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The 235U(n,f) cross section was measured in a wide energy range (25 meV - 170 keV) at the n_TOF facility at CERN, relative to 6Li(n,t) and 10B(n,alpha) standard reactions, with high resolution and accuracy, with a setup based on a stack of six samples and six silicon detectors placed in the neutron beam. In this paper we report on the results in the region between thermal and 10 keV neutron energy. A resonance analysis has been performed up to 200 eV, with the code SAMMY. The resulting fission kernels are compared with the ones extracted on the basis of the resonance parameters of the most recent major evaluated data libraries. A comparison of the n_TOF data with the evaluated cross sections is also performed from thermal to 10 keV neutron energy for the energy-averaged cross section in energy groups of suitably chosen width. A good agreement is found in average between the new results and the latest evaluated data files ENDF-B/VIII and JEFF-3.3, as well as with respect to the IAEA reference files. However, some discrepancies are still present in some specific energy regions. The new dataset here presented, characterized by unprecedented resolution and accuracy, can help improving the evaluations in the Resolved Resonance Region and up to 10 keV, and reduce the uncertainties that affect this region.

Background The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting. Methods Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed to compare patient outcomes across groups. Results Of 2232 oesophagectomies from 137 centres in 41 countries, trainees were involved in 29.1 per cent of them (n = 650), performing only the abdominal phase in 230, only the chest and/or neck phases in 130, and all phases in 315 procedures. For procedures with a chest anastomosis, those with trainee involvement had similar 90-day mortality, complication and reoperation rates to consultant-performed oesophagectomies (P = 0.451, P = 0.318, and P = 0.382, respectively), while anastomotic leak rates were significantly lower in the trainee groups (P = 0.030). Procedures with a neck anastomosis had equivalent complication, anastomotic leak, and reoperation rates (P = 0.150, P = 0.430, and P = 0.632, respectively) in trainee-involved versus consultant-performed oesophagectomies, with significantly lower 90-day mortality in the trainee groups (P = 0.005). Conclusion Trainee involvement was not found to be associated with significantly inferior postoperative outcomes for selected patients undergoing oesophagectomy. The results support continued supervised trainee involvement in oesophageal cancer surgery., The aim of this study was to determine the impact of trainee involvement in oesophagectomy on perioperative outcomes in the international multicentre Oesophago-Gastric Anastomosis Audit (OGAA). Analysis of 2232 oesophagectomies has shown that trainee involvement did not negatively impact perioperative outcomes.

Background Textbook outcome has been proposed as a tool for the assessment of oncological surgical care. However, an international assessment in patients undergoing oesophagectomy for oesophageal cancer has not been reported. This study aimed to assess textbook outcome in an international setting. Methods Patients undergoing curative resection for oesophageal cancer were identified from the international Oesophagogastric Anastomosis Audit (OGAA) from April 2018 to December 2018. Textbook outcome was defined as the percentage of patients who underwent a complete tumour resection with at least 15 lymph nodes in the resected specimen and an uneventful postoperative course, without hospital readmission. A multivariable binary logistic regression model was used to identify factors independently associated with textbook outcome, and results are presented as odds ratio (OR) and 95 per cent confidence intervals (95 per cent c.i.). Results Of 2159 patients with oesophageal cancer, 39.7 per cent achieved a textbook outcome. The outcome parameter ‘no major postoperative complication’ had the greatest negative impact on a textbook outcome for patients with oesophageal cancer, compared to other textbook outcome parameters. Multivariable analysis identified male gender and increasing Charlson comorbidity index with a significantly lower likelihood of textbook outcome. Presence of 24-hour on-call rota for oesophageal surgeons (OR 2.05, 95 per cent c.i. 1.30 to 3.22; P = 0.002) and radiology (OR 1.54, 95 per cent c.i. 1.05 to 2.24; P = 0.027), total minimally invasive oesophagectomies (OR 1.63, 95 per cent c.i. 1.27 to 2.08; P < 0.001), and chest anastomosis above azygous (OR 2.17, 95 per cent c.i. 1.58 to 2.98; P < 0.001) were independently associated with a significantly increased likelihood of textbook outcome. Conclusion Textbook outcome is achieved in less than 40 per cent of patients having oesophagectomy for cancer. Improvements in centralization, hospital resources, access to minimal access surgery, and adoption of newer techniques for improving lymph node yield could improve textbook outcome.

Resumen La enfermedad hemol��tica del reci��n nacido, es una afecci��n caracterizada por la destrucci��n masiva de gl��bulos rojos fetales, durante y despu��s del embarazo. Esto se da por incompatibilidad sangu��nea entre la madre y el feto [1]. Esta incompatibilidad se basa en las diferencias antig��nicas entre los diferentes grupos sangu��neos. En el caso de la anemia hemol��tica, la inmunizaci��n ocurre cuando la sangre entre madre y hijo entran en contacto y son de grupos incompatibles entre si. Esto puede ocurrir durante el primer embarazo, cuando la sangre del feto atraviesa la placenta, entrando al torrente sangu��neo de la madre, activando as�� una respuesta inmune dirigida a los gl��bulos rojos del bebe. La destrucci��n masiva de gl��bulos rojos resulta en una gran cantidad de hemoglobina (Hb) liberada al plasma sangu��neo, la cual puede degradarse en bilirrubina, que en condiciones normales ser��a metabolizada por h��gado y excretada por las heces. Pero en el caso de un beb��, con un h��gado inmaduro, la excreci��n de bilirrubina no puede ocurrir, lo que provoca que esta se acumule en el organismo, resultando en hiperbilirrubinemia notoria por provocar neurotoxicidad e ictericia [2]. En el estudio expuesto se busc�� probar que un diagn��stico temprano de la anemia hemol��tica de reci��n nacido por medio de tamizajes de bilirrubina s��rica, pod��an resultar en un tiempo intrahospitalario menor, al poder comenzar el tratamiento antes de que la afecci��n se complique. Al empezar antes el tratamiento, la concentraci��n de bilirrubina s��rica no habr�� aumentado tanto de forma que el tiempo de fototerapia necesaria se reducir��, de igual manera la necesidad de utilizar tratamientos m��s invasivos como la exanguinotransfusi��n se reduce dr��sticamente [1, 3]., {"references":["Lewis, V. V. (2018). Impacto en el diagnóstico temprano de la enfermedad hemolítica del recién nacido en neonatos mayores de 2 kg mediante el tamizaje de la bilirrubinas por método transcutáneo. Revista Pediátrica de Panamá, 20-31.","Yandún, J. T., Flores, P. S., Neira, F. C., Jiménez, J. T., & Vega, L. P. (2011). Enfermedad Hemolítica por Incompatibilidad ABO. Revista Médica HJCA, 3(1), 68-68.","Villegas Cruz, D., Durán Menéndez, R., Alfonso Dávila, A., López De Roux, M. del R., Cortina, L., Vilar Carro, M., & Orbeal Aldama, L. (2007). Enfermedad hemolítica del recién nacido por incompatibilidad ABO. Revista Cubana de Pediatría, 79(4), 0-0."]}

Key to Crotalaria rosenii and two subspecies of Crotalaria agatiflora cultivated 1. Bracteoles to 3 mm wide, flowers 4.5���5.0 cm long, standard 5.0���5.5 �� 4.0��� 4.6 cm, standard callosities glabrous, keel apex hooked.................................................................................................................................................................................. C. rosenii - Bracteoles to 1 mm wide, flowers 3.0��� 3.5 cm long, standard 3.5���3.7 �� 2���3 cm, standard callosities pubescent, keel apex straight.............................................................................................................................................................................................................2 2. Bracteoles to 3 mm long, leaves glabrous or puberulous beneath, leaves elliptic-lanceolate, with 9���12 pairs of secondary veins................................................................................................................................................................ C. agatiflora subsp. agatiflora - Bracteoles of 6���10 mm long, leaves pubescent beneath, leaves ovate-elliptic, with 14���17 pairs of secondary veins.......................................................................................................................................................................................... C. agatiflora subsp. engleri, Published as part of Fonseca-Cort��s, Andr��s, 2022, Misidentified For More Than 50 Years, Crotalaria Rosenii (Leguminosae, Papilionoideae, Crotalarieae), A Cultivated Species In Colombia And Ecuador, pp. 287-297 in Phytotaxa 533 (5) on page 294, DOI: 10.11646/phytotaxa.533.5.4, http://zenodo.org/record/6145174

Polycarpon tetraphyllum (Linnaeus) Linnaeus (1759: 881) subsp. tetraphyllum ��� Mollugo tetraphylla Linnaeus (1753: 89). Type: &horbar; Habitat in Italiae, Narbonae vineis [lectotype designated by Burtt & Lewis (1952): BM catalogue number BM000557701!, image available at https://data.nhm.ac.uk/object/23e95e56-b6b2-47eb-b410-fab483fb1ebc/1642291200000]. Description (Fig. 1):&horbar;Prostrate herbs, with a long principal root, branches bifurcate, internodes 4���10 mm long, glabrous. Stipules 2���4 �� 1���2 mm, two in each node, interpetiolar, triangular-deltoid or lanceolate, scarious, glabrous. Leaves 4���8 �� 2���5 mm, opposite or verticillate, orbicular, ovate or slightly obovate, glabrous, bases attenuated, apices rounded or mucronate, pinnate nerviation with 2���4 pairs of secondary nerves; petiole ca. 1 mm, glabrous. Inflorescence up to 2 cm, terminal, cymose with numerous bracts in the nodes; similar to the stipules. Flowers 2���3 mm, pedicel ca. 1 mm, sepals five, 1���2 �� 1���2 mm, subulate, margins hyaline; petaloid staminodes five, to 1 �� 1 mm, oblong, with apex entire or slightly emarginate, white, shorter than the sepals; stamens 3���5, ca. 1 mm long, white; filaments to 0.6 mm long; anthers 0.2���0.3 mm long; ovoid, dorsifixed; ovary 1���2 mm, superous, ovoid; stile to 1 mm; stigma trifid. Fruit to 3 �� 3 mm, capsule, with three valves. Seeds to 0.5 �� 0.3 mm, semicircular, numerous; testa papillose. Distribution and habitat: &horbar; Polycarpon tetraphyllum is native to the mediterranean and it has spread in America, Africa, Asia, Europe and Oceania (CABI, 2021). In Colombia this species has only been collected in two localities of Bogot�� D.C (Fig. 2). Notes: &horbar; Polycarpon apurese, which is currently the only native Polycarpon taxon occurring in Colombia, is naturally distributed in South America (Argentina, Brazil, Colombia, Paraguay, Uruguay, and Venezuela; Bernal 2016, Mu��oz-Schick et al. 2016, POWO, 2019), whereas it has been introduced in Mexico (Escamilla 1999). Despite not included in the molecular analyses by Kool et al. (2007), P. apurense shows, in our opinion, all the characters typical of P. prostratum and three Macaronesian species of the genus Polycarpaea (Volponi 2004, Kool et al. 2007): P. nivea (Aiton 1789: 286) Webb (in Hooker 1849: 104), P. latifolia Poiret (in Lamarck & Poiret 1816: 473), and P. divaricata Poiret ex Steudel (in Steudel 1841: 369). As a consequence, it is likely that P. apurense is part of this group. P. apurense differs from P. tetraphyllum s.str. being more pubescent, leaves linear to lanceolate, ellipsoidal reticulate brown to reddish seeds with little spines in the dorsal margin, while P. tetraphyllum s.str. is glabrous, the leaves are ovate or obovate, D-shaped papillate white to yellowish seeds unarmed in the dorsal margin. Examined material: &horbar; Polycarpon tetraphyllum subsp. tetraphyllum. COLOMBIA. Cundinamarca: Bogot�� D. C., Engativ��, Cortijo, cll 81 # 114-50, conjunto residencial Parques de Alejandr��a, 4��43���27.3���N 74��07���07.3���W, 2600 m, 20 March 2021, Fonseca-Cort��s 1362 (UDBC); Engativ��, Bochica, 4��43���04.7���N 74��06���52.2���W, 2600 m, 10 April 2021, Fonseca-Cort��s 1758 (UDBC)., Published as part of Fonseca-Cort��s, Andr��s & Sandoval-Ortega, Manuel Higinio, 2022, Polycarpon tetraphyllum (Caryophyllaceae) a new record for the Colombian flora and a key to the genera of the Caryophyllaceae from Colombia, pp. 105-110 in Phytotaxa 533 (1) on pages 106-108, DOI: 10.11646/phytotaxa.533.1.8, http://zenodo.org/record/5974057, {"references":["Linnaeus, C. (1759) Systema naturae, ed. 10, vol. 2. Salvius, Stockholm, 559 pp.","Linnaeus, C. (1753) Species plantarum, vol. 1. Salvius, Stockholm, 560 pp.","Burtt, B. L. & Lewis, P. (1952) On the Flora of Kuweit: II. Kew Bulletin 7 (3): 333 - 352.","CABI (2021) Polycarpon tetraphyllum (fourleaf allseed). CAB International, Wallford. Available from: https: // www. cabi. org / isc / datasheet / 116427 tosummaryOfInvasiveness (accessed 16 January 2022)","Bernal, R. (2016) Cayophyllaceae. In: Bernal, R., Gradstein, S. R. & Celis, M. (Eds.) Catalogo de plantas y liquenes de Colombia. Instituto de Ciencias Naturales, Universidad Nacional de Colombia, Bogota, pp. 1043 - 1046.","Munoz-Schick, M., Moreira-Munoz, A. & de Trenqualye, A. (2016) Polycarpon moreiranum, nueva especie de Caryophyllaceae endemica de Chile. Gayana Botanica 73 (2): 467 - 470. https: // doi. org / 10.4067 / S 0717 - 66432016000200467","POWO (2019) Plants of the World Online. Royal Botanic Gardens, Kew. Available from: http: // www. plantsoftheworldonline. org / (accessed 16 January 2022).","Escamilla, M. (1999) Nuevos registros de Caryophyllaceae para Mexico. Polibotanica 10: 123 - 126.","Kool, A., Bengtson, A. & Thulin, M. (2007) Polyphyly of Polycarpon (Caryophyllaceae) inferred from DNA sequence data. Taxon 56 (3): 775 - 782. https: // doi. org / 10.2307 / 25065860","Volponi, C. R. (2004) Espermatologia y palinologia de las especies de Polycarpon (Caryophyllaceae) en la Argentina. Physis (Buenos Aires), Seccion C 59 (136 - 137): 1 - 9.","Aiton, W. (1789) Hortus Kewensis, vol. 1. Printed for George Nicol, Bookseller to his Majesty, London, 496 pp. https: // doi. org / 10.5962 / bhl. title. 4504","Hooker, W. J. (1849) Niger flora. H. Bailliere, London, 587 pp. https: // doi. org / 10.5962 / bhl. title. 594","Lamarck, J. & Poiret, J. L. M. (1816) Encyclopeidie meithodique. Botanique. Supplement, Tome 4. Madame veuve Agasse imprimeurlibraire, Paris, 731 pp. https: // doi. org / 10.5962 / bhl. title. 826","Steudel, E. T. (1841) Nomenclator botanicus, seu, Synonymia plantarum universalis, Editio secunda, Pars II. Typis et sumptibus J. E. Cottae, Tubinga, 810 pp."]}

Full waveform inversion (FWI) is one of a family of methods that allows the reconstruction of earth subsurface parameters from measurements of waves at or near the surface. This is a numerical optimization problem that uses the whole waveform information of all arrivals to update the subsurface parameters that govern seismic wave propagation. We apply FWI in the multi-scale approach on two well-known benchmarks: Marmousi and 2004 BP velocity model. For the forward modeling, we use an RBF-FD solver on hexagonal grids and quasi-optimal shape parameters., Short report. 9 pages, 2 figures and one table

We classify all left-invariant pseudo-Riemannian Einstein metrics on $\mathrm{SL}(2,\mathbb{R})\times \mathrm{SL}(2,\mathbb{R})$ that are bi-invariant under a one-parameter subgroup. We find that there are precisely two such metrics up to homothety, the Killing form and a nearly pseudo-K\"ahler metric., Comment: 14 pages

Additional file 1. Including information about the schedule and the exact wording of the SMS messages by type of treatment, MedDRA coding of pre-specified events, reasons declared by the patients for attendance to a hospital or health unit during treatment, checklist of symptoms of acute haemolytic anaemia and diagram of the multicomponent strategy implementation.

Supplemental material, sj-docx-1-taj-10.1177_20406223221078091 for Impact of lack of face-to-face schooling during COVID-19 confinement on family quality of life of children with disabilities and typical development by Roc��o Palomo-Carri��n, Rita-Pilar Romero-Galisteo, Helena Romay-Barrero, Mar��a-Dolores Cort��s-Vega, Mar��a-Jes��s Casuso-Holgado and Elena Pinero-Pinto in Therapeutic Advances in Chronic Disease

Additional file 1: Table 1. Clinical manifestations and laboratory abnormalities.

In the present thesis an excitation signal spectrum for the slow extraction is proposed. The spectrum covers two main regions of interest: one that excites particles with low transversal oscillation amplitudes in the beam and one that excites particles with higher amplitude oscillations. The implementation of the signal together with the feedback loop for the control of the amplitude of the excitation improves the median-quality of the extracted particle count (spill) from 92.5% to better than 97.5% for the most rigid carbon-ion beam available. The improvement is more drastic for the proton beam where the quality of the spill can go as poor as 60% and is brought to better than 90% for all extraction energy configurations. The same quality gain is observed for helium- and oxygen-ion beams. The positive effect of the proposed spectrum on the spill quality can be explained from the tune-spread characteristics given by the non-linear dynamics that govern the system. These were mainly studied experimentally through a beam transfer function (BTF) measurement and with particle tracking simulations. Both give an insight into the tune-distribution of the beam under extraction conditions.

The European Virtual Observatory (VO) initiative organises regular VO schools since 2008. The goals are twofold: i) to expose early-career European astronomers to the variety of currently available VO tools and services so that they can use them efficiently for their own research and; ii) to gather their feedback on the VO tools and services and the school itself. During the schools, VO experts guide participants on the usage of the tools through a series of predefined real science cases, an activity that took most of the allocated time. Participants also have the opportunity to develop their own science cases under the guidance of VO tutors. These schools have demonstrated to be very useful for students, since they declare to regularly use the VO tools in their research afterwards, and for us, since we have first hand information about the user needs. Here, we introduce our VO schools, the approach we follow, and present the training materials that we have developed along the years., Proceeding to Astronomy. Software. Systems. ADASS XXXI Conference

Introdu??o: a obesidade e a doen?a hep?tica gordurosa n?o alco?lica (DHGNA) causam preju?zos ? sa?de, interferem na qualidade de vida do indiv?duo e acarretam custos elevados para o sistema p?blico de sa?de. A gordura visceral est? intimamente relacionada ao desenvolvimento de uma mir?ade de anormalidades metab?licas e est? associado ? DHGNA. Objetivo: investigar a associa??o entre a ?rea de gordura visceral e a doen?a hep?tica gordurosa n?o alco?lica em pacientes com obesidade. M?todo: estudo transversal com coleta de dados retrospectiva. A amostra foi composta por pacientes com obesidade, de ambos os sexos, maiores de 18 anos, candidatos ? cirurgia bari?trica entre julho de 2015 a julho de 2017 no COM/HSL/PUCRS. Foram avaliados dados antropom?tricos e a ?rea de gordura visceral atrav?s da bioimped?ncia multi-frequencial. As vari?veis tabagismo e comorbidades tamb?m foram analisadas. A DHGNA foi avaliada por bi?psia hep?tica. O n?vel de signific?ncia adotado foi de 5% (p?0,05) e as an?lises estat?sticas foram realizadas pelo programa SPSS vers?o 21.0. O estudo foi aprovado pelo Comit? de ?tica em Pesquisa da PUCRS sob CAAE 51992321.0.0000.5336. Resultados: Foram inclu?dos 369 participantes, a maioria mulheres (79,4%), com m?dia de idade de 39,2 ? 10,6 anos e IMC m?dio de 45?7,1 kg/m?. N?o foi encontrada associa??o estatisticamente significativa com a DHGNA. Houve associa??o positiva (p

El trabajo se desarrolla con el objetivo de evaluar el efecto del aditivo Pentomuls en las propiedaes f��sicas de mezclas con petr��leo crudo cubano y se realiza en el laboratorio de aceites y lubricantes del grupo de generaci��n Camag��ey I de la Empresa de Mantenimiento a Grupos Electr��genos Fuel Oil. Se parte de la dosificaci��n establecida por el fabricante y se preparan mezclas con cinco concentraciones por encima y por debajo de la especificada. Se determinan el efecto en las propiedades fisicas densidad, viscosidad, asfaltenos, gravedad espec��fica y carb��n Conradson, utilizando las normas ASTM. Los resultados muestran que existe una gran influencia del aditivo en la reducc��n considerable del contenido de asfaltenos desde 31,3167 % m/m en el crudo puro hasta 21,1107 % m/m en la mezcla con la mayor concentraci��n de Pentomuls. En cuanto a la viscosidad din��mica y cinem��tica, estas disminuyen hasta valores minimos cerca de la concentraci��n establecidad por el fabricante (1357,9 mm2/s y 1348 mPa*s, respectivamente) y, para valores m��s altos de concentraci��n, aumenta. La densidad y los grados API no se ven afectados por la concentracion de aditivo, variando entre 992,9 ��� 994,4 kg/m3 y 10,8 ��� 11 ��API, respectivamente. Palabras claves: petr��leo, Pentomuls, propiedades f��sicas, propiedades qu��micas

El art��culo la psicomotricidad en la ense��anza de los gestos motores especializados de la Nataci��n Art��stica, se dirige a develar el empleo de la psicomotricidad en la ense��anza de los gestos motores en la etapa de iniciaci��n las cuales condicionan los m��todos y medios que deber��n desarrollar las habilidades motivo de evaluaci��n en el ejercicio competitivo de rutinas. De esta forma fueron determinadas las tareas que permiten a estas profesionales actuar en aras de transformar desde el contexto donde desempe��an su labor dado el inter��s por la expresividad y representaciones de temas musicales, teatrales, literarios y danzarios en esta modalidad deportiva como elemento de la preparaci��n t��cnico-coreogr��fica desde la iniciaci��n para lo cual es necesario trabajar tanto gestos t��cnicos especializados como la expresi��n extraverbal propiamente dicha. En la actualidad, la Nataci��n Art��stica en todas sus modalidades de rutinas utiliza muchos recursos art��sticos para la interpretaci��n de la tem��tica seleccionada, lo cual ha estimulado la visi��n m��s contempor��nea de este deporte, por ello es necesario vincular las manifestaciones art��sticas con esta pr��ctica deportiva desde la ense��anza de elementos t��cnicos con las exigencias para su correcta ejecuci��n, en relaci��n con la armonizaci��n entre las ejecuciones y la complejidad en el aprendizaje. En este sentido la entrenadora deber�� ser capaz de crear un ambiente tangible donde prime a partir de la instrucci��n, la ense��anza de elementos t��cnicos y art��sticos que permitan alcanzar y manifestar ejecuciones bellas y correctamente realizadas, a partir del montaje de coreograf��as novedosas.

El objetivo del trabajo es socializar los resultados en la innovaci��n de la gesti��n de un programa de maestr��a en tiempos de COVID-19. Responde a las interrogantes: ��Qu�� escenario impone la COVID ��� 19 a la Maestr��a en direcci��n de la Universidad Tecnol��gica Militar ���Jos�� Mart�����, ��Qu�� fortalezas y debilidades encuentra? ��Qu�� acciones dan respuesta a la gesti��n del Gobierno en relaci��n con la innovaci��n en la maestr��a? ��Qu�� resultados y experiencias se obtienen? ��D��nde se aplican, cu��l es el nivel de generalizaci��n? M��todos te��rico: hist��rico l��gico, emp��rico: medici��n. Contribuye en el posgrado con aportes te��ricos: conceptos de innovaci��n, principios, fortalezas, debilidades, Aporte pr��ctico: acciones de innovaci��n en el nuevo escenario (herramientas metodol��gicas), algoritmo, sugerencias de investigaciones que fundamenten cient��ficamente los cambios, transformaciones y procedimientos del posgrado en la emergencia sanitaria y experiencias. Lugar de aplicaci��n durante la pandemia: Maestr��a en direcci��n con estudiantes extranjeros (sexta edici��n concluida) con resultados excelentes y en la s��ptima con estudiantes cubanos (en ejecuci��n) con resultados parciales alentadores. Significaci��n te��rica, metodol��gica y pr��ctica del trabajo: Responde a los acuerdos y resoluciones del 8vo Congreso del Partido sobre la necesidad de asumir la pol��tica de innovaci��n en la educaci��n, en este caso, en el posgrado, a la Resoluci��n 140/19, la INSTRUCCI��N 01/2020 del MES, al Manual para la Gesti��n del Posgrado y el Reglamento de la Junta de Acreditaci��n Nacional (JAN), 2020.

La pandemia no ha impedido continuar la gesti��n de la calidad de los procesos sustantivos universitarios. El objetivo del trabajo consiste en mostrar resultados del trabajo a distancia del Programa de Maestr��a en Direcci��n del Proceso Docente Educativo en la UTM, orientado a desarrollar habilidades directivas e investigativas en dirigentes docentes de universidades militares cubanas y extranjeras. Desde 2008 se han ejecutado seis ediciones, seg��n el programa que ostenta la categor��a de certificado desde 2017. La sexta edici��n de modalidad a tiempo completo desarroll�� los ��ltimos seis meses a distancia, con la defensa de tesis de modo presencial. La s��ptima edici��n, de modalidad parcial, se ejecuta a distancia desde febrero de 2021. Durante el per��odo de distanciamiento social se ha continuado la gesti��n de los procesos sustantivos, no solo como soluciones coyunturales, sino con car��cter permanente y sostenible como resultados de investigaciones realizadas que se concretan en: 1. Dos libros: 1) Sobre la direcci��n del desempe��o de los tutores, contenido socializado previamente en ponencias, art��culos y defendido en tesis de la 6ta. edici��n.2) Sistematizaci��n de resultados y rese��a de investigaciones. Per��odo 2008-2020. 2. Cuatro compilaciones de trabajos del claustro y egresados en apoyo a los cursos, con gu��as de actividades te��rico-pr��cticas. 3. Perfeccionamiento del montaje de las diferentes modalidades de ejecuci��n del Programa. El efecto de los resultados se expresan en la mejora de las variables recursos humanos, investigaci��n y posgrado, infraestructura e impacto social del sistema de evaluaci��n IES y sus indicadores.

Resumen: La b��squeda y el desarrollo de una tecnolog��a de educaci��n avanzada es una necesidad imperiosa que responde a la exigencia de encontrar y proporcionar a la ense��anza una base m��s cient��fica y de hacer, al mismo tiempo, m��s productiva la educaci��n, con un gran ��nfasis en el saber hacer, pero siempre sobre la base de una adecuada dosificaci��n y programaci��n de la ense��anza, o sea, sobre la base de una ense��anza cient��fica. La emergencia sanitaria generada por la Covid-19 ha impulsado a buscar nuevas din��micas dentro de la UPIBI y con ello la mejora continua para la impartici��n de los cursos en la academia de Ingenier��a Biom��dica y por ende la b��squeda de una alternativa para la mejora de las unidades de aprendizaje que conlleven a lograr un perfil de egreso adecuado a las necesidades de las empresas empleadoras, consiguiendo que los indicadores solicitados por los organismos acreditadores de Instituciones de Educaci��n Superior encuentren un plan de estudios de calidad y pertinente en el sector laboral. Es as�� que se propone encontrar los indicadores para realizar la transici��n a una educaci��n a distancia para complementar la labor docente de revisi��n, comunicaci��n y apoyo para dar seguimiento a la labor de ense��anza-aprendizaje. Y ahora realizar actividades de manera as��ncrona, lo que dar�� pauta a que se integren otros estudiantes, quienes por las situaciones particulares no pueden asistir al aula. Pero antes de esto, capacitar al docente con las habilidades que lo llevar��n a un mejor desempe��o en sus actividades cotidianas.

El objetivo del trabajo es presentar un proyecto de investigaci��n que tiene la intenci��n de caracterizar la utilizaci��n del lenguaje matem��tico en los recursos digitales para la ense��anza-aprendizaje de la Aritm��tica de 3er grado de escuelas oficiales de Panam��, para identificar los sesgos did��cticos que contienen y crear el modelo did��ctico que sustente la valoraci��n de los recursos did��cticos en relaci��n con el tema objeto de estudio. La investigaci��n tendr�� como referente te��rico la teor��a hist��rico-cultural fundada por L. S. Vigotsky referida a la relaci��n entre lenguaje, desarrollo y aprendizaje.

La vida en el planeta Tierra, en sus diversas manifestaciones est�� cada vez m��s amenazada a la extinci��n por causas naturales y por el impacto antropog��nico en el medio ambiente, por lo que se impone promover el conocimiento de la diversidad biol��gica en las presentes y futuras generaciones para que puedan actuar responsablemente contribuyendo a su conservaci��n y uso sostenible ante los efectos negativos que ocasiona el cambio clim��tico. En el presente trabajo se aborda la manera en que el colectivo de la disciplina Zoolog��a General de la Carrera Licenciatura en Educaci��n. Biolog��a del Departamento de Biolog��a y Geograf��a de la Universidad de Oriente, se est��n aplicando de forma intencionada un conjunto de acciones did��ctico-metodol��gicas dirigidas a perfeccionar las formas en que se le da tratamiento a los contenidos de biodiversidad, que deben tenerse en cuenta por los profesores de las asignaturas para desarrollar el proceso de ense��anza-aprendizaje en el tercer a��o de la carrera. Se emplearon m��todos del nivel te��rico y emp��rico que permitieron determinar el conocimiento de la diversidad biol��gica y del cambio clim��tico por los estudiantes, corrobor��ndose el poco dominio de los mismos y de las acciones que deben realizar para su conservaci��n y uso sostenible ante los efectos del cambio clim��tico en la actualidad. El aporte del trabajo radica en la propuesta de acciones did��ctico-metodol��gicas para perfeccionar las formas en que se le da tratamiento a los contenidos de biodiversidad en las asignaturas zool��gicas. Palabras claves: Zoolog��a, Conservaci��n, Cambio Clim��tico, Diversidad Biol��gica

El trabajo se desarrrolla en el eje convectivo del generador de vapor de la unidad 6 de la Central Termoel��ctrica 10 de octubre de Nuevitas, con el objetivo de obtener los modelos del calor te��rico transferido, utilizando t��cnicas de inteligencia artificial (redes neuronales profundas). Se identifican las variables tecnol��gicas de entrada al horno del generador de vapor, tanto las de operaci��n como las relativas a las caracter��sticas f��sico qu��micas del combustible, que tienen incidencia en el proceso de transferencia de calor. El modelo obtenido es comparado con el calor real absorvido en cada superficie, obtenido a trav��s de los balances de masa y energ��a para determinar el nivel de ajuste del modelo, obteniendo un valor de un 97%. A partir de estos resultados, se puede determinar el coeficiente de factor de limpieza de cada una de las superficies de transferencia de calor, pasos definitorios para proponer un sistemna inteligente de limpieza de estas superficies. Se presentan las curvas de cada uno de los modelos. Palabras claves: petr��leo, inteligencia artificial, factor de limpieza

La maltina es una bebida alimenticia carente de alcohol, muy demandada en la actualidad debido a su elevado contenido nutritivo. En el presente trabajo se efectu�� la simulaci��n de una planta de producci��n de maltina a escala piloto (150 L/lote), empleando sorgo rojo CIAP R-132 como materia prima principal. Se efectu�� un estudio de sensibilidad consistente en 11 corridas experimentales, mediante el cual se evalu�� la influencia de tres variables de entrada (capacidad de producci��n de maltina por lote; costo de adquisici��n del sorgo rojo; y precio de venta de la botella de maltina) sobre tres indicadores econ��micos de importancia: Valor Actual Neto (VAN), Tasa Interna de Retorno (TIR) y Periodo de Recuperaci��n de la Inversi��n (PRI). Se deben invertir $ 613 000 pesos cubanos (PC) para erigir la planta de producci��n, el costo unitario de producci��n alcanz�� un valor de PC $ 3,73/botella, mientras que se obtuvo un valor de VAN, TIR y PRI de PC $ 3 661 000, 63,20 % y 1,02 a��os, respectivamente, lo cual califica al proceso de econ��micamente rentable y factible desde el punto de vista inversionista. El estudio de sensibilidad permiti�� obtener ecuaciones que establecen la correlaci��n estad��stica existente entre las 3 variables de entrada y las 3 de salida. Se emple�� el simulador SuperPro Designer�� v.8.5 para efectuar la simulaci��n, y el software Statgraphics Centurion XVI�� para el procesamiento estad��stico de los datos. Palabras claves: An��lisis de sensibilidad; maltina; rentabilidad; sorgo; simulaci��n.

Apr��s contr��le complet de toutes les revues du GERFLINT, il est clair que Synergies Alg��rie occupe, et de loin, le tout premier rang de notre Programme mondial de diffusion scientifique francophone en r��seau. Nul besoin d�����tre grand math��maticien pour faire le constat qu���en moyenne, la revue a publi�� annuellement 2 num��ros. C���est une performance compte tenu de l���immensit�� g��ographique du pays. Coordonner un num��ro exige, en effet, la mise en place de relations ��pistolaires complexes entre Annaba et Mostaganem, par exemple, distants de nombreuses centaines de km. Ce sont l�� des consid��rations comptables sur lesquelles il n���y a pas lieu de s���enthousiasmer outre mesure sous r��serve toutefois de tirer de la r��gularit�� des chiffres de pr��cieuses indications d�����valuation., Synergies Alg��rie , n�� 29 / 2021, p. 11-13- Pr��face - GERFLINT https://gerflint.fr/Base/Algerie29/preface.pdf

We explore an idealized theoretical model for the transport of ions within highly asymmetric ionic liquid mixtures. A primitive model (PM)-inspired system serves as a representative for asymmetric ionic materials (such as liquid crystalline salts) which quench to form disordered, partially-arrested phases. Self-Consistent Generalized Langevin Equation (SCGLE) Theory is applied to understand the connection between the size ratio of charge-matched salts and their average mobility. Within this model, we identify novel glassy states where one of the two charged species (either the macro-cation or the micro-anion) are arrested, while the other retains mobility. We discuss how this result is useful in the development of novel single-ion conducting phases in ionic liquid based materials., 11 pages, 5 figures

Editor General Rilton Gon��alo Bonfim Primo | UFBA, Brasil | UH, Cuba | UVA, Espa��a Consejo Editorial Gesilda Meira Lessa | UFBA, Brasil Jos�� F��lix Garc��a Rodr��guez | UJAT, M��xico Marcelo Santana Silva | IFBA, Brasil Maristela do Esp��rito Santo | USNF, Italia Mercedes M��ndez Fari��as | UMG, Cuba Osmara Mu��oz P��rez | UMC, Cuba Renato Villa��a | UETB, Rusia Rilton Gon��alo Bonfim Primo | UFBA, Brasil; UH, Cuba; UVA, Espa��a Sonia Talabante Luis | RETROBA'T, AEDTH, Espa��a Vanessa Ribeiro Simon Cavalcanti | UFBA, Brasil; UP, Portugal Ensayo Fotogr��fico - Feira de S��o Joaquim (Salvador, Bahia, Brasil) Marina Cecilia Espirito Santo Alfaya | UFBA, Brasil, La naturaleza compleja y multidimensional de los problemas ocasionados por la pandemia de COVID 19 representa un reto en materia de investigaci��n. Reto que debe afrontarse desde una perspectiva multi y transdisciplinaria. Este es justamente el prop��sito del libro en compilaci��n que tiene usted en sus manos. En ��ste se conjugan los trabajos de varios investigadores de Am��rica Latina, quienes desde su propia perspectiva disciplinaria presentan los resultados de sus investigaciones en torno al impacto de la pandemia en sus objetos de estudio.

Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to follow. The pathologist looks at the arrangement of cancer cells in the prostate and assigns a score on a scale that ranges from 6 to 10. Automatic analysis of prostate whole-slide images (WSIs) is usually addressed as a binary classification problem, which misses the finer distinction between stages given by the GS. This paper presents a probabilistic deep learning ordinal classification method that can estimate the GS from a prostate WSI. Approaching the problem as an ordinal regression task using a differentiable probabilistic model not only improves the interpretability of the results, but also improves the accuracy of the model when compared to conventional deep classification and regression architectures.

Partindo da premissa de que a obra de Pierre Bourdieu ? uma obra que pode contribuir para os desafios do ser humano no s?culo XXI, propomos como investiga??o filos?fica destacar de sua obra a concep??o de ser humano com a qual opera. Embora Bourdieu n?o apresente uma conceitua??o a respeito do ser humano, parte-se do princ?pio de que todo pensador trabalha com concep??es a respeito do ser humano e a respeito do mundo, no caso deste autor, do mundo social. A concep??o de ser humano bourdieusiana ? o objeto de pesquisa elaborado em quatro cap?tulos inter-relacionados. O primeiro cap?tulo parte da premissa que Bourdieu constr?i a concep??o de ser humano como um ser social a partir de sua perspectiva de vida, uma perspectiva voltada para a a??o como categoria relevante na problematiza??o da rela??o indiv?duo e sociedade. Com isso, propomos a reconstru??o da trajet?ria pessoal entrela?ada com a trajet?ria intelectual bourdieusiana a fim de elencar a concep??o de ser humano social. Enquanto ser humano social, propomos apresentar no segundo cap?tulo, o construtivismo bourdieusiano fundamentado na a??o coletiva. Tal proposta questiona a nomenclatura ofertada pelo autor, o estruturalismo construtivista ou construtivismo estruturalista a partir do encontro de Bourdieu com Jean Piaget e Lev S. Vigostki. A partir disso, no terceiro cap?tulo se imp?s como inicialmente necess?rio demonstrar as diferen?as que permitem colocar a n?o pertin?ncia de entender a teoria bourdieusiana como uma teoria estruturalista. A discuss?o ? com a antropologia estruturalista l?vistraussiana com e contra a qual Bourdieu constr?i sua teoria. Ap?s isso, o objetivo ? demonstrar a articula??o dos conceitos de habitus, campo e capital no escopo do construtivismo bourdieusiano a fim de finalizar com a concep??o de ser humano social como agente social assentado na a??o. A proposta doutoral almeja ofertar uma contribui??o ? pesquisa da obra bourdieusiana e ? filosofia contempor?nea. From the premise that Pierre Bourdieu's work can contribute to the challenges of the human being in the 21st century, we propose as a philosophical investigation to highlight the conception of the human being with which he operates from his work. Although Bourdieu does not present a concept about the human being, it is assumed that every thinker works with conceptions about the human being and about the world, in the case of this author, the social world. The Bourdieusian conception of the human being is the object of research elaborated in four interrelated chapters. The first chapter starts from the premise that Bourdieu builds the concept of human being as a social being from his perspective of life, a perspective focused on action as a relevant category in problematizing the relationship between individual and society. With that, we propose the reconstruction of the personal trajectory intertwined with the Bourdieusian intellectual trajectory in order to list the concept of social human being. As a social human being, we propose to present in the second chapter, the Bourdieusian constructivism based on collective action. Such proposal questions the nomenclature offered by the author, the constructivist structuralism or structuralist constructivism from Bourdieu's encounter with Jean Piaget and Lev S. Vigostki. From this, in the third chapter it was imposed as initially necessary to demonstrate the differences that allow to place the irrelevance of understanding Bourdieusian theory as a structuralist theory. The discussion is with the L?vi-straussian structuralist anthropology with and against which Bourdieu constructs his theory. After that, the objective is to demonstrate the articulation of the concepts of habitus, field and capital within the scope of Bourdieusian constructivism. Finally, the fourth chapter is devoted to the conception of a social human being as a social agent based on action. The doctoral proposal aims to offer a contribution to the research of Bourdieusian work and contemporary philosophy.

The electrocaloric (EC) effect is the reversible change in temperature and/or entropy of a material when it is subjected to an adiabatic electric field change. Our tight-binding calculations linked to Fermi statistics, show that the EC effect is sensitive to the stacking arrangement in trilayer graphene (TLG) structures connected to a heat source, and is produced by changes of the electronic density of states (DOS) near the Fermi level when external gate fields are applied on the outer graphene layers. We demonstrate the AAA-stacked TLG presents an inverse EC response (cooling), whereas the EC effect in ABC-stacked TLG remains direct (heating) regardless of the applied gate field potential strength. We reveal otherwise the TLG with Bernal-ABA stacking geometry generates both the inverse and direct EC response in the same sample, associated with a gate-dependent electronic entropy transition at finite temperature. By varying the chemical potential to different Fermi levels, we find maxima and minima of the DOS are located near the extremes of the electronic entropy, which are correlated with sign changes in the differential entropy per particle, giving a particular experimentally measurable electronic entropy spectrum for each TLG geometry. The EC effect in quantum two-dimensional layered systems may bring a wide variety of prototype van der Waals materials that could be used as versatile platforms to controlling the temperature in nanoscale electronic devices required in modern portable on-chip technologies., 11 pages, 10 figures

Additional file 4: Table 1. Statistical analysis of structures observed in IHC over monkey peripheral nerve. Table 2. Statistical comparison between GBS patients with and without anti-ganglioside antibodies.

We prove that if $u:K \rightarrow M$ is a left minimal extension, then there exists an isomorphism between two subrings, $\textrm{End}_R^M(K)$ and $\textrm{End}_R^K(M)$ of $\textrm{End}_R(K)$ and $\textrm{End}_R(M)$ respectively, modulo their Jacobson radicals. This isomorphism is used to deduce properties of the endomorphism ring of $K$ from those of the endomorphism ring of $M$ in certain situations such us when $K$ is invariant under endomorphisms of $M,$ or when $K$ is invariant under automorphisms of $M$.

Most problems in Earth sciences aim to do inferences about the system, where accurate predictions are just a tiny part of the whole problem. Inferences mean understanding variables relations, deriving models that are physically interpretable, that are simple parsimonious, and mathematically tractable. Machine learning models alone are excellent approximators, but very often do not respect the most elementary laws of physics, like mass or energy conservation, so consistency and confidence are compromised. In this paper, we describe the main challenges ahead in the field, and introduce several ways to live in the Physics and machine learning interplay: to encode differential equations from data, constrain data-driven models with physics-priors and dependence constraints, improve parameterizations, emulate physical models, and blend data-driven and process-based models. This is a collective long-term AI agenda towards developing and applying algorithms capable of discovering knowledge in the Earth system., 24 pages, 10 figures, 3 tables, expanded AAAI PGAI 2020 Symposium

This paper tackles the problem of discretizing accelerated optimization flows while retaining their convergence properties. Inspired by the success of resource-aware control in developing efficient closed-loop feedback implementations on digital systems, we view the last sampled state of the system as the resource to be aware of. The resulting variable-stepsize discrete-time algorithms retain by design the desired decrease of the Lyapunov certificate of their continuous-time counterparts. Our algorithm design employs various concepts and techniques from resource-aware control that, in the present context, have interesting parallelisms with the discrete-time implementation of optimization algorithms. These include derivative- and performance-based triggers to monitor the evolution of the Lyapunov function as a way of determining the algorithm stepsize, exploiting sampled information to enhance algorithm performance, and employing high-order holds using more accurate integrators of the original dynamics. Throughout the paper, we illustrate our approach on a newly introduced continuous-time dynamics termed heavy-ball dynamics with displaced gradient, but the ideas proposed here have broad applicability to other globally asymptotically stable flows endowed with a Lyapunov certificate.

In this paper, a multi-modal 360$^{\circ}$ framework for 3D object detection and tracking for autonomous vehicles is presented. The process is divided into four main stages. First, images are fed into a CNN network to obtain instance segmentation of the surrounding road participants. Second, LiDAR-to-image association is performed for the estimated mask proposals. Then, the isolated points of every object are processed by a PointNet ensemble to compute their corresponding 3D bounding boxes and poses. Lastly, a tracking stage based on Unscented Kalman Filter is used to track the agents along time. The solution, based on a novel sensor fusion configuration, provides accurate and reliable road environment detection. A wide variety of tests of the system, deployed in an autonomous vehicle, have successfully assessed the suitability of the proposed perception stack in a real autonomous driving application., Accepted for publication in IEEE ITSC 2020

Pimelodella longibarbata, new species (Figs. 1���4, Table 1) urn:lsid:zoobank.org:act: 9003327E-9205-4685-B21F-B6E8D92FB37A Holotype. IAvH-P 21920, 48.6 mm SL. Venezuela, Apure, El Amparo, NN creek, tributary of Ca��o Verde, 07��06���33.3���N 70��41���26.3���W, 2 Oct 2017, L. M. Mesa-Salazar. O. E. Castillo-G, J. M. Qui��ones-Montiel. Paratypes. Venezuela: IAvH-P 17879, 2 (48.7���60.3 mm SL), 1 c&s (48.8 mm SL), collected with the holotype. Colombia: IAvH-P 12039, 3 (57.7���71.8 mm SL), Arauca, Arauca, r��o Lipa, 06��46���48.3���N 71��01���20.3���W, L. Ort��z, 10 Mar 2013; IAvH-P 13025, 1 (45.4 mm SL), Arauca, Puerto Rond��n, r��o Cravo, 06��30���26���N 70��45���14.9���W, L. Ort��z, 5 Dec 2014; IAvH-P 17212, 1 (56.9 mm SL), Casanare, Paz de Ariporo, laguna Las Brisas, 05��39���37.4���N 70��55���40.7���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 17 Apr 2016; IAvH-P 17281, 4 (58.8���75.2 mm SL), 1 c&s (60.1 mm SL), Casanare, Paz de Ariporo, Tapa La Guayabera, 05��38���41.4���N 71��13���47.7���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 20 Apr 2016; IAvH-P 17300, 3 (44.5���51.4 mm SL), Casanare, Paz de Ariporo, Tapa El Venado, 05��36���49.5���N 71��05���44.3���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 7 Apr 2016; IAvH-P 17309, 2 (67.9���69.6 mm SL), Casanare, Paz de Ariporo, Tapa Los Hilariones, 05��36���34.4���N 71��11���13.3���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 21 Sep 2016; IAvH-P 17321, 2 (48.7���56.7 mm SL), Casanare, Paz de Ariporo, Tapa El Venado, 05��36���49.5���N 71��05���44.3���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 21 Sep 2016; IAvH-P 17365, 7 (43.9���58.6 mm SL), Casanare, Paz de Ariporo, Tapa Las Matas, 05��39���14.3���N 71��00���31.4���W, A. Urbano-Bonilla & A. M��- ndez-L��pez, 19 Sep 2016; IAvH-P 17389, 3 (32.4���58.6 mm SL), Casanare, Paz de Ariporo, ca��o La Hermosa, 05��42���20.8���N 71��01���11.3���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 23 Sep 2016; IAvH-P 17463, 1 (56.3 mm SL), Casanare, Paz de Ariporo, laguna Las Brisas, 05��39���37.4���N 70��55���40.7���W, A. Urbano-Bonilla & A. M��ndez-L��pez, 24 Sep 2016; IAvH-P 21908, 3 (60.1���61.7 mm SL), Arauca, Arauca, ca��o Primores, 06��47���13.1���N 71��03���47.2���W, L. Ort��z, 12 Mar 2013. Diagnosis. Pimelodella longibarbata differs from all congeners, except P. cruxenti, P. howesi, P. humeralis, P. mucosa, and P. notomelas by having a long maxillary barbel that surpasses the tip of the dorsal lobe of the caudal fin (vs. maxillary barbel reaching between the origin of pelvic fin and the base of caudal fin). The new species is distinguished from P. cruxenti, P. howesi, and P. humeralis by having fewer total vertebrae (40���42 vs. 44 in P. howesi, 47���49 in P. cruxenti and P. humeralis). Additionally, it can be differentiated from P. cruxenti and P. humeralis by having a shorter adipose fin (32.8���36.4% of SL vs. 48.7���51.3% in P. cruxenti; 41.8���45.3% in P. humeralis). Furthermore, P. longibarbata is distinguished from P. humeralis by lacking a dark anteriorly oblique blotch in the humeral region (vs. blotch present), and from P. howesi by having the ventral lobe of the caudal fin longer (vs. dorsal lobe slightly longer). Pimelodella longibarbata is distinguished from P. mucosa by having a longer adipose fin (32.8���36.4% of SL vs. 28.6%), shorter anal fin (8.7���12.0% of SL vs. 13.4%), background body coloration yellowish (vs. brown), faint and narrow midlateral stripe (vs. well-developed and wide midlateral band), and paired dorsal brown stripes absent (vs. present). Pimelodella longibarbata is distinguished from P. notomelas by lacking black pigmentation on distal third of dorsal fin (vs. distal third of dorsal fin dark brown to black). Description. Morphometric data summarized in Table 1. Body elongate, deeper at dorsal-fin origin. Dorsal profile of body rises in a convex curve from snout to above orbit, then straight and upward to dorsal-fin origin, dorsal fin base convex, slightly concave from posterior end of dorsal-fin to adipose-fin origin, slightly convex along adipose-fin base, and concave along caudal peduncle. Ventral profile of body straight to slightly convex from jaw tip to pelvic-fin origin, slightly concave between pelvic-fin and anal-fin origin, anal-fin base straight and upward, and concave along caudal peduncle (Figs. 1���2). Head conical. Mouth subterminal, upper jaw more pronounced than lower jaw. Premaxilla and dentary with five or six rows of villiform teeth. Anterior naris tubular. Posterior naris rounded, slightly closer to anterior ocular margin than to anterior nares, anteromedially bordered by a fleshy margin. Nares disposed in trapezoidal arrangement. Barbels thin and slightly flattened, elliptical in cross section. Maxillary barbel surpassing upper caudal-fin lobe. Outer mental barbel reaching between distal end of pectoral-fin and pelvic-fin origin. Inner mental barbel reaching pectoral-fin base. Eye slightly elliptical, its greatest diameter along horizontal axis, placed dorsolaterally. Limits of eye well-defined by a free orbital rim. Supraoccipital process subrectangular in shape and long, reaching anterior nuchal plate. Branchiostegal membranes almost entirely free, united to isthmus only at medial apex and not joined to each other anteriorly. Branchiostegal rays six. Gill rakers on first gill arch 8���10, 6���7 associated to anterior margin of ceratobranchial, usually one on cartilage between ceratobranchial and epibranchial, and two on epibranchial. Dorsal fin with spinelet, spine and six branched rays (18), originating approximately above posterior end of pseudotympanum. Distal margin of dorsal fin slightly convex. Spinelet large with wide base and rounded distal tip. Dorsal-fin spine straight, slender, pungent, shorter than first branched ray (14.7���18.2% of SL). Anterior margin of dorsal spine with serrae along distal third, posterior margin with serrae along distal third, and small, straight to retrorse dentations along second third of its length. Anteriormost dorsal-fin pterygiophore inserted above complex vertebra; posteriormost dorsal-fin pterygiophore located ahead of neural spine of vertebra 11. Pectoral fin with distal margin slightly convex, with one unbranched and eight* (13) or nine (4) branched rays. First pectoral-fin ray curved with basal portion ossified, forming a spine, and short distal tip flexible and clearly segmented (Fig. 3). Anterior margin of pectoral-fin spine with 20���25 small straight dentations covering two-thirds of margin (except for a smooth ridge near spine base), and 5���8 serrae along its distal third. Posterior margin with 12���18 retrorse dentations along its basal three-quarters (Fig. 3). Pelvic-fin with convex distal border. Pelvic-fin origin at vertical through base of last dorsal-fin ray. Tip of pelvic fin surpassing vertical through adipose-fin origin, but not exceeding first fourth of its base. Pelvic-fin rays i,5 (18), first ray distinctly shorter than second and third rays (first and second branched rays, respectively). Anal-fin margin rounded, with iv,7 (4), 8* (10) or 9 (4) rays. Two or three anteriormost anal-fin rays embedded in thick skin fold. Anal-fin origin behind vertical through first fourth of adipose-fin base. Anal-fin adpressed terminus between verticals through 70 and 80% of adipose-fin base. Tip of anteriormost anal-fin pterygiophore inserted immediately posterior to hemal spine of vertebra 23. Tip of posteriormost anal-fin pterygiophore inserted immediately ahead of hemal spine of vertebra 28. Adipose fin relatively short (32.8���36.4% of SL), forming ascending curve in lateral profile with deepest point approximately at midlength. Distance from dorsal fin to adipose fin less than length of dorsal-fin base. Origin of adipose fin posterior to midlength of trunk, and approximately at vertical through vertebral centrum 18. Adipose-fin terminus at vertical through vertebral centrum 36. Caudal fin deeply forked, ventral caudal-fin lobe longer than dorsal lobe, both lobes with rounded contours. Dorsal lobe with 14 procurrent rays and one unbranched and seven branched principal rays. Ventral lobe with 16 procurrent rays and one unbranched and eight branched principal rays. Seven rays articulated to dorsal caudal-fin plate (five to hypurals 3+4 and two to hypural 5) and eight rays articulated to ventral caudal-fin plate (six to hypurals 1+2 and two to parhypural). Parhypural not fused to hypural 1 (Fig. 4). Hypurals 1 and 2 completely co-ossified into single ventral caudal plate. Hypurals 3 and 4 completely fused to each other. Hypural 5 not fused to hypurals 3+4. Middle caudal-fin ray of dorsal lobe not articulated to caudal plate (Fig. 4). Total vertebrae 40���42 (2). Ribs nine (2). Cephalic laterosensory system with simple (unbranched) canals ending in single pores. Supraorbital canal continuous, connected anteriorly to infraorbital canal (forming complex s2+i2 pore), and posteriorly to the otic canal. Supraorbital canal with seven sensory pores: s1, s2+i2, s3, s4, s6 (epiphyseal branch), s7, and s8 (parietal branch). Contralateral epiphyseal branches fused to each other medially, ending in a single sensory pore (s6+s6). Paratype specimen of 65.0 mm SL (IAvH-P 17879) with unfused paired s6 pores, adjacent to each other at dorsal midline. Infraorbital canal with six sensory pores: i1, s2+i2, i3, i4, i5, and i6. Preoperculomandibular canal with 11 sensory pores, along dentary, subpreopercle and preopercle. Sensory pores of dentary and preopercle wide and corresponding foramina of preoperculomandibular canal large and externally conspicuous. Lateral line canal complete, extending to basal portion of middle caudal-fin rays. Coloration in alcohol. Background body coloration yellowish. Ventral region of head and body lighter. Dorsal surface of head with dense concentration of dark brown chromatophores, more densely clustered delimiting supraorbital canal margins and snout portion of infraorbital canal. A conspicuous paired dark blotch, looking as a cloven hoof on occipital region. Dorsal surface of maxillary barbel darker than ventral surface. Mental barbels yellow. Conspicuous dark humeral blotch. A brown faint and narrow midlateral stripe extending from pseudotympanum, fading posteriorly along caudal peduncle, and ending as a spot at caudal-fin base (Figs. 1���2). Dorsal-fin base darkly pigmented, from spinelet to posterior most interradial membrane (Fig. 2). Adipose, anal, and caudal fins hyaline. Pectoral and pelvic fins with few dark chromatophores sparse along rays and interradial membranes hyaline. Etymology. The specific epithet longibarbata is from the Latin adjectives longus for long and barbata for bearded and refers to the long maxillary barbel. Distribution and habitat. Pimelodella longibarbata is known from piedmont tributaries of the Arauca, Casanare, and Meta River drainages, which are major Andean tributaries of the western Orinoco River basin (Fig. 5). The water physicochemical parameters measured during the collection event of the paratypes are summarized in Table 2., Published as part of Cort��s-Hern��ndez, Miguel ��ngel, Donascimiento, Carlos & Ram��rez-Gil, Hernando, 2020, A new species of Pimelodella Eigenmann & Eigenmann, 1888 (Siluriformes: Heptapteridae) from the Orinoco River basin, pp. 491-506 in Zootaxa 4808 (3) on pages 492-497, DOI: 10.11646/zootaxa.4808.3.5, http://zenodo.org/record/3933719

This report is Deliverable D2.1 of the MAGNITUDE H2020 European project. The objective is to define the MAGNITUDE conceptual technical and commercial functional architectures to maximise the flexibility provision by multi-energy systems, stressing the overall organisational structures and high level simplified business use cases. These architectures and business use cases are then used in other Work Packages of the project, that define more precise use cases descriptions, tailored to their specific needs. Specifying the technical and commercial functional architectures of the project, implies the following activities: Describe the project concepts and high level conceptual architecture. Identify the project business use cases. Analyse the main relevant stakeholders involved in the overall process of flexibility provision by MES, considering the four energy sectors (electricity, gas, heating and cooling). Describe them in terms of their roles and their interactions. Using the roles and interactions, formalize generic conceptual technical and commercial functional architectures in the form of sequence diagrams which allow to describe the organisation of the stakeholders and the flexibility provision mechanisms. More specifically, Chapter 2 describes the MAGNITUDE main concepts and high level conceptual architecture. Chapter 3 is devoted to the identification and characterisation of the high level (simplified) business use cases that are investigated in the project. In Chapter 4, the concept of roles and role models is first introduced, as well as the main roles involved in the electricity, gas, heating and cooling systems, which are relevant for the MAGNITUDE project. The roles currently identified in the 7 case studies of the project for the 4 energy sectors are then described and the main interactions between the identified roles in the current situation are provided in the form of generic sequence diagrams. Chapter 5 describes the proposed interactions between the aggregation platform and the multi-energy systems for the provision of flexibility to the electricity systems and further extends the generic sequence diagram for the electricity system. Chapter 6 is devoted to the description of the roles and the interactions involved in innovative market designs proposed for multi-carrier market integration and hence the enhancement of the synergies at market level. Conclusions and future perspectives are given in Chapter 7. Finally, the appendices of Chapter 9 provide the results of the detailed analysis carried out for each of the 7 real-life case studies in the current situation for the 4 energy sectors considered (electricity, gas, heat and cooling), regarding: the stakeholders involved in the case study, the roles they carry out, the main interactions between these roles in the form of sequence diagrams.

Dacoderus werneri Aalbu, Andrews and Pollock, 2006 This species was previously reported from the state of Morelos, and dubiously from the state of Oaxaca, Mexico (Aalbu et al. 2006). The locality of Tepetlapa, referred to the state of Oaxaca in Aalbu et al. (2006), is located in the state of Guerrero, near the border with the states of Puebla and Oaxaca. In addition, we examined a female specimen labeled: ��� M��XICO: Guerrero, Mochitl��n, Acahuizotla, VI-1986, Alt. 650 m, bosque tropical mediano subcaducifolio, trampa NTP-80, L. Delgado col.��� (IEXA). This specimen has the elytra fused and hind wings absent., Published as part of Delgado, Leonardo, Santiago-Jim��nez, Quiyari J. & Cort��s-Hern��ndez, Kevin Alexis, 2020, A New Species of Myrmecoderus Aalbu, Andrews and Pollock (Coleoptera: Salpingidae: Dacoderinae) from Mexico, with a Key to the Species and Comments on Macroptery in the Genus, pp. 434-437 in The Coleopterists Bulletin 74 (2) on page 437, DOI: 10.1649/0010-065X-74.2.434, http://zenodo.org/record/4836972, {"references":["Aalbu, R. L., F. G. Andrews, and D. A. Pollock. 2006 [2005]. Revision of Western Hemisphere Dacoderinae with a phylogenetic analysis of world taxa (Coleoptera: Salpingidae). Coleopterists Society Monograph 4: 1 - 40."]}

Component reliability and performance pose a great challenge for interconnection networks. Future technology scaling such as transistor integration capacity in VLSI design will result in higher device degradation and manufacture variability. As a consequence, changes in the network arise, often rendering irregular topologies. This paper proposes a topology-agnostic distributed segment-based algorithm able to handle switch discovery in any topology while guaranteeing connectivity among switches. The proposal, known as Transparent Distributed Segment-Based Routing (TDSR), has been applied to meshes with defective link configurations.

We consider an epidemic spreading in a city which is divided geographically into different districts. We introduce the reproduction matrix $\R=\bigl(R(i,j)\bigr)$ between districts, where $R(i,j)$ is the mean number of individuals in district $j$ infected by an individual from district $i$. We analyse policies of partial lockdowns of the city, that is of a set of districts, based on the study of matrix $\R$, where rows and columns corresponding to districts in lockdown are set to zero. This schema can also be applied to a country divided into regions or other appropriate units, provided the relevant information is available. We conclude by analyzing a matrix~$\R$ which was constructed for the spread of COVID-19 in Santiago, Chile, with the aid of an agent-based simulator for generating surrogate district data., 10 pages

Neutron capture cross section measurements on$^{155}$Gd and$^{157}$Gd were performed using the time-of-flight technique at the n_TOF facility at CERN on isotopically enriched samples. The measurements were carried out in the n_TOF experimental area EAR1, at 185 m from the neutron source, with an array of 4 C$_{6}$D$_{6}$ liquid scintillation detectors. At a neutron kinetic energy of 0.0253 eV, capture cross sections of 62.2(2.2) and 239.8(8.4) kilobarn have been derived for$^{155}$Gd and$^{157}$Gd, respectively, with up to 6% deviation relative to values presently reported in nuclear data libraries, but consistent with those values within 1.6 standard deviations. A resonance shape analysis has been performed in the resolved resonance region up to 181 eV and 307 eV, respectively for$^{155}$Gd and$^{157}$Gd, where on average, resonance parameters have been found in good agreement with evaluations. Above these energies and up to 1 keV, the observed resonance-like structure of the cross section has been analysed and characterised. From a statistical analysis of the observed neutron resonances we deduced: neutron strength function of $2.01(28) \times 10^{-4}$ and $2.17(41) \times 10^{-4}$ , average total radiative width of 106.8(14) meV and 101.1(20) meV and s-wave resonance spacing 1.6(2) eV and 4.8(5) eV for n +$^{155}$Gd and n +$^{157}$Gd systems, respectively. Neutron capture cross section measurements on$^{155}$Gd and$^{157}$Gd were performed using the time-of-flight technique at the n_TOF facility at CERN on isotopically enriched samples. The measurements were carried out in the n_TOF experimental area EAR1, at 185 m from the neutron source, with an array of 4 C$_{6}$D$_{6}$ liquid scintillation detectors. At a neutron kinetic energy of 0.0253 eV, capture cross sections of 62.2(2.2) and 239.8(8.4) kilobarn have been derived for$^{155}$Gd and$^{157}$Gd, respectively, with up to 6% deviation relative to values presently reported in nuclear data libraries, but consistent with those values within 1.6 standard deviations. A resonance shape analysis has been performed in the resolved resonance region up to 181 eV and 307 eV, respectively for$^{155}$Gd and$^{157}$Gd, where on average, resonance parameters have been found in good agreement with evaluations. Above these energies and up to 1 keV, the observed resonance-like structure of the cross section has been analysed and characterised. From a statistical analysis of the observed neutron resonances we deduced: neutron strength function of $2.01(28) \times 10^{-4}$ and $2.17(41) \times 10^{-4}$, average total radiative width of 106.8(14) meV and 101.1(20) meV and s-wave resonance spacing 1.6(2) eV and 4.8(5) eV for n +$^{155}$Gd and n +$^{157}$Gd systems, respectively. Neutron capture measurements on $^{155}$Gd and $^{157}$Gd were performed using the time-of-flight technique at the n\_TOF facility at CERN. Four samples in form of self-sustaining metallic discs isotopically enriched in $^{155}$Gd and $^{157}$Gd were used. The measurements were carried out at the experimental area (EAR1) at 185 m from the neutron source, with an array of 4 C$_6$D$_6$ liquid scintillation detectors. The capture cross sections of $^{155}$Gd and $^{157}$Gd at neutron kinetic energy of 0.0253 eV have been estimated to be 62.2(2.2) kb and 239.8(9.3) kb, respectively, thus up to 6\% different relative to the ones reported in the nuclear data libraries. A resonance shape analysis has been performed in the resolved resonance region up to 180 eV and 300 eV, respectively, in average resonance parameters have been found in good agreement with evaluations. Above these energies the observed resonance-like structures in the cross section have been tentatively characterised in terms of resonance energy and area up to 1 keV.

A translational knowledge map of COVID-19, based on the analysis of scientific papers and networks citation concurrence of terms and keywords of the terms: covid- 19, 2019-ncov and sars-cov-2 in leading databases (MEDLINE, web of Science and Scopus), was constructed. Some fields of the research on covid-19 are connected together, differing in structure, content and evolution.

The high consumption of tomatoes worldwide has made them an essential source of health-promoting carotenoids that prevent a variety of chronic degenerative diseases, such as diabetes, high blood pressure, and cardiovascular disease. Tomatoes are available year-round, consumed fresh, and used as a raw material for the production of many processed products, such as juices, pastes, and purees. A plethora of carotenoids has been characterized in tomatoes. Most of the relevant carotenoids in the human bloodstream are supplied by fresh and processed tomatoes. Lycopene is the predominant carotenoid in tomato and tomato-based food products. Other carotenoids such as α-, β-, γ- and ξ-carotene, phytoene, phytofluene, neurosporene, and lutein are present in tomatoes and related products. There is a growing body of evidence that these bioactive compounds possess beneficial properties, namely anticarcinogenic, cardioprotective, and hepatoprotective effects among other health benefits, due to their antioxidant, anti-mutagenic, anti-proliferative, anti-inflammatory, and anti-atherogenic properties. This chapter analyzes the carotenoid composition of tomatoes and their based products as major contributors to the chronic disease-preventive properties.

Non-polymeric microspheres are stable-shaped particles constituted by crystalline organic compounds. This technology allows controlled release of parental products that has its prime value on estrogen therapy. The structure is a non-polymeric crystalline microsphere that uses a low solubility fatty acid, cholesterol as a carrier. Cholesterol is a waxy lipid, a substance that is insoluble in water and has been recognized as safe as excipient by FDA for the manufacturing of drugs. Cholesterol is a lipid present in the cell membrane and subcellular organelles of tissues and serves as the building block for all steroid hormones including cortisol, aldosterone, estrogen, and testosterone; therefore, this fatty acid provides better biocompatibility than polymers. The use of cholesterol as a low solubility carrier was used to develop a first of its kind, parental HT product for the management of menopausal symptoms carrying estrogen microspheres in an aqueous suspension, which would allow an extended estrogen release maintaining plasmatic therapeutic concentrations. Estradiol doses would be up to 30 times lower than that provided by oral and transdermal routes fulfilling current recommendations regarding the use of a low dose and the nonoral route. Both intramuscular monthly administered formulations of E/P non-polymeric microspheres had favorable pharmacokinetic and safety profiles, suggesting this route as an interesting, novel, and suitable way of treating menopause-related symptoms.

Swiftia sahlingi sp. nov. Figures 1���4 Material examined. Holotype: MZUCR 2725, SIO-BIC Co2917, ethanol preserved, Mound 12, 1000 m, HOV Alvin Dive 4908, pilot Jefferson Grau, R /V Atlantis Expedition AT 37-13, 23 May 2017. Paratypes: MZUCR 1967, ethanol preserved, Mound 12, AT15-44, HOV Alvin, Dive 4501, pilot M. Spear, 1000 m, 22 February 2009. MZUCR 2726, 2 specimens, ethanol preserved, as the holotype; MZUCR 2647, 3 specimens, ethanol preserved, as the holotype; MZUCR 2648, SIO-BIC Co 2916, ethanol preserved, Mound 12, 999 m, HOV Alvin, Dive 4907, pilot J. Patrick Hickey, 22 May 2017. MZUCR 2727, 5 specimens; MZUCR 2650 (CR-AV-4909- 4), 2 specimens; MZUCR 2730 (CR-AV-4909-5), ethanol preserved; MZUCR 2727, ethanol preserved; MZUCR 2731, fragment, ethanol preserved, Mound 12, 996��� 1000 m, HOV Alvin, Dive 4909, pilot Mike Skowronski, 24 May 2017. MZUCR 2732, SIO-BIC Co 2935, dry, Mound 12, 1002 m, HOV Alvin, Dive 4917, pilot Jefferson Grau, 1 June 2017. MZUCR 2729, 2 specimens; MZUCR 2733, SIO-BIC Co 2945, 3 specimens, Mound 12, 996 m, HOV Alvin, Dive 4922, pilot Mike Skowronski, 5 June 2017. Type locality: Mound 12 (08��55.845��N, 084��18.768��W), 996���1002 m, Costa Rica Pacific margin. Description. The holotype is an erect, sparsely branched colony, 9 cm tall, and about 10 cm wide (Figs. 1A, 2A). It is attached to a 15-cm long rock together with a smaller colony (7 cm tall). The two colonies are about 2.5 cm apart, and arise from incrusting holdfasts about 1 cm in diameter each (Figs. 1A, 2 A���B). The main stem of the holotype is 3 mm in diameter at the base, and extends 7 mm tall, subdividing in 4 main branches that subdivide 2���3 times, branching up to five times (Fig. 1A). Branching is lateral and irregular in different planes. The branches are stout, and reach up to 2 mm in diameter including the polyp-mound. Unbranched terminal ends reach up to 8 cm in length. The flexible horny axis is light brown and somewhat translucent, with non-mineralised organic fibers. The main stem is devoid of polyps. The polyps are translucent (Figs. 1 B���C), and are about 1 mm apart. Polyp mounds are alternating, about 6 polyp mounds/cm at the end branchlets (n=8 branches) (Fig. 1A). The polyp mounds are perpendicular to the branches, raised up to 1 mm tall (Figs. 1 B���C) and about the same in width. The anthocodiae are preserved exsert, reaching up to 1 mm tall, and fully expanded, in life, up to 3 mm (Figs. 1 B���C, 2A���C). The coenenchyme is thin. Coenenchymal sclerites consist of long, thin, warty spindles, mostly straight, 0.26��� 0.60 mm long and 0.04���0.09 mm wide (Figs. 3A, 4A). Conspicuous plates with sparse tubercular sculpture, 0.153 ��� 0.315 mm long and 0.05���0.08 mm wide (Figs. 3A, 4C) are surrounding the polyp mound, at the neck zone of the anthocodiae and also occur in the external layer. The sclerites in the axial sheath are mostly tuberculated spindles, straight and curved; and immature sclerites (Figs. 3A, 4B). The anthocodial armature is arranged &Dot;en chevron&Dot; with points consisting of bar-like rods, straight or slightly bent, 0.28���0.44 mm long, and 0.04���0.08 mm wide (Fig. 4D), warty clubs with tuberculated or bifurcated heads, 0.19���0.39 mm long, and 0.034 ���0.075 mm wide (Fig. 4E), and irregular flattened rods around the peristome and along the tentacles, up to the tips, 0.10���0.19 mm long and 0.022 ���0.049 mm wide (Figs. 3B, 4E). Tentacular sclerites are colourless (Fig. 3B). The colour of the colony is red, and preserves the colour after fixation, sclerites are red, orange and of lighter hues (Figs. 1A, 3A). Variability. The paratypes are from 8 to 17 cm long (the largest MZUCR 2730). Specimens have up to 9 main branches that subsequently subdivide up to 8 times (MZUCR 1967). Unbranched terminal ends reach up to 8.5 cm (MZUCR 2729). Polyps are distributed as in the holotype, but more closely spaced, in some cases, i.e., 5���5.3 polyps/cm (n=20 branches); but they could be more distant at the base of the colonies, up to 2 mm apart (MZUCR 2729). Stems are normally devoid of polyps. In some cases, the lateral branches of neighbouring colonies could stick together forming a lose braid (e.g. MZUCR 1967, MZUCR 2650). The sclerite types, colours and sizes of the paratypes are similar to those of the holotype. Habitat. The species was found living in dense clusters on top of flat authigenic carbonate ledges (Figs. 2 A���D). Many of the observed and collected colonies were close to active methane seepage, and a colony was even observed on a tube of the polychaete Lamellibrachia (Siboglinidae). Nearby the collection location were clusters of mussels (Bathymodiolus spp.), bacterial mats and branching Foraminifera. Etymology. The species is named in memory of Heiko Sahling, a distinguished marine geologist who discovered and named Mound 12, the type locality of the new species., Published as part of Breedy, Odalisca, Rouse, Greg W., Stabbins, April, Cort��s, Jorge & Cordes, Erik E., 2019, New records of Swiftia (Cnidaria, Anthozoa, Octocorallia) from off the Pacific Costa Rican margin, including a new species from methane seeps, pp. 407-419 in Zootaxa 4671 (3) on pages 409-411, DOI: 10.11646/zootaxa.4671.3.6, http://zenodo.org/record/3442580