13,430 results on '"P. Hoff"'
Search Results
102. Sources of Nonlinear van't Hoff Temperature Dependence in High-Performance Liquid Chromatography.
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Tanase, Maria, Soare, Andreia, David, Victor, and Moldoveanu, Serban C.
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- 2019
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103. Identifying Causal Effects of Discrete, Ordered and ContinuousTreatments using Multiple Instrumental Variables
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Hoff, Nadja van 't
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Economics - Econometrics - Abstract
Inferring causal relationships from observational data is often challenging due to endogeneity. This paper provides new identification results for causal effects of discrete, ordered and continuous treatments using multiple binary instruments. The key contribution is the identification of a new causal parameter that has a straightforward interpretation with a positive weighting scheme and is applicable in many settings due to a mild monotonicity assumption. This paper further leverages recent advances in causal machine learning for both estimation and the detection of local violations of the underlying monotonicity assumption. The methodology is applied to estimate the returns to education and assess the impact of having an additional child on female labor market outcomes.
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- 2023
104. Nudging Nutrition: Lessons from the Danish 'Fat Tax'
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Dahl, Christian Møller, Hoff, Nadja van 't, Mellace, Giovanni, and Smed, Sinne
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Economics - General Economics - Abstract
In October 2011, Denmark introduced the world's first and, to date, only tax targeting saturated fat. However, this tax was subsequently abolished in January 2013. Leveraging exogenous variation from untaxed Northern-German consumers, we employ a difference-in-differences approach to estimate the causal effects of both the implementation and repeal of the tax on consumption and expenditure behavior across eight product categories targeted by the tax. Our findings reveal significant heterogeneity in the tax's impact across these products. During the taxed period, there was a notable decline in consumption of bacon, liver sausage, and cheese, particularly among low-income households. In contrast, expenditure on butter, cream, and margarine increased as prices rose. Interestingly, we do not observe any difference in expenditure increases between high and low-income households, suggesting that the latter were disproportionately affected by the tax. After the repeal of the tax, we do not observe any significant decline in consumption. On the contrary, there was an overall increase in consumption for certain products, prompting concerns about unintended consequences resulting from the brief implementation of the tax. Finally, we find strong evidence on an overall increase purchases of butter abroad for households living less than 50 km from the German boarder but we do not find strong evidence of spatial heterogeneous effects of the tax.
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- 2023
105. Total Skin Electron Therapy Stanford Technique Evolution With Monte Carlo Simulation Toward Personalized Treatments For Cutaneous Lymphoma
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Basaglia, Tullio, Boccacci, Patrizia, Chauvie, Stephane, Chessa, Manuela, DAgostino, Daniele, Gambaro, Monica, Ruggieri, Filippo Grillo, Hoff, Gabriela, Pia, Maria Grazia, Saracco, Paolo, Schiapparelli, Piero, Scielzo, Giuseppe, Tcherniaev, Evgueni, and Zefiro, Daniele
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Physics - Computational Physics ,Physics - Medical Physics - Abstract
Current Total Skin Electron Therapy (TSET) Stanford technique for cutaneous lymphoma, established in the 70's, involves a unique irradiation setup, i.e. patient's position and beam arrangement, for all patients with ensuing great variability in dose distribution and difficult dose optimization. A Geant4-based simulation has been developed to explore the possibility of personalizing the dose to each patient's anatomy. To achieve this optimization of the treatment method, this project enrolls different aspects of the clinical and computational techniques: starting with the knowledge of the experimental parameters involving TSET practice, passing through an innovative approach to model the patient's anatomy, a precise description of the electron beam and a validated configuration of the physics models handling the interactions of the electrons and of secondary particles. The Geant4-based simulation models the patient as a tessellated solid derived from the optical scan of her/his body, realistically reproduces the irradiation environment in detail and calculates the energy deposition corresponding to each facet of the patient's scanned surface. The resulting three-dimensional dose distribution constitutes the basis for the personalization of the medical treatement as appropriate to each patient's specific characteristics., Comment: Presented at the 2022 IEEE Nuclear Science Symposium
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- 2023
106. On parahoric $(\mathcal{G}, \mu)$-displays
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Hoff, Manuel
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Mathematics - Algebraic Geometry ,Mathematics - Number Theory - Abstract
We develop tools to study spaces of $p$-divisible groups and Abelian varieties with additional structure. More precisely, we extend the definition of parahoric (Dieudonn\'e) $(\mathcal{G}, \mu)$-displays given by Pappas to not necessarily $p$-torsionfree base rings and also introduce the notion of an $(m, n)$-truncated $(\mathcal{G}, \mu)$-display. Then we study the deformation theory of Dieudonn\'e $(\mathcal{G}, \mu)$-displays. As an application we realize the EKOR stratification of the special fiber of a Kisin-Pappas integral Shimura variety of Hodge type as the fibers of a smooth morphism into the algebraic stack of $(2, 1\text{-}\mathrm{rdt})$-truncated $(\mathcal{G}, \mu)$-displays., Comment: 37 pages
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- 2023
107. Early Planet Formation in Embedded Disks (eDisk) XII: Accretion streamers, protoplanetary disk, and outflow in the Class I source Oph IRS63
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Flores, Christian, Ohashi, Nagayoshi, Tobin, John J., Jørgensen, Jes K., Takakuwa, Shigehisa, Li, Zhi-Yun, Lin, Zhe-Yu Daniel, Hoff, Merel L. R. van 't, Plunkett, Adele L., Yamato, Yoshihide, Sai, Jinshi, Koch, Patrick M., Yen, Hsi-Wei, Aikawa, Yuri, Aso, Yusuke, de Gregorio-Monsalvo, Itziar, Kido, Miyu, Kwon, Woojin, Lee, Jeong-Eun, Lee, Chang Won, Looney, Leslie W., Santamaría-Miranda, Alejandro, Sharma, Rajeeb, Thieme, Travis J., Williams, Jonathan P., Han, Ilseung, Narayanan, Suchitra, and Lai, Shih-Ping
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present ALMA observations of the Class I source Oph IRS63 in the context of the Early Planet Formation in Embedded Disks (eDisk) large program. Our ALMA observations of Oph IRS63 show a myriad of protostellar features, such as a shell-like bipolar outflow (in $^{12}$CO), an extended rotating envelope structure (in $^{13}$CO), a streamer connecting the envelope to the disk (in C$^{18}$O), and several small-scale spiral structures seen towards the edge of the dust continuum (in SO). By analyzing the velocity pattern of $^{13}$CO and C$^{18}$O, we measure a protostellar mass of $\rm M_\star = 0.5 \pm 0.2 $~$\rm M_\odot$ and confirm the presence of a disk rotating at almost Keplerian velocity that extends up to $\sim260$ au. These calculations also show that the gaseous disk is about four times larger than the dust disk, which could indicate dust evolution and radial drift. Furthermore, we model the C$^{18}$O streamer and SO spiral structures as features originating from an infalling rotating structure that continuously feeds the young protostellar disk. We compute an envelope-to-disk mass infall rate of $\sim 10^{-6}$~$\rm M_\odot \, yr^{-1}$ and compare it to the disk-to-star mass accretion rate of $\sim 10^{-8}$~$\rm M_\odot \, yr^{-1}$, from which we infer that the protostellar disk is in a mass build-up phase. At the current mass infall rate, we speculate that soon the disk will become too massive to be gravitationally stable., Comment: 26 pages and 17 figures
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- 2023
108. Early Planet Formation in Embedded Disks (eDisk) X: Compact Disks, Extended Infall, and a Fossil Outburst in the Class I Oph IRS43 Binary
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Narayanan, Suchitra, Williams, Jonathan P., Tobin, John J., Jorgensen, Jes K., Ohashi, Nagayoshi, Lin, Zhe-Yu Daniel, Hoff, Merel L. R. van't, Li, Zhi-Yun, Plunkett, Adele L., Looney, Leslie W., Takakuwa, Shigehisa, Yen, Hsi-Wei, Aso, Yusuke, Flores, Christian, Lee, Jeong-Eun, Lai, Shih-Ping, Kwon, Woojin, de Gregorio-Monsalvo, Itziar, Sharma, Rajeeb, and Lee, Chang Won
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
We present the first results from the Early Planet Formation in Embedded Disks (eDisk) ALMA Large Program toward Oph IRS43, a binary system of solar mass protostars. The 1.3 mm dust continuum observations resolve a compact disk, ~6au radius, around the northern component and show that the disk around the southern component is even smaller, <~3 au. CO, 13CO, and C18O maps reveal a large cavity in a low mass envelope that shows kinematic signatures of rotation and infall extending out to ~ 2000au. An expanding CO bubble centered on the extrapolated location of the source ~130 years ago suggests a recent outburst. Despite the small size of the disks, the overall picture is of a remarkably large and dynamically active region., Comment: Paper 10 of the ALMA eDisk Large Program. Accepted for publication in ApJ
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- 2023
109. Linear Source Apportionment using Generalized Least Squares
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Bryan, Jordan and Hoff, Peter
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Statistics - Applications ,Statistics - Methodology - Abstract
Motivated by applications to water quality monitoring using fluorescence spectroscopy, we develop the source apportionment model for high dimensional profiles of dissolved organic matter (DOM). We describe simple methods to estimate the parameters of a linear source apportionment model, and show how the estimates are related to those of ordinary and generalized least squares. Using this least squares framework, we analyze the variability of the estimates, and we propose predictors for missing elements of a DOM profile. We demonstrate the practical utility of our results on fluorescence spectroscopy data collected from the Neuse River in North Carolina., Comment: 31 pages, 5 figures
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- 2023
110. Bonds and Bytes: the Odyssey of Structural Biology
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Hoff, Samuel, Zinke, Maximilian, Izadi-Pruneyre, Nadia, and Bonomi, Massimiliano
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Quantitative Biology - Quantitative Methods - Abstract
Characterizing structural and dynamic properties of proteins and large macromolecular assemblies is crucial to understand the molecular mechanisms underlying biological functions. In the field of Structural Biology, no single method comprehensively reveals the behavior of biological systems across various spatio-temporal scales. Instead, we have a versatile toolkit of techniques, each contributing a piece to the overall puzzle. Integrative Structural Biology combines different techniques to create accurate and precise multi-scale models that expand our understanding of complex biological systems. This review outlines recent advancements in computational and experimental methods in Structural Biology, with special focus on recent Artificial Intelligence techniques, emphasizes integrative approaches that combine different types of data for precise spatio-temporal modeling, and provides an outlook into future directions of this field., Comment: 16 pages, 2 figures
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- 2023
111. ICML 2023 Topological Deep Learning Challenge : Design and Results
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Papillon, Mathilde, Hajij, Mustafa, Jenne, Helen, Mathe, Johan, Myers, Audun, Papamarkou, Theodore, Birdal, Tolga, Dey, Tamal, Doster, Tim, Emerson, Tegan, Gopalakrishnan, Gurusankar, Govil, Devendra, Guzmán-Sáenz, Aldo, Kvinge, Henry, Livesay, Neal, Mukherjee, Soham, Samaga, Shreyas N., Ramamurthy, Karthikeyan Natesan, Karri, Maneel Reddy, Rosen, Paul, Sanborn, Sophia, Walters, Robin, Agerberg, Jens, Barikbin, Sadrodin, Battiloro, Claudio, Bazhenov, Gleb, Bernardez, Guillermo, Brent, Aiden, Escalera, Sergio, Fiorellino, Simone, Gavrilev, Dmitrii, Hassanin, Mohammed, Häusner, Paul, Gardaa, Odin Hoff, Khamis, Abdelwahed, Lecha, Manuel, Magai, German, Malygina, Tatiana, Ballester, Rubén, Nadimpalli, Kalyan, Nikitin, Alexander, Rabinowitz, Abraham, Salatiello, Alessandro, Scardapane, Simone, Scofano, Luca, Singh, Suraj, Sjölund, Jens, Snopov, Pavel, Spinelli, Indro, Telyatnikov, Lev, Testa, Lucia, Yang, Maosheng, Yue, Yixiao, Zaghen, Olga, Zia, Ali, and Miolane, Nina
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Computer Science - Machine Learning - Abstract
This paper presents the computational challenge on topological deep learning that was hosted within the ICML 2023 Workshop on Topology and Geometry in Machine Learning. The competition asked participants to provide open-source implementations of topological neural networks from the literature by contributing to the python packages TopoNetX (data processing) and TopoModelX (deep learning). The challenge attracted twenty-eight qualifying submissions in its two-month duration. This paper describes the design of the challenge and summarizes its main findings.
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- 2023
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112. Strong evidence for 9N and the limits of existence of atomic nuclei
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Charity, R. J., Wylie, J., Wang, S. M., Webb, T. B., Brown, K. W., Cerizza, G., Chajecki, Z., Elson, J. M., Estee, J., Hoff, D. E. M, Kuvin, S. A., Lynch, W. G., Manfredi, J., Michel, N., McNeel, D. G., Morfouace, P., Nazarewicz, W., Pruitt, C. D., Santamaria, C., Sweany, S., Smith, J., Sobotka, L. G., Tsang, M. B., and Wuosmaa, A. H.
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Nuclear Experiment - Abstract
The boundaries of the Chart of Nuclides contain exotic isotopes that possess extreme proton-toneutron asymmetries. Here we report on strong evidence of 9N, one of the most exotic proton-rich isotopes where more than one half of its constitute nucleons are unbound. With seven protons and two neutrons, this extremely proton-rich system would represent the first-known example of a ground-state five-proton emitter. The invariant-mass spectrum of its decay products can be fit with two peaks whose energies are consistent with the theoretical predictions of an open-quantum-system approach, however we cannot rule out the possibility that only a single resonance-like peak is present in the spectrum., Comment: 4 figures, 7pages
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- 2023
113. Local versus global subtleties of projective representations
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da Silva, J. M. Hoff and Rodrigues, J. E.
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Mathematical Physics - Abstract
In this short review, we pay attention to some subtleties in the study of projective representations, contrasting local to global properties and their interplay. The analysis is exposed rigorously, showing and demonstrating the main necessary theorems. We discuss the implementation of useful algebraic topology tools to characterize representations., Comment: 14 pages, to appear as a chapter in "Tribute to Ruben Aldrovandi", ed. by F. Caruso, J. G. Pereira, A. Santoro (Editora Livraria da F\'isica, S\~ao Paulo, 2024)
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- 2023
114. Poliovirus-Neutralizing Antibody Seroprevalence and Vaccine Habits in a Vaccine-Derived Poliovirus Outbreak Region in the Democratic Republic of Congo in 2018: The Impact on the Global Eradication Initiative.
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Musene, Kamy, Dzogang, Camille, Sinai, Cyrus, Spencer, DAndre, Ngoie-Mwamba, Guillaume, Tangney, Sylvia, Salet, Frank, Nyembwe, Michel, Kambamba Nzaji, Michel, Tambu, Merly, Mbala, Placide, Gerber, Sue, Kaba, Didine, Muyembe-Tamfum, Jean, Rimoin, Anne, Gadoth, Adva, Mukadi, Patrick, Fuller, Trevon, Hoff, Nicole, and Halbrook, Megan
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Democratic Republic of the Congo ,IPV ,OPV ,SIAs ,cVDPV ,nOPV2 ,poliovirus ,serosurvey ,vaccine coverage - Abstract
Despite the successes in wild-type polio eradication, poor vaccine coverage in the DRC has led to the occurrence of circulating vaccine-derived poliovirus outbreaks. This cross-sectional population-based survey provides an update to previous poliovirus-neutralizing antibody seroprevalence studies in the DRC and quantifies risk factors for under-immunization and parental knowledge that guide vaccine decision making. Among the 964 children between 6 and 35 months in our survey, 43.8% (95% CI: 40.6-47.0%), 41.1% (38.0-44.2%), and 38.0% (34.9-41.0%) had protective neutralizing titers to polio types 1, 2, and 3, respectively. We found that 60.7% of parents reported knowing about polio, yet 25.6% reported knowing how it spreads. Our data supported the conclusion that polio outreach efforts were successfully connecting with communities-79.4% of participants had someone come to their home with information about polio, and 88.5% had heard of a polio vaccination campaign. Additionally, the odds of seroreactivity to only serotype 2 were far greater in health zones that had a history of supplementary immunization activities (SIAs) compared to health zones that did not. While SIAs may be reaching under-vaccinated communities as a whole, these results are a continuation of the downward trend of seroprevalence rates in this region.
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- 2024
115. A reference genome for ecological restoration of the sunflower sea star, Pycnopodia helianthoides.
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Schiebelhut, Lauren, DeBiasse, Melissa, Gabriel, Lars, Hoff, Katharina, and Dawson, Michael
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Asteroidea ,climate change ,conservation ,kelp forest ,ocean health ,sea star wasting ,Animals ,Helianthus ,Starfish ,Genome ,Genomics ,Chromosomes - Abstract
Wildlife diseases, such as the sea star wasting (SSW) epizootic that outbroke in the mid-2010s, appear to be associated with acute and/or chronic abiotic environmental change; dissociating the effects of different drivers can be difficult. The sunflower sea star, Pycnopodia helianthoides, was the species most severely impacted during the SSW outbreak, which overlapped with periods of anomalous atmospheric and oceanographic conditions, and there is not yet a consensus on the cause(s). Genomic data may reveal underlying molecular signatures that implicate a subset of factors and, thus, clarify past events while also setting the scene for effective restoration efforts. To advance this goal, we used Pacific Biosciences HiFi long sequencing reads and Dovetail Omni-C proximity reads to generate a highly contiguous genome assembly that was then annotated using RNA-seq-informed gene prediction. The genome assembly is 484 Mb long, with contig N50 of 1.9 Mb, scaffold N50 of 21.8 Mb, BUSCO completeness score of 96.1%, and 22 major scaffolds consistent with prior evidence that sea star genomes comprise 22 autosomes. These statistics generally fall between those of other recently assembled chromosome-scale assemblies for two species in the distantly related asteroid genus Pisaster. These novel genomic resources for P. helianthoides will underwrite population genomic, comparative genomic, and phylogenomic analyses-as well as their integration across scales-of SSW and environmental stressors.
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- 2024
116. From strength to precision: A systematic review exploring the clinical utility of 7-Tesla magnetic resonance imaging in abdominal imaging.
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Perera Molligoda Arachchige, Arosh, Teixeira de Castro Gonçalves Ortega, Ana, Catapano, Federica, Politi, Letterio, and Hoff, Michael
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7-Tesla magnetic resonance imaging ,Abdominal ,Hepatobiliary ,Kidney ,Liver ,Pancreas ,Prostate ,Renal ,Small bowel - Abstract
BACKGROUND: After approval for clinical use in 2017 early investigations of ultra-high-field abdominal magnetic resonance imaging (MRI) have demonstrated the feasibility as well as diagnostic capabilities of liver, kidney, and prostate MRI at 7-Tesla. However, the elevation of the field strength to 7-Tesla not only brought advantages to abdominal MRI but also presented considerable challenges and drawbacks, primarily stemming from heightened artifacts and limitations in Specific Absorption Rate, etc. Furthermore, evidence in the literature is relatively scarce concerning human studies in comparison to phantom/animal studies which necessitates an investigation into the evidence so far in humans and summarizing all relevant evidence. AIM: To offer a comprehensive overview of current literature on clinical abdominal 7T MRI that emphasizes current trends, details relevant challenges, and provides a concise set of potential solutions. METHODS: This systematic review adheres to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A PubMed search, utilizing Medical Subject Headings terms such as 7-Tesla and organ-specific terms, was conducted for articles published between January 1, 1985, and July 25, 2023. Eligibility criteria included studies exploring 7T MRI for imaging human abdominal organs, encompassing various study types (in-vivo/ex-vivo, method development, reviews/meta-analyses). Exclusion criteria involved animal studies and those lacking extractable data. Study selection involved initial identification via title/abstract, followed by a full-text review by two researchers, with discrepancies resolved through discussion. Data extraction covered publication details, study design, population, sample size, 7T MRI protocol, image characteristics, endpoints, and conclusions. RESULTS: The systematic review included a total of 21 studies. The distribution of clinical 7T abdominal imaging studies revealed a predominant focus on the prostate (n = 8), followed by the kidney (n = 6) and the hepatobiliary system (n = 5). Studies on these organs, and in the pancreas, demonstrated clear advantages at 7T. However, small bowel studies showed no significant improvements compared to traditional MRI at 1.5T. The majority of studies evaluated originated from Germany (n = 10), followed by the Netherlands (n = 5), the United States (n = 5), Austria (n = 2), the United Kingdom (n = 1), and Italy (n = 1). CONCLUSION: Further increase of abdominal clinical MRI field strength to 7T demonstrated high imaging potential, yet also limitations mainly due to the inhomogeneous radiofrequency (RF) excitation field relative to lower field strengths. Hence, further optimization of dedicated RF coil elements and pulse sequences are expected to better optimize clinical imaging at high magnetic field strength.
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- 2024
117. The use of 7T MRI in multiple sclerosis: review and consensus statement from the North American Imaging in Multiple Sclerosis Cooperative.
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Harrison, Daniel, Sati, Pascal, Klawiter, Eric, Narayanan, Sridar, Bagnato, Francesca, Beck, Erin, Barker, Peter, Calvi, Alberto, Cagol, Alessandro, Donadieu, Maxime, Duyn, Jeff, Granziera, Cristina, Henry, Roland, Huang, Susie, Hoff, Michael, Mainero, Caterina, Ontaneda, Daniel, Reich, Daniel, Rudko, David, Smith, Seth, Trattnig, Siegfried, Zurawski, Jonathan, Bakshi, Rohit, Gauthier, Susan, and Laule, Cornelia
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7 Tesla ,magnetic resonance imaging ,multiple sclerosis ,ultra-high field - Abstract
The use of ultra-high-field 7-Tesla (7T) MRI in multiple sclerosis (MS) research has grown significantly over the past two decades. With recent regulatory approvals of 7T scanners for clinical use in 2017 and 2020, the use of this technology for routine care is poised to continue to increase in the coming years. In this context, the North American Imaging in MS Cooperative (NAIMS) convened a workshop in February 2023 to review the previous and current use of 7T technology for MS research and potential future research and clinical applications. In this workshop, experts were tasked with reviewing the current literature and proposing a series of consensus statements, which were reviewed and approved by the NAIMS. In this review and consensus paper, we provide background on the use of 7T MRI in MS research, highlighting this technologys promise for identification and quantification of aspects of MS pathology that are more difficult to visualize with lower-field MRI, such as grey matter lesions, paramagnetic rim lesions, leptomeningeal enhancement and the central vein sign. We also review the promise of 7T MRI to study metabolic and functional changes to the brain in MS. The NAIMS provides a series of consensus statements regarding what is currently known about the use of 7T MRI in MS, and additional statements intended to provide guidance as to what work is necessary going forward to accelerate 7T MRI research in MS and translate this technology for use in clinical practice and clinical trials. This includes guidance on technical development, proposals for a universal acquisition protocol and suggestions for research geared towards assessing the utility of 7T MRI to improve MS diagnostics, prognostics and therapeutic efficacy monitoring. The NAIMS expects that this article will provide a roadmap for future use of 7T MRI in MS.
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- 2024
118. Flares of autoimmune rheumatic disease following COVID‐19 infection: Observations from the COVAD study
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Sandhu, Nimrat Kaur, Ravichandraan, Naveen, Nune, Arvind, Day, Jessica, Sen, Parikshit, Nikiphorou, Elena, Tan, Ai Lyn, Joshi, Mrudula, Saha, Sreoshy, Shinjo, Samuel Katsuyuki, Jagtap, Kshitij, Agarwal, Vishwesh, Ziade, Nelly, Velikova, Tsvetelina, Milchert, Marcin, Parodis, Ioannis, Gracia‐Ramos, Abraham Edgar, Cavagna, Lorenzo, Kuwana, Masataka, Knitza, Johannes, Makol, Ashima, Patel, Aarat, Pauling, John D, Wincup, Chris, Barman, Bhupen, Tehozol, Erick Adrian Zamora, Serrano, Jorge Rojas, La Torre, Ignacio García‐De, Colunga‐Pedraza, Iris J, Merayo‐Chalico, Javier, Okwara, Celestine Chibuzo, Katchamart, Wanruchada, Goo, Phonpen Akawatcharangura, Shumnalieva, Russka, Chen, Yi‐Ming, Hoff, Leonardo Santos, Kibbi, Lina El, Halabi, Hussein, Vaidya, Binit, Shaharir, Syahrul Sazliyana, Hasan, ATM Tanveer, Dey, Dzifa, Gutiérrez, Carlos Enrique Toro, Caballero‐Uribe, Carlo Vinicio, Lilleker, James B, Salim, Babur, Gheita, Tamer, Saavedra, Miguel A, Chatterjee, Tulika, Distler, Oliver, Group, COVAD Study, Chinoy, Hector, Agarwal, Vikas, Aggarwal, Rohit, and Gupta, Latika
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Biomedical and Clinical Sciences ,Immunology ,Autoimmune Disease ,Emerging Infectious Diseases ,Infectious Diseases ,Arthritis ,Coronaviruses ,Humans ,COVID-19 ,Rheumatic Diseases ,Autoimmune Diseases ,COVAD Study Group ,Arthritis & Rheumatology - Published
- 2024
119. Nutritional Status Link with Polioseronegativity Among Children from Poliomyelitis Transmission High-Risk Area of the Democratic Republic of the Congo (DRC).
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Mwamba, Guillaume, Nzaji, Michel, Sinai, Cyrus, Fuller, Trevon, Numbi, Oscar, Wemakoy, Emile, Tamfum, Jean, Mukadi, Dalau, Mapatano, Mala, Rimoin, Anne, Dikassa, Paul-Samson, Mukadi, Patrick, Musene, Kamy, Gerber, Sue, Hoff, Nicole, and Halbrook, Megan
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DRC ,children ,malnutrition ,polioserotype ,seronegativity ,underweight - Abstract
BACKGROUND: Malnutrition is identified as a risk-factor for insufficient polioseroconversion in the context of a vaccine-derived polio virus (VDPV) outbreak prone region. To assess the prevalence of malnutrition and its link to poliovirus insufficient immunity, a cross-sectional household survey was conducted in the regions of Haut- Lomami and Tanganyika, DRC. METHODS: In March 2018, we included 968 healthy children aged 6 to 59 months from eight out of 27 districts. Selection of study locations within these districts was done using a stratified random sampling method, where villages were chosen based on habitat characteristics identified from satellite images. Consent was obtained verbally in the preferred language of the participant (French or Swahili) by interviewers who received specific training for this task. Furthermore, participants contributed a dried blood spot sample, collected via finger prick. To assess malnutrition, we measured height and weight, applying WHO criteria to determine rates of underweight, wasting, and stunting. The assessment of immunity to poliovirus types 1, 2, and 3 through the detection of neutralizing antibodies was carried out at the CDC in Atlanta, USA. RESULTS: Of the study population, we found 24.7% underweight, 54.8% stunted, and 15.4% wasted. With IC95%, underweight (OR=1.50; [1.11-2.03]), and the non-administration of vitamin A (OR=1.96; [1.52-2.54]) were significantly associated with seronegativity to polioserotype 1. Underweight (OR=1.64; [1.20-2.24]) and the non-administration of vitamin A (OR=1.55; [1.20-2.01]) were significantly associated with seronegativity to polioserotype 2. Underweight (OR=1.50; [1.11-2.03]), and the non-administration of vitamin A (OR=1.80. [1.38-2.35]) were significantly associated with seronegativity to polioserotype 3. Underweight (OR=1.68; IC95% [1.10-2.57]) and the non-administration of vitamin A (OR=1.82; IC95% [1.30-2.55]) were significantly associated with seronegativity to all polioserotypes. CONCLUSION: This study reveals a significant association between underweight and polioseronegativity in children. In order to reduce vaccine failures in high-risk areas, an integrated approach by vaccination and nutrition programs should be adopted.
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- 2024
120. Clade I-Associated Mpox Cases Associated with Sexual Contact, the Democratic Republic of the Congo.
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Bogoch, Isaac, Cevik, Muge, Gonsalves, Gregg, Hensley, Lisa, Low, Nicola, Shaw, Souradet, Schillberg, Erin, Hunter, Mikayla, Lunyanga, Lygie, Linsuke, Sylvie, Madinga, Joule, Peeters, Martine, Cigolo, Jean-Claude, Ahuka-Mundeke, Steve, Muyembe, Jean-Jacques, Rimoin, Anne, Kindrachuk, Jason, Mbala-Kingebeni, Placide, Lushima, Robert, Kibungu, Emile, Vakaniaki, Emmanuel, Kinganda-Lusamaki, Eddy, Kalonji-Mukendi, Thierry, Pukuta, Elisabeth, and Hoff, Nicole
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MPXV ,monkeypox virus ,mpox ,sexually transmitted infections ,the Democratic Republic of the Congo ,viruses ,Humans ,Mpox (monkeypox) ,Monkeypox virus ,Democratic Republic of the Congo ,Polymerase Chain Reaction - Abstract
We report a cluster of clade I monkeypox virus infections linked to sexual contact in the Democratic Republic of the Congo. Case investigations resulted in 5 reverse transcription PCR-confirmed infections; genome sequencing suggest they belonged to the same transmission chain. This finding demonstrates that mpox transmission through sexual contact extends beyond clade IIb.
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- 2024
121. Film and the Intercultural Multimodal Reader: Expanding Intercultural Literary Literacy as a Theoretical and Pedagogical Concept
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Hoff, Hild Elisabeth and Habegger-Conti, Jena
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This article addresses key theoretical and practical concerns related to the intercultural encounter with multimodal literature. Previous efforts to incorporate an intercultural dimension into conceptualisations of literary literacy have primarily focused on competences associated with the reading of traditional, script-based texts. However, as the term "literature" is today associated with a wide range of new media texts, there is a need to take this into account in theoretical constructs as well as in pedagogical practice. The article provides insight into how the multimodal elements of "film" function as a complex meaning-making ensemble which adds layers of potential insight as well as potential misunderstanding to the text interpretation process. With a basis in the Model of the Intercultural Reader (Hoff, 2016), the article sheds light on how issues related to the narrative style and structure of a Hollywood motion picture can be navigated through an exploration of the recognisable audio-visual rhetoric of oft-repeated tropes. Drawing on Baz Luhrmann's film "Romeo + Juliet" as a practical example, concrete suggestions for pedagogical practice are offered. By integrating practices of script-based intercultural reading with new literacies, the article expands upon previous theorisations of the intercultural reader and provides insight into how teachers may facilitate nuanced intercultural explorations of literary multimodal texts in the 21st century language classroom.
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- 2022
122. Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19 epidemics.
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Matteson, Nathaniel, Hassler, Gabriel, Kurzban, Ezra, Schwab, Madison, Perkins, Sarah, Gangavarapu, Karthik, Levy, Joshua, Parker, Edyth, Pride, David, Hakim, Abbas, De Hoff, Peter, Cheung, Willi, Castro-Martinez, Anelizze, Rivera, Andrea, Veder, Anthony, Rivera, Ariana, Wauer, Cassandra, Holmes, Jacqueline, Wilson, Jedediah, Ngo, Shayla, Plascencia, Ashley, Lawrence, Elijah, Smoot, Elizabeth, Eisner, Emily, Tsai, Rebecca, Chacón, Marisol, Baer, Nathan, Seaver, Phoebe, Salido, Rodolfo, Aigner, Stefan, Ngo, Toan, Barber, Tom, Ostrander, Tyler, Fielding-Miller, Rebecca, Simmons, Elizabeth, Zazueta, Oscar, Serafin-Higuera, Idanya, Sanchez-Alavez, Manuel, Moreno-Camacho, Jose, García-Gil, Abraham, Murphy Schafer, Ashleigh, McDonald, Eric, Corrigan, Jeremy, Malone, John, Stous, Sarah, Shah, Seema, Moshiri, Niema, Weiss, Alana, Anderson, Catelyn, Aceves, Christine, Spencer, Emily, Hufbauer, Emory, Lee, Justin, King, Alison, Ramesh, Karthik, Nguyen, Kelly, Saucedo, Kieran, Robles-Sikisaka, Refugio, Fisch, Kathleen, Gonias, Steven, Birmingham, Amanda, McDonald, Daniel, Karthikeyan, Smruthi, Martin, Natasha, Schooley, Robert, Negrete, Agustin, Reyna, Horacio, Chavez, Jose, Garcia, Maria, Cornejo-Bravo, Jose, Becker, David, Isaksson, Magnus, Washington, Nicole, Lee, William, Garfein, Richard, Luna-Ruiz Esparza, Marco, Alcántar-Fernández, Jonathan, Henson, Benjamin, Jepsen, Kristen, Olivares-Flores, Beatriz, Barrera-Badillo, Gisela, Lopez-Martínez, Irma, Ramírez-González, José, Flores-León, Rita, Kingsmore, Stephen, Sanders, Alison, Pradenas, Allorah, White, Benjamin, Matthews, Gary, Hale, Matt, McLawhon, Ronald, Reed, Sharon, Winbush, Terri, McHardy, Ian, Fielding, Russel, Nicholson, Laura, Quigley, Michael, Harding, Aaron, Mendoza, Art, and Bakhtar, Omid
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COVID-19 ,SARS-CoV-2 ,genomic epidemiology ,mobility ,phylogenetics ,travel restrictions ,viral sequencing ,Humans ,COVID-19 ,Genomics ,Pandemics ,Public Health ,SARS-CoV-2 ,Infection Control ,Geography - Abstract
The maturation of genomic surveillance in the past decade has enabled tracking of the emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, for example, genomic data revealed that local epidemics varied considerably in the frequency of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage importation and persistence, likely due to a combination of COVID-19 restrictions and changing connectivity. Here, we show that local COVID-19 epidemics are driven by regional transmission, including across international boundaries, but can become increasingly connected to distant locations following the relaxation of public health interventions. By integrating genomic, mobility, and epidemiological data, we find abundant transmission occurring between both adjacent and distant locations, supported by dynamic mobility patterns. We find that changing connectivity significantly influences local COVID-19 incidence. Our findings demonstrate a complex meaning of local when investigating connected epidemics and emphasize the importance of collaborative interventions for pandemic prevention and mitigation.
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- 2023
123. Strengthening immunization programs through innovative sub-national public-private partnerships in selected provinces in the Democratic Republic of the Congo.
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Banza Mpiongo, Patrick, Kibanza, Jerry, Kambol Yav, Francis, Nyombo, Didier, Mwepu, Lucie, Basame, Djogo, Mpoyi, Raoul, Madika, Collard, Hatton, Trad, Mafuta, Eric, Gascon, Oriane, Tschirhart, Kevin, Nkosi, Freddy, Lusamba, Paul, Merritt, Sydney, Mwenda, Julio, Tangney, Sylvia, Hoff, Nicole, Nkamba Mukadi, Dalau, Rimoin, Anne, Kaba, Didine, El Mourid, Amine, Senouci, Kamel, Ngoie Mwamba, Guillaume, Mukamba Musenga, Elisabeth, and Cikomola, Aimé
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DRC ,Memorandums of understanding ,Provincial autonomy ,Routine immunization ,Vaccine ,Child ,Humans ,Democratic Republic of the Congo ,Public-Private Sector Partnerships ,Immunization ,Vaccination ,Vaccines ,Poliomyelitis ,Immunization Programs - Abstract
BACKGROUND: Low immunization coverage rates in the Democratic Republic of Congo (DRC) have been reflective of challenges with vaccine access, support and delivery in the country. Motivated by measles and vaccine-derived polio virus (VDPV) outbreaks in 2016-17 and low vaccination rates, the provinces of Haut Lomami and Tanganyika were identified as pilot locations for an innovative approach focused on establishing a consortium of partners supporting local government. This approach was formalized through Memorandums of Understanding (MoUs) between the Bill and Melinda Gates Foundation and Provincial governments in 2018. A third province, Lualaba, established an MoU in 2021. MOU IMPLEMENTATION: These MoUs were 5-year partnerships designed to aid provinces in meeting four key objectives: 80 % immunization coverage, management/elimination of polio/cVDPV outbreaks, improvement of vaccine accessibility, and transfer of immunization service management to provincial leadership. OUTCOMES: During the MoU period, Haut-Lomami saw an increase in full immunization coverage, from 35.7 % (MICS 2018) to 88.9 % (VCS 2021-22), the highest in country. A sharp drop in percentage of zero-dose children was observed in the 3 provinces, confirming improved access to immunization services. Tanganyika saw initial improvement in full immunization coverage, followed by a drop in the VCS 2021-22 due to COVID-19 and healthcare worker strikes. Coverage improved in Tanganyika in the 2023 VCS. The 3 provinces increased their financial contributions to routine immunization and are now the top contributing provinces. While no cVDPV cases were recorded in 2020 and 2021, cVDPV1 and cVDPV2 outbreaks are afflicting the 3 provinces since 2022. CONCLUSIONS: Ultimately, the provincial MoUs were successful in bolstering provincial autonomy and capacity building with the biggest success being a drop in zero-dose children. While not all objectives have been met, the MoU approach served as an innovative program for key aspects of strengthening routine immunization in the DRC.
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- 2023
124. Inhibiting stromal Class I HDACs curbs pancreatic cancer progression.
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Liang, Gaoyang, Oh, Tae, Hah, Nasun, Tiriac, Hervé, Shi, Yu, Truitt, Morgan, Antal, Corina, Atkins, Annette, Li, Yuwenbin, Fraser, Cory, Ng, Serina, Pinto, Antonio, Nelson, Dylan, Estepa, Gabriela, Bashi, Senada, Banayo, Ester, Dai, Yang, Liddle, Christopher, Yu, Ruth, Hunter, Tony, Engle, Dannielle, Han, Haiyong, Von Hoff, Daniel, Downes, Michael, and Evans, Ronald
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Animals ,Mice ,Cell Line ,Tumor ,Pancreatic Neoplasms ,Pancreas ,Carcinoma ,Pancreatic Ductal ,Fibroblasts ,Carcinogenesis ,Tumor Microenvironment - Abstract
Oncogenic lesions in pancreatic ductal adenocarcinoma (PDAC) hijack the epigenetic machinery in stromal components to establish a desmoplastic and therapeutic resistant tumor microenvironment (TME). Here we identify Class I histone deacetylases (HDACs) as key epigenetic factors facilitating the induction of pro-desmoplastic and pro-tumorigenic transcriptional programs in pancreatic stromal fibroblasts. Mechanistically, HDAC-mediated changes in chromatin architecture enable the activation of pro-desmoplastic programs directed by serum response factor (SRF) and forkhead box M1 (FOXM1). HDACs also coordinate fibroblast pro-inflammatory programs inducing leukemia inhibitory factor (LIF) expression, supporting paracrine pro-tumorigenic crosstalk. HDAC depletion in cancer-associated fibroblasts (CAFs) and treatment with the HDAC inhibitor entinostat (Ent) in PDAC mouse models reduce stromal activation and curb tumor progression. Notably, HDAC inhibition (HDACi) enriches a lipogenic fibroblast subpopulation, a potential precursor for myofibroblasts in the PDAC stroma. Overall, our study reveals the stromal targeting potential of HDACi, highlighting the utility of this epigenetic modulating approach in PDAC therapeutics.
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- 2023
125. The impact of obesity surgery on newborn anthropometrics in women with and without polycystic ovary syndrome
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Huke, Camilla Johannesen, Romsaas, Therese, Vanky, Eszter, Huse, Karoline, Ødegård, Rønnaug, Nymo, Siren, Hoff, Dag Arne Lihaug, and Sandvik, Jorunn
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- 2024
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126. Randomised controlled pilot trial to assess effect of electrical stimulation of weak pelvic floor muscles
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Brækken, Ingeborg Hoff, Villumstad, Tove K. L. S., and Evensen, Natalie Michelle
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- 2024
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127. Information Geometry and Asymptotics for Kronecker Covariances
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McCormack, Andrew and Hoff, Peter
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Mathematics - Statistics Theory ,62 - Abstract
We explore the information geometry and asymptotic behaviour of estimators for Kronecker-structured covariances, in both growing-$n$ and growing-$p$ scenarios, with a focus towards examining the quadratic form or partial trace estimator proposed by Linton and Tang. It is shown that the partial trace estimator is asymptotically inefficient An explanation for this inefficiency is that the partial trace estimator does not scale sub-blocks of the sample covariance matrix optimally. To correct for this, an asymptotically efficient, rescaled partial trace estimator is proposed. Motivated by this rescaling, we introduce an orthogonal parameterization for the set of Kronecker covariances. High-dimensional consistency results using the partial trace estimator are obtained that demonstrate a blessing of dimensionality. In settings where an array has at least order three, it is shown that as the array dimensions jointly increase, it is possible to consistently estimate the Kronecker covariance matrix, even when the sample size is one., Comment: 42 total pages, 21 pages of main text, 4 tables, 8 figures
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- 2023
128. Quantum key distribution for data center security -- a feasibility study
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Jain, Nitin, Hoff, Ulrich, Gambetta, Marco, Rodenberg, Jesper, and Gehring, Tobias
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Quantum Physics ,Computer Science - Cryptography and Security - Abstract
Data centers are nowadays referred to as the digital world's cornerstone. Quantum key distribution (QKD) is a method that solves the problem of distributing cryptographic keys between two entities, with the security rooted in the laws of quantum physics. This document provides an assessment of the need and opportunity for ushering QKD in data centers. Together with technical examples and inputs on how QKD has and could be integrated into data-center like environments, the document also discusses the creation of value through future-proof data security as well as the market potential that QKD brings on the table through e.g., crypto-agility. While primarily addressed to data center owners/operators, the document also offers a knowledge base to QKD vendors planning to diversify to the data center market segment., Comment: 23 pages, 7 figures, study initiated and supported by Copenhagen Fintech (see https://www.copenhagenfintech.dk/projects/using-qkd-for-data-center-security)
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- 2023
129. Beyond Hiding and Revealing: Exploring Effects of Visibility and Form of Interaction on the Witness Experience
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Uhde, Alarith, Hoff, Tim zum, and Hassenzahl, Marc
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Computer Science - Human-Computer Interaction - Abstract
Our interactions with technology do not just shape our individual experiences. They also affect people around us. Although previous research has addressed such "witness" experiences, the actual effect of interaction design on the witness experience remains largely unknown. In an online study (n = 407), we explored how witnesses perceive mid-air gesture-based interactions with a hearing aid, using four video vignettes. We studied witnesses' subjective visibility of manipulations and effects (following Reeves and colleagues' taxonomy), perceived form of interaction, subjective experience, and relationships between these measures. Although visibility patterns matched the intended form, they did not lead to the supposed experience (i.e., "suspenseful" gestures did not lead to suspenseful experiences). The paper illustrates gaps in current research about witness experiences, demonstrates the need to overcome basic hiding/revealing profiles, and indicates a path forward by focusing on aesthetic forms and experiences., Comment: 23 pages, 4 figures
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- 2023
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130. Early Planet Formation in Embedded Disks (eDisk). VII. Keplerian Disk, Disk Substructure, and Accretion Streamers in the Class 0 Protostar IRAS 16544-1604 in CB 68
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Kido, Miyu, Takakuwa, Shigehisa, Saigo, Kazuya, Ohashi, Nagayoshi, Tobin, John J., K, Jes, Jørgensen, Aikawa, Yuri, Aso, Yusuke, Encalada, Frankie J., Flores, Christian, Gavino, Sacha, de Gregorio-Monsalvo, Itziar, Han, Ilseung, Hirano, Shingo, Koch, Patrick M., Kwon, Woojin, Lai, Shih-Ping, Lee, Chang Won, Lee, Jeong-Eun, Li, Zhi-Yun, Lin, Zhe-Yu Daniel, Looney, Leslie W., Mori, Shoji, Narayanan, Suchitra, Plunkett, Adele L., Phuong, Nguyen Thi, Sai, Jinshi, Santamarîa-Miranda, Alejandro, Sharma, Rajeeb, Sheehan, Patrick, Thieme, Travis J., Tomida, Kengo, Hoff, Merel L. R. van't, Williams, Jonathan P., Yamato, Yoshihide, and Yen, Hsi-Wei
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present observations of the Class 0 protostar IRAS 16544-1604 in CB 68 from the ''Early Planet Formation in Embedded Disks (eDisk)'' ALMA Large program. The ALMA observations target continuum and lines at 1.3-mm with an angular resolution of $\sim$5 au. The continuum image reveals a dusty protostellar disk with a radius of $\sim$30 au seen close to edge-on, and asymmetric structures both along the major and minor axes. While the asymmetry along the minor axis can be interpreted as the effect of the dust flaring, the asymmetry along the major axis comes from a real non-axisymmetric structure. The C$^{18}$O image cubes clearly show the gas in the disk that follows a Keplerian rotation pattern around a $\sim$0.14 $M_{\odot}$ central protostar. Furthermore, there are $\sim$1500 au-scale streamer-like features of gas connecting from North-East, North-North-West, and North-West to the disk, as well as the bending outflow as seen in the $^{12}$CO (2-1) emission. At the apparent landing point of NE streamer, there are SO (6$_5$-5$_4$) and SiO (5-4) emission detected. The spatial and velocity structure of NE streamer can be interpreted as a free-falling gas with a conserved specific angular momentum, and the detection of the SO and SiO emission at the tip of the streamer implies presence of accretion shocks. Our eDisk observations have unveiled that the Class 0 protostar in CB 68 has a Keplerian rotating disk with flaring and non-axisymmetric structure associated with accretion streamers and outflows., Comment: 30 pages, 24 figures, accepted for publication in The Astrophysical Journal as one of the first-look papers of the eDisk ALMA Large Program
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- 2023
131. Early Planet Formation in Embedded Disks (eDisk). II. Limited Dust Settling and Prominent Snow Surfaces in the Edge-on Class I Disk IRAS 04302+2247
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Lin, Zhe-Yu Daniel, Li, Zhi-Yun, Tobin, John J., Ohashi, Nagayoshi, Jørgensen, Jes Kristian, Looney, Leslie W., Aso, Yusuke, Takakuwa, Shigehisa, Aikawa, Yuri, Hoff, Merel L. R. van 't, de Gregorio-Monsalvo, Itziar, Encalada, Frankie J., Flores, Christian, Gavino, Sacha, Han, Ilseung, Kido, Miyu, Koch, Patrick M., Kwon, Woojin, Lai, Shih-Ping, Lee, Chang Won, Lee, Jeong-Eun, Phuong, Nguyen Thi, Sai, Jinshi, Sharma, Rajeeb, Sheehan, Patrick, Thieme, Travis J., Williams, Jonathan P., Yamato, Yoshihide, and Yen, Hsi-Wei
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
While dust disks around optically visible, Class II protostars are found to be vertically thin, when and how dust settles to the midplane are unclear. As part of the Atacama Large Millimeter/submillimeter Array (ALMA) large program, Early Planet Formation in Embedded Disks, we analyze the edge-on, embedded, Class I protostar IRAS 04302+2247, also nicknamed the ``Butterfly Star." With a resolution of 0.05" (8~au), the 1.3 mm continuum shows an asymmetry along the minor axis which is evidence of an optically thick and geometrically thick disk viewed nearly edge-on. There is no evidence of rings and gaps, which could be due to the lack of radial substructure or the highly inclined and optically thick view. With 0.1" (16~au) resolution, we resolve the 2D snow surfaces, i.e., the boundary region between freeze-out and sublimation, for $^{12}$CO $J$=2--1, $^{13}$CO $J$=2--1, C$^{18}$O $J$=2--1, $H_{2}$CO $J$=$3_{0,3}$--$2_{0,2}$, and SO $J$=$6_{5}$--$5_{4}$, and constrain the CO midplane snow line to $\sim 130$ au. We find Keplerian rotation around a protostar of $1.6 \pm 0.4 M_{\odot}$ using C$^{18}$O. Through forward ray-tracing using RADMC-3D, we find that the dust scale height is $\sim 6$ au at a radius of 100~au from the central star and is comparable to the gas pressure scale height. The results suggest that the dust of this Class~I source has yet to vertically settle significantly., Comment: 33 pages, 21 figures. Accepted for publication in ApJ as one of the first-look papers of the eDisk ALMA Large Program
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- 2023
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132. Early Planet Formation in Embedded Disks (eDisk). IV. The Ringed and Warped Structure of the Disk around the Class I Protostar L1489 IRS
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Yamato, Yoshihide, Aikawa, Yuri, Ohashi, Nagayoshi, Tobin, John J., Jørgensen, Jes K., Takakuwa, Shigehisa, Aso, Yusuke, Sai, Jinshi, Flores, Christian, de Gregorio-Monsalvo, Itziar, Hirano, Shingo, Han, Ilseung, Kido, Miyu, Koch, Patrick M., Kwon, Woojin, Lai, Shih-Ping, Lee, Chang Won, Lee, Jeong-Eun, Li, Zhi-Yun, Lin, Zhe-Yu Daniel, Looney, Leslie W., Mori, Shoji, Narayanan, Suchitra, Phuong, Nguyen Thi, Saigo, Kazuya, Santamaría-Miranda, Alejandro, Sharma, Rajeeb, Thieme, Travis J., Tomida, Kengo, Hoff, Merel L. R. van 't, and Yen, Hsi-Wei
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Constraining the physical and chemical structure of young embedded disks is crucial to understanding the earliest stages of planet formation. As part of the Early Planet Formation in Embedded Disks Atacama Large Millimeter/submillimeter Array Large Program, we present high spatial resolution ($\sim$0$.\!\!^{\prime\prime}$1 or $\sim$15 au) observations of the 1.3 mm continuum and $^{13}$CO $J=$ 2-1, C$^{18}$O $J=$ 2-1, and SO $J_N=$ $6_5$-$5_4$ molecular lines toward the disk around the Class I protostar L1489 IRS. The continuum emission shows a ring-like structure at 56 au from the central protostar and a tenuous, optically thin emission extending beyond $\sim$300 au. The $^{13}$CO emission traces the warm disk surface, while the C$^{18}$O emission originates from near the disk midplane. The coincidence of the radial emission peak of C$^{18}$O with the dust ring may indicate a gap-ring structure in the gaseous disk as well. The SO emission shows a highly complex distribution, including a compact, prominent component at $\lesssim$30 au, which is likely to originate from thermally sublimated SO molecules. The compact SO emission also shows a velocity gradient along a slightly ($\sim15^\circ$) tilted direction with respect to the major axis of the dust disk, which we interpret as an inner warped disk in addition to the warp around $\sim$200 au suggested by previous work. These warped structures may be formed by a planet or companion with an inclined orbit, or by a gradual change in the angular momentum axis during gas infall., Comment: 24 pages, 12 figures. Accepted for publication in The Astrophysical Journal as one of the first-look papers of the eDisk ALMA Large Program
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- 2023
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133. Early Planet Formation in Embedded Disks (eDisk) III: A first high-resolution view of sub-mm continuum and molecular line emission toward the Class 0 protostar L1527 IRS
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Hoff, Merel L. R. van 't, Tobin, John J., Li, Zhi-Yun, Ohashi, Nagayoshi, Jørgensen, Jes K., Lin, Zhe-Yu Daniel, Aikawa, Yuri, Aso, Yusuke, de Gregorio-Monsalvo, Itziar, Gavino, Sacha, Han, Ilseung, Koch, Patrick M., Kwon, Woojin, Lee, Chang Won, Lee, Jeong-Eun, Looney, Leslie W., Narayanan, Suchitra, Plunkett, Adele, Sai, Jinshi, Santamaría-Miranda, Alejandro, Sharma, Rajeeb, Sheehan, Patrick D., Takakuwa, Shigehisa, Thieme, Travis J., Williams, Jonathan P., Lai, Shih-Ping, Phuong, Nguyen Thi, and Yen, Hsi-Wei
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Studying the physical and chemical conditions of young embedded disks is crucial to constrain the initial conditions for planet formation. Here, we present Atacama Large Millimeter/submillimeter Array (ALMA) observations of dust continuum at $\sim$0.06" (8 au) resolution and molecular line emission at $\sim$0.17" (24 au) resolution toward the Class 0 protostar L1527 IRS from the Large Program eDisk (Early Planet Formation in Embedded Disks). The continuum emission is smooth without substructures, but asymmetric along both the major and minor axes of the disk as previously observed. The detected lines of $^{12}$CO, $^{13}$CO, C$^{18}$O, H$_2$CO, c-C$_3$H$_2$, SO, SiO, and DCN trace different components of the protostellar system, with a disk wind potentially visible in $^{12}$CO. The $^{13}$CO brightness temperature and the H$_2$CO line ratio confirm that the disk is too warm for CO freeze out, with the snowline located at $\sim$350 au in the envelope. Both molecules show potential evidence of a temperature increase around the disk-envelope interface. SO seems to originate predominantly in UV-irradiated regions such as the disk surface and the outflow cavity walls rather than at the disk-envelope interface as previously suggested. Finally, the continuum asymmetry along the minor axis is consistent with the inclination derived from the large-scale (100" or 14,000 au) outflow, but opposite to that based on the molecular jet and envelope emission, suggesting a misalignment in the system. Overall, these results highlight the importance of observing multiple molecular species in multiple transitions to characterize the physical and chemical environment of young disks., Comment: 27 pages, 16 figures, 2 tables, 10 pages appendix with 12 figures. Accepted for publication in ApJ as one of the first-look papers of the eDisk ALMA Large Program
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- 2023
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134. Early Planet Formation in Embedded Disks (eDisk). I. Overview of the Program and First Results
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Ohashi, Nagayoshi, Tobin, John J., Jørgensen, Jes K., Takakuwa, Shigehisa, Sheehan, Patrick, Aikawa, Yuri, Li, Zhi-Yun, Looney, Leslie W., Willians, Jonathan P., Aso, Yusuke, Sharma, Rajeeb, Sai, Jinshi, Yamato, Yoshihide, Lee, Jeong-Eun, Tomida, Kengo, Yen, Hsi-Wei, Encalada, Frankie J, Flores, Christian, Gavino, Sacha, Kido, Miyu, Han, Ilseung, Lin, Zhe-Yu Daniel, Narayanan, Suchitra, Phuong, Nguyen Thi, Santamaría-Miranda, Alejandro, Thieme, Travis J., Hoff, Merel L. R. van 't, de Gregorio-Monsalvo, Itziar, Koch, Patrick M., Kwon, Woojin, Lai, Shih-Ping, Lee, Chang Won, Plunkett, Adele, Saigo, Kazuya, Hirano, Shingo, Lam, Ka Ho, and Mori, Shoji
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present an overview of the Large Program, ``Early Planet Formation in Embedded Disks (eDisk)'', conducted with the Atacama Large Millimeter/submillimeter Array (ALMA). The ubiquitous detections of substructures, particularly rings and gaps, in protoplanetary disks around T Tauri stars raise the possibility that at least some planet formation may have already started during the embedded stages of star formation. In order to address exactly how and when planet formation is initiated, the program focuses on searching for substructures in disks around 12 Class 0 and 7 Class I protostars in nearby ($< $200 pc) star-forming regions through 1.3 mm continuum observations at a resolution of $\sim7$ au (0.04"). The initial results show that the continuum emission, mostly arising from dust disks around the sample protostars, has relatively few distinctive substructures, such as rings and spirals, in marked contrast to Class II disks. The dramatic difference may suggest that substructures quickly develop in disks when the systems evolve from protostars to Class II sources or alternatively that high optical depth of the continuum emission could obscure internal structures. Kinematic information obtained through CO isotopologue lines and other lines reveals the presence of Keplerian disks around protostars, providing us with crucial physical parameters, in particular, the dynamical mass of the central protostars. We describe the background of the eDisk program, the sample selection and their ALMA observations, the data reduction, and also highlight representative first-look results., Comment: This is a publication of a series of eDisk ALMA large program first-look papers
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- 2023
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135. Evidence for ubiquitous carbon grain destruction in hot protostellar envelopes
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Nazari, P., Tabone, B., Hoff, M. L. R. van 't, Jørgensen, J. K., and van Dishoeck, E. F.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Earth is deficient in carbon and nitrogen by up to ${\sim}4$ orders of magnitude compared with the Sun. Destruction of (carbon- and nitrogen-rich) refractory organics in the high-temperature planet forming regions could explain this deficiency. Assuming a refractory cometary composition for these grains, their destruction enhances nitrogen-containing oxygen-poor molecules in the hot gas ($\gtrsim 300$K) after the initial formation and sublimation of these molecules from oxygen-rich ices in the warm gas (${\sim}150$K). Using observations of $37$ high-mass protostars with ALMA, we find that oxygen-containing molecules (CH$_3$OH and HNCO) systematically show no enhancement in their hot component. In contrast, nitrogen-containing, oxygen-poor molecules (CH$_3$CN and C$_2$H$_3$CN) systematically show an enhancement of a factor ${\sim} 5$ in their hot component, pointing to additional production of these molecules in the hot gas. Assuming only thermal excitation conditions, we interpret these results as a signature of destruction of refractory organics, consistent with the cometary composition. This destruction implies a higher C/O and N/O in the hot gas than the warm gas, while, the exact values of these ratios depend on the fraction of grains that are effectively destroyed. This fraction can be found by future chemical models that constrain C/O and N/O from the abundances of minor carbon, nitrogen and oxygen carriers presented here., Comment: Accepted for publication in ApJ Letters
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- 2023
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136. GHOST Commissioning Science Results: Identifying a new chemically peculiar star in Reticulum II
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Hayes, Christian R., Venn, Kim A., Waller, Fletcher, Jensen, Jaclyn, McConnachie, Alan W., Pazder, John, Sestito, Federico, Anthony, Andre, Baker, Gabriella, Bassett, John, Bento, Joao, Burley, Gregory, Brzeski, Jurek, Case, Scott, Chapin, Edward, Chin, Timothy, Chisholm, Eric, Churilov, Vladimir, Densmore, Adam, Diaz, Ruben, Dunn, Jennifer, Edgar, Michael, Farrell, Tony, Firpo, Veronica, Fitzsimmons, Joeleff, Font-Serra, Juan, Fuentes, Javier, Ganton, Colin, Gomez-Jimenez, Manuel, Hardy, Tim, Henderson, David, Hill, Alexis, Hoff, Brian, Ireland, Michael, Kalari, Venu, Kelly, Neal, Klauser, Urs, Kondrat, Yuriy, Labrie, Kathleen, Lambert, Sam, Luvaul, Lance, Lawrence, Jon, Lothrop, Jordan, Macdonald, G. Scott, Mali, Slavko, Margheim, Steve, McDermid, Richard, McGregor, Helen, Miller, Bryan, Miranda, Felipe, Muller, Rolf, Nielsen, Jon, Norbury, Ryan, Oberdorf, Oliver, Pai, Naveen, Perez, Gabriel, Prado, Pablo, Price, Ian, Quiroz, Carlos, Reshetov, Vladimir, Robertson, Gordon, Ruiz-Carmona, Roque, Salinas, Ricardo, Sebo, Kim M., Sheinis, Andrew, Shetrone, Matthew, Shortridge, Keith, Silversides, Katherine, Silva, Karleyne, Simpson, Chris, Smith, Greg, Szeto, Kei, Tims, Julia, Toro, Eduardo, Urrutia, Cristian, Venkatesan, Sudharshan, Waller, Lewis, Wevers, Ivan, Wierzbicki, Ramunas, White, Marc, Young, Peter, and Zhelem, Ross
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Astrophysics - Astrophysics of Galaxies - Abstract
The Gemini High-resolution Optical SpecTrograph (GHOST) is the newest high resolution spectrograph to be developed for a large aperture telescope, recently deployed and commissioned at the Gemini-South telescope. In this paper, we present the first science results from the GHOST spectrograph taking during its commissioning runs. We have observed the bright metal-poor benchmark star HD 122563, along with two stars in the ultra faint dwarf galaxy, Ret II, one of which was previously identified as a candidate member, but did not have a previous detailed chemical abundance analysis. This star (GDR3 0928) is found to be a bona fide member of Ret II, and from a spectral synthesis analysis, it is also revealed to be a CEMP-r star, with significant enhancements in the several light elements (C, N, O, Na, Mg, and Si), in addition to featuring an r-process enhancement like many other Ret II stars. The light-element enhancements in this star resemble the abundance patterns seen in the CEMP-no stars of other ultra faint dwarf galaxies, and are thought to have been produced by an independent source from the r-process. These unusual abundance patterns are thought to be produced by faint supernovae, which may be produced by some of the earliest generations of stars., Comment: 23 pages, 9 figures, 7 tables, submitted to the AAS Journals
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- 2023
137. Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer
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Rajbhandari, Nirakar, Hamilton, Michael, Quintero, Cynthia M, Ferguson, L Paige, Fox, Raymond, Schürch, Christian M, Wang, Jun, Nakamura, Mari, Lytle, Nikki K, McDermott, Matthew, Diaz, Emily, Pettit, Hannah, Kritzik, Marcie, Han, Haiyong, Cridebring, Derek, Wen, Kwun Wah, Tsai, Susan, Goggins, Michael G, Lowy, Andrew M, Wechsler-Reya, Robert J, Von Hoff, Daniel D, Newman, Aaron M, and Reya, Tannishtha
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Immunology ,Biotechnology ,Rare Diseases ,Digestive Diseases ,Genetics ,Human Genome ,Pancreatic Cancer ,Cancer ,1.1 Normal biological development and functioning ,2.1 Biological and endogenous factors ,Mice ,Animals ,Carcinoma ,Pancreatic Ductal ,Pancreatic Neoplasms ,Musashi ,Myc ,acinar cell carcinoma ,adenosquamous carcinoma ,cancer ,cell of origin stem cells ,pancreatic cancer ,single cell ,tumor evolution ,Neurosciences ,Oncology & Carcinogenesis ,Biochemistry and cell biology ,Oncology and carcinogenesis - Abstract
Identifying the cells from which cancers arise is critical for understanding the molecular underpinnings of tumor evolution. To determine whether stem/progenitor cells can serve as cells of origin, we created a Msi2-CreERT2 knock-in mouse. When crossed to CAG-LSL-MycT58A mice, Msi2-CreERT2 mice developed multiple pancreatic cancer subtypes: ductal, acinar, adenosquamous, and rare anaplastic tumors. Combining single-cell genomics with computational analysis of developmental states and lineage trajectories, we demonstrate that MYC preferentially triggers transformation of the most immature MSI2+ pancreas cells into multi-lineage pre-cancer cells. These pre-cancer cells subsequently diverge to establish pancreatic cancer subtypes by activating distinct transcriptional programs and large-scale genomic changes, and enforced expression of specific signals like Ras can redirect subtype specification. This study shows that multiple pancreatic cancer subtypes can arise from a common pool of MSI2+ cells and provides a powerful model to understand and control the programs that shape divergent fates in pancreatic cancer.
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- 2023
138. The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries.
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Nachega, Jean, Mbala-Kingebeni, Placide, Rosenthal, Philip, Rimoin, Anne, Hoff, Nicole, Liesenborghs, Laurens, Vanlerberghe, Veerle, Andrei, Graciela, Rawat, Angeli, Wilson, Lindsay, Forrest, Jamie, Mills, Edward, Hermans, Michel, Mulangu, Sabue, Ntoumi, Francine, Zumla, Alimuddin, and Muyembe-Tamfum, Jean-Jacques
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Humans ,Disease Outbreaks ,Mpox (monkeypox) ,Animals ,Global Health ,Monkeypox virus ,Endemic Diseases ,Zoonoses - Abstract
The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the viruss natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging zoonotic pathogens to address them locally and prevent or quickly control their worldwide spread. Political endorsement from individual countries and financial commitments to maintain control efforts will be essential for long-term sustainability.
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- 2023
139. Experimental Study of the $^{\textbf{38}}$S Excited Level Scheme
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Hoffman, C. R., Lubna, R. S., Rubino, E., Tabor, S. L., Auranen, K., Bender, P. C., Campbell, C. M., Carpenter, M. P., Chen, J., Gott, M., Greene, J. P., Hoff, D. E. M., Huang, T., Iwasaki, H., Kondev, F. G., Lauritsen, T., Longfellow, B., Santamaria, C., Seweryniak, D., Tang, T. L., Wilson, G. L., Wu, J., and Zhu, S.
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Nuclear Experiment - Abstract
Information on the $^{38}$S level scheme was expanded through experimental work utilizing a fusion-evaporation reaction and in-beam $\gamma$-ray spectroscopy. Prompt $\gamma$-ray transitions were detected by the Gamma-Ray Energy Tracking Array (GRETINA) and recoiling $^{38}$S residues were selected by the Fragment Mass Analayzer (FMA). Tools based on machine-learning techniques were developed and deployed for the first time in order to enhance the unique selection of $^{38}$S residues and identify any associated $\gamma$-ray transitions. The new level information, including the extension of the even-spin yrast sequence through $J^{\pi} = 8^{(+)}$, was interpreted in terms of a basic single-particle picture as well shell-model calculations which incorporated the empirically derived FSU interaction. A comparison between the properties of the yrast states in the even-$Z$ $N=22$ isotones from $Z=14$ to $20$, and for $^{36}$Si-$^{38}$S in particular, was also presented with an emphasis on the role and influence of the neutron $1p_{3/2}$ orbital on the structure in the region.
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- 2023
- Full Text
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140. Perturbative aspects of mass dimension one fermions non-minimally coupled to electromagnetic field
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Carvalho, Willian, Dias, M., Lehum, A. C., and da Silva, J. M. Hoff
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High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
This paper addresses perturbative aspects of the renormalization of a fermion with mass dimension one non-minimally coupled to the electromagnetic field. Specifically, we calculate the one-loop corrections to the propagators and vertex functions of the model and determine the one-loop beta function of the non-minimal electromagnetic coupling. Additionally, we perform calculations of the two-loop corrections to the gauge field propagator, demonstrating that it remains massless and transverse up to this order. We also find that the non-minimal electromagnetic coupling can exhibit asymptotic freedom if a certain condition is satisfied. As a potential dark matter candidate, these findings suggest that the field may decouple at high energies. This aspect holds significance for calculating the relic abundance and freeze-out temperature of the field, particularly in relation to processes involving the ordinary particles of the Standard Model., Comment: 13 pages, 5 figures
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- 2023
141. Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies
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Mason, James Paul, Werth, Alexandra, West, Colin G., Youngblood, Allison A., Woodraska, Donald L., Peck, Courtney, Lacjak, Kevin, Frick, Florian G., Gabir, Moutamen, Alsinan, Reema A., Jacobsen, Thomas, Alrubaie, Mohammad, Chizmar, Kayla M., Lau, Benjamin P., Dominguez, Lizbeth Montoya, Price, David, Butler, Dylan R., Biron, Connor J., Feoktistov, Nikita, Dewey, Kai, Loomis, N. E., Bodzianowski, Michal, Kuybus, Connor, Dietrick, Henry, Wolfe, Aubrey M., Guerrero, Matt, Vinson, Jessica, Starbuck, Peter, Litton, Shelby D, Beck, M. G., Fisch, Jean-Paul, West, Ayana, Muniz, Alexis A., Chavez, Luis, Upthegrove, Zachary T., Runyon, Brenton M., Salazar, J., Kritzberg, Jake E., Murrel, Tyler, Ho, Ella, LaFemina, Quintin Y., Elbashir, Sara I., Chang, Ethan C., Hudson, Zachary A., Nussbaum, Rosemary O., Kennedy, Kellen, Kim, Kevin, Arango, Camila Villamil, Albakr, Mohammed A., Rotter, Michael, Garscadden, A. J., Salcido-Alcontar JR, Antonio, Pearl, Harrison M., Stepaniak, Tyler, Marquez, Josie A., Marsh, Lauren, Andringa, Jesse C, Osogwin, Austin, Shields, Amanda M., Brookins, Sarah, Hach, Grace K., Clausi, Alexis R., Millican, Emily B., Jaimes, Alan A, Graham, Alaina S., Burritt, John J., Perez, J. S., Ramirez, Nathaniel, Suri, Rohan, Myer, Michael S., Kresek, Zoe M., Goldsberry, C. A., Payne, Genevieve K., Jourabchi, Tara, Hu, J., Lucca, Jeffrey, Feng, Zitian, Gilpatrick, Connor B., Khan, Ibraheem A., Warble, Keenan, Sweeney, Joshua D., Dorricott, Philip, Meyer, Ethan, Kothamdi, Yash S., Sohail, Arman S., Grell, Kristyn, Floyd, Aidan, Bard, Titus, Mathieson, Randi M., Reed, Joseph, Cisneros, Alexis, Payne, Matthew P., Jarriel, J. R., Mora, Jacqueline Rodriguez, Sundell, M. E., Patel, Kajal, Alesmail, Mohammad, Alnasrallah, Yousef A, Abdullah, Jumana T., Molina-Saenz, Luis, Tayman, K. E., Brown, Gabriel T., Kerr-Layton, Liana, Berriman-Rozen, Zachary D., Hiatt, Quinn, Kalra, Etash, Ong, Jason, Vadayar, Shreenija, Shannahan, Callie D., Benke, Evan, zhang, Jinhua, Geisman, Jane, Martyr, Cara, Ameijenda, Federico, Akruwala, Ushmi H., Nehring, Molly, Kissner, Natalie, Rule, Ian C., Learned, Tyler, Smith, Alexandra N., Mazzotta, Liam, Rounsefell, Tyndall, Eyeson, Elizabeth A., Shelby, Arlee K., Moll, Tyler S, Menke, Riley, Shahba, Hannan, House Jr., Tony A., Clark, David B., Burns, Annemarie C., de La Beaujardiere, Tristan, Trautwein, Emily D., Plantz, Will, Reeves, Justin, Faber, Ian, Buxton, B. W., Highhouse, Nigel, Landrey, Kalin, Hansen, Connor M, Chen, Kevin, Hales, Ryder Buchanan, Borgerding, Luke R., Guo, Mutian, Crow, Christian J., Whittall, Lloyd C., Simmons, Conor, Folarin, Adeduni, Parkinson, Evan J., Rahn, Anna L., Blevins, Olivia, Morelock, Annalise M., Kelly, Nicholas, Parker, Nathan L., Smith, Kelly, Plzak, Audrey E., Saeb, David, Hares, Cameron T., Parker, Sasha R., McCoy, Andrew, Pham, Alexander V., Lauzon, Megan, Kennedy, Cayla J., Reyna, Andrea B., Acosta, Daniela M. Meza, Cool, Destiny J., Steinbarth, Sheen L., Mendoza-Anselmi, Patricia, Plutt, Kaitlyn E., Kipp, Isabel M, Rakhmonova, M., Brown, Cameron L., Van Anne, Gabreece, Moss, Alexander P., Golden, Olivia, Kirkpatrick, Hunter B., Colleran, Jake R., Sullivan, Brandon J, Tran, Kevin, Carpender, Michael Andrew, Mundy, Aria T., Koenig, Greta, Oudakker, Jessica, Engelhardt, Rasce, Ales, Nolan, Wexler, Ethan Benjamin, Beato, Quinn I, Chen, Lily, Cochran, Brooke, Hill, Paula, Hamilton, Sean R., Hashiro, Kyle, Khan, Usman, Martinez, Alexa M., Brockman, Jennifer L., Mallory, Macguire, Reed, Charlie, Terrile, Richard, Singh, Savi, Watson, James Adam, Creany, Joshua B., Price, Nicholas K., Miften, Aya M., Tran, Bryn, Kamenetskiy, Margaret, Martinez, Jose R., Opp, Elena N., Huang, Jianyang, Fails, Avery M., Belei, Brennan J., Slocum, Ryan, Astalos, Justin, East, Andrew, Nguyen, Lena P., Pherigo, Callie C, East, Andrew N., Li, David Y., Nelson, Maya LI, Taylor, Nicole, Odbayar, Anand, Rives, Anna Linnea, Mathur, Kabir P., Billingsley, Jacob, Polikoff, Hyden, Driscoll, Michael, Wilson, Orion K., Lahmers, Kyle, Toon, Nathaniel J., Lippincott, Sam, Musgrave, Andrew J., Gregory, Alannah H., Pitsuean-Meier, Sedique, Jesse, Trevor, Smith, Corey, Miles, Ethan J., Kainz, Sabrina J. H. T., Ji, Soo Yeun, Nguyen, Lena, Aryan, Maryam, Dinser, Alexis M., Shortman, Jadon, Bastias, Catalina S, Umbricht, Thomas D, Cage, Breonna, Randolph, Parker, Pollard, Matthew, Simone, Dylan M., Aramians, Andrew, Brecl, Ariana E., Robert, Amanda M., Zenner, Thomas, Saldi, Maxwell, Morales, Gavin, Mendez, Citlali, Syed, Konner, Vogel, Connor Maklain, Cone, Rebecca A., Berhanu, Naomi, Carpenter, Emily, Leoni, Cecilia, Bryan, Samuel, Ramachandra, Nidhi, Shaw, Timothy, Lee, E. C., Monyek, Eli, Wegner, Aidan B., Sharma, Shajesh, Lister, Barrett, White, Jamison R., Willard, John S., Sulaiman, S. A, Blandon, Guillermo, Narayan, Anoothi, Ruger, Ryan, Kelley, Morgan A., Moreno, Angel J., Balcer, Leo M, Ward-Chene, N. R. D., Shelby, Emma, Reagan, Brian D., Marsh, Toni, Sarkar, Sucheta, Kelley, Michael P., Fell, Kevin, Balaji, Sahana, Hildebrand, Annalise K., Shoha, Dominick, Nandu, Kshmya, Tucker, Julia, Cancio, Alejandro R., Wang, Jiawei, Rapaport, Sarah Grace, Maravi, Aimee S., Mayer, Victoria A., Miller, Andrew, Bence, Caden, Koke, Emily, Fauntleroy, John T, Doermer, Timothy, Al-Ghazwi, Adel, Morgan, Remy, Alahmed, Mohammed S., Mathavan, Adam Izz Khan Mohd Reduan, Silvester, H. K., Weiner, Amanda M., Liu, Nianzi, Iovan, Taro, Jensen, Alexander V., AlHarbi, Yazeed A., Jiang, Yufan, Zhang, Jiaqi, Jones, Olivia M., Huang, Chenqi, Reh, Eileen N., Alhamli, Dania, Pettine, Joshua, Zhou, Chongrui, Kriegman, Dylan, Yang, Jianing, Ash, Kevin, Savage, Carl, Kaiser, Emily, Augenstein, Dakota N., Padilla, Jacqueline, Stark, Ethan K., Hansen, Joshua A., Kokes, Thomas, Huynh, Leslie, Sanchez-Sanchez, Gustavo, Jeseritz, Luke A., Carillion, Emma L., Vepa, Aditya V., Khanal, Sapriya, Behr, Braden, Martin, Logan S., McMullan, Jesse J., Zhao, Tianwei, Williams, Abigail K., Alqabani, Emeen, Prinster, Gale H., Horne, Linda, Ruggles-Delgado, Kendall, Otto, Grant, Gomez, Angel R., Nguyen, Leonardo, Brumley, Preston J., Venegas, Nancy Ortiz, Varela, Ilian, Brownlow, Jordi, Cruz, Avril, Leiker, Linzhi, Batra, Jasleen, Hutabarat, Abigail P., Nunes-Valdes, Dario, Jameson, Connor, Naqi, Abdulaziz, Adams, Dante Q., Biediger, Blaine B., Borelli, William T, Cisne, Nicholas A., Collins, Nathaniel A., Curnow, Tyler L., Gopalakrishnan, Sean, Griffin, Nicholas F., Herrera, Emanuel, McGarvey, Meaghan V., Mellett, Sarah, Overchuk, Igor, Shaver, Nathan, Stratmeyer, Cooper N., Vess, Marcus T., Juels, Parker, Alyami, Saleh A., Gale, Skylar, Wallace, Steven P., Hunter, Samuel C, Lonergan, Mia C., Stewart, Trey, Maksimuk, Tiffany E., Lam, Antonia, Tressler, Judah, Napoletano, Elena R., Miller, Joshua B., Roy, Marc G., Chanders, Jasey, Fischer, Emmalee, Croteau, A. J., Kuiper, Nicolas A., Hoffman, Alex, DeBarros, Elyse, Curry, Riley T., Brzostowicz, A., Courtney, Jonas, Zhao, Tiannie, Szabo, Emi, Ghaith, Bandar Abu, Slyne, Colin, Beck, Lily, Quinonez, Oliver, Collins, Sarah, Madonna, Claire A., Morency, Cora, Palizzi, Mallory, Herwig, Tim, Beauprez, Jacob N., Ghiassi, Dorsa, Doran, Caroline R., Yang, Zhanchao, Padgette, Hannah M., Dicken, Cyrus A., Austin, Bryce W., Phalen, Ethan J., Xiao, Catherine, Palos, Adler, Gerhardstein, Phillip, Altenbern, Ava L., Orbidan, Dan, Dorr, Jackson A., Rivas, Guillermo A., Ewing, Calvin A, Giebner, B. C., McEntee, Kelleen, Kite, Emily R., Crocker, K. A., Haley, Mark S., Lezak, Adrienne R., McQuaid, Ella, Jeong, Jacob, Albaum, Jonathan, Hrudka, E. M., Mulcahy, Owen T., Tanguma, Nolan C., Oishi-Holder, Sean, White, Zachary, Coe, Ryan W., Boyer, Christine, Chapman, Mitchell G., Fortino, Elise, Salgado, Jose A., Hellweg, Tim, Martinez, Hazelia K., Mitchell, Alexander J., Schubert, Stephanie H., Schumacher, Grace K, Tesdahl, Corey D, Uphoff, C. H., Vassilyev, Alexandr, Witkoff, Briahn, Wolle, Jackson R., Dice, Kenzie A., Behrer, Timothy A., Bowen, Troy, Campbell, Andrew J, Clarkson, Peter C, Duong, Tien Q., Hawat, Elijah, Lopez, Christian, Olson, Nathaniel P., Osborn, Matthew, Peou, Munisettha E., Vaver, Nicholas J., Husted, Troy, Kallemeyn, Nicolas Ian, Spangler, Ava A, Mccurry, Kyle, Schultze, Courtney, Troisi, Thomas, Thomas, Daniel, Ort, Althea E., Singh, Maya A., Soon, Caitlin, Patton, Catherine, Billman, Jayce A., Jarvis, Sam, Hitt, Travis, Masri, Mirna, Albalushi, Yusef J., Schofer, Matthew J, Linnane, Katherine B., Knott, Philip Whiting, Valencia, Whitney, Arias-Robles, Brian A., Ryder, Diana, Simone, Anna, Abrams, Jonathan M., Belknap, Annelene L., Rouse, Charlotte, Reynolds, Alexander, Petric, Romeo S. L., Gomez, Angel A., Meiselman-Ashen, Jonah B., Carey, Luke, Dias, John S., Fischer-White, Jules, Forbes, Aidan E., Galarraga, Gabriela, Kennedy, Forrest, Lawlor, Rian, Murphy, Maxwell J., Norris, Cooper, Quarderer, Josh, Waller, Caroline, Weber, Robert J., Gunderson, Nicole, Boyne, Tom, Gregory, Joshua A., Propper, Henry Austin, von Peccoz, Charles B. Beck, Branch, Donovan, Clarke, Evelyn, Cutler, Libby, Dabberdt, Frederick M., Das, Swagatam, Figueirinhas, John Alfred D., Fougere, Benjamin L., Roy, Zoe A., Zhao, Noah Y., Cox, Corben L., Barnhart, Logan D. W., Craig, Wilmsen B., Moll, Hayden, Pohle, Kyle, Mueller, Alexander, Smith, Elena K., Spicer, Benjamin C., Aycock, Matthew C., Bat-Ulzii, Batchimeg, Murphy, Madalyn C., Altokhais, Abdullah, Thornally, Noah R., Kleinhaus, Olivia R., Sarfaraz, Darian, Barnes, Grant M., Beard, Sara, Banda, David J, Davis, Emma A. B., Huebsch, Tyler J., Wagoner, Michaela, Griego, Justus, Hale, Jack J. Mc, Porter, Trevor J., Abrashoff, Riley, Phan, Denise M., Smith, Samantha M., Srivastava, Ashish, Schlenker, Jared A. W., Madsen, Kasey O., Hirschmann, Anna E., Rankin, Frederick C, Akbar, Zainab A., Blouin, Ethan, Coleman-Plante, Aislinn, Hintsa, Evan, Lookhoff, Emily, Amer, Hamzi, Deng, Tianyue, Dvorak, Peter, Minimo, Josh, Plummer, William C., Ton, Kelly, Solt, Lincoln, AlAbbas, Batool H., AlAwadhi, Areej A., Cooper, Nicholas M., Corbitt, Jessica S, Dunlap, Christian, Johnson, Owen, Malone, Ryan A., Tellez, Yesica, Wallace, Logan, Ta, Michael-Tan D., Wheeler, Nicola H., Ramirez, Ariana C., Huang, Shancheng, Mehidic, Amar, Christiansen, Katherine E, Desai, Om, Domke, Emerson N., Howell, Noah H., Allsbrook, Martin, Alnaji, Teeb, England, Colin, Siles, Nathan, Burton, Nicholas David, Cruse, Zoe, Gilmartin, Dalton, Kim, Brian T., Hattendorf, Elsie, Buhamad, Maryam, Gayou, Lily, Seglem, Kasper, Alkhezzi, Tameem, Hicks, Imari R., Fife, Ryann, Pelster, Lily M., Fix, Alexander, Sur, Sohan N., Truong, Joshua K., Kubiak, Bartlomiej, Bondar, Matthew, Shi, Kyle Z., Johnston, Julia, Acevedo, Andres B., Lee, Junwon, Solorio, William J., Johnston, Braedon Y., McCormick, Tyler, Olguin, Nicholas, Pastor, Paige J., Wilson, Evan M., Trunko, Benjamin L., Sjoroos, Chris, Adams, Kalvyn N, Bell, Aislyn, Brumage-Heller, Grant, Canales, Braden P., Chiles, Bradyn, Driscoll, Kailer H., Hill, Hallie, Isert, Samuel A., Ketterer, Marilyn, Kim, Matthew M., Mewhirter, William J., Phillips, Lance, Phommatha, Krista, Quinn, Megan S., Reddy, Brooklyn J., Rippel, Matthew, Russell, Bowman, Williams, Sajan, Pixley, Andrew M., Gapin, Keala C., Peterson, B., Ruprecht, Collin, Hardie, Isabelle, Li, Isaac, Erickson, Abbey, Gersabeck, Clint, Gopalani, Mariam, Allanqawi, Nasser, Burton, Taylor, Cahn, Jackson R., Conti, Reese, White, Oliver S., Rojec, Stewart, Hogen, Blake A., Swartz, Jason R., Dick, R., Battist, Lexi, Dunn, Gabrielle M., Gasser, Rachel, Logan, Timothy W., Sinkovic, Madeline, Schaller, Marcus T., Heintz, Danielle A., Enrich, Andrew, Sanchez, Ethan S., Perez, Freddy, Flores, Fernando, Kapla, Shaun D., Shockley, Michael C., Phillips, Justin, Rumley, Madigan, Daboub, Johnston, Karsh, Brennan J., Linders, Bridget, Chen, Sam, Do, Helen C., Avula, Abhinav, French, James M., Bertuccio, Chrisanna, Hand, Tyler, Lee, Adrianna J., Neeland, Brenna K, Salazar, Violeta, Andrew, Carter, Barmore, Abby, Beatty, Thomas, Alonzi, Nicholas, Brown, Ryan, Chandler, Olivia M., Collier, Curran, Current, Hayden, Delasantos, Megan E., Bonilla, Alberto Espinosa de los Monteros, Fowler, Alexandra A., Geneser, Julianne R., Gentry, Eleanor, Gustavsson, E. R., Hansson, Jonathan, Hao, Tony Yunfei, Herrington, Robert N., Kelly, James, Kelly, Teagan, Kennedy, Abigail, Marquez, Mathew J., Meillon, Stella, Palmgren, Madeleine L., Pesce, Anneliese, Ranjan, Anurag, Robertson, Samuel M., Smith, Percy, Smith, Trevor J, Soby, Daniel A., Stratton, Grant L., Thielmann, Quinn N., Toups, Malena C., Veta, Jenna S., Young, Trenton J., Maly, Blake, Manzanares, Xander R., Beijer, Joshua, George, Jacob D., Mills, Dylan P., Ziebold, Josh J, Chambers, Paige, Montoya, Michael, Cheang, Nathan M., Anderson, Hunter J., Duncan, Sheridan J., Ehrlich, Lauren, Hudson, Nathan C., Kiechlin, Jack L., Koch, Will, Lee, Justin, Menassa, Dominic, Oakes, S. H., Petersen, Audrey J., Bunsow, J. R. Ramirez, Bay, Joshua, Ramirez, Sacha, Fenwick, Logan D., Boyle, Aidan P., Hibbard, Lea Pearl, Haubrich, Calder, Sherry, Daniel P., Jenkins, Josh, Furney, Sebastian, Velamala, Anjali A., Krueger, Davis J., Thompson, William N., Chhetri, Jenisha, Lee, Alexis Ying-Shan, Ray, Mia G. V., Recchia, John C., Lengerich, Dylan, Taulman, Kyle, Romero, Andres C., Steward, Ellie N., Russell, Sloan, Hardwick, Dillon F., Wootten, Katelynn, Nguyen, Valerie A., Quispe, Devon, Ragsdale, Cameron, Young, Isabel, Atchley-Rivers, N. S., Stribling, Jordin L., Gentile, Julia G, Boeyink, Taylor A., Kwiatkowski, Daniel, Dupeyron, Tomi Oshima, Crews, Anastasia, Shuttleworth, Mitchell, Dresdner, Danielle C., Flackett, Lydia, Haratsaris, Nicholas, Linger, Morgan I, Misener, Jay H., Patti, Samuel, Pine, Tawanchai P., Marikar, Nasreen, Matessi, Giorgio, Routledge, Allie C., Alkaabi, Suhail, Bartman, Jessica L., Bisacca, Gabrielle E., Busch, Celeste, Edwards, Bree, Staudenmier, Caitlyn, Starling, Travis, McVey, Caden, Montano, Maximus, Contizano, Charles J., Taylor, Eleanor, McIntyre, James K., Victory, Andrew, McCammon, Glen S., Kimlicko, Aspen, Sheldrake, Tucker, Shelchuk, Grace, Von Reich, Ferin J., Hicks, Andrew J., O'neill, Ian, Rossman, Beth, Taylor, Liam C., MacDonald, William, Becker, Simone E., Han, Soonhee, O'Sullivan, Cian, Wilcove, Isaac, Brennan, David J., Hanley, Luke C., Hull, Owen, Wilson, Timothy R., Kalmus, Madison H., Berv, Owen A., Harris, Logan Swous, Doan, Chris H, Londres, Nathan, Parulekar, Anish, Adam, Megan M., Angwin, Abigail, Cabbage, Carter C., Colleran, Zachary, Pietras, Alex, Seux, Octave, Oros, Ryan, Wilkinson, Blake C., Nguyen, Khoa D, Trank-Greene, Maedee, Barone, Kevin M., Snyder, G. L., Biehle, Samuel J, Billig, Brennen, Almquist, Justin Thomas, Dixon, Alyssa M., Erickson, Benjamin, Evans, Nathan, Genne, SL, Kelly, Christopher M, Marcus, Serafima M., Ogle, Caleb, Patel, Akhil, Vendetti, Evan, Courtney, Olivia, Deel, Sean, Del Foco, Leonardo, Gjini, Michael, Haines, Jessica, Hoff, Isabelle J., Jones, M. R., Killian, Dominic, Kuehl, Kirsten, Kuester, Chrisanne, Lantz, Maxwell B., Lee, Christian J, Mauer, Graham, McKemey, Finbar K., Millican, Sarah J., Rosasco, Ryan, Stewart, T. C., VanEtten, Eleanor, Derwin, Zachary, Serio, Lauren, Sickler, Molly G., Blake, Cassidy A., Patel, Neil S., Fox, Margaret, Gray, Michael J, Ziegler, Lucas J., Kumar, Aman Priyadarshi, Polly, Madelyn, Mesgina, Sarah, McMorris, Zane, Griffin, Kyle J., Haile, L. N., Bassel, Claire, Dixon, Thomas J., Beattie, Ryan, Houck, Timothy J, Rodgers, Maeve, Trofino, Tyson R., Lukianow, Dax, Smart, Korben, Hall, Jacqueline L., Bone, Lauren, Baldwin, James O., Doane, Connor, Almohsen, Yousef A., Stamos, Emily, Acha, Iker, Kim, Jake, Samour II, Antonio E., Chavali, S., Kanokthippayakun, Jeerakit, Gotlib, Nicholas, Murphy, Ryan C., Archibald, Jack. W., Brimhall, Alexander J, Boyer, Aidan, Chapman, Logan T., Chadda, Shivank, Sibrell, Lisa, Vallery, Mia M., Conroy, Thomas C., Pan, Luke J., Balajonda, Brian, Fuhrman, Bethany E. S., Alkubaisi, Mohamed, Engelstad, Jacob, Dodrill, Joshua, Fuchs, Calvin R., Bullard-Connor, Gigi, Alhuseini, Isehaq, Zygmunt, James C., Sipowicz, Leo, Hayrynen, Griffin A., McGill, Riley M., Keating, Caden J., Hart, Omer, Cyr, Aidan St., Steinsberger, Christopher H., Thoman, Gerig, Wood, Travis M., Ingram, Julia A., Dominguez, J., Georgiades, Nathaniel James, Johnson, Matthew, Johnson, Sawyer, Pedersen, Alexander J., Ralapanawe, Anoush K, Thomas, Jeffrey J., Sato, Ginn A., Reynolds, Hope, Nasser, Liebe, Mizzi, Alexander Z., Damgaard, Olivia, Baflah, Abdulrahman A., Liu, Steven Y., Salindeho, Adam D., Norden, Kelso, Gearhart, Emily E., Krajnak, Zack, Szeremeta, Philip, Amos, Meggan, Shin, Kyungeun, Muckenthaler, Brandon A., Medialdea, Melissa, Beach, Simone, Wilson, Connor B., Adams, Elena R, Aldhamen, Ahmed, Harris, Coyle M., Hesse, Troy M., Golding, Nathan T., Larter, Zachary, Hernandez, Angel, Morales, Genaro, Traxler, Robert B., Alosaimi, Meshal, Fitton, Aidan F., Aaron, James Holland, Lee, Nathaniel F., Liao, Ryan Z., Chen, Judy, French, Katherine V., Loring, Justin, Colter, Aurora, McConvey, Rowan, Colozzi, Michael, Vann, John D., Scheck, Benjamin T., Weigand, Anthony A, Alhabeeb, Abdulelah, Idoine, Yolande, Woodard, Aiden L., Medellin, Mateo M., Ratajczyk, Nicholas O, Tobin, Darien P., Collins, Jack C., Horning, Thomas M., Pellatz, Nick, Pitten, John, Lordi, Noah, Patterson, Alyx, Hoang, Thi D, Zimmermann, Ingrid H, Wang, Hongda, Steckhahn, Daniel, Aradhya, Arvind J., Oliver, Kristin A., Cai, Yijian, Wang, Chaoran, Yegovtsev, Nikolay, Wu, Mengyu, Ganesan, Koushik, Osborne, Andrew, Wickenden, Evan, Meyer, Josephine C., Chaparro, David, Visal, Aseem, Liu, Haixin, Menon, Thanmay S., Jin, Yan, Wilson, John, Erikson, James W., Luo, Zheng, Shitara, Nanako, Nelson, Emma E, Geerdts, T. R., Ortiz, Jorge L Ramirez, and Lewandowski, H. J.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
Flare frequency distributions represent a key approach to addressing one of the largest problems in solar and stellar physics: determining the mechanism that counter-intuitively heats coronae to temperatures that are orders of magnitude hotter than the corresponding photospheres. It is widely accepted that the magnetic field is responsible for the heating, but there are two competing mechanisms that could explain it: nanoflares or Alfv\'en waves. To date, neither can be directly observed. Nanoflares are, by definition, extremely small, but their aggregate energy release could represent a substantial heating mechanism, presuming they are sufficiently abundant. One way to test this presumption is via the flare frequency distribution, which describes how often flares of various energies occur. If the slope of the power law fitting the flare frequency distribution is above a critical threshold, $\alpha=2$ as established in prior literature, then there should be a sufficient abundance of nanoflares to explain coronal heating. We performed $>$600 case studies of solar flares, made possible by an unprecedented number of data analysts via three semesters of an undergraduate physics laboratory course. This allowed us to include two crucial, but nontrivial, analysis methods: pre-flare baseline subtraction and computation of the flare energy, which requires determining flare start and stop times. We aggregated the results of these analyses into a statistical study to determine that $\alpha = 1.63 \pm 0.03$. This is below the critical threshold, suggesting that Alfv\'en waves are an important driver of coronal heating., Comment: 1,002 authors, 14 pages, 4 figures, 3 tables, published by The Astrophysical Journal on 2023-05-09, volume 948, page 71
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- 2023
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142. Revisiting Takahashi's inversion theorem in discrete symmetry-based dual frameworks
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Rogerio, R. J. Bueno, Cavalcanti, R. T., da Silva, J. M. Hoff, and Villalobos, C. H. Coronado
- Subjects
High Energy Physics - Theory ,Mathematical Physics - Abstract
The so-called Takahashi's \emph{Inversion Theorem}, the reconstruction of a given spinor based on its bilinear covariants, are re-examined, considering alternative dual structures. In contrast to the classical results, where the Dirac dual structure plays the central role, new duals are built using the discrete symmetries $\mathcal{C}, \mathcal{P}, \mathcal{T}$. Their combinations are also taken into account. Furthermore, the imposition of a new adjoint structure led us also to re-examine the representation of the Clifford algebra basis elements, uncovering new bilinear structures and a new Fierz aggregate. Those results might help construct theories for new beyond standard model fields., Comment: 7 pages
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- 2023
- Full Text
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143. Impact of cross-section uncertainties on supernova neutrino spectral parameter fitting in the Deep Underground Neutrino Experiment
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DUNE Collaboration, Abud, A. Abed, Abi, B., Acciarri, R., Acero, M. A., Adames, M. R., Adamov, G., Adamowski, M., Adams, D., Adinolfi, M., Adriano, C., Aduszkiewicz, A., Aguilar, J., Ahmad, Z., Ahmed, J., Aimard, B., Akbar, F., Allison, K., Monsalve, S. Alonso, Alrashed, M., Alton, A., Alvarez, R., Amedo, P., Anderson, J., Andrade, D. A., Andreopoulos, C., Andreotti, M., Andrews, M. P., Andrianala, F., Andringa, S., Anfimov, N., Campanelli, W. L. Anicézio, Ankowski, A., Antoniassi, M., Antonova, M., Antoshkin, A., Aranda-Fernandez, A., Arellano, L., Arnold, L. O., Arroyave, M. A., Asaadi, J., Ashkenazi, A., Asquith, L., Atkin, E., Auguste, D., Aurisano, A., Aushev, V., Autiero, D., Ayala-Torres, M., Azfar, F., Back, A., Back, H., Back, J. J., Bagaturia, I., Bagby, L., Balashov, N., Balasubramanian, S., Baldi, P., Baldini, W., Baller, B., Bambah, B., Banerjee, R., Barao, F., Barenboim, G., Alzás, P. Barham, Barker, G. J., Barkhouse, W., Barnes, C., Barr, G., Monarca, J. Barranco, Barros, A., Barros, N., Barrow, J. L., Basharina-Freshville, A., Bashyal, A., Basque, V., Batchelor, C., Battat, J. B. R., Battisti, F., Bay, F., Bazetto, M. C. Q., Alba, J. L. L. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Belchior, E., Bell, G., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Benekos, N., Montiel, C. Benitez, Benjamin, D., Neves, F. Bento, Berger, J., Berkman, S., Bernardini, P., Berner, R. M., Bersani, A., Bertolucci, S., Betancourt, M., Rodríguez, A. Betancur, Bevan, A., Bezawada, Y., Bezerra, A. T., Bezerra, T. J., Bhambure, J., Bhardwaj, A., Bhatnagar, V., Bhattacharjee, M., Bhattacharya, M., Bhattarai, D., Bhuller, S., Bhuyan, B., Biagi, S., Bian, J., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Blaszczyk, F. D., Blazey, G. C., Blend, D., Blucher, E., Boissevain, J., Bolognesi, S., Bolton, T., Bomben, L., Bonesini, M., Bonilla-Diaz, C., Bonini, F., Booth, A., Boran, F., Bordoni, S., Borkum, A., Bostan, N., Bour, P., Bracinik, J., Braga, D., Brailsford, D., Branca, A., Brandt, A., Bravo-Moreno, M., Bremer, J., Brew, C., Brice, S. J., Brio, V., Brizzolari, C., Bromberg, C., Brooke, J., Bross, A., Brunetti, G., Brunetti, M., Buchanan, N., Budd, H., Buergi, J., V., G. Caceres, Cagnoli, I., Cai, T., Caiulo, D., Calabrese, R., Calafiura, P., Calcutt, J., Calin, M., Calivers, L., Calvez, S., Calvo, E., Caminata, A., Benitez, A. Campos, Caratelli, D., Carber, D., Carceller, J. M., Carini, G., Carlus, B., Carneiro, M. F., Carniti, P., Terrazas, I. Caro, Carranza, H., Carrara, N., Carroll, L., Carroll, T., Carter, A., Forero, J. F. Castaño, Castillo, A., Castromonte, C., Catano-Mur, E., Cattadori, C., Cavalier, F., Cavallaro, G., Cavanna, F., Centro, S., Cerati, G., Cervelli, A., Villanueva, A. Cervera, Chakraborty, K., Chalifour, M., Chappell, A., Chardonnet, E., Charitonidis, N., Chatterjee, A., Chattopadhyay, S., Chen, H., Chen, M., Chen, Y., Chen-Wishart, Z., Cheon, Y., Cherdack, D., Chi, C., Childress, S., Chirco, R., Chiriacescu, A., Chitirasreemadam, N., Cho, K., Choate, S., Chokheli, D., Chong, P. S., Chowdhury, B., Christensen, A., Christian, D., Christodoulou, G., Chukanov, A., Chung, M., Church, E., Cicero, V., Clapa, D., Clarke, P., Cline, G., Coan, T. E., Cocco, A. G., Coelho, J. A. B., Cohen, A., Collot, J., Conley, E., Conrad, J. M., Convery, M., Cooke, P., Copello, S., Cova, P., Cox, C., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Crisler, M., Cristaldo, E., Crnkovic, J., Crone, G., Cross, R., Cudd, A., Cuesta, C., Cui, Y., Cussans, D., Dai, J., Dalager, O., Dallavalle, R., da Motta, H., Dar, Z. A., Darby, R., Peres, L. Da Silva, David, C., David, Q., Davies, G. S., Davini, S., Dawson, J., De, K., De, S., De Aguiar, R., De Almeida, P., Debbins, P., De Bonis, I., Decowski, M. P., de Gouvêa, A., De Holanda, P. C., Astiz, I. L. De Icaza, Deisting, A., De Jong, P., De la Torre, A., Delbart, A., De Leo, V., Delepine, D., Delgado, M., Dell'Acqua, A., Delmonte, N., De Lurgio, P., Neto, J. R. T. de Mello, DeMuth, D. M., Dennis, S., Densham, C., Denton, P., Deptuch, G. W., De Roeck, A., De Romeri, V., De Souza, G., Detje, J. P., Devi, R., Devine, J., Dharmapalan, R., Dias, M., Díaz, J. S., Díaz, F., Di Capua, F., Di Domenico, A., Di Domizio, S., Di Falco, S., Di Giulio, L., Ding, P., Di Noto, L., Diociaiuti, E., Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Doering, D., Dolan, S., Dolek, F., Dolinski, M. J., Domenici, D., Domine, L., Donati, S., Donon, Y., Doran, S., Douglas, D., Dragone, A., Drielsma, F., Duarte, L., Duchesneau, D., Duffy, K., Dugas, K., Dunne, P., Dutta, B., Duyang, H., Dvornikov, O., Dwyer, D. A., Dyshkant, A. S., Eads, M., Earle, A., Edayath, S., Edmunds, D., Eisch, J., Emberger, L., Englezos, P., Ereditato, A., Erjavec, T., Escobar, C. O., Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Fajt, L., Falcone, A., Fani', M., Farnese, C., Farzan, Y., Fedoseev, D., Felix, J., Feng, Y., Fernandez-Martinez, E., Ferraro, F., Ferry, G., Fields, L., Filip, P., Filkins, A., Filthaut, F., Fine, R., Fiorillo, G., Fiorini, M., Fischer, V., Fitzpatrick, R. S., Flanagan, W., Fleming, B., Fogarty, S., Foreman, W., Fowler, J., Franc, J., Francis, K., Franco, D., Freeman, J., Fried, J., Friedland, A., Fuess, S., Furic, I. K., Furman, K., Furmanski, A. P., Gabrielli, A., Gago, A., Gallagher, H., Gallas, A., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Ganacim, F., Gandhi, R., Ganguly, S., Gao, F., Gao, S., Garcia-Gamez, D., García-Peris, M. Á., Gardiner, S., Gastler, D., Gauch, A., Gauvreau, J., Gauzzi, P., Ge, G., Geffroy, N., Gelli, B., Gent, S., Gerlach, L., Ghorbani-Moghaddam, Z., Giammaria, P., Giammaria, T., Giangiacomi, N., Gibin, D., Gil-Botella, I., Gilligan, S., Gioiosa, A., Giovannella, S., Girerd, C., Giri, A. K., Giugliano, C., Gnani, D., Gogota, O., Gollapinni, S., Gollwitzer, K., Gomes, R. A., Bermeo, L. V. Gomez, Fajardo, L. S. Gomez, Gonnella, F., Gonzalez-Diaz, D., Gonzalez-Lopez, M., Goodman, M. C., Goodwin, O., Goswami, S., Gotti, C., Goudeau, J., Goudzovski, E., Grace, C., Gran, R., Granados, E., Granger, P., Grant, C., Gratieri, D., Green, P., Greenberg, S., Greenler, L., Greer, J., Grenard, J., Griffith, W. C., Groetschla, F. T., Groh, M., Grzelak, K., Gu, W., Guarino, V., Guarise, M., Guenette, R., Guerard, E., Guerzoni, M., Guffanti, D., Guglielmi, A., Guo, B., Guo, Y., Gupta, A., Gupta, V., Guthikonda, K. K., Gutierrez, D., Guzowski, P., Guzzo, M. M., Gwon, S., Ha, C., Haaf, K., Habig, A., Hadavand, H., Haenni, R., Hagaman, L., Hahn, A., Haiston, J., Hamacher-Baumann, P., Hamernik, T., Hamilton, P., Han, J., Hancock, J., Happacher, F., Harris, D. A., Hartnell, J., Hartnett, T., Harton, J., Hasegawa, T., Hasnip, C., Hatcher, R., Hatfield, K. W., Hatzikoutelis, A., Hayes, C., Hayrapetyan, K., Hays, J., Hazen, E., He, M., Heavey, A., Heeger, K. M., Heise, J., Henry, S., Morquecho, M. A. Hernandez, Herner, K., Hewes, V., Higuera, A., Hilgenberg, C., Hill, T., Hillier, S. J., Himmel, A., Hinkle, E., Hirsch, L. R., Ho, J., Hoff, J., Holin, A., Holvey, T., Hoppe, E., Horton-Smith, G. A., Hostert, M., Houdy, T., Howard, B., Howell, R., Barrios, J. Hoyos, Hristova, I., Hronek, M. S., Huang, J., Huang, R. G., Hulcher, Z., Iles, G., Ilic, N., Iliescu, A. M., Illingworth, R., Ingratta, G., Ioannisian, A., Irwin, B., Isenhower, L., Oliveira, M. Ismerio, Itay, R., Jackson, C. M., Jain, V., James, E., Jang, W., Jargowsky, B., Jediny, F., Jena, D., Jeong, Y. S., Jesús-Valls, C., Ji, X., Jiang, J., Jiang, L., Jipa, A., Jo, J. H., Joaquim, F. R., Johnson, W., Jones, B., Jones, R., Jovancevic, N., Judah, M., Jung, C. K., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A., Kadenko, I., Kakorin, I., Kalitkina, A., Kalra, D., Koseyan, O. Kamer, Kamiya, F., Kaplan, D. M., Karagiorgi, G., Karaman, G., Karcher, A., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Katsioulas, I., Kauther, A., Kazaryan, N., Kearns, E., Keener, P. T., Kelly, K. J., Kemp, E., Kemularia, O., Kermaidic, Y., Ketchum, W., Kettell, S. H., Khabibullin, M., Khan, N., Khotjantsev, A., Khvedelidze, A., Kim, D., Kim, J., King, B., Kirby, B., Kirby, M., Klein, J., Kleykamp, J., Klustova, A., Kobilarcik, T., Koch, L., Koehler, K., Koerner, L. W., Koh, D. H., Kohn, S., Koller, P. P., Kolupaeva, L., Korablev, D., Kordosky, M., Kosc, T., Kose, U., Kostelecký, V. A., Kothekar, K., Kotler, I., Kozhukalov, V., Kralik, R., Kreczko, L., Krennrich, F., Kreslo, I., Kropp, W., Kroupova, T., Kubota, S., Kubu, M., Kudenko, Y., Kudryavtsev, V. A., Kuhlmann, S., Kulagin, S., Kumar, J., Kumar, P., Kunze, P., Kuravi, R., Kurita, N., Kuruppu, C., Kus, V., Kutter, T., Kvasnicka, J., Kwak, D., Labree, T., Lambert, A., Land, B. J., Lane, C. E., Lang, K., Langford, T., Langstaff, M., Lanni, F., Lantwin, O., Larkin, J., Lasorak, P., Last, D., Laundrie, A., Laurenti, G., Lawrence, A., Laycock, P., Lazanu, I., Lazzaroni, M., Le, T., Leardini, S., Learned, J., LeBrun, P., LeCompte, T., Lee, C., Legin, V., Miotto, G. Lehmann, Lehnert, R., de Oliveira, M. A. Leigui, Leitner, M., Lepin, L. M., Li, S. W., Li, Y., Liao, H., Lin, C. S., Lin, S., Lindebaum, D., Lineros, R. A., Ling, J., Lister, A., Littlejohn, B. R., Liu, J., Liu, Y., Lockwitz, S., Loew, T., Lokajicek, M., Lomidze, I., Long, K., March, N. López, Lord, T., LoSecco, J. M., Louis, W. C., Lu, X. -G., Luk, K. 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L., Radeka, V., Rademacker, J., Radev, R., Radics, B., Rafique, A., Raguzin, E., Rai, M., Rajaoalisoa, M., Rakhno, I., Rakotondravohitra, L., Rameika, R., Delgado, M. A. Ramirez, Ramson, B., Rappoldi, A., Raselli, G., Ratoff, P., Ray, R., Razafinime, H., Razakamiandra, R. F., Rea, E. M., Real, J. S., Rebel, B., Rechenmacher, R., Reggiani-Guzzo, M., Reichenbacher, J., Reitzner, S. D., Sfar, H. Rejeb, Renshaw, A., Rescia, S., Resnati, F., Ribas, M., Riboldi, S., Riccio, C., Riccobene, G., Rice, L. C. J., Ricol, J. S., Rigamonti, A., Rigan, M., Rincón, E. V., Ritchie-Yates, A., Ritter, S., Rivera, D., Rivera, R., Robert, A., Rocha, J. L. Rocabado, Rochester, L., Roda, M., Rodrigues, P., Alonso, M. J. Rodriguez, Rondon, J. Rodriguez, Rosauro-Alcaraz, S., Rosier, P., Rossella, M., Rossi, M., Ross-Lonergan, M., Rout, J., Roy, P., Rubbia, C., Ferreira, G. Ruiz, Russell, B., Ruterbories, D., Rybnikov, A., Saa-Hernandez, A., Saakyan, R., Sacerdoti, S., Sahoo, S. 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L., Snopok, P., Snowden-Ifft, D., Nunes, M. Soares, Sobel, H., Soderberg, M., Sokolov, S., Salinas, C. J. Solano, Söldner-Rembold, S., Soleti, S. R., Solomey, N., Solovov, V., Sondheim, W. E., Sorel, M., Sotnikov, A., Soto-Oton, J., Sousa, A., Soustruznik, K., Spagliardi, F., Spanu, M., Spitz, J., Spooner, N. J. C., Spurgeon, K., Stalder, D., Stancari, M., Stanco, L., Steenis, J., Stein, R., Steiner, H. M., Lisbôa, A. F. Steklain, Stepanova, A., Stewart, J., Stillwell, B., Stock, J., Stocker, F., Stokes, T., Strait, M., Strauss, T., Strigari, L., Stuart, A., Suarez, J. G., Subash, J., Surdo, A., Suter, L., Sutera, C. M., Sutton, K., Suvorov, Y., Svoboda, R., Swain, S. K., Szczerbinska, B., Szelc, A. M., Taffara, A., Talukdar, N., Tamara, J., Tanaka, H. A., Tang, S., Taniuchi, N., Oregui, B. Tapia, Tapper, A., Tariq, S., Tarpara, E., Tatar, E., Tayloe, R., Teklu, A. M., Tennessen, P., Tenti, M., Terao, K., Terranova, F., Testera, G., Thakore, T., Thea, A., Thompson, A., Thorn, C., Timm, S. C., Tishchenko, V., Todorović, N., Tomassetti, L., Tonazzo, A., Torbunov, D., Torti, M., Tortola, M., Tortorici, F., Tosi, N., Totani, D., Toups, M., Touramanis, C., Travaglini, R., Trevor, J., Trilov, S., Trzaska, W. H., Tsai, Y., Tsai, Y. -T., Tsamalaidze, Z., Tsang, K. V., Tsverava, N., Tu, S. Z., Tufanli, S., Tull, C., Turner, J., Tuzi, M., Tyler, J., Tyley, E., Tzanov, M., Uchida, M. A., Urheim, J., Usher, T., Utaegbulam, H., Uzunyan, S., Vagins, M. R., Vahle, P., Valder, S., Valdiviesso, G. D. A., Valencia, E., Valentim, R., Vallari, Z., Vallazza, E., Valle, J. W. F., Vallecorsa, S., Van Berg, R., Van de Water, R. G., Forero, D. Vanegas, Varanini, F., Oliva, D. Vargas, Varner, G., Vasina, S., Vaughan, N., Vaziri, K., Vega, J., Ventura, S., Verdugo, A., Vergani, S., Vermeulen, M. A., Verzocchi, M., Vicenzi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Viren, B., Vizcaya-Hernandez, A., Vrba, T., Vuong, Q., Waldron, A. V., Wallbank, M., Walsh, J., Walton, T., Wang, H., Wang, J., Wang, L., Wang, M. H. L. S., Wang, X., Wang, Y., Warburton, K., Warner, D., Wascko, M. O., Waters, D., Watson, A., Wawrowska, K., Weatherly, P., Weber, A., Weber, M., Wei, H., Weinstein, A., Wenman, D., Wetstein, M., Whilhelmi, J., White, A., Whitehead, L. H., Whittington, D., Wilking, M. J., Wilkinson, A., Wilkinson, C., Williams, Z., Wilson, F., Wilson, R. J., Wisniewski, W., Wolcott, J., Wolfs, J., Wongjirad, T., Wood, A., Wood, K., Worcester, E., Worcester, M., Wospakrik, M., Wresilo, K., Wret, C., Wu, S., Wu, W., Wurm, M., Wyenberg, J., Xiao, Y., Xiotidis, I., Yaeggy, B., Yahlali, N., Yandel, E., Yang, G., Yang, K., Yang, T., Yankelevich, A., Yershov, N., Yonehara, K., Yoon, Y. S., Young, T., Yu, B., Yu, H., Yu, J., Yu, Y., Yuan, W., Zaki, R., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zazueta, L., Zeller, G. P., Zennamo, J., Zeug, K., Zhang, C., Zhang, S., Zhang, Y., Zhao, M., Zhivun, E., Zimmerman, E. D., Zucchelli, S., Zuklin, J., Zutshi, V., and Zwaska, R.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Nuclear Theory - Abstract
A primary goal of the upcoming Deep Underground Neutrino Experiment (DUNE) is to measure the $\mathcal{O}(10)$ MeV neutrinos produced by a Galactic core-collapse supernova if one should occur during the lifetime of the experiment. The liquid-argon-based detectors planned for DUNE are expected to be uniquely sensitive to the $\nu_e$ component of the supernova flux, enabling a wide variety of physics and astrophysics measurements. A key requirement for a correct interpretation of these measurements is a good understanding of the energy-dependent total cross section $\sigma(E_\nu)$ for charged-current $\nu_e$ absorption on argon. In the context of a simulated extraction of supernova $\nu_e$ spectral parameters from a toy analysis, we investigate the impact of $\sigma(E_\nu)$ modeling uncertainties on DUNE's supernova neutrino physics sensitivity for the first time. We find that the currently large theoretical uncertainties on $\sigma(E_\nu)$ must be substantially reduced before the $\nu_e$ flux parameters can be extracted reliably: in the absence of external constraints, a measurement of the integrated neutrino luminosity with less than 10\% bias with DUNE requires $\sigma(E_\nu)$ to be known to about 5%. The neutrino spectral shape parameters can be known to better than 10% for a 20% uncertainty on the cross-section scale, although they will be sensitive to uncertainties on the shape of $\sigma(E_\nu)$. A direct measurement of low-energy $\nu_e$-argon scattering would be invaluable for improving the theoretical precision to the needed level., Comment: 25 pages, 21 figures
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- 2023
- Full Text
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144. Notes on the value function approach to multiobjective bilevel optimization
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Hoff, Daniel and Mehlitz, Patrick
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Mathematics - Optimization and Control ,49J52, 49J53, 90C29, 90C30 - Abstract
This paper is concerned with the value function approach to multiobjective bilevel optimization which exploits a lower level frontier-type mapping in order to replace the hierarchical model of two interdependent multiobjective optimization problems by a single-level multiobjective optimization problem. As a starting point, different value-function-type reformulations are suggested and their relations are discussed. Here, we focus on the situations where the lower level problem is solved up to efficiency or weak efficiency, and an intermediate solution concept is suggested as well. We study the graph-closedness of the associated efficiency-type and frontier-type mappings. These findings are then used for two purposes. First, we investigate existence results in multiobjective bilevel optimization. Second, for the derivation of necessary optimality conditions via the value function approach, it is inherent to differentiate frontier-type mappings in a generalized way. Here, we are concerned with the computation of upper coderivative estimates for the frontier-type mapping associated with the setting where the lower level problem is solved up to weak efficiency. We proceed in two ways, relying, on the one hand, on a weak domination property and, on the other hand, on a scalarization approach. Throughout the paper, illustrative examples visualize our findings, the necessity of crucial assumptions, and some flaws in the related literature., Comment: 32 pages
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- 2023
145. Suppression of Richtmyer-Meshkov instability via special pairs of shocks and phase transitions
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Schill, W. J., Armstrong, M. R., Nguyen, J. H., Sterbentz, D. M., White, D. A., Benedict, L. X., Rieben, R. N., Hoff, A., Lorenzana, H. E., La Lone, B. M., Staska, M. D., and Belof, J. L.
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Physics - Fluid Dynamics ,Condensed Matter - Other Condensed Matter - Abstract
The classical Richtmyer-Meshkov instability is a hydrodynamic instability characterizing the evolution of an interface following shock loading. In contrast to other hydrodynamic instabilities such as Rayleigh-Taylor, it is known for being unconditionally unstable: regardless of the direction of shock passage, any deviations from a flat interface will be amplified. In this article, we show that for negative Atwood numbers, there exist special sequences of shocks which result in a nearly perfectly suppressed instability growth. We demonstrate this principle computationally and experimentally with stepped fliers and phase transition materials. A fascinating immediate corollary is that in specific instances a phase transitioning material may self-suppress RMI.
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- 2023
146. Interest-Ability Profiles: An Integrative Approach to Knowledge Acquisition
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Hyland, William E., Hoff, Kevin A., and Rounds, James
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Cognitive abilities and interests both play an important role in guiding knowledge acquisition, but most previous studies have examined them separately. The current study used a large and representative dataset to integrate interests and abilities using a person-centered approach that examines how distinct profiles of interests and abilities relate to individual strengths and weaknesses in knowledge. Two key findings emerged. First, eight interest-ability profiles were generated from Latent Profile Analysis (LPA), which replicated and extended the interrelations of interests and abilities found in previous studies using variable-centered approaches. Second, each profile's strongest knowledge scores corresponded to their strongest abilities and interests, highlighting the importance of interest-ability profiles for guiding the development of knowledge. Importantly, in some domains, the lower ability profiles were actually more knowledgeable than higher ability profiles. Overall, these findings suggest that people learn best when given opportunities to acquire knowledge relevant to both their interests and abilities. We discuss how interest--ability profiles inform integrative theories of psychological development and present implications for education and career development.
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- 2022
147. The Effects of Vibration Signal Devices on Motivating Struggling Secondary Students to Write Longer and Better Stories
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Vilz, Delia, Barwasser, Anne, Hoff, Susanne, and Grünke, Matthias
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Writing is considered the most arduous academic task in school. Many students struggle with motivating themselves to engage in text production due to the enormous cognitive load it requires. In this pilot study, we used a simple electronic device that emits silent vibration signals at programmed intervals to help five sixth graders to stay focused on their writing assignments. All participants had limited academic abilities and found it hard to stay on task. We applied a single-case reversal design (ABA) to test the efficacy of the intervention. Results indicated that the students wrote considerably longer stories whenever the electronic devices were used. In addition, the quality of their texts increased as assessed by two independent raters. The findings beg for replication and more research on the topic, as this was the first study on using vibration signal devices to foster writing performance in struggling students.
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- 2022
148. 'It's a Different World': Language Ideologies, Literacies, and College Readiness
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Hoff, Meagan A. and Reynolds, Jessica S.
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For linguistically diverse students, the path to college is often defined by language. Depending on assessments and institutional policies, students may be placed into course sequences in developmental English, adult basic education, and/or English as a Second Language courses. The purpose of this study was to better understand developmental education, adult basic education, and English as a Second Language instructors' perceptions of how to best prepare linguistically diverse students for the literacy expectations of college courses. Ten instructors from Texas institutions were interviewed. Finding showed an overall lack of shared understandings of academic literacy across the three fields. Furthermore, there were tendencies towards deficit framings among developmental English instructors. Finally, findings showed a high level of animosity, particularly between English as a Second Language and developmental English instructors. Implications of these findings are discussed.
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- 2022
149. Bayesian Covariance Estimation for Multi-group Matrix-variate Data
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Bersson, Elizabeth and Hoff, Peter D.
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Statistics - Methodology - Abstract
Multi-group covariance estimation for matrix-variate data with small within group sample sizes is a key part of many data analysis tasks in modern applications. To obtain accurate group-specific covariance estimates, shrinkage estimation methods which shrink an unstructured, group-specific covariance either across groups towards a pooled covariance or within each group towards a Kronecker structure have been developed. However, in many applications, it is unclear which approach will result in more accurate covariance estimates. In this article, we present a hierarchical prior distribution which flexibly allows for both types of shrinkage. The prior linearly combines shrinkage across groups towards a shared pooled covariance and shrinkage within groups towards a group-specific Kronecker covariance. We illustrate the utility of the proposed prior in speech recognition and an analysis of chemical exposure data., Comment: 28 pages, 7 figures, 5 tables
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- 2023
150. Emergent spinor fields from exotic spin structures
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da Silva, J. M. Hoff and da Rocha, R.
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High Energy Physics - Theory ,Mathematical Physics - Abstract
The classification of emergent spinor fields according to modified bilinear covariants is scrutinized, in spacetimes with nontrivial topology, which induce inequivalent spin structures. Extended Clifford algebras, constructed by equipping the underlying spacetime with an extended bilinear form with additional terms coming from the nontrivial topology, naturally yield emergent extended algebraic spinor fields and their subsequent extended bilinear covariants, which are contrasted to the classical spinor classification. An unexpected duality between the standard and the exotic spinor field classes is therefore established, showing that a complementary fusion process among the spinor field classes sets in, when extended Clifford bundles are addressed in multiply-connected spacetimes., Comment: 16 pages, 2 figures; final version published in PTEP
- Published
- 2023
- Full Text
- View/download PDF
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