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4 results on '"Illario, Maddalena"'

1. Can Integrated Care Help in Meeting the Challenges Posed on Our Health Care Systems by COVID-19? Some Preliminary Lessons Learned from the European VIGOUR Project

Author

Lindner, Sonja, Kubitschke, Lutz, Lionis, Christos, Anastasaki, Marilena, Kirchmayer, Ursula, Giacomini, Simona, De Luca, Vincenzo, Iaccarino, Guido, Illario, Maddalena, Maddalena, Antonio, Maritati, Antonio, Conforti, Diego, Roba, Isabella, Musian, Daniele, Cano, Antonio, Granell, Monica, Carriazo, Ana M., Lama, Carmen M., Rodríguez, Susana, Guligowska, Agnieszka, Kostka, Tomasz, Konijnendijk, Annemieke, Vitullo, Maria, Garcia-Rudolph, Alejandro, Sánchez, Javier Solana, Maggio, Marcello, Liotta, Giuseppe, Tziraki, Chariklia, Roller-Wirnsberger, Regina, Universitat Autònoma de Barcelona, Biomedical Signals and Systems, Lindner, S., Kubitschke, L., Lionis, C., Anastasaki, M., Kirchmayer, U., Giacomini, S., De Luca, V., Iaccarino, G., Illario, M., Maddalena, A., Maritati, A., Conforti, D., Roba, I., Musian, D., Cano, A., Granell, M., Carriazo, A. M., Lama, C. M., Rodriguez, S., Guligowska, A., Kostka, T., Konijnendijk, A., Vitullo, M., Garcia-Rudolph, A., Sanchez, J. S., Maggio, M., Liotta, G., Tziraki, C., and Roller-Wirnsberger, R.

Subjects
Health (social science), Evidence-based practice, Sociology and Political Science, Coronavirus disease 2019 (COVID-19), 030231 tropical medicine, Context (language use), Pandemic management, 03 medical and health sciences, 0302 clinical medicine, Perspective Paper, Political science, Health care, Pandemic, pandemic management, media_common.cataloged_instance, 030212 general & internal medicine, Vulnerable patients, European union, integrated care, media_common, lcsh:R5-920, business.industry, Social care, Health Policy, Integrated care, COVID-19, vulnerable patients, Public relations, health care, social care, Work (electrical), Settore MED/42, lcsh:Medicine (General), business
Abstract

The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different systems making use of nested integrated care approaches adapted during the work of the EU-funded project VIGOUR ("Evidence based Guidance to Scale-up Integrated Care in Europe", funded by the European Union's Health Programme 2014-2020 under Grant Agreement Number 826640).

Published
2020

2. Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Author

Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi A., Blain, Hubert, Canonica, G. Walter, Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-Linnemann, Désirée, Mullol, Joaquim, and Papadopoulos, Nikos G.

Subjects
COVID-19, ANGIOTENSIN converting enzyme, FOOD habits, ANIMAL nutrition, REGIONAL differences
Abstract

Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit. [ABSTRACT FROM AUTHOR]

Published
2020
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3. Correction to: Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Author

Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi A., Blain, Hubert, Walter Canonica, G., Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas‑Linnemann, Désirée, Mullol, Joaquim, and Papadopoulos, Nikos G.

Subjects
COVID-19, ANIMAL nutrition, COUNTRIES
Abstract

An amendment to this paper has been published and can be accessed via the original article. [ABSTRACT FROM AUTHOR]

Published
2020
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4. Age and Multimorbidity Predict Death Among COVID-19 Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension

Author

Guido Iaccarino, Guido Grassi, Claudio Borghi, Claudio Ferri, Massimo Salvetti, Massimo Volpe, Arrigo F.G. Cicero, Pietro Minuz, Maria Lorenza Muiesan, Paolo Mulatero, Giuseppe Mulè, Giacomo Pucci, Carmine Savoia, Leonardo Sechi, Stefano Carugo, Francesco Fallo, Cristina Giannattasio, Davide Grassi, Claudio Letizia, Stefano Perlini, Damiano Rizzoni, Riccardo Sarzani, Giuliano Tocci, Franco Veglio, Claudia Agabiti Rosei, Michele Bevilacqua, Valeria Bisogni, Michele Bombelli, Luca Bulfone, Flaminia Canichella, Giovanni Carpani, Massimo Catanuso, Giulia Chiarini, Fernando Chiumiento, Rosario Cianci, Franco Cipollini, Antonio Concistrè, Andrea Dalbeni, Roberto Alberto De Blasi, Carolina De Ciuceis, Raffaella Dell’Oro, Antonino Di Guardo, Santo Di Lorenzo, Monica Di Norcia, Roberto Ervo, Elisabetta Eula, Davide Fabbricatore, Elvira Fanelli, Cristiano Fava, Enzo Grasso, Alessandro Grimaldi, Maddalena Illario, Claudio Invernizzi, Elena Iraca, Federica Liegi, Paolo Malerba, Alessandro Maloberti, Costantino Mancusi, Giulia Molinari, Roberta Mussinelli, Anna Paini, Paola Pellimassi, Ornella Piazza, Roberto Pontremoli, Fosca Quarti Tevano, Franco Rabbia, Monica Rocco, Anna Sabena, Francesco Salinaro, Paola Schiavi, Maria Chiara Sgariglia, Francesco Spannella, Sara Tedeschi, Pierluigi Viale, Iaccarino, G, Grassi, G, Borghi, C, Ferri, C, Salvetti, M, Volpe, M, Iaccarino G., Grassi G., Borghi C., Ferri C., Salvetti M., Volpe M., Mule G., SARS-RAS Investigator, Iaccarino, Guido, Grassi, Guido, Borghi, Claudio, Ferri, Claudio, Salvetti, Massimo, Illario, Maddalena, Volpe, Massimo, and Iaccarino G, Grassi G, Borghi C, Ferri C, Salvetti M, Volpe M, Cicero AFG

Subjects
Male, Cross-sectional study, Angiotensin-Converting Enzyme Inhibitors, 030204 cardiovascular system & hematology, Renin-Angiotensin System, 0302 clinical medicine, 80 and over, Medicine, odds ratio, 030212 general & internal medicine, Viral, Young adult, Societies, Medical, Aged, 80 and over, COVID-19, hypertension, Italy, multimorbidity, Adolescent, Adult, Age Distribution, Age Factors, Aged, Angiotensin Receptor Antagonists, Coronavirus Infections, Cross-Sectional Studies, Female, Humans, Hypertension, Middle Aged, Multimorbidity, Pandemics, Pneumonia, Viral, Prognosis, Survival Rate, Young Adult, Betacoronavirus, Mortality rate, medicine.medical_specialty, 03 medical and health sciences, Internal medicine, Diabetes mellitus, Medical, Internal Medicine, Survival rate, business.industry, SARS-CoV-2, Odds ratio, Pneumonia, medicine.disease, Heart failure, business, Societies, Kidney disease
Abstract

Several factors have been proposed to explain the high death rate of the coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age and multimorbidity might be confounders. No sufficient data are available to demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy to verify whether renin-angiotensin system inhibitors are related to COVID-19 severe outcomes. We analyzed information from Italian patients diagnosed with COVID-19, admitted in 26 hospitals. One thousand five hundred ninety-one charts (male, 64.1%; 66±0.4 years) were recorded. At least 1 preexisting condition was observed in 73.4% of patients, with hypertension being the most represented (54.9%). One hundred eighty-eight deaths were recorded (11.8%; mean age, 79.6±0.9 years). In nonsurvivors, older age, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease, coronary artery diseases, and heart failure were more represented than in survivors. The Charlson Comorbidity Index was significantly higher in nonsurvivors compared with survivors (4.3±0.15 versus 2.6±0.05; P P =0.0001), diabetes mellitus ( P =0.004), chronic obstructive pulmonary disease ( P =0.011), and chronic kidney disease ( P =0.004) but not hypertension predicted mortality. Charlson Comorbidity Index, which cumulates age and comorbidities, predicts mortality with an exponential increase in the odds ratio by each point of score. In the COVID-19 outbreak, mortality is predicted by age and the presence of comorbidities. Our data do not support a significant interference of hypertension and antihypertensive therapy on COVID-19 lethality. Registration— URL: https://www.clinicaltrials.gov ; Unique identifier: NCT04331574.

Published
2020

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