P. H., Becherer, F., Bechtle, P., Beck, H. 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2024
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48. Observation of the Λb0→J/ψΞ-K+ decay

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Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Valle, A. Escalante Del, Hussain, P. S., Jeitler, M., Krammer, N., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Mechelen, P. Van, Bols, E. S., D’Hondt, J., Dansana, S., De Moor, A., Delcourt, M., El Faham, H., Lowette, S., Makarenko, I., Müller, D., Sahasransu, A. R., Tavernier, S., Tytgat, M., Van Putte, S., Vannerom, D., Clerbaux, B., De Lentdecker, G., Favart, L., Hohov, D., Jaramillo, J., Khalilzadeh, A., Lee, K., Mahdavikhorrami, M., Malara, A., Paredes, S., Pétré, L., Postiau, N., Thomas, L., Bemden, M. Vanden, Velde, C. Vander, Vanlaer, P., De Coen, M., Dobur, D., Hong, Y., Knolle, J., Lambrecht, L., Mestdach, G., Rendón, C., Samalan, A., Skovpen, K., Bossche, N. Van Den, Wezenbeek, L., Benecke, A., Bruno, G., Caputo, C., Delaere, C., Donertas, I. S., Giammanco, A., Jaffel, K., Jain, Sa., Lemaitre, V., Lidrych, J., Mastrapasqua, P., Mondal, K., Tran, T. T., Wertz, S., Alves, G. A., Coelho, E., Hensel, C., De Oliveira, T. Menezes, Moraes, A., Teles, P. Rebello, Soeiro, M., Júnior, W. L. Aldá, Pereira, M. Alves Gallo, Filho, M. Barroso Ferreira, Malbouisson, H. Brandao, Carvalho, W., Chinellato, J., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Souza, S. Fonseca, Martins, J., Herrera, C. Mora, Amarilo, K. Mota, Mundim, L., Nogima, H., Santoro, A., Sznajder, A., Thiel, M., Pereira, A. Vilela, Bernardes, C. A., Calligaris, L., Tomei, T. R. Fernandez Perez, Gregores, E. M., Mercadante, P. G., Novaes, S. 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Sreelatha, Stafford, D., Vazzoler, F., Barroso, A. Ventura, Walsh, R., Wang, Q., Wen, Y., Wichmann, K., Wiens, L., Wissing, C., Wuchterl, S., Yang, Y., Santos, A. Zimermmane Castro, Albrecht, A., Albrecht, S., Antonello, M., Bein, S., Benato, L., Bonanomi, M., Connor, P., Eich, M., El Morabit, K., Fischer, Y., Fröhlich, A., Garbers, C., Garutti, E., Grohsjean, A., Hajheidari, M., Haller, J., Jabusch, H. R., Kasieczka, G., Keicher, P., Klanner, R., Korcari, W., Kramer, T., Kutzner, V., Labe, F., Lange, J., Lobanov, A., Matthies, C., Mehta, A., Moureaux, L., Mrowietz, M., Nigamova, A., Nissan, Y., Paasch, A., Rodriguez, K. J. 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M., Lista, L., Paolucci, P., Rossi, B., Sciacca, C., Ardino, R., Azzi, P., Bacchetta, N., Bisello, D., Bortignon, P., Bragagnolo, A., Carlin, R., Dorigo, T., Gasparinis, F., Gasparini, U., Gozzelino, A., Grosso, G., Layer, L., Lusiani, E., Margoni, M., Meneguzzo, A. T., Migliorini, M., Pazzini, J., Ronchese, P., Rossin, R., Simonetto, F., Strong, G., Tosi, M., Triossi, A., Ventura, S., Yarar, H., Zanetti, M., Zotto, P., Zucchetta, A., Zumerle, G., Zeid, S. Abu, Aimè, C., Braghieri, A., Calzaferri, S., Fiorina, D., Montagna, P., Re, V., Riccardi, C., Salvini, P., Vai, I., Vitulo, P., Ajmal, S., Asenov, P., Bilei, G. M., Ciangottini, D., Fanò, L., Magherini, M., Mantovani, G., Mariani, V., Menichelli, M., Moscatelli, F., Piccinelli, A., Presilla, M., Rossi, A., Santocchia, A., Spiga, D., Tedeschi, T., Azzurri, P., Bagliesi, G., Bhattacharya, R., Bianchini, L., Boccali, T., Bossini, E., Bruschini, D., Castaldi, R., Ciocci, M. 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S., Zarubin, A., Zhizhin, I., and Zhokin, A.

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2024
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49. Search for a resonance decaying to a W boson and a photon in proton-proton collisions at s = 13 TeV using leptonic W boson decays

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Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Hussain, P. S., Jeitler, M., Krammer, N., Li, A., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Janssen, T., Van Laer, T., Van Mechelen, P., Breugelmans, N., D’Hondt, J., Dansana, S., De Moor, A., Delcourt, M., Heyen, F., Lowette, S., Makarenko, I., Müller, D., Tavernier, S., Tytgat, M., Van Onsem, G. P., Van Putte, S., Vannerom, D., Bilin, B., Clerbaux, B., Das, A. K., De Lentdecker, G., Evard, H., Favart, L., Gianneios, P., Jaramillo, J., Khalilzadeh, A., Khan, F. A., Lee, K., Mahdavikhorrami, M., Malara, A., Paredes, S., Shahzad, M. A., Thomas, L., Vanden Bemden, M., Vander Velde, C., Vanlaer, P., De Coen, M., Dobur, D., Gokbulut, G., Hong, Y., Knolle, J., Lambrecht, L., Marckx, D., Mota Amarilo, K., Samalan, A., Skovpen, K., Van Den Bossche, N., van der Linden, J., Wezenbeek, L., Benecke, A., Bethani, A., Bruno, G., Caputo, C., De Favereau De Jeneret, J., Delaere, C., Donertas, I. S., Giammanco, A., Guzel, A. O., Jain, Sa., Lemaitre, V., Lidrych, J., Mastrapasqua, P., Tran, T. T., Wertz, S., Alves, G. A., Alves Gallo Pereira, M., Coelho, E., Correia Silva, G., Hensel, C., Menezes De Oliveira, T., Mora Herrera, C., Moraes, A., Rebello Teles, P., Soeiro, M., Vilela Pereira, A., Aldá Júnior, W. L., Barroso Ferreira Filho, M., Brandao Malbouisson, H., Carvalho, W., Chinellato, J., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., Fonseca De Souza, S., Gomes De Souza, R., Macedo, M., Martins, J., Mundim, L., Nogima, H., Pinheiro, J. P., Santoro, A., Sznajder, A., Thiel, M., Bernardes, C. A., Calligaris, L., Fernandez Perez Tomei, T. R., Gregores, E. M., Lopes Da Costa, B., Maietto Silverio, I., Mercadante, P. G., Novaes, S. F., Orzari, B., Padula, Sandra S., Aleksandrov, A., Antchev, G., Hadjiiska, R., Iaydjiev, P., Misheva, M., Shopova, M., Sultanov, G., Dimitrov, A., Litov, L., Pavlov, B., Petkov, P., Petrov, A., Shumka, E., Keshri, S., Laroze, D., Thakur, S., Cheng, T., Javaid, T., Yuan, L., Hu, Z., Liang, Z., Liu, J., Yi, K., Chen, G. M., Chen, H. S., Chen, M., Iemmi, F., Jiang, C. H., Kapoor, A., Liao, H., Liu, Z.-A., Sharma, R., Song, J. N., Tao, J., Wang, C., Wang, J., Wang, Z., Zhang, H., Zhao, J., Agapitos, A., Ban, Y., Deng, S., Guo, B., Jiang, C., Levin, A., Li, C., Li, Q., Mao, Y., Qian, S., Qian, S. J., Qin, X., Sun, X., Wang, D., Yang, H., Zhang, L., Zhao, Y., Zhou, C., Yang, S., You, Z., Jaffel, K., Lu, N., Bauer, G., Li, B., Zhang, J., Gao, X., Li, Y., Lin, Z., Lu, C., Xiao, M., Avila, C., Barbosa Trujillo, D. A., Cabrera, A., Florez, C., Fraga, J., Reyes Vega, J. A., Ramirez, F., Rendón, C., Rodriguez, M., Ruales Barbosa, A. A., Ruiz Alvarez, J. D., Giljanovic, D., Godinovic, N., Lelas, D., Sculac, A., Kovac, M., Petkovic, A., Sculac, T., Bargassa, P., Brigljevic, V., Chitroda, B. K., Ferencek, D., Jakovcic, K., Mishra, S., Starodumov, A., Susa, T., Attikis, A., Christoforou, K., Hadjiagapiou, A., Leonidou, C., Mousa, J., Nicolaou, C., Paizanos, L., Ptochos, F., Razis, P. A., Rykaczewski, H., Saka, H., Stepennov, A., Finger, M., Finger, Jr., M., Kveton, A., Carrera Jarrin, E., Assran, Y., El-mahdy, B., Elgammal, S., Mahmoud, M. A., Mohammed, Y., Ehataht, K., Kadastik, M., Lange, T., Nandan, S., Nielsen, C., Pata, J., Raidal, M., Tani, L., Veelken, C., Kirschenmann, H., Osterberg, K., Voutilainen, M., Bharthuar, S., Bin Norjoharuddeen, N., Brücken, E., Garcia, F., Inkaew, P., Kallonen, K. T. 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J., Crossman, B., Joshi, B. M., Kapsiak, C., Krohn, M., Mahon, D., Mans, J., Marzocchi, B., Revering, M., Rusack, R., Saradhy, R., Strobbe, N., Bloom, K., Claes, D. R., Haza, G., Hossain, J., Joo, C., Kravchenko, I., Siado, J. E., Tabb, W., Vagnerini, A., Wightman, A., Yan, F., Yu, D., Bandyopadhyay, H., Hay, L., Hsia, H. w., Iashvili, I., Kalogeropoulos, A., Kharchilava, A., Morris, M., Nguyen, D., Pekkanen, J., Rappoccio, S., Rejeb Sfar, H., Williams, A., Young, P., Alverson, G., Barberis, E., Bonilla, J., Dervan, J., Haddad, Y., Han, Y., Krishna, A., Li, J., Lu, M., Madigan, G., Mccarthy, R., Morse, D. M., Nguyen, V., Orimoto, T., Parker, A., Skinnari, L., Wood, D., Bueghly, J., Dittmer, S., Hahn, K. A., Liu, Y., Miao, Y., Monk, D. G., Schmitt, M. H., Taliercio, A., Velasco, M., Agarwal, G., Band, R., Bucci, R., Castells, S., Das, A., Goldouzian, R., Hildreth, M., Ho, K. W., Hurtado Anampa, K., Ivanov, T., Jessop, C., Lannon, K., Lawrence, J., Loukas, N., Lutton, L., Mariano, J., Marinelli, N., Mcalister, I., McCauley, T., Mcgrady, C., Moore, C., Musienko, Y., Nelson, H., Osherson, M., Piccinelli, A., Ruchti, R., Townsend, A., Wan, Y., Wayne, M., Yockey, H., Zarucki, M., Zygala, L., Basnet, A., Bylsma, B., Carrigan, M., Durkin, L. S., Hill, C., Joyce, M., Nunez Ornelas, M., Wei, K., Winer, B. L., Yates, B. R., Bouchamaoui, H., Das, P., Dezoort, G., Elmer, P., Frankenthal, A., Greenberg, B., Haubrich, N., Kennedy, K., Kopp, G., Kwan, S., Lange, D., Loeliger, A., Marlow, D., Ojalvo, I., Olsen, J., Stickland, D., Tully, C., Malik, S., Bakshi, A. S., Chandra, S., Chawla, R., Gu, A., Gutay, L., Jones, M., Jung, A. W., Koshy, A. M., Liu, M., Negro, G., Neumeister, N., Paspalaki, G., Piperov, S., Scheurer, V., Schulte, J. F., Stojanovic, M., Thieman, J., Virdi, A. 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S., Zarubin, A., Zhizhin, I., and Zhokin, A.

Published
2024
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50. Quantitative micro-CT-derived biomarkers elucidate age-related lung fibrosis in elder mice

Author

Davide Buseghin, Andrea Grandi, Erica Ferrini, Gino Villetti, Roberta Ciccimarra, Nicola Sverzellati, Andrea Aliverti, Francesca Pennati, and Franco Fabio Stellari

Subjects
Age, Bleomycin model, Lung fibrosis, IPF, Micro-computed tomography, Nintedanib, Diseases of the respiratory system, RC705-779
Abstract

Abstract Background Idiopathic Pulmonary Fibrosis (IPF), prevalently affecting individuals over 60 years of age, has been mainly studied in young mouse models. The limited efficacy of current treatments underscores the need for animal models that better mimic an aged patient population. We addressed this by inducing pulmonary fibrosis in aged mice, using longitudinal micro-CT imaging as primary readout, with special attention to animal welfare. Methods A double bleomycin dose was administered to 18–24 months-old male C57Bl/6j mice to induce pulmonary fibrosis. Bleomycin dosage was reduced to as low as 75% compared to that commonly administered to young (8–12 weeks-old) mice, resulting in long-term lung fibrosis without mortality, complying with animal welfare guidelines. After fibrosis induction, animals received Nintedanib once-daily for two weeks and longitudinally monitored by micro-CT, which provided structural and functional biomarkers, followed by post-mortem histological analysis as terminal endpoint. Results Compared to young mice, aged animals displayed increased volume, reduced tissue density and function, and marked inflammation. This increased vulnerability imposed a bleomycin dosage reduction to the lowest tested level (2.5 µg/mouse), inducing a milder, yet persistent, fibrosis, while preserving animal welfare. Nintedanib treatment reduced fibrotic lesions and improved pulmonary function. Conclusions Our data identify a downsized bleomycin treatment that allows to achieve the best trade-off between fibrosis induction and animal welfare, a requirement for antifibrotic drug testing in aged lungs. Nintedanib displayed significant efficacy in this lower-severity disease model, suggesting potential patient stratification strategies. Lung pathology was quantitatively assessed by micro-CT, pointing to the value of longitudinal endpoints in clinical trials.

Published
2024
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