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Measles is a highly contagious, vaccine-preventable disease that requires high population immunity in order for transmission to be interrupted. All 6 WHO regions have committed themselves to eliminating measles; however, no region has achieved and sustained elimination. This report describes progress in measles elimination during 2000-2022. Estimated coverage with the first dose of measles-containing vaccine (MCV) worldwide increased from 72% to 86% between 2000 and 2019 and then decreased to 81% in 2021 during the coronavirus disease 2019 (COVID-19) pandemic, the lowest coverage rate since 2008. In 2022, MCV1 coverage increased to 83%. Only 72 (50%) of 144 countries that reported measles cases achieved the measles surveillance indicator target of >2 discarded cases per 100 000 population in 2022. During 2021-2022, estimated measles cases increased by 18%, from 7 802 000 to 9 232 300, and the number of countries experiencing large or disruptive outbreaks increased from 22 to 37. The estimated number of measles deaths increased by 43% during 2021-2022, from 95 000 to 136 200. Nonetheless, an estimated 57 million measles deaths were averted by vaccination during 2000-2022. In 2022, measles vaccination coverage and global surveillance showed some recovery from the setbacks during the COVID-19 pandemic; however, coverage decreased in low-income countries, and, globally, years of suboptimal immunization coverage left millions of children unprotected. Setbacks in coverage during the COVID-19 pandemic must be reversed by renewed efforts to vaccinate all children with 2 MCV doses, strengthen surveillance, prevent outbreaks and accelerate progress towards elimination. La rougeole est une maladie a prevention vaccinale qui est hautement contagieuse et dont la transmission ne peut etre interrompue qu'en presence d'une forte immunite collective. Les 6 Regions de l'OMS se sont toutes engagees a eliminer la rougeole, mais a ce jour, aucune d'entre elles n'a atteint durablement cet objectif. Le present rapport decrit les progres accomplis vers l'elimination de la rougeole au cours de la periode 2000-2022. La couverture mondiale de la vaccination par la premiere dose de vaccin a valence rougeole (MCV) a progresse entre 2000 et 2019, passant de 72% a 86%, mais a ensuite recule pendant la pandemie de COVID-19 pour s'etablir a 81% en 2021, soit le taux le plus faible enregistre depuis 2008. En 2022, la couverture par le MCV1 est remontee a 83%. En 2022, seuls 72 (50%) des 144 pays ayant signale des cas de rougeole ont atteint la cible de l'indicateur de surveillance de la rougeole relatif au nombre de cas ecartes, a savoir >2 cas ecartes pour 100 000 habitants. Dans la periode 2021-2022, le nombre de cas de rougeole signales a augmente de 18%, passant de 7 802 000 a 9 232 300, et, le nombre de pays confrontes a des flambees epidemiques de grande ampleur ou perturbatrices de rougeole est passe de 22 a 37, et le nombre estime de deces dus a la rougeole a augmente de 43%, passant de 95 000 a 136 200. Neanmoins, on estime qu'entre 2000 et 2022, la vaccination a permis d'eviter 57 millions de deces dus a la rougeole. En 2022, on a constate des signes de relevement de la couverture vaccinale et de la surveillance mondiale de la rougeole apres les revers subis lors de la pandemie de COVID-19; la couverture vaccinale a toutefois diminuee dans les pays a faible revenu et, apres des annees de couverture sousoptimale, des millions d'enfants dans le monde restent sans protection contre la maladie. Il est urgent d'inverser le recul de la couverture enregistre pendant la pandemie de COVID-19 en redoublant d'efforts pour vacciner tous les enfants par 2 doses de MCV, renforcer la surveillance, prevenir les flambees epidemiques et accelerer les progres vers l'elimination., Introduction All 6 WHO regions have committed themselves to eliminating measles. (1) The Immunization Agenda 2030 (IA2030) 2 includes measles elimination as a core indicator of impact. IA2030 highlights the [...]

In 2020, the World Health Assembly endorsed the Immunization Agenda 2030 (IA2030), the 2021-2030 global strategy for a world in which everyone, everywhere, at every age fully benefits from vaccines. This report reviews trends in WHO and United Nations Children's Fund (UNICEF) estimates of global, regional and national immunization coverage up to 2022 and documents progress in improving coverage to reduce the number of children who have not received the first dose of a diphtheria-tetanus-pertussis-containing vaccine (DTPcvl) (zero-dose children) worldwide by 50% and to increase coverage with 3 DTPcv doses (DTPcv3). Worldwide, coverage with [greater than or equal to]1 dose DTPcvl increased from 86% in 2021 to 89% in 2022, remaining below the 90% coverage achieved in 2019. Estimated DTPcv3 coverage increased from 81% in 2021 to 84% in 2022 but also remained below the 2019 coverage of 86%. Worldwide in 2022, 14.3 million children were not vaccinated with DTPcv1, a 21% decrease from 18.1 million in 2021 but an 11% increase from 12.9 million in 2019. Most children (84%) who did not receive DTPcv1 in 2022 lived in low- and lower-middle-income countries. Global immunization rates recovered from the reduced levels associated with the coronavirus disease 2019 (COVID-19) pandemic in 2022, but progress was unevenly distributed, especially in low-income countries. Urgent action is needed to provide incompletely vaccinated children with catch-up vaccinations that were missed during the pandemic, restore national vaccination coverage to pre-pandemic levels, strengthen immunization programmes to build resilience to future unforeseen public health events, and further improve coverage to protect children from vaccine-preventable diseases. En 2020, l'Assemblee mondiale de la Sante a approuve le Programme de vaccination a l'horizon 2030 (IA2030), la strategie mondiale 2021-2030 pour un monde oU chaque individu, oU qu'il se trouve et quel que soit son age, beneficie pleinement des vaccins. Ce rapport examine l'evolution des estimations de l'OMS et du Fonds des Nations Unies pour l'enfance (UNICEF) de la couverture vaccinale mondiale, regionale et nationale jusqu'en 2022 et documente les progres accomplis dans l'amelioration de la couverture vaccinale visant a reduire de 50% le nombre d'enfants qui n'ont pas recu la premiere dose du vaccin antidiphterique-antitetanique-anticoquelucheux (DTC1) (enfants dits <>) dans le monde et a augmenter la couverture vaccinale par la troisieme dose de DTC (DTC3). A l'echelle mondiale, la couverture vaccinale par [greater than or equal to]1 dose de DTC a augmente, passant de 86% en 2021 a 89% en 2022, mais reste inferieure a la couverture de 90% atteinte en 2019. La couverture estimee par la DTC3 a egalement augmente, passant de 81% en 2021 a 84% en 2022, mais demeure inferieure a la couverture de 86% en 2019. En 2022, dans le monde, 14,3 millions d'enfants n'ont pas recu la DTC1, un chiffre en baisse de 21% par rapport aux 18,1 millions d'enfants en 2021, mais en augmentation de 11% par rapport aux 12,9 millions d'enfants en 2019. La plupart des enfants (84%) qui n'ont pas recu la DTC1 en 2022 vivaient dans des pays a revenu faible ou intermediaire de la tranche inferieure. Les taux de vaccination ont progresse a l'echelle mondiale, apres un recul associe a la pandemie de maladie a coronavirus 2019 (COVID-19) en 2022, mais de maniere inegale, en particulier dans les pays a faible revenu. Il est urgent d'agir pour rattraper la vaccination des enfants incompletement vaccines parce qu'ils n'ont pas pu etre atteints lors de la pandemie, retablir la couverture vaccinale nationale aux niveaux d'avant la pandemie, renforcer les programmes de vaccination afin d'accroitre la resilience face a de futurs evenements de sante publique imprevus et ameliorer encore la couverture vaccinale pour proteger les enfants contre les maladies evitables par la vaccination., Introduction The Expanded Programme on Immunization was established by WHO in 1974 to ensure that every infant in the world receives vaccines against diphtheria, tetanus, pertussis, poliomyelitis, measles and tuberculosis. [...]

Following the emergence of SARS-CoV-2 in late 2019, transmission expanded globally and on 30 January 2020, COVID-19 was declared as a public health emergency of international concern. (1) Analysis of [...]

All 6 WHO regions have committed themselves to eliminate measles. (1) The aim of the Immunization Agenda 2021-2030 (IA2030) (2) is to achieve regional targets as a core indicator of [...]

In 2012, the World Health Assembly (WHA) endorsed the Global Vaccine Action Plan (GVAP), (1) with the objective of eliminating measles (2) in 5 of the 6 WHO regions by [...]

The aim of the Immunization agenda 2030 (IA2030), endorsed by the World Health Assembly in 2020, is to reduce morbidity and mortality from vaccine-preventable diseases (VPDs) throughout the life-course. (1) [...]

In 2010, the World Health Assembly (WHA) set the following 3 milestones for measles control to be achieved by 2015: 1) increase routine coverage with the first dose of measles-containing [...]

In 2010, the World Health Assembly (WHA) set 3 milestones for measles control, to be achieved by 2015: 1) increase routine coverage with the first dose of measles-containing vaccine (MCV1) [...]

The Global Vaccine Action Plan 2011-2020 (GVAP), (1) endorsed by the World Health Assembly in 2012, calls on all countries to reach [greater than or equal to]90% national coverage with [...]

In 2010, the World Health Assembly set 3 milestones for measles prevention to be achieved by 2015: 1) increase routine coverage with the first dose of measles-containing vaccine (MCV1) among [...]

The Global Vaccine Action Plan (GVAP) (1) 2011-2020, endorsed by the World Health Assembly in 2012, calls on all countries to reach >90% national coverage for all vaccines in the [...]

Infections due to hepatitis B virus (HBV) are a leading cause of death worldwide. WHO estimated that in 2015, 257 million people globally were living with chronic HBV infection and [...]

Endorsed by the World Health Assembly in 2012, the Global Vaccine Action Plan 2011-2020 (GVAP) (1) calls on all countries to reach [greater than or equal to] 90% national coverage [...]

In 1974, WHO established the Expanded Programme on Immunization (EPI) to ensure that all children have access to 4 routinely recommended vaccines: (1) Bacille Calmette-Guerin vaccine (BCG) for protection against [...]

In 2000, the UN General Assembly adopted the Millennium Development Goals (MDG), with MDG4 being a reduction of two thirds in child mortality by 2015, and with measles vaccination coverage [...]

In 1974, WHO established the Expanded Programme on Immunization to ensure that all children have access to routinely recommended vaccines. (1) Since then, global coverage with the 4 core vaccines--Bacille [...]

Rubella virus usually causes a mild fever and rash in children and adults; however, infection during pregnancy, especially during the first trimester, can result in miscarriage, fetal death, stillbirth, or [...]

The article presents a report from the World Health Organization (WHO) on COVID-19 mortality and progress toward vaccinating older adults from 2020-2022. Topics discussed include impact of COVID-19 during the period, reported and estimated excess COVID-19-associated deaths, and ratio of excess COVID-19 mortality estimates to aggregate number of reported deaths.