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14 results on '"S Almenar"'

1. Anatomy, immunohistochemistry, and numerical distribution of human splenic microvessels

Author: Amparo Ruiz-Sauri, P. Molina, A. Ferrandez-Izquierdo, María Elena Olmos Ortega, S. Almenar, and Cesar Rios-Navarro
Subjects: 0301 basic medicine, Sialic Acid Binding Ig-like Lectin 1, CD8 Antigens, CD34, Immunoglobulins, Spleen, Antigens, CD34, 03 medical and health sciences, Mucoproteins, Trabecular veins, Reticular cell, medicine, Humans, Adapalene, Vein, Forensic Pathology, Sinus (anatomy), Venule, Chemistry, General Medicine, Anatomy, Immunohistochemistry, Actins, Platelet Endothelial Cell Adhesion Molecule-1, Arterioles, 030104 developmental biology, medicine.anatomical_structure, Microvessels, 030101 anatomy & morphology, Autopsy, Cell Adhesion Molecules, Splenic Artery, Developmental Biology
Abstract: The microvascular architecture of the spleen plays an important role in the immunological function of this organ. The different types of vessels are related to different reticular cells each with their own immunomodulatory functions. The present study describes an immunohistochemical and morphometric analysis of the various types of vessels in 21 human autopsy non-pathological splenic samples. On an area of 785,656.37 μm2 for each sample, we classified and quantified the type and number of vascular structures, each according to their morphology and immunohistochemical profile, and obtained the ratios between them. The distribution of trabecular vessels and the characteristics of the venules are reviewed. In our material the so-called “cavernous perimarginal sinus” (anatomical structure previously described by Schmidt et al., 1988) was observed and interpreted as a curvilinear venule shaped by the follicle in contact with the trabecular vein. Our material comprised 261 trabeculae (containing 269 arterial sections and 508 venous sections), 30,621 CD34+ capillaries, 7739 CD271+ sheathed capillaries, 2588 CD169+ sheathed capillaries, and 31,124 CD8+ sinusoids. The total area (TA) (14,765,714.88 μm2) occupied by the sinusoidal sections of the 21 cases was much higher than the TA of the capillary sections (1,700,269.83 μm2). Similarly, the TA (651,985 μm2) occupied by the sections of the trabecular veins was much higher than the TA of the trabecular arteries (88,594 μm2). The total number of CD34+ capillaries and of sinusoids CD8+ was similar for the sum of the 21 cases, nevertheless there were large differences in each case. Statistically the hypothesis that the number of capillaries and sinusoids are present with the same frequency is discarded. In view of the absence of a numerical correlation between capillaries and sinusoids, we postulate that very possibly the arterial and the venous vascular trees are two anatomically independent structures separated by the splenic cords. We believe that this is the first work where splenic microvascularization is simultaneously approached from a morphometric and immunohistochemical point of view.
Published: 2019

2. Microcystic Adnexal Carcinoma: Mohs Micrographic Surgery as the Treatment of Choice

Author: C. Requena-Caballero, B. Llombart-Cussac, Rafael Botella-Estrada, O. Sanmartín-Jiménez, Antonio Martorell-Calatayud, S. Almenar-Medina, C. Guillén-Barona, Carlos Serra-Guillén, E. Nagore-Enguídanos, and B. Echeverría-García
Subjects: medicine.medical_specialty, Histology, business.industry, Wide local excision, medicine.medical_treatment, Perineural invasion, Dermatology, medicine.disease, Primary tumor, Pathology and Forensic Medicine, Surgery, Subcutaneous nodule, Atypia, medicine, Mohs surgery, Basal cell carcinoma, business, Microcystic adnexal carcinoma
Abstract: Introduction and objectives Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck. The tumor can be confused clinically and histologically with other benign and malignant skin lesions, often leading to inappropriate initial treatment. The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision. Recent preliminary studies point to higher cure rates with Mohs micrographic surgery. Material and methods We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007. Results In all cases, lesions were located on the head and were primary tumors. Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma. Perineural invasion was not detected in any patient, and all were free of recurrence after between 1 and 12 years of postoperative follow-up. Conclusions The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors. This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence. The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma.
Published: 2009
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3. Carcinoma anexial microquístico: la cirugía micrográfica de Mohs como tratamiento de elección

Author: E. Nagore-Enguídanos, O. Sanmartín-Jiménez, C. Serra-Guillén, B. Llombart-Cussac, C. Requena-Caballero, C. Guillén-Barona, B. Echeverría-García, S. Almenar-Medina, Antonio Martorell-Calatayud, and R. Botella-Estrada
Subjects: medicine.medical_specialty, business.industry, Wide local excision, medicine.medical_treatment, Perineural invasion, General Medicine, medicine.disease, Primary tumor, Surgery, Subcutaneous nodule, Atypia, Medicine, Initial treatment, Basal cell carcinoma, business, Microcystic adnexal carcinoma
Abstract: Introduction and objectives. Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck. The tumor can be confused clinically and histologically with other benign and malignant skin lesions, often leading to inappropriate initial treatment. The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision. Recent preliminary studies point to higher cure rates with Mohs micrographic surgery. Material and methods. We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007. Results. In all cases, lesions were located on the head and were primary tumors. Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma. Perineural invasion was not detected in any patient, and all were free of recurrence after between 1 and 12 years of postoperative follow-up. Conclusions. The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors. This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence. The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma.
Published: 2009
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4. The ATLAS Inner Detector commissioning and calibration

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Pedrosa, F.B.S. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Guimarães da Costa, J.B. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Harpaz, S.B. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ami, S.B. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Kuutmann, E.B. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernabéu, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boehler, M. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Bordoni, S. Borer, C. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boveia, A. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, B. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brown, G. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. Burgess, T. Burke, S. Busato, E. Bussey, P. Buszello, C.P. Butin, F. Butler, B. Butler, J.M. Buttar, C.M. Butterworth, J.M. Byatt, T. Caballero, J. Cabrera Urbán, S. Caforio, D. Cakir, O. Calafiura, P. Calderini, G. Calfayan, P. Calkins, R. Caloba, L.P. Calvet, D. Camarri, P. Cameron, D. Campana, S. Campanelli, M. Canale, V. Canelli, F. Canepa, A. Cantero, J. Capasso, L. Garrido, M.D.M.C. Caprini, I. Caprini, M. Capua, M. Caputo, R. Caramarcu, C. Cardarelli, R. Carli, T. Carlino, G. Carminati, L. Caron, B. Caron, S. Montoya, G.D.C. Montero, S.C. Carter, A.A. Carter, J.R. Carvalho, J. Casadei, D. Casado, M.P. Cascella, M. Castaneda Hernandez, A.M. Castaneda-Miranda, E. Gimenez, V.C. Castro, N.F. Cataldi, G. Catinaccio, A. Catmore, J.R. Cattai, A. Cattani, G. Caughron, S. Cavalleri, P. Cavalli, D. Cavalli-Sforza, M. Cavasinni, V. Ceradini, F. Cerqueira, A.S. Cerri, A. Cerrito, L. Cerutti, F. Cetin, S.A. Chafaq, A. Chakraborty, D. Chan, K. Chapman, J.D. Chapman, J.W. Chareyre, E. Charlton, D.G. Chavda, V. Cheatham, S. Chekanov, S. Chekulaev, S.V. Chelkov, G.A. Chen, H. Chen, S. Chen, X. Cheplakov, A. Chepurnov, V.F. Cherkaoui El Moursli, R. Tcherniatine, V. Chesneanu, D. Cheu, E. Cheung, S.L. Chevalier, L. Chevallier, F. Chiefari, G. Chikovani, L. Childers, J.T. Chilingarov, A. Chiodini, G. Chizhov, V. Choudalakis, G. Chouridou, S. Christidi, I.A. Christov, A. Chromek-Burckhart, D. Chu, M.L. Chudoba, J. Ciapetti, G. Ciftci, A.K. Ciftci, R. Cinca, D. Cindro, V. Ciobotaru, M.D. Ciocca, C. Ciocio, A. Cirilli, M. Clark, A. Clark, P.J. Cleland, W. Clemens, J.C. Clement, B. Clement, C. Coadou, Y. Cobal, M. Coccaro, A. Cochran, J. Coggeshall, J. Cogneras, E. Colijn, A.P. Collard, C. Collins, N.J. Collins-Tooth, C. Collot, J. Colon, G. Conde Muiño, P. Coniavitis, E. Conidi, M.C. Consonni, M. Constantinescu, S. Conta, C. Conventi, F. Cooke, M. Cooper, B.D. Cooper-Sarkar, A.M. Cooper-Smith, N.J. Copic, K. Cornelissen, T. Corradi, M. Corriveau, F. Corso-Radu, A. Cortes-Gonzalez, A. Cortiana, G. Costa, G. Costa, M.J. Costanzo, D. Costin, T. Côté, D. Torres, R.C. Courneyea, L. Cowan, G. Cowden, C. Cox, B.E. Cranmer, K. Cranshaw, J. Cristinziani, M. Crosetti, G. Crupi, R. Crépé-Renaudin, S. Almenar, C.C. Donszelmann, T.C. Curatolo, M. Curtis, C.J. Cwetanski, P. Czyczula, Z. D'Auria, S. D'Onofrio, M. D'Orazio, A. Da Via, C. Dabrowski, W. Dai, T. Dallapiccola, C. Dallison, S.J. Daly, C.H. Dam, M. Danielsson, H.O. Dannheim, D. Dao, V. Darbo, G. Darlea, G.L. Davey, W. Davidek, T. Davidson, N. Davidson, R. Davies, M. Davison, A.R. Dawson, I. Daya, R.K. De, K. de Asmundis, R. De Castro, S. De Faria Salgado, P.E.C. De Cecco, S. de Graat, J. De Groot, N. de Jong, P. De Mora, L. De Branco, M.O. De Pedis, D. De Salvo, A. De Sanctis, U. De Santo, A. De Vivie De Regie, J.B. Dean, S. Dedovich, D.V. Degenhardt, J. Dehchar, M. Del Papa, C. Del Peso, J. Del Prete, T. Dell'Acqua, A. Dell'Asta, L. Della Pietra, M. della Volpe, D. Delmastro, M. Delsart, P.A. Deluca, C. Demers, S. Demichev, M. Demirkoz, B. Deng, J. Deng, W. Denisov, S.P. Derkaoui, J.E. Derue, F. Dervan, P. Desch, K. Deviveiros, P.O. Dewhurst, A. DeWilde, B. Dhaliwal, S. Dhullipudi, R. Di Ciaccio, A. Di Ciaccio, L. Di Girolamo, A. Di Girolamo, B. Di Luise, S. Di Mattia, A. Di Nardo, R. Di Simone, A. Di Sipio, R. Diaz, M.A. Diblen, F. Diehl, E.B. Dietrich, J. Dietzsch, T.A. Diglio, S. Yagci, K.D. Dingfelder, J. Dionisi, C. Dita, P. Dita, S. Dittus, F. Djama, F. Djilkibaev, R. Djobava, T. do Vale, M.A.B. Do Wemans, A.V. Doan, T.K.O. Dobos, D. Dobson, E. Dobson, M. Doglioni, C. Doherty, T. Dolejsi, J. Dolenc, I. Dolezal, Z. Dolgoshein, B.A. Dohmae, T. Donega, M. Donini, J. Dopke, J. Doria, A. Dos Anjos, A. Dotti, A. Dova, M.T. Doxiadis, A. Doyle, A.T. Drasal, Z. Dris, M. Dubbert, J. Duchovni, E. Duckeck, G. Dudarev, A. Dudziak, F. Dührssen, M. Duflot, L. Dufour, M.-A. Dunford, M. Yildiz, H.D. Duxfield, R. Dwuznik, M. Düren, M. Ebenstein, W.L. Ebke, J. Eckweiler, S. Edmonds, K. Edwards, C.A. Egorov, K. Ehrenfeld, W. Ehrich, T. Eifert, T. Eigen, G. Einsweiler, K. Eisenhandler, E. Ekelof, T. El Kacimi, M. Ellert, M. Elles, S. Ellinghaus, F. Ellis, K. Ellis, N. Elmsheuser, J. Elsing, M. Emeliyanov, D. Engelmann, R. Engl, A. Epp, B. Eppig, A. Erdmann, J. Ereditato, A. Eriksson, D. Ermoline, I. Ernst, J. Ernst, M. Ernwein, J. Errede, D. Errede, S. Ertel, E. Escalier, M. Escobar, C. Curull, X.E. Esposito, B. Etienvre, A.I. Etzion, E. Evans, H. Fabbri, L. Fabre, C. Facius, K. Fakhrutdinov, R.M. Falciano, S. Fang, Y. Fanti, M. Farbin, A. Farilla, A. Farley, J. Farooque, T. Farrington, S.M. Farthouat, P. Fassnacht, P. Fassouliotis, D. Fatholahzadeh, B. Fayard, L. Fayette, F. Febbraro, R. Federic, P. Fedin, O.L. Fedorko, W. Feligioni, L. Felzmann, C.U. Feng, C. Feng, E.J. Fenyuk, A.B. Ferencei, J. Ferland, J. Fernandes, B. Fernando, W. Ferrag, S. Ferrando, J. Ferrara, V. Ferrari, A. Ferrari, P. Ferrari, R. Ferrer, A. Ferrer, M.L. Ferrere, D. Ferretti, C. Fiascaris, M. Fiedler, F. Filipčič, A. Filippas, A. Filthaut, F. Fincke-Keeler, M. Fiolhais, M.C.N. Fiorini, L. Firan, A. Fischer, G. Fisher, M.J. Flechl, M. Fleck, I. Fleckner, J. Fleischmann, P. Fleischmann, S. Flick, T. Castillo, L.R.F. Flowerdew, M.J. Martin, T.F. Formica, A. Forti, A. Fortin, D. Fournier, D. Fowler, A.J. Fowler, K. Fox, H. Francavilla, P. Franchino, S. Francis, D. Franklin, M. Franz, S. Fraternali, M. Fratina, S. Freestone, J. French, S.T. Froeschl, R. Froidevaux, D. Frost, J.A. Fukunaga, C. Torregrosa, E.F. Fuster, J. Gabaldon, C. Gabizon, O. Gadfort, T. Gadomski, S. Gagliardi, G. Gagnon, P. Galea, C. Gallas, E.J. Gallo, V. Gallop, B.J. Gallus, P. Galyaev, E. Gan, K.K. Gao, Y.S. Gaponenko, A. Garcia-Sciveres, M. García, C. Navarro, J.E.G. Gardner, R.W. Garelli, N. Garitaonandia, H. Garonne, V. Gatti, C. Gaudio, G. Gautard, V. Gauzzi, P. Gavrilenko, I.L. Gay, C. Gaycken, G. Gazis, E.N. Ge, P. Gee, C.N.P. Geich-Gimbel, C. Gellerstedt, K. Gemme, C. Genest, M.H. Gentile, S. Georgatos, F. George, S. Gershon, A. Ghazlane, H. Ghodbane, N. Giacobbe, B. Giagu, S. Giakoumopoulou, V. Giangiobbe, V. Gianotti, F. Gibbard, B. Gibson, A. Gibson, S.M. Gilbert, L.M. Gilchriese, M. Gilewsky, V. Gingrich, D.M. Ginzburg, J. Giokaris, N. Giordani, M.P. Giordano, R. Giorgi, F.M. Giovannini, P. Giraud, P.F. Girtler, P. Giugni, D. Giusti, P. Gjelsten, B.K. Gladilin, L.K. Glasman, C. Glazov, A. Glitza, K.W. Glonti, G.L. Godfrey, J. Godlewski, J. Goebel, M. Göpfert, T. Goeringer, C. Gössling, C. Göttfert, T. Goggi, V. Goldfarb, S. Goldin, D. Golling, T. Gomes, A. Fajardo, L.S.G. Gonçalo, R. Gonella, L. Gong, C. González de la Hoz, S. Silva, M.L.G. Gonzalez-Sevilla, S. Goodson, J.J. Goossens, L. Gordon, H.A. Gorelov, I. Gorfine, G. Gorini, B. Gorini, E. Gorišek, A. Gornicki, E. Gosdzik, B. Gosselink, M. Gostkin, M.I. Eschrich, I.G. Gouighri, M. Goujdami, D. Goulette, M.P. Goussiou, A.G. Goy, C. Grabowska-Bold, I. Grafström, P. Grahn, K.-J. Grancagnolo, S. Grassi, V. Gratchev, V. Grau, N. Gray, H.M. Gray, J.A. Graziani, E. Green, B. Greenshaw, T. Greenwood, Z.D. Gregor, I.M. Grenier, P. Griesmayer, E. Griffiths, J. Grigalashvili, N. Grillo, A.A. Grimm, K. Grinstein, S. Grishkevich, Y.V. Groh, M. Groll, M. Gross, E. Grosse-Knetter, J. Groth-Jensen, J. Grybel, K. Guicheney, C. Guida, A. Guillemin, T. Guler, H. Gunther, J. Guo, B. Gusakov, Y. Gutierrez, A. Gutierrez, P. Guttman, N. Gutzwiller, O. Guyot, C. Gwenlan, C. Gwilliam, C.B. Haas, A. Haas, S. Haber, C. Hadavand, H.K. Hadley, D.R. Haefner, P. Hajduk, Z. Hakobyan, H. Haller, J. Hamacher, K. Hamilton, A. Hamilton, S. Han, L. Hanagaki, K. Hance, M. Handel, C. Hanke, P. Hansen, J.R. Hansen, J.B. Hansen, J.D. Hansen, P.H. Hansl-Kozanecka, T. Hansson, P. Hara, K. Hare, G.A. Harenberg, T. Harrington, R.D. Harris, O.M. Harrison, K. Hartert, J. Hartjes, F. Harvey, A. Hasegawa, S. Hasegawa, Y. Hassani, S. Haug, S. Hauschild, M. Hauser, R. Havranek, M. Hawkes, C.M. Hawkings, R.J. Hayakawa, T. Hayward, H.S. Haywood, S.J. Head, S.J. Hedberg, V. Heelan, L. Heim, S. Heinemann, B. Heisterkamp, S. Helary, L. Heller, M. Hellman, S. Helsens, C. Hemperek, T. Henderson, R.C.W. Henke, M. Henrichs, A. Correia, A.M.H. Henrot-Versille, S. Hensel, C. Henß, T. Jiménez, Y.H. Hershenhorn, A.D. Herten, G. Hertenberger, R. Hervas, L. Hessey, N.P. Higón-Rodriguez, E. Hill, J.C. Hiller, K.H. Hillert, S. Hillier, S.J. Hinchliffe, I. Hines, E. Hirose, M. Hirsch, F. Hirschbuehl, D. Hobbs, J. Hod, N. Hodgkinson, M.C. Hodgson, P. Hoecker, A. Hoeferkamp, M.R. Hoffman, J. Hoffmann, D. Hohlfeld, M. Holy, T. Holzbauer, J.L. Homma, Y. Horazdovsky, T. Hori, T. Horn, C. Horner, S. Horvat, S. Hostachy, J.-Y. Hou, S. Hoummada, A. Howe, T. Hrivnac, J. Hryn'ova, T. Hsu, P.J. Hsu, S.-C. Huang, G.S. Hubacek, Z. Hubaut, F. Huegging, F. Huffman, T.B. Hughes, E.W. Hughes, G. Hurwitz, M. Husemann, U. Huseynov, N. Huston, J. Huth, J. Iacobucci, G. Iakovidis, G. Ibragimov, I. Iconomidou-Fayard, L. Idarraga, J. Iengo, P. Igonkina, O. Ikegami, Y. Ikeno, M. Ilchenko, Y. Iliadis, D. Ince, T. Ioannou, P. Iodice, M. Quiles, A.I. 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Triplett, N. Trischuk, W. Trivedi, A. Trocmé, B. Troncon, C. Trzupek, A. Tsarouchas, C. Tseng, J.C.-L. Tsiakiris, M. Tsiareshka, P.V. Tsionou, D. Tsipolitis, G. Tsiskaridze, V. Tskhadadze, E.G. Tsukerman, I.I. Tsulaia, V. Tsung, J.-W. Tsuno, S. Tsybychev, D. Tuggle, J.M. Turecek, D. Cakir, I.T. Turlay, E. Tuts, P.M. Twomey, M.S. Tylmad, M. Tyndel, M. Uchida, K. Ueda, I. Ueno, R. Ugland, M. Uhlenbrock, M. Uhrmacher, M. Ukegawa, F. Unal, G. Undrus, A. Unel, G. Unno, Y. Urbaniec, D. Urkovsky, E. Urquijo, P. Urrejola, P. Usai, G. Uslenghi, M. Vacavant, L. Vacek, V. Vachon, B. Vahsen, S. Valente, P. Valentinetti, S. Valkar, S. Gallego, E.V. Vallecorsa, S. Ferrer, J.A.V. van Berg, R. van der Graaf, H. van der Kraaij, E. van der Poel, E. van der Ster, D. van Eldik, N. van Gemmeren, P. van Kesteren, Z. van Vulpen, I. Vandelli, W. Vaniachine, A. Vankov, P. Vannucci, F. Vari, R. Varnes, E.W. Varouchas, D. Vartapetian, A. Varvell, K.E. Vasilyeva, L. Vassilakopoulos, V.I. Vazeille, F. 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Subjects: Physics::Instrumentation and Detectors
Abstract: The ATLAS Inner Detector is a composite tracking system consisting of silicon pixels, silicon strips and straw tubes in a 2 T magnetic field. Its installation was completed in August 2008 and the detector took part in data-taking with single LHC beams and cosmic rays. The initial detector operation, hardware commissioning and in-situ calibrations are described. Tracking performance has been measured with 7. 6 million cosmic-ray events, collected using a tracking trigger and reconstructed with modular pattern-recognition and fitting software. The intrinsic hit efficiency and tracking trigger efficiencies are close to 100%. Lorentz angle measurements for both electrons and holes, specific energy-loss calibration and transition radiation turn-on measurements have been performed. Different alignment techniques have been used to reconstruct the detector geometry. After the initial alignment, a transverse impact parameter resolution of 22. 1±0. 9 μm and a relative momentum resolution σp/p=(4. 83±0. 16)×10-4 GeV-1×pT have been measured for high momentum tracks. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

5. Commissioning of the ATLAS Muon Spectrometer with cosmic rays

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahmed, H. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astbury, A. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Axen, D. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Santos Pedrosa, F.B. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Baranov, S. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Barreiro Guimarães da Costa, J. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Becerici, N. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Harpaz, S.B. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ben Ami, S. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benincasa, G.P. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Bergeaas Kuutmann, E. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Binet, S. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boehler, M. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Bordoni, S. Borer, C. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boveia, A. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandenburg, G.W. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, B. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brown, G. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. Burgess, T. Burke, S. Busato, E. Bussey, P. Buszello, C.P. Butin, F. Butler, B. Butler, J.M. Buttar, C.M. Butterworth, J.M. Byatt, T. Caballero, J. Cabrera Urbán, S. Caforio, D. Cakir, O. Calafiura, P. Calderini, G. Calfayan, P. Calkins, R. Caloba, L.P. Calvet, D. Camarri, P. Cameron, D. Campana, S. Campanelli, M. Canale, V. Canelli, F. Canepa, A. Cantero, J. Capasso, L. Capeans Garrido, M.D.M. Caprini, I. Caprini, M. Capua, M. Caputo, R. Caramarcu, C. Cardarelli, R. Carli, T. Carlino, G. Carminati, L. Caron, B. Caron, S. Carrillo Montoya, G.D. Carron Montero, S. Carter, A.A. Carter, J.R. Carvalho, J. Casadei, D. Casado, M.P. Cascella, M. Castaneda Hernandez, A.M. Castaneda-Miranda, E. Castillo Gimenez, V. Castro, N.F. Cataldi, G. Catinaccio, A. Catmore, J.R. Cattai, A. Cattani, G. Caughron, S. Cauz, D. Cavalleri, P. Cavalli, D. Cavalli-Sforza, M. Cavasinni, V. Ceradini, F. Cerqueira, A.S. Cerri, A. Cerrito, L. Cerutti, F. Cetin, S.A. Chafaq, A. Chakraborty, D. Chan, K. Chapman, J.D. 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Smakhtin, V. Smirnov, S.Y. Smirnov, Y. Smirnova, L.N. Smirnova, O. Smith, B.C. Smith, D. Smith, K.M. Smizanska, M. Smolek, K. Snesarev, A.A. Snow, S.W. Snow, J. Snuverink, J. Snyder, S. Soares, M. Sobie, R. Sodomka, J. Soffer, A. Solans, C.A. Solar, M. Solc, J. Camillocci, E.S. Solodkov, A.A. Solovyanov, O.V. Soluk, R. Sondericker, J. Sopko, V. Sopko, B. Sosebee, M. Soukharev, A. Spagnolo, S. Spanò, F. Spencer, E. Spighi, R. Spigo, G. Spila, F. Spiwoks, R. Spousta, M. Spreitzer, T. Spurlock, B. Denis, R.D.S. Stahl, T. Stahlman, J. Stamen, R. Stancu, S.N. Stanecka, E. Stanek, R.W. Stanescu, C. Stapnes, S. Starchenko, E.A. Stark, J. Staroba, P. Starovoitov, P. Stastny, J. Stavina, P. Steele, G. Steinbach, P. Steinberg, P. Stekl, I. Stelzer, B. Stelzer, H.J. Stelzer-Chilton, O. Stenzel, H. Stevenson, K. Stewart, G.A. Stockton, M.C. Stoerig, K. Stoicea, G. Stonjek, S. Strachota, P. Stradling, A.R. Straessner, A. Strandberg, J. Strandberg, S. Strandlie, A. Strauss, M. Strizenec, P. 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Aires Viegas, F.J.T. Tisserant, S. Toczek, B. Todorov, T. Todorova-Nova, S. Toggerson, B. Tojo, J. Tokár, S. Tokushuku, K. Tollefson, K. Tomasek, L. Tomasek, M. Tomoto, M. Tompkins, L. Toms, K. Tonoyan, A. Topfel, C. Topilin, N.D. Torrence, E. Pastor, E.T. Toth, J. Touchard, F. Tovey, D.R. Trefzger, T. Tremblet, L. Tricoli, A. Trigger, I.M. Trincaz-Duvoid, S. Trinh, T.N. Tripiana, M.F. Triplett, N. Trischuk, W. Trivedi, A. Trocmé, B. Troncon, C. Trzupek, A. Tsarouchas, C. Tseng, J.C.-L. Tsiakiris, M. Tsiareshka, P.V. Tsionou, D. Tsipolitis, G. Tsiskaridze, V. Tskhadadze, E.G. Tsukerman, I.I. Tsulaia, V. Tsung, J.-W. Tsuno, S. Tsybychev, D. Tuggle, J.M. Turecek, D. Cakir, I.T. Turlay, E. Tuts, P.M. Twomey, M.S. Tylmad, M. Tyndel, M. Uchida, K. Ueda, I. Ugland, M. Uhlenbrock, M. Uhrmacher, M. Ukegawa, F. Unal, G. Undrus, A. Unel, G. Unno, Y. Urbaniec, D. Urkovsky, E. Urquijo, P. Urrejola, P. Usai, G. Uslenghi, M. Vacavant, L. Vacek, V. Vachon, B. Vahsen, S. Valente, P. Valentinetti, S. 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Wright, D. Wrona, B. Wu, S.L. Wu, X. Wulf, E. Wynne, B.M. Xaplanteris, L. Xella, S. Xie, S. Xu, D. Xu, N. Yamada, M. Yamamoto, A. Yamamoto, K. Yamamoto, S. Yamamura, T. Yamaoka, J. Yamazaki, T. Yamazaki, Y. Yan, Z. Yang, H. Yang, U.K. Yang, Z. Yao, W.-M. Yao, Y. Yasu, Y. Ye, J. Ye, S. Yilmaz, M. Yoosoofmiya, R. Yorita, K. Yoshida, R. Young, C. Youssef, S.P. Yu, D. Yu, J. Yuan, L. Yurkewicz, A. Zaidan, R. Zaitsev, A.M. Zajacova, Z. Zambrano, V. Zanello, L. Zaytsev, A. Zeitnitz, C. Zeller, M. Zemla, A. Zendler, C. Zenin, O. Zenis, T. Zenonos, Z. Zenz, S. Zerwas, D. della Porta, G.Z. Zhan, Z. Zhang, H. Zhang, J. Zhang, Q. Zhang, X. Zhao, L. Zhao, T. Zhao, Z. Zhemchugov, A. Zhong, J. Zhou, B. Zhou, N. Zhou, Y. Zhu, C.G. Zhu, H. Zhu, Y. Zhuang, X. Zhuravlov, V. Zimmermann, R. Zimmermann, S. Zimmermann, S. Ziolkowski, M. Živković, L. Zobernig, G. Zoccoli, A. zur Nedden, M. Zutshi, V.
Subjects: Physics::Instrumentation and Detectors, Physics::Accelerator Physics, High Energy Physics::Experiment, Nuclear Experiment
Abstract: The ATLAS detector at the Large Hadron Collider has collected several hundred million cosmic ray events during 2008 and 2009. These data were used to commission the Muon Spectrometer and to study the performance of the trigger and tracking chambers, their alignment, the detector control system, the data acquisition and the analysis programs. We present the performance in the relevant parameters that determine the quality of the muon measurement. We discuss the single element efficiency, resolution and noise rates, the calibration method of the detector response and of the alignment system, the track reconstruction efficiency and the momentum measurement. The results show that the detector is close to the design performance and that the Muon Spectrometer is ready to detect muons produced in high energy proton-proton collisions. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

6. The ATLAS Simulation Infrastructure

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahmed, H. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astbury, A. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Axen, D. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Santos Pedrosa, F.B. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Baranov, S. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Guimarães da Costa, J.B. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Becerici, N. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Behar Harpaz, S. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ben Ami, S. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benincasa, G.P. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Kuutmann, E.B. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Binet, S. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boehler, M. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Bordoni, S. Borer, C. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boveia, A. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandenburg, G.W. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, B. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brown, G. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. 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Valladolid Gallego, E. Vallecorsa, S. Ferrer, J.A.V. Van Berg, R. van der Graaf, H. van der Kraaij, E. van der Poel, E. van der Ster, D. van Eldik, N. van Gemmeren, P. van Kesteren, Z. van Vulpen, I. Vandelli, W. Vaniachine, A. Vankov, P. Vannucci, F. Vari, R. Varnes, E.W. Varouchas, D. Vartapetian, A. Varvell, K.E. Vasilyeva, L. Vassilakopoulos, V.I. Vazeille, F. Vellidis, C. Veloso, F. Veneziano, S. Ventura, A. Ventura, D. Venturi, M. Venturi, N. Vercesi, V. Verducci, M. Verkerke, W. Vermeulen, J.C. Vetterli, M.C. Vichou, I. Vickey, T. Viehhauser, G.H.A. Villa, M. Villani, E.G. Perez, M.V. Vilucchi, E. Vincter, M.G. Vinek, E. Vinogradov, V.B. Viret, S. Virzi, J. Vitale, A. Vitells, O. Vivarelli, I. Vaque, F.V. Vlachos, S. Vlasak, M. Vlasov, N. Vogel, A. Vokac, P. Volpi, M. von der Schmitt, H. von Loeben, J. von Radziewski, H. von Toerne, E. Vorobel, V. Vorwerk, V. Vos, M. Voss, R. Voss, T.T. Vossebeld, J.H. Vranjes, N. Milosavljevic, M.V. Vrba, V. Vreeswijk, M. Anh, T.V. Vudragovic, D. Vuillermet, R. Vukotic, I. Wagner, P. Walbersloh, J. Walder, J. Walker, R. Walkowiak, W. Wall, R. Wang, C. Wang, H. Wang, J. Wang, S.M. Warburton, A. Ward, C.P. Warsinsky, M. Wastie, R. Watkins, P.M. Watson, A.T. Watson, M.F. Watts, G. Watts, S. Waugh, A.T. Waugh, B.M. Weber, M.D. Weber, M. Weber, M.S. Weber, P. Weidberg, A.R. Weingarten, J. Weiser, C. Wellenstein, H. Wells, P.S. Wen, M. Wenaus, T. Wendler, S. Wengler, T. Wenig, S. Wermes, N. Werner, M. Werner, P. Werth, M. Werthenbach, U. Wessels, M. Whalen, K. White, A. White, M.J. White, S. Whitehead, S.R. Whiteson, D. Whittington, D. Wicek, F. Wicke, D. Wickens, F.J. Wiedenmann, W. Wielers, M. Wienemann, P. Wiglesworth, C. Wiik, L.A.M. Wildauer, A. Wildt, M.A. Wilkens, H.G. Williams, E. Williams, H.H. Willocq, S. Wilson, J.A. Wilson, M.G. Wilson, A. Wingerter-Seez, I. Winklmeier, F. Wittgen, M. Wolter, M.W. Wolters, H. Wosiek, B.K. Wotschack, J. Woudstra, M.J. Wraight, K. Wright, C. Wright, D. Wrona, B. Wu, S.L. Wu, X. Wulf, E. Wynne, B.M. Xaplanteris, L. Xella, S. Xie, S. Xu, D. Xu, N. Yamada, M. Yamamoto, A. Yamamoto, K. Yamamoto, S. Yamamura, T. Yamaoka, J. Yamazaki, T. Yamazaki, Y. Yan, Z. Yang, H. Yang, U.K. Yang, Z. Yao, W.-M. Yao, Y. Yasu, Y. Ye, J. Ye, S. Yilmaz, M. Yoosoofmiya, R. Yorita, K. Yoshida, R. Young, C. Youssef, S.P. Yu, D. Yu, J. Yuan, L. Yurkewicz, A. Zaidan, R. Zaitsev, A.M. Zajacova, Z. Zambrano, V. Zanello, L. Zaytsev, A. Zeitnitz, C. Zeller, M. Zemla, A. Zendler, C. Zenin, O. Zenis, T. Zenonos, Z. Zenz, S. Zerwas, D. della Porta, G.Z. Zhan, Z. Zhang, H. Zhang, J. Zhang, Q. Zhang, X. Zhao, L. Zhao, T. Zhao, Z. Zhemchugov, A. Zhong, J. Zhou, B. Zhou, N. Zhou, Y. Zhu, C.G. Zhu, H. Zhu, Y. Zhuang, X. Zhuravlov, V. Zimmermann, R. Zimmermann, S. Zimmermann, S. Ziolkowski, M. Živković, L. Zobernig, G. Zoccoli, A. zur Nedden, M. Zutshi, V.
Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: The simulation software for the ATLAS Experiment at the Large Hadron Collider is being used for large-scale production of events on the LHC Computing Grid. This simulation requires many components, from the generators that simulate particle collisions, through packages simulating the response of the various detectors and triggers. All of these components come together under the ATLAS simulation infrastructure. In this paper, that infrastructure is discussed, including that supporting the detector description, interfacing the event generation, and combining the GEANT4 simulation of the response of the individual detectors. Also described are the tools allowing the software validation, performance testing, and the validation of the simulated output against known physics processes. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

7. [Microcystic adnexal carcinoma: Mohs micrographic surgery as the treatment of choice]

Author: A, Martorell-Calatayud, C, Requena-Caballero, R, Botella-Estrada, S, Almenar-Medina, O, Sanmartín-Jiménez, B, Llombart-Cussac, E, Nagore-Enguídanos, C, Serra-Guillén, B, Echeverría-García, and C, Guillén-Barona
Subjects: Aged, 80 and over, Male, Skin Neoplasms, Carcinoma, Humans, Female, Facial Neoplasms, Middle Aged, Mohs Surgery, Aged
Abstract: Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck. The tumor can be confused clinically and histologically with other benign and malignant skin lesions, often leading to inappropriate initial treatment. The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision. Recent preliminary studies point to higher cure rates with Mohs micrographic surgery.We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007.In all cases, lesions were located on the head and were primary tumors. Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma. Perineural invasion was not detected in any patient, and all were free of recurrence after between 1 and 12 years of postoperative follow-up.The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors. This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence. The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma.
Published: 2009

8. Radiation-Induced Leiomyosarcoma after Breast Cancer Treatment and TRAM Flap Reconstruction

Author: S. Almenar, B. Merck, M. Olcina, M. J. Giménez-Climent, M. F. Sancho-Merle, C. Vázquez-Albadalejo, and F. Llopis
Subjects: Leiomyosarcoma, medicine.medical_specialty, business.industry, medicine.medical_treatment, Radiation induced, Case Report, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Surgery, Tram flap, Radiation therapy, Therapeutic approach, Breast cancer, Oncology, medicine, Radiology, Nuclear Medicine and imaging, Sarcoma, business, Mastectomy
Abstract: The development of a radiation-induced sarcoma (RIS) in the post mastectomy thoracic treatment volume is an infrequent, but recognized, event. Its frequency is rising in relation with increasing survival of breast cancer patients treated with adjuvant radiation therapy, and is associated with poor prognosis despite treatment. We present a case of leiomyosarcoma in a patient who underwent mastectomy followed by radiotherapy for invasive ductal carcinoma. A delayed TRAM flap reconstruction was performed 10 years after and a rapid growing mass under the reconstructed flap appeared, on routine follow-up, twenty years later. This report analyzes the diagnostic and therapeutic approach of patients with RIS.
Published: 2008

9. Can Axillary Lymphadenectomy Be Avoided in any Case of Sentinel Node Metastasis?

Author: M. Sancho, M. Fliquete Peris, F. Llopis-Martínez, B. Merck, A. Bayón, C. Martínez-Carsí, M. J. Giménez-Climent, S. Almenar-Medina, N. Martínez Alzamora, A. Ruíz, and C. Vázquez-Albadalejo
Subjects: Cancer Research, medicine.medical_specialty, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Sentinel node, Sentinel node metastasis, medicine.disease, Metastasis, Surgery, Breast cancer, Oncology, Axillary Lymphadenectomy, Biopsy, medicine, Lymphadenectomy, Radiology, business, Breast carcinoma
Abstract: INTRODUCTION: Axillary lymphadenectomy is the gold standard for sentinel node metastasis (SN). Metastasis rate of non – sentinel node (NSN) is related to tumor and SN metastasis sizes. In over 50% of cases of SN metastasis, the SN is the only node with neoplasm involvement. We have studied the variables that are known to influence most on SN metastasis (tumor size) and on NSN metastasis (size of the SN metastasis) with the aim to find out a subgroup of patients in whom axillary lymphadenectomy could be avoided despite of SN involvement.OBJECTIVE: To determine if lymphadenectomy is necessary in all patients with SN metastasis.MATERIAL AND METHOD: A sequential and prospectively maintained database was retrospectively searched, for patients staged with SN biopsy for breast carcinoma. We have reviewed 1285 consecutive breast cancer patients treated between December 1998 and April 2009, average age: 55 ± 12.5 years. SN localization was performed with isotopic (34%) or combined technique (66%). SN biopsy was associated to breast conserving technique in 79.8% of cases. The histopathologic study of SN consisted of serial sectioning, H&E and immunohistochemical (IHC) staining.Statistical analyses were performed using SPSS version 15.0 (SPSS Inc, Chicago, Ill). Comparisons of NSN tumoral infiltration among groups (negative SN, isolated tumoral cells (ITC) and SN micrometastasis) related to tumoral size were assessed by univariate analysis with contingency tables and χ2 test. Multivariate analysis was performed using a binary logistic regression model.RESULTS: Identification rate was of 95.8%. SN metastasis was detected in 418 patients, axillary lymphadenectomy was the treatment in 384 cases. The SN was the only metastatic lymph node in 276 patients (71.9%), whereas more involved nodes were found in 108 patients (28.1%). On multivariate analysis, the variables independently associated to SN metastasis were: age (p=0.005), tumor size (p Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 1027.
Published: 2009
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10. Uncommon vascular tumor of the ovary. Primary ovarian epithelioid hemangioendothelioma or vascular sarcomatous transformation in ovarian germ cell tumor?

Author: Illueca C, Machado I, García A, Covisa A, Morales J, Cruz J, Traves V, and Almenar S
Subjects: Adult, Diagnosis, Differential, Female, Hemangioendothelioma, Epithelioid pathology, Hemangioendothelioma, Epithelioid surgery, Humans, Immunohistochemistry, Neoplasms, Germ Cell and Embryonal diagnosis, Neoplasms, Germ Cell and Embryonal pathology, Ovarian Neoplasms pathology, Ovarian Neoplasms surgery, Sarcoma diagnosis, Sarcoma pathology, Ultrasonography, Doppler, Color, Young Adult, Hemangioendothelioma, Epithelioid diagnosis, Ovarian Neoplasms diagnosis
Abstract: Epithelioid hemangioendothelioma (EHE) is an unusual vascular tumor, which usually occurs in the soft tissue, liver, breast, lung and bone. We submit a case of EHE, a tumor never before reported in the ovary. A 20-year-old woman was admitted with a medical history of unilateral ovarian tumor. The right ovary was totally removed and histologically, the tumor was composed of epithelioid cells with eosinophilic cytoplasm and prominent intracytoplasmic vacuoles associated with myxohyaline matrix. No morphologic evidence of germ cell tumor was observed. Immunohistochemically, the tumor cells were positive for CD31 and CD34. However, all germ cell tumor markers were negative. The final diagnosis was EHE of the ovarian gland and sarcomatous transformation in ovarian germ cell tumor was excluded after extensive histopathological and immunohistochemical study. EHE is an uncommon vascular tumor, which is rarely seen in female genital tract and this is the first report of EHE in ovarian gland. Final diagnosis depends on histopathological and immunohistochemical features.
Published: 2011
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11. A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole.

Author: Garcia-Casado Z, Guerrero-Zotano A, Llombart-Cussac A, Calatrava A, Fernandez-Serra A, Ruiz-Simon A, Gavila J, Climent MA, Almenar S, Cervera-Deval J, Campos J, Albaladejo CV, Llombart-Bosch A, Guillem V, and Lopez-Guerrero JA
Subjects: Aged, Aged, 80 and over, Antineoplastic Agents pharmacology, Disease Progression, Female, Humans, Immunohistochemistry methods, Letrozole, Middle Aged, Postmenopause, Treatment Outcome, 3' Untranslated Regions, Aromatase genetics, Breast Neoplasms drug therapy, Breast Neoplasms genetics, Neoadjuvant Therapy methods, Nitriles pharmacology, Polymorphism, Genetic, Triazoles pharmacology
Abstract: Background: Aromatase (CYP19A1) regulates estrogen biosynthesis. Polymorphisms in CYP19A1 have been related to the pathogenesis of breast cancer (BC). Inhibition of aromatase with letrozole constitutes the best option for treating estrogen-dependent BC in postmenopausal women. We evaluate a series of polymorphisms of CYP19A1 and their effect on response to neoadjuvant letrozole in early BC., Methods: We analyzed 95 consecutive postmenopausal women with stage II-III ER/PgR [+] BC treated with neoadjuvant letrozole. Response to treatment was measured by radiology at 4th month by World Health Organization (WHO) criteria. Three polymorphisms of CYP19A1, one in exon 7 (rs700519) and two in the 3'-UTR region (rs10046 and rs4646) were evaluated on DNA obtained from peripheral blood., Results: Thirty-five women (36.8%) achieved a radiological response to letrozole. The histopathological and immunohistochemical parameters, including hormonal receptor status, were not associated with the response to letrozole. Only the genetic variants (AC/AA) of the rs4646 polymorphism were associated with poor response to letrozole (p = 0.03). Eighteen patients (18.9%) reported a progression of the disease. Those patients carrying the genetic variants (AC/AA) of rs4646 presented a lower progression-free survival than the patients homozygous for the reference variant (p = 0.0686). This effect was especially significant in the group of elderly patients not operated after letrozole induction (p = 0.009)., Conclusions: Our study reveals that the rs4646 polymorphism identifies a subgroup of stage II-III ER/PgR [+] BC patients with poor response to neoadjuvant letrozole and poor prognosis. Testing for the rs4646 polymorphism could be a useful tool in order to orientate the treatment in elderly BC patients.
Published: 2010
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12. Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer.

Author: Martín M, Rodríguez-Lescure A, Ruiz A, Alba E, Calvo L, Ruiz-Borrego M, Munárriz B, Rodríguez CA, Crespo C, de Alava E, López García-Asenjo JA, Guitián MD, Almenar S, González-Palacios JF, Vera F, Palacios J, Ramos M, Gracia Marco JM, Lluch A, Alvarez I, Seguí MA, Mayordomo JI, Antón A, Baena JM, Plazaola A, Modolell A, Pelegrí A, Mel JR, Aranda E, Adrover E, Alvarez JV, García Puche JL, Sánchez-Rovira P, Gonzalez S, and López-Vega JM
Subjects: Adult, Aged, Antineoplastic Agents, Phytogenic administration & dosage, Antineoplastic Agents, Phytogenic adverse effects, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Antineoplastic Combined Chemotherapy Protocols adverse effects, Breast Neoplasms chemistry, Carcinoma, Ductal, Breast drug therapy, Carcinoma, Ductal, Breast secondary, Carcinoma, Lobular drug therapy, Carcinoma, Lobular secondary, Cyclophosphamide administration & dosage, Disease-Free Survival, Drug Administration Schedule, Epirubicin administration & dosage, Female, Fluorouracil administration & dosage, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Infusions, Intravenous, Kaplan-Meier Estimate, Middle Aged, Neoplasm Staging, Paclitaxel administration & dosage, Paclitaxel adverse effects, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Receptor, ErbB-2 analysis, Receptors, Estrogen analysis, Receptors, Progesterone analysis, Treatment Outcome, Antineoplastic Agents, Phytogenic therapeutic use, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Biomarkers, Tumor analysis, Breast Neoplasms drug therapy, Breast Neoplasms pathology, Paclitaxel therapeutic use
Abstract: Background: Taxanes are among the most active drugs for the treatment of metastatic breast cancer, and, as a consequence, they have also been studied in the adjuvant setting., Methods: After breast cancer surgery, women with lymph node-positive disease were randomly assigned to treatment with fluorouracil, epirubicin, and cyclophosphamide (FEC) or with FEC followed by weekly paclitaxel (FEC-P). The primary endpoint of study-5-year disease-free survival (DFS)-was assessed by Kaplan-Meier analysis. Secondary endpoints included overall survival and analysis of the prognostic and predictive value of clinical and molecular (hormone receptors by immunohistochemistry and HER2 by fluorescence in situ hybridization) markers. Associations and interactions were assessed with a multivariable Cox proportional hazards model for DFS for the following covariates: age, menopausal status, tumor size, lymph node status, type of chemotherapy, tumor size, positive lymph nodes, HER2 status, and hormone receptor status. All statistical tests were two-sided., Results: Among the 1246 eligible patients, estimated rates of DFS at 5 years were 78.5% in the FEC-P arm and 72.1% in the FEC arm (difference = 6.4%, 95% confidence interval [CI] = 1.6% to 11.2%; P = .006). FEC-P treatment was associated with a 23% reduction in the risk of relapse compared with FEC treatment (146 relapses in the 614 patients in the FEC-P arm vs 193 relapses in the 632 patients in the FEC arm, hazard ratio [HR] = 0.77, 95% CI = 0.62 to 0.95; P = .022) and a 22% reduction in the risk of death (73 and 95 deaths, respectively, HR = 0.78, 95% CI = 0.57 to 1.06; P = .110). Among the 928 patients for whom tumor samples were centrally analyzed, type of chemotherapy (FEC vs FEC-P) (P = .017), number of involved axillary lymph nodes (P < .001), tumor size (P = .020), hormone receptor status (P = .004), and HER2 status (P = .006) were all associated with DFS. We found no statistically significant interaction between HER2 status and paclitaxel treatment or between hormone receptor status and paclitaxel treatment., Conclusions: Among patients with operable breast cancer, FEC-P treatment statistically significantly reduced the risk of relapse compared with FEC as adjuvant therapy.
Published: 2008
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13. Radiation-Induced Leiomyosarcoma after Breast Cancer Treatment and TRAM Flap Reconstruction.

Author: Olcina M, Merck B, Giménez-Climent MJ, Almenar S, Sancho-Merle MF, Llopis F, and Vázquez-Albadalejo C
Abstract: The development of a radiation-induced sarcoma (RIS) in the post mastectomy thoracic treatment volume is an infrequent, but recognized, event. Its frequency is rising in relation with increasing survival of breast cancer patients treated with adjuvant radiation therapy, and is associated with poor prognosis despite treatment. We present a case of leiomyosarcoma in a patient who underwent mastectomy followed by radiotherapy for invasive ductal carcinoma. A delayed TRAM flap reconstruction was performed 10 years after and a rapid growing mass under the reconstructed flap appeared, on routine follow-up, twenty years later. This report analyzes the diagnostic and therapeutic approach of patients with RIS.
Published: 2008
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14. Histological characterisation of small renal masses and incidence of silent renal masses.

Author: Almenar Medina S and Calatrava Fons A
Abstract: With the introduction of sonographic and CT examinations, the number of small renal masses detected has increased. Benign neoplastic lesions are usually smaller than 4 cm in size, whilst the most common types of renal cell carcinomas have a mean size greater than that, but we must not forget that a significant number of small masses are renal cell carcinomas; even though the rate of benign cases increases as the diameter of the lesions decreases, therefore, size itself cannot be used to rule out a diagnostic of malignancy and often image characteristics are not enough to predict the nature of the lesion with certainty. In this case, histological confirmation must be recommended. Ideally, the histological study must be conducted on the surgical specimen, even though biopsy can be an option in selected cases.
Published: 2008
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1. Anatomy, immunohistochemistry, and numerical distribution of human splenic microvessels

2. Microcystic Adnexal Carcinoma: Mohs Micrographic Surgery as the Treatment of Choice

3. Carcinoma anexial microquístico: la cirugía micrográfica de Mohs como tratamiento de elección

4. The ATLAS Inner Detector commissioning and calibration

5. Commissioning of the ATLAS Muon Spectrometer with cosmic rays

6. The ATLAS Simulation Infrastructure

7. [Microcystic adnexal carcinoma: Mohs micrographic surgery as the treatment of choice]

8. Radiation-Induced Leiomyosarcoma after Breast Cancer Treatment and TRAM Flap Reconstruction

9. Can Axillary Lymphadenectomy Be Avoided in any Case of Sentinel Node Metastasis?

10. Uncommon vascular tumor of the ovary. Primary ovarian epithelioid hemangioendothelioma or vascular sarcomatous transformation in ovarian germ cell tumor?

11. A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole.

12. Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer.

13. Radiation-Induced Leiomyosarcoma after Breast Cancer Treatment and TRAM Flap Reconstruction.

14. Histological characterisation of small renal masses and incidence of silent renal masses.

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